Find Fusion Network

Visualization interactions

Powered by Cytoscape Web for: VHL (from a repository: Thu Nov 10 14:59:26 2016)

Examples AFF1 MLL ACTN4 + MLLAFF1 + MLLALK + MSNALK + TFGALK + TPM3ALK + TPM4ASXL2 + KAT6AATF1 + FUSBCR + ABL1BCR + FGFR1CCND1 + TACSTD2CD74 + ROS1CDK6 + MLLCOL1A1 + PDGFBCREB3L2 + PPARGCREB3L2 + FUSCREBBP + KAT6ADAZAP1 + MEF2DELL + MLLEPS15 + MLLERG + EWSR1ERG + FUSERG + TMPRSS2ETV5 + TMPRSS2ETV6 + ABL1ETV6 + NTRK3ETV6 + PAX5EWSR1 + FLI1EWSR1 + WT1FOXO1 + PAX3FOXP1 + PAX5FRYL + MLLGAS7 + MLLGMPS + MLLGOLGA5 + RETHOOK3 + RETHOXC13 + NUP98HOXD13 + NUP98MECOM + RUNX1MKL1 + RBM15MLL + MLLT1MLL + MLLT4MLL + MLLT10MLL + PICALMMLLT10 + PICALMNCOA1 + PAX3NIN + PDGFRBNPM1 + RARANRG1 + ODZ4NTRK1 + TFGNUMA1 + RARANUP98 + PHF23PAX5 + ZNF521PBX1 + TCF3RET + TRIM27ROS1 + SLC34A2PML + RARAPRKAR1A + RARAPRKAR1A + RETRUNX1 + RUNX1T1RUNX1 + SH3D19	Cytoscape Web will replace the contents your graph	PPI Properties: Click on nodes or edges
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Statistics and Network structure information

Statistic of PPI Value(s) The number of interactors (fusion and proteins) 298 The number (and %) of the onco-proteins 101 (33.89 %) The number (and %) of the tumor suppressors 25 (8.39 %) Total number of binary PPIs (saturation %) 2617 (5.91 %) The number (and %) of affected PPIs 298 (11.39 %) The number of possible different fusions 55 PPI diameter 2 PPI radius 1 The average degree of PPI 16.886 Assortativity coefficient -0.2475 The network average Clustering coefficient 0.543 The number (and %) of a zero Clustering coefficients 17 (5.70 %) The number (and %) of a zero Betweenness Centrality 54 (18.12 %)

ACTIVE INTERACTORS

List of the fusions
PPI for parental proteins: VHL	All fusions : CA391692;
Proteins found in more fusions	ID3 (see 1 fusions); PSMB3 (see 1 fusions); VHL (see 1 fusions); PRDX1 (see 1 fusions); HIF1AN (see 1 fusions); EP300 (see 1 fusions); PLOD3 (see 2 fusions); COL4A2 (see 1 fusions); DDX5 (see 1 fusions); APP (see 4 fusions); HSP90AA1 (see 2 fusions); HNRNPLL (see 1 fusions); JAK2 (see 3 fusions); PLOD2 (see 1 fusions); COL4A1 (see 3 fusions); RBPMS (see 2 fusions); IMPDH2 (see 2 fusions); HNRNPD (see 1 fusions); FKBP8 (see 1 fusions); STUB1 (see 1 fusions); POLR2A (see 2 fusions); CSNK2A1 (see 1 fusions); DDX17 (see 3 fusions); EPAS1 (see 1 fusions); TGM2 (see 4 fusions); EGLN1 (see 1 fusions); NCL (see 3 fusions); PRKCD (see 2 fusions); IVNS1ABP (see 2 fusions); MYC (see 1 fusions); UBE2D2 (see 2 fusions); KAT2B (see 1 fusions); ACTB (see 2 fusions); COPS5 (see 1 fusions); RACK1/FN1 (see 1 fusions); PARP1 (see 1 fusions); UBC (see 1 fusions); CLU (see 5 fusions); TP53 (see 3 fusions); ALAS1 (see 1 fusions); PRKCH (see 1 fusions); MCM7 (see 2 fusions); CHMP2B (see 1 fusions); TRIM28 (see 1 fusions); RHOBTB3 (see 1 fusions); SP1 (see 1 fusions); HNRNPL (see 2 fusions); USP20 (see 1 fusions); UBR5 (see 4 fusions); RACK1 (see 3 fusions); RALYL (see 1 fusions); KAT5 (see 3 fusions); HNRNPC (see 1 fusions); PCGF2 (see 1 fusions);

List of active interactors

#	Name	Type	Number of PPI (degree)	Clustering Coefficient	Betweenness Centrality	Domains (Pfam, InterPro, SMART): description
1	VHL	parental protein	298	0.050	61568.247	Trypan_PARP (PF05887, IPR008882): Procyclic acidic repetitive protein (PARP) VHL (PF01847, IPR022772): von Hippel-Lindau disease tumour suppressor protein VHL_C (PF17211): VHL box domain
2	ACTB	oncoprotein	28	0.444	52.113	Actin (PF00022, IPR004000, SM00268): Actin
3	ADRB2	interactor	19	0.373	44.891	7tm_1 (PF00001, IPR000276): 7 transmembrane receptor (rhodopsin family)
4	AJUBA	oncoprotein	2	1.000	0	LIM (PF00412, IPR001781, SM00132): LIM domain
5	ALAS1	protein found in more fusions	3	1.000	0	Aminotran_1_2 (PF00155, IPR004839): Aminotransferase class I and II Preseq_ALAS (PF09029, IPR015118): 5-aminolevulinate synthase presequence
6	ANKRD40	interactor	4	0.667	0.167	Ank_4 (PF13637): Ankyrin repeats (many copies) Ank_5 (PF13857): Ankyrin repeats (many copies)
7	APP	protein found in more fusions	55	0.112	947.952	APP_N (PF02177, IPR015849, SM00006): Amyloid A4 N-terminal heparin-binding Beta-APP (PF03494, IPR013803): Beta-amyloid peptide (beta-APP) BUD22 (PF09073, IPR015158): BUD22 IncA (PF04156, IPR007285): IncA protein Kunitz_BPTI (PF00014, IPR002223, SM00131): Kunitz/Bovine pancreatic trypsin inhibitor domain APP_amyloid (PF10515, IPR019543): beta-amyloid precursor protein C-terminus APP_Cu_bd (PF12924, IPR011178): Copper-binding of amyloid precursor, CuBD APP_E2 (PF12925, IPR024329): E2 domain of amyloid precursor protein
8	APRT	interactor	3	0.667	0.083	Pribosyltran (PF00156, IPR000836): Phosphoribosyl transferase domain
9	AR	oncoprotein	28	0.248	157.080	Androgen_recep (PF02166, IPR001103): Androgen receptor zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
10	ASTL	interactor	2	1.000	0	Astacin (PF01400, IPR001506): Astacin (Peptidase family M12A)
11	ATM	oncoprotein	18	0.360	41.820	FAT (PF02259, IPR003151): FAT domain FATC (PF02260, IPR003152): FATC domain HEAT (PF02985, IPR000357): HEAT repeat PI3_PI4_kinase (PF00454, IPR000403, SM00146): Phosphatidylinositol 3- and 4-kinase TAN (PF11640, IPR021668): Telomere-length maintenance and DNA damage repair ANAPC5 (PF12862, IPR026000): Anaphase-promoting complex subunit 5
12	ATXN2	interactor	5	0.700	0.872	LsmAD (PF06741, IPR009604): LsmAD domain PAM2 (PF07145, IPR009818): Ataxin-2 C-terminal region DUF3446 (PF11928, IPR021849): Domain of unknown function (DUF3446) Spt20 (PF12090, IPR021950): Spt20 family SM-ATX (PF14438, IPR025852): Ataxin 2 SM domain
13	AURKA	oncoprotein	39	0.279	219.696	Pkinase (PF00069, IPR000719): Protein kinase domain MTBP_C (PF14920, IPR029418): MDM2-binding
14	BCL2L11	oncoprotein	7	0.524	2.450	Bclx_interact (PF08945, IPR015040): Bcl-x interacting, BH3 domain Bim_N (PF06773, IPR014771): Bim protein N-terminus
15	BCL2L14	interactor	2	1.000	0	Bcl-2 (PF00452, IPR026298): Apoptosis regulator proteins, Bcl-2 family CF222 (PF15661, IPR031362): C6orf222, uncharacterised family
16	BSG	interactor	7	0.286	13.067	Ig_2 (PF13895, IPR007110): Immunoglobulin domain Ig_3 (PF13927): Immunoglobulin domain Izumo-Ig (PF16706, IPR032699): Izumo-like Immunoglobulin domain
17	C1QB	interactor	3	0.667	1.000	C1q (PF00386, IPR001073, SM00110): C1q domain Collagen (PF01391, IPR008160): Collagen triple helix repeat (20 copies)
18	C1QTNF2	interactor	2	1.000	0	C1q (PF00386, IPR001073, SM00110): C1q domain Collagen (PF01391, IPR008160): Collagen triple helix repeat (20 copies) DUF1860 (PF08949, IPR015044): Domain of unknown function (DUF1860)
19	CAB39	interactor	5	0.500	4.333	Mo25 (PF08569, IPR013878): Mo25-like
20	CAPN7	interactor	1	0	0	Calpain_III (PF01067, IPR022682, SM00720): Calpain large subunit, domain III MIT (PF04212, IPR007330, SM00745): MIT (microtubule interacting and transport) domain Peptidase_C2 (PF00648, IPR001300, SM00230): Calpain family cysteine protease
21	CAPZB	interactor	8	0.607	3.159	Cytochrom_B562 (PF07361, IPR009155): Cytochrome b562 F_actin_cap_B (PF01115, IPR001698): F-actin capping protein, beta subunit
22	CARD9	interactor	3	1.000	0	CARD (PF00619, IPR001315, SM00114): Caspase recruitment domain HALZ (PF02183, IPR003106, SM00340): Homeobox associated leucine zipper IncA (PF04156, IPR007285): IncA protein NPV_P10 (PF05531, IPR008702): Nucleopolyhedrovirus P10 protein
23	CBR1	interactor	4	0.667	1.167	adh_short (PF00106, IPR002198): short chain dehydrogenase
24	CBX1	interactor	6	0.700	1.200	Chromo (PF00385, IPR023780, SM00298): Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow (PF01393, IPR008251, SM00300): Chromo shadow domain
25	CBX3	interactor	9	0.500	6.540	Chromo (PF00385, IPR023780, SM00298): Chromo (CHRromatin Organisation MOdifier) domain DTHCT (PF08070, IPR012542): DTHCT (NUC029) region Chromo_shadow (PF01393, IPR008251, SM00300): Chromo shadow domain
26	CBX5	suppressor	14	0.295	37.045	Chromo (PF00385, IPR023780, SM00298): Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow (PF01393, IPR008251, SM00300): Chromo shadow domain
27	CCDC59	interactor	3	0.667	0.500	rRNA_processing (PF08524, IPR013730): rRNA processing
28	CCDC82	interactor	1	0	0	RNA_pol_3_Rpc31 (PF11705, IPR024661): DNA-directed RNA polymerase III subunit Rpc31 Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal DUF4196 (PF13846, IPR025244): Domain of unknown function (DUF4196) DUF4211 (PF13926, IPR025451): Domain of unknown function (DUF4211)
29	CCT2	interactor	24	0.583	33.952	Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
30	CCT3	interactor	21	0.600	34.048	Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
31	CCT4	interactor	21	0.605	19.896	Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
32	CCT5	interactor	24	0.507	58.271	Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
33	CCT6A	interactor	18	0.706	10.332	Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
34	CCT7	interactor	20	0.595	24.627	Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
35	CCT8	interactor	19	0.719	9.365	Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
36	CD44	oncoprotein	7	0.429	6.145	VP4_2 (PF08935, IPR015031): Viral protein VP4 subunit Xlink (PF00193, IPR000538, SM00445): Extracellular link domain S36_mt (PF10937, IPR020373): Ribosomal protein S36, mitochondrial
37	CDC34	oncoprotein	9	0.643	2.458	UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
38	CDK2	oncoprotein	81	0.185	1367.577	Kdo (PF06293, IPR010440): Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase (PF00069, IPR000719): Protein kinase domain
39	CDKN2A	oncoprotein	27	0.390	76.119	Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_5 (PF13857): Ankyrin repeats (many copies)
40	CDO1	interactor	1	0	0	CDO_I (PF05995, IPR010300): Cysteine dioxygenase type I
41	CER1	interactor	3	1.000	0	DAN (PF03045, IPR004133): DAN domain
42	CERKL	interactor	1	0	0	DAGK_cat (PF00781, IPR001206, SM00046): Diacylglycerol kinase catalytic domain
43	CHEK2	oncoprotein	11	0.533	8.295	FHA (PF00498, IPR000253, SM00240): FHA domain Pkinase (PF00069, IPR000719): Protein kinase domain
44	CHMP2B	protein found in more fusions	2	0	0	Involucrin (PF00904, IPR000354): Involucrin repeat Snf7 (PF03357, IPR005024): Snf7
45	CLU	oncoprotein	5	0.667	0.310	Clusterin (PF01093, IPR000753): Clusterin
46	CMC2	interactor	1	0	0	Cmc1 (PF08583, IPR013892): Cytochrome c oxidase biogenesis protein Cmc1 like Pet191_N (PF10203, IPR018793): Cytochrome c oxidase assembly protein PET191
47	CNTF	interactor	3	1.000	0	CNTF (PF01110, IPR000151): Ciliary neurotrophic factor
48	COL4A1	protein found in more fusions	4	0.667	1.000	C4 (PF01413, IPR001442, SM00111): C-terminal tandem repeated domain in type 4 procollagen Collagen (PF01391, IPR008160): Collagen triple helix repeat (20 copies) DUF1860 (PF08949, IPR015044): Domain of unknown function (DUF1860)
49	COL4A2	protein found in more fusions	6	0.400	6.000	C4 (PF01413, IPR001442, SM00111): C-terminal tandem repeated domain in type 4 procollagen Collagen (PF01391, IPR008160): Collagen triple helix repeat (20 copies) DUF1860 (PF08949, IPR015044): Domain of unknown function (DUF1860)
50	COL4A3	interactor	1	0	0	C4 (PF01413, IPR001442, SM00111): C-terminal tandem repeated domain in type 4 procollagen Collagen (PF01391, IPR008160): Collagen triple helix repeat (20 copies) DUF1860 (PF08949, IPR015044): Domain of unknown function (DUF1860)
51	COL4A5	interactor	2	1.000	0	C4 (PF01413, IPR001442, SM00111): C-terminal tandem repeated domain in type 4 procollagen Collagen (PF01391, IPR008160): Collagen triple helix repeat (20 copies) DUF1860 (PF08949, IPR015044): Domain of unknown function (DUF1860)
52	COL4A6	interactor	2	1.000	0	C4 (PF01413, IPR001442, SM00111): C-terminal tandem repeated domain in type 4 procollagen Collagen (PF01391, IPR008160): Collagen triple helix repeat (20 copies)
53	COL6A1	interactor	2	1.000	0	Collagen (PF01391, IPR008160): Collagen triple helix repeat (20 copies) VWA (PF00092, IPR002035, SM00327): von Willebrand factor type A domain
54	COL9A1	interactor	3	0.667	1.000	Collagen (PF01391, IPR008160): Collagen triple helix repeat (20 copies) DUF826 (PF05696, IPR008544): Protein of unknown function (DUF826) Laminin_G_2 (PF02210, IPR001791): Laminin G domain
55	COLGALT1	interactor	5	0.500	2.900	Glyco_transf_25 (PF01755, IPR002654): Glycosyltransferase family 25 (LPS biosynthesis protein) Glyco_tranf_2_4 (PF13704): Glycosyl transferase family 2
56	COPS5	protein found in more fusions	93	0.236	1270.114	JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease
57	CRTAP	interactor	2	1.000	0	Whi5 (PF08528, IPR013734): Whi5 like YfiO (PF13525): Outer membrane lipoprotein Stomagen (PF16851, IPR031753): Stomagen
58	CSNK2A1	oncoprotein	37	0.302	176.679	Pkinase (PF00069, IPR000719): Protein kinase domain
59	CSTB	oncoprotein	5	0.400	4.900	Cystatin (PF00031, IPR000010, SM00043): Cystatin domain
60	CSTF3	interactor	3	0.667	0.143	NRDE-2 (PF08424, IPR013633): NRDE-2, necessary for RNA interference Suf (PF05843, IPR008847): Suppressor of forked protein (Suf) TPR_6 (PF13174, IPR019734): Tetratricopeptide repeat TPR_14 (PF13428): Tetratricopeptide repeat TPR_19 (PF14559): Tetratricopeptide repeat
61	CUL2	suppressor	81	0.226	1092.756	Cullin (PF00888, IPR001373, SM00182): Cullin family Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
62	CUL5	suppressor	62	0.298	417.501	Cullin (PF00888, IPR001373, SM00182): Cullin family GlutR_dimer (PF00745, IPR015896): Glutamyl-tRNAGlu reductase, dimerisation domain Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
63	CYBA	interactor	3	0.667	0.400	Cytochrom_B558a (PF05038, IPR007732): Cytochrome Cytochrome b558 alpha-subunit
64	DACT1	suppressor	3	0.667	0.500	Dapper (PF15268, IPR024843): Dapper
65	DACT2	interactor	1	0	0	Dapper (PF15268, IPR024843): Dapper
66	DCUN1D1	interactor	40	0.391	158.809	Cullin_binding (PF03556, IPR005176): Cullin binding UBA_4 (PF14555): UBA-like domain
67	DDX17	protein found in more fusions	32	0.383	102.200	CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal DEAD (PF00270, IPR011545): DEAD/DEAH box helicase Ferritin (PF00210, IPR008331): Ferritin-like domain GRP (PF07172, IPR010800): Glycine rich protein family Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
68	DDX3X	suppressor	24	0.467	45.628	DEAD (PF00270, IPR011545): DEAD/DEAH box helicase DUF755 (PF05501, IPR008474): Domain of unknown function (DUF755) Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
69	DDX3Y	interactor	1	0	0	DEAD (PF00270, IPR011545): DEAD/DEAH box helicase Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
70	DDX5	oncoprotein	30	0.448	66.209	DEAD (PF00270, IPR011545): DEAD/DEAH box helicase P68HR (PF08061, IPR012587): P68HR (NUC004) repeat ResIII (PF04851, IPR006935): Type III restriction enzyme, res subunit Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
71	DGKI	interactor	1	0	0	Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain) DAGK_acc (PF00609, IPR000756, SM00045): Diacylglycerol kinase accessory domain DAGK_cat (PF00781, IPR001206, SM00046): Diacylglycerol kinase catalytic domain Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_4 (PF13637): Ankyrin repeats (many copies)
72	DGKZ	interactor	3	0.667	1.000	C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain) DAGK_acc (PF00609, IPR000756, SM00045): Diacylglycerol kinase accessory domain DAGK_cat (PF00781, IPR001206, SM00046): Diacylglycerol kinase catalytic domain Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_4 (PF13637): Ankyrin repeats (many copies)
73	DNAJA1	interactor	18	0.516	29.958	DnaJ (PF00226, IPR001623, SM00271): DnaJ domain DnaJ_C (PF01556, IPR002939): DnaJ C terminal domain
74	DNAJA2	interactor	15	0.581	9.412	DnaJ (PF00226, IPR001623, SM00271): DnaJ domain DnaJ_C (PF01556, IPR002939): DnaJ C terminal domain
75	DNAJA3	suppressor	11	0.491	18.828	DnaJ (PF00226, IPR001623, SM00271): DnaJ domain DnaJ_C (PF01556, IPR002939): DnaJ C terminal domain
76	DVL2	interactor	10	0.444	14.144	DEP (PF00610, IPR000591, SM00049): Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Dishevelled (PF02377, IPR003351): Dishevelled specific domain PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) DIX (PF00778, IPR001158, SM00021): DIX domain Dsh_C (PF12316, IPR024580): Segment polarity protein dishevelled (Dsh) C terminal
77	E2F1	oncoprotein	17	0.471	21.297	Cellsynth_D (PF03500, IPR022798): Cellulose synthase subunit D E2F_TDP (PF02319, IPR003316): E2F/DP family winged-helix DNA-binding domain E2F_CC-MB (PF16421, IPR032198): E2F transcription factor CC-MB domain
78	EEF1B2	interactor	13	0.424	13.400	EF1_GNE (PF00736, IPR014038, SM00888): EF-1 guanine nucleotide exchange domain EF-1_beta_acid (PF10587, IPR018940): Eukaryotic elongation factor 1 beta central acidic region GST_C_6 (PF17171): Glutathione S-transferase, C-terminal domain
79	EGLN1	oncoprotein	13	0.258	41.289	zf-MYND (PF01753, IPR002893): MYND finger 2OG-FeII_Oxy_3 (PF13640, IPR005123): 2OG-Fe(II) oxygenase superfamily
80	EIF5A	interactor	7	0.667	2.001	EFP_N (PF08207, IPR013185): Elongation factor P (EF-P) KOW-like domain eIF-5a (PF01287, IPR020189): Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold
81	EIF5A2	interactor	4	0.833	0.500	EFP_N (PF08207, IPR013185): Elongation factor P (EF-P) KOW-like domain eIF-5a (PF01287, IPR020189): Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold
82	ELAVL1	oncoprotein	53	0.186	690.671	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
83	EP300	oncoprotein	35	0.308	169.143	Creb_binding (PF09030, IPR014744): Creb binding DUF902 (PF06001, IPR010303): Domain of Unknown Function (DUF902) Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region KIX (PF02172, IPR003101): KIX domain RR_TM4-6 (PF06459, IPR009460): Ryanodine Receptor TM 4-6 TPX2 (PF06886, IPR027329): Targeting protein for Xklp2 (TPX2) zf-TAZ (PF02135, IPR000197, SM00551): TAZ zinc finger HAT_KAT11 (PF08214, IPR013178): Histone acetylation protein Bromodomain (PF00439, IPR001487, SM00297): Bromodomain ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type
84	EPAS1	suppressor	17	0.350	31.332	Corona_I (PF03187, IPR004876): Corona nucleocapsid I protein HIF-1a_CTAD (PF08778, IPR014887): HIF-1 alpha C terminal transactivation domain HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain PAS (PF00989, IPR013767, SM00091): PAS fold HIF-1 (PF11413, IPR021537): Hypoxia-inducible factor-1 PAS_11 (PF14598): PAS domain
85	EPHA4	interactor	3	0.667	0.400	fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain Ephrin_rec_like (PF07699, IPR011641): Putative ephrin-receptor like Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SAM_2 (PF07647, IPR011510): SAM domain (Sterile alpha motif) DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369) Ephrin_lbd (PF01404, IPR001090, SM00615): Ephrin receptor ligand binding domain SusE (PF14292, IPR025970): SusE outer membrane protein EphA2_TM (PF14575, IPR027936): Ephrin type-A receptor 2 transmembrane domain
86	EPOR	oncoprotein	7	0.714	2.919	EpoR_lig-bind (PF09067, IPR015152): Erythropoietin receptor, ligand binding fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
87	EXOSC8	interactor	5	0.833	0.074	RNase_PH (PF01138, IPR001247): 3' exoribonuclease family, domain 1 RNase_PH_C (PF03725, IPR015847): 3' exoribonuclease family, domain 2
88	FASTKD3	interactor	2	1.000	0	FAST_1 (PF06743, IPR010622): FAST kinase-like protein, subdomain 1 FAST_2 (PF08368, IPR013579): FAST kinase-like protein, subdomain 2 NUC205 (PF08168, IPR012584): NUC205 domain RAP (PF08373, IPR013584, SM00952): RAP domain
89	FKBP8	protein found in more fusions	10	0.472	10.669	FKBP_C (PF00254, IPR001179): FKBP-type peptidyl-prolyl cis-trans isomerase TPR_9 (PF13371, IPR011990): Tetratricopeptide repeat TPR_16 (PF13432): Tetratricopeptide repeat Fis1_TPR_C (PF14853, IPR028061): Fis1 C-terminal tetratricopeptide repeat
90	FLNA	suppressor	17	0.368	46.294	CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain Filamin (PF00630, IPR017868): Filamin/ABP280 repeat
91	FN1	oncoprotein	97	0.175	1916.994	fn1 (PF00039, IPR000083, SM00058): Fibronectin type I domain fn2 (PF00040, IPR000562, SM00059): Fibronectin type II domain fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369)
92	FSCN1	oncoprotein	7	0.619	3.387	Fascin (PF06268, IPR022768): Fascin domain
93	FZR1	suppressor	8	0.393	11.165	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
94	GLI1	oncoprotein	9	0.528	6.682	zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain FOXP-CC (PF16159, IPR032354): FOXP coiled-coil domain
95	GOLGA4	interactor	4	0.667	0.917	ACCA (PF03255, IPR001095): Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16) DivIC (PF04977, IPR007060): Septum formation initiator DUF106 (PF01956, IPR002809): Integral membrane protein DUF106 DUF16 (PF01519, IPR002862): Protein of unknown function DUF16 DUF641 (PF04859, IPR006943): Plant protein of unknown function (DUF641) DUF724 (PF05266, IPR007930): Protein of unknown function (DUF724) Fez1 (PF06818): Fez1 FlaC_arch (PF05377, IPR008039): Flagella accessory protein C (FlaC) GRIP (PF01465, IPR000237, SM00755): GRIP domain Mnd1 (PF03962, IPR005647): Mnd1 family Pox_A_type_inc (PF04508, IPR007596): Viral A-type inclusion protein repeat Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein SlyX (PF04102, IPR007236): SlyX Atg14 (PF10186, IPR018791): Vacuolar sorting 38 and autophagy-related subunit 14 XhlA (PF10779, IPR019715): Haemolysin XhlA YlqD (PF11068, IPR021297): YlqD protein ADIP (PF11559, IPR021622): Afadin- and alpha -actinin-Binding DUF4407 (PF14362, IPR025519): Domain of unknown function (DUF4407) CCDC-167 (PF15188, IPR028194): Coiled-coil domain-containing protein 167 PRKG1_interact (PF15898, IPR031775): cGMP-dependent protein kinase interacting domain RecQ_Zn_bind (PF16124, IPR032284): RecQ zinc-binding PKcGMP_CC (PF16808, IPR031831): Coiled-coil N-terminus of cGMP-dependent protein kinase TetR_C_13 (PF16925, IPR011075): Bacterial transcriptional repressor C-terminal
96	GPLD1	interactor	3	1.000	0	FG-GAP (PF01839, IPR013517): FG-GAP repeat Zn_dep_PLPC (PF00882, IPR029002, SM00770): Zinc dependent phospholipase C
97	GRN	oncoprotein	3	0.667	0.500	Granulin (PF00396, IPR000118, SM00277): Granulin Lustrin_cystein (PF14625, IPR028150): Lustrin, cysteine-rich repeated domain
98	GRWD1	interactor	4	1.000	0	Voldacs (PF03517): Regulator of volume decrease after cellular swelling WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat CAF1C_H4-bd (PF12265, IPR022052): Histone-binding protein RBBP4 or subunit C of CAF1 complex
99	HAS1	interactor	1	0	0	Glycos_transf_2 (PF00535, IPR001173): Glycosyl transferase family 2 Glyco_tranf_2_3 (PF13641): Glycosyltransferase like family 2
100	HDAC1	suppressor	43	0.266	314.742	FSAP_sig_propep (PF03032, IPR004275): Frog skin active peptide family signal and propeptide Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
101	HDAC2	oncoprotein	26	0.353	77.704	Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain NARP1 (PF12569, IPR021183): NMDA receptor-regulated protein 1
102	HDAC3	oncoprotein	28	0.328	73.691	Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
103	HIF1A	suppressor	43	0.216	469.895	Dicty_REP (PF05086, IPR007778): Dictyostelium (Slime Mold) REP protein HIF-1a_CTAD (PF08778, IPR014887): HIF-1 alpha C terminal transactivation domain HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain PAS (PF00989, IPR013767, SM00091): PAS fold PAS_3 (PF08447, IPR013655): PAS fold HIF-1 (PF11413, IPR021537): Hypoxia-inducible factor-1
104	HIF1AN	protein found in more fusions	7	0.667	0.860	Cupin_8 (PF13621): Cupin-like domain
105	HIF3A	interactor	2	1.000	0	HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain PAS (PF00989, IPR013767, SM00091): PAS fold Spo0M (PF07070, IPR009776): SpoOM protein HIF-1 (PF11413, IPR021537): Hypoxia-inducible factor-1 PAS_11 (PF14598): PAS domain
106	HIST1H1C	oncoprotein	9	0.694	2.651	Amelin (PF05111, IPR007798, SM00817): Ameloblastin precursor (Amelin) Linker_histone (PF00538, IPR005818, SM00526): linker histone H1 and H5 family DUF4349 (PF14257, IPR025645): Domain of unknown function (DUF4349)
107	HIST1H2BC	interactor	2	1.000	0	Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
108	HIST1H2BL	interactor	3	1.000	0	Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
109	HIST4H4	interactor	11	0.364	14.455	CENP-T_C (PF15511): Centromere kinetochore component CENP-T histone fold
110	HNRNPA1	interactor	57	0.349	404.348	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HnRNPA1 (PF11627, IPR021662): Nuclear factor hnRNPA1
111	HNRNPA2B1	oncoprotein	31	0.473	102.650	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
112	HNRNPA3	oncoprotein	23	0.783	6.272	IATP (PF04568, IPR007648): Mitochondrial ATPase inhibitor, IATP RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
113	HNRNPAB	interactor	17	0.794	3.131	CBFNT (PF08143, IPR012956): CBFNT (NUC161) domain GRP (PF07172, IPR010800): Glycine rich protein family NID (PF07292, IPR009909): Nmi/IFP 35 domain (NID) RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2462 (PF09495, IPR019034): Protein of unknown function (DUF2462)
114	HNRNPC	protein found in more fusions	26	0.453	60.593	APG6 (PF04111, IPR007243): Autophagy protein Apg6 RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SURF2 (PF05477, IPR008833): Surfeit locus protein 2 (SURF2)
115	HNRNPD	oncoprotein	38	0.416	149.871	CBFNT (PF08143, IPR012956): CBFNT (NUC161) domain NID (PF07292, IPR009909): Nmi/IFP 35 domain (NID) RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Keratin_2_head (PF16208, IPR032444): Keratin type II head
116	HNRNPDL	interactor	24	0.707	10.875	CBFNT (PF08143, IPR012956): CBFNT (NUC161) domain RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
117	HNRNPH1	oncoprotein	33	0.564	51.694	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RNPHF (PF08080, IPR012996): RNPHF zinc finger
118	HNRNPH2	interactor	23	0.645	27.500	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RNPHF (PF08080, IPR012996): RNPHF zinc finger
119	HNRNPK	oncoprotein	38	0.470	100.618	ROKNT (PF08067, IPR012987): ROKNT (NUC014) domain KH_1 (PF00013, IPR004088, SM00322): KH domain
120	HNRNPL	protein found in more fusions	24	0.656	18.087	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Dscam_C (PF12355, IPR021012): Down syndrome cell adhesion molecule C terminal RRM_5 (PF13893): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
121	HNRNPLL	protein found in more fusions	5	0.500	1.400	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 (PF11608, IPR024582): Limkain b1 RRM_5 (PF13893): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
122	HNRNPM	interactor	36	0.535	76.143	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HnRNP_M (PF11532, IPR024666): Heterogeneous nuclear ribonucleoprotein M Collagen_mid (PF15984, IPR031929): Bacterial collagen, middle region
123	HNRNPR	interactor	31	0.518	54.363	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 (PF11608, IPR024582): Limkain b1
124	HNRNPU	interactor	65	0.377	433.793	CDC45 (PF02724, IPR003874): CDC45-like protein Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein SAP (PF02037, IPR003034, SM00513): SAP domain SPRY (PF00622, IPR003877, SM00449): SPRY domain AAA_33 (PF13671): AAA domain WRNPLPNID (PF15017): Putative WW-binding domain and destruction box
125	HSP90AA1	oncoprotein	57	0.264	601.792	HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HSP90 (PF00183, IPR001404): Hsp90 protein
126	HSPA1A	interactor	25	0.423	67.141	HSP70 (PF00012, IPR013126): Hsp70 protein
127	HSPA4	interactor	34	0.330	133.261	Herpes_ICP4_N (PF03584, IPR005206): Herpesvirus ICP4-like protein N-terminal region HSP70 (PF00012, IPR013126): Hsp70 protein TP53IP5 (PF15331, IPR029290): Cellular tumour antigen p53-inducible 5
128	HSPA5	oncoprotein	50	0.334	364.687	HSP70 (PF00012, IPR013126): Hsp70 protein
129	HSPA8	oncoprotein	41	0.311	248.308	HSP70 (PF00012, IPR013126): Hsp70 protein
130	IARS	interactor	13	0.385	21.437	Anticodon_1 (PF08264, IPR013155): Anticodon-binding domain of tRNA tRNA-synt_1 (PF00133, IPR002300): tRNA synthetases class I (I, L, M and V)
131	ID1	interactor	3	0.667	0.667	HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
132	ID2	oncoprotein	9	0.464	6.168	HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
133	ID3	oncoprotein	4	0.667	0.250	HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
134	ILF3	oncoprotein	46	0.429	218.330	dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif DZF (PF07528, IPR006561, SM00572): DZF domain
135	IMPDH2	protein found in more fusions	10	0.472	5.367	IMPDH (PF00478, IPR001093): IMP dehydrogenase / GMP reductase domain
136	IREB2	interactor	2	1.000	0	Aconitase (PF00330, IPR001030): Aconitase family (aconitate hydratase) Aconitase_C (PF00694, IPR000573): Aconitase C-terminal domain
137	IVNS1ABP	protein found in more fusions	18	0.507	11.228	BACK (PF07707, IPR011705, SM00875): BTB And C-terminal Kelch BTB (PF00651, IPR013069, SM00225): BTB/POZ domain Kelch_1 (PF01344, IPR006652, SM00612): Kelch motif
138	JADE1	interactor	2	1.000	0	C1_2 (PF03107, IPR004146): C1 domain Glyco_hydro_57 (PF03065, IPR004300): Glycosyl hydrolase family 57 EPL1 (PF10513, IPR019542): Enhancer of polycomb-like eIF-5_eIF-2B (PF01873, IPR002735, SM00653): Domain found in IF2B/IF5 PHD_2 (PF13831): PHD-finger zf-HC5HC2H_2 (PF13832): PHD-zinc-finger like domain
139	JAK2	oncoprotein	10	0.361	16.033	FERM_M (PF00373, IPR019748): FERM central domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain
140	JMJD1C	interactor	2	1.000	0	ArfGap (PF01412, IPR001164, SM00105): Putative GTPase activating protein for Arf JmjC (PF02373, IPR003347, SM00558): JmjC domain, hydroxylase TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit zf-C5HC2 (PF02928, IPR004198): C5HC2 zinc finger RbpA (PF13397, IPR025182): RNA polymerase-binding protein
141	KAT2B	protein found in more fusions	24	0.368	67.732	Acetyltransf_1 (PF00583, IPR000182): Acetyltransferase (GNAT) family PCAF_N (PF06466, IPR009464): PCAF (P300/CBP-associated factor) N-terminal domain Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
142	KAT5	oncoprotein	22	0.333	76.864	MOZ_SAS (PF01853, IPR002717): MOZ/SAS family Tudor-knot (PF11717, IPR025995): RNA binding activity-knot of a chromodomain
143	KIF2C	interactor	6	0.600	0.413	Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family Kinesin (PF00225, IPR001752, SM00129): Kinesin motor domain
144	KIF3A	interactor	4	0.833	0.667	Bacillus_HBL (PF05791, IPR008414): Bacillus haemolytic enterotoxin (HBL) DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664) Vfa1 (PF08432, IPR013640): AAA-ATPase Vps4-associated protein 1 DUF755 (PF05501, IPR008474): Domain of unknown function (DUF755) Fez1 (PF06818): Fez1 Kinesin (PF00225, IPR001752, SM00129): Kinesin motor domain DUF4200 (PF13863, IPR025252): Domain of unknown function (DUF4200)
145	KIF3B	interactor	4	0.833	0.667	DUF948 (PF06103, IPR009293): Bacterial protein of unknown function (DUF948) Kinesin (PF00225, IPR001752, SM00129): Kinesin motor domain WRNPLPNID (PF15017): Putative WW-binding domain and destruction box Kinesin_assoc (PF16183, IPR032405): Kinesin-associated HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1
146	KIFAP3	interactor	6	0.400	9.000	KAP (PF05804): Kinesin-associated protein (KAP)
147	KIRREL2	interactor	2	1.000	0	C2-set_2 (PF08205, IPR013162): CD80-like C2-set immunoglobulin domain I-set (PF07679, IPR013098): Immunoglobulin I-set domain ig (PF00047, IPR013151, SM00409): Immunoglobulin domain SepZ (PF06066, IPR009275): SepZ Ig_3 (PF13927): Immunoglobulin domain
148	KLF4	oncoprotein	11	0.436	10.647	zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
149	KNG1	interactor	1	0	0	Bradykinin (PF06753, IPR009608): Bradykinin Chorion_2 (PF03964, IPR005649): Chorion family 2 Cystatin (PF00031, IPR000010, SM00043): Cystatin domain
150	KNTC1	interactor	3	0.667	1.000	DUF2240 (PF09999, IPR018716): Uncharacterized protein conserved in archaea (DUF2240) MRP-S22 (PF10245, IPR019374): Mitochondrial 28S ribosomal protein S22 Rod_C (PF10493, IPR019527): Rough deal protein C-terminal region
151	LANCL1	interactor	2	1.000	0	LANC_like (PF05147, IPR007822): Lanthionine synthetase C-like protein
152	LIMD1	oncoprotein	7	0.533	5.667	LIM (PF00412, IPR001781, SM00132): LIM domain
153	LPP	oncoprotein	6	0.667	2.944	LIM (PF00412, IPR001781, SM00132): LIM domain zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
154	LTV1	interactor	7	0.619	1.133	DUF1874 (PF08960, IPR015055): Domain of unknown function (DUF1874) LTV (PF04180, IPR007307): Low temperature viability protein
155	MCC	oncoprotein	7	0.333	12.167	ERM (PF00769, IPR011259): Ezrin/radixin/moesin family IFP_35_N (PF07334, IPR009938): Interferon-induced 35 kDa protein (IFP 35) N-terminus K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain Mod_r (PF07200, IPR009851): Modifier of rudimentary (Mod(r)) protein Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein MCC-bdg_PDZ (PF10506, IPR019536): PDZ domain of MCC-2 bdg protein for Usher syndrome TMF_DNA_bd (PF12329, IPR022092): TATA element modulatory factor 1 DNA binding EF-hand_7 (PF13499, IPR011992): EF-hand domain pair FAM76 (PF16046, IPR032017): FAM76 protein
156	MCM7	protein found in more fusions	17	0.400	22.288	MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family MCM_N (PF14551, IPR027925): MCM N-terminal domain MCM_OB (PF17207): MCM OB domain
157	MDFI	interactor	10	0.250	22.341	MDFI (PF15316, IPR026134): MyoD family inhibitor
158	MIF	oncoprotein	12	0.491	14.399	MIF (PF01187, IPR001398): Macrophage migration inhibitory factor (MIF)
159	MKNK2	interactor	7	0.429	7.137	ABC_trans_aux (PF03886, IPR005586): ABC-type transport auxiliary lipoprotein component Pkinase (PF00069, IPR000719): Protein kinase domain
160	MOB4	interactor	11	0.564	20.000	Mob1_phocein (PF03637, IPR005301): Mob1/phocein family
161	MSH4	interactor	2	1.000	0	MutS_II (PF05188, IPR007860): MutS domain II MutS_V (PF00488, IPR000432, SM00534): MutS domain V MutS_III (PF05192, IPR007696, SM00533): MutS domain III
162	MYBBP1A	oncoprotein	22	0.450	51.804	DNA_pol_phi (PF04931, IPR007015): DNA polymerase phi Pol_alpha_B_N (PF08418, IPR013627): DNA polymerase alpha subunit B N-terminal
163	MYC	oncoprotein	65	0.192	825.417	HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain Myc-LZ (PF02344, IPR003327): Myc leucine zipper domain Myc_N (PF01056, IPR012682): Myc amino-terminal region
164	MYL12A	interactor	4	0.667	0.393	EF-hand_11 (PF08976, IPR015070): EF-hand domain DUF2267 (PF10025, IPR018727): Uncharacterized conserved protein (DUF2267) EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
165	NCL	protein found in more fusions	40	0.409	145.777	DUF1754 (PF08555, IPR013865): Eukaryotic family of unknown function (DUF1754) Myc_N (PF01056, IPR012682): Myc amino-terminal region RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) YL1 (PF05764, IPR008895): YL1 nuclear protein Limkain-b1 (PF11608, IPR024582): Limkain b1
166	NEDD8	interactor	47	0.379	189.753	ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
167	NKRF	interactor	5	0.900	0.043	dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif G-patch (PF01585, IPR000467, SM00443): G-patch domain R3H (PF01424, IPR001374, SM00393): R3H domain XTBD (PF11952, IPR021859): XRN-Two Binding Domain, XTBD
168	NOB1	interactor	3	0.667	0.154	NOB1_Zn_bind (PF08772, IPR014881): Nin one binding (NOB1) Zn-ribbon like WRNPLPNID (PF15017): Putative WW-binding domain and destruction box PIN_6 (PF17146): PIN domain of ribonuclease
169	NR4A1	suppressor	11	0.527	8.521	zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
170	OSR1	interactor	2	1.000	0	zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
171	P3H1	interactor	5	0.500	4.067	TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat YfiO (PF13525): Outer membrane lipoprotein 2OG-FeII_Oxy_3 (PF13640, IPR005123): 2OG-Fe(II) oxygenase superfamily MCM_N (PF14551, IPR027925): MCM N-terminal domain Fis1_TPR_C (PF14853, IPR028061): Fis1 C-terminal tetratricopeptide repeat
172	PAPSS2	interactor	3	0.667	0.250	APS_kinase (PF01583, IPR002891): Adenylylsulphate kinase ATP-sulfurylase (PF01747, IPR024951): ATP-sulfurylase DUF258 (PF03193, IPR004881): Protein of unknown function, DUF258 YscJ_FliF (PF01514, IPR006182): Secretory protein of YscJ/FliF family PUA_2 (PF14306, IPR025980): PUA-like domain
173	PARD3	interactor	7	0.429	8.111	PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) DUF3534 (PF12053, IPR021922): Domain of unknown function (DUF3534) PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
174	PARD6A	interactor	6	0.600	4.900	PB1 (PF00564, IPR000270, SM00666): PB1 domain PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
175	PARK7	suppressor	11	0.644	6.598	DJ-1_PfpI (PF01965, IPR002818): DJ-1/PfpI family
176	PARP1	suppressor	27	0.357	72.490	BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain PADR1 (PF08063, IPR012982): PADR1 (NUC008) domain PARP (PF00644, IPR012317): Poly(ADP-ribose) polymerase catalytic domain PARP_reg (PF02877, IPR004102): Poly(ADP-ribose) polymerase, regulatory domain WGR (PF05406, IPR008893, SM00773): WGR domain zf-PARP (PF00645, IPR001510): Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region
177	PCGF2	suppressor	4	0.667	0.143	zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger) RAWUL (PF16207, IPR032443): RAWUL domain RING finger- and WD40-associated ubiquitin-like
178	PCMT1	interactor	10	0.489	8.315	PCMT (PF01135, IPR000682): Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)
179	PDCD5	suppressor	4	0.667	0.255	dsDNA_bind (PF01984, IPR002836): Double-stranded DNA-binding domain EF-1_beta_acid (PF10587, IPR018940): Eukaryotic elongation factor 1 beta central acidic region
180	PFAS	interactor	2	1.000	0	AIRS_C (PF02769, IPR010918): AIR synthase related protein, C-terminal domain GATase_5 (PF13507): CobB/CobQ-like glutamine amidotransferase domain
181	PIAS4	interactor	13	0.372	31.225	CENP-B_dimeris (PF09026, IPR015115): Centromere protein B dimerisation domain SAP (PF02037, IPR003034, SM00513): SAP domain zf-MIZ (PF02891, IPR004181): MIZ/SP-RING zinc finger PINIT (PF14324, IPR023321): PINIT domain
182	PIN1	suppressor	23	0.364	82.703	Rotamase (PF00639, IPR000297): PPIC-type PPIASE domain WW (PF00397, IPR001202, SM00456): WW domain
183	PKD1L3	interactor	1	0	0	GPS (PF01825, IPR000203, SM00303): GPCR proteolysis site, GPS, motif PKD_channel (PF08016, IPR013122): Polycystin cation channel PLAT (PF01477, IPR001024, SM00308): PLAT/LH2 domain Lectin_C (PF00059, IPR001304, SM00034): Lectin C-type domain
184	PLD1	oncoprotein	3	1.000	0	PH (PF00169, IPR001849, SM00233): PH domain PLDc (PF00614, IPR001736, SM00155): Phospholipase D Active site motif PX (PF00787, IPR001683, SM00312): PX domain PLDc_2 (PF13091, IPR025202): PLD-like domain
185	PLD2	interactor	5	0.500	2.872	PH (PF00169, IPR001849, SM00233): PH domain PLDc (PF00614, IPR001736, SM00155): Phospholipase D Active site motif PX (PF00787, IPR001683, SM00312): PX domain PLDc_2 (PF13091, IPR025202): PLD-like domain
186	PLOD2	protein found in more fusions	7	0.533	3.773	2OG-FeII_Oxy (PF03171, IPR005123): 2OG-Fe(II) oxygenase superfamily Anp1 (PF03452, IPR005109): Anp1 Glycos_transf_2 (PF00535, IPR001173): Glycosyl transferase family 2
187	PLOD3	protein found in more fusions	8	0.381	6.258	2OG-FeII_Oxy (PF03171, IPR005123): 2OG-Fe(II) oxygenase superfamily Anp1 (PF03452, IPR005109): Anp1
188	POLR2A	protein found in more fusions	27	0.295	126.536	RNA_pol_Rpb1_1 (PF04997, IPR007080): RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 (PF00623, IPR000722): RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 (PF04983, IPR007066): RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 (PF05000, IPR007083): RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_5 (PF04998, IPR007081): RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_R (PF05001, IPR000684): RNA polymerase Rpb1 C-terminal repeat
189	POLR2G	interactor	4	1.000	0	SHS2_Rpb7-N (PF03876, IPR005576): SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 (PF00575, IPR003029, SM00316): S1 RNA binding domain
190	PPIB	interactor	4	0.833	0.500	Pro_isomerase (PF00160, IPR002130): Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD
191	PPM1B	interactor	4	0.500	2.667	PP2C (PF00481, IPR001932): Protein phosphatase 2C PP2C_C (PF07830, IPR012911, SM00332): Protein serine/threonine phosphatase 2C, C-terminal domain
192	PRDX1	oncoprotein	14	0.526	9.633	AhpC-TSA (PF00578, IPR000866): AhpC/TSA family 1-cysPrx_C (PF10417, IPR019479): C-terminal domain of 1-Cys peroxiredoxin
193	PRKCD	oncoprotein	12	0.527	10.356	Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain)
194	PRKCH	protein found in more fusions	4	1.000	0	C2 (PF00168, IPR000008, SM00239): C2 domain Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain)
195	PRKCI	interactor	8	0.464	10.151	PB1 (PF00564, IPR000270, SM00666): PB1 domain Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain)
196	PRKCZ	interactor	12	0.327	27.908	PB1 (PF00564, IPR000270, SM00666): PB1 domain Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain)
197	PRMT1	interactor	19	0.490	25.197	Methyltransf_25 (PF13649): Methyltransferase domain
198	PRMT3	interactor	7	0.524	3.054	PrmA (PF06325, IPR010456): Ribosomal protein L11 methyltransferase (PrmA) zf-C2H2_2 (PF12756, IPR015880): C2H2 type zinc-finger (2 copies)
199	PRMT8	interactor	6	1.000	0	PrmA (PF06325, IPR010456): Ribosomal protein L11 methyltransferase (PrmA)
200	PSMB1	interactor	15	0.438	27.853	Proteasome (PF00227, IPR001353): Proteasome subunit
201	PSMB3	protein found in more fusions	9	0.714	2.416	Proteasome (PF00227, IPR001353): Proteasome subunit
202	PSMC3	interactor	14	0.436	22.918	AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA) DUF3713 (PF12506, IPR022186): Protein of unknown function (DUF3713) JIP_LZII (PF16471, IPR032486): JNK-interacting protein leucine zipper II
203	PSMD13	interactor	8	0.643	4.169	Mitovir_RNA_pol (PF05919, IPR008686): Mitovirus RNA-dependent RNA polymerase PCI (PF01399, IPR000717, SM00088): PCI domain
204	PTPN14	oncoprotein	4	0.667	0.157	FERM_C (PF09380, IPR018980): FERM C-terminal PH-like domain FERM_M (PF00373, IPR019748): FERM central domain FERM_N (PF09379, IPR018979): FERM N-terminal domain Y_phosphatase (PF00102, IPR000242, SM00194): Protein-tyrosine phosphatase
205	RAB1B	oncoprotein	3	0.667	0.333	Ras (PF00071, IPR001806, SM00173): Ras family
206	RACK1	oncoprotein	33	0.440	123.804	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
207	RALYL	protein found in more fusions	3	1.000	0	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TFIIIC_sub6 (PF10419, IPR019481): TFIIIC subunit CENP-Q (PF13094, IPR025212): CENP-Q, a CENPA-CAD centromere complex subunit
208	RASGRP1	oncoprotein	3	0.667	1.000	bZIP_1 (PF00170, IPR004827): bZIP transcription factor FlaC_arch (PF05377, IPR008039): Flagella accessory protein C (FlaC) RasGEF (PF00617, IPR001895, SM00147): RasGEF domain C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain) EF-hand_1 (PF00036, IPR002048, SM00054): EF hand RasGEF_N (PF00618, IPR000651, SM00229): RasGEF N-terminal motif EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
209	RB1CC1	oncoprotein	5	0.600	2.139	Arc_PepC_II (PF06847, IPR009655): Archaeal Peptidase A24 C-terminus Type II DHC (PF09626, IPR018588): Dihaem cytochrome c DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972) FlaC_arch (PF05377, IPR008039): Flagella accessory protein C (FlaC) ATG11 (PF10377, IPR019460): Autophagy-related protein 11 DUF4407 (PF14362, IPR025519): Domain of unknown function (DUF4407) Jag_N (PF14804, IPR032782): Jag N-terminus NPBW (PF15180, IPR013297): Neuropeptides B and W HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1 BST2 (PF16716, IPR024886): Bone marrow stromal antigen 2 Goodbye (PF17109, IPR031350): fungal STAND N-terminal Goodbye domain
210	RBBP4	oncoprotein	18	0.379	43.223	eIF2A (PF08662, IPR013979): Eukaryotic translation initiation factor eIF2A WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Capsid_NCLDV (PF04451, IPR007542): Large eukaryotic DNA virus major capsid protein CAF1C_H4-bd (PF12265, IPR022052): Histone-binding protein RBBP4 or subunit C of CAF1 complex
211	RBBP7	oncoprotein	11	0.564	13.088	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Capsid_NCLDV (PF04451, IPR007542): Large eukaryotic DNA virus major capsid protein CAF1C_H4-bd (PF12265, IPR022052): Histone-binding protein RBBP4 or subunit C of CAF1 complex
212	RBPMS	protein found in more fusions	8	0.286	11.056	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
213	RBPMS2	interactor	1	0	0	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
214	RBX1	oncoprotein	23	0.416	56.997	zf-rbx1 (PF12678, IPR024766): RING-H2 zinc finger domain
215	RHOBTB3	protein found in more fusions	8	0.476	7.721	BTB (PF00651, IPR013069, SM00225): BTB/POZ domain Ras (PF00071, IPR001806, SM00173): Ras family
216	RHOC	oncoprotein	2	1.000	0	Ras (PF00071, IPR001806, SM00173): Ras family
217	RIT1	interactor	1	0	0	Ras (PF00071, IPR001806, SM00173): Ras family
218	RNF7	oncoprotein	12	0.473	13.037	zf-rbx1 (PF12678, IPR024766): RING-H2 zinc finger domain Prok-RING_1 (PF14446): Prokaryotic RING finger family 1
219	RPA3	interactor	42	0.288	179.989	Rep_fac-A_3 (PF08661, IPR013970): Replication factor A protein 3
220	RPL10A	interactor	34	0.747	27.010	Ribosomal_L1 (PF00687, IPR028364): Ribosomal protein L1p/L10e family
221	RPL11	suppressor	38	0.697	31.456	Ribosomal_L5 (PF00281, IPR002132): Ribosomal protein L5 Ribosomal_L5_C (PF00673, IPR002132): ribosomal L5P family C-terminus
222	RPL12	interactor	38	0.700	54.181	Ribosomal_L11 (PF00298, IPR020783): Ribosomal protein L11, RNA binding domain Ribosomal_L11_N (PF03946, IPR020784): Ribosomal protein L11, N-terminal domain
223	RPL14	interactor	34	0.761	19.959	KOW (PF00467, IPR005824, SM00739): KOW motif Ribosomal_L14e (PF01929, IPR002784): Ribosomal protein L14 UPF0688 (PF15772, IPR031530): UPF0688 family
224	RPL18A	interactor	30	0.814	10.286	Ribosomal_L18A (PF01775, IPR023573): Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A
225	RPL21	interactor	34	0.777	27.810	Ribosomal_L21e (PF01157, IPR001147): Ribosomal protein L21e
226	RPL30	interactor	30	0.807	20.479	NCBP3 (PF10309, IPR019416): Nuclear cap-binding protein subunit 3
227	RPL5	oncoprotein	44	0.574	125.929	Ribosomal_L18_c (PF14204, IPR025607): Ribosomal L18 C-terminal region Ribosomal_L5e (PF17144): Ribosomal large subunit proteins 60S L5, and 50S L18
228	RPL7A	interactor	34	0.677	68.738	Ribosomal_L7Ae (PF01248, IPR004038): Ribosomal protein L7Ae/L30e/S12e/Gadd45 family
229	RPLP0	interactor	43	0.591	78.134	Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein Ribosomal_L10 (PF00466, IPR001790): Ribosomal protein L10
230	RPS11	interactor	34	0.724	23.780	Ribosomal_S17 (PF00366, IPR000266): Ribosomal protein S17 Ribosomal_S17_N (PF16205, IPR032440): Ribosomal_S17 N-terminal
231	RPS14	interactor	34	0.781	14.173	Ribosomal_S11 (PF00411, IPR001971): Ribosomal protein S11
232	RPS15A	interactor	36	0.706	33.194	Ribosomal_S8 (PF00410, IPR000630): Ribosomal protein S8
233	RPS17	interactor	21	0.905	1.348	Ribosomal_S17e (PF00833, IPR001210): Ribosomal S17
234	RPS2	interactor	44	0.564	142.957	Ribosomal_S5 (PF00333, IPR013810): Ribosomal protein S5, N-terminal domain Ribosomal_S5_C (PF03719, IPR005324): Ribosomal protein S5, C-terminal domain
235	RPS27	interactor	30	0.848	6.648	Ribosomal_S27e (PF01667, IPR000592): Ribosomal protein S27 DUF3795 (PF12675, IPR024227): Protein of unknown function (DUF3795)
236	RPS27L	interactor	20	0.774	10.494	E7 (PF00527, IPR000148): E7 protein, Early protein Ribosomal_S27e (PF01667, IPR000592): Ribosomal protein S27 zf-C2HC5 (PF06221, IPR009349): Putative zinc finger motif, C2HC5-type DUF3382 (PF11862, IPR021807): Domain of unknown function (DUF3382)
237	RPS3	interactor	45	0.579	106.594	KH_2 (PF07650, IPR004044): KH domain Ribosomal_S3_C (PF00189, IPR001351): Ribosomal protein S3, C-terminal domain
238	RPS3A	interactor	41	0.668	40.722	Ribosomal_S3Ae (PF01015, IPR001593): Ribosomal S3Ae family
239	RPS5	interactor	33	0.708	26.098	Ribosomal_S7 (PF00177, IPR023798): Ribosomal protein S7p/S5e
240	RPS6	interactor	39	0.692	39.164	Ribosomal_S6e (PF01092, IPR001377): Ribosomal protein S6e DUF4574 (PF15141, IPR027896): Domain of unknown function (DUF4574)
241	RPS9	interactor	34	0.758	17.940	Ribosomal_S4 (PF00163, IPR001912): Ribosomal protein S4/S9 N-terminal domain S4 (PF01479, IPR002942, SM00363): S4 domain
242	RPSA	interactor	39	0.568	97.144	Ribosomal_S2 (PF00318, IPR001865): Ribosomal protein S2 40S_SA_C (PF16122, IPR032281): 40S ribosomal protein SA C-terminus
243	RWDD3	interactor	2	1.000	0	DUF1115 (PF06544, IPR010541): Protein of unknown function (DUF1115) RWD (PF05773, IPR006575, SM00591): RWD domain
244	SAP130	interactor	8	0.536	4.672	SAP130_C (PF16014, IPR031963): Histone deacetylase complex subunit SAP130 C-terminus
245	SARNP	oncoprotein	4	0.500	1.368	SAP (PF02037, IPR003034, SM00513): SAP domain HTH_Tnp_IS630 (PF01710, IPR002622): Transposase Prok-E2_A (PF14457, IPR032865): Prokaryotic E2 family A
246	SAT2	interactor	5	0.833	0.667	Acetyltransf_1 (PF00583, IPR000182): Acetyltransferase (GNAT) family
247	SIRT1	oncoprotein	25	0.326	98.274	DUF592 (PF04574, IPR007654): Protein of unknown function (DUF592) SIR2 (PF02146, IPR003000): Sir2 family TPP_enzyme_M (PF00205, IPR012000): Thiamine pyrophosphate enzyme, central domain
248	SKP2	oncoprotein	21	0.343	63.840	LRR_1 (PF00560, IPR001611): Leucine Rich Repeat LRR_2 (PF07723, IPR013101): Leucine Rich Repeat LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies) F-box-like (PF12937, IPR001810): F-box-like LRR_6 (PF13516, IPR001611): Leucine Rich repeat LRR_8 (PF13855, IPR001611): Leucine rich repeat
249	SLC2A1	interactor	2	1.000	0	Sugar_tr (PF00083, IPR005828): Sugar (and other) transporter
250	SLC3A2	interactor	5	0.600	2.500	Alpha-amylase (PF00128, IPR006047): Alpha amylase, catalytic domain DUF3459 (PF11941, IPR022567): Domain of unknown function (DUF3459) SLC3A2_N (PF16028, IPR031984): Solute carrier family 3 member 2 N-terminus
251	SNRNP70	interactor	19	0.596	14.042	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MIP-T3 (PF10243): Microtubule-binding protein MIP-T3 U1snRNP70_N (PF12220, IPR022023): U1 small nuclear ribonucleoprotein of 70kDa MW N terminal
252	SOCS1	oncoprotein	7	0.476	6.352	SH2 (PF00017, IPR000980, SM00252): SH2 domain SOCS_box (PF07525, IPR001496): SOCS box
253	SOCS3	suppressor	11	0.364	17.730	SH2 (PF00017, IPR000980, SM00252): SH2 domain SOCS_box (PF07525, IPR001496): SOCS box
254	SON	interactor	5	0.400	3.321	Asp-B-Hydro_N (PF05279, IPR007943): Aspartyl beta-hydroxylase N-terminal region G-patch (PF01585, IPR000467, SM00443): G-patch domain tRNA_synt_1c_R2 (PF04557, IPR007638): Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 Eapp_C (PF10238, IPR019370): E2F-associated phosphoprotein DND1_DSRM (PF14709): double strand RNA binding domain from DEAD END PROTEIN 1 GREB1 (PF15782, IPR028422): Gene regulated by oestrogen in breast cancer RSRP (PF17069): Arginine/Serine-Rich protein 1
255	SP1	protein found in more fusions	29	0.339	117.106	zf-Di19 (PF05605, IPR008598): Drought induced 19 protein (Di19), zinc-binding Herpes_capsid (PF06112, IPR009299): Gammaherpesvirus capsid protein zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type Miga (PF10265, IPR019392): Mitoguardin zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
256	SPRY2	suppressor	10	0.250	25.000	KAR9 (PF08580, IPR013889): Yeast cortical protein KAR9 Sprouty (PF05210, IPR007875): Sprouty protein (Spry)
257	STK16	interactor	5	0.500	3.000	Pkinase (PF00069, IPR000719): Protein kinase domain
258	STK38	interactor	4	0.667	0.286	MEKHLA (PF08670, IPR013978): MEKHLA domain Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
259	STUB1	suppressor	24	0.332	76.618	U-box (PF04564, IPR003613, SM00504): U-box domain ANAPC3 (PF12895): Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 (PF13414, IPR011990): TPR repeat TPR_20 (PF14561): Tetratricopeptide repeat
260	TAGLN2	interactor	10	0.422	10.050	Calponin (PF00402, IPR000557): Calponin family repeat CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
261	TARDBP	interactor	53	0.397	217.880	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
262	TARS	interactor	9	0.389	12.296	HGTP_anticodon (PF03129, IPR004154): Anticodon binding domain TGS (PF02824, IPR004095): TGS domain tRNA-synt_2b (PF00587, IPR002314): tRNA synthetase class II core domain (G, H, P, S and T) tRNA_SAD (PF07973, IPR012947, SM00863): Threonyl and Alanyl tRNA synthetase second additional domain
263	TCEB1	interactor	27	0.262	166.689	Skp1_POZ (PF03931, IPR016073): Skp1 family, tetramerisation domain
264	TCEB2	interactor	22	0.338	81.501	ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
265	TCEB3	suppressor	7	0.476	8.900	Elongin_A (PF06881, IPR010684): RNA polymerase II transcription factor SIII (Elongin) subunit A Med26 (PF08711, IPR017923): TFIIS helical bundle-like domain
266	TCP1	interactor	22	0.615	22.846	Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
267	TGFB1I1	interactor	2	1.000	0	LIM (PF00412, IPR001781, SM00132): LIM domain Paxillin (PF03535): Paxillin family
268	TGM2	protein found in more fusions	12	0.345	25.419	Transglut_C (PF00927, IPR008958): Transglutaminase family, C-terminal ig like domain Transglut_N (PF00868, IPR001102): Transglutaminase family Transglut_core (PF01841, IPR002931, SM00460): Transglutaminase-like superfamily
269	TOP2A	oncoprotein	17	0.426	23.808	DNA_gyraseB (PF00204, IPR013506): DNA gyrase B DTHCT (PF08070, IPR012542): DTHCT (NUC029) region HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Sec62 (PF03839, IPR004728): Translocation protein Sec62 Toprim (PF01751, IPR006171, SM00493): Toprim domain DNA_topoisoIV (PF00521, IPR002205, SM00434): DNA gyrase/topoisomerase IV, subunit A PHC2_SAM_assoc (PF16616): Unstructured region on Polyhomeotic-like protein 1 and 2 TOPRIM_C (PF16898, IPR031660): C-terminal associated domain of TOPRIM
270	TP53	oncoprotein	101	0.173	2140.709	DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region P53 (PF00870, IPR011615): P53 DNA-binding domain P53_tetramer (PF07710, IPR010991): P53 tetramerisation motif
271	TPT1	interactor	4	0.667	0.183	TCTP (PF00838, IPR018105): Translationally controlled tumour protein
272	TRAFD1	interactor	3	1.000	0	zf-Di19 (PF05605, IPR008598): Drought induced 19 protein (Di19), zinc-binding DM (PF00751, IPR001275, SM00301): DM DNA binding domain zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-C2H2_4 (PF13894): C2H2-type zinc finger zf-C2HC_2 (PF13913): zinc-finger of a C2HC-type
273	TRIM28	protein found in more fusions	36	0.277	232.137	ASFV_J13L (PF05568, IPR008385): African swine fever virus J13L protein K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain PHD (PF00628, IPR019787, SM00249): PHD-finger FYVE_2 (PF02318, IPR010911): FYVE-type zinc finger zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger zf-RING_5 (PF14634, IPR001841): zinc-RING finger domain SKA2 (PF16740, IPR026762): Spindle and kinetochore-associated protein 2
274	TRIP12	interactor	6	0.533	1.752	Alpha_GJ (PF03229, IPR004913): Alphavirus glycoprotein J Ndc1_Nup (PF09531, IPR019049): Nucleoporin protein Ndc1-Nup WWE (PF02825, IPR004170, SM00678): WWE domain SOG2 (PF10428, IPR019487): RAM signalling pathway protein HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase) UNC45-central (PF11701, IPR024660): Myosin-binding striated muscle assembly central HEAT_2 (PF13646): HEAT repeats
275	TUBA1A	oncoprotein	12	0.515	11.149	Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain
276	TUBA3C	interactor	5	0.700	0.887	Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain
277	TUBA3D	interactor	4	0.500	0.476	Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain
278	TUBA3E	interactor	5	0.700	2.000	Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain
279	TUBA4A	interactor	15	0.638	6.698	Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain
280	TUBB4B	interactor	21	0.376	47.400	Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain
281	TXN	oncoprotein	11	0.545	8.258	Thioredoxin (PF00085, IPR013766): Thioredoxin
282	UBC	protein found in more fusions	68	0.178	1088.932	ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
283	UBE2D1	interactor	16	0.400	30.379	UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
284	UBE2D2	oncoprotein	13	0.409	20.660	UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
285	UBR5	protein found in more fusions	8	0.667	3.219	CENP-B_dimeris (PF09026, IPR015115): Centromere protein B dimerisation domain SDA1 (PF05285, IPR007949): SDA1 HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase) PABP (PF00658, IPR002004, SM00517): Poly-adenylate binding protein, unique domain E3_UbLigase_EDD (PF11547, IPR024725): E3 ubiquitin ligase EDD PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term DUF3915 (PF13054, IPR025026): Protein of unknown function (DUF3915) RCDG1 (PF15725, IPR031457): Renal cancer differentiation gene 1 protein
286	UBXN7	interactor	13	0.526	17.545	UBX (PF00789, IPR001012, SM00166): UBX domain UIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif Thioredoxin_7 (PF13899): Thioredoxin-like UBA_4 (PF14555): UBA-like domain
287	USP20	protein found in more fusions	9	0.357	15.633	UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase zf-UBP (PF02148, IPR001607, SM00290): Zn-finger in ubiquitin-hydrolases and other protein DUSP (PF06337, IPR006615, SM00695): DUSP domain
288	USP33	suppressor	9	0.417	9.568	UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase zf-UBP (PF02148, IPR001607, SM00290): Zn-finger in ubiquitin-hydrolases and other protein DUSP (PF06337, IPR006615, SM00695): DUSP domain
289	UXT	interactor	3	0.667	0.400	Prefoldin (PF02996, IPR004127): Prefoldin subunit
290	VAPB	interactor	6	0.600	4.233	ATP-synt_G (PF04718, IPR006808): Mitochondrial ATP synthase g subunit ZapB (PF06005, IPR009252): Cell division protein ZapB Motile_Sperm (PF00635, IPR000535): MSP (Major sperm protein) domain
291	VBP1	interactor	8	0.250	16.319	Prefoldin (PF02996, IPR004127): Prefoldin subunit
292	WTIP	interactor	1	0	0	DUF983 (PF06170, IPR009325): Protein of unknown function (DUF983) LIM (PF00412, IPR001781, SM00132): LIM domain
293	XRCC5	suppressor	20	0.415	27.274	Ku (PF02735, IPR006164, SM00559): Ku70/Ku80 beta-barrel domain Ku_C (PF03730, IPR005160): Ku70/Ku80 C-terminal arm Ku_N (PF03731, IPR005161): Ku70/Ku80 N-terminal alpha/beta domain Ku_PK_bind (PF08785, IPR014893): Ku C terminal domain like
294	YY1AP1	interactor	1	0	0	CtnDOT_TraJ (PF07863, IPR012424): Homologues of TraJ from Bacteroides conjugative transposon JAKMIP_CC3 (PF16034, IPR031994): JAKMIP CC3 domain
295	ZNF197	interactor	3	1.000	0	KRAB (PF01352, IPR001909, SM00349): KRAB box SCAN (PF02023, IPR003309, SM00431): SCAN domain zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_4 (PF13894): C2H2-type zinc finger
296	ZNF350	interactor	3	0.667	0.143	KRAB (PF01352, IPR001909, SM00349): KRAB box zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
297	ZNF512B	interactor	6	0.533	3.117	YTV (PF07639, IPR011521): YTV zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-C2HC5 (PF06221, IPR009349): Putative zinc finger motif, C2HC5-type zf-Nse (PF11789, IPR004181): Zinc-finger of the MIZ type in Nse subunit Zn_Tnp_IS1595 (PF12760, IPR024442): Transposase zinc-ribbon domain zf-C2H2_4 (PF13894): C2H2-type zinc finger zf-C2H2_aberr (PF17017, IPR031514): Aberrant zinc-finger
298	ZYX	suppressor	7	0.429	7.242	DUF1180 (PF06679, IPR009565): Protein of unknown function (DUF1180) LIM (PF00412, IPR001781, SM00132): LIM domain DUF2757 (PF10955, IPR020115): Protein of unknown function (DUF2757)

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