1 |
WAC | parental protein | 33 | 0.056 | 889.667 | DUF1319 (PF07028, IPR010746): Protein of unknown function (DUF1319) MGC-24 (PF05283, IPR007947): Multi-glycosylated core protein 24 (MGC-24), sialomucin WW (PF00397, IPR001202, SM00456): WW domain MDFI (PF15316, IPR026134): MyoD family inhibitor CCDC106 (PF15794, IPR031591): Coiled-coil domain-containing protein 106 |
2 |
AKAP9 | oncoprotein | 2 | 1.000 | 0 | ACCA (PF03255, IPR001095): Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16) DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664) DUF724 (PF05266, IPR007930): Protein of unknown function (DUF724) ZYG-11_interact (PF05884, IPR008574): Interactor of ZYG-11 FlaC_arch (PF05377, IPR008039): Flagella accessory protein C (FlaC) Hema_stalk (PF08720, IPR014831): Influenza C hemagglutinin stalk IncA (PF04156, IPR007285): IncA protein Laminin_II (PF06009, IPR010307): Laminin Domain II Pox_A_type_inc (PF04508, IPR007596): Viral A-type inclusion protein repeat Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein Seryl_tRNA_N (PF02403, IPR015866): Seryl-tRNA synthetase N-terminal domain Spc24 (PF08286, IPR013252): Spc24 subunit of Ndc80 TBPIP (PF07106, IPR010776): Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Uso1_p115_C (PF04871, IPR006955): Uso1 / p115 like vesicle tethering protein, C terminal region ApoO (PF09769, IPR019166): Apolipoprotein O Golgin_A5 (PF09787, IPR019177): Golgin subfamily A member 5 Jnk-SapK_ap_N (PF09744, IPR019143): JNK_SAPK-associated protein-1 Macoilin (PF09726, IPR019130): Transmembrane protein PACT_coil_coil (PF10495, IPR019528): Pericentrin-AKAP-450 domain of centrosomal targeting protein bZIP_2 (PF07716, IPR004827, SM00338): Basic region leucine zipper DUF4200 (PF13863, IPR025252): Domain of unknown function (DUF4200) FlxA (PF14282, IPR025577): FlxA-like protein DUF4404 (PF14357, IPR025516): Domain of unknown function (DUF4404) DUF4407 (PF14362, IPR025519): Domain of unknown function (DUF4407) UPF0449 (PF15136, IPR028227): Uncharacterised protein family UPF0449 PRKG1_interact (PF15898, IPR031775): cGMP-dependent protein kinase interacting domain FAM76 (PF16046, IPR032017): FAM76 protein ABC_tran_CTD (PF16326, IPR032524): ABC transporter C-terminal domain HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1 PKcGMP_CC (PF16808, IPR031831): Coiled-coil N-terminus of cGMP-dependent protein kinase |
3 |
APP | protein found in more fusions | 5 | 0.500 | 3.000 | APP_N (PF02177, IPR015849, SM00006): Amyloid A4 N-terminal heparin-binding Beta-APP (PF03494, IPR013803): Beta-amyloid peptide (beta-APP) BUD22 (PF09073, IPR015158): BUD22 IncA (PF04156, IPR007285): IncA protein Kunitz_BPTI (PF00014, IPR002223, SM00131): Kunitz/Bovine pancreatic trypsin inhibitor domain APP_amyloid (PF10515, IPR019543): beta-amyloid precursor protein C-terminus APP_Cu_bd (PF12924, IPR011178): Copper-binding of amyloid precursor, CuBD APP_E2 (PF12925, IPR024329): E2 domain of amyloid precursor protein |
4 |
CBR1 | interactor | 1 | 0 | 0 | adh_short (PF00106, IPR002198): short chain dehydrogenase |
5 |
CDKN2AIPNL | interactor | 1 | 0 | 0 | XTBD (PF11952, IPR021859): XRN-Two Binding Domain, XTBD |
6 |
CEP170P1 | interactor | 3 | 1.000 | 0 | NA |
7 |
CRKL | interactor | 1 | 0 | 0 | SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_2 (PF07653, IPR011511): Variant SH3 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain |
8 |
DYDC1 | interactor | 1 | 0 | 0 | Dpy-30 (PF05186, IPR007858): Dpy-30 motif LRS4 (PF10422, IPR018479): Monopolin complex subunit LRS4 |
9 |
EWSR1 | oncoprotein | 5 | 0.500 | 3.000 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SVS_QK (PF10578, IPR018942): Seminal vesicle protein repeat zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 Keratin_2_head (PF16208, IPR032444): Keratin type II head |
10 |
KLC3 | interactor | 4 | 0.667 | 1.000 | TPR_4 (PF07721, IPR011717): Tetratricopeptide repeat TMF_TATA_bd (PF12325, IPR022091): TATA element modulatory factor 1 TATA binding TPR_12 (PF13424): Tetratricopeptide repeat |
11 |
KRT15 | interactor | 3 | 0.667 | 1.000 | Filament (PF00038, IPR001664): Intermediate filament protein Keratin_2_head (PF16208, IPR032444): Keratin type II head |
12 |
LNX1 | interactor | 6 | 0.400 | 6.000 | PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) zf-rbx1 (PF12678, IPR024766): RING-H2 zinc finger domain zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger) |
13 |
MTUS2 | suppressor | 3 | 1.000 | 0 | DUF496 (PF04363, IPR007458): Protein of unknown function (DUF496) RNA_pol_Rpb1_R (PF05001, IPR000684): RNA polymerase Rpb1 C-terminal repeat FAM184 (PF15665): Family with sequence similarity 184, A and B |
14 |
NDE1 | protein found in more fusions | 2 | 0 | 0 | NUDE_C (PF04880, IPR006964): NUDE protein, C-terminal conserved region TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein PRKG1_interact (PF15898, IPR031775): cGMP-dependent protein kinase interacting domain |
15 |
NFE2L2 | interactor | 1 | 0 | 0 | bZIP_Maf (PF03131, IPR004826): bZIP Maf transcription factor |
16 |
POLR2A | protein found in more fusions | 4 | 0.667 | 1.000 | RNA_pol_Rpb1_1 (PF04997, IPR007080): RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 (PF00623, IPR000722): RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 (PF04983, IPR007066): RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 (PF05000, IPR007083): RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_5 (PF04998, IPR007081): RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_R (PF05001, IPR000684): RNA polymerase Rpb1 C-terminal repeat |
17 |
QTRT2 | interactor | 1 | 0 | 0 | TGT (PF01702, IPR002616): Queuine tRNA-ribosyltransferase |
18 |
RNF20 | interactor | 8 | 0.476 | 10.333 | Allexi_40kDa (PF05549, IPR008398): Allexivirus 40kDa protein Atrophin-1 (PF03154, IPR002951): Atrophin-1 family BRE1 (PF08647, IPR013956): BRE1 E3 ubiquitin ligase DUF1690 (PF07956, IPR012471): Protein of Unknown function (DUF1690) HrpB7 (PF09486, IPR013392): Bacterial type III secretion protein (HrpB7) Trypan_PARP (PF05887, IPR008882): Procyclic acidic repetitive protein (PARP) Uso1_p115_C (PF04871, IPR006955): Uso1 / p115 like vesicle tethering protein, C terminal region Sox_N (PF12444, IPR022151): Sox developmental protein N terminal DUF4200 (PF13863, IPR025252): Domain of unknown function (DUF4200) zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger) DUF4407 (PF14362, IPR025519): Domain of unknown function (DUF4407) Rootletin (PF15035): Ciliary rootlet component, centrosome cohesion |
19 |
RNF40 | protein found in more fusions | 8 | 0.476 | 10.333 | BRE1 (PF08647, IPR013956): BRE1 E3 ubiquitin ligase DUF745 (PF05335, IPR007999): Protein of unknown function (DUF745) ZapB (PF06005, IPR009252): Cell division protein ZapB EzrA (PF06160, IPR010379): Septation ring formation regulator, EzrA FlgN (PF05130, IPR007809): FlgN protein Pox_A_type_inc (PF04508, IPR007596): Viral A-type inclusion protein repeat SpoIIE (PF07228, IPR001932): Stage II sporulation protein E (SpoIIE) T5orf172 (PF10544, IPR018306, SM00974): T5orf172 domain XhlA (PF10779, IPR019715): Haemolysin XhlA ADIP (PF11559, IPR021622): Afadin- and alpha -actinin-Binding zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger) KASH_CCD (PF14662, IPR028168): Coiled-coil region of CCDC155 or KASH Snapin_Pallidin (PF14712, IPR028119): Snapin/Pallidin zf-RING_6 (PF14835): zf-RING of BARD1-type protein |
20 |
SIRT6 | suppressor | 3 | 1.000 | 0 | SIR2 (PF02146, IPR003000): Sir2 family TPP_enzyme_M (PF00205, IPR012000): Thiamine pyrophosphate enzyme, central domain |
21 |
SLAIN2 | interactor | 3 | 0.667 | 1.000 | bZIP_1 (PF00170, IPR004827): bZIP transcription factor SLAIN (PF15301, IPR026179): SLAIN motif-containing family |
22 |
SYTL5 | interactor | 1 | 0 | 0 | C2 (PF00168, IPR000008, SM00239): C2 domain FYVE_2 (PF02318, IPR010911): FYVE-type zinc finger |
23 |
TLN1 | interactor | 1 | 0 | 0 | DUF1013 (PF06242, IPR010421): Protein of unknown function (DUF1013) DUF948 (PF06103, IPR009293): Bacterial protein of unknown function (DUF948) FERM_M (PF00373, IPR019748): FERM central domain FERM_N (PF09379, IPR018979): FERM N-terminal domain IRS (PF02174, IPR002404, SM00310): PTB domain (IRS-1 type) Talin_middle (PF09141, IPR015224): Talin, middle domain VBS (PF08913, IPR015009): Vinculin Binding Site CoatB (PF10389, IPR008020): Bacteriophage coat protein B LOH1CR12 (PF10158, IPR018780): Tumour suppressor protein I_LWEQ (PF01608, IPR002558, SM00307): I/LWEQ domain TAN (PF11640, IPR021668): Telomere-length maintenance and DNA damage repair FERM_f0 (PF16511, IPR032425): N-terminal or F0 domain of Talin-head FERM |
24 |
TRAF1 | oncoprotein | 3 | 1.000 | 0 | HypA (PF01155, IPR000688): Hydrogenase/urease nickel incorporation, metallochaperone, hypA SlyX (PF04102, IPR007236): SlyX TRAF_BIRC3_bd (PF16673, IPR032070): TNF receptor-associated factor BIRC3 binding domain |
25 |
TRAF3IP1 | interactor | 2 | 1.000 | 0 | MIP-T3 (PF10243): Microtubule-binding protein MIP-T3 |
26 |
TRAF3IP3 | interactor | 1 | 0 | 0 | ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16) FUSC (PF04632, IPR006726): Fusaric acid resistance protein family HALZ (PF02183, IPR003106, SM00340): Homeobox associated leucine zipper BST2 (PF16716, IPR024886): Bone marrow stromal antigen 2 |
27 |
UBE2A | interactor | 7 | 0.667 | 3.333 | UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme |
28 |
UBE2B | interactor | 7 | 0.667 | 3.333 | UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme |
29 |
UBQLN4 | interactor | 4 | 1.000 | 0 | CRF (PF00473, IPR000187, SM00039): Corticotropin-releasing factor family DUF1180 (PF06679, IPR009565): Protein of unknown function (DUF1180) Arm_2 (PF04826, IPR006911): Armadillo-like NUDE_C (PF04880, IPR006964): NUDE protein, C-terminal conserved region UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain XPC-binding (PF09280, IPR015360): XPC-binding domain ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family Fur_reg_FbpB (PF13040, IPR025004): Fur-regulated basic protein B partial_CstF (PF15861, IPR031721): Partial cleavage stimulation factor domain |
30 |
UNK | interactor | 4 | 0.667 | 2.000 | MbeD_MobD (PF04899, IPR006983): MbeD/MobD like NUDE_C (PF04880, IPR006964): NUDE protein, C-terminal conserved region zf-CCCH (PF00642, IPR000571): Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF3450 (PF11932, IPR016866): Protein of unknown function (DUF3450) zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger) zf-CCCH_2 (PF14608): RNA-binding, Nab2-type zinc finger Torus (PF16131, IPR032297): Torus domain |
31 |
VCP | protein found in more fusions | 4 | 0.667 | 1.000 | AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA) CDC48_2 (PF02933, IPR004201, SM01072): Cell division protein 48 (CDC48), domain 2 CDC48_N (PF02359, IPR003338, SM01073): Cell division protein 48 (CDC48), N-terminal domain TniB (PF05621, IPR008868): Bacterial TniB protein Vps4_C (PF09336, IPR015415): Vps4 C terminal oligomerisation domain DUF3944 (PF13099, IPR025217): Domain of unknown function (DUF3944) |
32 |
VCPIP1 | interactor | 2 | 1.000 | 0 | ATP-synt_E (PF05680, IPR008386): ATP synthase E chain OTU (PF02338, IPR003323): OTU-like cysteine protease zf-C3H1 (PF10650, IPR019607, SM00356): Putative zinc-finger domain ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family SDP_N (PF12278, IPR022063): Sex determination protein N terminal |
33 |
ZDHHC17 | protein found in more fusions | 3 | 1.000 | 0 | zf-DHHC (PF01529, IPR001594): DHHC palmitoyltransferase Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_3 (PF13606, IPR002110): Ankyrin repeat Ank_4 (PF13637): Ankyrin repeats (many copies) |