Find Fusion Network

Enter
Fusion ID:
Protein names:


Level of PPIs:
or Upload text file:
Update repository
Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

Powered by Cytoscape Web for: parental proteins USH1C (from a repository: Mon Dec 5 07:09:59 2016)
Examples

Cytoscape Web will replace the contents your graph
PPI Properties:

Click on nodes
or edges

Layout Tree
Circle
Radial
Force Directed
Preset
Export graph
PDF file
SVG file
SIF file
XML file
GraphML file

Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)11
The number (and %) of the onco-proteins3 (27.27 %)
The number (and %) of the tumor suppressors0 (0.00 %)
Total number of binary PPIs (saturation %)16 (29.09 %)
The number (and %) of affected PPIs11 (68.75 %)
The number of possible different fusions5
PPI diameter2
PPI radius1
The average degree of PPI1.818
Assortativity coefficient0
The network average Clustering coefficient0.000
The number (and %) of a zero Clustering coefficients11 (100.00 %)
The number (and %) of a zero Betweenness Centrality10 (90.91 %)

ACTIVE INTERACTORS


List of the fusions

PPI for parental proteins: USH1C All fusions
: W22160;
Proteins found in more fusions QKI (see 3 fusions); RAC1 (see 1 fusions); USH1C (see 1 fusions); UBA1 (see 2 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 USH1Cparental protein11090.000CemA (PF03040, IPR004282): CemA family
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
SMN (PF06003, IPR010304): Survival motor neuron protein (SMN)
Saw1 (PF11561, IPR021624): Single strand annealing-weakened 1
DUF3393 (PF11873, IPR024570): Domain of unknown function (DUF3393)
DUF3567 (PF12091, IPR021951): Protein of unknown function (DUF3567)
PRIMA1 (PF16101): Proline-rich membrane anchor 1
2 CDH23interactor100Cadherin (PF00028, IPR002126, SM00112): Cadherin domain
DUF3364 (PF11844, IPR024564): Domain of unknown function (DUF3364)
Cadherin_3 (PF16184): Cadherin-like
3 CTNNAL1interactor100Vinculin (PF01044, IPR006077): Vinculin family
4 MIPOL1interactor200Bac_globin (PF01152, IPR001486): Bacterial-like globin
CDC37_N (PF03234, IPR013855, SM01071): Cdc37 N terminal kinase binding
DUF1003 (PF06210, IPR010406): Protein of unknown function (DUF1003)
ZapB (PF06005, IPR009252): Cell division protein ZapB
DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972)
Rho_Binding (PF08912, IPR015008): Rho Binding
IL17R_fnIII_D2 (PF16578): Interleukin 17 receptor D
5 MYO7Ainteractor100FERM_M (PF00373, IPR019748): FERM central domain
FERM_N (PF09379, IPR018979): FERM N-terminal domain
IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif
MyTH4 (PF00784, IPR000857, SM00139): MyTH4 domain
PID (PF00640, IPR006020, SM00462): Phosphotyrosine interaction domain (PTB/PID)
Med17 (PF10156, IPR019313): Subunit 17 of Mediator complex
Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain)
SH3_9 (PF14604, IPR001452): Variant SH3 domain
6 QKIprotein found in more fusions200KH_1 (PF00013, IPR004088, SM00322): KH domain
STAR_dimer (PF16544, IPR032377): Homodimerisation region of STAR domain protein
Quaking_NLS (PF16551, IPR032367): Putative nuclear localisation signal of quaking
7 RAC1oncoprotein200Ras (PF00071, IPR001806, SM00173): Ras family
8 SAAL1interactor100NA
9 UBA1protein found in more fusions200ThiF (PF00899, IPR000594): ThiF family
E1_UFD (PF09358, IPR018965, SM00985): Ubiquitin fold domain
UBA_e1_thiolCys (PF10585, IPR019572): Ubiquitin-activating enzyme active site
10 USHBP1interactor200DASH_Dam1 (PF08653, IPR013962): DASH complex subunit Dam1
HALZ (PF02183, IPR003106, SM00340): Homeobox associated leucine zipper
SlyX (PF04102, IPR007236): SlyX
MCC-bdg_PDZ (PF10506, IPR019536): PDZ domain of MCC-2 bdg protein for Usher syndrome
YlqD (PF11068, IPR021297): YlqD protein
DUF4404 (PF14357, IPR025516): Domain of unknown function (DUF4404)
CAGE1 (PF15066, IPR029381): Cancer-associated gene protein 1 family
TEX13 (PF15186, IPR028193): Testis-expressed sequence 13 protein family
11 WDR61interactor100WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain

B a c k    t o    T o p ⇑