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Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)298
The number (and %) of the onco-proteins101 (33.89 %)
The number (and %) of the tumor suppressors25 (8.39 %)
Total number of binary PPIs (saturation %)2617 (5.91 %)
The number (and %) of affected PPIs298 (11.39 %)
The number of possible different fusions55
PPI diameter2
PPI radius1
The average degree of PPI16.886
Assortativity coefficient-0.2475
The network average Clustering coefficient0.543
The number (and %) of a zero Clustering coefficients17 (5.70 %)
The number (and %) of a zero Betweenness Centrality54 (18.12 %)

ACTIVE INTERACTORS


List of the fusions

PPI for parental proteins: VHL All fusions
: CA391692;
Proteins found in more fusions ID3 (see 1 fusions); PSMB3 (see 1 fusions); VHL (see 1 fusions); PRDX1 (see 1 fusions); HIF1AN (see 1 fusions); EP300 (see 1 fusions); PLOD3 (see 2 fusions); COL4A2 (see 1 fusions); DDX5 (see 1 fusions); APP (see 4 fusions); HSP90AA1 (see 2 fusions); HNRNPLL (see 1 fusions); JAK2 (see 3 fusions); PLOD2 (see 1 fusions); COL4A1 (see 3 fusions); RBPMS (see 2 fusions); IMPDH2 (see 2 fusions); HNRNPD (see 1 fusions); FKBP8 (see 1 fusions); STUB1 (see 1 fusions); POLR2A (see 2 fusions); CSNK2A1 (see 1 fusions); DDX17 (see 3 fusions); EPAS1 (see 1 fusions); TGM2 (see 4 fusions); EGLN1 (see 1 fusions); NCL (see 3 fusions); PRKCD (see 2 fusions); IVNS1ABP (see 2 fusions); MYC (see 1 fusions); UBE2D2 (see 2 fusions); KAT2B (see 1 fusions); ACTB (see 2 fusions); COPS5 (see 1 fusions); RACK1/FN1 (see 1 fusions); PARP1 (see 1 fusions); UBC (see 1 fusions); CLU (see 5 fusions); TP53 (see 3 fusions); ALAS1 (see 1 fusions); PRKCH (see 1 fusions); MCM7 (see 2 fusions); CHMP2B (see 1 fusions); TRIM28 (see 1 fusions); RHOBTB3 (see 1 fusions); SP1 (see 1 fusions); HNRNPL (see 2 fusions); USP20 (see 1 fusions); UBR5 (see 4 fusions); RACK1 (see 3 fusions); RALYL (see 1 fusions); KAT5 (see 3 fusions); HNRNPC (see 1 fusions); PCGF2 (see 1 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 VHLparental protein2980.05061568.247Trypan_PARP (PF05887, IPR008882): Procyclic acidic repetitive protein (PARP)
VHL (PF01847, IPR022772): von Hippel-Lindau disease tumour suppressor protein
VHL_C (PF17211): VHL box domain
2 ACTBoncoprotein280.44452.113Actin (PF00022, IPR004000, SM00268): Actin
3 ADRB2interactor190.37344.8917tm_1 (PF00001, IPR000276): 7 transmembrane receptor (rhodopsin family)
4 AJUBAoncoprotein21.0000LIM (PF00412, IPR001781, SM00132): LIM domain
5 ALAS1protein found in more fusions31.0000Aminotran_1_2 (PF00155, IPR004839): Aminotransferase class I and II
Preseq_ALAS (PF09029, IPR015118): 5-aminolevulinate synthase presequence
6 ANKRD40interactor40.6670.167Ank_4 (PF13637): Ankyrin repeats (many copies)
Ank_5 (PF13857): Ankyrin repeats (many copies)
7 APPprotein found in more fusions550.112947.952APP_N (PF02177, IPR015849, SM00006): Amyloid A4 N-terminal heparin-binding
Beta-APP (PF03494, IPR013803): Beta-amyloid peptide (beta-APP)
BUD22 (PF09073, IPR015158): BUD22
IncA (PF04156, IPR007285): IncA protein
Kunitz_BPTI (PF00014, IPR002223, SM00131): Kunitz/Bovine pancreatic trypsin inhibitor domain
APP_amyloid (PF10515, IPR019543): beta-amyloid precursor protein C-terminus
APP_Cu_bd (PF12924, IPR011178): Copper-binding of amyloid precursor, CuBD
APP_E2 (PF12925, IPR024329): E2 domain of amyloid precursor protein
8 APRTinteractor30.6670.083Pribosyltran (PF00156, IPR000836): Phosphoribosyl transferase domain
9 ARoncoprotein280.248157.080Androgen_recep (PF02166, IPR001103): Androgen receptor
zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains)
Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
10 ASTLinteractor21.0000Astacin (PF01400, IPR001506): Astacin (Peptidase family M12A)
11 ATMoncoprotein180.36041.820FAT (PF02259, IPR003151): FAT domain
FATC (PF02260, IPR003152): FATC domain
HEAT (PF02985, IPR000357): HEAT repeat
PI3_PI4_kinase (PF00454, IPR000403, SM00146): Phosphatidylinositol 3- and 4-kinase
TAN (PF11640, IPR021668): Telomere-length maintenance and DNA damage repair
ANAPC5 (PF12862, IPR026000): Anaphase-promoting complex subunit 5
12 ATXN2interactor50.7000.872LsmAD (PF06741, IPR009604): LsmAD domain
PAM2 (PF07145, IPR009818): Ataxin-2 C-terminal region
DUF3446 (PF11928, IPR021849): Domain of unknown function (DUF3446)
Spt20 (PF12090, IPR021950): Spt20 family
SM-ATX (PF14438, IPR025852): Ataxin 2 SM domain
13 AURKAoncoprotein390.279219.696Pkinase (PF00069, IPR000719): Protein kinase domain
MTBP_C (PF14920, IPR029418): MDM2-binding
14 BCL2L11oncoprotein70.5242.450Bclx_interact (PF08945, IPR015040): Bcl-x interacting, BH3 domain
Bim_N (PF06773, IPR014771): Bim protein N-terminus
15 BCL2L14interactor21.0000Bcl-2 (PF00452, IPR026298): Apoptosis regulator proteins, Bcl-2 family
CF222 (PF15661, IPR031362): C6orf222, uncharacterised family
16 BSGinteractor70.28613.067Ig_2 (PF13895, IPR007110): Immunoglobulin domain
Ig_3 (PF13927): Immunoglobulin domain
Izumo-Ig (PF16706, IPR032699): Izumo-like Immunoglobulin domain
17 C1QBinteractor30.6671.000C1q (PF00386, IPR001073, SM00110): C1q domain
Collagen (PF01391, IPR008160): Collagen triple helix repeat (20 copies)
18 C1QTNF2interactor21.0000C1q (PF00386, IPR001073, SM00110): C1q domain
Collagen (PF01391, IPR008160): Collagen triple helix repeat (20 copies)
DUF1860 (PF08949, IPR015044): Domain of unknown function (DUF1860)
19 CAB39interactor50.5004.333Mo25 (PF08569, IPR013878): Mo25-like
20 CAPN7interactor100Calpain_III (PF01067, IPR022682, SM00720): Calpain large subunit, domain III
MIT (PF04212, IPR007330, SM00745): MIT (microtubule interacting and transport) domain
Peptidase_C2 (PF00648, IPR001300, SM00230): Calpain family cysteine protease
21 CAPZBinteractor80.6073.159Cytochrom_B562 (PF07361, IPR009155): Cytochrome b562
F_actin_cap_B (PF01115, IPR001698): F-actin capping protein, beta subunit
22 CARD9interactor31.0000CARD (PF00619, IPR001315, SM00114): Caspase recruitment domain
HALZ (PF02183, IPR003106, SM00340): Homeobox associated leucine zipper
IncA (PF04156, IPR007285): IncA protein
NPV_P10 (PF05531, IPR008702): Nucleopolyhedrovirus P10 protein
23 CBR1interactor40.6671.167adh_short (PF00106, IPR002198): short chain dehydrogenase
24 CBX1interactor60.7001.200Chromo (PF00385, IPR023780, SM00298): Chromo (CHRromatin Organisation MOdifier) domain
Chromo_shadow (PF01393, IPR008251, SM00300): Chromo shadow domain
25 CBX3interactor90.5006.540Chromo (PF00385, IPR023780, SM00298): Chromo (CHRromatin Organisation MOdifier) domain
DTHCT (PF08070, IPR012542): DTHCT (NUC029) region
Chromo_shadow (PF01393, IPR008251, SM00300): Chromo shadow domain
26 CBX5suppressor140.29537.045Chromo (PF00385, IPR023780, SM00298): Chromo (CHRromatin Organisation MOdifier) domain
Chromo_shadow (PF01393, IPR008251, SM00300): Chromo shadow domain
27 CCDC59interactor30.6670.500rRNA_processing (PF08524, IPR013730): rRNA processing
28 CCDC82interactor100RNA_pol_3_Rpc31 (PF11705, IPR024661): DNA-directed RNA polymerase III subunit Rpc31
Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal
DUF4196 (PF13846, IPR025244): Domain of unknown function (DUF4196)
DUF4211 (PF13926, IPR025451): Domain of unknown function (DUF4211)
29 CCT2interactor240.58333.952Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
30 CCT3interactor210.60034.048Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
31 CCT4interactor210.60519.896Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
32 CCT5interactor240.50758.271Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
33 CCT6Ainteractor180.70610.332Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
34 CCT7interactor200.59524.627Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
35 CCT8interactor190.7199.365Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
36 CD44oncoprotein70.4296.145VP4_2 (PF08935, IPR015031): Viral protein VP4 subunit
Xlink (PF00193, IPR000538, SM00445): Extracellular link domain
S36_mt (PF10937, IPR020373): Ribosomal protein S36, mitochondrial
37 CDC34oncoprotein90.6432.458UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
38 CDK2oncoprotein810.1851367.577Kdo (PF06293, IPR010440): Lipopolysaccharide kinase (Kdo/WaaP) family
Pkinase (PF00069, IPR000719): Protein kinase domain
39 CDKN2Aoncoprotein270.39076.119Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
Ank_5 (PF13857): Ankyrin repeats (many copies)
40 CDO1interactor100CDO_I (PF05995, IPR010300): Cysteine dioxygenase type I
41 CER1interactor31.0000DAN (PF03045, IPR004133): DAN domain
42 CERKLinteractor100DAGK_cat (PF00781, IPR001206, SM00046): Diacylglycerol kinase catalytic domain
43 CHEK2oncoprotein110.5338.295FHA (PF00498, IPR000253, SM00240): FHA domain
Pkinase (PF00069, IPR000719): Protein kinase domain
44 CHMP2Bprotein found in more fusions200Involucrin (PF00904, IPR000354): Involucrin repeat
Snf7 (PF03357, IPR005024): Snf7
45 CLUoncoprotein50.6670.310Clusterin (PF01093, IPR000753): Clusterin
46 CMC2interactor100Cmc1 (PF08583, IPR013892): Cytochrome c oxidase biogenesis protein Cmc1 like
Pet191_N (PF10203, IPR018793): Cytochrome c oxidase assembly protein PET191
47 CNTFinteractor31.0000CNTF (PF01110, IPR000151): Ciliary neurotrophic factor
48 COL4A1protein found in more fusions40.6671.000C4 (PF01413, IPR001442, SM00111): C-terminal tandem repeated domain in type 4 procollagen
Collagen (PF01391, IPR008160): Collagen triple helix repeat (20 copies)
DUF1860 (PF08949, IPR015044): Domain of unknown function (DUF1860)
49 COL4A2protein found in more fusions60.4006.000C4 (PF01413, IPR001442, SM00111): C-terminal tandem repeated domain in type 4 procollagen
Collagen (PF01391, IPR008160): Collagen triple helix repeat (20 copies)
DUF1860 (PF08949, IPR015044): Domain of unknown function (DUF1860)
50 COL4A3interactor100C4 (PF01413, IPR001442, SM00111): C-terminal tandem repeated domain in type 4 procollagen
Collagen (PF01391, IPR008160): Collagen triple helix repeat (20 copies)
DUF1860 (PF08949, IPR015044): Domain of unknown function (DUF1860)
51 COL4A5interactor21.0000C4 (PF01413, IPR001442, SM00111): C-terminal tandem repeated domain in type 4 procollagen
Collagen (PF01391, IPR008160): Collagen triple helix repeat (20 copies)
DUF1860 (PF08949, IPR015044): Domain of unknown function (DUF1860)
52 COL4A6interactor21.0000C4 (PF01413, IPR001442, SM00111): C-terminal tandem repeated domain in type 4 procollagen
Collagen (PF01391, IPR008160): Collagen triple helix repeat (20 copies)
53 COL6A1interactor21.0000Collagen (PF01391, IPR008160): Collagen triple helix repeat (20 copies)
VWA (PF00092, IPR002035, SM00327): von Willebrand factor type A domain
54 COL9A1interactor30.6671.000Collagen (PF01391, IPR008160): Collagen triple helix repeat (20 copies)
DUF826 (PF05696, IPR008544): Protein of unknown function (DUF826)
Laminin_G_2 (PF02210, IPR001791): Laminin G domain
55 COLGALT1interactor50.5002.900Glyco_transf_25 (PF01755, IPR002654): Glycosyltransferase family 25 (LPS biosynthesis protein)
Glyco_tranf_2_4 (PF13704): Glycosyl transferase family 2
56 COPS5protein found in more fusions930.2361270.114JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease
57 CRTAPinteractor21.0000Whi5 (PF08528, IPR013734): Whi5 like
YfiO (PF13525): Outer membrane lipoprotein
Stomagen (PF16851, IPR031753): Stomagen
58 CSNK2A1oncoprotein370.302176.679Pkinase (PF00069, IPR000719): Protein kinase domain
59 CSTBoncoprotein50.4004.900Cystatin (PF00031, IPR000010, SM00043): Cystatin domain
60 CSTF3interactor30.6670.143NRDE-2 (PF08424, IPR013633): NRDE-2, necessary for RNA interference
Suf (PF05843, IPR008847): Suppressor of forked protein (Suf)
TPR_6 (PF13174, IPR019734): Tetratricopeptide repeat
TPR_14 (PF13428): Tetratricopeptide repeat
TPR_19 (PF14559): Tetratricopeptide repeat
61 CUL2suppressor810.2261092.756Cullin (PF00888, IPR001373, SM00182): Cullin family
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
62 CUL5suppressor620.298417.501Cullin (PF00888, IPR001373, SM00182): Cullin family
GlutR_dimer (PF00745, IPR015896): Glutamyl-tRNAGlu reductase, dimerisation domain
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
63 CYBAinteractor30.6670.400Cytochrom_B558a (PF05038, IPR007732): Cytochrome Cytochrome b558 alpha-subunit
64 DACT1suppressor30.6670.500Dapper (PF15268, IPR024843): Dapper
65 DACT2interactor100Dapper (PF15268, IPR024843): Dapper
66 DCUN1D1interactor400.391158.809Cullin_binding (PF03556, IPR005176): Cullin binding
UBA_4 (PF14555): UBA-like domain
67 DDX17protein found in more fusions320.383102.200CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
Ferritin (PF00210, IPR008331): Ferritin-like domain
GRP (PF07172, IPR010800): Glycine rich protein family
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
68 DDX3Xsuppressor240.46745.628DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
DUF755 (PF05501, IPR008474): Domain of unknown function (DUF755)
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
69 DDX3Yinteractor100DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
70 DDX5oncoprotein300.44866.209DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
P68HR (PF08061, IPR012587): P68HR (NUC004) repeat
ResIII (PF04851, IPR006935): Type III restriction enzyme, res subunit
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
71 DGKIinteractor100Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain)
DAGK_acc (PF00609, IPR000756, SM00045): Diacylglycerol kinase accessory domain
DAGK_cat (PF00781, IPR001206, SM00046): Diacylglycerol kinase catalytic domain
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
Ank_4 (PF13637): Ankyrin repeats (many copies)
72 DGKZinteractor30.6671.000C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain)
DAGK_acc (PF00609, IPR000756, SM00045): Diacylglycerol kinase accessory domain
DAGK_cat (PF00781, IPR001206, SM00046): Diacylglycerol kinase catalytic domain
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
Ank_4 (PF13637): Ankyrin repeats (many copies)
73 DNAJA1interactor180.51629.958DnaJ (PF00226, IPR001623, SM00271): DnaJ domain
DnaJ_C (PF01556, IPR002939): DnaJ C terminal domain
74 DNAJA2interactor150.5819.412DnaJ (PF00226, IPR001623, SM00271): DnaJ domain
DnaJ_C (PF01556, IPR002939): DnaJ C terminal domain
75 DNAJA3suppressor110.49118.828DnaJ (PF00226, IPR001623, SM00271): DnaJ domain
DnaJ_C (PF01556, IPR002939): DnaJ C terminal domain
76 DVL2interactor100.44414.144DEP (PF00610, IPR000591, SM00049): Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP)
Dishevelled (PF02377, IPR003351): Dishevelled specific domain
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
DIX (PF00778, IPR001158, SM00021): DIX domain
Dsh_C (PF12316, IPR024580): Segment polarity protein dishevelled (Dsh) C terminal
77 E2F1oncoprotein170.47121.297Cellsynth_D (PF03500, IPR022798): Cellulose synthase subunit D
E2F_TDP (PF02319, IPR003316): E2F/DP family winged-helix DNA-binding domain
E2F_CC-MB (PF16421, IPR032198): E2F transcription factor CC-MB domain
78 EEF1B2interactor130.42413.400EF1_GNE (PF00736, IPR014038, SM00888): EF-1 guanine nucleotide exchange domain
EF-1_beta_acid (PF10587, IPR018940): Eukaryotic elongation factor 1 beta central acidic region
GST_C_6 (PF17171): Glutathione S-transferase, C-terminal domain
79 EGLN1oncoprotein130.25841.289zf-MYND (PF01753, IPR002893): MYND finger
2OG-FeII_Oxy_3 (PF13640, IPR005123): 2OG-Fe(II) oxygenase superfamily
80 EIF5Ainteractor70.6672.001EFP_N (PF08207, IPR013185): Elongation factor P (EF-P) KOW-like domain
eIF-5a (PF01287, IPR020189): Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold
81 EIF5A2interactor40.8330.500EFP_N (PF08207, IPR013185): Elongation factor P (EF-P) KOW-like domain
eIF-5a (PF01287, IPR020189): Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold
82 ELAVL1oncoprotein530.186690.671RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
83 EP300oncoprotein350.308169.143Creb_binding (PF09030, IPR014744): Creb binding
DUF902 (PF06001, IPR010303): Domain of Unknown Function (DUF902)
Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region
KIX (PF02172, IPR003101): KIX domain
RR_TM4-6 (PF06459, IPR009460): Ryanodine Receptor TM 4-6
TPX2 (PF06886, IPR027329): Targeting protein for Xklp2 (TPX2)
zf-TAZ (PF02135, IPR000197, SM00551): TAZ zinc finger
HAT_KAT11 (PF08214, IPR013178): Histone acetylation protein
Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type
84 EPAS1suppressor170.35031.332Corona_I (PF03187, IPR004876): Corona nucleocapsid I protein
HIF-1a_CTAD (PF08778, IPR014887): HIF-1 alpha C terminal transactivation domain
HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
PAS (PF00989, IPR013767, SM00091): PAS fold
HIF-1 (PF11413, IPR021537): Hypoxia-inducible factor-1
PAS_11 (PF14598): PAS domain
85 EPHA4interactor30.6670.400fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
Ephrin_rec_like (PF07699, IPR011641): Putative ephrin-receptor like
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
SAM_2 (PF07647, IPR011510): SAM domain (Sterile alpha motif)
DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369)
Ephrin_lbd (PF01404, IPR001090, SM00615): Ephrin receptor ligand binding domain
SusE (PF14292, IPR025970): SusE outer membrane protein
EphA2_TM (PF14575, IPR027936): Ephrin type-A receptor 2 transmembrane domain
86 EPORoncoprotein70.7142.919EpoR_lig-bind (PF09067, IPR015152): Erythropoietin receptor, ligand binding
fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
87 EXOSC8interactor50.8330.074RNase_PH (PF01138, IPR001247): 3' exoribonuclease family, domain 1
RNase_PH_C (PF03725, IPR015847): 3' exoribonuclease family, domain 2
88 FASTKD3interactor21.0000FAST_1 (PF06743, IPR010622): FAST kinase-like protein, subdomain 1
FAST_2 (PF08368, IPR013579): FAST kinase-like protein, subdomain 2
NUC205 (PF08168, IPR012584): NUC205 domain
RAP (PF08373, IPR013584, SM00952): RAP domain
89 FKBP8protein found in more fusions100.47210.669FKBP_C (PF00254, IPR001179): FKBP-type peptidyl-prolyl cis-trans isomerase
TPR_9 (PF13371, IPR011990): Tetratricopeptide repeat
TPR_16 (PF13432): Tetratricopeptide repeat
Fis1_TPR_C (PF14853, IPR028061): Fis1 C-terminal tetratricopeptide repeat
90 FLNAsuppressor170.36846.294CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
Filamin (PF00630, IPR017868): Filamin/ABP280 repeat
91 FN1oncoprotein970.1751916.994fn1 (PF00039, IPR000083, SM00058): Fibronectin type I domain
fn2 (PF00040, IPR000562, SM00059): Fibronectin type II domain
fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369)
92 FSCN1oncoprotein70.6193.387Fascin (PF06268, IPR022768): Fascin domain
93 FZR1suppressor80.39311.165WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
94 GLI1oncoprotein90.5286.682zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
FOXP-CC (PF16159, IPR032354): FOXP coiled-coil domain
95 GOLGA4interactor40.6670.917ACCA (PF03255, IPR001095): Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit
ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16)
DivIC (PF04977, IPR007060): Septum formation initiator
DUF106 (PF01956, IPR002809): Integral membrane protein DUF106
DUF16 (PF01519, IPR002862): Protein of unknown function DUF16
DUF641 (PF04859, IPR006943): Plant protein of unknown function (DUF641)
DUF724 (PF05266, IPR007930): Protein of unknown function (DUF724)
Fez1 (PF06818): Fez1
FlaC_arch (PF05377, IPR008039): Flagella accessory protein C (FlaC)
GRIP (PF01465, IPR000237, SM00755): GRIP domain
Mnd1 (PF03962, IPR005647): Mnd1 family
Pox_A_type_inc (PF04508, IPR007596): Viral A-type inclusion protein repeat
Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein
SlyX (PF04102, IPR007236): SlyX
Atg14 (PF10186, IPR018791): Vacuolar sorting 38 and autophagy-related subunit 14
XhlA (PF10779, IPR019715): Haemolysin XhlA
YlqD (PF11068, IPR021297): YlqD protein
ADIP (PF11559, IPR021622): Afadin- and alpha -actinin-Binding
DUF4407 (PF14362, IPR025519): Domain of unknown function (DUF4407)
CCDC-167 (PF15188, IPR028194): Coiled-coil domain-containing protein 167
PRKG1_interact (PF15898, IPR031775): cGMP-dependent protein kinase interacting domain
RecQ_Zn_bind (PF16124, IPR032284): RecQ zinc-binding
PKcGMP_CC (PF16808, IPR031831): Coiled-coil N-terminus of cGMP-dependent protein kinase
TetR_C_13 (PF16925, IPR011075): Bacterial transcriptional repressor C-terminal
96 GPLD1interactor31.0000FG-GAP (PF01839, IPR013517): FG-GAP repeat
Zn_dep_PLPC (PF00882, IPR029002, SM00770): Zinc dependent phospholipase C
97 GRNoncoprotein30.6670.500Granulin (PF00396, IPR000118, SM00277): Granulin
Lustrin_cystein (PF14625, IPR028150): Lustrin, cysteine-rich repeated domain
98 GRWD1interactor41.0000Voldacs (PF03517): Regulator of volume decrease after cellular swelling
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
CAF1C_H4-bd (PF12265, IPR022052): Histone-binding protein RBBP4 or subunit C of CAF1 complex
99 HAS1interactor100Glycos_transf_2 (PF00535, IPR001173): Glycosyl transferase family 2
Glyco_tranf_2_3 (PF13641): Glycosyltransferase like family 2
100 HDAC1suppressor430.266314.742FSAP_sig_propep (PF03032, IPR004275): Frog skin active peptide family signal and propeptide
Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
101 HDAC2oncoprotein260.35377.704Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
NARP1 (PF12569, IPR021183): NMDA receptor-regulated protein 1
102 HDAC3oncoprotein280.32873.691Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
103 HIF1Asuppressor430.216469.895Dicty_REP (PF05086, IPR007778): Dictyostelium (Slime Mold) REP protein
HIF-1a_CTAD (PF08778, IPR014887): HIF-1 alpha C terminal transactivation domain
HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
PAS (PF00989, IPR013767, SM00091): PAS fold
PAS_3 (PF08447, IPR013655): PAS fold
HIF-1 (PF11413, IPR021537): Hypoxia-inducible factor-1
104 HIF1ANprotein found in more fusions70.6670.860Cupin_8 (PF13621): Cupin-like domain
105 HIF3Ainteractor21.0000HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
PAS (PF00989, IPR013767, SM00091): PAS fold
Spo0M (PF07070, IPR009776): SpoOM protein
HIF-1 (PF11413, IPR021537): Hypoxia-inducible factor-1
PAS_11 (PF14598): PAS domain
106 HIST1H1Concoprotein90.6942.651Amelin (PF05111, IPR007798, SM00817): Ameloblastin precursor (Amelin)
Linker_histone (PF00538, IPR005818, SM00526): linker histone H1 and H5 family
DUF4349 (PF14257, IPR025645): Domain of unknown function (DUF4349)
107 HIST1H2BCinteractor21.0000Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
108 HIST1H2BLinteractor31.0000Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
109 HIST4H4interactor110.36414.455CENP-T_C (PF15511): Centromere kinetochore component CENP-T histone fold
110 HNRNPA1interactor570.349404.348RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
HnRNPA1 (PF11627, IPR021662): Nuclear factor hnRNPA1
111 HNRNPA2B1oncoprotein310.473102.650RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
112 HNRNPA3oncoprotein230.7836.272IATP (PF04568, IPR007648): Mitochondrial ATPase inhibitor, IATP
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
113 HNRNPABinteractor170.7943.131CBFNT (PF08143, IPR012956): CBFNT (NUC161) domain
GRP (PF07172, IPR010800): Glycine rich protein family
NID (PF07292, IPR009909): Nmi/IFP 35 domain (NID)
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
DUF2462 (PF09495, IPR019034): Protein of unknown function (DUF2462)
114 HNRNPCprotein found in more fusions260.45360.593APG6 (PF04111, IPR007243): Autophagy protein Apg6
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
SURF2 (PF05477, IPR008833): Surfeit locus protein 2 (SURF2)
115 HNRNPDoncoprotein380.416149.871CBFNT (PF08143, IPR012956): CBFNT (NUC161) domain
NID (PF07292, IPR009909): Nmi/IFP 35 domain (NID)
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
Keratin_2_head (PF16208, IPR032444): Keratin type II head
116 HNRNPDLinteractor240.70710.875CBFNT (PF08143, IPR012956): CBFNT (NUC161) domain
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
117 HNRNPH1oncoprotein330.56451.694RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
zf-RNPHF (PF08080, IPR012996): RNPHF zinc finger
118 HNRNPH2interactor230.64527.500RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
zf-RNPHF (PF08080, IPR012996): RNPHF zinc finger
119 HNRNPKoncoprotein380.470100.618ROKNT (PF08067, IPR012987): ROKNT (NUC014) domain
KH_1 (PF00013, IPR004088, SM00322): KH domain
120 HNRNPLprotein found in more fusions240.65618.087RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
Dscam_C (PF12355, IPR021012): Down syndrome cell adhesion molecule C terminal
RRM_5 (PF13893): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
121 HNRNPLLprotein found in more fusions50.5001.400RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
Limkain-b1 (PF11608, IPR024582): Limkain b1
RRM_5 (PF13893): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
122 HNRNPMinteractor360.53576.143RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
HnRNP_M (PF11532, IPR024666): Heterogeneous nuclear ribonucleoprotein M
Collagen_mid (PF15984, IPR031929): Bacterial collagen, middle region
123 HNRNPRinteractor310.51854.363RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
Limkain-b1 (PF11608, IPR024582): Limkain b1
124 HNRNPUinteractor650.377433.793CDC45 (PF02724, IPR003874): CDC45-like protein
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
SAP (PF02037, IPR003034, SM00513): SAP domain
SPRY (PF00622, IPR003877, SM00449): SPRY domain
AAA_33 (PF13671): AAA domain
WRNPLPNID (PF15017): Putative WW-binding domain and destruction box
125 HSP90AA1oncoprotein570.264601.792HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
HSP90 (PF00183, IPR001404): Hsp90 protein
126 HSPA1Ainteractor250.42367.141HSP70 (PF00012, IPR013126): Hsp70 protein
127 HSPA4interactor340.330133.261Herpes_ICP4_N (PF03584, IPR005206): Herpesvirus ICP4-like protein N-terminal region
HSP70 (PF00012, IPR013126): Hsp70 protein
TP53IP5 (PF15331, IPR029290): Cellular tumour antigen p53-inducible 5
128 HSPA5oncoprotein500.334364.687HSP70 (PF00012, IPR013126): Hsp70 protein
129 HSPA8oncoprotein410.311248.308HSP70 (PF00012, IPR013126): Hsp70 protein
130 IARSinteractor130.38521.437Anticodon_1 (PF08264, IPR013155): Anticodon-binding domain of tRNA
tRNA-synt_1 (PF00133, IPR002300): tRNA synthetases class I (I, L, M and V)
131 ID1interactor30.6670.667HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
132 ID2oncoprotein90.4646.168HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
133 ID3oncoprotein40.6670.250HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
134 ILF3oncoprotein460.429218.330dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif
DZF (PF07528, IPR006561, SM00572): DZF domain
135 IMPDH2protein found in more fusions100.4725.367IMPDH (PF00478, IPR001093): IMP dehydrogenase / GMP reductase domain
136 IREB2interactor21.0000Aconitase (PF00330, IPR001030): Aconitase family (aconitate hydratase)
Aconitase_C (PF00694, IPR000573): Aconitase C-terminal domain
137 IVNS1ABPprotein found in more fusions180.50711.228BACK (PF07707, IPR011705, SM00875): BTB And C-terminal Kelch
BTB (PF00651, IPR013069, SM00225): BTB/POZ domain
Kelch_1 (PF01344, IPR006652, SM00612): Kelch motif
138 JADE1interactor21.0000C1_2 (PF03107, IPR004146): C1 domain
Glyco_hydro_57 (PF03065, IPR004300): Glycosyl hydrolase family 57
EPL1 (PF10513, IPR019542): Enhancer of polycomb-like
eIF-5_eIF-2B (PF01873, IPR002735, SM00653): Domain found in IF2B/IF5
PHD_2 (PF13831): PHD-finger
zf-HC5HC2H_2 (PF13832): PHD-zinc-finger like domain
139 JAK2oncoprotein100.36116.033FERM_M (PF00373, IPR019748): FERM central domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
SH2 (PF00017, IPR000980, SM00252): SH2 domain
140 JMJD1Cinteractor21.0000ArfGap (PF01412, IPR001164, SM00105): Putative GTPase activating protein for Arf
JmjC (PF02373, IPR003347, SM00558): JmjC domain, hydroxylase
TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
zf-C5HC2 (PF02928, IPR004198): C5HC2 zinc finger
RbpA (PF13397, IPR025182): RNA polymerase-binding protein
141 KAT2Bprotein found in more fusions240.36867.732Acetyltransf_1 (PF00583, IPR000182): Acetyltransferase (GNAT) family
PCAF_N (PF06466, IPR009464): PCAF (P300/CBP-associated factor) N-terminal domain
Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
142 KAT5oncoprotein220.33376.864MOZ_SAS (PF01853, IPR002717): MOZ/SAS family
Tudor-knot (PF11717, IPR025995): RNA binding activity-knot of a chromodomain
143 KIF2Cinteractor60.6000.413Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family
Kinesin (PF00225, IPR001752, SM00129): Kinesin motor domain
144 KIF3Ainteractor40.8330.667Bacillus_HBL (PF05791, IPR008414): Bacillus haemolytic enterotoxin (HBL)
DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664)
Vfa1 (PF08432, IPR013640): AAA-ATPase Vps4-associated protein 1
DUF755 (PF05501, IPR008474): Domain of unknown function (DUF755)
Fez1 (PF06818): Fez1
Kinesin (PF00225, IPR001752, SM00129): Kinesin motor domain
DUF4200 (PF13863, IPR025252): Domain of unknown function (DUF4200)
145 KIF3Binteractor40.8330.667DUF948 (PF06103, IPR009293): Bacterial protein of unknown function (DUF948)
Kinesin (PF00225, IPR001752, SM00129): Kinesin motor domain
WRNPLPNID (PF15017): Putative WW-binding domain and destruction box
Kinesin_assoc (PF16183, IPR032405): Kinesin-associated
HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1
146 KIFAP3interactor60.4009.000KAP (PF05804): Kinesin-associated protein (KAP)
147 KIRREL2interactor21.0000C2-set_2 (PF08205, IPR013162): CD80-like C2-set immunoglobulin domain
I-set (PF07679, IPR013098): Immunoglobulin I-set domain
ig (PF00047, IPR013151, SM00409): Immunoglobulin domain
SepZ (PF06066, IPR009275): SepZ
Ig_3 (PF13927): Immunoglobulin domain
148 KLF4oncoprotein110.43610.647zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
149 KNG1interactor100Bradykinin (PF06753, IPR009608): Bradykinin
Chorion_2 (PF03964, IPR005649): Chorion family 2
Cystatin (PF00031, IPR000010, SM00043): Cystatin domain
150 KNTC1interactor30.6671.000DUF2240 (PF09999, IPR018716): Uncharacterized protein conserved in archaea (DUF2240)
MRP-S22 (PF10245, IPR019374): Mitochondrial 28S ribosomal protein S22
Rod_C (PF10493, IPR019527): Rough deal protein C-terminal region
151 LANCL1interactor21.0000LANC_like (PF05147, IPR007822): Lanthionine synthetase C-like protein
152 LIMD1oncoprotein70.5335.667LIM (PF00412, IPR001781, SM00132): LIM domain
153 LPPoncoprotein60.6672.944LIM (PF00412, IPR001781, SM00132): LIM domain
zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
154 LTV1interactor70.6191.133DUF1874 (PF08960, IPR015055): Domain of unknown function (DUF1874)
LTV (PF04180, IPR007307): Low temperature viability protein
155 MCConcoprotein70.33312.167ERM (PF00769, IPR011259): Ezrin/radixin/moesin family
IFP_35_N (PF07334, IPR009938): Interferon-induced 35 kDa protein (IFP 35) N-terminus
K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain
Mod_r (PF07200, IPR009851): Modifier of rudimentary (Mod(r)) protein
Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein
TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein
MCC-bdg_PDZ (PF10506, IPR019536): PDZ domain of MCC-2 bdg protein for Usher syndrome
TMF_DNA_bd (PF12329, IPR022092): TATA element modulatory factor 1 DNA binding
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
FAM76 (PF16046, IPR032017): FAM76 protein
156 MCM7protein found in more fusions170.40022.288MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family
MCM_N (PF14551, IPR027925): MCM N-terminal domain
MCM_OB (PF17207): MCM OB domain
157 MDFIinteractor100.25022.341MDFI (PF15316, IPR026134): MyoD family inhibitor
158 MIFoncoprotein120.49114.399MIF (PF01187, IPR001398): Macrophage migration inhibitory factor (MIF)
159 MKNK2interactor70.4297.137ABC_trans_aux (PF03886, IPR005586): ABC-type transport auxiliary lipoprotein component
Pkinase (PF00069, IPR000719): Protein kinase domain
160 MOB4interactor110.56420.000Mob1_phocein (PF03637, IPR005301): Mob1/phocein family
161 MSH4interactor21.0000MutS_II (PF05188, IPR007860): MutS domain II
MutS_V (PF00488, IPR000432, SM00534): MutS domain V
MutS_III (PF05192, IPR007696, SM00533): MutS domain III
162 MYBBP1Aoncoprotein220.45051.804DNA_pol_phi (PF04931, IPR007015): DNA polymerase phi
Pol_alpha_B_N (PF08418, IPR013627): DNA polymerase alpha subunit B N-terminal
163 MYConcoprotein650.192825.417HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
Myc-LZ (PF02344, IPR003327): Myc leucine zipper domain
Myc_N (PF01056, IPR012682): Myc amino-terminal region
164 MYL12Ainteractor40.6670.393EF-hand_11 (PF08976, IPR015070): EF-hand domain
DUF2267 (PF10025, IPR018727): Uncharacterized conserved protein (DUF2267)
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
165 NCLprotein found in more fusions400.409145.777DUF1754 (PF08555, IPR013865): Eukaryotic family of unknown function (DUF1754)
Myc_N (PF01056, IPR012682): Myc amino-terminal region
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
YL1 (PF05764, IPR008895): YL1 nuclear protein
Limkain-b1 (PF11608, IPR024582): Limkain b1
166 NEDD8interactor470.379189.753ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
167 NKRFinteractor50.9000.043dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif
G-patch (PF01585, IPR000467, SM00443): G-patch domain
R3H (PF01424, IPR001374, SM00393): R3H domain
XTBD (PF11952, IPR021859): XRN-Two Binding Domain, XTBD
168 NOB1interactor30.6670.154NOB1_Zn_bind (PF08772, IPR014881): Nin one binding (NOB1) Zn-ribbon like
WRNPLPNID (PF15017): Putative WW-binding domain and destruction box
PIN_6 (PF17146): PIN domain of ribonuclease
169 NR4A1suppressor110.5278.521zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains)
Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
170 OSR1interactor21.0000zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
171 P3H1interactor50.5004.067TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat
YfiO (PF13525): Outer membrane lipoprotein
2OG-FeII_Oxy_3 (PF13640, IPR005123): 2OG-Fe(II) oxygenase superfamily
MCM_N (PF14551, IPR027925): MCM N-terminal domain
Fis1_TPR_C (PF14853, IPR028061): Fis1 C-terminal tetratricopeptide repeat
172 PAPSS2interactor30.6670.250APS_kinase (PF01583, IPR002891): Adenylylsulphate kinase
ATP-sulfurylase (PF01747, IPR024951): ATP-sulfurylase
DUF258 (PF03193, IPR004881): Protein of unknown function, DUF258
YscJ_FliF (PF01514, IPR006182): Secretory protein of YscJ/FliF family
PUA_2 (PF14306, IPR025980): PUA-like domain
173 PARD3interactor70.4298.111PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
DUF3534 (PF12053, IPR021922): Domain of unknown function (DUF3534)
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
174 PARD6Ainteractor60.6004.900PB1 (PF00564, IPR000270, SM00666): PB1 domain
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
175 PARK7suppressor110.6446.598DJ-1_PfpI (PF01965, IPR002818): DJ-1/PfpI family
176 PARP1suppressor270.35772.490BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain
PADR1 (PF08063, IPR012982): PADR1 (NUC008) domain
PARP (PF00644, IPR012317): Poly(ADP-ribose) polymerase catalytic domain
PARP_reg (PF02877, IPR004102): Poly(ADP-ribose) polymerase, regulatory domain
WGR (PF05406, IPR008893, SM00773): WGR domain
zf-PARP (PF00645, IPR001510): Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region
177 PCGF2suppressor40.6670.143zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
RAWUL (PF16207, IPR032443): RAWUL domain RING finger- and WD40-associated ubiquitin-like
178 PCMT1interactor100.4898.315PCMT (PF01135, IPR000682): Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)
179 PDCD5suppressor40.6670.255dsDNA_bind (PF01984, IPR002836): Double-stranded DNA-binding domain
EF-1_beta_acid (PF10587, IPR018940): Eukaryotic elongation factor 1 beta central acidic region
180 PFASinteractor21.0000AIRS_C (PF02769, IPR010918): AIR synthase related protein, C-terminal domain
GATase_5 (PF13507): CobB/CobQ-like glutamine amidotransferase domain
181 PIAS4interactor130.37231.225CENP-B_dimeris (PF09026, IPR015115): Centromere protein B dimerisation domain
SAP (PF02037, IPR003034, SM00513): SAP domain
zf-MIZ (PF02891, IPR004181): MIZ/SP-RING zinc finger
PINIT (PF14324, IPR023321): PINIT domain
182 PIN1suppressor230.36482.703Rotamase (PF00639, IPR000297): PPIC-type PPIASE domain
WW (PF00397, IPR001202, SM00456): WW domain
183 PKD1L3interactor100GPS (PF01825, IPR000203, SM00303): GPCR proteolysis site, GPS, motif
PKD_channel (PF08016, IPR013122): Polycystin cation channel
PLAT (PF01477, IPR001024, SM00308): PLAT/LH2 domain
Lectin_C (PF00059, IPR001304, SM00034): Lectin C-type domain
184 PLD1oncoprotein31.0000PH (PF00169, IPR001849, SM00233): PH domain
PLDc (PF00614, IPR001736, SM00155): Phospholipase D Active site motif
PX (PF00787, IPR001683, SM00312): PX domain
PLDc_2 (PF13091, IPR025202): PLD-like domain
185 PLD2interactor50.5002.872PH (PF00169, IPR001849, SM00233): PH domain
PLDc (PF00614, IPR001736, SM00155): Phospholipase D Active site motif
PX (PF00787, IPR001683, SM00312): PX domain
PLDc_2 (PF13091, IPR025202): PLD-like domain
186 PLOD2protein found in more fusions70.5333.7732OG-FeII_Oxy (PF03171, IPR005123): 2OG-Fe(II) oxygenase superfamily
Anp1 (PF03452, IPR005109): Anp1
Glycos_transf_2 (PF00535, IPR001173): Glycosyl transferase family 2
187 PLOD3protein found in more fusions80.3816.2582OG-FeII_Oxy (PF03171, IPR005123): 2OG-Fe(II) oxygenase superfamily
Anp1 (PF03452, IPR005109): Anp1
188 POLR2Aprotein found in more fusions270.295126.536RNA_pol_Rpb1_1 (PF04997, IPR007080): RNA polymerase Rpb1, domain 1
RNA_pol_Rpb1_2 (PF00623, IPR000722): RNA polymerase Rpb1, domain 2
RNA_pol_Rpb1_3 (PF04983, IPR007066): RNA polymerase Rpb1, domain 3
RNA_pol_Rpb1_4 (PF05000, IPR007083): RNA polymerase Rpb1, domain 4
RNA_pol_Rpb1_5 (PF04998, IPR007081): RNA polymerase Rpb1, domain 5
RNA_pol_Rpb1_R (PF05001, IPR000684): RNA polymerase Rpb1 C-terminal repeat
189 POLR2Ginteractor41.0000SHS2_Rpb7-N (PF03876, IPR005576): SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397
S1 (PF00575, IPR003029, SM00316): S1 RNA binding domain
190 PPIBinteractor40.8330.500Pro_isomerase (PF00160, IPR002130): Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD
191 PPM1Binteractor40.5002.667PP2C (PF00481, IPR001932): Protein phosphatase 2C
PP2C_C (PF07830, IPR012911, SM00332): Protein serine/threonine phosphatase 2C, C-terminal domain
192 PRDX1oncoprotein140.5269.633AhpC-TSA (PF00578, IPR000866): AhpC/TSA family
1-cysPrx_C (PF10417, IPR019479): C-terminal domain of 1-Cys peroxiredoxin
193 PRKCDoncoprotein120.52710.356Pkinase (PF00069, IPR000719): Protein kinase domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain)
194 PRKCHprotein found in more fusions41.0000C2 (PF00168, IPR000008, SM00239): C2 domain
Pkinase (PF00069, IPR000719): Protein kinase domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain)
195 PRKCIinteractor80.46410.151PB1 (PF00564, IPR000270, SM00666): PB1 domain
Pkinase (PF00069, IPR000719): Protein kinase domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain)
196 PRKCZinteractor120.32727.908PB1 (PF00564, IPR000270, SM00666): PB1 domain
Pkinase (PF00069, IPR000719): Protein kinase domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain)
197 PRMT1interactor190.49025.197Methyltransf_25 (PF13649): Methyltransferase domain
198 PRMT3interactor70.5243.054PrmA (PF06325, IPR010456): Ribosomal protein L11 methyltransferase (PrmA)
zf-C2H2_2 (PF12756, IPR015880): C2H2 type zinc-finger (2 copies)
199 PRMT8interactor61.0000PrmA (PF06325, IPR010456): Ribosomal protein L11 methyltransferase (PrmA)
200 PSMB1interactor150.43827.853Proteasome (PF00227, IPR001353): Proteasome subunit
201 PSMB3protein found in more fusions90.7142.416Proteasome (PF00227, IPR001353): Proteasome subunit
202 PSMC3interactor140.43622.918AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA)
DUF3713 (PF12506, IPR022186): Protein of unknown function (DUF3713)
JIP_LZII (PF16471, IPR032486): JNK-interacting protein leucine zipper II
203 PSMD13interactor80.6434.169Mitovir_RNA_pol (PF05919, IPR008686): Mitovirus RNA-dependent RNA polymerase
PCI (PF01399, IPR000717, SM00088): PCI domain
204 PTPN14oncoprotein40.6670.157FERM_C (PF09380, IPR018980): FERM C-terminal PH-like domain
FERM_M (PF00373, IPR019748): FERM central domain
FERM_N (PF09379, IPR018979): FERM N-terminal domain
Y_phosphatase (PF00102, IPR000242, SM00194): Protein-tyrosine phosphatase
205 RAB1Boncoprotein30.6670.333Ras (PF00071, IPR001806, SM00173): Ras family
206 RACK1oncoprotein330.440123.804WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
207 RALYLprotein found in more fusions31.0000RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
TFIIIC_sub6 (PF10419, IPR019481): TFIIIC subunit
CENP-Q (PF13094, IPR025212): CENP-Q, a CENPA-CAD centromere complex subunit
208 RASGRP1oncoprotein30.6671.000bZIP_1 (PF00170, IPR004827): bZIP transcription factor
FlaC_arch (PF05377, IPR008039): Flagella accessory protein C (FlaC)
RasGEF (PF00617, IPR001895, SM00147): RasGEF domain
C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain)
EF-hand_1 (PF00036, IPR002048, SM00054): EF hand
RasGEF_N (PF00618, IPR000651, SM00229): RasGEF N-terminal motif
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
209 RB1CC1oncoprotein50.6002.139Arc_PepC_II (PF06847, IPR009655): Archaeal Peptidase A24 C-terminus Type II
DHC (PF09626, IPR018588): Dihaem cytochrome c
DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972)
FlaC_arch (PF05377, IPR008039): Flagella accessory protein C (FlaC)
ATG11 (PF10377, IPR019460): Autophagy-related protein 11
DUF4407 (PF14362, IPR025519): Domain of unknown function (DUF4407)
Jag_N (PF14804, IPR032782): Jag N-terminus
NPBW (PF15180, IPR013297): Neuropeptides B and W
HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1
BST2 (PF16716, IPR024886): Bone marrow stromal antigen 2
Goodbye (PF17109, IPR031350): fungal STAND N-terminal Goodbye domain
210 RBBP4oncoprotein180.37943.223eIF2A (PF08662, IPR013979): Eukaryotic translation initiation factor eIF2A
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Capsid_NCLDV (PF04451, IPR007542): Large eukaryotic DNA virus major capsid protein
CAF1C_H4-bd (PF12265, IPR022052): Histone-binding protein RBBP4 or subunit C of CAF1 complex
211 RBBP7oncoprotein110.56413.088WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Capsid_NCLDV (PF04451, IPR007542): Large eukaryotic DNA virus major capsid protein
CAF1C_H4-bd (PF12265, IPR022052): Histone-binding protein RBBP4 or subunit C of CAF1 complex
212 RBPMSprotein found in more fusions80.28611.056RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
213 RBPMS2interactor100RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
214 RBX1oncoprotein230.41656.997zf-rbx1 (PF12678, IPR024766): RING-H2 zinc finger domain
215 RHOBTB3protein found in more fusions80.4767.721BTB (PF00651, IPR013069, SM00225): BTB/POZ domain
Ras (PF00071, IPR001806, SM00173): Ras family
216 RHOConcoprotein21.0000Ras (PF00071, IPR001806, SM00173): Ras family
217 RIT1interactor100Ras (PF00071, IPR001806, SM00173): Ras family
218 RNF7oncoprotein120.47313.037zf-rbx1 (PF12678, IPR024766): RING-H2 zinc finger domain
Prok-RING_1 (PF14446): Prokaryotic RING finger family 1
219 RPA3interactor420.288179.989Rep_fac-A_3 (PF08661, IPR013970): Replication factor A protein 3
220 RPL10Ainteractor340.74727.010Ribosomal_L1 (PF00687, IPR028364): Ribosomal protein L1p/L10e family
221 RPL11suppressor380.69731.456Ribosomal_L5 (PF00281, IPR002132): Ribosomal protein L5
Ribosomal_L5_C (PF00673, IPR002132): ribosomal L5P family C-terminus
222 RPL12interactor380.70054.181Ribosomal_L11 (PF00298, IPR020783): Ribosomal protein L11, RNA binding domain
Ribosomal_L11_N (PF03946, IPR020784): Ribosomal protein L11, N-terminal domain
223 RPL14interactor340.76119.959KOW (PF00467, IPR005824, SM00739): KOW motif
Ribosomal_L14e (PF01929, IPR002784): Ribosomal protein L14
UPF0688 (PF15772, IPR031530): UPF0688 family
224 RPL18Ainteractor300.81410.286Ribosomal_L18A (PF01775, IPR023573): Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A
225 RPL21interactor340.77727.810Ribosomal_L21e (PF01157, IPR001147): Ribosomal protein L21e
226 RPL30interactor300.80720.479NCBP3 (PF10309, IPR019416): Nuclear cap-binding protein subunit 3
227 RPL5oncoprotein440.574125.929Ribosomal_L18_c (PF14204, IPR025607): Ribosomal L18 C-terminal region
Ribosomal_L5e (PF17144): Ribosomal large subunit proteins 60S L5, and 50S L18
228 RPL7Ainteractor340.67768.738Ribosomal_L7Ae (PF01248, IPR004038): Ribosomal protein L7Ae/L30e/S12e/Gadd45 family
229 RPLP0interactor430.59178.134Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
Ribosomal_L10 (PF00466, IPR001790): Ribosomal protein L10
230 RPS11interactor340.72423.780Ribosomal_S17 (PF00366, IPR000266): Ribosomal protein S17
Ribosomal_S17_N (PF16205, IPR032440): Ribosomal_S17 N-terminal
231 RPS14interactor340.78114.173Ribosomal_S11 (PF00411, IPR001971): Ribosomal protein S11
232 RPS15Ainteractor360.70633.194Ribosomal_S8 (PF00410, IPR000630): Ribosomal protein S8
233 RPS17interactor210.9051.348Ribosomal_S17e (PF00833, IPR001210): Ribosomal S17
234 RPS2interactor440.564142.957Ribosomal_S5 (PF00333, IPR013810): Ribosomal protein S5, N-terminal domain
Ribosomal_S5_C (PF03719, IPR005324): Ribosomal protein S5, C-terminal domain
235 RPS27interactor300.8486.648Ribosomal_S27e (PF01667, IPR000592): Ribosomal protein S27
DUF3795 (PF12675, IPR024227): Protein of unknown function (DUF3795)
236 RPS27Linteractor200.77410.494E7 (PF00527, IPR000148): E7 protein, Early protein
Ribosomal_S27e (PF01667, IPR000592): Ribosomal protein S27
zf-C2HC5 (PF06221, IPR009349): Putative zinc finger motif, C2HC5-type
DUF3382 (PF11862, IPR021807): Domain of unknown function (DUF3382)
237 RPS3interactor450.579106.594KH_2 (PF07650, IPR004044): KH domain
Ribosomal_S3_C (PF00189, IPR001351): Ribosomal protein S3, C-terminal domain
238 RPS3Ainteractor410.66840.722Ribosomal_S3Ae (PF01015, IPR001593): Ribosomal S3Ae family
239 RPS5interactor330.70826.098Ribosomal_S7 (PF00177, IPR023798): Ribosomal protein S7p/S5e
240 RPS6interactor390.69239.164Ribosomal_S6e (PF01092, IPR001377): Ribosomal protein S6e
DUF4574 (PF15141, IPR027896): Domain of unknown function (DUF4574)
241 RPS9interactor340.75817.940Ribosomal_S4 (PF00163, IPR001912): Ribosomal protein S4/S9 N-terminal domain
S4 (PF01479, IPR002942, SM00363): S4 domain
242 RPSAinteractor390.56897.144Ribosomal_S2 (PF00318, IPR001865): Ribosomal protein S2
40S_SA_C (PF16122, IPR032281): 40S ribosomal protein SA C-terminus
243 RWDD3interactor21.0000DUF1115 (PF06544, IPR010541): Protein of unknown function (DUF1115)
RWD (PF05773, IPR006575, SM00591): RWD domain
244 SAP130interactor80.5364.672SAP130_C (PF16014, IPR031963): Histone deacetylase complex subunit SAP130 C-terminus
245 SARNPoncoprotein40.5001.368SAP (PF02037, IPR003034, SM00513): SAP domain
HTH_Tnp_IS630 (PF01710, IPR002622): Transposase
Prok-E2_A (PF14457, IPR032865): Prokaryotic E2 family A
246 SAT2interactor50.8330.667Acetyltransf_1 (PF00583, IPR000182): Acetyltransferase (GNAT) family
247 SIRT1oncoprotein250.32698.274DUF592 (PF04574, IPR007654): Protein of unknown function (DUF592)
SIR2 (PF02146, IPR003000): Sir2 family
TPP_enzyme_M (PF00205, IPR012000): Thiamine pyrophosphate enzyme, central domain
248 SKP2oncoprotein210.34363.840LRR_1 (PF00560, IPR001611): Leucine Rich Repeat
LRR_2 (PF07723, IPR013101): Leucine Rich Repeat
LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies)
F-box-like (PF12937, IPR001810): F-box-like
LRR_6 (PF13516, IPR001611): Leucine Rich repeat
LRR_8 (PF13855, IPR001611): Leucine rich repeat
249 SLC2A1interactor21.0000Sugar_tr (PF00083, IPR005828): Sugar (and other) transporter
250 SLC3A2interactor50.6002.500Alpha-amylase (PF00128, IPR006047): Alpha amylase, catalytic domain
DUF3459 (PF11941, IPR022567): Domain of unknown function (DUF3459)
SLC3A2_N (PF16028, IPR031984): Solute carrier family 3 member 2 N-terminus
251 SNRNP70interactor190.59614.042RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
MIP-T3 (PF10243): Microtubule-binding protein MIP-T3
U1snRNP70_N (PF12220, IPR022023): U1 small nuclear ribonucleoprotein of 70kDa MW N terminal
252 SOCS1oncoprotein70.4766.352SH2 (PF00017, IPR000980, SM00252): SH2 domain
SOCS_box (PF07525, IPR001496): SOCS box
253 SOCS3suppressor110.36417.730SH2 (PF00017, IPR000980, SM00252): SH2 domain
SOCS_box (PF07525, IPR001496): SOCS box
254 SONinteractor50.4003.321Asp-B-Hydro_N (PF05279, IPR007943): Aspartyl beta-hydroxylase N-terminal region
G-patch (PF01585, IPR000467, SM00443): G-patch domain
tRNA_synt_1c_R2 (PF04557, IPR007638): Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2
Eapp_C (PF10238, IPR019370): E2F-associated phosphoprotein
DND1_DSRM (PF14709): double strand RNA binding domain from DEAD END PROTEIN 1
GREB1 (PF15782, IPR028422): Gene regulated by oestrogen in breast cancer
RSRP (PF17069): Arginine/Serine-Rich protein 1
255 SP1protein found in more fusions290.339117.106zf-Di19 (PF05605, IPR008598): Drought induced 19 protein (Di19), zinc-binding
Herpes_capsid (PF06112, IPR009299): Gammaherpesvirus capsid protein
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
Miga (PF10265, IPR019392): Mitoguardin
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
256 SPRY2suppressor100.25025.000KAR9 (PF08580, IPR013889): Yeast cortical protein KAR9
Sprouty (PF05210, IPR007875): Sprouty protein (Spry)
257 STK16interactor50.5003.000Pkinase (PF00069, IPR000719): Protein kinase domain
258 STK38interactor40.6670.286MEKHLA (PF08670, IPR013978): MEKHLA domain
Pkinase (PF00069, IPR000719): Protein kinase domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
259 STUB1suppressor240.33276.618U-box (PF04564, IPR003613, SM00504): U-box domain
ANAPC3 (PF12895): Anaphase-promoting complex, cyclosome, subunit 3
TPR_11 (PF13414, IPR011990): TPR repeat
TPR_20 (PF14561): Tetratricopeptide repeat
260 TAGLN2interactor100.42210.050Calponin (PF00402, IPR000557): Calponin family repeat
CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
261 TARDBPinteractor530.397217.880RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
262 TARSinteractor90.38912.296HGTP_anticodon (PF03129, IPR004154): Anticodon binding domain
TGS (PF02824, IPR004095): TGS domain
tRNA-synt_2b (PF00587, IPR002314): tRNA synthetase class II core domain (G, H, P, S and T)
tRNA_SAD (PF07973, IPR012947, SM00863): Threonyl and Alanyl tRNA synthetase second additional domain
263 TCEB1interactor270.262166.689Skp1_POZ (PF03931, IPR016073): Skp1 family, tetramerisation domain
264 TCEB2interactor220.33881.501ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
265 TCEB3suppressor70.4768.900Elongin_A (PF06881, IPR010684): RNA polymerase II transcription factor SIII (Elongin) subunit A
Med26 (PF08711, IPR017923): TFIIS helical bundle-like domain
266 TCP1interactor220.61522.846Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
267 TGFB1I1interactor21.0000LIM (PF00412, IPR001781, SM00132): LIM domain
Paxillin (PF03535): Paxillin family
268 TGM2protein found in more fusions120.34525.419Transglut_C (PF00927, IPR008958): Transglutaminase family, C-terminal ig like domain
Transglut_N (PF00868, IPR001102): Transglutaminase family
Transglut_core (PF01841, IPR002931, SM00460): Transglutaminase-like superfamily
269 TOP2Aoncoprotein170.42623.808DNA_gyraseB (PF00204, IPR013506): DNA gyrase B
DTHCT (PF08070, IPR012542): DTHCT (NUC029) region
HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
Sec62 (PF03839, IPR004728): Translocation protein Sec62
Toprim (PF01751, IPR006171, SM00493): Toprim domain
DNA_topoisoIV (PF00521, IPR002205, SM00434): DNA gyrase/topoisomerase IV, subunit A
PHC2_SAM_assoc (PF16616): Unstructured region on Polyhomeotic-like protein 1 and 2
TOPRIM_C (PF16898, IPR031660): C-terminal associated domain of TOPRIM
270 TP53oncoprotein1010.1732140.709DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region
P53 (PF00870, IPR011615): P53 DNA-binding domain
P53_tetramer (PF07710, IPR010991): P53 tetramerisation motif
271 TPT1interactor40.6670.183TCTP (PF00838, IPR018105): Translationally controlled tumour protein
272 TRAFD1interactor31.0000zf-Di19 (PF05605, IPR008598): Drought induced 19 protein (Di19), zinc-binding
DM (PF00751, IPR001275, SM00301): DM DNA binding domain
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-C2H2_4 (PF13894): C2H2-type zinc finger
zf-C2HC_2 (PF13913): zinc-finger of a C2HC-type
273 TRIM28protein found in more fusions360.277232.137ASFV_J13L (PF05568, IPR008385): African swine fever virus J13L protein
K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain
PHD (PF00628, IPR019787, SM00249): PHD-finger
FYVE_2 (PF02318, IPR010911): FYVE-type zinc finger
zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger
zf-RING_5 (PF14634, IPR001841): zinc-RING finger domain
SKA2 (PF16740, IPR026762): Spindle and kinetochore-associated protein 2
274 TRIP12interactor60.5331.752Alpha_GJ (PF03229, IPR004913): Alphavirus glycoprotein J
Ndc1_Nup (PF09531, IPR019049): Nucleoporin protein Ndc1-Nup
WWE (PF02825, IPR004170, SM00678): WWE domain
SOG2 (PF10428, IPR019487): RAM signalling pathway protein
HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
UNC45-central (PF11701, IPR024660): Myosin-binding striated muscle assembly central
HEAT_2 (PF13646): HEAT repeats
275 TUBA1Aoncoprotein120.51511.149Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain
Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain
276 TUBA3Cinteractor50.7000.887Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain
Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain
277 TUBA3Dinteractor40.5000.476Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain
Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain
278 TUBA3Einteractor50.7002.000Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain
Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain
279 TUBA4Ainteractor150.6386.698Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain
Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain
280 TUBB4Binteractor210.37647.400Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain
Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain
281 TXNoncoprotein110.5458.258Thioredoxin (PF00085, IPR013766): Thioredoxin
282 UBCprotein found in more fusions680.1781088.932ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
283 UBE2D1interactor160.40030.379UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
284 UBE2D2oncoprotein130.40920.660UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
285 UBR5protein found in more fusions80.6673.219CENP-B_dimeris (PF09026, IPR015115): Centromere protein B dimerisation domain
SDA1 (PF05285, IPR007949): SDA1
HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
PABP (PF00658, IPR002004, SM00517): Poly-adenylate binding protein, unique domain
E3_UbLigase_EDD (PF11547, IPR024725): E3 ubiquitin ligase EDD
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
DUF3915 (PF13054, IPR025026): Protein of unknown function (DUF3915)
RCDG1 (PF15725, IPR031457): Renal cancer differentiation gene 1 protein
286 UBXN7interactor130.52617.545UBX (PF00789, IPR001012, SM00166): UBX domain
UIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif
Thioredoxin_7 (PF13899): Thioredoxin-like
UBA_4 (PF14555): UBA-like domain
287 USP20protein found in more fusions90.35715.633UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase
zf-UBP (PF02148, IPR001607, SM00290): Zn-finger in ubiquitin-hydrolases and other protein
DUSP (PF06337, IPR006615, SM00695): DUSP domain
288 USP33suppressor90.4179.568UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase
zf-UBP (PF02148, IPR001607, SM00290): Zn-finger in ubiquitin-hydrolases and other protein
DUSP (PF06337, IPR006615, SM00695): DUSP domain
289 UXTinteractor30.6670.400Prefoldin (PF02996, IPR004127): Prefoldin subunit
290 VAPBinteractor60.6004.233ATP-synt_G (PF04718, IPR006808): Mitochondrial ATP synthase g subunit
ZapB (PF06005, IPR009252): Cell division protein ZapB
Motile_Sperm (PF00635, IPR000535): MSP (Major sperm protein) domain
291 VBP1interactor80.25016.319Prefoldin (PF02996, IPR004127): Prefoldin subunit
292 WTIPinteractor100DUF983 (PF06170, IPR009325): Protein of unknown function (DUF983)
LIM (PF00412, IPR001781, SM00132): LIM domain
293 XRCC5suppressor200.41527.274Ku (PF02735, IPR006164, SM00559): Ku70/Ku80 beta-barrel domain
Ku_C (PF03730, IPR005160): Ku70/Ku80 C-terminal arm
Ku_N (PF03731, IPR005161): Ku70/Ku80 N-terminal alpha/beta domain
Ku_PK_bind (PF08785, IPR014893): Ku C terminal domain like
294 YY1AP1interactor100CtnDOT_TraJ (PF07863, IPR012424): Homologues of TraJ from Bacteroides conjugative transposon
JAKMIP_CC3 (PF16034, IPR031994): JAKMIP CC3 domain
295 ZNF197interactor31.0000KRAB (PF01352, IPR001909, SM00349): KRAB box
SCAN (PF02023, IPR003309, SM00431): SCAN domain
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger
296 ZNF350interactor30.6670.143KRAB (PF01352, IPR001909, SM00349): KRAB box
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
297 ZNF512Binteractor60.5333.117YTV (PF07639, IPR011521): YTV
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-C2HC5 (PF06221, IPR009349): Putative zinc finger motif, C2HC5-type
zf-Nse (PF11789, IPR004181): Zinc-finger of the MIZ type in Nse subunit
Zn_Tnp_IS1595 (PF12760, IPR024442): Transposase zinc-ribbon domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger
zf-C2H2_aberr (PF17017, IPR031514): Aberrant zinc-finger
298 ZYXsuppressor70.4297.242DUF1180 (PF06679, IPR009565): Protein of unknown function (DUF1180)
LIM (PF00412, IPR001781, SM00132): LIM domain
DUF2757 (PF10955, IPR020115): Protein of unknown function (DUF2757)

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