Find Fusion Network

Enter
Fusion ID:
Protein names:


Level of PPIs:
or Upload text file:
Update repository
Visible interactions: all affected independent (normal) missing (in fusions) nothing (blank)

Visualization interactions

Powered by Cytoscape Web for: parental proteins YY1 (from a repository: Sat Nov 19 08:37:47 2016)
Examples

Cytoscape Web will replace the contents your graph
PPI Properties:

Click on nodes
or edges

Layout Tree
Circle
Radial
Force Directed
Preset
Export graph
PDF file
SVG file
SIF file
XML file
GraphML file

Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)121
The number (and %) of the onco-proteins39 (32.23 %)
The number (and %) of the tumor suppressors28 (23.14 %)
Total number of binary PPIs (saturation %)879 (12.11 %)
The number (and %) of affected PPIs121 (13.77 %)
The number of possible different fusions29
PPI diameter2
PPI radius1
The average degree of PPI13.554
Assortativity coefficient-0.2536
The network average Clustering coefficient0.540
The number (and %) of a zero Clustering coefficients4 (3.31 %)
The number (and %) of a zero Betweenness Centrality14 (11.57 %)

ACTIVE INTERACTORS
MISSING INTERACTORS (in fusions)


List of the fusions

PPI for parental proteins: YY1 All fusions
: BM924295;
Proteins found in more fusions APP (see 4 fusions); SMAD4 (see 2 fusions); NPM1 (see 1 fusions); BCL6 (see 2 fusions); HDAC4 (see 1 fusions); NFKB1 (see 2 fusions); CREB1 (see 2 fusions); YY1 (see 2 fusions); MYC (see 1 fusions); SP1 (see 1 fusions); CREBBP (see 5 fusions); NEDD4L (see 3 fusions); KAT2B (see 1 fusions); PRKDC (see 3 fusions); SMURF2 (see 1 fusions); TCF3 (see 3 fusions); HDAC5 (see 1 fusions); EZH2 (see 1 fusions); EP300 (see 1 fusions); HCFC1 (see 2 fusions); DDX5 (see 1 fusions); RING1 (see 1 fusions); PCGF2 (see 1 fusions); NEDD4 (see 1 fusions); NCL (see 3 fusions); TP53 (see 3 fusions); SMAD3 (see 3 fusions); SUZ12 (see 2 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 YY1parental protein1210.0988527.308zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger
Keratin_2_tail (PF16210, IPR032449): Keratin type II cytoskeletal 1 tail
2 ACTL6Ainteractor210.52470.170Actin (PF00022, IPR004000, SM00268): Actin
3 ACTR5interactor141.0000Actin (PF00022, IPR004000, SM00268): Actin
DUF1542 (PF07564, IPR011439): Domain of Unknown Function (DUF1542)
UPF0449 (PF15136, IPR028227): Uncharacterised protein family UPF0449
4 ACTR8interactor151.0000Actin (PF00022, IPR004000, SM00268): Actin
5 APPprotein found in more fusions210.23293.157APP_N (PF02177, IPR015849, SM00006): Amyloid A4 N-terminal heparin-binding
Beta-APP (PF03494, IPR013803): Beta-amyloid peptide (beta-APP)
BUD22 (PF09073, IPR015158): BUD22
IncA (PF04156, IPR007285): IncA protein
Kunitz_BPTI (PF00014, IPR002223, SM00131): Kunitz/Bovine pancreatic trypsin inhibitor domain
APP_amyloid (PF10515, IPR019543): beta-amyloid precursor protein C-terminus
APP_Cu_bd (PF12924, IPR011178): Copper-binding of amyloid precursor, CuBD
APP_E2 (PF12925, IPR024329): E2 domain of amyloid precursor protein
6 ARRB1interactor80.5006.174Arrestin_C (PF02752, IPR011022, SM01017): Arrestin (or S-antigen), C-terminal domain
Arrestin_N (PF00339, IPR011021): Arrestin (or S-antigen), N-terminal domain
7 ATF2oncoprotein120.49110.186bZIP_1 (PF00170, IPR004827): bZIP transcription factor
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
8 ATF6interactor50.5001.202bZIP_1 (PF00170, IPR004827): bZIP transcription factor
DUF2749 (PF10907, IPR024475): Protein of unknown function (DUF2749)
9 ATF7interactor30.6670.250bZIP_1 (PF00170, IPR004827): bZIP transcription factor
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
10 BAP1suppressor40.6672.000Peptidase_C12 (PF01088, IPR001578): Ubiquitin carboxyl-terminal hydrolase, family 1
TFIIIC_delta (PF12657, IPR024761): Transcription factor IIIC subunit delta N-term
11 BAXsuppressor70.8000.767Bcl-2 (PF00452, IPR026298): Apoptosis regulator proteins, Bcl-2 family
12 BCL6oncoprotein140.38526.306BTB (PF00651, IPR013069, SM00225): BTB/POZ domain
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-C2H2_jaz (PF12171, IPR022755): Zinc-finger double-stranded RNA-binding
DZR (PF12773, IPR025874): Double zinc ribbon
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2HE (PF16278, IPR032566): C2HE / C2H2 / C2HC zinc-binding finger
13 BMI1oncoprotein220.34868.536zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
RAWUL (PF16207, IPR032443): RAWUL domain RING finger- and WD40-associated ubiquitin-like
14 CDKN2Asuppressor110.7093.279Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
Ank_5 (PF13857): Ankyrin repeats (many copies)
15 CEP164interactor30.6670.333DUF883 (PF05957, IPR010279): Bacterial protein of unknown function (DUF883)
DUF948 (PF06103, IPR009293): Bacterial protein of unknown function (DUF948)
TBPIP (PF07106, IPR010776): Tat binding protein 1(TBP-1)-interacting protein (TBPIP)
WW (PF00397, IPR001202, SM00456): WW domain
KxDL (PF10241, IPR019371): Uncharacterized conserved protein
XhlA (PF10779, IPR019715): Haemolysin XhlA
KfrA_N (PF11740, IPR021104): Plasmid replication region DNA-binding N-term
DUF3807 (PF12720, IPR024526): Protein of unknown function (DUF3807)
16 CREB1oncoprotein150.35238.690bZIP_1 (PF00170, IPR004827): bZIP transcription factor
pKID (PF02173, IPR003102): pKID domain
DUF4988 (PF16378, IPR032149): Domain of unknown function
17 CREBBPsuppressor280.37092.930Creb_binding (PF09030, IPR014744): Creb binding
DUF902 (PF06001, IPR010303): Domain of Unknown Function (DUF902)
Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region
KIX (PF02172, IPR003101): KIX domain
MAS20 (PF02064, IPR002056): MAS20 protein import receptor
TPX2 (PF06886, IPR027329): Targeting protein for Xklp2 (TPX2)
zf-TAZ (PF02135, IPR000197, SM00551): TAZ zinc finger
ANAPC_CDC26 (PF10471, IPR018860): Anaphase-promoting complex APC subunit CDC26
HAT_KAT11 (PF08214, IPR013178): Histone acetylation protein
Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type
DUF3729 (PF12526, IPR022202): Protein of unknown function (DUF3729)
DUF4834 (PF16118, IPR032272): Domain of unknown function (DUF4834)
18 CRKLoncoprotein30.6670.667SH2 (PF00017, IPR000980, SM00252): SH2 domain
SH3_2 (PF07653, IPR011511): Variant SH3 domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
19 CTCFsuppressor70.5712.716cwf18 (PF08315, IPR013169): cwf18 pre-mRNA splicing factor
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger
zf-H2C2_5 (PF13909): C2H2-type zinc-finger domain
PBP1_TM (PF14812, IPR032730): Transmembrane domain of transglycosylase PBP1 at N-terminal
20 DDX3Xsuppressor140.37419.118DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
DUF755 (PF05501, IPR008474): Domain of unknown function (DUF755)
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
21 DDX5oncoprotein170.56714.409DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
P68HR (PF08061, IPR012587): P68HR (NUC004) repeat
ResIII (PF04851, IPR006935): Type III restriction enzyme, res subunit
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
22 DNMT3Linteractor130.44922.187CEBP_ZZ (PF16366, IPR032296): Cytoplasmic polyadenylation element-binding protein ZZ domain
23 EEDsuppressor290.331117.359WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
24 ELAVL1oncoprotein380.173398.419RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
25 EP300oncoprotein410.267293.672Creb_binding (PF09030, IPR014744): Creb binding
DUF902 (PF06001, IPR010303): Domain of Unknown Function (DUF902)
Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region
KIX (PF02172, IPR003101): KIX domain
RR_TM4-6 (PF06459, IPR009460): Ryanodine Receptor TM 4-6
TPX2 (PF06886, IPR027329): Targeting protein for Xklp2 (TPX2)
zf-TAZ (PF02135, IPR000197, SM00551): TAZ zinc finger
HAT_KAT11 (PF08214, IPR013178): Histone acetylation protein
Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type
26 EZH2suppressor160.45724.162CDC45 (PF02724, IPR003874): CDC45-like protein
TCR (PF03638, IPR005172, SM01114): Tesmin/TSO1-like CXC domain, cysteine-rich domain
SET (PF00856, IPR001214, SM00317): SET domain
EZH2_WD-Binding (PF11616, IPR021654): WD repeat binding protein EZH2
Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal
27 FKBP1Ainteractor40.6670.286FKBP_C (PF00254, IPR001179): FKBP-type peptidyl-prolyl cis-trans isomerase
Hemopexin (PF00045, IPR018487, SM00120): Hemopexin
28 FKBP3interactor80.5715.862FKBP_C (PF00254, IPR001179): FKBP-type peptidyl-prolyl cis-trans isomerase
29 FOXB1interactor40.6670.571Forkhead (PF00250, IPR001766, SM00339): Forkhead domain
30 FOXJ2interactor70.5247.071SARAF (PF06682, IPR009567): SOCE-associated regulatory factor of calcium homoeostasis
DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360)
Forkhead (PF00250, IPR001766, SM00339): Forkhead domain
Spt20 (PF12090, IPR021950): Spt20 family
Pro-rich (PF15240, IPR026086): Proline-rich
31 FOXL1oncoprotein31.0000Forkhead (PF00250, IPR001766, SM00339): Forkhead domain
32 FOXN1interactor40.6671.067Forkhead (PF00250, IPR001766, SM00339): Forkhead domain
33 GABPAinteractor90.47213.286Ets (PF00178, IPR000418, SM00413): Ets-domain
SAM_PNT (PF02198, IPR003118, SM00251): Sterile alpha motif (SAM)/Pointed domain
GABP-alpha (PF11620, IPR024668): GA-binding protein alpha chain
Wap1 (PF16997, IPR031550): Wap1 domain
34 GABPB1oncoprotein40.5002.333Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
AAA_23 (PF13476): AAA domain
Ank_4 (PF13637): Ankyrin repeats (many copies)
DUF4265 (PF14085, IPR025361): Domain of unknown function (DUF4265)
35 GRNoncoprotein40.5001.867Granulin (PF00396, IPR000118, SM00277): Granulin
Lustrin_cystein (PF14625, IPR028150): Lustrin, cysteine-rich repeated domain
36 HCFC1protein found in more fusions130.40920.783fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
Kelch_1 (PF01344, IPR006652, SM00612): Kelch motif
Kelch_3 (PF13415): Galactose oxidase, central domain
Kelch_5 (PF13854): Kelch motif
zf-tcix (PF14952, IPR029269): Putative treble-clef, zinc-finger, Zn-binding
37 HDAC1suppressor430.259333.610FSAP_sig_propep (PF03032, IPR004275): Frog skin active peptide family signal and propeptide
Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
38 HDAC2suppressor360.245246.067Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
NARP1 (PF12569, IPR021183): NMDA receptor-regulated protein 1
39 HDAC3suppressor180.38234.231Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
40 HDAC4oncoprotein120.38216.953Borrelia_P83 (PF05262, IPR007926): Borrelia P83/100 protein
Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
HDAC4_Gln (PF12203, IPR024643): Glutamine rich N terminal domain of histone deacetylase 4
41 HDAC5protein found in more fusions230.30771.983Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
NOA36 (PF06524, IPR010531): NOA36 protein
Activator_LAG-3 (PF11498, IPR021587): Transcriptional activator LAG-3
HDAC4_Gln (PF12203, IPR024643): Glutamine rich N terminal domain of histone deacetylase 4
42 HOXA11oncoprotein31.0000DTHCT (PF08070, IPR012542): DTHCT (NUC029) region
Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
DUF3528 (PF12045, IPR021918): Protein of unknown function (DUF3528)
43 HSPA4interactor220.30771.875Herpes_ICP4_N (PF03584, IPR005206): Herpesvirus ICP4-like protein N-terminal region
HSP70 (PF00012, IPR013126): Hsp70 protein
TP53IP5 (PF15331, IPR029290): Cellular tumour antigen p53-inducible 5
44 HSPA5oncoprotein150.45122.078HSP70 (PF00012, IPR013126): Hsp70 protein
45 ILF3oncoprotein160.45829.680dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif
DZF (PF07528, IPR006561, SM00572): DZF domain
46 INO80interactor150.8868.000Peptidase_S49_N (PF08496, IPR013703): Peptidase family S49 N-terminal
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
RNA_pol_Rbc25 (PF08292, IPR013238): RNA polymerase III subunit Rpc25
SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain
POTRA (PF07244, IPR010827): Surface antigen variable number repeat
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
DBINO (PF13892, IPR020838): DNA-binding domain
FAM176 (PF14851): FAM176 family
MAP17 (PF15807, IPR031627): Membrane-associated protein 117 kDa, PDZK1-interacting protein 1
47 INO80Binteractor141.0000PAPA-1 (PF04795, IPR006880): PAPA-1-like conserved region
zf-HIT (PF04438, IPR007529): HIT zinc finger
DUF3619 (PF12279, IPR022064): Protein of unknown function (DUF3619)
IHABP4_N (PF16174, IPR032381): Intracellular hyaluronan-binding protein 4 N-terminal
48 INO80Cinteractor150.8866.675YL1_C (PF08265, IPR013272, SM00993): YL1 nuclear protein C-terminal domain
49 INO80Dinteractor141.0000WRC (PF08879, IPR014977): WRC
zf-C3Hc3H (PF13891, IPR025927): Potential DNA-binding domain
50 INO80Einteractor150.87611.333NBP1 (PF08537, IPR013743): Fungal Nap binding protein NBP1
51 JUNBoncoprotein80.6433.144bZIP_1 (PF00170, IPR004827): bZIP transcription factor
Jun (PF03957, IPR005643): Jun-like transcription factor
52 JUNDoncoprotein70.4762.703bZIP_1 (PF00170, IPR004827): bZIP transcription factor
Jun (PF03957, IPR005643): Jun-like transcription factor
53 KAT2Bprotein found in more fusions160.57113.934Acetyltransf_1 (PF00583, IPR000182): Acetyltransferase (GNAT) family
PCAF_N (PF06466, IPR009464): PCAF (P300/CBP-associated factor) N-terminal domain
Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
54 KMT2Einteractor50.8000.393CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
PHD (PF00628, IPR019787, SM00249): PHD-finger
SET (PF00856, IPR001214, SM00317): SET domain
MSA-2c (PF12238, IPR021060): Merozoite surface antigen 2c
DUF4124 (PF13511, IPR025392): Domain of unknown function (DUF4124)
PHD_3 (PF13922, IPR026905): PHD domain of transcriptional enhancer, Asx
DUF4666 (PF15697, IPR031421): Domain of unknown function (DUF4666)
PRIMA1 (PF16101): Proline-rich membrane anchor 1
55 LAMC2interactor100APG6 (PF04111, IPR007243): Autophagy protein Apg6
ERM (PF00769, IPR011259): Ezrin/radixin/moesin family
FUSC (PF04632, IPR006726): Fusaric acid resistance protein family
Ephrin_rec_like (PF07699, IPR011641): Putative ephrin-receptor like
Laminin_B (PF00052, IPR000034): Laminin B (Domain IV)
Laminin_II (PF06009, IPR010307): Laminin Domain II
Rho_Binding (PF08912, IPR015008): Rho Binding
Laminin_EGF (PF00053, IPR002049, SM00180): Laminin EGF domain
TNFR_c6 (PF00020, IPR001368, SM00208): TNFR/NGFR cysteine-rich region
Alanine_zipper (PF11839, IPR021793): Alanine-zipper, major outer membrane lipoprotein
hEGF (PF12661, IPR013032): Human growth factor-like EGF
56 MAXsuppressor110.44410.493ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16)
HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
SlyX (PF04102, IPR007236): SlyX
57 MCRS1interactor150.8868.000FHA (PF00498, IPR000253, SM00240): FHA domain
MCRS_N (PF13325, IPR025999): N-terminal region of micro-spherule protein
58 MDM2oncoprotein270.36090.902Pinin_SDK_N (PF04697, IPR006787): pinin/SDK conserved region
Presenilin (PF01080, IPR001108): Presenilin
SWIB (PF02201, IPR003121, SM00151): SWIB/MDM2 domain
zf-FPG_IleRS (PF06827, IPR010663): Zinc finger found in FPG and IleRS
zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others
zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
59 MECP2interactor90.4448.862K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain
MBD (PF01429, IPR001739, SM00391): Methyl-CpG binding domain
SelP_N (PF04592, IPR007671): Selenoprotein P, N terminal region
IHABP4_N (PF16174, IPR032381): Intracellular hyaluronan-binding protein 4 N-terminal
60 MTA2interactor110.5459.784BAH (PF01426, IPR001025, SM00439): BAH domain
ELM2 (PF01448, IPR000949): ELM2 domain
Resolvase (PF00239, IPR006119, SM00857): Resolvase, N terminal domain
DDA1 (PF10172, IPR018276): Det1 complexing ubiquitin ligase
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
GATA (PF00320, IPR000679, SM00401): GATA zinc finger
61 MYConcoprotein280.36294.828HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
Myc-LZ (PF02344, IPR003327): Myc leucine zipper domain
Myc_N (PF01056, IPR012682): Myc amino-terminal region
62 NCLprotein found in more fusions210.44240.073DUF1754 (PF08555, IPR013865): Eukaryotic family of unknown function (DUF1754)
Myc_N (PF01056, IPR012682): Myc amino-terminal region
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
YL1 (PF05764, IPR008895): YL1 nuclear protein
Limkain-b1 (PF11608, IPR024582): Limkain b1
63 NEDD4suppressor130.30331.282Rota_NS26 (PF01525, IPR002512): Rotavirus NS26
WW (PF00397, IPR001202, SM00456): WW domain
HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
64 NEDD4Lsuppressor80.4295.456WW (PF00397, IPR001202, SM00456): WW domain
HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
65 NFE2L2oncoprotein60.8670.321bZIP_Maf (PF03131, IPR004826): bZIP Maf transcription factor
66 NFKB1suppressor160.41027.920Death (PF00531, IPR000488, SM00005): Death domain
GHMP_kinases_C (PF08544, IPR013750): GHMP kinases C terminal
RHD_DNA_bind (PF00554, IPR011539): Rel homology DNA-binding domain
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
Ank_4 (PF13637): Ankyrin repeats (many copies)
RHD_dimer (PF16179, IPR032397): Rel homology dimerisation domain
67 NFRKBinteractor150.87611.333ATP-synt_E (PF05680, IPR008386): ATP synthase E chain
PSRT (PF07636, IPR011504): PSRT
Apt1 (PF10351, IPR019443): Golgi-body localisation protein domain
NFRKB_winged (PF14465, IPR025220): NFRKB Winged Helix-like
SUIM_assoc (PF16619): Unstructured region C-term to UIM in Ataxin3
68 NOTCH1suppressor160.39028.355Ank (PF00023, IPR002110, SM00248): Ankyrin repeat
EGF (PF00008, IPR000742, SM00181): EGF-like domain
EGF_2 (PF07974, IPR013111): EGF-like domain
EGF_alliinase (PF04863, IPR006947): Alliinase EGF-like domain
EGF_CA (PF07645, IPR001881, SM00179): Calcium-binding EGF domain
NOD (PF06816, IPR010660): NOTCH protein
NODP (PF07684, IPR011656): NOTCH protein
TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
Notch (PF00066, IPR000800, SM00004): LNR domain
DUF3454 (PF11936, IPR024600): Domain of unknown function (DUF3454)
hEGF (PF12661, IPR013032): Human growth factor-like EGF
cEGF (PF12662, IPR026823): Complement Clr-like EGF-like
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
69 NPM1suppressor210.37457.290Nucleoplasmin (PF03066): Nucleoplasmin
SDA1 (PF05285, IPR007949): SDA1
NPM1-C (PF16276, IPR032569): Nucleophosmin C-terminal domain
70 NR1H2oncoprotein30.6670.400zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains)
Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
71 PCGF2suppressor80.8101.317zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
RAWUL (PF16207, IPR032443): RAWUL domain RING finger- and WD40-associated ubiquitin-like
72 PPIAinteractor50.4001.627Pro_isomerase (PF00160, IPR002130): Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD
73 PPP1R3Binteractor100CBM_21 (PF03370, IPR005036): Carbohydrate/starch-binding module (family 21)
74 PRKDCprotein found in more fusions200.43930.881FAT (PF02259, IPR003151): FAT domain
FATC (PF02260, IPR003152): FATC domain
NUC194 (PF08163, IPR012582): NUC194 domain
PI3_PI4_kinase (PF00454, IPR000403, SM00146): Phosphatidylinositol 3- and 4-kinase
75 PRMT1interactor100.5564.695Methyltransf_25 (PF13649): Methyltransferase domain
76 PSMD9interactor40.6672.000Remorin_C (PF03763, IPR005516): Remorin, C-terminal region
DUF2046 (PF09755, IPR019152): Uncharacterized conserved protein H4 (DUF2046)
PDZ_2 (PF13180, IPR001478): PDZ domain
77 RAF1oncoprotein90.3219.447Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
RBD (PF02196, IPR003116, SM00455): Raf-like Ras-binding domain
C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain)
78 RB1suppressor200.37957.272RB_A (PF01858, IPR002720): Retinoblastoma-associated protein A domain
RB_B (PF01857, IPR002719): Retinoblastoma-associated protein B domain
Rb_C (PF08934, IPR015030): Rb C-terminal domain
DUF3452 (PF11934, IPR024599): Domain of unknown function (DUF3452)
DUF4592 (PF15262, IPR028030): Domain of unknown function (DUF4592)
79 RELBoncoprotein50.5002.467RHD_DNA_bind (PF00554, IPR011539): Rel homology DNA-binding domain
RHD_dimer (PF16179, IPR032397): Rel homology dimerisation domain
RelB_leu_zip (PF16180, IPR032399): RelB leucine zipper
RelB_transactiv (PF16181, IPR032400): RelB transactivation domain
80 RING1protein found in more fusions160.41028.456zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
RAWUL (PF16207, IPR032443): RAWUL domain RING finger- and WD40-associated ubiquitin-like
81 RNF2interactor310.297157.552zf-C4_Topoisom (PF01396, IPR013498): Topoisomerase DNA binding C4 zinc finger
zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
RAWUL (PF16207, IPR032443): RAWUL domain RING finger- and WD40-associated ubiquitin-like
82 RUVBL1oncoprotein250.43893.226TIP49 (PF06068, IPR010339): TIP49 C-terminus
83 RUVBL2oncoprotein320.348190.594TIP49 (PF06068, IPR010339): TIP49 C-terminus
84 RYBPinteractor100.6448.850DUF11 (PF01345, IPR001434): Domain of unknown function DUF11
fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region
I-set (PF07679, IPR013098): Immunoglobulin I-set domain
Pkinase (PF00069, IPR000719): Protein kinase domain
PPAK (PF02818, IPR004168): PPAK motif
Titin_Z (PF09042, IPR015129): Titin Z
V-set (PF07686, IPR013106): Immunoglobulin V-set domain
Y_Y_Y (PF07495, IPR011123): Y_Y_Y domain
DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369)
Ig_3 (PF13927): Immunoglobulin domain
85 SAP30interactor50.7000.821Titin_Z (PF09042, IPR015129): Titin Z
zf-SAP30 (PF13866, IPR025717): SAP30 zinc-finger
SAP30_Sin3_bdg (PF13867, IPR025718): Sin3 binding region of histone deacetylase complex subunit SAP30
86 SHFM1interactor30.6671.000CLLAC (PF15675, IPR031379): CLLAC-motif containing domain
87 SKP2suppressor100.48913.484LRR_1 (PF00560, IPR001611): Leucine Rich Repeat
LRR_2 (PF07723, IPR013101): Leucine Rich Repeat
LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies)
F-box-like (PF12937, IPR001810): F-box-like
LRR_6 (PF13516, IPR001611): Leucine Rich repeat
LRR_8 (PF13855, IPR001611): Leucine rich repeat
88 SLC39A7interactor30.6670.182Zip (PF02535, IPR003689): ZIP Zinc transporter
89 SMAD1interactor130.6368.979MH1 (PF03165, IPR003619, SM00523): MH1 domain
MH2 (PF03166, IPR001132, SM00524): MH2 domain
90 SMAD2suppressor190.50332.440MH1 (PF03165, IPR003619, SM00523): MH1 domain
MH2 (PF03166, IPR001132, SM00524): MH2 domain
91 SMAD3oncoprotein300.310146.537MH1 (PF03165, IPR003619, SM00523): MH1 domain
MH2 (PF03166, IPR001132, SM00524): MH2 domain
92 SMAD4suppressor170.49228.476MH1 (PF03165, IPR003619, SM00523): MH1 domain
MH2 (PF03166, IPR001132, SM00524): MH2 domain
93 SMARCAD1interactor160.29240.667CUE (PF02845, IPR003892, SM00546): CUE domain
Pox_D5 (PF03288, IPR004968): Poxvirus D5 protein-like
SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
94 SMURF2protein found in more fusions70.9330.400C2 (PF00168, IPR000008, SM00239): C2 domain
WW (PF00397, IPR001202, SM00456): WW domain
HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
95 SNU13interactor80.5714.538Ribosomal_L7Ae (PF01248, IPR004038): Ribosomal protein L7Ae/L30e/S12e/Gadd45 family
96 SP1protein found in more fusions290.339119.626zf-Di19 (PF05605, IPR008598): Drought induced 19 protein (Di19), zinc-binding
Herpes_capsid (PF06112, IPR009299): Gammaherpesvirus capsid protein
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
Miga (PF10265, IPR019392): Mitoguardin
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
97 SP3interactor90.7502.989K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
98 SPRY1interactor40.5002.400PAP1 (PF08601, IPR013910): Transcription factor PAP1
Sprouty (PF05210, IPR007875): Sprouty protein (Spry)
99 SREBF1interactor60.8000.450HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
GIT_CC (PF16559, IPR032352): GIT coiled-coil Rho guanine nucleotide exchange factor
100 SUZ12suppressor210.38459.753DUF2070 (PF09843, IPR019204): Predicted membrane protein (DUF2070)
VEFS-Box (PF09733, IPR019135): VEFS-Box of polycomb protein
101 TCF3suppressor110.53310.141CDC45 (PF02724, IPR003874): CDC45-like protein
HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
DUF3682 (PF12446, IPR022152): Protein of unknown function (DUF3682)
102 TERF1interactor100.5284.808TRF (PF08558, IPR013867): Telomere repeat binding factor (TRF)
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
103 TERF2interactor150.36329.042Aconitase_C (PF00694, IPR000573): Aconitase C-terminal domain
TRF (PF08558, IPR013867): Telomere repeat binding factor (TRF)
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
TERF2_RBM (PF16772, IPR031902): Telomeric repeat-binding factor 2 Rap1-binding motif
104 TESK1interactor21.0000Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
105 TFAP2Asuppressor140.46219.760TF_AP-2 (PF03299, IPR013854): Transcription factor AP-2
CYYR1 (PF10873, IPR022640): Cysteine and tyrosine-rich protein 1
Peptidase_Prp (PF04327): Cysteine protease Prp
106 TFCP2interactor50.7001.833CP2 (PF04516, IPR007604): CP2 transcription factor
DUF2967 (PF11179, IPR021349): Protein of unknown function (DUF2967)
107 TFPToncoprotein160.8955.186GIT_CC (PF16559, IPR032352): GIT coiled-coil Rho guanine nucleotide exchange factor
108 TMEM150Ainteractor100Frag1 (PF10277, IPR019402): Frag1/DRAM/Sfk1 family
109 TP53suppressor450.247399.368DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region
P53 (PF00870, IPR011615): P53 DNA-binding domain
P53_tetramer (PF07710, IPR010991): P53 tetramerisation motif
110 TRPV5interactor21.0000Ank (PF00023, IPR002110, SM00248): Ankyrin repeat
Ion_trans (PF00520, IPR005821): Ion transport protein
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
Ank_4 (PF13637): Ankyrin repeats (many copies)
111 TWIST1oncoprotein100.5338.518ACC_epsilon (PF13822, IPR032716): Acyl-CoA carboxylase epsilon subunit
PRR20 (PF15708, IPR031439): Proline-rich protein family 20
FXR_C1 (PF16096, IPR032172): Fragile X-related 1 protein C-terminal region 2
112 UCHL5oncoprotein200.59152.445Peptidase_C12 (PF01088, IPR001578): Ubiquitin carboxyl-terminal hydrolase, family 1
113 UHRF2suppressor90.5715.330PHD (PF00628, IPR019787, SM00249): PHD-finger
SAD_SRA (PF02182, IPR003105, SM00466): SAD/SRA domain
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
TTD (PF12148, IPR021991): Tandem tudor domain within UHRF1
zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
UBA2_C (PF16195, IPR032426): SUMO-activating enzyme subunit 2 C-terminus
114 WDHD1interactor21.0000PVL_ORF50 (PF07768, IPR011688): PVL ORF-50-like family
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
HMG_box (PF00505, IPR009071, SM00398): HMG (high mobility group) box
Mcl1_mid (PF12341, IPR022100): Minichromosome loss protein, Mcl1, middle region
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
Ge1_WD40 (PF16529, IPR032401): WD40 region of Ge1, enhancer of mRNA-decapping protein
115 XRCC5suppressor190.35941.992Ku (PF02735, IPR006164, SM00559): Ku70/Ku80 beta-barrel domain
Ku_C (PF03730, IPR005160): Ku70/Ku80 C-terminal arm
Ku_N (PF03731, IPR005161): Ku70/Ku80 N-terminal alpha/beta domain
Ku_PK_bind (PF08785, IPR014893): Ku C terminal domain like
116 XRCC6oncoprotein230.39059.865Ku (PF02735, IPR006164, SM00559): Ku70/Ku80 beta-barrel domain
Ku_C (PF03730, IPR005160): Ku70/Ku80 C-terminal arm
Ku_N (PF03731, IPR005161): Ku70/Ku80 N-terminal alpha/beta domain
SAP (PF02037, IPR003034, SM00513): SAP domain
117 YAF2interactor70.5714.825DUF460 (PF04312, IPR007408): Protein of unknown function (DUF460)
OAD_gamma (PF04277, IPR005899): Oxaloacetate decarboxylase, gamma chain
Exo5 (PF09810, IPR019190): Exonuclease V - a 5' deoxyribonuclease
zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others
MPDZ_u10 (PF16667, IPR032078): Unstructured region 10 on multiple PDZ protein
YAF2_RYBP (PF17219): Yaf2/RYBP C-terminal binding motif
118 ZNF232interactor100SCAN (PF02023, IPR003309, SM00431): SCAN domain
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
119 ZNF24interactor30.6670.182SCAN (PF02023, IPR003309, SM00431): SCAN domain
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
120 ZNF638interactor60.8670.500RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
zf-C2H2_jaz (PF12171, IPR022755): Zinc-finger double-stranded RNA-binding
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
zf-met (PF12874): Zinc-finger of C2H2 type
Ferlin_C (PF16165, IPR032362): Ferlin C-terminus
121 ZNF830interactor21.0000Sec34 (PF04136, IPR007265): Sec34-like family
zf-C2H2_jaz (PF12171, IPR022755): Zinc-finger double-stranded RNA-binding

B a c k    t o    T o p ⇑


List of missing interactors (in fusions)

# Name Type Domains (Pfam, InterPro, SMART): description Fusion(s)
1 YY1parental proteinzf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger
Keratin_2_tail (PF16210, IPR032449): Keratin type II cytoskeletal 1 tail
BM924295

B a c k    t o    T o p ⇑