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Visible interactions: all affected independent (normal) missing (in fusions) nothing (blank)

Visualization interactions

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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)51
The number (and %) of the onco-proteins16 (31.37 %)
The number (and %) of the tumor suppressors9 (17.65 %)
Total number of binary PPIs (saturation %)216 (16.94 %)
The number (and %) of affected PPIs51 (23.61 %)
The number of possible different fusions12
PPI diameter2
PPI radius1
The average degree of PPI7.451
Assortativity coefficient-0.2159
The network average Clustering coefficient0.641
The number (and %) of a zero Clustering coefficients4 (7.84 %)
The number (and %) of a zero Betweenness Centrality17 (33.33 %)

ACTIVE INTERACTORS
MISSING INTERACTORS (in fusions)


List of the fusions

PPI for parental proteins: USP10 All fusions
: BE091809;
Proteins found in more fusions TRAF6 (see 1 fusions); PABPC1 (see 2 fusions); PCNA (see 1 fusions); UBC (see 1 fusions); G3BP1 (see 1 fusions); VCP (see 4 fusions); ULK1 (see 2 fusions); TP53 (see 3 fusions); IBTK (see 2 fusions); USP10 (see 1 fusions); NPM1 (see 1 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 USP10parental protein510.1141619.423PAM2 (PF07145, IPR009818): Ataxin-2 C-terminal region
UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase
YukD (PF08817, IPR024962): WXG100 protein secretion system (Wss), protein YukD
2 ANKRD28interactor41.0000Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
Ank_4 (PF13637): Ankyrin repeats (many copies)
Ank_5 (PF13857): Ankyrin repeats (many copies)
3 ARoncoprotein70.7331.967Androgen_recep (PF02166, IPR001103): Androgen receptor
zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains)
Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
4 CDC5Linteractor70.6672.833OmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like)
Pox_A_type_inc (PF04508, IPR007596): Viral A-type inclusion protein repeat
Cir_N (PF10197, IPR019339, SM01083): N-terminal domain of CBF1 interacting co-repressor CIR
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
Myb_Cef (PF11831, IPR021786): pre-mRNA splicing factor component
Myb_DNA-bind_6 (PF13921): Myb-like DNA-binding domain
5 CELF1interactor21.0000RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
6 CFTRsuppressor41.0000ABC_membrane (PF00664, IPR001140): ABC transporter transmembrane region
ABC_tran (PF00005, IPR003439): ABC transporter
Roc (PF08477, IPR013684): Ras of Complex, Roc, domain of DAPkinase
SMC_N (PF02463, IPR003395): RecF/RecN/SMC N terminal domain
Rotamase_2 (PF13145, IPR000297): PPIC-type PPIASE domain
CFTR_R (PF14396, IPR025837): Cystic fibrosis TM conductance regulator (CFTR), regulator domain
7 EIF4G1oncoprotein70.7622.733DUF1180 (PF06679, IPR009565): Protein of unknown function (DUF1180)
MA3 (PF02847, IPR003891, SM00544): MA3 domain
MIF4G (PF02854, IPR003890, SM00543): MIF4G domain
Neisseria_TspB (PF05616, IPR008708): Neisseria meningitidis TspB protein
W2 (PF02020, IPR003307, SM00515): eIF4-gamma/eIF5/eIF2-epsilon
8 EIF4G3interactor51.0000MA3 (PF02847, IPR003891, SM00544): MA3 domain
MIF4G (PF02854, IPR003890, SM00543): MIF4G domain
W2 (PF02020, IPR003307, SM00515): eIF4-gamma/eIF5/eIF2-epsilon
9 G3BP1protein found in more fusions160.42940.535NTF2 (PF02136, IPR002075): Nuclear transport factor 2 (NTF2) domain
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
DUF3306 (PF11748, IPR021735): Protein of unknown function (DUF3306)
PTPRCAP (PF15713, IPR016553): Protein tyrosine phosphatase receptor type C-associated
10 G3BP2interactor110.6189.996NTF2 (PF02136, IPR002075): Nuclear transport factor 2 (NTF2) domain
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
11 GAR1interactor100Gar1 (PF04410, IPR007504): Gar1/Naf1 RNA binding region
12 HECW2interactor31.0000C2 (PF00168, IPR000008, SM00239): C2 domain
WW (PF00397, IPR001202, SM00456): WW domain
HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
Cep57_CLD (PF14073, IPR025913): Centrosome localisation domain of Cep57
RFXA_RFXANK_bdg (PF15289, IPR029316): Regulatory factor X-associated C-terminal binding domain
HECW_N (PF16562, IPR032348): N-terminal domain of E3 ubiquitin-protein ligase HECW1 and 2
13 IBTKprotein found in more fusions50.8330.286BTB (PF00651, IPR013069, SM00225): BTB/POZ domain
RCC1 (PF00415, IPR000408): Regulator of chromosome condensation (RCC1) repeat
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
RCC1_2 (PF13540): Regulator of chromosome condensation (RCC1) repeat
Ank_5 (PF13857): Ankyrin repeats (many copies)
14 IKBKGinteractor60.9000.500CENP-H (PF05837, IPR008426): Centromere protein H (CENP-H)
DUF725 (PF05267, IPR007931): Protein of unknown function (DUF725)
NEMO (PF11577, IPR021063): NF-kappa-B essential modulator NEMO
LLC1 (PF14945, IPR020339): Normal lung function maintenance, Low in Lung Cancer 1 protein
CC2-LZ (PF16516, IPR032419): Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator
15 KLHDC3interactor100Kelch_2 (PF07646, IPR011498): Kelch motif
Kelch_3 (PF13415): Galactose oxidase, central domain
Kelch_4 (PF13418): Galactose oxidase, central domain
Kelch_5 (PF13854): Kelch motif
Kelch_6 (PF13964): Kelch motif
16 KMT2Einteractor30.6670.400CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
PHD (PF00628, IPR019787, SM00249): PHD-finger
SET (PF00856, IPR001214, SM00317): SET domain
MSA-2c (PF12238, IPR021060): Merozoite surface antigen 2c
DUF4124 (PF13511, IPR025392): Domain of unknown function (DUF4124)
PHD_3 (PF13922, IPR026905): PHD domain of transcriptional enhancer, Asx
DUF4666 (PF15697, IPR031421): Domain of unknown function (DUF4666)
PRIMA1 (PF16101): Proline-rich membrane anchor 1
17 MDM2oncoprotein120.45519.089Pinin_SDK_N (PF04697, IPR006787): pinin/SDK conserved region
Presenilin (PF01080, IPR001108): Presenilin
SWIB (PF02201, IPR003121, SM00151): SWIB/MDM2 domain
zf-FPG_IleRS (PF06827, IPR010663): Zinc finger found in FPG and IleRS
zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others
zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
18 NOP56interactor70.6193.824Cytochrom_NNT (PF03264, IPR005126): NapC/NirT cytochrome c family, N-terminal region
Nop (PF01798, IPR002687): snoRNA binding domain, fibrillarin
NOP5NT (PF08156, IPR012974): NOP5NT (NUC127) domain
RNA_polI_A34 (PF08208, IPR013240): DNA-directed RNA polymerase I subunit RPA34.5
SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal
19 NPM1suppressor140.51318.067Nucleoplasmin (PF03066): Nucleoplasmin
SDA1 (PF05285, IPR007949): SDA1
NPM1-C (PF16276, IPR032569): Nucleophosmin C-terminal domain
20 NTRK1oncoprotein240.285138.282I-set (PF07679, IPR013098): Immunoglobulin I-set domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
LRR_8 (PF13855, IPR001611): Leucine rich repeat
TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain
21 PABPC1oncoprotein100.7224.822RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
PABP (PF00658, IPR002004, SM00517): Poly-adenylate binding protein, unique domain
YflT (PF11181, IPR025889): Heat induced stress protein YflT
22 PCNAoncoprotein70.6003.241PCNA_C (PF02747, IPR022649): Proliferating cell nuclear antigen, C-terminal domain
PCNA_N (PF00705, IPR022648): Proliferating cell nuclear antigen, N-terminal domain
23 PPP6R1interactor50.8001.333CENP-B_dimeris (PF09026, IPR015115): Centromere protein B dimerisation domain
SAPS (PF04499, IPR007587): SIT4 phosphatase-associated protein
WRNPLPNID (PF15017): Putative WW-binding domain and destruction box
24 PPP6R3interactor41.0000SAPS (PF04499, IPR007587): SIT4 phosphatase-associated protein
25 PRKAA1suppressor70.5716.750Pkinase (PF00069, IPR000719): Protein kinase domain
AdenylateSensor (PF16579, IPR032270): Adenylate sensor of SNF1-like protein kinase
26 PRKAA2suppressor41.0000Pkinase (PF00069, IPR000719): Protein kinase domain
AdenylateSensor (PF16579, IPR032270): Adenylate sensor of SNF1-like protein kinase
27 PTENsuppressor50.8000.800DSPc (PF00782, IPR020422, SM00195): Dual specificity phosphatase, catalytic domain
PTEN_C2 (PF10409, IPR014020): C2 domain of PTEN tumour-suppressor protein
28 RAD51interactor41.0000Rad51 (PF08423, IPR013632): Rad51
HHH_5 (PF14520): Helix-hairpin-helix domain
29 RPL10suppressor100.57811.056Ribosomal_L16 (PF00252, IPR016180): Ribosomal protein L16p/L10e
30 SCNN1Ainteractor21.0000ASC (PF00858, IPR001873): Amiloride-sensitive sodium channel
31 SF3B3interactor70.5246.686CPSF_A (PF03178, IPR004871): CPSF A subunit region
MMS1_N (PF10433): Mono-functional DNA-alkylating methyl methanesulfonate N-term
32 SIRT6suppressor50.6001.833SIR2 (PF02146, IPR003000): Sir2 family
TPP_enzyme_M (PF00205, IPR012000): Thiamine pyrophosphate enzyme, central domain
33 SNX3interactor30.6671.000PX (PF00787, IPR001683, SM00312): PX domain
34 TANKsuppressor51.0000DUF3713 (PF12506, IPR022186): Protein of unknown function (DUF3713)
TBD (PF12845, IPR024581): TBD domain
35 TARDBPinteractor140.47427.572RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
36 TBPinteractor51.0000TBP (PF00352, IPR000814): Transcription factor TFIID (or TATA-binding protein, TBP)
EPL1 (PF10513, IPR019542): Enhancer of polycomb-like
Med3 (PF11593, IPR020998): Mediator complex subunit 3 fungal
37 TBX21oncoprotein21.0000T-box (PF00907, IPR001699, SM00425): T-box
T-box_assoc (PF16176, IPR032385): T-box transcription factor-associated
38 TP53suppressor170.34260.525DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region
P53 (PF00870, IPR011615): P53 DNA-binding domain
P53_tetramer (PF07710, IPR010991): P53 tetramerisation motif
39 TRAF6protein found in more fusions120.38226.471SlyX (PF04102, IPR007236): SlyX
zf-TRAF (PF02176, IPR001293): TRAF-type zinc finger
zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
40 TRPM8interactor21.0000Ion_trans (PF00520, IPR005821): Ion transport protein
41 TSKSinteractor100TSKS (PF15358, IPR028214): Testis-specific serine kinase substrate
42 UBCprotein found in more fusions190.31482.033ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
43 UBE2Sinteractor70.5334.119ALF (PF03752, IPR005506): Short repeats of unknown function
UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
44 ULK1protein found in more fusions60.7001.900Pkinase (PF00069, IPR000719): Protein kinase domain
DUF3543 (PF12063, IPR022708): Domain of unknown function (DUF3543)
RCDG1 (PF15725, IPR031457): Renal cancer differentiation gene 1 protein
45 USP15oncoprotein80.6193.667UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase
DUSP (PF06337, IPR006615, SM00695): DUSP domain
Ubiquitin_3 (PF14836, IPR028135): Ubiquitin-like domain
46 VCPprotein found in more fusions160.35249.883AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA)
CDC48_2 (PF02933, IPR004201, SM01072): Cell division protein 48 (CDC48), domain 2
CDC48_N (PF02359, IPR003338, SM01073): Cell division protein 48 (CDC48), N-terminal domain
TniB (PF05621, IPR008868): Bacterial TniB protein
Vps4_C (PF09336, IPR015415): Vps4 C terminal oligomerisation domain
DUF3944 (PF13099, IPR025217): Domain of unknown function (DUF3944)
47 WAPLinteractor70.5333.286WAPL (PF07814, IPR022771): Wings apart-like protein regulation of heterochromatin
GAS (PF13851, IPR025593): Growth-arrest specific micro-tubule binding
48 YBX1oncoprotein90.5009.589CSD (PF00313, IPR002059): 'Cold-shock' DNA-binding domain
PBP1_TM (PF14812, IPR032730): Transmembrane domain of transglycosylase PBP1 at N-terminal
FXR_C1 (PF16096, IPR032172): Fragile X-related 1 protein C-terminal region 2
49 ZC3H12Ainteractor60.9000.500RNase_Zc3h12a (PF11977, IPR021869): Zc3h12a-like Ribonuclease NYN domain
zf-CCCH_2 (PF14608): RNA-binding, Nab2-type zinc finger
50 ZC3H18interactor60.6005.000FSAP_sig_propep (PF03032, IPR004275): Frog skin active peptide family signal and propeptide
Vfa1 (PF08432, IPR013640): AAA-ATPase Vps4-associated protein 1
DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777)
Peptidase_S49_N (PF08496, IPR013703): Peptidase family S49 N-terminal
Miga (PF10265, IPR019392): Mitoguardin
DUF3729 (PF12526, IPR022202): Protein of unknown function (DUF3729)
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
PBP1_TM (PF14812, IPR032730): Transmembrane domain of transglycosylase PBP1 at N-terminal
LRR19-TM (PF15176): Leucine-rich repeat family 19 TM domain
51 ZNF281oncoprotein100CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
FYVE (PF01363, IPR000306, SM00064): FYVE zinc finger
GRP (PF07172, IPR010800): Glycine rich protein family
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
RhlB (PF12300, IPR022077): ATP-dependent RNA helicase RhlB
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
zf-C2H2_4 (PF13894): C2H2-type zinc finger

B a c k    t o    T o p ⇑


List of missing interactors (in fusions)

# Name Type Domains (Pfam, InterPro, SMART): description Fusion(s)
1 ANKRD28interactorAnk_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
Ank_4 (PF13637): Ankyrin repeats (many copies)
Ank_5 (PF13857): Ankyrin repeats (many copies)
BE091809
2 ARoncoproteinAndrogen_recep (PF02166, IPR001103): Androgen receptor
zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains)
Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
BE091809
3 CDC5LinteractorOmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like)
Pox_A_type_inc (PF04508, IPR007596): Viral A-type inclusion protein repeat
Cir_N (PF10197, IPR019339, SM01083): N-terminal domain of CBF1 interacting co-repressor CIR
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
Myb_Cef (PF11831, IPR021786): pre-mRNA splicing factor component
Myb_DNA-bind_6 (PF13921): Myb-like DNA-binding domain
BE091809
4 CELF1interactorRRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
BE091809
5 CFTRsuppressorABC_membrane (PF00664, IPR001140): ABC transporter transmembrane region
ABC_tran (PF00005, IPR003439): ABC transporter
Roc (PF08477, IPR013684): Ras of Complex, Roc, domain of DAPkinase
SMC_N (PF02463, IPR003395): RecF/RecN/SMC N terminal domain
Rotamase_2 (PF13145, IPR000297): PPIC-type PPIASE domain
CFTR_R (PF14396, IPR025837): Cystic fibrosis TM conductance regulator (CFTR), regulator domain
BE091809
6 EIF4G1oncoproteinDUF1180 (PF06679, IPR009565): Protein of unknown function (DUF1180)
MA3 (PF02847, IPR003891, SM00544): MA3 domain
MIF4G (PF02854, IPR003890, SM00543): MIF4G domain
Neisseria_TspB (PF05616, IPR008708): Neisseria meningitidis TspB protein
W2 (PF02020, IPR003307, SM00515): eIF4-gamma/eIF5/eIF2-epsilon
BE091809
7 EIF4G3interactorMA3 (PF02847, IPR003891, SM00544): MA3 domain
MIF4G (PF02854, IPR003890, SM00543): MIF4G domain
W2 (PF02020, IPR003307, SM00515): eIF4-gamma/eIF5/eIF2-epsilon
BE091809
8 G3BP1interactorNTF2 (PF02136, IPR002075): Nuclear transport factor 2 (NTF2) domain
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
DUF3306 (PF11748, IPR021735): Protein of unknown function (DUF3306)
PTPRCAP (PF15713, IPR016553): Protein tyrosine phosphatase receptor type C-associated
BE091809
9 G3BP2interactorNTF2 (PF02136, IPR002075): Nuclear transport factor 2 (NTF2) domain
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
BE091809
10 GAR1interactorGar1 (PF04410, IPR007504): Gar1/Naf1 RNA binding regionBE091809
11 HECW2interactorC2 (PF00168, IPR000008, SM00239): C2 domain
WW (PF00397, IPR001202, SM00456): WW domain
HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
Cep57_CLD (PF14073, IPR025913): Centrosome localisation domain of Cep57
RFXA_RFXANK_bdg (PF15289, IPR029316): Regulatory factor X-associated C-terminal binding domain
HECW_N (PF16562, IPR032348): N-terminal domain of E3 ubiquitin-protein ligase HECW1 and 2
BE091809
12 IBTKinteractorBTB (PF00651, IPR013069, SM00225): BTB/POZ domain
RCC1 (PF00415, IPR000408): Regulator of chromosome condensation (RCC1) repeat
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
RCC1_2 (PF13540): Regulator of chromosome condensation (RCC1) repeat
Ank_5 (PF13857): Ankyrin repeats (many copies)
BE091809
13 IKBKGinteractorCENP-H (PF05837, IPR008426): Centromere protein H (CENP-H)
DUF725 (PF05267, IPR007931): Protein of unknown function (DUF725)
NEMO (PF11577, IPR021063): NF-kappa-B essential modulator NEMO
LLC1 (PF14945, IPR020339): Normal lung function maintenance, Low in Lung Cancer 1 protein
CC2-LZ (PF16516, IPR032419): Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator
BE091809
14 KLHDC3interactorKelch_2 (PF07646, IPR011498): Kelch motif
Kelch_3 (PF13415): Galactose oxidase, central domain
Kelch_4 (PF13418): Galactose oxidase, central domain
Kelch_5 (PF13854): Kelch motif
Kelch_6 (PF13964): Kelch motif
BE091809
15 KMT2EinteractorCAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
PHD (PF00628, IPR019787, SM00249): PHD-finger
SET (PF00856, IPR001214, SM00317): SET domain
MSA-2c (PF12238, IPR021060): Merozoite surface antigen 2c
DUF4124 (PF13511, IPR025392): Domain of unknown function (DUF4124)
PHD_3 (PF13922, IPR026905): PHD domain of transcriptional enhancer, Asx
DUF4666 (PF15697, IPR031421): Domain of unknown function (DUF4666)
PRIMA1 (PF16101): Proline-rich membrane anchor 1
BE091809
16 MDM2oncoproteinPinin_SDK_N (PF04697, IPR006787): pinin/SDK conserved region
Presenilin (PF01080, IPR001108): Presenilin
SWIB (PF02201, IPR003121, SM00151): SWIB/MDM2 domain
zf-FPG_IleRS (PF06827, IPR010663): Zinc finger found in FPG and IleRS
zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others
zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
BE091809
17 NOP56interactorCytochrom_NNT (PF03264, IPR005126): NapC/NirT cytochrome c family, N-terminal region
Nop (PF01798, IPR002687): snoRNA binding domain, fibrillarin
NOP5NT (PF08156, IPR012974): NOP5NT (NUC127) domain
RNA_polI_A34 (PF08208, IPR013240): DNA-directed RNA polymerase I subunit RPA34.5
SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal
BE091809
18 NPM1suppressorNucleoplasmin (PF03066): Nucleoplasmin
SDA1 (PF05285, IPR007949): SDA1
NPM1-C (PF16276, IPR032569): Nucleophosmin C-terminal domain
BE091809
19 NTRK1oncoproteinI-set (PF07679, IPR013098): Immunoglobulin I-set domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
LRR_8 (PF13855, IPR001611): Leucine rich repeat
TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain
BE091809
20 PABPC1oncoproteinRRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
PABP (PF00658, IPR002004, SM00517): Poly-adenylate binding protein, unique domain
YflT (PF11181, IPR025889): Heat induced stress protein YflT
BE091809
21 PCNAoncoproteinPCNA_C (PF02747, IPR022649): Proliferating cell nuclear antigen, C-terminal domain
PCNA_N (PF00705, IPR022648): Proliferating cell nuclear antigen, N-terminal domain
BE091809
22 PPP6R1interactorCENP-B_dimeris (PF09026, IPR015115): Centromere protein B dimerisation domain
SAPS (PF04499, IPR007587): SIT4 phosphatase-associated protein
WRNPLPNID (PF15017): Putative WW-binding domain and destruction box
BE091809
23 PPP6R3interactorSAPS (PF04499, IPR007587): SIT4 phosphatase-associated proteinBE091809
24 PRKAA1suppressorPkinase (PF00069, IPR000719): Protein kinase domain
AdenylateSensor (PF16579, IPR032270): Adenylate sensor of SNF1-like protein kinase
BE091809
25 PRKAA2suppressorPkinase (PF00069, IPR000719): Protein kinase domain
AdenylateSensor (PF16579, IPR032270): Adenylate sensor of SNF1-like protein kinase
BE091809
26 PTENsuppressorDSPc (PF00782, IPR020422, SM00195): Dual specificity phosphatase, catalytic domain
PTEN_C2 (PF10409, IPR014020): C2 domain of PTEN tumour-suppressor protein
BE091809
27 RAD51interactorRad51 (PF08423, IPR013632): Rad51
HHH_5 (PF14520): Helix-hairpin-helix domain
BE091809
28 RPL10suppressorRibosomal_L16 (PF00252, IPR016180): Ribosomal protein L16p/L10eBE091809
29 SCNN1AinteractorASC (PF00858, IPR001873): Amiloride-sensitive sodium channelBE091809
30 SF3B3interactorCPSF_A (PF03178, IPR004871): CPSF A subunit region
MMS1_N (PF10433): Mono-functional DNA-alkylating methyl methanesulfonate N-term
BE091809
31 SIRT6suppressorSIR2 (PF02146, IPR003000): Sir2 family
TPP_enzyme_M (PF00205, IPR012000): Thiamine pyrophosphate enzyme, central domain
BE091809
32 SNX3interactorPX (PF00787, IPR001683, SM00312): PX domainBE091809
33 TANKsuppressorDUF3713 (PF12506, IPR022186): Protein of unknown function (DUF3713)
TBD (PF12845, IPR024581): TBD domain
BE091809
34 TARDBPinteractorRRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)BE091809
35 TBPinteractorTBP (PF00352, IPR000814): Transcription factor TFIID (or TATA-binding protein, TBP)
EPL1 (PF10513, IPR019542): Enhancer of polycomb-like
Med3 (PF11593, IPR020998): Mediator complex subunit 3 fungal
BE091809
36 TBX21oncoproteinT-box (PF00907, IPR001699, SM00425): T-box
T-box_assoc (PF16176, IPR032385): T-box transcription factor-associated
BE091809
37 TP53suppressorDEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region
P53 (PF00870, IPR011615): P53 DNA-binding domain
P53_tetramer (PF07710, IPR010991): P53 tetramerisation motif
BE091809
38 TRAF6interactorSlyX (PF04102, IPR007236): SlyX
zf-TRAF (PF02176, IPR001293): TRAF-type zinc finger
zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
BE091809
39 TRPM8interactorIon_trans (PF00520, IPR005821): Ion transport proteinBE091809
40 TSKSinteractorTSKS (PF15358, IPR028214): Testis-specific serine kinase substrateBE091809
41 UBE2SinteractorALF (PF03752, IPR005506): Short repeats of unknown function
UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
BE091809
42 ULK1interactorPkinase (PF00069, IPR000719): Protein kinase domain
DUF3543 (PF12063, IPR022708): Domain of unknown function (DUF3543)
RCDG1 (PF15725, IPR031457): Renal cancer differentiation gene 1 protein
BE091809
43 USP10parental proteinPAM2 (PF07145, IPR009818): Ataxin-2 C-terminal region
UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase
YukD (PF08817, IPR024962): WXG100 protein secretion system (Wss), protein YukD
BE091809
44 USP15oncoproteinUCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase
DUSP (PF06337, IPR006615, SM00695): DUSP domain
Ubiquitin_3 (PF14836, IPR028135): Ubiquitin-like domain
BE091809
45 VCPinteractorAAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA)
CDC48_2 (PF02933, IPR004201, SM01072): Cell division protein 48 (CDC48), domain 2
CDC48_N (PF02359, IPR003338, SM01073): Cell division protein 48 (CDC48), N-terminal domain
TniB (PF05621, IPR008868): Bacterial TniB protein
Vps4_C (PF09336, IPR015415): Vps4 C terminal oligomerisation domain
DUF3944 (PF13099, IPR025217): Domain of unknown function (DUF3944)
BE091809
46 WAPLinteractorWAPL (PF07814, IPR022771): Wings apart-like protein regulation of heterochromatin
GAS (PF13851, IPR025593): Growth-arrest specific micro-tubule binding
BE091809
47 YBX1oncoproteinCSD (PF00313, IPR002059): 'Cold-shock' DNA-binding domain
PBP1_TM (PF14812, IPR032730): Transmembrane domain of transglycosylase PBP1 at N-terminal
FXR_C1 (PF16096, IPR032172): Fragile X-related 1 protein C-terminal region 2
BE091809
48 ZC3H12AinteractorRNase_Zc3h12a (PF11977, IPR021869): Zc3h12a-like Ribonuclease NYN domain
zf-CCCH_2 (PF14608): RNA-binding, Nab2-type zinc finger
BE091809
49 ZC3H18interactorFSAP_sig_propep (PF03032, IPR004275): Frog skin active peptide family signal and propeptide
Vfa1 (PF08432, IPR013640): AAA-ATPase Vps4-associated protein 1
DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777)
Peptidase_S49_N (PF08496, IPR013703): Peptidase family S49 N-terminal
Miga (PF10265, IPR019392): Mitoguardin
DUF3729 (PF12526, IPR022202): Protein of unknown function (DUF3729)
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
PBP1_TM (PF14812, IPR032730): Transmembrane domain of transglycosylase PBP1 at N-terminal
LRR19-TM (PF15176): Leucine-rich repeat family 19 TM domain
BE091809
50 ZNF281oncoproteinCAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
FYVE (PF01363, IPR000306, SM00064): FYVE zinc finger
GRP (PF07172, IPR010800): Glycine rich protein family
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
RhlB (PF12300, IPR022077): ATP-dependent RNA helicase RhlB
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
zf-C2H2_4 (PF13894): C2H2-type zinc finger
BE091809

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