Find Fusion Network

Visualization interactions

Powered by Cytoscape Web for: parental proteins UBQLN1 (from a repository: Fri Nov 11 22:42:33 2016)

Examples AFF1 MLL ACTN4 + MLLAFF1 + MLLALK + MSNALK + TFGALK + TPM3ALK + TPM4ASXL2 + KAT6AATF1 + FUSBCR + ABL1BCR + FGFR1CCND1 + TACSTD2CD74 + ROS1CDK6 + MLLCOL1A1 + PDGFBCREB3L2 + PPARGCREB3L2 + FUSCREBBP + KAT6ADAZAP1 + MEF2DELL + MLLEPS15 + MLLERG + EWSR1ERG + FUSERG + TMPRSS2ETV5 + TMPRSS2ETV6 + ABL1ETV6 + NTRK3ETV6 + PAX5EWSR1 + FLI1EWSR1 + WT1FOXO1 + PAX3FOXP1 + PAX5FRYL + MLLGAS7 + MLLGMPS + MLLGOLGA5 + RETHOOK3 + RETHOXC13 + NUP98HOXD13 + NUP98MECOM + RUNX1MKL1 + RBM15MLL + MLLT1MLL + MLLT4MLL + MLLT10MLL + PICALMMLLT10 + PICALMNCOA1 + PAX3NIN + PDGFRBNPM1 + RARANRG1 + ODZ4NTRK1 + TFGNUMA1 + RARANUP98 + PHF23PAX5 + ZNF521PBX1 + TCF3RET + TRIM27ROS1 + SLC34A2PML + RARAPRKAR1A + RARAPRKAR1A + RETRUNX1 + RUNX1T1RUNX1 + SH3D19	Cytoscape Web will replace the contents your graph	PPI Properties: Click on nodes or edges
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Statistics and Network structure information

Statistic of PPI Value(s) The number of interactors (fusion and proteins) 213 The number (and %) of the onco-proteins 55 (25.82 %) The number (and %) of the tumor suppressors 12 (5.63 %) Total number of binary PPIs (saturation %) 907 (4.02 %) The number (and %) of affected PPIs 213 (23.48 %) The number of possible different fusions 27 PPI diameter 2 PPI radius 1 The average degree of PPI 7.972 Assortativity coefficient -0.3736 The network average Clustering coefficient 0.514 The number (and %) of a zero Clustering coefficients 49 (23.00 %) The number (and %) of a zero Betweenness Centrality 105 (49.30 %)

ACTIVE INTERACTORS

List of the fusions
PPI for parental proteins: UBQLN1	All fusions : BF809109; BG005194;
Proteins found in more fusions	PSMC2 (see 1 fusions); APP (see 4 fusions); MCM7 (see 2 fusions); VCP (see 4 fusions); EPS15 (see 1 fusions); UBE2C (see 1 fusions); TICAM1 (see 1 fusions); GPX3 (see 5 fusions); PDCD6 (see 1 fusions); VPS26A (see 1 fusions); TNFRSF1A (see 2 fusions); UBQLN1 (see 2 fusions); UBE2D2 (see 2 fusions); AHCYL1 (see 3 fusions); RARA (see 4 fusions); UBQLN2 (see 2 fusions); PSMA7 (see 2 fusions); HTT (see 1 fusions); MIEF1 (see 1 fusions); EP300 (see 1 fusions); NDE1 (see 3 fusions); UBC (see 1 fusions); MTOR (see 1 fusions); PRPF40A (see 2 fusions); RASSF5 (see 2 fusions); GAPDH (see 2 fusions);

List of active interactors

#	Name	Type	Number of PPI (degree)	Clustering Coefficient	Betweenness Centrality	Domains (Pfam, InterPro, SMART): description
1	UBQLN1	parental protein	213	0.028	37577.914	Clathrin-link (PF09268, IPR015348): Clathrin, heavy-chain linker UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain XPC-binding (PF09280, IPR015360): XPC-binding domain ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family Fur_reg_FbpB (PF13040, IPR025004): Fur-regulated basic protein B FAM199X (PF15814, IPR029672): Protein family FAM199X
2	ABCC2	interactor	1	0	0	ABC_membrane (PF00664, IPR001140): ABC transporter transmembrane region ABC_tran (PF00005, IPR003439): ABC transporter DUF805 (PF05656, IPR008523): Protein of unknown function (DUF805) DUF87 (PF01935, IPR002789): Domain of unknown function DUF87 SMC_N (PF02463, IPR003395): RecF/RecN/SMC N terminal domain
3	ACOT7	interactor	3	1.000	0	4HBT (PF03061, IPR006683): Thioesterase superfamily NINJA_B (PF16136, IPR032310): Putative nuclear localisation signal
4	ADRM1	interactor	17	0.735	9.221	Proteasom_Rpn13 (PF04683, IPR006773): Proteasome complex subunit Rpn13 ubiquitin receptor GET2 (PF08690, IPR028143): GET complex subunit GET2 RPN13_C (PF16550, IPR032368): UCH-binding domain
5	AGPAT5	interactor	1	0	0	Acyltransferase (PF01553, IPR002123, SM00563): Acyltransferase Acyltransf_C (PF16076, IPR032098): Acyltransferase C-terminus
6	AGR2	interactor	3	0.667	0.182	Thioredoxin_7 (PF13899): Thioredoxin-like
7	AGR3	interactor	1	0	0	Thioredoxin_7 (PF13899): Thioredoxin-like
8	AHCYL1	suppressor	23	0.351	71.629	AdoHcyase (PF05221, IPR000043, SM00996): S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD (PF00670, IPR015878, SM00997): S-adenosyl-L-homocysteine hydrolase, NAD binding domain DUF515 (PF04415, IPR007509): Protein of unknown function (DUF515) Big_3_5 (PF16640, IPR032109): Bacterial Ig-like domain (group 3)
9	APP	protein found in more fusions	36	0.096	456.879	APP_N (PF02177, IPR015849, SM00006): Amyloid A4 N-terminal heparin-binding Beta-APP (PF03494, IPR013803): Beta-amyloid peptide (beta-APP) BUD22 (PF09073, IPR015158): BUD22 IncA (PF04156, IPR007285): IncA protein Kunitz_BPTI (PF00014, IPR002223, SM00131): Kunitz/Bovine pancreatic trypsin inhibitor domain APP_amyloid (PF10515, IPR019543): beta-amyloid precursor protein C-terminus APP_Cu_bd (PF12924, IPR011178): Copper-binding of amyloid precursor, CuBD APP_E2 (PF12925, IPR024329): E2 domain of amyloid precursor protein
10	ASNS	oncoprotein	4	0.667	1.125	Asn_synthase (PF00733, IPR001962): Asparagine synthase GATase_7 (PF13537, IPR000583): Glutamine amidotransferase domain
11	ATP6V1B2	interactor	10	0.467	12.045	ATP-synt_ab (PF00006, IPR000194): ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N (PF02874, IPR004100): ATP synthase alpha/beta family, beta-barrel domain DUF2481 (PF10654, IPR018916): Protein of unknown function (DUF2481)
12	ATP6V1H	interactor	4	0.667	1.400	V-ATPase_H_N (PF03224, IPR004908): V-ATPase subunit H V-ATPase_H_C (PF11698, IPR011987): V-ATPase subunit H
13	ATXN3	interactor	11	0.444	11.864	Josephin (PF02099, IPR006155): Josephin UIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif SUIM_assoc (PF16619): Unstructured region C-term to UIM in Ataxin3
14	BCL2L10	interactor	2	0	0	Bcl-2 (PF00452, IPR026298): Apoptosis regulator proteins, Bcl-2 family
15	BPIFA1	interactor	3	1.000	0	LBP_BPI_CETP (PF01273, IPR017942, SM00328): LBP / BPI / CETP family, N-terminal domain
16	C12orf10	interactor	2	1.000	0	UPF0160 (PF03690, IPR003226): Uncharacterised protein family (UPF0160)
17	C1QA	oncoprotein	3	0.667	0.286	C1q (PF00386, IPR001073, SM00110): C1q domain Collagen (PF01391, IPR008160): Collagen triple helix repeat (20 copies) DUF1860 (PF08949, IPR015044): Domain of unknown function (DUF1860)
18	C1QTNF2	interactor	2	1.000	0	C1q (PF00386, IPR001073, SM00110): C1q domain Collagen (PF01391, IPR008160): Collagen triple helix repeat (20 copies) DUF1860 (PF08949, IPR015044): Domain of unknown function (DUF1860)
19	CALU	interactor	5	0.900	0.167	EF-hand_6 (PF13405, IPR002048): EF-hand domain EF-hand_7 (PF13499, IPR011992): EF-hand domain pair EF-hand_8 (PF13833, IPR002048): EF-hand domain pair
20	CCL7	oncoprotein	2	0	0	IL8 (PF00048, IPR001811, SM00199): Small cytokines (intecrine/chemokine), interleukin-8 like DUF4725 (PF15854, IPR031713): Domain of unknown function (DUF4725)
21	CD3D	interactor	2	1.000	0	DAP10 (PF07213, IPR009861): DAP10 membrane protein ITAM (PF02189, IPR003110, SM00077): Immunoreceptor tyrosine-based activation motif Ig_4 (PF16680, IPR032052): T-cell surface glycoprotein CD3 delta chain
22	CD99	interactor	2	1.000	0	CD99L2 (PF12301, IPR022078): CD99 antigen like protein 2
23	CD99L2	interactor	2	1.000	0	CD99L2 (PF12301, IPR022078): CD99 antigen like protein 2
24	CHGB	interactor	2	1.000	0	Granin (PF01271, IPR001990): Granin (chromogranin or secretogranin)
25	CLNS1A	interactor	8	0.464	4.974	Voldacs (PF03517): Regulator of volume decrease after cellular swelling
26	COL10A1	interactor	1	0	0	C1q (PF00386, IPR001073, SM00110): C1q domain Collagen (PF01391, IPR008160): Collagen triple helix repeat (20 copies) DUF1860 (PF08949, IPR015044): Domain of unknown function (DUF1860)
27	COL1A2	oncoprotein	1	0	0	COLFI (PF01410, IPR000885, SM00038): Fibrillar collagen C-terminal domain Collagen (PF01391, IPR008160): Collagen triple helix repeat (20 copies) DUF1860 (PF08949, IPR015044): Domain of unknown function (DUF1860)
28	COLGALT2	interactor	2	1.000	0	Aminotran_4 (PF01063, IPR001544): Amino-transferase class IV Glyco_transf_25 (PF01755, IPR002654): Glycosyltransferase family 25 (LPS biosynthesis protein) Glyco_tranf_2_4 (PF13704): Glycosyl transferase family 2
29	COMTD1	interactor	3	0.667	0.667	FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
30	CSTF2	interactor	5	0.800	0.848	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF_C (PF14304, IPR026896): Transcription termination and cleavage factor C-terminal CSTF2_hinge (PF14327, IPR025742): Hinge domain of cleavage stimulation factor subunit 2
31	CSTF2T	interactor	4	1.000	0	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF_C (PF14304, IPR026896): Transcription termination and cleavage factor C-terminal CSTF2_hinge (PF14327, IPR025742): Hinge domain of cleavage stimulation factor subunit 2
32	CTAG1B	interactor	1	0	0	Pcc1 (PF09341, IPR015419): Transcription factor Pcc1
33	CTAG2	interactor	1	0	0	Pcc1 (PF09341, IPR015419): Transcription factor Pcc1
34	CYB5R1	interactor	3	1.000	0	FAD_binding_6 (PF00970, IPR008333): Oxidoreductase FAD-binding domain NAD_binding_1 (PF00175, IPR001433): Oxidoreductase NAD-binding domain
35	DCTPP1	interactor	6	0.600	2.867	MazG-like (PF12643, IPR025984): MazG-like family
36	DEFA6	interactor	2	1.000	0	Defensin_1 (PF00323, IPR006081): Mammalian defensin Defensin_propep (PF00879, IPR002366): Defensin propeptide
37	DNAJB2	interactor	7	0.429	6.123	DnaJ (PF00226, IPR001623, SM00271): DnaJ domain UIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif
38	EFEMP2	interactor	2	1.000	0	EGF_CA (PF07645, IPR001881, SM00179): Calcium-binding EGF domain hEGF (PF12661, IPR013032): Human growth factor-like EGF cEGF (PF12662, IPR026823): Complement Clr-like EGF-like Adipogenin (PF15202, IPR027938): Adipogenin
39	EP300	oncoprotein	8	0.476	7.200	Creb_binding (PF09030, IPR014744): Creb binding DUF902 (PF06001, IPR010303): Domain of Unknown Function (DUF902) Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region KIX (PF02172, IPR003101): KIX domain RR_TM4-6 (PF06459, IPR009460): Ryanodine Receptor TM 4-6 TPX2 (PF06886, IPR027329): Targeting protein for Xklp2 (TPX2) zf-TAZ (PF02135, IPR000197, SM00551): TAZ zinc finger HAT_KAT11 (PF08214, IPR013178): Histone acetylation protein Bromodomain (PF00439, IPR001487, SM00297): Bromodomain ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type
40	EPS15	oncoprotein	12	0.455	12.684	Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein UIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif DUF3391 (PF11871, IPR021812): Domain of unknown function (DUF3391) EF-hand_4 (PF12763, IPR000261): Cytoskeletal-regulatory complex EF hand EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
41	EPS15L1	oncoprotein	2	1.000	0	CALCOCO1 (PF07888, IPR012852): Calcium binding and coiled-coil domain (CALCOCO1) like Pinin_SDK_memA (PF04696, IPR006786): pinin/SDK/memA/ protein conserved region UIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif EF-hand_4 (PF12763, IPR000261): Cytoskeletal-regulatory complex EF hand
42	ERP27	interactor	2	1.000	0	Thioredoxin_6 (PF13848): Thioredoxin-like domain
43	ETNK1	interactor	1	0	0	Choline_kinase (PF01633): Choline/ethanolamine kinase RskA (PF10099, IPR018764): Anti-sigma-K factor rskA
44	F8	interactor	1	0	0	Cu-oxidase (PF00394, IPR001117): Multicopper oxidase Cu-oxidase_2 (PF07731, IPR011706): Multicopper oxidase Cu-oxidase_3 (PF07732, IPR011707): Multicopper oxidase F5_F8_type_C (PF00754, IPR000421, SM00231): F5/8 type C domain PBP1_TM (PF14812, IPR032730): Transmembrane domain of transglycosylase PBP1 at N-terminal
45	FAM127A	interactor	2	1.000	0	DUF4939 (PF16297, IPR032549): Domain of unknown function (DUF4939)
46	FAM127B	interactor	2	1.000	0	DUF4939 (PF16297, IPR032549): Domain of unknown function (DUF4939)
47	FAM127C	interactor	1	0	0	DUF4939 (PF16297, IPR032549): Domain of unknown function (DUF4939)
48	FAM189A2	interactor	5	0.400	2.733	CD20 (PF04103, IPR007237): CD20-like family
49	FAM86B3P	interactor	2	1.000	0	NA
50	FAS	suppressor	5	0.500	2.667	Death (PF00531, IPR000488, SM00005): Death domain TNFR_c6 (PF00020, IPR001368, SM00208): TNFR/NGFR cysteine-rich region Stn1_C (PF12659, IPR024263): Telomere capping C-terminal wHTH
51	FBXO25	suppressor	10	0.356	14.887	Elongin_A (PF06881, IPR010684): RNA polymerase II transcription factor SIII (Elongin) subunit A
52	FCGR2A	interactor	2	1.000	0	DUF3827 (PF12877, IPR024606): Domain of unknown function (DUF3827) Ig_2 (PF13895, IPR007110): Immunoglobulin domain ECSCR (PF15820, IPR026247): Endothelial cell-specific chemotaxis regulator
53	FGF7	oncoprotein	1	0	0	FGF (PF00167, IPR002209, SM00442): Fibroblast growth factor
54	FKBP2	interactor	3	1.000	0	FKBP_C (PF00254, IPR001179): FKBP-type peptidyl-prolyl cis-trans isomerase
55	FN1	oncoprotein	22	0.173	136.904	fn1 (PF00039, IPR000083, SM00058): Fibronectin type I domain fn2 (PF00040, IPR000562, SM00059): Fibronectin type II domain fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369)
56	FZD7	interactor	2	1.000	0	Frizzled (PF01534, IPR000539): Frizzled/Smoothened family membrane region Fz (PF01392, IPR020067, SM00063): Fz domain
57	GABRA1	interactor	2	1.000	0	Neur_chan_LBD (PF02931, IPR006202): Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb (PF02932, IPR006029): Neurotransmitter-gated ion-channel transmembrane region
58	GABRA2	interactor	1	0	0	Neur_chan_LBD (PF02931, IPR006202): Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb (PF02932, IPR006029): Neurotransmitter-gated ion-channel transmembrane region
59	GABRA3	interactor	1	0	0	Neur_chan_LBD (PF02931, IPR006202): Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb (PF02932, IPR006029): Neurotransmitter-gated ion-channel transmembrane region
60	GABRA6	interactor	1	0	0	Neur_chan_LBD (PF02931, IPR006202): Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb (PF02932, IPR006029): Neurotransmitter-gated ion-channel transmembrane region
61	GABRB1	interactor	1	0	0	Neur_chan_LBD (PF02931, IPR006202): Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb (PF02932, IPR006029): Neurotransmitter-gated ion-channel transmembrane region
62	GABRB2	interactor	1	0	0	Neur_chan_LBD (PF02931, IPR006202): Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb (PF02932, IPR006029): Neurotransmitter-gated ion-channel transmembrane region
63	GABRB3	interactor	1	0	0	Neur_chan_LBD (PF02931, IPR006202): Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb (PF02932, IPR006029): Neurotransmitter-gated ion-channel transmembrane region
64	GABRD	interactor	2	1.000	0	Neur_chan_LBD (PF02931, IPR006202): Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb (PF02932, IPR006029): Neurotransmitter-gated ion-channel transmembrane region PsbY (PF06298, IPR009388): Photosystem II protein Y (PsbY)
65	GAPDH	oncoprotein	14	0.256	42.651	Gp_dh_C (PF02800, IPR020829): Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N (PF00044, IPR020828, SM00846): Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain OstA (PF03968, IPR005653): OstA-like protein
66	GHRL	oncoprotein	1	0	0	Motilin_assoc (PF04643, IPR006737): Motilin/ghrelin-associated peptide Motilin_ghrelin (PF04644, IPR006738): Motilin/ghrelin
67	GIT2	interactor	2	0	0	ArfGap (PF01412, IPR001164, SM00105): Putative GTPase activating protein for Arf Sen15 (PF09631, IPR018593): Sen15 protein GIT_SHD (PF08518, IPR013724, SM00555): Spa2 homology domain (SHD) of GIT GIT1_C (PF12205, IPR022018): G protein-coupled receptor kinase-interacting protein 1 C term Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) DUF4482 (PF14818, IPR027882): Domain of unknown function (DUF4482) GIT_CC (PF16559, IPR032352): GIT coiled-coil Rho guanine nucleotide exchange factor
68	GKAP1	interactor	4	1.000	0	CENP-H (PF05837, IPR008426): Centromere protein H (CENP-H) Ribosomal_L30_N (PF08079, IPR012988): Ribosomal L30 N-terminal domain PKcGMP_CC (PF16808, IPR031831): Coiled-coil N-terminus of cGMP-dependent protein kinase
69	GNB1	interactor	3	0.667	0.500	Myc-LZ (PF02344, IPR003327): Myc leucine zipper domain WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
70	GNPDA1	interactor	4	0.833	0.667	Glucosamine_iso (PF01182, IPR006148): Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase
71	GPX3	suppressor	2	0	0	GSHPx (PF00255, IPR000889): Glutathione peroxidase
72	GRM2	interactor	1	0	0	7tm_3 (PF00003, IPR017978): 7 transmembrane sweet-taste receptor of 3 GCPR ANF_receptor (PF01094, IPR001828): Receptor family ligand binding region NCD3G (PF07562, IPR011500): Nine Cysteines Domain of family 3 GPCR
73	GYPB	interactor	1	0	0	Glycophorin_A (PF01102, IPR001195): Glycophorin A Ibs_toxin (PF13956, IPR025881): Toxin Ibs, type I toxin-antitoxin system
74	HERC3	interactor	9	0.556	8.695	RCC1 (PF00415, IPR000408): Regulator of chromosome condensation (RCC1) repeat HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase) RCC1_2 (PF13540): Regulator of chromosome condensation (RCC1) repeat
75	HERPUD1	oncoprotein	8	0.500	3.906	Neisseria_TspB (PF05616, IPR008708): Neisseria meningitidis TspB protein ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
76	HGS	interactor	15	0.305	52.432	FYVE (PF01363, IPR000306, SM00064): FYVE zinc finger UIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif VHS (PF00790, IPR002014, SM00288): VHS domain EF-1_beta_acid (PF10587, IPR018940): Eukaryotic elongation factor 1 beta central acidic region Hrs_helical (PF12210, IPR024641): Hepatocyte growth factor-regulated tyrosine kinase substrate PIEZO (PF15917, IPR031805): Piezo
77	HK2	interactor	4	0.500	2.125	Hexokinase_1 (PF00349, IPR022672): Hexokinase Hexokinase_2 (PF03727, IPR022673): Hexokinase
78	HSD17B12	interactor	5	0.800	0.422	adh_short (PF00106, IPR002198): short chain dehydrogenase
79	HSPA13	interactor	3	1.000	0	HSP70 (PF00012, IPR013126): Hsp70 protein
80	HSPA1L	interactor	7	0.333	8.250	HSP70 (PF00012, IPR013126): Hsp70 protein
81	HTT	protein found in more fusions	9	0.429	11.567	HEAT (PF02985, IPR000357): HEAT repeat SPX (PF03105, IPR004331): SPX domain TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit DUF3652 (PF12372, IPR024613): Huntingtin protein region Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region HEAT_EZ (PF13513): HEAT-like repeat HEAT_2 (PF13646): HEAT repeats
82	HYPK	interactor	3	0.667	0.500	Utp11 (PF03998, IPR007144): Utp11 protein
83	IGL	oncoprotein	1	0	0	NA
84	IGLC1	interactor	2	1.000	0	C1-set (PF07654, IPR003597, SM00407): Immunoglobulin C1-set domain
85	IGLV2-14	interactor	1	0	0	V-set (PF07686, IPR013106): Immunoglobulin V-set domain
86	IL6ST	oncoprotein	1	0	0	fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain IL6Ra-bind (PF09240, IPR015321): Interleukin-6 receptor alpha chain, binding Lep_receptor_Ig (PF06328, IPR010457): Ig-like C2-type domain Pur_ac_phosph_N (PF16656, IPR015914): Purple acid Phosphatase, N-terminal domain
87	INSIG2	interactor	9	0.639	3.569	INSIG (PF07281, IPR025929): Insulin-induced protein (INSIG)
88	IST1	interactor	3	0.667	0.667	Ist1 (PF03398, IPR005061): Regulator of Vps4 activity in the MVB pathway
89	ITPRIPL1	interactor	2	1.000	0	Mab-21 (PF03281, IPR024810): Mab-21 protein
90	KLHL42	interactor	3	1.000	0	BACK (PF07707, IPR011705, SM00875): BTB And C-terminal Kelch BTB (PF00651, IPR013069, SM00225): BTB/POZ domain Kelch_1 (PF01344, IPR006652, SM00612): Kelch motif Kelch_3 (PF13415): Galactose oxidase, central domain Kelch_5 (PF13854): Kelch motif Kelch_6 (PF13964): Kelch motif
91	LITAF	suppressor	3	1.000	0	zf-LITAF-like (PF10601, IPR006629, SM00714): LITAF-like zinc ribbon domain DUF3824 (PF12868, IPR024436): Domain of unknwon function (DUF3824)
92	MANBAL	interactor	1	0	0	UPF0239 (PF06783, IPR009621): Uncharacterised protein family (UPF0239)
93	MAP1LC3A	interactor	9	0.472	11.784	Atg8 (PF02991, IPR004241): Autophagy protein Atg8 ubiquitin like
94	MAP3K1	oncoprotein	13	0.318	20.868	zf-Di19 (PF05605, IPR008598): Drought induced 19 protein (Di19), zinc-binding Pkinase (PF00069, IPR000719): Protein kinase domain zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain Phostensin_N (PF13916, IPR025903): PP1-regulatory protein, Phostensin N-terminal
95	MCM7	protein found in more fusions	10	0.389	12.206	MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family MCM_N (PF14551, IPR027925): MCM N-terminal domain MCM_OB (PF17207): MCM OB domain
96	MIEF1	protein found in more fusions	2	0	0	Mab-21 (PF03281, IPR024810): Mab-21 protein
97	MIEF2	interactor	2	1.000	0	Mab-21 (PF03281, IPR024810): Mab-21 protein
98	MLLT6	oncoprotein	4	0.500	1.098	DUF572 (PF04502, IPR007590): Family of unknown function (DUF572) HALZ (PF02183, IPR003106, SM00340): Homeobox associated leucine zipper SpoIIIAH (PF12685, IPR024232): SpoIIIAH-like protein zf-HC5HC2H (PF13771): PHD-like zinc-binding domain PHD_2 (PF13831): PHD-finger zf-HC5HC2H_2 (PF13832): PHD-zinc-finger like domain SOBP (PF15279, IPR026092): Sine oculis-binding protein SKA2 (PF16740, IPR026762): Spindle and kinetochore-associated protein 2
99	MTHFD1	interactor	6	0.533	4.289	FTHFS (PF01268, IPR000559): Formate--tetrahydrofolate ligase THF_DHG_CYH (PF00763, IPR020630): Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C (PF02882, IPR020631): Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain
100	MTOR	oncoprotein	5	0.500	1.667	DUF1104 (PF06518, IPR009488): Protein of unknown function (DUF1104) EPSP_synthase (PF00275, IPR001986): EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) FAT (PF02259, IPR003151): FAT domain FATC (PF02260, IPR003152): FATC domain HEAT (PF02985, IPR000357): HEAT repeat FRB_dom (PF08771, IPR009076): FKBP12-rapamycin binding domain V-ATPase_H_N (PF03224, IPR004908): V-ATPase subunit H PI3_PI4_kinase (PF00454, IPR000403, SM00146): Phosphatidylinositol 3- and 4-kinase DUF3385 (PF11865, IPR024585): Domain of unknown function (DUF3385) HEAT_EZ (PF13513): HEAT-like repeat HEAT_2 (PF13646): HEAT repeats TPR_19 (PF14559): Tetratricopeptide repeat
101	NAXD	interactor	2	1.000	0	Carb_kinase (PF01256, IPR000631): Carbohydrate kinase GHMP_kinases_N (PF00288, IPR006204): GHMP kinases N terminal domain
102	NBL1	oncoprotein	1	0	0	DAN (PF03045, IPR004133): DAN domain DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region
103	NDE1	protein found in more fusions	2	0	0	NUDE_C (PF04880, IPR006964): NUDE protein, C-terminal conserved region TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein PRKG1_interact (PF15898, IPR031775): cGMP-dependent protein kinase interacting domain
104	NGLY1	interactor	5	0.600	0.936	PUB (PF09409, IPR018997): PUB domain Rad4 (PF03835, IPR018325): Rad4 transglutaminase-like domain PAW (PF04721, IPR006588, SM00613): PNGase C-terminal domain, mannose-binding module PAW Transglut_core (PF01841, IPR002931, SM00460): Transglutaminase-like superfamily
105	NME3	oncoprotein	3	0.667	0.182	NDK (PF00334, IPR001564, SM00562): Nucleoside diphosphate kinase
106	NPPA	interactor	2	1.000	0	ANP (PF00212, IPR000663, SM00183): Atrial natriuretic peptide
107	NPY	oncoprotein	1	0	0	Hormone_3 (PF00159, IPR001955): Pancreatic hormone peptide
108	NTRK1	oncoprotein	47	0.150	669.532	I-set (PF07679, IPR013098): Immunoglobulin I-set domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase LRR_8 (PF13855, IPR001611): Leucine rich repeat TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain
109	NUBP1	interactor	4	0.667	2.000	DUF258 (PF03193, IPR004881): Protein of unknown function, DUF258 ParA (PF10609, IPR019591): NUBPL iron-transfer P-loop NTPase
110	NUP58	interactor	3	1.000	0	Nucleoporin_FG2 (PF15967): Nucleoporin FG repeated region
111	ORAI1	interactor	1	0	0	Orai-1 (PF07856, IPR012446): Mediator of CRAC channel activity
112	P4HB	interactor	12	0.418	18.709	Glycos_trans_3N (PF02885, IPR017459): Glycosyl transferase family, helical bundle domain Thioredoxin (PF00085, IPR013766): Thioredoxin Thioredoxin_6 (PF13848): Thioredoxin-like domain
113	PARVA	oncoprotein	4	0.667	1.333	CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain MSA-2c (PF12238, IPR021060): Merozoite surface antigen 2c
114	PBXIP1	interactor	4	0.500	1.792	DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972) bZIP_2 (PF07716, IPR004827, SM00338): Basic region leucine zipper MscS_porin (PF12795, IPR024393): Mechanosensitive ion channel porin domain
115	PDCD6	oncoprotein	6	0.700	2.667	EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
116	PIK3IP1	interactor	1	0	0	Kringle (PF00051, IPR000001): Kringle domain Ost4 (PF10215, IPR018943): Oligosaccaryltransferase
117	PLA2G16	suppressor	2	1.000	0	LRAT (PF04970, IPR007053): Lecithin retinol acyltransferase
118	PNMA1	oncoprotein	5	0.600	2.667	PNMA (PF14893, IPR026523): PNMA
119	PPIB	interactor	10	0.378	20.642	Pro_isomerase (PF00160, IPR002130): Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD
120	PPIC	interactor	2	1.000	0	Pro_isomerase (PF00160, IPR002130): Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD
121	PRAP1	interactor	1	0	0	3HBOH (PF10605, IPR016582): 3HB-oligomer hydrolase (3HBOH) PRAP (PF15314, IPR027922): Proline-rich acidic protein 1, pregnancy-specific uterine
122	PRB1	interactor	1	0	0	Pro-rich (PF15240, IPR026086): Proline-rich
123	PRPF40A	protein found in more fusions	9	0.536	6.725	FF (PF01846, IPR002713, SM00441): FF domain MCR_alpha (PF02249, IPR009047): Methyl-coenzyme M reductase alpha subunit, C-terminal domain Transformer (PF06495, IPR010519): Fruit fly transformer protein WW (PF00397, IPR001202, SM00456): WW domain YqzE (PF14038, IPR025622): YqzE-like protein SPT6_acidic (PF14632, IPR028083): Acidic N-terminal SPT6 SRRM_C (PF15230, IPR029360): Serine/arginine repetitive matrix protein C-terminus SOBP (PF15279, IPR026092): Sine oculis-binding protein IHABP4_N (PF16174, IPR032381): Intracellular hyaluronan-binding protein 4 N-terminal
124	PSEN1	oncoprotein	10	0.444	12.595	Presenilin (PF01080, IPR001108): Presenilin LRRC37AB_C (PF14914, IPR029423): LRRC37A/B like protein 1 C-terminal domain
125	PSEN2	oncoprotein	4	1.000	0	Herpes_LMP1 (PF05297, IPR007961): Herpesvirus latent membrane protein 1 (LMP1) Presenilin (PF01080, IPR001108): Presenilin
126	PSMA5	oncoprotein	20	0.558	30.577	Proteasome (PF00227, IPR001353): Proteasome subunit Proteasome_A_N (PF10584, IPR000426, SM00948): Proteasome subunit A N-terminal signature
127	PSMA6	interactor	21	0.562	42.898	Proteasome (PF00227, IPR001353): Proteasome subunit Proteasome_A_N (PF10584, IPR000426, SM00948): Proteasome subunit A N-terminal signature
128	PSMA7	protein found in more fusions	21	0.605	25.045	Proteasome (PF00227, IPR001353): Proteasome subunit Peptidase_C65 (PF10275, IPR019400): Peptidase C65 Otubain Proteasome_A_N (PF10584, IPR000426, SM00948): Proteasome subunit A N-terminal signature
129	PSMC2	protein found in more fusions	24	0.534	45.447	AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA)
130	PSMD14	interactor	17	0.787	6.476	JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg (PF13012, IPR024969): Maintenance of mitochondrial structure and function
131	PSMD2	oncoprotein	21	0.486	62.256	PC_rep (PF01851, IPR002015): Proteasome/cyclosome repeat THAP (PF05485, IPR006612, SM00980): THAP domain HEAT_2 (PF13646): HEAT repeats
132	PSMD3	interactor	16	0.725	13.415	Rpn3_C (PF08375, IPR013586): Proteasome regulatory subunit C-terminal TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat PCI (PF01399, IPR000717, SM00088): PCI domain Fis1_TPR_C (PF14853, IPR028061): Fis1 C-terminal tetratricopeptide repeat TSKS (PF15358, IPR028214): Testis-specific serine kinase substrate
133	PSMD4	interactor	28	0.434	91.822	UIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif VWA_2 (PF13519, IPR002035): von Willebrand factor type A domain
134	PSMD6	interactor	16	0.683	16.938	RPN7 (PF10602, IPR019585): 26S proteasome subunit RPN7 PCI (PF01399, IPR000717, SM00088): PCI domain
135	PTN	oncoprotein	5	0.667	1.000	PTN_MK_C (PF01091, IPR020090): PTN/MK heparin-binding protein family, C-terminal domain PTN_MK_N (PF05196, IPR020089): PTN/MK heparin-binding protein family, N-terminal domain
136	PYM1	interactor	3	1.000	0	CcmD (PF04995, IPR007078): Heme exporter protein D (CcmD) Mago-bind (PF09282, IPR015362): Mago binding AAA_23 (PF13476): AAA domain
137	RAD23A	oncoprotein	29	0.368	136.973	UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain XPC-binding (PF09280, IPR015360): XPC-binding domain ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
138	RAD23B	suppressor	16	0.608	17.134	K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain XPC-binding (PF09280, IPR015360): XPC-binding domain ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family DUF3123 (PF11321, IPR021470): Protein of unknown function (DUF3123)
139	RAP1GDS1	oncoprotein	5	0.700	2.000	Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat WAPL (PF07814, IPR022771): Wings apart-like protein regulation of heterochromatin Vps39_1 (PF10366, IPR019452): Vacuolar sorting protein 39 domain 1 V-ATPase_H_C (PF11698, IPR011987): V-ATPase subunit H HEAT_2 (PF13646): HEAT repeats Nitr_red_bet_C (PF14711, IPR029263): Respiratory nitrate reductase beta C-terminal SIL1 (PF16782, IPR031884): Nucleotide exchange factor SIL1
140	RARA	oncoprotein	7	0.333	6.633	zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
141	RASSF5	suppressor	3	1.000	0	RA (PF00788, IPR000159, SM00314): Ras association (RalGDS/AF-6) domain C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain) Nore1-SARAH (PF16517, IPR011524): Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain
142	RBMS1	interactor	2	1.000	0	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
143	RELA	oncoprotein	13	0.455	20.377	DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region RHD_DNA_bind (PF00554, IPR011539): Rel homology DNA-binding domain RHD_dimer (PF16179, IPR032397): Rel homology dimerisation domain
144	RIC8A	interactor	3	0.667	0.125	PUL (PF08324, IPR013535): PUL domain Ric8 (PF10165, IPR019318): Guanine nucleotide exchange factor synembryn
145	RNF185	interactor	17	0.408	32.982	zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
146	RNF208	interactor	2	1.000	0	GcpE (PF04551, IPR004588): GcpE protein zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger zf-C3HC4_4 (PF15227): zinc finger of C3HC4-type, RING
147	RPN1	oncoprotein	12	0.379	19.547	Ribophorin_I (PF04597, IPR007676): Ribophorin I CtIP_N (PF10482, IPR019518): Tumour-suppressor protein CtIP N-terminal domain
148	RSRC2	interactor	5	0.500	1.822	Pap_E4 (PF02711, IPR003861): E4 protein PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 SMAP (PF15477, IPR028124): Small acidic protein family
149	SCG2	interactor	2	1.000	0	Granin (PF01271, IPR001990): Granin (chromogranin or secretogranin)
150	SCG5	interactor	2	1.000	0	Secretogranin_V (PF05281, IPR007945): Neuroendocrine protein 7B2 precursor (Secretogranin V)
151	SCMH1	interactor	3	1.000	0	MBT (PF02820, IPR004092, SM00561): mbt repeat SAM_1 (PF00536, IPR021129, SM00454): SAM domain (Sterile alpha motif) SLED (PF12140, IPR021987): SLED domain RBR (PF17208): RNA binding Region
152	SERPINE1	interactor	3	1.000	0	Serpin (PF00079, IPR023796, SM00093): Serpin (serine protease inhibitor)
153	SERPINI2	suppressor	2	1.000	0	Serpin (PF00079, IPR023796, SM00093): Serpin (serine protease inhibitor)
154	SFXN1	interactor	3	1.000	0	Mtc (PF03820, IPR004686): Tricarboxylate carrier
155	SHFM1	interactor	19	0.620	22.847	CLLAC (PF15675, IPR031379): CLLAC-motif containing domain
156	SIL1	interactor	2	1.000	0	Fes1 (PF08609, IPR013918): Nucleotide exchange factor Fes1 HEAT (PF02985, IPR000357): HEAT repeat RTTN_N (PF14726, IPR029249): Rotatin, an armadillo repeat protein, centriole functioning DUF4704 (PF15787, IPR031570): Domain of unknown function (DUF4704)
157	SLC29A2	interactor	1	0	0	Nucleoside_tran (PF01733, IPR002259): Nucleoside transporter DUF2070 (PF09843, IPR019204): Predicted membrane protein (DUF2070)
158	SMAD9	interactor	5	0.500	2.667	MH1 (PF03165, IPR003619, SM00523): MH1 domain MH2 (PF03166, IPR001132, SM00524): MH2 domain
159	SMIM2	interactor	1	0	0	NA
160	SMR3B	interactor	1	0	0	PROL5-SMR (PF15621, IPR026288): Proline-rich submaxillary gland androgen-regulated family
161	SNRNP70	interactor	10	0.289	22.384	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MIP-T3 (PF10243): Microtubule-binding protein MIP-T3 U1snRNP70_N (PF12220, IPR022023): U1 small nuclear ribonucleoprotein of 70kDa MW N terminal
162	SPARC	suppressor	1	0	0	FOLN (PF09289, IPR015369, SM00274): Follistatin/Osteonectin-like EGF domain Kazal_1 (PF00050, IPR002350): Kazal-type serine protease inhibitor domain SPARC_Ca_bdg (PF10591, IPR019577): Secreted protein acidic and rich in cysteine Ca binding region
163	SRGN	interactor	2	1.000	0	Serglycin (PF04360, IPR007455): Serglycin
164	SSSCA1	interactor	19	0.444	31.305	Auto_anti-p27 (PF06677, IPR009563): Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27)
165	STAM2	interactor	12	0.409	25.202	GAT (PF03127, IPR004152): GAT domain UIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif VHS (PF00790, IPR002014, SM00288): VHS domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
166	STMN1	interactor	7	0.381	6.655	Stathmin (PF00836, IPR000956): Stathmin family
167	STMN3	interactor	1	0	0	Stathmin (PF00836, IPR000956): Stathmin family
168	TARDBP	interactor	12	0.382	19.830	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
169	TFF1	oncoprotein	3	1.000	0	Trefoil (PF00088, IPR000519, SM00018): Trefoil (P-type) domain
170	TICAM1	protein found in more fusions	3	1.000	0	Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator RHIM (PF12721, IPR025735): RIP homotypic interaction motif TIR_2 (PF13676, IPR000157): TIR domain
171	TLR4	interactor	3	0.667	1.000	LRR_1 (PF00560, IPR001611): Leucine Rich Repeat TIR (PF01582, IPR000157, SM00255): TIR domain LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies) LRR_8 (PF13855, IPR001611): Leucine rich repeat LRR_9 (PF14580): Leucine-rich repeat
172	TMCO6	interactor	2	1.000	0	Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat IBB (PF01749, IPR002652): Importin beta binding domain KorB (PF08535, IPR013741): KorB domain HEAT_EZ (PF13513): HEAT-like repeat
173	TMEM31	interactor	1	0	0	DUF912 (PF06024, IPR009261): Nucleopolyhedrovirus protein of unknown function (DUF912) DUF2207 (PF09972, IPR018702): Predicted membrane protein (DUF2207) DUF4519 (PF15012, IPR027960): Domain of unknown function (DUF4519)
174	TMEM37	interactor	1	0	0	TMEM37 (PF15108, IPR029372): Voltage-dependent calcium channel gamma-like subunit protein family
175	TMUB2	interactor	1	0	0	SKG6 (PF08693, IPR014805): Transmembrane alpha-helix domain ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
176	TNFRSF1A	oncoprotein	5	0.500	3.000	Death (PF00531, IPR000488, SM00005): Death domain TNFR_c6 (PF00020, IPR001368, SM00208): TNFR/NGFR cysteine-rich region
177	TNFRSF1B	oncoprotein	3	1.000	0	TNFR_c6 (PF00020, IPR001368, SM00208): TNFR/NGFR cysteine-rich region
178	TREX1	interactor	1	0	0	RNase_T (PF00929, IPR013520): Exonuclease DUF2733 (PF10813, IPR024360): Protein of unknown function (DUF2733) PRIMA1 (PF16101): Proline-rich membrane anchor 1
179	TRIAP1	oncoprotein	1	0	0	UPF0203 (PF05254, IPR007918): Uncharacterised protein family (UPF0203)
180	TRIM32	suppressor	10	0.389	15.621	NHL (PF01436, IPR001258): NHL repeat zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger Zn_Tnp_IS1595 (PF12760, IPR024442): Transposase zinc-ribbon domain zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1
181	TXNDC12	interactor	1	0	0	Thioredoxin_7 (PF13899): Thioredoxin-like
182	UBB	interactor	11	0.291	23.505	ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
183	UBC	protein found in more fusions	47	0.221	506.417	ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
184	UBE2A	interactor	10	0.611	3.721	UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
185	UBE2B	interactor	13	0.606	6.588	UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
186	UBE2C	oncoprotein	20	0.444	48.570	UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
187	UBE2D1	interactor	21	0.347	62.065	UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
188	UBE2D2	oncoprotein	18	0.375	45.537	UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
189	UBE2V1	interactor	15	0.467	24.431	UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
190	UBE3A	oncoprotein	20	0.386	61.665	HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase) PCM1_C (PF15717, IPR031446): Pericentriolar material 1 C terminus AZUL (PF16558, IPR032353): Amino-terminal Zinc-binding domain of ubiquitin ligase E3A
191	UBE4B	suppressor	21	0.421	47.095	DUF1180 (PF06679, IPR009565): Protein of unknown function (DUF1180) NUDE_C (PF04880, IPR006964): NUDE protein, C-terminal conserved region Ufd2P_core (PF10408, IPR019474): Ubiquitin elongating factor core U-box (PF04564, IPR003613, SM00504): U-box domain DUF4568 (PF15132, IPR027919): Domain of unknown function (DUF4568)
192	UBL4A	interactor	15	0.295	42.777	ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
193	UBL7	oncoprotein	13	0.603	12.783	UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
194	UBQLN2	protein found in more fusions	33	0.206	271.675	Clathrin-link (PF09268, IPR015348): Clathrin, heavy-chain linker Collagen (PF01391, IPR008160): Collagen triple helix repeat (20 copies) TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain XPC-binding (PF09280, IPR015360): XPC-binding domain ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family SUZ (PF12752, IPR024771): SUZ domain Fur_reg_FbpB (PF13040, IPR025004): Fur-regulated basic protein B
195	UBQLN4	interactor	66	0.065	1790.347	CRF (PF00473, IPR000187, SM00039): Corticotropin-releasing factor family DUF1180 (PF06679, IPR009565): Protein of unknown function (DUF1180) Arm_2 (PF04826, IPR006911): Armadillo-like NUDE_C (PF04880, IPR006964): NUDE protein, C-terminal conserved region UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain XPC-binding (PF09280, IPR015360): XPC-binding domain ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family Fur_reg_FbpB (PF13040, IPR025004): Fur-regulated basic protein B partial_CstF (PF15861, IPR031721): Partial cleavage stimulation factor domain
196	UBXN1	interactor	19	0.392	51.566	Selenoprotein_S (PF06936, IPR009703): Selenoprotein S (SelS) UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain UBX (PF00789, IPR001012, SM00166): UBX domain
197	UBXN4	interactor	3	1.000	0	Asp-B-Hydro_N (PF05279, IPR007943): Aspartyl beta-hydroxylase N-terminal region Bap31 (PF05529, IPR008417): B-cell receptor-associated protein 31-like UBX (PF00789, IPR001012, SM00166): UBX domain Thioredoxin_7 (PF13899): Thioredoxin-like
198	UCHL3	interactor	15	0.505	22.465	Peptidase_C12 (PF01088, IPR001578): Ubiquitin carboxyl-terminal hydrolase, family 1
199	UNK	interactor	15	0.352	40.126	MbeD_MobD (PF04899, IPR006983): MbeD/MobD like NUDE_C (PF04880, IPR006964): NUDE protein, C-terminal conserved region zf-CCCH (PF00642, IPR000571): Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF3450 (PF11932, IPR016866): Protein of unknown function (DUF3450) zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger) zf-CCCH_2 (PF14608): RNA-binding, Nab2-type zinc finger Torus (PF16131, IPR032297): Torus domain
200	USP34	interactor	17	0.581	16.981	Secretin_N_2 (PF07655, IPR011514): Secretin N-terminal domain UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase DUF3517 (PF12030, IPR021905): Domain of unknown function (DUF3517)
201	USP9X	interactor	17	0.529	26.759	DUF1722 (PF08349, IPR013560): Protein of unknown function (DUF1722) UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase Utp13 (PF08625, IPR013934): Utp13 specific WD40 associated domain
202	VCP	protein found in more fusions	33	0.190	298.259	AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA) CDC48_2 (PF02933, IPR004201, SM01072): Cell division protein 48 (CDC48), domain 2 CDC48_N (PF02359, IPR003338, SM01073): Cell division protein 48 (CDC48), N-terminal domain TniB (PF05621, IPR008868): Bacterial TniB protein Vps4_C (PF09336, IPR015415): Vps4 C terminal oligomerisation domain DUF3944 (PF13099, IPR025217): Domain of unknown function (DUF3944)
203	VPS26A	protein found in more fusions	14	0.295	32.167	Vps26 (PF03643, IPR005377): Vacuolar protein sorting-associated protein 26
204	VPS4B	interactor	9	0.667	7.764	AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA) AAA_2 (PF07724, IPR013093): AAA domain (Cdc48 subfamily) MIT (PF04212, IPR007330, SM00745): MIT (microtubule interacting and transport) domain MMR_HSR1 (PF01926, IPR006073): 50S ribosome-binding GTPase TIP49 (PF06068, IPR010339): TIP49 C-terminus Vps4_C (PF09336, IPR015415): Vps4 C terminal oligomerisation domain
205	WDFY1	interactor	1	0	0	FYVE (PF01363, IPR000306, SM00064): FYVE zinc finger WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain ELYS-bb (PF16687, IPR032040): beta-propeller of ELYS nucleoporin
206	XPO4	interactor	3	0.667	0.667	CRM1_C (PF08767, IPR014877, SM01102): CRM1 C terminal
207	ZFAND2B	interactor	7	0.571	3.625	UIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif zf-AN1 (PF01428, IPR000058, SM00154): AN1-like Zinc finger
208	ZG16	interactor	2	1.000	0	Jacalin (PF01419, IPR001229, SM00915): Jacalin-like lectin domain Beta-prism_lec (PF16458, IPR032496): Beta-prism lectin
209	ZG16B	interactor	3	1.000	0	Jacalin (PF01419, IPR001229, SM00915): Jacalin-like lectin domain
210	ZMYM3	interactor	3	0.667	0.286	NCD3G (PF07562, IPR011500): Nine Cysteines Domain of family 3 GPCR YHS (PF04945, IPR007029): YHS domain zf-FCS (PF06467, IPR010507): MYM-type Zinc finger with FCS sequence motif DUF3504 (PF12012, IPR021893): Domain of unknown function (DUF3504) SOBP (PF15279, IPR026092): Sine oculis-binding protein
211	ZMYM4	interactor	1	0	0	YHS (PF04945, IPR007029): YHS domain DUF2116 (PF09889, IPR019216): Uncharacterized protein containing a Zn-ribbon (DUF2116) zf-FCS (PF06467, IPR010507): MYM-type Zinc finger with FCS sequence motif DUF3504 (PF12012, IPR021893): Domain of unknown function (DUF3504) zinc_ribbon_4 (PF13717): zinc-ribbon domain YyzF (PF14116, IPR025626): YyzF-like protein
212	ZNF343	interactor	2	1.000	0	KRAB (PF01352, IPR001909, SM00349): KRAB box zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-P11 (PF03854, IPR003224): P-11 zinc finger zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_4 (PF13894): C2H2-type zinc finger
213	ZRANB2	interactor	13	0.513	23.277	RRN3 (PF05327, IPR007991): RNA polymerase I specific transcription initiation factor RRN3 zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others

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