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Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

Powered by Cytoscape Web for: parental proteins YWHAZ (from a repository: Wed Nov 16 23:49:44 2016)
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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)335
The number (and %) of the onco-proteins110 (32.84 %)
The number (and %) of the tumor suppressors50 (14.93 %)
Total number of binary PPIs (saturation %)3219 (5.75 %)
The number (and %) of affected PPIs335 (10.41 %)
The number of possible different fusions72
PPI diameter2
PPI radius1
The average degree of PPI18.418
Assortativity coefficient-0.2395
The network average Clustering coefficient0.486
The number (and %) of a zero Clustering coefficients16 (4.78 %)
The number (and %) of a zero Betweenness Centrality46 (13.73 %)

ACTIVE INTERACTORS


List of the fusions

PPI for parental proteins: YWHAZ All fusions
Proteins found in more fusions GRK5 (see 3 fusions); U2AF2 (see 2 fusions); NPM1 (see 1 fusions); CUL1 (see 3 fusions); COPB1 (see 2 fusions); GRB2 (see 1 fusions); SLC9A3R1 (see 2 fusions); YWHAH (see 2 fusions); MDM4 (see 2 fusions); OPTN (see 1 fusions); EWSR1 (see 2 fusions); PIAS1 (see 2 fusions); YWHAZ (see 1 fusions); SORBS2 (see 4 fusions); MARK3 (see 1 fusions); RAB11FIP2 (see 1 fusions); HDAC5 (see 1 fusions); EP300 (see 1 fusions); MAP3K5 (see 1 fusions); FAN1 (see 1 fusions); HSPB1/OBSL1 (see 1 fusions); APP (see 4 fusions); VCP (see 4 fusions); PRMT5 (see 2 fusions); HUWE1 (see 2 fusions); HDAC4 (see 1 fusions); MARK2 (see 2 fusions); PAK4 (see 1 fusions); NEDD4L (see 3 fusions); BAG3 (see 4 fusions); KAT8 (see 1 fusions); HSPB1 (see 3 fusions); ECHS1 (see 1 fusions); ZAK (see 2 fusions); TGM2 (see 4 fusions); ATP5A1 (see 1 fusions); PRKCE (see 3 fusions); ERRFI1 (see 1 fusions); TUBG1 (see 1 fusions); PPFIBP1 (see 1 fusions); STAU1 (see 2 fusions); MAP3K2 (see 2 fusions); CBL (see 1 fusions); HDAC7 (see 1 fusions); CUL7 (see 2 fusions); PRKCD (see 2 fusions); CUL3 (see 1 fusions); MAPRE1 (see 1 fusions); KIF11 (see 1 fusions); VCL (see 2 fusions); COPS5 (see 1 fusions); FN1/YWHAG (see 1 fusions); PAK2 (see 2 fusions); UBC (see 1 fusions); LRRK2 (see 1 fusions); MTOR (see 1 fusions); LIMK1 (see 1 fusions); TP53 (see 3 fusions); TAB2 (see 1 fusions); YWHAG (see 1 fusions); FOXO1 (see 1 fusions); SQSTM1 (see 5 fusions); SGK1 (see 2 fusions); ATP5A1/HUWE1 (see 2 fusions); HNRNPL (see 2 fusions); MAPT (see 1 fusions); EDC3 (see 1 fusions); EGFR (see 2 fusions); MCM2 (see 1 fusions); BRAF (see 3 fusions); G6PD (see 3 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 YWHAZparental protein3350.04963934.84614-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
2 AANATinteractor100Acetyltransf_1 (PF00583, IPR000182): Acetyltransferase (GNAT) family
3 ABL1oncoprotein320.38584.518Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
SH2 (PF00017, IPR000980, SM00252): SH2 domain
F_actin_bind (PF08919, IPR015015, SM00808): F-actin binding
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
FRG2 (PF15315, IPR026245): Facioscapulohumeral muscular dystrophy candidate 2
4 ADORA3interactor21.00007tm_1 (PF00001, IPR000276): 7 transmembrane receptor (rhodopsin family)
5 AJUBAoncoprotein70.4295.029LIM (PF00412, IPR001781, SM00132): LIM domain
6 AKT1oncoprotein410.208270.554PH (PF00169, IPR001849, SM00233): PH domain
Pkinase (PF00069, IPR000719): Protein kinase domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
7 AKT1S1interactor100.4446.143Pap_E4 (PF02711, IPR003861): E4 protein
PRAS (PF15798, IPR026682): Proline-rich AKT1 substrate 1
8 AP3B1interactor70.3333.419Adaptin_N (PF01602, IPR002553): Adaptin N terminal region
AP3B1_C (PF14796, IPR029390): Clathrin-adaptor complex-3 beta-1 subunit C-terminal
SEEEED (PF14797, IPR029394): Serine-rich region of AP3B1, clathrin-adaptor complex
9 APPprotein found in more fusions720.0961458.099APP_N (PF02177, IPR015849, SM00006): Amyloid A4 N-terminal heparin-binding
Beta-APP (PF03494, IPR013803): Beta-amyloid peptide (beta-APP)
BUD22 (PF09073, IPR015158): BUD22
IncA (PF04156, IPR007285): IncA protein
Kunitz_BPTI (PF00014, IPR002223, SM00131): Kunitz/Bovine pancreatic trypsin inhibitor domain
APP_amyloid (PF10515, IPR019543): beta-amyloid precursor protein C-terminus
APP_Cu_bd (PF12924, IPR011178): Copper-binding of amyloid precursor, CuBD
APP_E2 (PF12925, IPR024329): E2 domain of amyloid precursor protein
10 ARAFoncoprotein150.56216.886Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
RBD (PF02196, IPR003116, SM00455): Raf-like Ras-binding domain
C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain)
11 ARHGEF2oncoprotein150.49512.858IncA (PF04156, IPR007285): IncA protein
PH (PF00169, IPR001849, SM00233): PH domain
RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain
C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain)
12 ARRB1interactor270.30898.105Arrestin_C (PF02752, IPR011022, SM01017): Arrestin (or S-antigen), C-terminal domain
Arrestin_N (PF00339, IPR011021): Arrestin (or S-antigen), N-terminal domain
13 ATG9Ainteractor31.0000APG9 (PF04109, IPR007241): Autophagy protein Apg9
PRRSV_2b (PF07069, IPR009775): Porcine reproductive and respiratory syndrome virus 2b
14 ATP5A1protein found in more fusions350.43163.344ATP-synt_ab (PF00006, IPR000194): ATP synthase alpha/beta family, nucleotide-binding domain
ATP-synt_ab_C (PF00306, IPR000793): ATP synthase alpha/beta chain, C terminal domain
ATP-synt_ab_N (PF02874, IPR004100): ATP synthase alpha/beta family, beta-barrel domain
15 B4GALT7interactor100Glyco_transf_7C (PF02709, IPR027791): N-terminal domain of galactosyltransferase
Glyco_transf_7N (PF13733, IPR027995): N-terminal region of glycosyl transferase group 7
16 BADoncoprotein200.38954.740Bcl-2_BAD (PF10514, IPR018868): Pro-apoptotic Bcl-2 protein, BAD
17 BAG3oncoprotein290.249137.683BAG (PF02179, IPR003103, SM00264): BAG domain
WW (PF00397, IPR001202, SM00456): WW domain
18 BARD1suppressor220.31059.045BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
Ank_5 (PF13857): Ankyrin repeats (many copies)
zf-RING_6 (PF14835): zf-RING of BARD1-type protein
BRCT_2 (PF16589, IPR001357): BRCT domain, a BRCA1 C-terminus domain
19 BCAR1oncoprotein90.5289.283Serine_rich (PF08824, IPR014928): Serine rich protein interaction domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
DUF3513 (PF12026, IPR021901): Domain of unknown function (DUF3513)
Caskin1-CID (PF16600): Caskin1 CASK-interaction domain
20 BDP1interactor100SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal
Eapp_C (PF10238, IPR019370): E2F-associated phosphoprotein
DUF2917 (PF11142, IPR021317): Protein of unknown function (DUF2917)
UPF0542 (PF15086, IPR027877): Uncharacterised protein family UPF0542
Myb_DNA-bind_7 (PF15963): Myb DNA-binding like
21 BRAFoncoprotein170.58318.226Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
RBD (PF02196, IPR003116, SM00455): Raf-like Ras-binding domain
C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain)
22 BRCA1suppressor350.251185.981BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain
zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger)
BRCT_assoc (PF12820, IPR025994): Serine-rich domain associated with BRCT
23 BRD4oncoprotein80.6433.737Caldesmon (PF02029, IPR006018): Caldesmon
Pex14_N (PF04695, IPR006785): Peroxisomal membrane anchor protein (Pex14p) conserved region
Stm1_N (PF09598, IPR019084): Stm1
SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein
Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
NAM-associated (PF14303, IPR029466): No apical meristem-associated C-terminal domain
BET (PF17035, IPR027353): Bromodomain extra-terminal - transcription regulation
BRD4_CDT (PF17105, IPR031354): C-terminal domain of bromodomain protein 4
24 BTRConcoprotein300.298111.770WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Beta-TrCP_D (PF12125, IPR021977, SM01028): D domain of beta-TrCP
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
F-box-like (PF12937, IPR001810): F-box-like
25 CAPNS1interactor140.51611.753EF-hand_1 (PF00036, IPR002048, SM00054): EF hand
EF-hand_6 (PF13405, IPR002048): EF-hand domain
EF-hand_8 (PF13833, IPR002048): EF-hand domain pair
26 CBLsuppressor280.36280.205Cbl_N (PF02262, IPR003153): CBL proto-oncogene N-terminal domain 1
Cbl_N2 (PF02761, IPR014741): CBL proto-oncogene N-terminus, EF hand-like domain
Cbl_N3 (PF02762, IPR014742): CBL proto-oncogene N-terminus, SH2-like domain
UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
Prok-RING_4 (PF14447): Prokaryotic RING finger family 4
zf-RING_4 (PF14570): RING/Ubox like zinc-binding domain
27 CBX4oncoprotein80.6192.552Chromo (PF00385, IPR023780, SM00298): Chromo (CHRromatin Organisation MOdifier) domain
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
SelP_N (PF04592, IPR007671): Selenoprotein P, N terminal region
CBX7_C (PF17218): CBX family C-terminal motif
28 CCDC84interactor100CCDC84 (PF14968, IPR028015): Coiled coil protein 84
29 CDC25Aoncoprotein160.52511.662M-inducer_phosp (PF06617, IPR000751): M-phase inducer phosphatase
Rhodanese (PF00581, IPR001763, SM00450): Rhodanese-like domain
30 CDC25Boncoprotein130.5778.265M-inducer_phosp (PF06617, IPR000751): M-phase inducer phosphatase
Rhodanese (PF00581, IPR001763, SM00450): Rhodanese-like domain
31 CDC25Concoprotein110.6553.654M-inducer_phosp (PF06617, IPR000751): M-phase inducer phosphatase
Rhodanese (PF00581, IPR001763, SM00450): Rhodanese-like domain
32 CDC5Linteractor460.252337.259OmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like)
Pox_A_type_inc (PF04508, IPR007596): Viral A-type inclusion protein repeat
Cir_N (PF10197, IPR019339, SM01083): N-terminal domain of CBF1 interacting co-repressor CIR
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
Myb_Cef (PF11831, IPR021786): pre-mRNA splicing factor component
Myb_DNA-bind_6 (PF13921): Myb-like DNA-binding domain
33 CDCA7interactor50.6000.346zf-C4_ClpX (PF06689, IPR010603, SM00994): ClpX C4-type zinc finger
zf-4CXXC_R1 (PF10497, IPR018866): Zinc-finger domain of monoamine-oxidase A repressor R1
Imm51 (PF15595, IPR028956): Immunity protein 51
34 CDK11Boncoprotein90.7142.660DDHD (PF02862, IPR004177, SM01127): DDHD domain
DivIC (PF04977, IPR007060): Septum formation initiator
Pkinase (PF00069, IPR000719): Protein kinase domain
DUF4748 (PF15932, IPR031833): Domain of unknown function (DUF4748)
35 CDK16oncoprotein100.6441.948Pkinase (PF00069, IPR000719): Protein kinase domain
36 CDK2suppressor540.235425.854Kdo (PF06293, IPR010440): Lipopolysaccharide kinase (Kdo/WaaP) family
Pkinase (PF00069, IPR000719): Protein kinase domain
37 CDKN1Bsuppressor200.39537.528CDI (PF02234, IPR003175): Cyclin-dependent kinase inhibitor
Multi-haem_cyto (PF13447): Seven times multi-haem cytochrome CxxCH
38 CENPJinteractor160.26745.489DASH_Hsk3 (PF08227, IPR013183): DASH complex subunit Hsk3 like
DUF1795 (PF08786, IPR014894): Domain of unknown function (DUF1795)
DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972)
Rota_VP2 (PF05087, IPR007779): Rotavirus VP2 protein
Tcp10_C (PF07202, IPR009852): T-complex protein 10 C-terminus
TSC22 (PF01166, IPR000580): TSC-22/dip/bun family
AAA_23 (PF13476): AAA domain
DUF4140 (PF13600, IPR025554): N-terminal domain of unknown function (DUF4140)
39 CEP126interactor21.0000Nop25 (PF09805, IPR019186): Nucleolar protein 12 (25kDa)
K1377 (PF15352, IPR028257): Susceptibility to monomelic amyotrophy
40 CGNL1interactor31.0000Abhydrolase_4 (PF08386, IPR013595): TAP-like protein
Myosin_tail_1 (PF01576, IPR002928): Myosin tail
41 CHAF1Ainteractor120.4557.038CAF-1_p150 (PF11600): Chromatin assembly factor 1 complex p150 subunit, N-terminal
CAF1A (PF12253, IPR022043): Chromatin assembly factor 1 subunit A
CAF1-p150_C2 (PF15539, IPR029105): CAF1 complex subunit p150, region binding to CAF1-p60 at C-term
CAF1-p150_N (PF15557, IPR029091): CAF1 complex subunit p150, region binding to PCNA
42 CLK3interactor110.3566.662Pkinase (PF00069, IPR000719): Protein kinase domain
SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein
43 COPB1protein found in more fusions200.40421.199Adaptin_N (PF01602, IPR002553): Adaptin N terminal region
Coatamer_beta_C (PF07718, IPR011710): Coatomer beta C-terminal region
Coatomer_b_Cpla (PF14806, IPR029446): Coatomer beta subunit appendage platform
44 COPS5protein found in more fusions570.253433.755JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease
45 COPS7Binteractor110.6007.963PCI (PF01399, IPR000717, SM00088): PCI domain
46 CRY1interactor180.43417.003DNA_photolyase (PF00875, IPR006050): DNA photolyase
FAD_binding_7 (PF03441, IPR005101): FAD binding domain of DNA photolyase
47 CSF2RBinteractor200fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
IL4Ra_N (PF09238, IPR015319): Interleukin-4 receptor alpha chain, N-terminal
IL6Ra-bind (PF09240, IPR015321): Interleukin-6 receptor alpha chain, binding
Tissue_fac (PF01108, IPR003961): Tissue factor
48 CSNK1Dinteractor90.33310.638Pkinase (PF00069, IPR000719): Protein kinase domain
49 CTNNB1oncoprotein400.249202.920Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
Atx10homo_assoc (PF09759, IPR019156): Spinocerebellar ataxia type 10 protein domain
DUF3361 (PF11841, IPR024574): Domain of unknown function (DUF3361)
HEAT_EZ (PF13513): HEAT-like repeat
50 CUL1suppressor480.302220.433Cullin (PF00888, IPR001373, SM00182): Cullin family
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
51 CUL2suppressor350.303133.673Cullin (PF00888, IPR001373, SM00182): Cullin family
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
52 CUL3protein found in more fusions640.249557.774Cullin (PF00888, IPR001373, SM00182): Cullin family
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
WAC_Acf1_DNA_bd (PF10537, IPR013136): ATP-utilising chromatin assembly and remodelling N-terminal
53 CUL7protein found in more fusions430.292188.860ANAPC10 (PF03256, IPR004939): Anaphase-promoting complex, subunit 10 (APC10)
Cullin (PF00888, IPR001373, SM00182): Cullin family
DUF1918 (PF08940, IPR015035): Domain of unknown function (DUF1918)
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
Cul7 (PF11515, IPR021097): Mouse development and cellular proliferation protein Cullin-7
54 CWC27interactor21.0000Pro_isomerase (PF00160, IPR002130): Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD
DUF4407 (PF14362, IPR025519): Domain of unknown function (DUF4407)
55 CYFIP1interactor50.6001.225DUF1394 (PF07159, IPR009828): Protein of unknown function (DUF1394)
FragX_IP (PF05994, IPR008081): Cytoplasmic Fragile-X interacting family
56 CYFIP2interactor80.6073.467DUF1394 (PF07159, IPR009828): Protein of unknown function (DUF1394)
FragX_IP (PF05994, IPR008081): Cytoplasmic Fragile-X interacting family
zf-CW (PF07496, IPR011124): CW-type Zinc Finger
57 DCAF7interactor140.49512.700WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
58 DDIT4interactor40.6670.237RTP801_C (PF07809, IPR012918): RTP801 C-terminal region
59 DFFAsuppressor120.4559.796CIDE-N (PF02017, IPR003508): CIDE-N domain
DFF-C (PF09033, IPR015121): DNA Fragmentation factor 45kDa, C terminal domain
T2SSppdC (PF12528, IPR022204): Type II secretion prepilin peptidase dependent protein C
SAPIS-gp6 (PF16722, IPR031999): Pathogenicity island protein gp6 in Staphylococcus
60 DISC1interactor80.6436.509HALZ (PF02183, IPR003106, SM00340): Homeobox associated leucine zipper
Mnd1 (PF03962, IPR005647): Mnd1 family
TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein
Tropomyosin (PF00261, IPR000533): Tropomyosin
UVR (PF02151, IPR001943): UvrB/uvrC motif
CENP-F_leu_zip (PF10473, IPR019513): Leucine-rich repeats of kinetochore protein Cenp-F/LEK1
bZIP_2 (PF07716, IPR004827, SM00338): Basic region leucine zipper
ADIP (PF11559, IPR021622): Afadin- and alpha -actinin-Binding
61 DMTNinteractor80.4642.866VHP (PF02209, IPR003128, SM00153): Villin headpiece domain
AbLIM_anchor (PF16182, IPR032402): Putative adherens-junction anchoring region of AbLIM
62 DNAJB4suppressor60.6001.462DnaJ (PF00226, IPR001623, SM00271): DnaJ domain
DnaJ_C (PF01556, IPR002939): DnaJ C terminal domain
63 DOCK7interactor160.40019.359DHR-2 (PF06920, IPR010703): Dock homology region 2
DUF3398 (PF11878, IPR021816): Domain of unknown function (DUF3398)
DOCK-C2 (PF14429, IPR027007): C2 domain in Dock180 and Zizimin proteins
DOCK_N (PF16172, IPR032376): DOCK N-terminus
64 DTLinteractor100.6002.354WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
65 ECHS1protein found in more fusions140.38518.230ECH_1 (PF00378, IPR001753): Enoyl-CoA hydratase/isomerase
66 ECT2suppressor110.32715.836BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain
RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain
PTCB-BRCT (PF12738, IPR001357): twin BRCT domain
PGBA_C (PF15437, IPR032737): Plasminogen-binding protein pgbA C-terminal
67 EDC3protein found in more fusions70.8670.096FDF (PF09532, IPR019050, SM01199): FDF domain
YjeF_N (PF03853, IPR004443): YjeF-related protein N-terminus
LSM14 (PF12701, IPR025609): Scd6-like Sm domain
Edc3_linker (PF16598): Linker region of enhancer of mRNA-decapping protein 3
DUF5096 (PF17019, IPR031512): Domain of unknown function (DUF5096)
68 EFNB3interactor100Ephrin (PF00812, IPR001799): Ephrin
69 EGFRoncoprotein560.193590.944Furin-like (PF00757, IPR006211): Furin-like cysteine rich region
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
Recep_L_domain (PF01030, IPR000494): Receptor L domain
GAPT (PF11770, IPR021082): GRB2-binding adapter (GAPT)
GF_recep_IV (PF14843, IPR032778): Growth factor receptor domain IV
70 EIF3Aoncoprotein180.32030.419DUF1003 (PF06210, IPR010406): Protein of unknown function (DUF1003)
Ly49 (PF08391, IPR013600): Ly49-like protein, N-terminal region
PCI (PF01399, IPR000717, SM00088): PCI domain
AIM3 (PF17096, IPR031370): Altered inheritance of mitochondria protein 3
71 EIF4Binteractor150.48411.102RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
DUF3774 (PF12609, IPR022251): Wound-induced protein
PROL5-SMR (PF15621, IPR026288): Proline-rich submaxillary gland androgen-regulated family
72 EIF5interactor180.59515.336CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
Hist_rich_Ca-bd (PF10529, IPR019552): Histidine-rich Calcium-binding repeat region
eIF-5_eIF-2B (PF01873, IPR002735, SM00653): Domain found in IF2B/IF5
W2 (PF02020, IPR003307, SM00515): eIF4-gamma/eIF5/eIF2-epsilon
73 ENO1oncoprotein390.294184.460Enolase_C (PF00113, IPR020810): Enolase, C-terminal TIM barrel domain
Enolase_N (PF03952, IPR020811): Enolase, N-terminal domain
74 EP300oncoprotein420.174390.887Creb_binding (PF09030, IPR014744): Creb binding
DUF902 (PF06001, IPR010303): Domain of Unknown Function (DUF902)
Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region
KIX (PF02172, IPR003101): KIX domain
RR_TM4-6 (PF06459, IPR009460): Ryanodine Receptor TM 4-6
TPX2 (PF06886, IPR027329): Targeting protein for Xklp2 (TPX2)
zf-TAZ (PF02135, IPR000197, SM00551): TAZ zinc finger
HAT_KAT11 (PF08214, IPR013178): Histone acetylation protein
Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type
75 EPB41L2interactor70.7141.3784_1_CTD (PF05902, IPR008379): 4.1 protein C-terminal domain (CTD)
Asp-B-Hydro_N (PF05279, IPR007943): Aspartyl beta-hydroxylase N-terminal region
DUF966 (PF06136, IPR010369): Domain of unknown function (DUF966)
FA (PF08736, IPR014847): FERM adjacent (FA)
FERM_C (PF09380, IPR018980): FERM C-terminal PH-like domain
FERM_M (PF00373, IPR019748): FERM central domain
FERM_N (PF09379, IPR018979): FERM N-terminal domain
SAB (PF04382, IPR007477): SAB domain
TCP (PF03634, IPR005333): TCP family transcription factor
76 EPB41L3suppressor150.46729.2744_1_CTD (PF05902, IPR008379): 4.1 protein C-terminal domain (CTD)
FA (PF08736, IPR014847): FERM adjacent (FA)
FERM_C (PF09380, IPR018980): FERM C-terminal PH-like domain
FERM_M (PF00373, IPR019748): FERM central domain
FERM_N (PF09379, IPR018979): FERM N-terminal domain
RNA_pol_Rpc4 (PF05132, IPR007811): RNA polymerase III RPC4
SAB (PF04382, IPR007477): SAB domain
77 ERP44interactor140.38527.672Thioredoxin (PF00085, IPR013766): Thioredoxin
Thioredoxin_6 (PF13848): Thioredoxin-like domain
78 ERRFI1suppressor100.6117.697GTPase_binding (PF09027, IPR015116): GTPase binding
Inhibitor_Mig-6 (PF11555, IPR021619): EGFR receptor inhibitor Mig-6
79 EWSR1oncoprotein430.245296.132RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
SVS_QK (PF10578, IPR018942): Seminal vesicle protein repeat
zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
Keratin_2_head (PF16208, IPR032444): Keratin type II head
80 EXO1interactor70.8570.130XPG_I (PF00867, IPR006086, SM00484): XPG I-region
XPG_N (PF00752, IPR006085, SM00485): XPG N-terminal domain
81 FAM13Binteractor41.0000COG2 (PF06148, IPR024602): COG (conserved oligomeric Golgi) complex component, COG2
MazG (PF03819, IPR004518): MazG nucleotide pyrophosphohydrolase domain
RhoGAP (PF00620, IPR000198, SM00324): RhoGAP domain
Drc1-Sld2 (PF11719, IPR021110): DNA replication and checkpoint protein
GOLD_2 (PF13897, IPR009038): Golgi-dynamics membrane-trafficking
82 FAM189A2interactor80.5005.948CD20 (PF04103, IPR007237): CD20-like family
83 FAM53Cinteractor50.8000.128FAM53 (PF15242, IPR029356): Family of FAM53
84 FAM65Binteractor30.6670.167Glu-tRNAGln (PF02686, IPR003837): Glu-tRNAGln amidotransferase C subunit
HEAT_2 (PF13646): HEAT repeats
PL48 (PF15903, IPR031780): Filopodia upregulated, FAM65
85 FAN1protein found in more fusions40.6670.056VRR_NUC (PF08774, IPR014883, SM00990): VRR-NUC domain
zf-TRAF (PF02176, IPR001293): TRAF-type zinc finger
TPR_12 (PF13424): Tetratricopeptide repeat
DUF4363 (PF14276, IPR025373): Domain of unknown function (DUF4363)
86 FBXO6interactor350.254154.253FBA (PF04300, IPR007397): F-box associated region
F-box-like (PF12937, IPR001810): F-box-like
87 FBXW11interactor370.259185.626WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Beta-TrCP_D (PF12125, IPR021977, SM01028): D domain of beta-TrCP
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
F-box-like (PF12937, IPR001810): F-box-like
88 FERMT2interactor170.44926.740FERM_M (PF00373, IPR019748): FERM central domain
FERM_N (PF09379, IPR018979): FERM N-terminal domain
89 FHOD1interactor70.7330.939Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator
FH2 (PF02181, IPR015425, SM00498): Formin Homology 2 Domain
90 FN1oncoprotein490.269253.733fn1 (PF00039, IPR000083, SM00058): Fibronectin type I domain
fn2 (PF00040, IPR000562, SM00059): Fibronectin type II domain
fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369)
91 FOXO1suppressor90.4644.475K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain
Forkhead (PF00250, IPR001766, SM00339): Forkhead domain
FOXO_KIX_bdg (PF16675, IPR032068): KIX-binding domain of forkhead box O, CR2
FOXO-TAD (PF16676, IPR032067): Transactivation domain of FOXO protein family
92 FOXO3suppressor160.44217.900Lin-8 (PF03353, IPR005020): Ras-mediated vulval-induction antagonist
Forkhead (PF00250, IPR001766, SM00339): Forkhead domain
FOXO_KIX_bdg (PF16675, IPR032068): KIX-binding domain of forkhead box O, CR2
FOXO-TAD (PF16676, IPR032067): Transactivation domain of FOXO protein family
93 FUSsuppressor370.428102.356Herpes_PAP (PF03325, IPR004997): Herpesvirus polymerase accessory protein
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
SVS_QK (PF10578, IPR018942): Seminal vesicle protein repeat
zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others
Limkain-b1 (PF11608, IPR024582): Limkain b1
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
Keratin_2_head (PF16208, IPR032444): Keratin type II head
94 G6PDprotein found in more fusions240.52240.889G6PD_C (PF02781, IPR022675): Glucose-6-phosphate dehydrogenase, C-terminal domain
G6PD_N (PF00479, IPR022674): Glucose-6-phosphate dehydrogenase, NAD binding domain
95 GABARAPL2interactor120.28823.167Atg8 (PF02991, IPR004241): Autophagy protein Atg8 ubiquitin like
96 GCH1interactor31.0000GTP_cyclohydroI (PF01227, IPR020602): GTP cyclohydrolase I
97 GINS4interactor30.6670.400Sld5 (PF05916, IPR021151): GINS complex protein
SLD5_C (PF16922, IPR031633): DNA replication complex GINS protein SLD5 C-terminus
98 GP1BAinteractor100LRRNT (PF01462, IPR000372, SM00013): Leucine rich repeat N-terminal domain
LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies)
LRR_8 (PF13855, IPR001611): Leucine rich repeat
99 GP1BBinteractor100CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
100 GRB2oncoprotein470.277345.748SH2 (PF00017, IPR000980, SM00252): SH2 domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
DUF5093 (PF17011, IPR031533): Domain of unknown function (DUF5093)
101 GRK5protein found in more fusions190.24264.540Pkinase (PF00069, IPR000719): Protein kinase domain
RGS (PF00615, IPR000342, SM00315): Regulator of G protein signaling domain
102 H2AFXsuppressor250.40358.321Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
Histone_H2A_C (PF16211, IPR032454): C-terminus of histone H2A
103 HDAC4oncoprotein190.45137.361Borrelia_P83 (PF05262, IPR007926): Borrelia P83/100 protein
Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
HDAC4_Gln (PF12203, IPR024643): Glutamine rich N terminal domain of histone deacetylase 4
104 HDAC5protein found in more fusions430.274245.311Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
NOA36 (PF06524, IPR010531): NOA36 protein
Activator_LAG-3 (PF11498, IPR021587): Transcriptional activator LAG-3
HDAC4_Gln (PF12203, IPR024643): Glutamine rich N terminal domain of histone deacetylase 4
105 HDAC6oncoprotein260.29389.037Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
PSGP (PF07276, IPR009900): Apopolysialoglycoprotein (PSGP)
zf-UBP (PF02148, IPR001607, SM00290): Zn-finger in ubiquitin-hydrolases and other protein
106 HDAC7protein found in more fusions200.43332.713Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
PRIMA1 (PF16101): Proline-rich membrane anchor 1
CBP_BcsO (PF17037, IPR031484): Cellulose biosynthesis protein BcsO
107 HDAC9interactor90.5364.207Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
SAE2 (PF08573, IPR013882): DNA repair protein endonuclease SAE2/CtIP C-terminus
HDAC4_Gln (PF12203, IPR024643): Glutamine rich N terminal domain of histone deacetylase 4
CEP19 (PF14933, IPR029412): CEP19-like protein
108 HIST1H3Ainteractor270.33892.051Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
109 HIST1H4Ainteractor280.30795.258CENP-T_C (PF15511): Centromere kinetochore component CENP-T histone fold
110 HIVEP2interactor60.8000.363Cwf_Cwc_15 (PF04889, IPR006973): Cwf15/Cwc15 cell cycle control protein
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
111 HMGN1interactor41.0000HMG14_17 (PF01101, IPR000079, SM00527): HMG14 and HMG17
112 HNF1Aoncoprotein80.6670.955HNF-1_N (PF04814, IPR006899): Hepatocyte nuclear factor 1 (HNF-1), N terminus
HNF-1A_C (PF04813, IPR006898): Hepatocyte nuclear factor 1 (HNF-1), alpha isoform C terminus
HNF-1B_C (PF04812, IPR006897): Hepatocyte nuclear factor 1 (HNF-1), beta isoform C terminus
Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
113 HNRNPA1interactor510.337232.650RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
HnRNPA1 (PF11627, IPR021662): Nuclear factor hnRNPA1
114 HNRNPLprotein found in more fusions220.49014.978RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
Dscam_C (PF12355, IPR021012): Down syndrome cell adhesion molecule C terminal
RRM_5 (PF13893): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
115 HS6ST2interactor100Sulfotransfer_2 (PF03567, IPR005331): Sulfotransferase family
Clr2 (PF10383, IPR018839): Transcription-silencing protein Clr2
116 HSPA1Binteractor200.35824.050HSP70 (PF00012, IPR013126): Hsp70 protein
117 HSPB1oncoprotein510.259372.072HSP20 (PF00011, IPR002068): Hsp20/alpha crystallin family
118 HUWE1oncoprotein440.297214.643BUD22 (PF09073, IPR015158): BUD22
DUF908 (PF06012, IPR010309): Domain of Unknown Function (DUF908)
DUF913 (PF06025, IPR010314): Domain of Unknown Function (DUF913)
FdhE (PF04216, IPR006452): Protein involved in formate dehydrogenase formation
HABP4_PAI-RBP1 (PF04774, IPR006861): Hyaluronan / mRNA binding family
Ku_C (PF03730, IPR005160): Ku70/Ku80 C-terminal arm
Merozoite_SPAM (PF07133, IPR010784): Merozoite surface protein (SPAM)
Mucin (PF01456, IPR000458): Mucin-like glycoprotein
Nop14 (PF04147, IPR007276): Nop14-like family
PBP_sp32 (PF07222, IPR009865): Proacrosin binding protein sp32
RNA_pol_Rpc4 (PF05132, IPR007811): RNA polymerase III RPC4
TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
WWE (PF02825, IPR004170, SM00678): WWE domain
HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
Tim54 (PF11711, IPR021056): Inner membrane protein import complex subunit Tim54
U1snRNP70_N (PF12220, IPR022023): U1 small nuclear ribonucleoprotein of 70kDa MW N terminal
DUF4414 (PF14377, IPR025527): Domain of unknown function (DUF4414)
119 IL9Rinteractor100NA
120 ING1suppressor100.6221.676PHD (PF00628, IPR019787, SM00249): PHD-finger
NPR3 (PF03666, IPR005365): Nitrogen Permease regulator of amino acid transport activity 3
ING (PF12998, IPR024610): Inhibitor of growth proteins N-terminal histone-binding
zf-C4pol (PF14260, IPR025687): C4-type zinc-finger of DNA polymerase delta
121 INPP5Ainteractor100Exo_endo_phos (PF03372, IPR005135): Endonuclease/Exonuclease/phosphatase family
Glyco_hydro_cc (PF11790, IPR024655): Glycosyl hydrolase catalytic core
122 IRS2oncoprotein120.7272.003CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
IRS (PF02174, IPR002404, SM00310): PTB domain (IRS-1 type)
PH (PF00169, IPR001849, SM00233): PH domain
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
PRIMA1 (PF16101): Proline-rich membrane anchor 1
123 IRS4interactor200.51618.914CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator
IRS (PF02174, IPR002404, SM00310): PTB domain (IRS-1 type)
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
TAT_signal (PF10518, IPR019546): TAT (twin-arginine translocation) pathway signal sequence
PH_11 (PF15413): Pleckstrin homology domain
124 ISOC1interactor130.7186.115Isochorismatase (PF00857, IPR000868): Isochorismatase family
Glyco_trans_4_4 (PF13579, IPR028098): Glycosyl transferase 4-like domain
125 ITGA4interactor360.37683.147FG-GAP (PF01839, IPR013517): FG-GAP repeat
Integrin_alpha (PF00357, IPR018184): Integrin alpha cytoplasmic region
Integrin_alpha2 (PF08441, IPR013649): Integrin alpha
126 ITGB2interactor70.4294.422EGF_2 (PF07974, IPR013111): EGF-like domain
Integrin_b_cyt (PF08725, IPR014836): Integrin beta cytoplasmic domain
Integrin_B_tail (PF07965, IPR012896): Integrin beta tail domain
Integrin_beta (PF00362, IPR002369, SM00187): Integrin, beta chain
PSI_integrin (PF17205): Integrin plexin domain
127 KAT8protein found in more fusions110.6007.411MOZ_SAS (PF01853, IPR002717): MOZ/SAS family
Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain)
Tudor-knot (PF11717, IPR025995): RNA binding activity-knot of a chromodomain
128 KIAA0232interactor21.0000DUF4603 (PF15376, IPR027871): Domain of unknown function (DUF4603)
129 KIAA0930interactor80.7500.489DUF2045 (PF09741, IPR019141): Uncharacterized conserved protein (DUF2045)
130 KIF11protein found in more fusions140.33328.819Baculo_PEP_C (PF04513, IPR007601): Baculovirus polyhedron envelope protein, PEP, C terminus
COG2 (PF06148, IPR024602): COG (conserved oligomeric Golgi) complex component, COG2
DUF106 (PF01956, IPR002809): Integral membrane protein DUF106
DUF16 (PF01519, IPR002862): Protein of unknown function DUF16
Gag_p17 (PF00540, IPR000071): gag gene protein p17 (matrix protein)
Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein
KxDL (PF10241, IPR019371): Uncharacterized conserved protein
Kinesin (PF00225, IPR001752, SM00129): Kinesin motor domain
DUF3510 (PF12022, IPR024603): Domain of unknown function (DUF3510)
Microtub_bind (PF13931, IPR025901): Kinesin-associated microtubule-binding
131 KIF1Cinteractor80.7142.820FHA (PF00498, IPR000253, SM00240): FHA domain
IncA (PF04156, IPR007285): IncA protein
Kinesin (PF00225, IPR001752, SM00129): Kinesin motor domain
Kinesin_assoc (PF16183, IPR032405): Kinesin-associated
132 KIF23interactor150.39023.083DUF730 (PF05325, IPR007989): Protein of unknown function (DUF730)
Kinesin (PF00225, IPR001752, SM00129): Kinesin motor domain
ADIP (PF11559, IPR021622): Afadin- and alpha -actinin-Binding
TMF_DNA_bd (PF12329, IPR022092): TATA element modulatory factor 1 DNA binding
MKLP1_Arf_bdg (PF16540, IPR032384): Arf6-interacting domain of mitotic kinesin-like protein 1
133 KIF5Binteractor200.44231.513ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16)
Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein
Sec2p (PF06428, IPR009449): GDP/GTP exchange factor Sec2p
Kinesin (PF00225, IPR001752, SM00129): Kinesin motor domain
DUF3584 (PF12128, IPR021979): Protein of unknown function (DUF3584)
HAUS-augmin3 (PF14932, IPR032733): HAUS augmin-like complex subunit 3
DUF4226 (PF10774, IPR019710): Domain of unknown function (DUF4226)
PRKG1_interact (PF15898, IPR031775): cGMP-dependent protein kinase interacting domain
134 KLC1interactor150.44826.394Gly_radical (PF01228, IPR001150): Glycine radical
SOGA (PF11365, IPR027881): Protein SOGA
TPR_10 (PF13374, IPR011990): Tetratricopeptide repeat
TPR_12 (PF13424): Tetratricopeptide repeat
JIP_LZII (PF16471, IPR032486): JNK-interacting protein leucine zipper II
135 KLC4interactor100.7782.542Flagellin_N (PF00669, IPR001029): Bacterial flagellin N-terminal helical region
Uso1_p115_C (PF04871, IPR006955): Uso1 / p115 like vesicle tethering protein, C terminal region
TPR_10 (PF13374, IPR011990): Tetratricopeptide repeat
TPR_12 (PF13424): Tetratricopeptide repeat
LUD_dom (PF02589): LUD domain
136 KLF11interactor30.6671.000zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
137 KLHL7interactor60.9000.053BACK (PF07707, IPR011705, SM00875): BTB And C-terminal Kelch
BTB (PF00651, IPR013069, SM00225): BTB/POZ domain
Kelch_1 (PF01344, IPR006652, SM00612): Kelch motif
Kelch_6 (PF13964): Kelch motif
138 LARP1interactor200.43735.582La (PF05383, IPR006630, SM00715): La domain
Pox_Ag35 (PF03286, IPR004966): Pox virus Ag35 surface protein
FXMRP1_C_core (PF12235, IPR022034): Fragile X-related 1 protein core C terminal
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
139 LCA5interactor110.50912.856IncA (PF04156, IPR007285): IncA protein
Uso1_p115_C (PF04871, IPR006955): Uso1 / p115 like vesicle tethering protein, C terminal region
Tantalus (PF15386, IPR028149): Drosophila Tantalus-like
Lebercilin (PF15619, IPR028933): Ciliary protein causing Leber congenital amaurosis disease
140 LCP2interactor50.8000.389SAM_2 (PF07647, IPR011510): SAM domain (Sterile alpha motif)
SDA1 (PF05285, IPR007949): SDA1
SH2 (PF00017, IPR000980, SM00252): SH2 domain
141 LDHBinteractor300.369106.514Ldh_1_C (PF02866, IPR022383): lactate/malate dehydrogenase, alpha/beta C-terminal domain
Ldh_1_N (PF00056, IPR001236): lactate/malate dehydrogenase, NAD binding domain
142 LIMK1oncoprotein90.3936.779LIM (PF00412, IPR001781, SM00132): LIM domain
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
143 LRMPsuppressor21.0000APG6 (PF04111, IPR007243): Autophagy protein Apg6
MRVI1 (PF05781, IPR008677): MRVI1 protein
DUF2203 (PF09969, IPR018699): Uncharacterized conserved protein (DUF2203)
EF-hand_9 (PF14658): EF-hand domain
KASH_CCD (PF14662, IPR028168): Coiled-coil region of CCDC155 or KASH
Sulfatase_C (PF14707): C-terminal region of aryl-sulfatase
PRKG1_interact (PF15898, IPR031775): cGMP-dependent protein kinase interacting domain
144 LRRK2oncoprotein150.51618.430Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
ATP-synt_ab (PF00006, IPR000194): ATP synthase alpha/beta family, nucleotide-binding domain
DUF1043 (PF06295, IPR009386): Protein of unknown function (DUF1043)
T2SSE (PF00437, IPR001482): Type II/IV secretion system protein
Roc (PF08477, IPR013684): Ras of Complex, Roc, domain of DAPkinase
Pkinase (PF00069, IPR000719): Protein kinase domain
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies)
PQQ_2 (PF13360, IPR002372): PQQ-like domain
LRR_8 (PF13855, IPR001611): Leucine rich repeat
COR (PF16095, IPR032171): C-terminal of Roc, COR, domain
145 LYSTinteractor50.8000.650Beach (PF02138, IPR000409, SM01026): Beige/BEACH domain
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
PH_BEACH (PF14844, IPR023362): PH domain associated with Beige/BEACH
DUF4800 (PF16057): Domain of unknown function (DUF4800)
146 MADDsuppressor60.4673.640DENN (PF02141, IPR001194, SM00799): DENN (AEX-3) domain
HD-ZIP_N (PF04618, IPR006712): HD-ZIP protein N terminus
uDENN (PF03456, IPR005113, SM00800): uDENN domain
147 MAP2K1oncoprotein130.53014.663Pkinase (PF00069, IPR000719): Protein kinase domain
DUF3216 (PF11505, IPR023108): Protein of unknown function (DUF3216)
148 MAP2K5oncoprotein120.36422.264PB1 (PF00564, IPR000270, SM00666): PB1 domain
Pkinase (PF00069, IPR000719): Protein kinase domain
149 MAP3K2protein found in more fusions140.44918.205PB1 (PF00564, IPR000270, SM00666): PB1 domain
Pkinase (PF00069, IPR000719): Protein kinase domain
150 MAP3K4suppressor60.5003.150CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
Pkinase (PF00069, IPR000719): Protein kinase domain
PLU-1 (PF08429, IPR013637): PLU-1-like protein
Radial_spoke_3 (PF06098, IPR009290): Radial spoke protein 3
DUF3682 (PF12446, IPR022152): Protein of unknown function (DUF3682)
DUF3958 (PF13125, IPR025014): Protein of unknown function (DUF3958)
151 MAP3K5oncoprotein110.4677.376Pkinase (PF00069, IPR000719): Protein kinase domain
DUF4071 (PF13281, IPR025136): Domain of unknown function (DUF4071)
152 MAPK7oncoprotein200.39837.444Pkinase (PF00069, IPR000719): Protein kinase domain
Rrn6 (PF10214, IPR019350): RNA polymerase I-specific transcription-initiation factor
153 MAPK8oncoprotein240.209114.600DUF530 (PF04409, IPR007503): Protein of unknown function (DUF530)
Pkinase (PF00069, IPR000719): Protein kinase domain
154 MAPKAPK2oncoprotein110.44410.094Pkinase (PF00069, IPR000719): Protein kinase domain
155 MAPRE1oncoprotein250.27589.705CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
EB1 (PF03271, IPR004953): EB1-like C-terminal motif
SUIM_assoc (PF16619): Unstructured region C-term to UIM in Ataxin3
156 MAPTprotein found in more fusions220.31063.474Tubulin-binding (PF00418, IPR001084): Tau and MAP protein, tubulin-binding repeat
157 MARK1interactor70.6191.431KA1 (PF02149, IPR001772): Kinase associated domain 1
Pkinase (PF00069, IPR000719): Protein kinase domain
UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
158 MARK2protein found in more fusions260.41070.805DUF702 (PF05142, IPR007818): Domain of unknown function (DUF702)
KA1 (PF02149, IPR001772): Kinase associated domain 1
Pkinase (PF00069, IPR000719): Protein kinase domain
UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
159 MARK3protein found in more fusions160.7057.294KA1 (PF02149, IPR001772): Kinase associated domain 1
Pex14_N (PF04695, IPR006785): Peroxisomal membrane anchor protein (Pex14p) conserved region
Pkinase (PF00069, IPR000719): Protein kinase domain
UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
160 MAST1interactor70.6191.479DUF1908 (PF08926, IPR015022): Domain of unknown function (DUF1908)
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
Pkinase (PF00069, IPR000719): Protein kinase domain
161 MCM2oncoprotein560.325300.571AAA_3 (PF07726, IPR011703): ATPase family associated with various cellular activities (AAA)
MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family
MCM2_N (PF12619, IPR008045): Mini-chromosome maintenance protein 2
MCM_N (PF14551, IPR027925): MCM N-terminal domain
MCM_OB (PF17207): MCM OB domain
162 MDC1suppressor190.35754.606FHA (PF00498, IPR000253, SM00240): FHA domain
DUF3274 (PF11678, IPR021692): Protein of unknown function (DUF3274)
Yop-YscD_cpl (PF16697, IPR032030): Inner membrane component of T3SS, cytoplasmic domain
RTT107_BRCT_5 (PF16770, IPR001357): Regulator of Ty1 transposition protein 107 BRCT domain
163 MDM4oncoprotein150.5168.646zf-FLZ (PF04570, IPR007650): zinc-finger of the FCS-type, C2-C2
SWIB (PF02201, IPR003121, SM00151): SWIB/MDM2 domain
zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others
zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
164 MEF2Concoprotein80.3935.756SRF-TF (PF00319, IPR002100, SM00432): SRF-type transcription factor (DNA-binding and dimerisation domain)
HJURP_C (PF12347, IPR022102): Holliday junction regulator protein family C-terminal repeat
165 MEPCEinteractor140.31932.376Bin3 (PF06859, IPR010675): Bicoid-interacting protein 3 (Bin3)
Methyltransf_23 (PF13489): Methyltransferase domain
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
DLEU7 (PF15760, IPR031510): Leukemia-associated protein 7
166 MEX3Binteractor51.0000KH_1 (PF00013, IPR004088, SM00322): KH domain
DUF3446 (PF11928, IPR021849): Domain of unknown function (DUF3446)
zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
IMUP (PF15761, IPR026621): Immortalisation up-regulated protein
167 MGMTinteractor100.5335.160DNA_binding_1 (PF01035, IPR014048): 6-O-methylguanine DNA methyltransferase, DNA binding domain
Methyltransf_1N (PF02870, IPR008332): 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain
168 MOV10interactor480.145447.649AAA_12 (PF13087): AAA domain
AAA_30 (PF13604): AAA domain
169 MPHOSPH9interactor40.8330.182CHDCT2 (PF08074, IPR012957): CHDCT2 (NUC038) domain
FliD_N (PF02465, IPR003481): Flagellar hook-associated protein 2 N-terminus
IL15 (PF02372, IPR003443): Interleukin 15
Tup_N (PF08581, IPR013890): Tup N-terminal
KASH_CCD (PF14662, IPR028168): Coiled-coil region of CCDC155 or KASH
HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1
170 MSL2interactor60.7330.855MSL2-CXC (PF16682, IPR032049): CXC domain of E3 ubiquitin-protein ligase MSL2
zf-RING_10 (PF16685, IPR032043): zinc RING finger of MSL2
171 MST1Rsuppressor100.7781.048Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
PSI (PF01437, IPR002165, SM00423): Plexin repeat
Sema (PF01403, IPR001627, SM00630): Sema domain
TIG (PF01833, IPR002909): IPT/TIG domain
172 MTORoncoprotein230.28668.792DUF1104 (PF06518, IPR009488): Protein of unknown function (DUF1104)
EPSP_synthase (PF00275, IPR001986): EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase)
FAT (PF02259, IPR003151): FAT domain
FATC (PF02260, IPR003152): FATC domain
HEAT (PF02985, IPR000357): HEAT repeat
FRB_dom (PF08771, IPR009076): FKBP12-rapamycin binding domain
V-ATPase_H_N (PF03224, IPR004908): V-ATPase subunit H
PI3_PI4_kinase (PF00454, IPR000403, SM00146): Phosphatidylinositol 3- and 4-kinase
DUF3385 (PF11865, IPR024585): Domain of unknown function (DUF3385)
HEAT_EZ (PF13513): HEAT-like repeat
HEAT_2 (PF13646): HEAT repeats
TPR_19 (PF14559): Tetratricopeptide repeat
173 MYCBP2interactor110.5099.358ANAPC10 (PF03256, IPR004939): Anaphase-promoting complex, subunit 10 (APC10)
Filamin (PF00630, IPR017868): Filamin/ABP280 repeat
Peptidase_S49_N (PF08496, IPR013703): Peptidase family S49 N-terminal
PHR (PF08005, IPR012983): PHR domain
RCC1 (PF00415, IPR000408): Regulator of chromosome condensation (RCC1) repeat
SH3_3 (PF08239, IPR003646): Bacterial SH3 domain
XPA_N (PF01286, IPR022652): XPA protein N-terminal
zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger
zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain
RCC1_2 (PF13540): Regulator of chromosome condensation (RCC1) repeat
174 MYH9suppressor290.283126.463IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif
Myosin_N (PF02736, IPR004009): Myosin N-terminal SH3-like domain
Myosin_tail_1 (PF01576, IPR002928): Myosin tail
Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain)
175 NADKinteractor70.7620.641NAD_kinase (PF01513, IPR002504): ATP-NAD kinase
176 NBEAL2interactor21.0000Beach (PF02138, IPR000409, SM01026): Beige/BEACH domain
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Laminin_G_3 (PF13385): Concanavalin A-like lectin/glucanases superfamily
PH_BEACH (PF14844, IPR023362): PH domain associated with Beige/BEACH
DUF4704 (PF15787, IPR031570): Domain of unknown function (DUF4704)
DUF4800 (PF16057): Domain of unknown function (DUF4800)
177 NCAPD3interactor70.4293.426DUF3013 (PF11217, IPR021380): Protein of unknown function (DUF3013)
CLASP_N (PF12348, IPR024395): CLASP N terminal
Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1
Cnd3 (PF12719, IPR025977): Nuclear condensing complex subunits, C-term domain
178 NCKAP1interactor70.6672.408Nckap1 (PF09735, IPR019137): Membrane-associated apoptosis protein
179 NCOR1oncoprotein170.27248.398BES1_N (PF05687, IPR008540): BES1/BZR1 plant transcription factor, N-terminal
Lamp (PF01299, IPR002000): Lysosome-associated membrane glycoprotein (Lamp)
MAS20 (PF02064, IPR002056): MAS20 protein import receptor
Neur_chan_memb (PF02932, IPR006029): Neurotransmitter-gated ion-channel transmembrane region
Eapp_C (PF10238, IPR019370): E2F-associated phosphoprotein
Hid1 (PF12722): High-temperature-induced dauer-formation protein
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
DUF3915 (PF13054, IPR025026): Protein of unknown function (DUF3915)
GPS2_interact (PF15784, IPR031557): G-protein pathway suppressor 2-interacting domain
DUF4834 (PF16118, IPR032272): Domain of unknown function (DUF4834)
RBR (PF17208): RNA binding Region
180 NEDD4Lsuppressor230.39067.882WW (PF00397, IPR001202, SM00456): WW domain
HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
181 NEDD8interactor220.50524.156ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
182 NFATC4interactor21.0000RHD_DNA_bind (PF00554, IPR011539): Rel homology DNA-binding domain
RHD_dimer (PF16179, IPR032397): Rel homology dimerisation domain
183 NKD2interactor40.8330.074PDGF_N (PF04692, IPR006782): Platelet-derived growth factor, N terminal region
SelP_N (PF04592, IPR007671): Selenoprotein P, N terminal region
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
184 NOLC1interactor170.40422.986DTHCT (PF08070, IPR012542): DTHCT (NUC029) region
SRP40_C (PF05022, IPR007718): SRP40, C-terminal domain
Stm1_N (PF09598, IPR019084): Stm1
stn_TNFRSF12A (PF12191, IPR022316): Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain
NST1 (PF13945, IPR025279): Salt tolerance down-regulator
SEEEED (PF14797, IPR029394): Serine-rich region of AP3B1, clathrin-adaptor complex
DUF4611 (PF15387, IPR027893): Domain of unknown function (DUF4611)
PAF (PF15715, IPR031444): PCNA-associated factor
IMUP (PF15761, IPR026621): Immortalisation up-regulated protein
NuDC (PF16273, IPR032572): Nuclear distribution C domain
PHC2_SAM_assoc (PF16616): Unstructured region on Polyhomeotic-like protein 1 and 2
185 NOS2interactor160.43818.756FAD_binding_1 (PF00667, IPR003097): FAD binding domain
Flavodoxin_1 (PF00258, IPR008254): Flavodoxin
NAD_binding_1 (PF00175, IPR001433): Oxidoreductase NAD-binding domain
NO_synthase (PF02898, IPR004030): Nitric oxide synthase, oxygenase domain
186 NPM1suppressor630.265526.045Nucleoplasmin (PF03066): Nucleoplasmin
SDA1 (PF05285, IPR007949): SDA1
NPM1-C (PF16276, IPR032569): Nucleophosmin C-terminal domain
187 NSL1interactor100Mis14 (PF08641, IPR013950): Kinetochore protein Mis14 like
188 NTRK1oncoprotein1040.1642243.711I-set (PF07679, IPR013098): Immunoglobulin I-set domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
LRR_8 (PF13855, IPR001611): Leucine rich repeat
TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain
189 NXF1interactor490.141429.935NTF2 (PF02136, IPR002075): Nuclear transport factor 2 (NTF2) domain
Tap-RNA_bind (PF09162, IPR015245): Tap, RNA-binding
TAP_C (PF03943, IPR005637, SM00804): TAP C-terminal domain
LRR_8 (PF13855, IPR001611): Leucine rich repeat
190 OBSL1protein found in more fusions360.341117.023BiPBP_C (PF06832, IPR009647): Penicillin-Binding Protein C-terminus Family
fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
Herpes_gE (PF02480, IPR003404): Alphaherpesvirus glycoprotein E
I-set (PF07679, IPR013098): Immunoglobulin I-set domain
V-set (PF07686, IPR013106): Immunoglobulin V-set domain
Ig_3 (PF13927): Immunoglobulin domain
Ig_4 (PF16680, IPR032052): T-cell surface glycoprotein CD3 delta chain
Izumo-Ig (PF16706, IPR032699): Izumo-like Immunoglobulin domain
191 OLA1interactor190.35739.501Roc (PF08477, IPR013684): Ras of Complex, Roc, domain of DAPkinase
MMR_HSR1 (PF01926, IPR006073): 50S ribosome-binding GTPase
YchF-GTPase_C (PF06071, IPR013029): Protein of unknown function (DUF933)
192 OPTNprotein found in more fusions110.5565.989ARD (PF03079, IPR004313): ARD/ARD' family
bZIP_1 (PF00170, IPR004827): bZIP transcription factor
HALZ (PF02183, IPR003106, SM00340): Homeobox associated leucine zipper
Uso1_p115_C (PF04871, IPR006955): Uso1 / p115 like vesicle tethering protein, C terminal region
NEMO (PF11577, IPR021063): NF-kappa-B essential modulator NEMO
CC2-LZ (PF16516, IPR032419): Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator
193 PABPC4interactor220.48523.582ApbA_C (PF08546, IPR013752): Ketopantoate reductase PanE/ApbA C terminal
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
PABP (PF00658, IPR002004, SM00517): Poly-adenylate binding protein, unique domain
HHV-5_US34A (PF17087, IPR031384): Herpesvirus US34A protein family
194 PAK1oncoprotein150.41820.468PBD (PF00786, IPR000095, SM00285): P21-Rho-binding domain
Pkinase (PF00069, IPR000719): Protein kinase domain
195 PAK2protein found in more fusions220.38154.009PBD (PF00786, IPR000095, SM00285): P21-Rho-binding domain
Pkinase (PF00069, IPR000719): Protein kinase domain
196 PAK4protein found in more fusions140.6159.259PBD (PF00786, IPR000095, SM00285): P21-Rho-binding domain
Pkinase (PF00069, IPR000719): Protein kinase domain
197 PARD3interactor170.43439.659PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
DUF3534 (PF12053, IPR021922): Domain of unknown function (DUF3534)
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
198 PARD6Ainteractor130.41021.921PB1 (PF00564, IPR000270, SM00666): PB1 domain
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
199 PCGF5interactor31.0000DZR (PF12773, IPR025874): Double zinc ribbon
zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger
zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
zf-RING_5 (PF14634, IPR001841): zinc-RING finger domain
zf-C3HC4_4 (PF15227): zinc finger of C3HC4-type, RING
RAWUL (PF16207, IPR032443): RAWUL domain RING finger- and WD40-associated ubiquitin-like
zf-RING_10 (PF16685, IPR032043): zinc RING finger of MSL2
200 PCNTinteractor60.4003.832Caldesmon (PF02029, IPR006018): Caldesmon
CENP-H (PF05837, IPR008426): Centromere protein H (CENP-H)
DUF1640 (PF07798, IPR024461): Protein of unknown function (DUF1640)
DUF755 (PF05501, IPR008474): Domain of unknown function (DUF755)
DUF883 (PF05957, IPR010279): Bacterial protein of unknown function (DUF883)
DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972)
Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family
SlyX (PF04102, IPR007236): SlyX
Syntaxin-6_N (PF09177, IPR015260): Syntaxin 6, N-terminal
Atg14 (PF10186, IPR018791): Vacuolar sorting 38 and autophagy-related subunit 14
Golgin_A5 (PF09787, IPR019177): Golgin subfamily A member 5
Jnk-SapK_ap_N (PF09744, IPR019143): JNK_SAPK-associated protein-1
PACT_coil_coil (PF10495, IPR019528): Pericentrin-AKAP-450 domain of centrosomal targeting protein
zf-C4H2 (PF10146, IPR018482): Zinc finger-containing protein
PP2C_C (PF07830, IPR012911, SM00332): Protein serine/threonine phosphatase 2C, C-terminal domain
Tho2 (PF11262, IPR021418): Transcription factor/nuclear export subunit protein 2
Colicin-DNase (PF12639, IPR024622): DNase/tRNase domain of colicin-like bacteriocin
CENP-Q (PF13094, IPR025212): CENP-Q, a CENPA-CAD centromere complex subunit
DUF4239 (PF14023, IPR025333): Protein of unknown function (DUF4239)
WD40_alt (PF14077, IPR026987): Alternative WD40 repeat motif
FlxA (PF14282, IPR025577): FlxA-like protein
FAM184 (PF15665): Family with sequence similarity 184, A and B
HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1
201 PFASinteractor150.44823.406AIRS_C (PF02769, IPR010918): AIR synthase related protein, C-terminal domain
GATase_5 (PF13507): CobB/CobQ-like glutamine amidotransferase domain
202 PGK1interactor250.44743.392PGK (PF00162, IPR001576): Phosphoglycerate kinase
203 PHBsuppressor270.42249.629Band_7 (PF01145, IPR001107, SM00244): SPFH domain / Band 7 family
DUF4290 (PF14123, IPR025632): Domain of unknown function (DUF4290)
204 PHF3interactor100Mem_trans (PF03547, IPR004776): Membrane transport protein
PHD (PF00628, IPR019787, SM00249): PHD-finger
SPOC (PF07744, IPR012921): SPOC domain
TFIIS_M (PF07500, IPR003618): Transcription factor S-II (TFIIS), central domain
zf-HC5HC2H (PF13771): PHD-like zinc-binding domain
DUF4724 (PF15852, IPR031711): Domain of unknown function (DUF4724)
PNISR (PF15996, IPR031937): Arginine/serine-rich protein PNISR
205 PIAS1suppressor110.40016.320Herpes_capsid (PF06112, IPR009299): Gammaherpesvirus capsid protein
zf-MIZ (PF02891, IPR004181): MIZ/SP-RING zinc finger
PINIT (PF14324, IPR023321): PINIT domain
UPF0544 (PF15749, IPR032739): Uncharacterised protein family UPF0544
206 PNMA1oncoprotein50.6002.317PNMA (PF14893, IPR026523): PNMA
207 PNMA2interactor31.0000PNMA (PF14893, IPR026523): PNMA
208 POTEKPinteractor30.6671.000NA
209 PPFIBP1oncoprotein130.5305.180DUF16 (PF01519, IPR002862): Protein of unknown function DUF16
DUF342 (PF03961, IPR005646): Protein of unknown function (DUF342)
SAM_1 (PF00536, IPR021129, SM00454): SAM domain (Sterile alpha motif)
SAM_2 (PF07647, IPR011510): SAM domain (Sterile alpha motif)
SAM_PNT (PF02198, IPR003118, SM00251): Sterile alpha motif (SAM)/Pointed domain
XkdW (PF09636, IPR019094): XkdW protein
ADIP (PF11559, IPR021622): Afadin- and alpha -actinin-Binding
TMF_DNA_bd (PF12329, IPR022092): TATA element modulatory factor 1 DNA binding
DUF3837 (PF12939, IPR024212): Domain of unknown function (DUF3837)
210 PPP1R14Ainteractor70.3338.986PP1_inhibitor (PF05361, IPR008025): PKC-activated protein phosphatase-1 inhibitor
211 PRCConcoprotein50.6000.626PRCC (PF10253, IPR018800): Mitotic checkpoint regulator, MAD2B-interacting
212 PRDX2interactor160.34226.628AhpC-TSA (PF00578, IPR000866): AhpC/TSA family
1-cysPrx_C (PF10417, IPR019479): C-terminal domain of 1-Cys peroxiredoxin
213 PRKAA1suppressor180.31444.500Pkinase (PF00069, IPR000719): Protein kinase domain
AdenylateSensor (PF16579, IPR032270): Adenylate sensor of SNF1-like protein kinase
214 PRKCAinteractor230.251106.178C2 (PF00168, IPR000008, SM00239): C2 domain
Pkinase (PF00069, IPR000719): Protein kinase domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain)
215 PRKCDsuppressor130.42410.912Pkinase (PF00069, IPR000719): Protein kinase domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain)
216 PRKCEsuppressor100.36112.287C2 (PF00168, IPR000008, SM00239): C2 domain
Pkinase (PF00069, IPR000719): Protein kinase domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain)
217 PRKCIinteractor160.39235.535PB1 (PF00564, IPR000270, SM00666): PB1 domain
Pkinase (PF00069, IPR000719): Protein kinase domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain)
218 PRKCZinteractor210.36855.699PB1 (PF00564, IPR000270, SM00666): PB1 domain
Pkinase (PF00069, IPR000719): Protein kinase domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain)
219 PRKD1oncoprotein110.42211.259PH (PF00169, IPR001849, SM00233): PH domain
Pkinase (PF00069, IPR000719): Protein kinase domain
C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain)
220 PRMT5protein found in more fusions210.24751.652PRMT5 (PF05185, IPR025799): PRMT5 arginine-N-methyltransferase
221 PRPF18interactor100Prp18 (PF02840, IPR004098): Prp18 domain
PRP4 (PF08799, IPR014906): pre-mRNA processing factor 4 (PRP4) like
222 PRR14Linteractor100Tantalus (PF15386, IPR028149): Drosophila Tantalus-like
223 PSMA5oncoprotein180.34020.277Proteasome (PF00227, IPR001353): Proteasome subunit
Proteasome_A_N (PF10584, IPR000426, SM00948): Proteasome subunit A N-terminal signature
224 PTPN14oncoprotein110.34512.388FERM_C (PF09380, IPR018980): FERM C-terminal PH-like domain
FERM_M (PF00373, IPR019748): FERM central domain
FERM_N (PF09379, IPR018979): FERM N-terminal domain
Y_phosphatase (PF00102, IPR000242, SM00194): Protein-tyrosine phosphatase
225 PTPRAinteractor40.5000.855DUF1180 (PF06679, IPR009565): Protein of unknown function (DUF1180)
Y_phosphatase2 (PF03162, IPR004861): Tyrosine phosphatase family
Y_phosphatase (PF00102, IPR000242, SM00194): Protein-tyrosine phosphatase
EphA2_TM (PF14575, IPR027936): Ephrin type-A receptor 2 transmembrane domain
226 PTPROinteractor40.5001.439CDC24 (PF06395, IPR010481): CDC24 Calponin
fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
Y_phosphatase (PF00102, IPR000242, SM00194): Protein-tyrosine phosphatase
227 RAB11FIP2protein found in more fusions70.9330.250C2 (PF00168, IPR000008, SM00239): C2 domain
RBD-FIP (PF09457, IPR019018): FIP domain
228 RAD52oncoprotein60.5000.805Rad52_Rad22 (PF04098, IPR007232): Rad52/22 family double-strand break repair protein
DUF2335 (PF10097, IPR019284): Predicted membrane protein (DUF2335)
229 RAF1oncoprotein320.325134.454Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
RBD (PF02196, IPR003116, SM00455): Raf-like Ras-binding domain
C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain)
230 RAI14interactor90.5836.202Ank (PF00023, IPR002110, SM00248): Ankyrin repeat
Fez1 (PF06818): Fez1
FliJ (PF02050, IPR012823): Flagellar FliJ protein
Uso1_p115_C (PF04871, IPR006955): Uso1 / p115 like vesicle tethering protein, C terminal region
DUF2408 (PF10303, IPR018810): Protein of unknown function (DUF2408)
TMF_DNA_bd (PF12329, IPR022092): TATA element modulatory factor 1 DNA binding
MscS_porin (PF12795, IPR024393): Mechanosensitive ion channel porin domain
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
AAA_13 (PF13166, IPR026866): AAA domain
Ank_5 (PF13857): Ankyrin repeats (many copies)
PKcGMP_CC (PF16808, IPR031831): Coiled-coil N-terminus of cGMP-dependent protein kinase
231 RALGPS2oncoprotein40.8330.041PH (PF00169, IPR001849, SM00233): PH domain
RasGEF (PF00617, IPR001895, SM00147): RasGEF domain
232 RAP1GAP2interactor31.0000Rap_GAP (PF02145, IPR000331): Rap/ran-GAP
233 RASAL3interactor21.0000ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16)
Baculo_PEP_C (PF04513, IPR007601): Baculovirus polyhedron envelope protein, PEP, C terminus
C2 (PF00168, IPR000008, SM00239): C2 domain
PH (PF00169, IPR001849, SM00233): PH domain
RasGAP (PF00616, IPR001936, SM00323): GTPase-activator protein for Ras-like GTPase
Tropomyosin_1 (PF12718, IPR000533): Tropomyosin like
DUF4140 (PF13600, IPR025554): N-terminal domain of unknown function (DUF4140)
234 RASSF2suppressor70.7620.878RA (PF00788, IPR000159, SM00314): Ras association (RalGDS/AF-6) domain
Nore1-SARAH (PF16517, IPR011524): Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain
235 RBM26interactor50.9000.154Afi1 (PF07792, IPR012860): Docking domain of Afi1 for Arf3 in vesicle trafficking
PWI (PF01480, IPR002483, SM00311): PWI domain
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
TT_ORF1 (PF02956, IPR004219): TT viral orf 1
zf-CCCH (PF00642, IPR000571): Zinc finger C-x8-C-x5-C-x3-H type (and similar)
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
Nup35_RRM_2 (PF14605): Nup53/35/40-type RNA recognition motif
236 RBM27interactor100DUF342 (PF03961, IPR005646): Protein of unknown function (DUF342)
Exonuc_VII_L (PF02601, IPR020579): Exonuclease VII, large subunit
PWI (PF01480, IPR002483, SM00311): PWI domain
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
zf-CCCH (PF00642, IPR000571): Zinc finger C-x8-C-x5-C-x3-H type (and similar)
DUF2203 (PF09969, IPR018699): Uncharacterized conserved protein (DUF2203)
DUF2408 (PF10303, IPR018810): Protein of unknown function (DUF2408)
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
Nup35_RRM_2 (PF14605): Nup53/35/40-type RNA recognition motif
237 REM1interactor41.0000Ras (PF00071, IPR001806, SM00173): Ras family
AAA_33 (PF13671): AAA domain
238 RFWD2suppressor130.43914.298Herpes_capsid (PF06112, IPR009299): Gammaherpesvirus capsid protein
IncA (PF04156, IPR007285): IncA protein
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
WD40_like (PF17005, IPR031544): WD40-like domain
239 RGS3oncoprotein40.8330.133C2 (PF00168, IPR000008, SM00239): C2 domain
CDC45 (PF02724, IPR003874): CDC45-like protein
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
RGS (PF00615, IPR000342, SM00315): Regulator of G protein signaling domain
Astro_capsid_p (PF12226, IPR022027): Turkey astrovirus capsid protein
240 RMDN3interactor50.7000.956TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat
TPR_11 (PF13414, IPR011990): TPR repeat
TPR_16 (PF13432): Tetratricopeptide repeat
241 RPL31interactor160.43313.827Ribosomal_L31e (PF01198, IPR000054): Ribosomal protein L31e
242 RPRD1Ainteractor80.4643.431CTD_bind (PF04818, IPR006903): RNA polymerase II-binding domain.
GlutR_N (PF05201, IPR015895): Glutamyl-tRNAGlu reductase, N-terminal domain
CTK3 (PF12243, IPR024638): CTD kinase subunit gamma CTK3
CREPT (PF16566, IPR032337): Cell-cycle alteration and expression-elevated protein in tumour
243 RPS6KA5interactor80.3217.954Choline_kinase (PF01633): Choline/ethanolamine kinase
Pkinase (PF00069, IPR000719): Protein kinase domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein
244 RRADinteractor21.0000Ras (PF00071, IPR001806, SM00173): Ras family
AAA_16 (PF13191): AAA ATPase domain
245 SAMD4Binteractor60.6670.791PHAT (PF09246, IPR015327): PHAT
SAM_1 (PF00536, IPR021129, SM00454): SAM domain (Sterile alpha motif)
246 SAMSN1interactor70.8570.130SAM_2 (PF07647, IPR011510): SAM domain (Sterile alpha motif)
SH3_2 (PF07653, IPR011511): Variant SH3 domain
SLY (PF12485, IPR021090): Lymphocyte signaling adaptor protein
247 SAV1oncoprotein110.36413.640WW (PF00397, IPR001202, SM00456): WW domain
248 SDF4interactor90.30615.219Pex14_N (PF04695, IPR006785): Peroxisomal membrane anchor protein (Pex14p) conserved region
EF-hand_1 (PF00036, IPR002048, SM00054): EF hand
EF-hand_5 (PF13202, IPR002048): EF hand
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
249 SEC61A1interactor80.5712.449DUF1430 (PF07242, IPR006541): Protein of unknown function (DUF1430)
SecY (PF00344, IPR002208): SecY translocase
Plug_translocon (PF10559, IPR019561): Plug domain of Sec61p
250 SF3B1oncoprotein220.39040.580Dopey_N (PF04118, IPR007249): Dopey, N-terminal
HEAT (PF02985, IPR000357): HEAT repeat
SF3b1 (PF08920, IPR015016): Splicing factor 3B subunit 1
UNC45-central (PF11701, IPR024660): Myosin-binding striated muscle assembly central
Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region
HEAT_EZ (PF13513): HEAT-like repeat
HEAT_2 (PF13646): HEAT repeats
251 SFNsuppressor680.121935.66114-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
252 SGK1oncoprotein140.42319.299Pkinase (PF00069, IPR000719): Protein kinase domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
PX (PF00787, IPR001683, SM00312): PX domain
253 SH3GL1oncoprotein60.5003.333BAR (PF03114, IPR004148, SM00721): BAR domain
PhnG (PF06754, IPR009609): Phosphonate metabolism protein PhnG
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
254 SHMT2interactor230.28566.708SHMT (PF00464, IPR001085): Serine hydroxymethyltransferase
255 SIK1suppressor50.8000.600Pkinase (PF00069, IPR000719): Protein kinase domain
256 SIK2interactor120.5008.402Pkinase (PF00069, IPR000719): Protein kinase domain
257 SIK3oncoprotein90.6392.854GET2 (PF08690, IPR028143): GET complex subunit GET2
Pkinase (PF00069, IPR000719): Protein kinase domain
Jnk-SapK_ap_N (PF09744, IPR019143): JNK_SAPK-associated protein-1
258 SIMC1interactor30.6670.400FANCI_S3 (PF14677, IPR029313): FANCI solenoid 3
259 SLC9A3R1suppressor150.41817.293EBP50_C (PF09007, IPR015098): EBP50, C-terminal
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
260 SLKinteractor40.8330.041Pepsin-I3 (PF06394, IPR010480): Pepsin inhibitor-3-like repeated domain
Pkinase (PF00069, IPR000719): Protein kinase domain
TMPIT (PF07851, IPR012926): TMPIT-like protein
TrbI_Ftype (PF09677, IPR014115): Type-F conjugative transfer system protein (TrbI_Ftype)
PKK (PF12474, IPR022165): Polo kinase kinase
261 SMC1Aoncoprotein190.32736.654SMC_N (PF02463, IPR003395): RecF/RecN/SMC N terminal domain
262 SNRNP40interactor110.4736.646WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
263 SNRPD2P1interactor21.0000NA
264 SNRPEinteractor180.45121.211LSM (PF01423, IPR001163): LSM domain
265 SNRPFinteractor170.41222.267LSM (PF01423, IPR001163): LSM domain
266 SNX24interactor21.0000PX (PF00787, IPR001683, SM00312): PX domain
267 SORBS2oncoprotein130.4859.290Sorb (PF02208, IPR003127, SM00459): Sorbin homologous domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
SH3_9 (PF14604, IPR001452): Variant SH3 domain
268 SOX2oncoprotein190.20356.547HMG_box (PF00505, IPR009071, SM00398): HMG (high mobility group) box
SOXp (PF12336, IPR022097): SOX transcription factor
269 SPIRE2interactor21.0000FYVE (PF01363, IPR000306, SM00064): FYVE zinc finger
PrmA (PF06325, IPR010456): Ribosomal protein L11 methyltransferase (PrmA)
FYVE_2 (PF02318, IPR010911): FYVE-type zinc finger
KIND (PF16474, IPR011019, SM00750): Kinase non-catalytic C-lobe domain
270 SPRYD3interactor21.0000Radial_spoke (PF04712, IPR006802): Radial spokehead-like protein
SPRY (PF00622, IPR003877, SM00449): SPRY domain
271 SQSTM1oncoprotein330.244180.266PB1 (PF00564, IPR000270, SM00666): PB1 domain
ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type
UBA_5 (PF16577, IPR015940): UBA domain
272 SRSF8interactor40.5000.277RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
SPX (PF03105, IPR004331): SPX domain
273 SSFA2interactor90.4448.031KRAP_IP3R_bind (PF14722, IPR029325): Ki-ras-induced actin-interacting protein-IP3R-interacting domain
SSFA2_C (PF14723, IPR029326): Sperm-specific antigen 2 C-terminus
274 SSX2IPinteractor120.30913.936ZapB (PF06005, IPR009252): Cell division protein ZapB
ERM (PF00769, IPR011259): Ezrin/radixin/moesin family
Surfac_D-trimer (PF09006, IPR015097): Lung surfactant protein D coiled-coil trimerisation
ADIP (PF11559, IPR021622): Afadin- and alpha -actinin-Binding
YqzH (PF14164, IPR025546): YqzH-like protein
275 STACinteractor30.6670.333SH3_2 (PF07653, IPR011511): Variant SH3 domain
C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain)
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
STAC2_u1 (PF16664): Unstructured on SH3 and cysteine-rich domain-containing protein 2
276 STAU1protein found in more fusions320.33396.674dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif
Staufen_C (PF16482, IPR032478): Staufen C-terminal domain
277 STK38interactor100.3897.793MEKHLA (PF08670, IPR013978): MEKHLA domain
Pkinase (PF00069, IPR000719): Protein kinase domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
278 SYN2interactor31.0000LpxD (PF04613, IPR020573): UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD
SPX (PF03105, IPR004331): SPX domain
Synapsin_C (PF02750, IPR020898): Synapsin, ATP binding domain
Synapsin_N (PF10581, IPR019736): Synapsin N-terminal
DUF2076 (PF09849, IPR018648): Uncharacterized protein conserved in bacteria (DUF2076)
Synapsin (PF02078, IPR020897): Synapsin, N-terminal domain
279 SYNPOinteractor110.45511.333Calsarcin (PF05556, IPR008438): Calcineurin-binding protein (Calsarcin)
280 SYNPO2suppressor50.8000.239Calsarcin (PF05556, IPR008438): Calcineurin-binding protein (Calsarcin)
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
281 TAB2oncoprotein140.47416.860CUE (PF02845, IPR003892, SM00546): CUE domain
DivIC (PF04977, IPR007060): Septum formation initiator
Mnd1 (PF03962, IPR005647): Mnd1 family
zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others
282 TBC1D4interactor100.5782.713DUF632 (PF04782, IPR006867): Protein of unknown function (DUF632)
PID (PF00640, IPR006020, SM00462): Phosphotyrosine interaction domain (PTB/PID)
RecR (PF02132, IPR023628): RecR protein
RabGAP-TBC (PF00566, IPR000195, SM00164): Rab-GTPase-TBC domain
DUF3350 (PF11830, IPR021785): Domain of unknown function (DUF3350)
UPF0449 (PF15136, IPR028227): Uncharacterised protein family UPF0449
DUF4806 (PF16064, IPR032071): Domain of unknown function (DUF4806)
283 TBXA2Rinteractor50.5000.9057tm_1 (PF00001, IPR000276): 7 transmembrane receptor (rhodopsin family)
284 TCEB3suppressor80.3936.016Elongin_A (PF06881, IPR010684): RNA polymerase II transcription factor SIII (Elongin) subunit A
Med26 (PF08711, IPR017923): TFIIS helical bundle-like domain
285 TERToncoprotein80.6072.404RVT_1 (PF00078, IPR000477): Reverse transcriptase (RNA-dependent DNA polymerase)
Telomerase_RBD (PF12009, IPR021891, SM00975): Telomerase ribonucleoprotein complex - RNA binding domain
286 TESPA1interactor31.0000PUB (PF09409, IPR018997): PUB domain
DUF2939 (PF11159, IPR021330): Protein of unknown function (DUF2939)
KRAP_IP3R_bind (PF14722, IPR029325): Ki-ras-induced actin-interacting protein-IP3R-interacting domain
287 TGM2protein found in more fusions220.32960.969Transglut_C (PF00927, IPR008958): Transglutaminase family, C-terminal ig like domain
Transglut_N (PF00868, IPR001102): Transglutaminase family
Transglut_core (PF01841, IPR002931, SM00460): Transglutaminase-like superfamily
288 TIMM13interactor80.39310.465zf-Tim10_DDP (PF02953, IPR004217): Tim10/DDP family zinc finger
289 TJP2oncoprotein100.5564.106PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
SH3_2 (PF07653, IPR011511): Variant SH3 domain
Guanylate_kin (PF00625, IPR008145, SM00072): Guanylate kinase
290 TNFAIP3suppressor130.45510.531OTU (PF02338, IPR003323): OTU-like cysteine protease
zf-A20 (PF01754, IPR002653, SM00259): A20-like zinc finger
Thioredoxin_3 (PF13192, IPR012336): Thioredoxin domain
291 TNK1suppressor90.7500.636Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
SH3_9 (PF14604, IPR001452): Variant SH3 domain
HOIP-UBA (PF16678, IPR032065): UB-associated-like domain of HOIP or E3 ubiquitin-protein ligase
292 TNS1interactor21.0000Protocadherin (PF08374, IPR013585): Protocadherin
PTB (PF08416, IPR013625): Phosphotyrosine-binding domain
SH2 (PF00017, IPR000980, SM00252): SH2 domain
PTEN_C2 (PF10409, IPR014020): C2 domain of PTEN tumour-suppressor protein
293 TP53suppressor710.160987.201DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region
P53 (PF00870, IPR011615): P53 DNA-binding domain
P53_tetramer (PF07710, IPR010991): P53 tetramerisation motif
294 TP53BP1suppressor180.40530.83053-BP1_Tudor (PF09038, IPR015125): Tumour suppressor p53-binding protein-1 Tudor
BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain
FXMRP1_C_core (PF12235, IPR022034): Fragile X-related 1 protein core C terminal
DUF4772 (PF15997, IPR031940): Domain of unknown function (DUF4772)
BRCT_2 (PF16589, IPR001357): BRCT domain, a BRCA1 C-terminus domain
295 TP53BP2suppressor150.46720.258ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16)
Erp_C (PF06780, IPR009618): Erp protein C-terminus
SlyX (PF04102, IPR007236): SlyX
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
Ank_5 (PF13857): Ankyrin repeats (many copies)
296 TPH1interactor21.0000ACT (PF01842, IPR002912): ACT domain
Biopterin_H (PF00351, IPR019774): Biopterin-dependent aromatic amino acid hydroxylase
297 TRA2Binteractor170.55116.673RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
Transformer (PF06495, IPR010519): Fruit fly transformer protein
298 TRIM21interactor170.42521.617DUF313 (PF03754, IPR005508): Domain of unknown function (DUF313)
SPRY (PF00622, IPR003877, SM00449): SPRY domain
zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger
PRY (PF13765, IPR006574, SM00589): SPRY-associated domain
Prok-RING_1 (PF14446): Prokaryotic RING finger family 1
zf-C3HC4_4 (PF15227): zinc finger of C3HC4-type, RING
299 TRIM32suppressor150.5829.301NHL (PF01436, IPR001258): NHL repeat
zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger
Zn_Tnp_IS1595 (PF12760, IPR024442): Transposase zinc-ribbon domain
zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger
HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1
300 TSC1suppressor110.5336.187Bcr-Abl_Oligo (PF09036, IPR015123): Bcr-Abl oncoprotein oligomerisation domain
DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664)
Hamartin (PF04388, IPR007483): Hamartin protein
301 TSC2suppressor120.5769.642Rap_GAP (PF02145, IPR000331): Rap/ran-GAP
Tuberin (PF03542, IPR018515): Tuberin
DUF3384 (PF11864, IPR024584): Domain of unknown function (DUF3384)
Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1
302 TUBA3Cinteractor80.8930.243Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain
Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain
303 TUBBinteractor420.307177.176Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain
Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain
304 TUBG1protein found in more fusions220.29065.163Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain
Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain
305 U2AF2protein found in more fusions320.42866.385RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
Transformer (PF06495, IPR010519): Fruit fly transformer protein
306 UBCprotein found in more fusions630.221615.002ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
307 UBE2V1interactor100.6444.183UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
308 UBE3Aoncoprotein160.36232.710HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
PCM1_C (PF15717, IPR031446): Pericentriolar material 1 C terminus
AZUL (PF16558, IPR032353): Amino-terminal Zinc-binding domain of ubiquitin ligase E3A
309 UCHL5oncoprotein160.35235.229Peptidase_C12 (PF01088, IPR001578): Ubiquitin carboxyl-terminal hydrolase, family 1
310 UCP2interactor31.0000Mito_carr (PF00153, IPR018108): Mitochondrial carrier protein
311 UCP3interactor31.0000Mito_carr (PF00153, IPR018108): Mitochondrial carrier protein
312 UHRF1BP1Loncoprotein30.6670.100Ribosomal_L29 (PF00831, IPR001854): Ribosomal L29 protein
DUF3381 (PF11861, IPR024576): Domain of unknown function (DUF3381)
Chorein_N (PF12624, IPR026854): N-terminal region of Chorein or VPS13
VPS13 (PF16908, IPR031646): Vacuolar sorting-associated protein 13, N-terminal
313 UNKinteractor210.29056.846MbeD_MobD (PF04899, IPR006983): MbeD/MobD like
NUDE_C (PF04880, IPR006964): NUDE protein, C-terminal conserved region
zf-CCCH (PF00642, IPR000571): Zinc finger C-x8-C-x5-C-x3-H type (and similar)
DUF3450 (PF11932, IPR016866): Protein of unknown function (DUF3450)
zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
zf-CCCH_2 (PF14608): RNA-binding, Nab2-type zinc finger
Torus (PF16131, IPR032297): Torus domain
314 USP8interactor130.7272.663DUF1510 (PF07423, IPR009988): Protein of unknown function (DUF1510)
USP8_dimer (PF08969, IPR015063): USP8 dimerisation domain
SET (PF00856, IPR001214, SM00317): SET domain
UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase
Rhodanese (PF00581, IPR001763, SM00450): Rhodanese-like domain
NAM-associated (PF14303, IPR029466): No apical meristem-associated C-terminal domain
315 VCAM1interactor320.33966.534C2-set (PF05790, IPR008424): Immunoglobulin C2-set domain
I-set (PF07679, IPR013098): Immunoglobulin I-set domain
ig (PF00047, IPR013151, SM00409): Immunoglobulin domain
V-set (PF07686, IPR013106): Immunoglobulin V-set domain
Ig_3 (PF13927): Immunoglobulin domain
316 VCLoncoprotein290.36591.041Vinculin (PF01044, IPR006077): Vinculin family
317 VCPprotein found in more fusions630.272513.943AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA)
CDC48_2 (PF02933, IPR004201, SM01072): Cell division protein 48 (CDC48), domain 2
CDC48_N (PF02359, IPR003338, SM01073): Cell division protein 48 (CDC48), N-terminal domain
TniB (PF05621, IPR008868): Bacterial TniB protein
Vps4_C (PF09336, IPR015415): Vps4 C terminal oligomerisation domain
DUF3944 (PF13099, IPR025217): Domain of unknown function (DUF3944)
318 VIMsuppressor310.34986.944Filament (PF00038, IPR001664): Intermediate filament protein
Filament_head (PF04732, IPR006821): Intermediate filament head (DNA binding) region
319 WDR62interactor100.5566.362eIF2A (PF08662, IPR013979): Eukaryotic translation initiation factor eIF2A
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
320 WNK1interactor150.52718.041SynMuv_product (PF06047, IPR009269): Ras-induced vulval development antagonist
Pkinase (PF00069, IPR000719): Protein kinase domain
TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
OSR1_C (PF12202, IPR024678): Oxidative-stress-responsive kinase 1 C terminal
321 WNK2suppressor31.0000DUF1180 (PF06679, IPR009565): Protein of unknown function (DUF1180)
Herpes_capsid (PF06112, IPR009299): Gammaherpesvirus capsid protein
Pkinase (PF00069, IPR000719): Protein kinase domain
PRCC (PF10253, IPR018800): Mitotic checkpoint regulator, MAD2B-interacting
OSR1_C (PF12202, IPR024678): Oxidative-stress-responsive kinase 1 C terminal
322 WWOXsuppressor220.169102.123adh_short (PF00106, IPR002198): short chain dehydrogenase
WW (PF00397, IPR001202, SM00456): WW domain
323 WWTR1interactor70.7620.973WW (PF00397, IPR001202, SM00456): WW domain
324 XPO1interactor800.1281538.512CRM1_C (PF08767, IPR014877, SM01102): CRM1 C terminal
Hydrolase_3 (PF08282, IPR023214): haloacid dehalogenase-like hydrolase
IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain
Xpo1 (PF08389, IPR013598): Exportin 1-like protein
Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region
325 XRCC6oncoprotein360.284151.753Ku (PF02735, IPR006164, SM00559): Ku70/Ku80 beta-barrel domain
Ku_C (PF03730, IPR005160): Ku70/Ku80 C-terminal arm
Ku_N (PF03731, IPR005161): Ku70/Ku80 N-terminal alpha/beta domain
SAP (PF02037, IPR003034, SM00513): SAP domain
326 YAP1suppressor250.30780.169Bindin (PF02084, IPR000775): Bindin
WW (PF00397, IPR001202, SM00456): WW domain
GspL_C (PF12693, IPR025691): GspL periplasmic domain
FAM181 (PF15238, IPR029359): FAM181
327 YWHABinteractor1320.0964025.56214-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
Virulence_fact (PF13769, IPR025989): Virulence factor
328 YWHAEoncoprotein1490.1005470.83014-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
329 YWHAGprotein found in more fusions1330.1053976.24014-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
330 YWHAHprotein found in more fusions880.1441409.97914-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
331 YWHAQinteractor1370.1074172.94014-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
332 ZAKprotein found in more fusions80.4294.899Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
SAM_1 (PF00536, IPR021129, SM00454): SAM domain (Sterile alpha motif)
SAM_2 (PF07647, IPR011510): SAM domain (Sterile alpha motif)
DUF3552 (PF12072, IPR022711): Domain of unknown function (DUF3552)
333 ZFYVE19interactor70.5712.958Cwf_Cwc_15 (PF04889, IPR006973): Cwf15/Cwc15 cell cycle control protein
DUF1690 (PF07956, IPR012471): Protein of Unknown function (DUF1690)
FYVE (PF01363, IPR000306, SM00064): FYVE zinc finger
Rpr2 (PF04032, IPR007175): RNAse P Rpr2/Rpp21/SNM1 subunit domain
zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger
334 ZHX2suppressor30.6670.069zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
Homez (PF11569, IPR024578): Homeodomain leucine-zipper encoding, Homez
zf-H2C2_5 (PF13909): C2H2-type zinc-finger domain
DUF4343 (PF14243, IPR025643): Domain of unknown function (DUF4343)
335 ZNF839interactor30.6670.061DUF4764 (PF15961, IPR031885): Domain of unknown function (DUF4764)

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