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Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

Powered by Cytoscape Web for: parental proteins ZBTB21 (from a repository: Wed Nov 16 10:21:52 2016)
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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)15
The number (and %) of the onco-proteins2 (13.33 %)
The number (and %) of the tumor suppressors0 (0.00 %)
Total number of binary PPIs (saturation %)25 (23.81 %)
The number (and %) of affected PPIs15 (60.00 %)
The number of possible different fusions4
PPI diameter2
PPI radius1
The average degree of PPI2.267
Assortativity coefficient-0.6190
The network average Clustering coefficient0.313
The number (and %) of a zero Clustering coefficients9 (60.00 %)
The number (and %) of a zero Betweenness Centrality13 (86.67 %)

ACTIVE INTERACTORS


List of the fusions

PPI for parental proteins: ZBTB21 All fusions
: DL056401; DL056248;
Proteins found in more fusions CREB1 (see 2 fusions); ZBTB21 (see 1 fusions); YWHAG (see 1 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 ZBTB21parental protein150.033175.000BTB (PF00651, IPR013069, SM00225): BTB/POZ domain
Mut7-C (PF01927, IPR002782): Mut7-C RNAse domain
zf-BED (PF02892, IPR003656, SM00614): BED zinc finger
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-CHCC (PF10276, IPR019401, SM00400): Zinc-finger domain
zf-met (PF12874): Zinc-finger of C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger
zf-C2H2_11 (PF16622, IPR007087): zinc-finger C2H2-type
2 CASQ2interactor21.0000Calsequestrin (PF01216, IPR001393): Calsequestrin
SDA1 (PF05285, IPR007949): SDA1
3 CCDC8interactor40.6671.000Borrelia_P83 (PF05262, IPR007926): Borrelia P83/100 protein
SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal
PNMA (PF14893, IPR026523): PNMA
4 CREB1oncoprotein31.0000bZIP_1 (PF00170, IPR004827): bZIP transcription factor
pKID (PF02173, IPR003102): pKID domain
DUF4988 (PF16378, IPR032149): Domain of unknown function
5 DYNLT1interactor100Tctex-1 (PF03645, IPR005334): Tctex-1 family
6 FHL3interactor31.0000LIM (PF00412, IPR001781, SM00132): LIM domain
Med27 (PF11571, IPR021627): Mediator complex subunit 27
7 GSTA1interactor200GST_C (PF00043, IPR004046): Glutathione S-transferase, C-terminal domain
GST_N (PF02798, IPR004045): Glutathione S-transferase, N-terminal domain
8 KLHL29interactor100BACK (PF07707, IPR011705, SM00875): BTB And C-terminal Kelch
BTB (PF00651, IPR013069, SM00225): BTB/POZ domain
Kelch_1 (PF01344, IPR006652, SM00612): Kelch motif
Kelch_5 (PF13854): Kelch motif
Kelch_6 (PF13964): Kelch motif
9 NAP1L5interactor100NAP (PF00956, IPR002164): Nucleosome assembly protein (NAP)
SspB (PF04386, IPR007481): Stringent starvation protein B
Trypan_PARP (PF05887, IPR008882): Procyclic acidic repetitive protein (PARP)
10 OTUB1interactor100Peptidase_C65 (PF10275, IPR019400): Peptidase C65 Otubain
11 PASKinteractor100Pkinase (PF00069, IPR000719): Protein kinase domain
PAS_8 (PF13188, IPR000014): PAS domain
PAS_9 (PF13426, IPR000014): PAS domain
12 PPP2R2Binteractor100WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
13 SUMO2interactor200Rad60-SLD (PF11976, IPR022617): Ubiquitin-2 like Rad60 SUMO-like
14 YWHAGprotein found in more fusions31.000014-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
15 ZBTB14interactor200BTB (PF00651, IPR013069, SM00225): BTB/POZ domain
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger

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