1 |
VHL | parental protein | 298 | 0.050 | 61568.247 | Trypan_PARP (PF05887, IPR008882): Procyclic acidic repetitive protein (PARP) VHL (PF01847, IPR022772): von Hippel-Lindau disease tumour suppressor protein VHL_C (PF17211): VHL box domain |
2 |
ACTB | oncoprotein | 28 | 0.444 | 52.113 | Actin (PF00022, IPR004000, SM00268): Actin |
3 |
ADRB2 | interactor | 19 | 0.373 | 44.891 | 7tm_1 (PF00001, IPR000276): 7 transmembrane receptor (rhodopsin family) |
4 |
AJUBA | oncoprotein | 2 | 1.000 | 0 | LIM (PF00412, IPR001781, SM00132): LIM domain |
5 |
ALAS1 | protein found in more fusions | 3 | 1.000 | 0 | Aminotran_1_2 (PF00155, IPR004839): Aminotransferase class I and II Preseq_ALAS (PF09029, IPR015118): 5-aminolevulinate synthase presequence |
6 |
ANKRD40 | interactor | 4 | 0.667 | 0.167 | Ank_4 (PF13637): Ankyrin repeats (many copies) Ank_5 (PF13857): Ankyrin repeats (many copies) |
7 |
APP | protein found in more fusions | 55 | 0.112 | 947.952 | APP_N (PF02177, IPR015849, SM00006): Amyloid A4 N-terminal heparin-binding Beta-APP (PF03494, IPR013803): Beta-amyloid peptide (beta-APP) BUD22 (PF09073, IPR015158): BUD22 IncA (PF04156, IPR007285): IncA protein Kunitz_BPTI (PF00014, IPR002223, SM00131): Kunitz/Bovine pancreatic trypsin inhibitor domain APP_amyloid (PF10515, IPR019543): beta-amyloid precursor protein C-terminus APP_Cu_bd (PF12924, IPR011178): Copper-binding of amyloid precursor, CuBD APP_E2 (PF12925, IPR024329): E2 domain of amyloid precursor protein |
8 |
APRT | interactor | 3 | 0.667 | 0.083 | Pribosyltran (PF00156, IPR000836): Phosphoribosyl transferase domain |
9 |
AR | oncoprotein | 28 | 0.248 | 157.080 | Androgen_recep (PF02166, IPR001103): Androgen receptor zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor |
10 |
ASTL | interactor | 2 | 1.000 | 0 | Astacin (PF01400, IPR001506): Astacin (Peptidase family M12A) |
11 |
ATM | oncoprotein | 18 | 0.360 | 41.820 | FAT (PF02259, IPR003151): FAT domain FATC (PF02260, IPR003152): FATC domain HEAT (PF02985, IPR000357): HEAT repeat PI3_PI4_kinase (PF00454, IPR000403, SM00146): Phosphatidylinositol 3- and 4-kinase TAN (PF11640, IPR021668): Telomere-length maintenance and DNA damage repair ANAPC5 (PF12862, IPR026000): Anaphase-promoting complex subunit 5 |
12 |
ATXN2 | interactor | 5 | 0.700 | 0.872 | LsmAD (PF06741, IPR009604): LsmAD domain PAM2 (PF07145, IPR009818): Ataxin-2 C-terminal region DUF3446 (PF11928, IPR021849): Domain of unknown function (DUF3446) Spt20 (PF12090, IPR021950): Spt20 family SM-ATX (PF14438, IPR025852): Ataxin 2 SM domain |
13 |
AURKA | oncoprotein | 39 | 0.279 | 219.696 | Pkinase (PF00069, IPR000719): Protein kinase domain MTBP_C (PF14920, IPR029418): MDM2-binding |
14 |
BCL2L11 | oncoprotein | 7 | 0.524 | 2.450 | Bclx_interact (PF08945, IPR015040): Bcl-x interacting, BH3 domain Bim_N (PF06773, IPR014771): Bim protein N-terminus |
15 |
BCL2L14 | interactor | 2 | 1.000 | 0 | Bcl-2 (PF00452, IPR026298): Apoptosis regulator proteins, Bcl-2 family CF222 (PF15661, IPR031362): C6orf222, uncharacterised family |
16 |
BSG | interactor | 7 | 0.286 | 13.067 | Ig_2 (PF13895, IPR007110): Immunoglobulin domain Ig_3 (PF13927): Immunoglobulin domain Izumo-Ig (PF16706, IPR032699): Izumo-like Immunoglobulin domain |
17 |
C1QB | interactor | 3 | 0.667 | 1.000 | C1q (PF00386, IPR001073, SM00110): C1q domain Collagen (PF01391, IPR008160): Collagen triple helix repeat (20 copies) |
18 |
C1QTNF2 | interactor | 2 | 1.000 | 0 | C1q (PF00386, IPR001073, SM00110): C1q domain Collagen (PF01391, IPR008160): Collagen triple helix repeat (20 copies) DUF1860 (PF08949, IPR015044): Domain of unknown function (DUF1860) |
19 |
CAB39 | interactor | 5 | 0.500 | 4.333 | Mo25 (PF08569, IPR013878): Mo25-like |
20 |
CAPN7 | interactor | 1 | 0 | 0 | Calpain_III (PF01067, IPR022682, SM00720): Calpain large subunit, domain III MIT (PF04212, IPR007330, SM00745): MIT (microtubule interacting and transport) domain Peptidase_C2 (PF00648, IPR001300, SM00230): Calpain family cysteine protease |
21 |
CAPZB | interactor | 8 | 0.607 | 3.159 | Cytochrom_B562 (PF07361, IPR009155): Cytochrome b562 F_actin_cap_B (PF01115, IPR001698): F-actin capping protein, beta subunit |
22 |
CARD9 | interactor | 3 | 1.000 | 0 | CARD (PF00619, IPR001315, SM00114): Caspase recruitment domain HALZ (PF02183, IPR003106, SM00340): Homeobox associated leucine zipper IncA (PF04156, IPR007285): IncA protein NPV_P10 (PF05531, IPR008702): Nucleopolyhedrovirus P10 protein |
23 |
CBR1 | interactor | 4 | 0.667 | 1.167 | adh_short (PF00106, IPR002198): short chain dehydrogenase |
24 |
CBX1 | interactor | 6 | 0.700 | 1.200 | Chromo (PF00385, IPR023780, SM00298): Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow (PF01393, IPR008251, SM00300): Chromo shadow domain |
25 |
CBX3 | interactor | 9 | 0.500 | 6.540 | Chromo (PF00385, IPR023780, SM00298): Chromo (CHRromatin Organisation MOdifier) domain DTHCT (PF08070, IPR012542): DTHCT (NUC029) region Chromo_shadow (PF01393, IPR008251, SM00300): Chromo shadow domain |
26 |
CBX5 | suppressor | 14 | 0.295 | 37.045 | Chromo (PF00385, IPR023780, SM00298): Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow (PF01393, IPR008251, SM00300): Chromo shadow domain |
27 |
CCDC59 | interactor | 3 | 0.667 | 0.500 | rRNA_processing (PF08524, IPR013730): rRNA processing |
28 |
CCDC82 | interactor | 1 | 0 | 0 | RNA_pol_3_Rpc31 (PF11705, IPR024661): DNA-directed RNA polymerase III subunit Rpc31 Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal DUF4196 (PF13846, IPR025244): Domain of unknown function (DUF4196) DUF4211 (PF13926, IPR025451): Domain of unknown function (DUF4211) |
29 |
CCT2 | interactor | 24 | 0.583 | 33.952 | Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family |
30 |
CCT3 | interactor | 21 | 0.600 | 34.048 | Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family |
31 |
CCT4 | interactor | 21 | 0.605 | 19.896 | Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family |
32 |
CCT5 | interactor | 24 | 0.507 | 58.271 | Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family |
33 |
CCT6A | interactor | 18 | 0.706 | 10.332 | Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family |
34 |
CCT7 | interactor | 20 | 0.595 | 24.627 | Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family |
35 |
CCT8 | interactor | 19 | 0.719 | 9.365 | Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family |
36 |
CD44 | oncoprotein | 7 | 0.429 | 6.145 | VP4_2 (PF08935, IPR015031): Viral protein VP4 subunit Xlink (PF00193, IPR000538, SM00445): Extracellular link domain S36_mt (PF10937, IPR020373): Ribosomal protein S36, mitochondrial |
37 |
CDC34 | oncoprotein | 9 | 0.643 | 2.458 | UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme |
38 |
CDK2 | oncoprotein | 81 | 0.185 | 1367.577 | Kdo (PF06293, IPR010440): Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase (PF00069, IPR000719): Protein kinase domain |
39 |
CDKN2A | oncoprotein | 27 | 0.390 | 76.119 | Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_5 (PF13857): Ankyrin repeats (many copies) |
40 |
CDO1 | interactor | 1 | 0 | 0 | CDO_I (PF05995, IPR010300): Cysteine dioxygenase type I |
41 |
CER1 | interactor | 3 | 1.000 | 0 | DAN (PF03045, IPR004133): DAN domain |
42 |
CERKL | interactor | 1 | 0 | 0 | DAGK_cat (PF00781, IPR001206, SM00046): Diacylglycerol kinase catalytic domain |
43 |
CHEK2 | oncoprotein | 11 | 0.533 | 8.295 | FHA (PF00498, IPR000253, SM00240): FHA domain Pkinase (PF00069, IPR000719): Protein kinase domain |
44 |
CHMP2B | protein found in more fusions | 2 | 0 | 0 | Involucrin (PF00904, IPR000354): Involucrin repeat Snf7 (PF03357, IPR005024): Snf7 |
45 |
CLU | oncoprotein | 5 | 0.667 | 0.310 | Clusterin (PF01093, IPR000753): Clusterin |
46 |
CMC2 | interactor | 1 | 0 | 0 | Cmc1 (PF08583, IPR013892): Cytochrome c oxidase biogenesis protein Cmc1 like Pet191_N (PF10203, IPR018793): Cytochrome c oxidase assembly protein PET191 |
47 |
CNTF | interactor | 3 | 1.000 | 0 | CNTF (PF01110, IPR000151): Ciliary neurotrophic factor |
48 |
COL4A1 | protein found in more fusions | 4 | 0.667 | 1.000 | C4 (PF01413, IPR001442, SM00111): C-terminal tandem repeated domain in type 4 procollagen Collagen (PF01391, IPR008160): Collagen triple helix repeat (20 copies) DUF1860 (PF08949, IPR015044): Domain of unknown function (DUF1860) |
49 |
COL4A2 | protein found in more fusions | 6 | 0.400 | 6.000 | C4 (PF01413, IPR001442, SM00111): C-terminal tandem repeated domain in type 4 procollagen Collagen (PF01391, IPR008160): Collagen triple helix repeat (20 copies) DUF1860 (PF08949, IPR015044): Domain of unknown function (DUF1860) |
50 |
COL4A3 | interactor | 1 | 0 | 0 | C4 (PF01413, IPR001442, SM00111): C-terminal tandem repeated domain in type 4 procollagen Collagen (PF01391, IPR008160): Collagen triple helix repeat (20 copies) DUF1860 (PF08949, IPR015044): Domain of unknown function (DUF1860) |
51 |
COL4A5 | interactor | 2 | 1.000 | 0 | C4 (PF01413, IPR001442, SM00111): C-terminal tandem repeated domain in type 4 procollagen Collagen (PF01391, IPR008160): Collagen triple helix repeat (20 copies) DUF1860 (PF08949, IPR015044): Domain of unknown function (DUF1860) |
52 |
COL4A6 | interactor | 2 | 1.000 | 0 | C4 (PF01413, IPR001442, SM00111): C-terminal tandem repeated domain in type 4 procollagen Collagen (PF01391, IPR008160): Collagen triple helix repeat (20 copies) |
53 |
COL6A1 | interactor | 2 | 1.000 | 0 | Collagen (PF01391, IPR008160): Collagen triple helix repeat (20 copies) VWA (PF00092, IPR002035, SM00327): von Willebrand factor type A domain |
54 |
COL9A1 | interactor | 3 | 0.667 | 1.000 | Collagen (PF01391, IPR008160): Collagen triple helix repeat (20 copies) DUF826 (PF05696, IPR008544): Protein of unknown function (DUF826) Laminin_G_2 (PF02210, IPR001791): Laminin G domain |
55 |
COLGALT1 | interactor | 5 | 0.500 | 2.900 | Glyco_transf_25 (PF01755, IPR002654): Glycosyltransferase family 25 (LPS biosynthesis protein) Glyco_tranf_2_4 (PF13704): Glycosyl transferase family 2 |
56 |
COPS5 | protein found in more fusions | 93 | 0.236 | 1270.114 | JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease |
57 |
CRTAP | interactor | 2 | 1.000 | 0 | Whi5 (PF08528, IPR013734): Whi5 like YfiO (PF13525): Outer membrane lipoprotein Stomagen (PF16851, IPR031753): Stomagen |
58 |
CSNK2A1 | oncoprotein | 37 | 0.302 | 176.679 | Pkinase (PF00069, IPR000719): Protein kinase domain |
59 |
CSTB | oncoprotein | 5 | 0.400 | 4.900 | Cystatin (PF00031, IPR000010, SM00043): Cystatin domain |
60 |
CSTF3 | interactor | 3 | 0.667 | 0.143 | NRDE-2 (PF08424, IPR013633): NRDE-2, necessary for RNA interference Suf (PF05843, IPR008847): Suppressor of forked protein (Suf) TPR_6 (PF13174, IPR019734): Tetratricopeptide repeat TPR_14 (PF13428): Tetratricopeptide repeat TPR_19 (PF14559): Tetratricopeptide repeat |
61 |
CUL2 | suppressor | 81 | 0.226 | 1092.756 | Cullin (PF00888, IPR001373, SM00182): Cullin family Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain |
62 |
CUL5 | suppressor | 62 | 0.298 | 417.501 | Cullin (PF00888, IPR001373, SM00182): Cullin family GlutR_dimer (PF00745, IPR015896): Glutamyl-tRNAGlu reductase, dimerisation domain Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain |
63 |
CYBA | interactor | 3 | 0.667 | 0.400 | Cytochrom_B558a (PF05038, IPR007732): Cytochrome Cytochrome b558 alpha-subunit |
64 |
DACT1 | suppressor | 3 | 0.667 | 0.500 | Dapper (PF15268, IPR024843): Dapper |
65 |
DACT2 | interactor | 1 | 0 | 0 | Dapper (PF15268, IPR024843): Dapper |
66 |
DCUN1D1 | interactor | 40 | 0.391 | 158.809 | Cullin_binding (PF03556, IPR005176): Cullin binding UBA_4 (PF14555): UBA-like domain |
67 |
DDX17 | protein found in more fusions | 32 | 0.383 | 102.200 | CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal DEAD (PF00270, IPR011545): DEAD/DEAH box helicase Ferritin (PF00210, IPR008331): Ferritin-like domain GRP (PF07172, IPR010800): Glycine rich protein family Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain |
68 |
DDX3X | suppressor | 24 | 0.467 | 45.628 | DEAD (PF00270, IPR011545): DEAD/DEAH box helicase DUF755 (PF05501, IPR008474): Domain of unknown function (DUF755) Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain |
69 |
DDX3Y | interactor | 1 | 0 | 0 | DEAD (PF00270, IPR011545): DEAD/DEAH box helicase Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain |
70 |
DDX5 | oncoprotein | 30 | 0.448 | 66.209 | DEAD (PF00270, IPR011545): DEAD/DEAH box helicase P68HR (PF08061, IPR012587): P68HR (NUC004) repeat ResIII (PF04851, IPR006935): Type III restriction enzyme, res subunit Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain |
71 |
DGKI | interactor | 1 | 0 | 0 | Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain) DAGK_acc (PF00609, IPR000756, SM00045): Diacylglycerol kinase accessory domain DAGK_cat (PF00781, IPR001206, SM00046): Diacylglycerol kinase catalytic domain Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_4 (PF13637): Ankyrin repeats (many copies) |
72 |
DGKZ | interactor | 3 | 0.667 | 1.000 | C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain) DAGK_acc (PF00609, IPR000756, SM00045): Diacylglycerol kinase accessory domain DAGK_cat (PF00781, IPR001206, SM00046): Diacylglycerol kinase catalytic domain Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_4 (PF13637): Ankyrin repeats (many copies) |
73 |
DNAJA1 | interactor | 18 | 0.516 | 29.958 | DnaJ (PF00226, IPR001623, SM00271): DnaJ domain DnaJ_C (PF01556, IPR002939): DnaJ C terminal domain |
74 |
DNAJA2 | interactor | 15 | 0.581 | 9.412 | DnaJ (PF00226, IPR001623, SM00271): DnaJ domain DnaJ_C (PF01556, IPR002939): DnaJ C terminal domain |
75 |
DNAJA3 | suppressor | 11 | 0.491 | 18.828 | DnaJ (PF00226, IPR001623, SM00271): DnaJ domain DnaJ_C (PF01556, IPR002939): DnaJ C terminal domain |
76 |
DVL2 | interactor | 10 | 0.444 | 14.144 | DEP (PF00610, IPR000591, SM00049): Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Dishevelled (PF02377, IPR003351): Dishevelled specific domain PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) DIX (PF00778, IPR001158, SM00021): DIX domain Dsh_C (PF12316, IPR024580): Segment polarity protein dishevelled (Dsh) C terminal |
77 |
E2F1 | oncoprotein | 17 | 0.471 | 21.297 | Cellsynth_D (PF03500, IPR022798): Cellulose synthase subunit D E2F_TDP (PF02319, IPR003316): E2F/DP family winged-helix DNA-binding domain E2F_CC-MB (PF16421, IPR032198): E2F transcription factor CC-MB domain |
78 |
EEF1B2 | interactor | 13 | 0.424 | 13.400 | EF1_GNE (PF00736, IPR014038, SM00888): EF-1 guanine nucleotide exchange domain EF-1_beta_acid (PF10587, IPR018940): Eukaryotic elongation factor 1 beta central acidic region GST_C_6 (PF17171): Glutathione S-transferase, C-terminal domain |
79 |
EGLN1 | oncoprotein | 13 | 0.258 | 41.289 | zf-MYND (PF01753, IPR002893): MYND finger 2OG-FeII_Oxy_3 (PF13640, IPR005123): 2OG-Fe(II) oxygenase superfamily |
80 |
EIF5A | interactor | 7 | 0.667 | 2.001 | EFP_N (PF08207, IPR013185): Elongation factor P (EF-P) KOW-like domain eIF-5a (PF01287, IPR020189): Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold |
81 |
EIF5A2 | interactor | 4 | 0.833 | 0.500 | EFP_N (PF08207, IPR013185): Elongation factor P (EF-P) KOW-like domain eIF-5a (PF01287, IPR020189): Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold |
82 |
ELAVL1 | oncoprotein | 53 | 0.186 | 690.671 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
83 |
EP300 | oncoprotein | 35 | 0.308 | 169.143 | Creb_binding (PF09030, IPR014744): Creb binding DUF902 (PF06001, IPR010303): Domain of Unknown Function (DUF902) Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region KIX (PF02172, IPR003101): KIX domain RR_TM4-6 (PF06459, IPR009460): Ryanodine Receptor TM 4-6 TPX2 (PF06886, IPR027329): Targeting protein for Xklp2 (TPX2) zf-TAZ (PF02135, IPR000197, SM00551): TAZ zinc finger HAT_KAT11 (PF08214, IPR013178): Histone acetylation protein Bromodomain (PF00439, IPR001487, SM00297): Bromodomain ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type |
84 |
EPAS1 | suppressor | 17 | 0.350 | 31.332 | Corona_I (PF03187, IPR004876): Corona nucleocapsid I protein HIF-1a_CTAD (PF08778, IPR014887): HIF-1 alpha C terminal transactivation domain HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain PAS (PF00989, IPR013767, SM00091): PAS fold HIF-1 (PF11413, IPR021537): Hypoxia-inducible factor-1 PAS_11 (PF14598): PAS domain |
85 |
EPHA4 | interactor | 3 | 0.667 | 0.400 | fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain Ephrin_rec_like (PF07699, IPR011641): Putative ephrin-receptor like Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SAM_2 (PF07647, IPR011510): SAM domain (Sterile alpha motif) DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369) Ephrin_lbd (PF01404, IPR001090, SM00615): Ephrin receptor ligand binding domain SusE (PF14292, IPR025970): SusE outer membrane protein EphA2_TM (PF14575, IPR027936): Ephrin type-A receptor 2 transmembrane domain |
86 |
EPOR | oncoprotein | 7 | 0.714 | 2.919 | EpoR_lig-bind (PF09067, IPR015152): Erythropoietin receptor, ligand binding fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain |
87 |
EXOSC8 | interactor | 5 | 0.833 | 0.074 | RNase_PH (PF01138, IPR001247): 3' exoribonuclease family, domain 1 RNase_PH_C (PF03725, IPR015847): 3' exoribonuclease family, domain 2 |
88 |
FASTKD3 | interactor | 2 | 1.000 | 0 | FAST_1 (PF06743, IPR010622): FAST kinase-like protein, subdomain 1 FAST_2 (PF08368, IPR013579): FAST kinase-like protein, subdomain 2 NUC205 (PF08168, IPR012584): NUC205 domain RAP (PF08373, IPR013584, SM00952): RAP domain |
89 |
FKBP8 | protein found in more fusions | 10 | 0.472 | 10.669 | FKBP_C (PF00254, IPR001179): FKBP-type peptidyl-prolyl cis-trans isomerase TPR_9 (PF13371, IPR011990): Tetratricopeptide repeat TPR_16 (PF13432): Tetratricopeptide repeat Fis1_TPR_C (PF14853, IPR028061): Fis1 C-terminal tetratricopeptide repeat |
90 |
FLNA | suppressor | 17 | 0.368 | 46.294 | CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain Filamin (PF00630, IPR017868): Filamin/ABP280 repeat |
91 |
FN1 | oncoprotein | 97 | 0.175 | 1916.994 | fn1 (PF00039, IPR000083, SM00058): Fibronectin type I domain fn2 (PF00040, IPR000562, SM00059): Fibronectin type II domain fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369) |
92 |
FSCN1 | oncoprotein | 7 | 0.619 | 3.387 | Fascin (PF06268, IPR022768): Fascin domain |
93 |
FZR1 | suppressor | 8 | 0.393 | 11.165 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain |
94 |
GLI1 | oncoprotein | 9 | 0.528 | 6.682 | zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain FOXP-CC (PF16159, IPR032354): FOXP coiled-coil domain |
95 |
GOLGA4 | interactor | 4 | 0.667 | 0.917 | ACCA (PF03255, IPR001095): Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16) DivIC (PF04977, IPR007060): Septum formation initiator DUF106 (PF01956, IPR002809): Integral membrane protein DUF106 DUF16 (PF01519, IPR002862): Protein of unknown function DUF16 DUF641 (PF04859, IPR006943): Plant protein of unknown function (DUF641) DUF724 (PF05266, IPR007930): Protein of unknown function (DUF724) Fez1 (PF06818): Fez1 FlaC_arch (PF05377, IPR008039): Flagella accessory protein C (FlaC) GRIP (PF01465, IPR000237, SM00755): GRIP domain Mnd1 (PF03962, IPR005647): Mnd1 family Pox_A_type_inc (PF04508, IPR007596): Viral A-type inclusion protein repeat Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein SlyX (PF04102, IPR007236): SlyX Atg14 (PF10186, IPR018791): Vacuolar sorting 38 and autophagy-related subunit 14 XhlA (PF10779, IPR019715): Haemolysin XhlA YlqD (PF11068, IPR021297): YlqD protein ADIP (PF11559, IPR021622): Afadin- and alpha -actinin-Binding DUF4407 (PF14362, IPR025519): Domain of unknown function (DUF4407) CCDC-167 (PF15188, IPR028194): Coiled-coil domain-containing protein 167 PRKG1_interact (PF15898, IPR031775): cGMP-dependent protein kinase interacting domain RecQ_Zn_bind (PF16124, IPR032284): RecQ zinc-binding PKcGMP_CC (PF16808, IPR031831): Coiled-coil N-terminus of cGMP-dependent protein kinase TetR_C_13 (PF16925, IPR011075): Bacterial transcriptional repressor C-terminal |
96 |
GPLD1 | interactor | 3 | 1.000 | 0 | FG-GAP (PF01839, IPR013517): FG-GAP repeat Zn_dep_PLPC (PF00882, IPR029002, SM00770): Zinc dependent phospholipase C |
97 |
GRN | oncoprotein | 3 | 0.667 | 0.500 | Granulin (PF00396, IPR000118, SM00277): Granulin Lustrin_cystein (PF14625, IPR028150): Lustrin, cysteine-rich repeated domain |
98 |
GRWD1 | interactor | 4 | 1.000 | 0 | Voldacs (PF03517): Regulator of volume decrease after cellular swelling WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat CAF1C_H4-bd (PF12265, IPR022052): Histone-binding protein RBBP4 or subunit C of CAF1 complex |
99 |
HAS1 | interactor | 1 | 0 | 0 | Glycos_transf_2 (PF00535, IPR001173): Glycosyl transferase family 2 Glyco_tranf_2_3 (PF13641): Glycosyltransferase like family 2 |
100 |
HDAC1 | suppressor | 43 | 0.266 | 314.742 | FSAP_sig_propep (PF03032, IPR004275): Frog skin active peptide family signal and propeptide Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain |
101 |
HDAC2 | oncoprotein | 26 | 0.353 | 77.704 | Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain NARP1 (PF12569, IPR021183): NMDA receptor-regulated protein 1 |
102 |
HDAC3 | oncoprotein | 28 | 0.328 | 73.691 | Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain |
103 |
HIF1A | suppressor | 43 | 0.216 | 469.895 | Dicty_REP (PF05086, IPR007778): Dictyostelium (Slime Mold) REP protein HIF-1a_CTAD (PF08778, IPR014887): HIF-1 alpha C terminal transactivation domain HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain PAS (PF00989, IPR013767, SM00091): PAS fold PAS_3 (PF08447, IPR013655): PAS fold HIF-1 (PF11413, IPR021537): Hypoxia-inducible factor-1 |
104 |
HIF1AN | protein found in more fusions | 7 | 0.667 | 0.860 | Cupin_8 (PF13621): Cupin-like domain |
105 |
HIF3A | interactor | 2 | 1.000 | 0 | HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain PAS (PF00989, IPR013767, SM00091): PAS fold Spo0M (PF07070, IPR009776): SpoOM protein HIF-1 (PF11413, IPR021537): Hypoxia-inducible factor-1 PAS_11 (PF14598): PAS domain |
106 |
HIST1H1C | oncoprotein | 9 | 0.694 | 2.651 | Amelin (PF05111, IPR007798, SM00817): Ameloblastin precursor (Amelin) Linker_histone (PF00538, IPR005818, SM00526): linker histone H1 and H5 family DUF4349 (PF14257, IPR025645): Domain of unknown function (DUF4349) |
107 |
HIST1H2BC | interactor | 2 | 1.000 | 0 | Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4 |
108 |
HIST1H2BL | interactor | 3 | 1.000 | 0 | Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4 |
109 |
HIST4H4 | interactor | 11 | 0.364 | 14.455 | CENP-T_C (PF15511): Centromere kinetochore component CENP-T histone fold |
110 |
HNRNPA1 | interactor | 57 | 0.349 | 404.348 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HnRNPA1 (PF11627, IPR021662): Nuclear factor hnRNPA1 |
111 |
HNRNPA2B1 | oncoprotein | 31 | 0.473 | 102.650 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
112 |
HNRNPA3 | oncoprotein | 23 | 0.783 | 6.272 | IATP (PF04568, IPR007648): Mitochondrial ATPase inhibitor, IATP RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 |
113 |
HNRNPAB | interactor | 17 | 0.794 | 3.131 | CBFNT (PF08143, IPR012956): CBFNT (NUC161) domain GRP (PF07172, IPR010800): Glycine rich protein family NID (PF07292, IPR009909): Nmi/IFP 35 domain (NID) RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2462 (PF09495, IPR019034): Protein of unknown function (DUF2462) |
114 |
HNRNPC | protein found in more fusions | 26 | 0.453 | 60.593 | APG6 (PF04111, IPR007243): Autophagy protein Apg6 RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SURF2 (PF05477, IPR008833): Surfeit locus protein 2 (SURF2) |
115 |
HNRNPD | oncoprotein | 38 | 0.416 | 149.871 | CBFNT (PF08143, IPR012956): CBFNT (NUC161) domain NID (PF07292, IPR009909): Nmi/IFP 35 domain (NID) RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Keratin_2_head (PF16208, IPR032444): Keratin type II head |
116 |
HNRNPDL | interactor | 24 | 0.707 | 10.875 | CBFNT (PF08143, IPR012956): CBFNT (NUC161) domain RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
117 |
HNRNPH1 | oncoprotein | 33 | 0.564 | 51.694 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RNPHF (PF08080, IPR012996): RNPHF zinc finger |
118 |
HNRNPH2 | interactor | 23 | 0.645 | 27.500 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RNPHF (PF08080, IPR012996): RNPHF zinc finger |
119 |
HNRNPK | oncoprotein | 38 | 0.470 | 100.618 | ROKNT (PF08067, IPR012987): ROKNT (NUC014) domain KH_1 (PF00013, IPR004088, SM00322): KH domain |
120 |
HNRNPL | protein found in more fusions | 24 | 0.656 | 18.087 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Dscam_C (PF12355, IPR021012): Down syndrome cell adhesion molecule C terminal RRM_5 (PF13893): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
121 |
HNRNPLL | protein found in more fusions | 5 | 0.500 | 1.400 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 (PF11608, IPR024582): Limkain b1 RRM_5 (PF13893): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
122 |
HNRNPM | interactor | 36 | 0.535 | 76.143 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HnRNP_M (PF11532, IPR024666): Heterogeneous nuclear ribonucleoprotein M Collagen_mid (PF15984, IPR031929): Bacterial collagen, middle region |
123 |
HNRNPR | interactor | 31 | 0.518 | 54.363 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 (PF11608, IPR024582): Limkain b1 |
124 |
HNRNPU | interactor | 65 | 0.377 | 433.793 | CDC45 (PF02724, IPR003874): CDC45-like protein Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein SAP (PF02037, IPR003034, SM00513): SAP domain SPRY (PF00622, IPR003877, SM00449): SPRY domain AAA_33 (PF13671): AAA domain WRNPLPNID (PF15017): Putative WW-binding domain and destruction box |
125 |
HSP90AA1 | oncoprotein | 57 | 0.264 | 601.792 | HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HSP90 (PF00183, IPR001404): Hsp90 protein |
126 |
HSPA1A | interactor | 25 | 0.423 | 67.141 | HSP70 (PF00012, IPR013126): Hsp70 protein |
127 |
HSPA4 | interactor | 34 | 0.330 | 133.261 | Herpes_ICP4_N (PF03584, IPR005206): Herpesvirus ICP4-like protein N-terminal region HSP70 (PF00012, IPR013126): Hsp70 protein TP53IP5 (PF15331, IPR029290): Cellular tumour antigen p53-inducible 5 |
128 |
HSPA5 | oncoprotein | 50 | 0.334 | 364.687 | HSP70 (PF00012, IPR013126): Hsp70 protein |
129 |
HSPA8 | oncoprotein | 41 | 0.311 | 248.308 | HSP70 (PF00012, IPR013126): Hsp70 protein |
130 |
IARS | interactor | 13 | 0.385 | 21.437 | Anticodon_1 (PF08264, IPR013155): Anticodon-binding domain of tRNA tRNA-synt_1 (PF00133, IPR002300): tRNA synthetases class I (I, L, M and V) |
131 |
ID1 | interactor | 3 | 0.667 | 0.667 | HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain |
132 |
ID2 | oncoprotein | 9 | 0.464 | 6.168 | HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain |
133 |
ID3 | oncoprotein | 4 | 0.667 | 0.250 | HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain |
134 |
ILF3 | oncoprotein | 46 | 0.429 | 218.330 | dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif DZF (PF07528, IPR006561, SM00572): DZF domain |
135 |
IMPDH2 | protein found in more fusions | 10 | 0.472 | 5.367 | IMPDH (PF00478, IPR001093): IMP dehydrogenase / GMP reductase domain |
136 |
IREB2 | interactor | 2 | 1.000 | 0 | Aconitase (PF00330, IPR001030): Aconitase family (aconitate hydratase) Aconitase_C (PF00694, IPR000573): Aconitase C-terminal domain |
137 |
IVNS1ABP | protein found in more fusions | 18 | 0.507 | 11.228 | BACK (PF07707, IPR011705, SM00875): BTB And C-terminal Kelch BTB (PF00651, IPR013069, SM00225): BTB/POZ domain Kelch_1 (PF01344, IPR006652, SM00612): Kelch motif |
138 |
JADE1 | interactor | 2 | 1.000 | 0 | C1_2 (PF03107, IPR004146): C1 domain Glyco_hydro_57 (PF03065, IPR004300): Glycosyl hydrolase family 57 EPL1 (PF10513, IPR019542): Enhancer of polycomb-like eIF-5_eIF-2B (PF01873, IPR002735, SM00653): Domain found in IF2B/IF5 PHD_2 (PF13831): PHD-finger zf-HC5HC2H_2 (PF13832): PHD-zinc-finger like domain |
139 |
JAK2 | oncoprotein | 10 | 0.361 | 16.033 | FERM_M (PF00373, IPR019748): FERM central domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain |
140 |
JMJD1C | interactor | 2 | 1.000 | 0 | ArfGap (PF01412, IPR001164, SM00105): Putative GTPase activating protein for Arf JmjC (PF02373, IPR003347, SM00558): JmjC domain, hydroxylase TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit zf-C5HC2 (PF02928, IPR004198): C5HC2 zinc finger RbpA (PF13397, IPR025182): RNA polymerase-binding protein |
141 |
KAT2B | protein found in more fusions | 24 | 0.368 | 67.732 | Acetyltransf_1 (PF00583, IPR000182): Acetyltransferase (GNAT) family PCAF_N (PF06466, IPR009464): PCAF (P300/CBP-associated factor) N-terminal domain Bromodomain (PF00439, IPR001487, SM00297): Bromodomain |
142 |
KAT5 | oncoprotein | 22 | 0.333 | 76.864 | MOZ_SAS (PF01853, IPR002717): MOZ/SAS family Tudor-knot (PF11717, IPR025995): RNA binding activity-knot of a chromodomain |
143 |
KIF2C | interactor | 6 | 0.600 | 0.413 | Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family Kinesin (PF00225, IPR001752, SM00129): Kinesin motor domain |
144 |
KIF3A | interactor | 4 | 0.833 | 0.667 | Bacillus_HBL (PF05791, IPR008414): Bacillus haemolytic enterotoxin (HBL) DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664) Vfa1 (PF08432, IPR013640): AAA-ATPase Vps4-associated protein 1 DUF755 (PF05501, IPR008474): Domain of unknown function (DUF755) Fez1 (PF06818): Fez1 Kinesin (PF00225, IPR001752, SM00129): Kinesin motor domain DUF4200 (PF13863, IPR025252): Domain of unknown function (DUF4200) |
145 |
KIF3B | interactor | 4 | 0.833 | 0.667 | DUF948 (PF06103, IPR009293): Bacterial protein of unknown function (DUF948) Kinesin (PF00225, IPR001752, SM00129): Kinesin motor domain WRNPLPNID (PF15017): Putative WW-binding domain and destruction box Kinesin_assoc (PF16183, IPR032405): Kinesin-associated HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1 |
146 |
KIFAP3 | interactor | 6 | 0.400 | 9.000 | KAP (PF05804): Kinesin-associated protein (KAP) |
147 |
KIRREL2 | interactor | 2 | 1.000 | 0 | C2-set_2 (PF08205, IPR013162): CD80-like C2-set immunoglobulin domain I-set (PF07679, IPR013098): Immunoglobulin I-set domain ig (PF00047, IPR013151, SM00409): Immunoglobulin domain SepZ (PF06066, IPR009275): SepZ Ig_3 (PF13927): Immunoglobulin domain |
148 |
KLF4 | oncoprotein | 11 | 0.436 | 10.647 | zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain |
149 |
KNG1 | interactor | 1 | 0 | 0 | Bradykinin (PF06753, IPR009608): Bradykinin Chorion_2 (PF03964, IPR005649): Chorion family 2 Cystatin (PF00031, IPR000010, SM00043): Cystatin domain |
150 |
KNTC1 | interactor | 3 | 0.667 | 1.000 | DUF2240 (PF09999, IPR018716): Uncharacterized protein conserved in archaea (DUF2240) MRP-S22 (PF10245, IPR019374): Mitochondrial 28S ribosomal protein S22 Rod_C (PF10493, IPR019527): Rough deal protein C-terminal region |
151 |
LANCL1 | interactor | 2 | 1.000 | 0 | LANC_like (PF05147, IPR007822): Lanthionine synthetase C-like protein |
152 |
LIMD1 | oncoprotein | 7 | 0.533 | 5.667 | LIM (PF00412, IPR001781, SM00132): LIM domain |
153 |
LPP | oncoprotein | 6 | 0.667 | 2.944 | LIM (PF00412, IPR001781, SM00132): LIM domain zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger) |
154 |
LTV1 | interactor | 7 | 0.619 | 1.133 | DUF1874 (PF08960, IPR015055): Domain of unknown function (DUF1874) LTV (PF04180, IPR007307): Low temperature viability protein |
155 |
MCC | oncoprotein | 7 | 0.333 | 12.167 | ERM (PF00769, IPR011259): Ezrin/radixin/moesin family IFP_35_N (PF07334, IPR009938): Interferon-induced 35 kDa protein (IFP 35) N-terminus K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain Mod_r (PF07200, IPR009851): Modifier of rudimentary (Mod(r)) protein Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein MCC-bdg_PDZ (PF10506, IPR019536): PDZ domain of MCC-2 bdg protein for Usher syndrome TMF_DNA_bd (PF12329, IPR022092): TATA element modulatory factor 1 DNA binding EF-hand_7 (PF13499, IPR011992): EF-hand domain pair FAM76 (PF16046, IPR032017): FAM76 protein |
156 |
MCM7 | protein found in more fusions | 17 | 0.400 | 22.288 | MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family MCM_N (PF14551, IPR027925): MCM N-terminal domain MCM_OB (PF17207): MCM OB domain |
157 |
MDFI | interactor | 10 | 0.250 | 22.341 | MDFI (PF15316, IPR026134): MyoD family inhibitor |
158 |
MIF | oncoprotein | 12 | 0.491 | 14.399 | MIF (PF01187, IPR001398): Macrophage migration inhibitory factor (MIF) |
159 |
MKNK2 | interactor | 7 | 0.429 | 7.137 | ABC_trans_aux (PF03886, IPR005586): ABC-type transport auxiliary lipoprotein component Pkinase (PF00069, IPR000719): Protein kinase domain |
160 |
MOB4 | interactor | 11 | 0.564 | 20.000 | Mob1_phocein (PF03637, IPR005301): Mob1/phocein family |
161 |
MSH4 | interactor | 2 | 1.000 | 0 | MutS_II (PF05188, IPR007860): MutS domain II MutS_V (PF00488, IPR000432, SM00534): MutS domain V MutS_III (PF05192, IPR007696, SM00533): MutS domain III |
162 |
MYBBP1A | oncoprotein | 22 | 0.450 | 51.804 | DNA_pol_phi (PF04931, IPR007015): DNA polymerase phi Pol_alpha_B_N (PF08418, IPR013627): DNA polymerase alpha subunit B N-terminal |
163 |
MYC | oncoprotein | 65 | 0.192 | 825.417 | HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain Myc-LZ (PF02344, IPR003327): Myc leucine zipper domain Myc_N (PF01056, IPR012682): Myc amino-terminal region |
164 |
MYL12A | interactor | 4 | 0.667 | 0.393 | EF-hand_11 (PF08976, IPR015070): EF-hand domain DUF2267 (PF10025, IPR018727): Uncharacterized conserved protein (DUF2267) EF-hand_7 (PF13499, IPR011992): EF-hand domain pair |
165 |
NCL | protein found in more fusions | 40 | 0.409 | 145.777 | DUF1754 (PF08555, IPR013865): Eukaryotic family of unknown function (DUF1754) Myc_N (PF01056, IPR012682): Myc amino-terminal region RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) YL1 (PF05764, IPR008895): YL1 nuclear protein Limkain-b1 (PF11608, IPR024582): Limkain b1 |
166 |
NEDD8 | interactor | 47 | 0.379 | 189.753 | ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family |
167 |
NKRF | interactor | 5 | 0.900 | 0.043 | dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif G-patch (PF01585, IPR000467, SM00443): G-patch domain R3H (PF01424, IPR001374, SM00393): R3H domain XTBD (PF11952, IPR021859): XRN-Two Binding Domain, XTBD |
168 |
NOB1 | interactor | 3 | 0.667 | 0.154 | NOB1_Zn_bind (PF08772, IPR014881): Nin one binding (NOB1) Zn-ribbon like WRNPLPNID (PF15017): Putative WW-binding domain and destruction box PIN_6 (PF17146): PIN domain of ribonuclease |
169 |
NR4A1 | suppressor | 11 | 0.527 | 8.521 | zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor |
170 |
OSR1 | interactor | 2 | 1.000 | 0 | zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain |
171 |
P3H1 | interactor | 5 | 0.500 | 4.067 | TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat YfiO (PF13525): Outer membrane lipoprotein 2OG-FeII_Oxy_3 (PF13640, IPR005123): 2OG-Fe(II) oxygenase superfamily MCM_N (PF14551, IPR027925): MCM N-terminal domain Fis1_TPR_C (PF14853, IPR028061): Fis1 C-terminal tetratricopeptide repeat |
172 |
PAPSS2 | interactor | 3 | 0.667 | 0.250 | APS_kinase (PF01583, IPR002891): Adenylylsulphate kinase ATP-sulfurylase (PF01747, IPR024951): ATP-sulfurylase DUF258 (PF03193, IPR004881): Protein of unknown function, DUF258 YscJ_FliF (PF01514, IPR006182): Secretory protein of YscJ/FliF family PUA_2 (PF14306, IPR025980): PUA-like domain |
173 |
PARD3 | interactor | 7 | 0.429 | 8.111 | PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) DUF3534 (PF12053, IPR021922): Domain of unknown function (DUF3534) PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term |
174 |
PARD6A | interactor | 6 | 0.600 | 4.900 | PB1 (PF00564, IPR000270, SM00666): PB1 domain PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) |
175 |
PARK7 | suppressor | 11 | 0.644 | 6.598 | DJ-1_PfpI (PF01965, IPR002818): DJ-1/PfpI family |
176 |
PARP1 | suppressor | 27 | 0.357 | 72.490 | BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain PADR1 (PF08063, IPR012982): PADR1 (NUC008) domain PARP (PF00644, IPR012317): Poly(ADP-ribose) polymerase catalytic domain PARP_reg (PF02877, IPR004102): Poly(ADP-ribose) polymerase, regulatory domain WGR (PF05406, IPR008893, SM00773): WGR domain zf-PARP (PF00645, IPR001510): Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region |
177 |
PCGF2 | suppressor | 4 | 0.667 | 0.143 | zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger) RAWUL (PF16207, IPR032443): RAWUL domain RING finger- and WD40-associated ubiquitin-like |
178 |
PCMT1 | interactor | 10 | 0.489 | 8.315 | PCMT (PF01135, IPR000682): Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) |
179 |
PDCD5 | suppressor | 4 | 0.667 | 0.255 | dsDNA_bind (PF01984, IPR002836): Double-stranded DNA-binding domain EF-1_beta_acid (PF10587, IPR018940): Eukaryotic elongation factor 1 beta central acidic region |
180 |
PFAS | interactor | 2 | 1.000 | 0 | AIRS_C (PF02769, IPR010918): AIR synthase related protein, C-terminal domain GATase_5 (PF13507): CobB/CobQ-like glutamine amidotransferase domain |
181 |
PIAS4 | interactor | 13 | 0.372 | 31.225 | CENP-B_dimeris (PF09026, IPR015115): Centromere protein B dimerisation domain SAP (PF02037, IPR003034, SM00513): SAP domain zf-MIZ (PF02891, IPR004181): MIZ/SP-RING zinc finger PINIT (PF14324, IPR023321): PINIT domain |
182 |
PIN1 | suppressor | 23 | 0.364 | 82.703 | Rotamase (PF00639, IPR000297): PPIC-type PPIASE domain WW (PF00397, IPR001202, SM00456): WW domain |
183 |
PKD1L3 | interactor | 1 | 0 | 0 | GPS (PF01825, IPR000203, SM00303): GPCR proteolysis site, GPS, motif PKD_channel (PF08016, IPR013122): Polycystin cation channel PLAT (PF01477, IPR001024, SM00308): PLAT/LH2 domain Lectin_C (PF00059, IPR001304, SM00034): Lectin C-type domain |
184 |
PLD1 | oncoprotein | 3 | 1.000 | 0 | PH (PF00169, IPR001849, SM00233): PH domain PLDc (PF00614, IPR001736, SM00155): Phospholipase D Active site motif PX (PF00787, IPR001683, SM00312): PX domain PLDc_2 (PF13091, IPR025202): PLD-like domain |
185 |
PLD2 | interactor | 5 | 0.500 | 2.872 | PH (PF00169, IPR001849, SM00233): PH domain PLDc (PF00614, IPR001736, SM00155): Phospholipase D Active site motif PX (PF00787, IPR001683, SM00312): PX domain PLDc_2 (PF13091, IPR025202): PLD-like domain |
186 |
PLOD2 | protein found in more fusions | 7 | 0.533 | 3.773 | 2OG-FeII_Oxy (PF03171, IPR005123): 2OG-Fe(II) oxygenase superfamily Anp1 (PF03452, IPR005109): Anp1 Glycos_transf_2 (PF00535, IPR001173): Glycosyl transferase family 2 |
187 |
PLOD3 | protein found in more fusions | 8 | 0.381 | 6.258 | 2OG-FeII_Oxy (PF03171, IPR005123): 2OG-Fe(II) oxygenase superfamily Anp1 (PF03452, IPR005109): Anp1 |
188 |
POLR2A | protein found in more fusions | 27 | 0.295 | 126.536 | RNA_pol_Rpb1_1 (PF04997, IPR007080): RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 (PF00623, IPR000722): RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 (PF04983, IPR007066): RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 (PF05000, IPR007083): RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_5 (PF04998, IPR007081): RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_R (PF05001, IPR000684): RNA polymerase Rpb1 C-terminal repeat |
189 |
POLR2G | interactor | 4 | 1.000 | 0 | SHS2_Rpb7-N (PF03876, IPR005576): SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 (PF00575, IPR003029, SM00316): S1 RNA binding domain |
190 |
PPIB | interactor | 4 | 0.833 | 0.500 | Pro_isomerase (PF00160, IPR002130): Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD |
191 |
PPM1B | interactor | 4 | 0.500 | 2.667 | PP2C (PF00481, IPR001932): Protein phosphatase 2C PP2C_C (PF07830, IPR012911, SM00332): Protein serine/threonine phosphatase 2C, C-terminal domain |
192 |
PRDX1 | oncoprotein | 14 | 0.526 | 9.633 | AhpC-TSA (PF00578, IPR000866): AhpC/TSA family 1-cysPrx_C (PF10417, IPR019479): C-terminal domain of 1-Cys peroxiredoxin |
193 |
PRKCD | oncoprotein | 12 | 0.527 | 10.356 | Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain) |
194 |
PRKCH | protein found in more fusions | 4 | 1.000 | 0 | C2 (PF00168, IPR000008, SM00239): C2 domain Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain) |
195 |
PRKCI | interactor | 8 | 0.464 | 10.151 | PB1 (PF00564, IPR000270, SM00666): PB1 domain Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain) |
196 |
PRKCZ | interactor | 12 | 0.327 | 27.908 | PB1 (PF00564, IPR000270, SM00666): PB1 domain Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain) |
197 |
PRMT1 | interactor | 19 | 0.490 | 25.197 | Methyltransf_25 (PF13649): Methyltransferase domain |
198 |
PRMT3 | interactor | 7 | 0.524 | 3.054 | PrmA (PF06325, IPR010456): Ribosomal protein L11 methyltransferase (PrmA) zf-C2H2_2 (PF12756, IPR015880): C2H2 type zinc-finger (2 copies) |
199 |
PRMT8 | interactor | 6 | 1.000 | 0 | PrmA (PF06325, IPR010456): Ribosomal protein L11 methyltransferase (PrmA) |
200 |
PSMB1 | interactor | 15 | 0.438 | 27.853 | Proteasome (PF00227, IPR001353): Proteasome subunit |
201 |
PSMB3 | protein found in more fusions | 9 | 0.714 | 2.416 | Proteasome (PF00227, IPR001353): Proteasome subunit |
202 |
PSMC3 | interactor | 14 | 0.436 | 22.918 | AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA) DUF3713 (PF12506, IPR022186): Protein of unknown function (DUF3713) JIP_LZII (PF16471, IPR032486): JNK-interacting protein leucine zipper II |
203 |
PSMD13 | interactor | 8 | 0.643 | 4.169 | Mitovir_RNA_pol (PF05919, IPR008686): Mitovirus RNA-dependent RNA polymerase PCI (PF01399, IPR000717, SM00088): PCI domain |
204 |
PTPN14 | oncoprotein | 4 | 0.667 | 0.157 | FERM_C (PF09380, IPR018980): FERM C-terminal PH-like domain FERM_M (PF00373, IPR019748): FERM central domain FERM_N (PF09379, IPR018979): FERM N-terminal domain Y_phosphatase (PF00102, IPR000242, SM00194): Protein-tyrosine phosphatase |
205 |
RAB1B | oncoprotein | 3 | 0.667 | 0.333 | Ras (PF00071, IPR001806, SM00173): Ras family |
206 |
RACK1 | oncoprotein | 33 | 0.440 | 123.804 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain |
207 |
RALYL | protein found in more fusions | 3 | 1.000 | 0 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TFIIIC_sub6 (PF10419, IPR019481): TFIIIC subunit CENP-Q (PF13094, IPR025212): CENP-Q, a CENPA-CAD centromere complex subunit |
208 |
RASGRP1 | oncoprotein | 3 | 0.667 | 1.000 | bZIP_1 (PF00170, IPR004827): bZIP transcription factor FlaC_arch (PF05377, IPR008039): Flagella accessory protein C (FlaC) RasGEF (PF00617, IPR001895, SM00147): RasGEF domain C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain) EF-hand_1 (PF00036, IPR002048, SM00054): EF hand RasGEF_N (PF00618, IPR000651, SM00229): RasGEF N-terminal motif EF-hand_7 (PF13499, IPR011992): EF-hand domain pair |
209 |
RB1CC1 | oncoprotein | 5 | 0.600 | 2.139 | Arc_PepC_II (PF06847, IPR009655): Archaeal Peptidase A24 C-terminus Type II DHC (PF09626, IPR018588): Dihaem cytochrome c DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972) FlaC_arch (PF05377, IPR008039): Flagella accessory protein C (FlaC) ATG11 (PF10377, IPR019460): Autophagy-related protein 11 DUF4407 (PF14362, IPR025519): Domain of unknown function (DUF4407) Jag_N (PF14804, IPR032782): Jag N-terminus NPBW (PF15180, IPR013297): Neuropeptides B and W HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1 BST2 (PF16716, IPR024886): Bone marrow stromal antigen 2 Goodbye (PF17109, IPR031350): fungal STAND N-terminal Goodbye domain |
210 |
RBBP4 | oncoprotein | 18 | 0.379 | 43.223 | eIF2A (PF08662, IPR013979): Eukaryotic translation initiation factor eIF2A WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Capsid_NCLDV (PF04451, IPR007542): Large eukaryotic DNA virus major capsid protein CAF1C_H4-bd (PF12265, IPR022052): Histone-binding protein RBBP4 or subunit C of CAF1 complex |
211 |
RBBP7 | oncoprotein | 11 | 0.564 | 13.088 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Capsid_NCLDV (PF04451, IPR007542): Large eukaryotic DNA virus major capsid protein CAF1C_H4-bd (PF12265, IPR022052): Histone-binding protein RBBP4 or subunit C of CAF1 complex |
212 |
RBPMS | protein found in more fusions | 8 | 0.286 | 11.056 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
213 |
RBPMS2 | interactor | 1 | 0 | 0 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
214 |
RBX1 | oncoprotein | 23 | 0.416 | 56.997 | zf-rbx1 (PF12678, IPR024766): RING-H2 zinc finger domain |
215 |
RHOBTB3 | protein found in more fusions | 8 | 0.476 | 7.721 | BTB (PF00651, IPR013069, SM00225): BTB/POZ domain Ras (PF00071, IPR001806, SM00173): Ras family |
216 |
RHOC | oncoprotein | 2 | 1.000 | 0 | Ras (PF00071, IPR001806, SM00173): Ras family |
217 |
RIT1 | interactor | 1 | 0 | 0 | Ras (PF00071, IPR001806, SM00173): Ras family |
218 |
RNF7 | oncoprotein | 12 | 0.473 | 13.037 | zf-rbx1 (PF12678, IPR024766): RING-H2 zinc finger domain Prok-RING_1 (PF14446): Prokaryotic RING finger family 1 |
219 |
RPA3 | interactor | 42 | 0.288 | 179.989 | Rep_fac-A_3 (PF08661, IPR013970): Replication factor A protein 3 |
220 |
RPL10A | interactor | 34 | 0.747 | 27.010 | Ribosomal_L1 (PF00687, IPR028364): Ribosomal protein L1p/L10e family |
221 |
RPL11 | suppressor | 38 | 0.697 | 31.456 | Ribosomal_L5 (PF00281, IPR002132): Ribosomal protein L5 Ribosomal_L5_C (PF00673, IPR002132): ribosomal L5P family C-terminus |
222 |
RPL12 | interactor | 38 | 0.700 | 54.181 | Ribosomal_L11 (PF00298, IPR020783): Ribosomal protein L11, RNA binding domain Ribosomal_L11_N (PF03946, IPR020784): Ribosomal protein L11, N-terminal domain |
223 |
RPL14 | interactor | 34 | 0.761 | 19.959 | KOW (PF00467, IPR005824, SM00739): KOW motif Ribosomal_L14e (PF01929, IPR002784): Ribosomal protein L14 UPF0688 (PF15772, IPR031530): UPF0688 family |
224 |
RPL18A | interactor | 30 | 0.814 | 10.286 | Ribosomal_L18A (PF01775, IPR023573): Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A |
225 |
RPL21 | interactor | 34 | 0.777 | 27.810 | Ribosomal_L21e (PF01157, IPR001147): Ribosomal protein L21e |
226 |
RPL30 | interactor | 30 | 0.807 | 20.479 | NCBP3 (PF10309, IPR019416): Nuclear cap-binding protein subunit 3 |
227 |
RPL5 | oncoprotein | 44 | 0.574 | 125.929 | Ribosomal_L18_c (PF14204, IPR025607): Ribosomal L18 C-terminal region Ribosomal_L5e (PF17144): Ribosomal large subunit proteins 60S L5, and 50S L18 |
228 |
RPL7A | interactor | 34 | 0.677 | 68.738 | Ribosomal_L7Ae (PF01248, IPR004038): Ribosomal protein L7Ae/L30e/S12e/Gadd45 family |
229 |
RPLP0 | interactor | 43 | 0.591 | 78.134 | Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein Ribosomal_L10 (PF00466, IPR001790): Ribosomal protein L10 |
230 |
RPS11 | interactor | 34 | 0.724 | 23.780 | Ribosomal_S17 (PF00366, IPR000266): Ribosomal protein S17 Ribosomal_S17_N (PF16205, IPR032440): Ribosomal_S17 N-terminal |
231 |
RPS14 | interactor | 34 | 0.781 | 14.173 | Ribosomal_S11 (PF00411, IPR001971): Ribosomal protein S11 |
232 |
RPS15A | interactor | 36 | 0.706 | 33.194 | Ribosomal_S8 (PF00410, IPR000630): Ribosomal protein S8 |
233 |
RPS17 | interactor | 21 | 0.905 | 1.348 | Ribosomal_S17e (PF00833, IPR001210): Ribosomal S17 |
234 |
RPS2 | interactor | 44 | 0.564 | 142.957 | Ribosomal_S5 (PF00333, IPR013810): Ribosomal protein S5, N-terminal domain Ribosomal_S5_C (PF03719, IPR005324): Ribosomal protein S5, C-terminal domain |
235 |
RPS27 | interactor | 30 | 0.848 | 6.648 | Ribosomal_S27e (PF01667, IPR000592): Ribosomal protein S27 DUF3795 (PF12675, IPR024227): Protein of unknown function (DUF3795) |
236 |
RPS27L | interactor | 20 | 0.774 | 10.494 | E7 (PF00527, IPR000148): E7 protein, Early protein Ribosomal_S27e (PF01667, IPR000592): Ribosomal protein S27 zf-C2HC5 (PF06221, IPR009349): Putative zinc finger motif, C2HC5-type DUF3382 (PF11862, IPR021807): Domain of unknown function (DUF3382) |
237 |
RPS3 | interactor | 45 | 0.579 | 106.594 | KH_2 (PF07650, IPR004044): KH domain Ribosomal_S3_C (PF00189, IPR001351): Ribosomal protein S3, C-terminal domain |
238 |
RPS3A | interactor | 41 | 0.668 | 40.722 | Ribosomal_S3Ae (PF01015, IPR001593): Ribosomal S3Ae family |
239 |
RPS5 | interactor | 33 | 0.708 | 26.098 | Ribosomal_S7 (PF00177, IPR023798): Ribosomal protein S7p/S5e |
240 |
RPS6 | interactor | 39 | 0.692 | 39.164 | Ribosomal_S6e (PF01092, IPR001377): Ribosomal protein S6e DUF4574 (PF15141, IPR027896): Domain of unknown function (DUF4574) |
241 |
RPS9 | interactor | 34 | 0.758 | 17.940 | Ribosomal_S4 (PF00163, IPR001912): Ribosomal protein S4/S9 N-terminal domain S4 (PF01479, IPR002942, SM00363): S4 domain |
242 |
RPSA | interactor | 39 | 0.568 | 97.144 | Ribosomal_S2 (PF00318, IPR001865): Ribosomal protein S2 40S_SA_C (PF16122, IPR032281): 40S ribosomal protein SA C-terminus |
243 |
RWDD3 | interactor | 2 | 1.000 | 0 | DUF1115 (PF06544, IPR010541): Protein of unknown function (DUF1115) RWD (PF05773, IPR006575, SM00591): RWD domain |
244 |
SAP130 | interactor | 8 | 0.536 | 4.672 | SAP130_C (PF16014, IPR031963): Histone deacetylase complex subunit SAP130 C-terminus |
245 |
SARNP | oncoprotein | 4 | 0.500 | 1.368 | SAP (PF02037, IPR003034, SM00513): SAP domain HTH_Tnp_IS630 (PF01710, IPR002622): Transposase Prok-E2_A (PF14457, IPR032865): Prokaryotic E2 family A |
246 |
SAT2 | interactor | 5 | 0.833 | 0.667 | Acetyltransf_1 (PF00583, IPR000182): Acetyltransferase (GNAT) family |
247 |
SIRT1 | oncoprotein | 25 | 0.326 | 98.274 | DUF592 (PF04574, IPR007654): Protein of unknown function (DUF592) SIR2 (PF02146, IPR003000): Sir2 family TPP_enzyme_M (PF00205, IPR012000): Thiamine pyrophosphate enzyme, central domain |
248 |
SKP2 | oncoprotein | 21 | 0.343 | 63.840 | LRR_1 (PF00560, IPR001611): Leucine Rich Repeat LRR_2 (PF07723, IPR013101): Leucine Rich Repeat LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies) F-box-like (PF12937, IPR001810): F-box-like LRR_6 (PF13516, IPR001611): Leucine Rich repeat LRR_8 (PF13855, IPR001611): Leucine rich repeat |
249 |
SLC2A1 | interactor | 2 | 1.000 | 0 | Sugar_tr (PF00083, IPR005828): Sugar (and other) transporter |
250 |
SLC3A2 | interactor | 5 | 0.600 | 2.500 | Alpha-amylase (PF00128, IPR006047): Alpha amylase, catalytic domain DUF3459 (PF11941, IPR022567): Domain of unknown function (DUF3459) SLC3A2_N (PF16028, IPR031984): Solute carrier family 3 member 2 N-terminus |
251 |
SNRNP70 | interactor | 19 | 0.596 | 14.042 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MIP-T3 (PF10243): Microtubule-binding protein MIP-T3 U1snRNP70_N (PF12220, IPR022023): U1 small nuclear ribonucleoprotein of 70kDa MW N terminal |
252 |
SOCS1 | oncoprotein | 7 | 0.476 | 6.352 | SH2 (PF00017, IPR000980, SM00252): SH2 domain SOCS_box (PF07525, IPR001496): SOCS box |
253 |
SOCS3 | suppressor | 11 | 0.364 | 17.730 | SH2 (PF00017, IPR000980, SM00252): SH2 domain SOCS_box (PF07525, IPR001496): SOCS box |
254 |
SON | interactor | 5 | 0.400 | 3.321 | Asp-B-Hydro_N (PF05279, IPR007943): Aspartyl beta-hydroxylase N-terminal region G-patch (PF01585, IPR000467, SM00443): G-patch domain tRNA_synt_1c_R2 (PF04557, IPR007638): Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 Eapp_C (PF10238, IPR019370): E2F-associated phosphoprotein DND1_DSRM (PF14709): double strand RNA binding domain from DEAD END PROTEIN 1 GREB1 (PF15782, IPR028422): Gene regulated by oestrogen in breast cancer RSRP (PF17069): Arginine/Serine-Rich protein 1 |
255 |
SP1 | protein found in more fusions | 29 | 0.339 | 117.106 | zf-Di19 (PF05605, IPR008598): Drought induced 19 protein (Di19), zinc-binding Herpes_capsid (PF06112, IPR009299): Gammaherpesvirus capsid protein zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type Miga (PF10265, IPR019392): Mitoguardin zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 |
256 |
SPRY2 | suppressor | 10 | 0.250 | 25.000 | KAR9 (PF08580, IPR013889): Yeast cortical protein KAR9 Sprouty (PF05210, IPR007875): Sprouty protein (Spry) |
257 |
STK16 | interactor | 5 | 0.500 | 3.000 | Pkinase (PF00069, IPR000719): Protein kinase domain |
258 |
STK38 | interactor | 4 | 0.667 | 0.286 | MEKHLA (PF08670, IPR013978): MEKHLA domain Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain |
259 |
STUB1 | suppressor | 24 | 0.332 | 76.618 | U-box (PF04564, IPR003613, SM00504): U-box domain ANAPC3 (PF12895): Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 (PF13414, IPR011990): TPR repeat TPR_20 (PF14561): Tetratricopeptide repeat |
260 |
TAGLN2 | interactor | 10 | 0.422 | 10.050 | Calponin (PF00402, IPR000557): Calponin family repeat CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain |
261 |
TARDBP | interactor | 53 | 0.397 | 217.880 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
262 |
TARS | interactor | 9 | 0.389 | 12.296 | HGTP_anticodon (PF03129, IPR004154): Anticodon binding domain TGS (PF02824, IPR004095): TGS domain tRNA-synt_2b (PF00587, IPR002314): tRNA synthetase class II core domain (G, H, P, S and T) tRNA_SAD (PF07973, IPR012947, SM00863): Threonyl and Alanyl tRNA synthetase second additional domain |
263 |
TCEB1 | interactor | 27 | 0.262 | 166.689 | Skp1_POZ (PF03931, IPR016073): Skp1 family, tetramerisation domain |
264 |
TCEB2 | interactor | 22 | 0.338 | 81.501 | ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family |
265 |
TCEB3 | suppressor | 7 | 0.476 | 8.900 | Elongin_A (PF06881, IPR010684): RNA polymerase II transcription factor SIII (Elongin) subunit A Med26 (PF08711, IPR017923): TFIIS helical bundle-like domain |
266 |
TCP1 | interactor | 22 | 0.615 | 22.846 | Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family |
267 |
TGFB1I1 | interactor | 2 | 1.000 | 0 | LIM (PF00412, IPR001781, SM00132): LIM domain Paxillin (PF03535): Paxillin family |
268 |
TGM2 | protein found in more fusions | 12 | 0.345 | 25.419 | Transglut_C (PF00927, IPR008958): Transglutaminase family, C-terminal ig like domain Transglut_N (PF00868, IPR001102): Transglutaminase family Transglut_core (PF01841, IPR002931, SM00460): Transglutaminase-like superfamily |
269 |
TOP2A | oncoprotein | 17 | 0.426 | 23.808 | DNA_gyraseB (PF00204, IPR013506): DNA gyrase B DTHCT (PF08070, IPR012542): DTHCT (NUC029) region HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Sec62 (PF03839, IPR004728): Translocation protein Sec62 Toprim (PF01751, IPR006171, SM00493): Toprim domain DNA_topoisoIV (PF00521, IPR002205, SM00434): DNA gyrase/topoisomerase IV, subunit A PHC2_SAM_assoc (PF16616): Unstructured region on Polyhomeotic-like protein 1 and 2 TOPRIM_C (PF16898, IPR031660): C-terminal associated domain of TOPRIM |
270 |
TP53 | oncoprotein | 101 | 0.173 | 2140.709 | DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region P53 (PF00870, IPR011615): P53 DNA-binding domain P53_tetramer (PF07710, IPR010991): P53 tetramerisation motif |
271 |
TPT1 | interactor | 4 | 0.667 | 0.183 | TCTP (PF00838, IPR018105): Translationally controlled tumour protein |
272 |
TRAFD1 | interactor | 3 | 1.000 | 0 | zf-Di19 (PF05605, IPR008598): Drought induced 19 protein (Di19), zinc-binding DM (PF00751, IPR001275, SM00301): DM DNA binding domain zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-C2H2_4 (PF13894): C2H2-type zinc finger zf-C2HC_2 (PF13913): zinc-finger of a C2HC-type |
273 |
TRIM28 | protein found in more fusions | 36 | 0.277 | 232.137 | ASFV_J13L (PF05568, IPR008385): African swine fever virus J13L protein K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain PHD (PF00628, IPR019787, SM00249): PHD-finger FYVE_2 (PF02318, IPR010911): FYVE-type zinc finger zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger zf-RING_5 (PF14634, IPR001841): zinc-RING finger domain SKA2 (PF16740, IPR026762): Spindle and kinetochore-associated protein 2 |
274 |
TRIP12 | interactor | 6 | 0.533 | 1.752 | Alpha_GJ (PF03229, IPR004913): Alphavirus glycoprotein J Ndc1_Nup (PF09531, IPR019049): Nucleoporin protein Ndc1-Nup WWE (PF02825, IPR004170, SM00678): WWE domain SOG2 (PF10428, IPR019487): RAM signalling pathway protein HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase) UNC45-central (PF11701, IPR024660): Myosin-binding striated muscle assembly central HEAT_2 (PF13646): HEAT repeats |
275 |
TUBA1A | oncoprotein | 12 | 0.515 | 11.149 | Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain |
276 |
TUBA3C | interactor | 5 | 0.700 | 0.887 | Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain |
277 |
TUBA3D | interactor | 4 | 0.500 | 0.476 | Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain |
278 |
TUBA3E | interactor | 5 | 0.700 | 2.000 | Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain |
279 |
TUBA4A | interactor | 15 | 0.638 | 6.698 | Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain |
280 |
TUBB4B | interactor | 21 | 0.376 | 47.400 | Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain |
281 |
TXN | oncoprotein | 11 | 0.545 | 8.258 | Thioredoxin (PF00085, IPR013766): Thioredoxin |
282 |
UBC | protein found in more fusions | 68 | 0.178 | 1088.932 | ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family |
283 |
UBE2D1 | interactor | 16 | 0.400 | 30.379 | UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme |
284 |
UBE2D2 | oncoprotein | 13 | 0.409 | 20.660 | UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme |
285 |
UBR5 | protein found in more fusions | 8 | 0.667 | 3.219 | CENP-B_dimeris (PF09026, IPR015115): Centromere protein B dimerisation domain SDA1 (PF05285, IPR007949): SDA1 HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase) PABP (PF00658, IPR002004, SM00517): Poly-adenylate binding protein, unique domain E3_UbLigase_EDD (PF11547, IPR024725): E3 ubiquitin ligase EDD PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term DUF3915 (PF13054, IPR025026): Protein of unknown function (DUF3915) RCDG1 (PF15725, IPR031457): Renal cancer differentiation gene 1 protein |
286 |
UBXN7 | interactor | 13 | 0.526 | 17.545 | UBX (PF00789, IPR001012, SM00166): UBX domain UIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif Thioredoxin_7 (PF13899): Thioredoxin-like UBA_4 (PF14555): UBA-like domain |
287 |
USP20 | protein found in more fusions | 9 | 0.357 | 15.633 | UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase zf-UBP (PF02148, IPR001607, SM00290): Zn-finger in ubiquitin-hydrolases and other protein DUSP (PF06337, IPR006615, SM00695): DUSP domain |
288 |
USP33 | suppressor | 9 | 0.417 | 9.568 | UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase zf-UBP (PF02148, IPR001607, SM00290): Zn-finger in ubiquitin-hydrolases and other protein DUSP (PF06337, IPR006615, SM00695): DUSP domain |
289 |
UXT | interactor | 3 | 0.667 | 0.400 | Prefoldin (PF02996, IPR004127): Prefoldin subunit |
290 |
VAPB | interactor | 6 | 0.600 | 4.233 | ATP-synt_G (PF04718, IPR006808): Mitochondrial ATP synthase g subunit ZapB (PF06005, IPR009252): Cell division protein ZapB Motile_Sperm (PF00635, IPR000535): MSP (Major sperm protein) domain |
291 |
VBP1 | interactor | 8 | 0.250 | 16.319 | Prefoldin (PF02996, IPR004127): Prefoldin subunit |
292 |
WTIP | interactor | 1 | 0 | 0 | DUF983 (PF06170, IPR009325): Protein of unknown function (DUF983) LIM (PF00412, IPR001781, SM00132): LIM domain |
293 |
XRCC5 | suppressor | 20 | 0.415 | 27.274 | Ku (PF02735, IPR006164, SM00559): Ku70/Ku80 beta-barrel domain Ku_C (PF03730, IPR005160): Ku70/Ku80 C-terminal arm Ku_N (PF03731, IPR005161): Ku70/Ku80 N-terminal alpha/beta domain Ku_PK_bind (PF08785, IPR014893): Ku C terminal domain like |
294 |
YY1AP1 | interactor | 1 | 0 | 0 | CtnDOT_TraJ (PF07863, IPR012424): Homologues of TraJ from Bacteroides conjugative transposon JAKMIP_CC3 (PF16034, IPR031994): JAKMIP CC3 domain |
295 |
ZNF197 | interactor | 3 | 1.000 | 0 | KRAB (PF01352, IPR001909, SM00349): KRAB box SCAN (PF02023, IPR003309, SM00431): SCAN domain zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_4 (PF13894): C2H2-type zinc finger |
296 |
ZNF350 | interactor | 3 | 0.667 | 0.143 | KRAB (PF01352, IPR001909, SM00349): KRAB box zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain |
297 |
ZNF512B | interactor | 6 | 0.533 | 3.117 | YTV (PF07639, IPR011521): YTV zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-C2HC5 (PF06221, IPR009349): Putative zinc finger motif, C2HC5-type zf-Nse (PF11789, IPR004181): Zinc-finger of the MIZ type in Nse subunit Zn_Tnp_IS1595 (PF12760, IPR024442): Transposase zinc-ribbon domain zf-C2H2_4 (PF13894): C2H2-type zinc finger zf-C2H2_aberr (PF17017, IPR031514): Aberrant zinc-finger |
298 |
ZYX | suppressor | 7 | 0.429 | 7.242 | DUF1180 (PF06679, IPR009565): Protein of unknown function (DUF1180) LIM (PF00412, IPR001781, SM00132): LIM domain DUF2757 (PF10955, IPR020115): Protein of unknown function (DUF2757) |