Find Fusion Network

Visualization interactions

Powered by Cytoscape Web for: parental proteins UBE2N (from a repository: Sun Dec 4 11:52:45 2016)

Examples AFF1 MLL ACTN4 + MLLAFF1 + MLLALK + MSNALK + TFGALK + TPM3ALK + TPM4ASXL2 + KAT6AATF1 + FUSBCR + ABL1BCR + FGFR1CCND1 + TACSTD2CD74 + ROS1CDK6 + MLLCOL1A1 + PDGFBCREB3L2 + PPARGCREB3L2 + FUSCREBBP + KAT6ADAZAP1 + MEF2DELL + MLLEPS15 + MLLERG + EWSR1ERG + FUSERG + TMPRSS2ETV5 + TMPRSS2ETV6 + ABL1ETV6 + NTRK3ETV6 + PAX5EWSR1 + FLI1EWSR1 + WT1FOXO1 + PAX3FOXP1 + PAX5FRYL + MLLGAS7 + MLLGMPS + MLLGOLGA5 + RETHOOK3 + RETHOXC13 + NUP98HOXD13 + NUP98MECOM + RUNX1MKL1 + RBM15MLL + MLLT1MLL + MLLT4MLL + MLLT10MLL + PICALMMLLT10 + PICALMNCOA1 + PAX3NIN + PDGFRBNPM1 + RARANRG1 + ODZ4NTRK1 + TFGNUMA1 + RARANUP98 + PHF23PAX5 + ZNF521PBX1 + TCF3RET + TRIM27ROS1 + SLC34A2PML + RARAPRKAR1A + RARAPRKAR1A + RETRUNX1 + RUNX1T1RUNX1 + SH3D19	Cytoscape Web will replace the contents your graph	PPI Properties: Click on nodes or edges
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Statistics and Network structure information

Statistic of PPI Value(s) The number of interactors (fusion and proteins) 153 The number (and %) of the onco-proteins 40 (26.14 %) The number (and %) of the tumor suppressors 23 (15.03 %) Total number of binary PPIs (saturation %) 733 (6.30 %) The number (and %) of affected PPIs 153 (20.87 %) The number of possible different fusions 33 PPI diameter 2 PPI radius 1 The average degree of PPI 8.497 Assortativity coefficient -0.3239 The network average Clustering coefficient 0.552 The number (and %) of a zero Clustering coefficients 15 (9.80 %) The number (and %) of a zero Betweenness Centrality 44 (28.76 %)

ACTIVE INTERACTORS

List of the fusions
PPI for parental proteins: UBE2N	All fusions : AI031822;
Proteins found in more fusions	ARIH1 (see 4 fusions); TRAF6 (see 1 fusions); RNF11 (see 1 fusions); TNF (see 1 fusions); HSP90AA1 (see 2 fusions); TRIM25 (see 2 fusions); GNPNAT1 (see 1 fusions); TRIM28 (see 1 fusions); TRIM33 (see 1 fusions); TRIM27/MDM2 (see 1 fusions); SIAH1 (see 4 fusions); RNF168 (see 2 fusions); UBE2N (see 1 fusions); UBA1 (see 2 fusions); ZNRF1 (see 1 fusions); NEDD4L (see 3 fusions); MALT1 (see 1 fusions); RNF111 (see 1 fusions); ARIH2 (see 2 fusions); SF1 (see 1 fusions); SH3RF1 (see 1 fusions); BAG3 (see 4 fusions); RIPK1 (see 1 fusions); STUB1 (see 1 fusions); MYLIP (see 1 fusions); PJA2 (see 1 fusions); HSPB1 (see 4 fusions); UBC (see 1 fusions); MFN2 (see 2 fusions); MIB1 (see 3 fusions); TP53 (see 3 fusions); SNW1 (see 1 fusions);

List of active interactors

#	Name	Type	Number of PPI (degree)	Clustering Coefficient	Betweenness Centrality	Domains (Pfam, InterPro, SMART): description
1	UBE2N	parental protein	153	0.043	17457.646	UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
2	ACACA	interactor	4	0.500	1.122	ACC_central (PF08326, IPR013537): Acetyl-CoA carboxylase, central region Biotin_carb_C (PF02785, IPR005482, SM00878): Biotin carboxylase C-terminal domain Biotin_lipoyl (PF00364, IPR000089): Biotin-requiring enzyme Carboxyl_trans (PF01039, IPR000022): Carboxyl transferase domain Biotin_carb_N (PF00289, IPR005481): Biotin carboxylase, N-terminal domain CPSase_L_D2 (PF02786, IPR005479): Carbamoyl-phosphate synthase L chain, ATP binding domain DUF445 (PF04286, IPR007383): Protein of unknown function (DUF445)
3	ACOT13	interactor	4	0.667	0.286	4HBT (PF03061, IPR006683): Thioesterase superfamily DUF4442 (PF14539, IPR027961): Domain of unknown function (DUF4442)
4	ACTR2	interactor	7	0.619	2.142	Actin (PF00022, IPR004000, SM00268): Actin
5	AMFR	oncoprotein	9	0.429	9.250	CUE (PF02845, IPR003892, SM00546): CUE domain UbiA (PF01040, IPR000537): UbiA prenyltransferase family zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain
6	ARF4	interactor	8	0.393	13.567	Arf (PF00025, IPR006689, SM00177): ADP-ribosylation factor family
7	ARIH1	protein found in more fusions	4	0.667	0.333	CENP-B_dimeris (PF09026, IPR015115): Centromere protein B dimerisation domain IBR (PF01485, IPR002867, SM00647): IBR domain, a half RING-finger domain Med14 (PF08638, IPR013947): Mediator complex subunit MED14 zinc_ribbon_2 (PF13240, IPR026870): zinc-ribbon domain zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger) zf-RING_4 (PF14570): RING/Ubox like zinc-binding domain
8	ARIH2	protein found in more fusions	7	0.800	1.019	IBR (PF01485, IPR002867, SM00647): IBR domain, a half RING-finger domain zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger) zinc_ribbon_12 (PF11331, IPR021480): Probable zinc-ribbon domain zf-C3HC4_4 (PF15227): zinc finger of C3HC4-type, RING PRAS (PF15798, IPR026682): Proline-rich AKT1 substrate 1
9	ASPDH	interactor	2	1.000	0	DUF108 (PF01958, IPR002811): Domain of unknown function DUF108 NAD_binding_3 (PF03447, IPR005106): Homoserine dehydrogenase, NAD binding domain
10	ATP2B3	interactor	2	1.000	0	Cation_ATPase_C (PF00689, IPR006068): Cation transporting ATPase, C-terminus Cation_ATPase_N (PF00690, IPR004014, SM00831): Cation transporter/ATPase, N-terminus E1-E2_ATPase (PF00122, IPR008250): E1-E2 ATPase Hydrolase_3 (PF08282, IPR023214): haloacid dehalogenase-like hydrolase ATP_Ca_trans_C (PF12424, IPR022141): Plasma membrane calcium transporter ATPase C terminal Cation_ATPase (PF13246): Cation transport ATPase (P-type)
11	ATP6V1H	interactor	1	0	0	V-ATPase_H_N (PF03224, IPR004908): V-ATPase subunit H V-ATPase_H_C (PF11698, IPR011987): V-ATPase subunit H
12	AURKA	oncoprotein	14	0.359	27.532	Pkinase (PF00069, IPR000719): Protein kinase domain MTBP_C (PF14920, IPR029418): MDM2-binding
13	BAG3	oncoprotein	8	0.667	3.000	BAG (PF02179, IPR003103, SM00264): BAG domain WW (PF00397, IPR001202, SM00456): WW domain
14	BARD1	suppressor	10	0.500	8.036	BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_5 (PF13857): Ankyrin repeats (many copies) zf-RING_6 (PF14835): zf-RING of BARD1-type protein BRCT_2 (PF16589, IPR001357): BRCT domain, a BRCA1 C-terminus domain
15	BCL10	suppressor	14	0.372	32.716	CARD (PF00619, IPR001315, SM00114): Caspase recruitment domain
16	BFAR	interactor	3	1.000	0	SAM_1 (PF00536, IPR021129, SM00454): SAM domain (Sterile alpha motif) DUF2231 (PF09990, IPR019251): Predicted membrane protein (DUF2231) zf-C3HC4_4 (PF15227): zinc finger of C3HC4-type, RING
17	BIRC3	oncoprotein	15	0.484	22.390	BIR (PF00653, IPR001370, SM00238): Inhibitor of Apoptosis domain CARD (PF00619, IPR001315, SM00114): Caspase recruitment domain zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
18	BIRC8	interactor	4	0.833	0.286	BIR (PF00653, IPR001370, SM00238): Inhibitor of Apoptosis domain zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
19	BRCA1	suppressor	18	0.250	71.925	BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger) BRCT_assoc (PF12820, IPR025994): Serine-rich domain associated with BRCT
20	CAB39	interactor	4	0.500	3.000	Mo25 (PF08569, IPR013878): Mo25-like
21	CADPS2	oncoprotein	1	0	0	DUF1041 (PF06292, IPR010439, SM01145): Domain of Unknown Function (DUF1041) PH (PF00169, IPR001849, SM00233): PH domain
22	CDC5L	interactor	14	0.346	32.508	OmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like) Pox_A_type_inc (PF04508, IPR007596): Viral A-type inclusion protein repeat Cir_N (PF10197, IPR019339, SM01083): N-terminal domain of CBF1 interacting co-repressor CIR Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain Myb_Cef (PF11831, IPR021786): pre-mRNA splicing factor component Myb_DNA-bind_6 (PF13921): Myb-like DNA-binding domain
23	CDK2	suppressor	15	0.308	42.624	Kdo (PF06293, IPR010440): Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase (PF00069, IPR000719): Protein kinase domain
24	CHFR	suppressor	5	0.500	1.833	FHA (PF00498, IPR000253, SM00240): FHA domain Glyco_hydro_92 (PF07971, IPR012939): Glycosyl hydrolase family 92 zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger) zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger) LAX (PF15681, IPR031393): Lymphocyte activation family X
25	CHUK	suppressor	15	0.473	22.904	Pkinase (PF00069, IPR000719): Protein kinase domain IKKbetaNEMObind (PF12179, IPR022007): I-kappa-kinase-beta NEMO binding domain
26	CNEP1R1	interactor	2	1.000	0	Tmemb_18A (PF09771, IPR019168): Transmembrane protein 188
27	CNOT4	interactor	3	1.000	0	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RING_4 (PF14570): RING/Ubox like zinc-binding domain Nup35_RRM_2 (PF14605): Nup53/35/40-type RNA recognition motif zf-CCCH_2 (PF14608): RNA-binding, Nab2-type zinc finger
28	DTL	interactor	5	0.600	3.000	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
29	DTX1	interactor	2	0	0	WWE (PF02825, IPR004170, SM00678): WWE domain zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger) zf-UDP (PF14569, IPR027934): Zinc-binding RING-finger PRIMA1 (PF16101): Proline-rich membrane anchor 1
30	DZIP3	interactor	6	0.700	0.806	DUF16 (PF01519, IPR002862): Protein of unknown function DUF16 SlyX (PF04102, IPR007236): SlyX zf-RING-like (PF08746, IPR014857): RING-like domain zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain BST2 (PF16716, IPR024886): Bone marrow stromal antigen 2 PKcGMP_CC (PF16808, IPR031831): Coiled-coil N-terminus of cGMP-dependent protein kinase
31	ELAVL1	oncoprotein	40	0.092	567.828	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
32	EPM2A	interactor	6	0.600	2.667	CBM_20 (PF00686, IPR002044): Starch binding domain DSPc (PF00782, IPR020422, SM00195): Dual specificity phosphatase, catalytic domain
33	F12	interactor	2	0	0	EGF (PF00008, IPR000742, SM00181): EGF-like domain fn1 (PF00039, IPR000083, SM00058): Fibronectin type I domain fn2 (PF00040, IPR000562, SM00059): Fibronectin type II domain Kringle (PF00051, IPR000001): Kringle domain Trypsin (PF00089, IPR001254, SM00020): Trypsin
34	FH	suppressor	6	0.467	7.667	Lyase_1 (PF00206, IPR022761): Lyase FumaraseC_C (PF10415, IPR018951): Fumarase C C-terminus
35	FN1	oncoprotein	16	0.208	59.678	fn1 (PF00039, IPR000083, SM00058): Fibronectin type I domain fn2 (PF00040, IPR000562, SM00059): Fibronectin type II domain fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369)
36	GNPNAT1	protein found in more fusions	4	0.667	1.000	Acetyltransf_1 (PF00583, IPR000182): Acetyltransferase (GNAT) family
37	HADH	interactor	2	1.000	0	3HCDH (PF00725, IPR006108): 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 3HCDH_N (PF02737, IPR006176): 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Collagen (PF01391, IPR008160): Collagen triple helix repeat (20 copies) Pyr_redox_2 (PF07992, IPR023753): Pyridine nucleotide-disulphide oxidoreductase
38	HERC2	interactor	9	0.500	7.433	ANAPC10 (PF03256, IPR004939): Anaphase-promoting complex, subunit 10 (APC10) Cyt-b5 (PF00173, IPR001199, SM01117): Cytochrome b5-like Heme/Steroid binding domain MIB_HERC2 (PF06701, IPR010606): Mib_herc2 RCC1 (PF00415, IPR000408): Regulator of chromosome condensation (RCC1) repeat zf-UBR (PF02207, IPR003126): Putative zinc finger in N-recognin (UBR box) HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase) ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type Cul7 (PF11515, IPR021097): Mouse development and cellular proliferation protein Cullin-7 Med3 (PF11593, IPR020998): Mediator complex subunit 3 fungal RCC1_2 (PF13540): Regulator of chromosome condensation (RCC1) repeat
39	HLTF	suppressor	11	0.356	20.305	HIRAN (PF08797, IPR014905, SM00910): HIRAN domain SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
40	HNRNPA3	oncoprotein	6	0.533	2.175	IATP (PF04568, IPR007648): Mitochondrial ATPase inhibitor, IATP RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
41	HSP90AA1	oncoprotein	30	0.180	230.681	HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HSP90 (PF00183, IPR001404): Hsp90 protein
42	HSPB1	oncoprotein	19	0.294	72.069	HSP20 (PF00011, IPR002068): Hsp20/alpha crystallin family
43	IDH3A	interactor	1	0	0	Iso_dh (PF00180, IPR024084): Isocitrate/isopropylmalate dehydrogenase
44	IL1B	oncoprotein	2	1.000	0	IL1 (PF00340, IPR000975, SM00125): Interleukin-1 / 18 IL1_propep (PF02394, IPR003502): Interleukin-1 propeptide
45	ISG15	suppressor	8	0.464	8.508	ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
46	KIF1C	interactor	1	0	0	FHA (PF00498, IPR000253, SM00240): FHA domain IncA (PF04156, IPR007285): IncA protein Kinesin (PF00225, IPR001752, SM00129): Kinesin motor domain Kinesin_assoc (PF16183, IPR032405): Kinesin-associated
47	LDHAL6A	interactor	3	1.000	0	Ldh_1_C (PF02866, IPR022383): lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N (PF00056, IPR001236): lactate/malate dehydrogenase, NAD binding domain
48	LDHB	interactor	10	0.417	13.906	Ldh_1_C (PF02866, IPR022383): lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N (PF00056, IPR001236): lactate/malate dehydrogenase, NAD binding domain
49	LDHC	interactor	3	0.667	0.667	Ldh_1_C (PF02866, IPR022383): lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N (PF00056, IPR001236): lactate/malate dehydrogenase, NAD binding domain
50	LGALS1	interactor	4	0.500	1.154	Gal-bind_lectin (PF00337, IPR001079, SM00908): Galactoside-binding lectin
51	LRSAM1	interactor	7	0.600	3.367	Baculo_PEP_C (PF04513, IPR007601): Baculovirus polyhedron envelope protein, PEP, C terminus SAM_1 (PF00536, IPR021129, SM00454): SAM domain (Sterile alpha motif) SAM_2 (PF07647, IPR011510): SAM domain (Sterile alpha motif) LRR_8 (PF13855, IPR001611): Leucine rich repeat zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
52	MALT1	oncoprotein	9	0.679	2.999	Peptidase_C14 (PF00656, IPR011600): Caspase domain V-set (PF07686, IPR013106): Immunoglobulin V-set domain Ig_2 (PF13895, IPR007110): Immunoglobulin domain Ig_3 (PF13927): Immunoglobulin domain
53	MARCH5	interactor	5	0.667	1.286	DUF2517 (PF10725, IPR019663): Protein of unknown function (DUF2517) RINGv (PF12906, IPR011016, SM00744): RING-variant domain
54	MARCH7	interactor	5	1.000	0	RINGv (PF12906, IPR011016, SM00744): RING-variant domain
55	MDM2	oncoprotein	19	0.275	73.544	Pinin_SDK_N (PF04697, IPR006787): pinin/SDK conserved region Presenilin (PF01080, IPR001108): Presenilin SWIB (PF02201, IPR003121, SM00151): SWIB/MDM2 domain zf-FPG_IleRS (PF06827, IPR010663): Zinc finger found in FPG and IleRS zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
56	MFN2	protein found in more fusions	4	1.000	0	Apolipoprotein (PF01442, IPR000074): Apolipoprotein A1/A4/E domain Fzo_mitofusin (PF04799, IPR006884): fzo-like conserved region Dynamin_N (PF00350, IPR001401, SM00053): Dynamin family
57	MIB1	protein found in more fusions	3	1.000	0	Ank (PF00023, IPR002110, SM00248): Ankyrin repeat MIB_HERC2 (PF06701, IPR010606): Mib_herc2 ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_4 (PF13637): Ankyrin repeats (many copies) Ank_5 (PF13857): Ankyrin repeats (many copies) zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
58	MIB2	oncoprotein	2	1.000	0	Ank (PF00023, IPR002110, SM00248): Ankyrin repeat KOW (PF00467, IPR005824, SM00739): KOW motif MIB_HERC2 (PF06701, IPR010606): Mib_herc2 TPR_4 (PF07721, IPR011717): Tetratricopeptide repeat ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_4 (PF13637): Ankyrin repeats (many copies) Ank_5 (PF13857): Ankyrin repeats (many copies) zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
59	MID1	oncoprotein	9	0.429	6.751	Baculo_PEP_C (PF04513, IPR007601): Baculovirus polyhedron envelope protein, PEP, C terminus fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain SPRY (PF00622, IPR003877, SM00449): SPRY domain DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369) zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger PRY (PF13765, IPR006574, SM00589): SPRY-associated domain zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger zf-C3HC4_4 (PF15227): zinc finger of C3HC4-type, RING
60	MID2	interactor	7	0.533	3.000	fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain SPRY (PF00622, IPR003877, SM00449): SPRY domain zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger PRY (PF13765, IPR006574, SM00589): SPRY-associated domain zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger CEBP_ZZ (PF16366, IPR032296): Cytoplasmic polyadenylation element-binding protein ZZ domain APC_u15 (PF16636): Unstructured region on APC between APC_crr regions 5 and 6
61	MKRN3	oncoprotein	9	0.500	10.150	zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger) MKRN1_C (PF15815, IPR031644): E3 ubiquitin-protein ligase makorin-1, C-terminal Torus (PF16131, IPR032297): Torus domain zf-3CxxC_2 (PF17180): Zinc-binding domain
62	MYLIP	protein found in more fusions	2	0	0	FERM_C (PF09380, IPR018980): FERM C-terminal PH-like domain FERM_M (PF00373, IPR019748): FERM central domain FERM_N (PF09379, IPR018979): FERM N-terminal domain zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
63	NBN	suppressor	7	0.476	5.656	FHA (PF00498, IPR000253, SM00240): FHA domain Nbs1_C (PF08599, IPR013908): DNA damage repair protein Nbs1 NIBRIN_BRCT_II (PF16508, IPR032429): Second BRCT domain on Nijmegen syndrome breakage protein RTT107_BRCT_5 (PF16770, IPR001357): Regulator of Ty1 transposition protein 107 BRCT domain
64	NEDD4L	suppressor	6	0.600	1.683	WW (PF00397, IPR001202, SM00456): WW domain HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
65	NEURL1	suppressor	2	1.000	0	Neuralized (PF07177, IPR006573, SM00588): Neuralized zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
66	NFX1	interactor	1	0	0	R3H (PF01424, IPR001374, SM00393): R3H domain XPG_I (PF00867, IPR006086, SM00484): XPG I-region zf-NF-X1 (PF01422, IPR000967, SM00438): NF-X1 type zinc finger
67	NHLRC1	interactor	5	0.833	0.667	NHL (PF01436, IPR001258): NHL repeat zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger zf-RING_5 (PF14634, IPR001841): zinc-RING finger domain
68	OTUB1	interactor	13	0.346	34.280	Peptidase_C65 (PF10275, IPR019400): Peptidase C65 Otubain
69	OTUB2	interactor	12	0.364	27.067	Peptidase_C65 (PF10275, IPR019400): Peptidase C65 Otubain
70	PARK2	suppressor	19	0.242	92.499	IBR (PF01485, IPR002867, SM00647): IBR domain, a half RING-finger domain ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
71	PC	interactor	1	0	0	Biotin_carb_C (PF02785, IPR005482, SM00878): Biotin carboxylase C-terminal domain Biotin_lipoyl (PF00364, IPR000089): Biotin-requiring enzyme Biotin_carb_N (PF00289, IPR005481): Biotin carboxylase, N-terminal domain CPSase_L_D2 (PF02786, IPR005479): Carbamoyl-phosphate synthase L chain, ATP binding domain HMGL-like (PF00682, IPR000891): HMGL-like PYC_OADA (PF02436, IPR003379): Conserved carboxylase domain
72	PCCA	interactor	3	1.000	0	Biotin_carb_C (PF02785, IPR005482, SM00878): Biotin carboxylase C-terminal domain Biotin_lipoyl (PF00364, IPR000089): Biotin-requiring enzyme Biotin_carb_N (PF00289, IPR005481): Biotin carboxylase, N-terminal domain CPSase_L_D2 (PF02786, IPR005479): Carbamoyl-phosphate synthase L chain, ATP binding domain SLT_beta (PF02258, IPR003189): Shiga-like toxin beta subunit
73	PCCB	interactor	3	1.000	0	Carboxyl_trans (PF01039, IPR000022): Carboxyl transferase domain
74	PELI1	interactor	5	0.800	0.556	Pellino (PF04710, IPR006800): Pellino
75	PELI3	interactor	4	1.000	0	Pellino (PF04710, IPR006800): Pellino
76	PHGDH	interactor	11	0.345	20.021	2-Hacid_dh_C (PF02826, IPR006140): D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
77	PJA2	protein found in more fusions	3	1.000	0	zf-Di19 (PF05605, IPR008598): Drought induced 19 protein (Di19), zinc-binding Rad50_zn_hook (PF04423, IPR007517): Rad50 zinc hook motif zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain
78	PPIA	interactor	8	0.500	7.040	Pro_isomerase (PF00160, IPR002130): Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD
79	RAD23A	oncoprotein	14	0.372	27.962	UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain XPC-binding (PF09280, IPR015360): XPC-binding domain ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
80	RAD23B	suppressor	11	0.436	14.910	K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain XPC-binding (PF09280, IPR015360): XPC-binding domain ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family DUF3123 (PF11321, IPR021470): Protein of unknown function (DUF3123)
81	RBCK1	interactor	15	0.407	28.961	GAGA (PF09237, IPR015318): GAGA factor IBR (PF01485, IPR002867, SM00647): IBR domain, a half RING-finger domain ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger
82	RC3H1	interactor	4	0.667	0.900	PaaA_PaaC (PF05138, IPR007814): Phenylacetic acid catabolic protein zf-CCCH (PF00642, IPR000571): Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger Prok-RING_4 (PF14447): Prokaryotic RING finger family 4
83	RC3H2	interactor	7	0.667	1.219	Xin (PF08043, IPR012510): Xin repeat zf-CCCH (PF00642, IPR000571): Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger
84	RFWD3	interactor	5	0.800	0.667	OmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like) zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain zf-rbx1 (PF12678, IPR024766): RING-H2 zinc finger domain ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
85	RHNO1	interactor	2	1.000	0	RHINO (PF15319, IPR029293): RAD9, RAD1, HUS1-interacting nuclear orphan protein
86	RIPK1	protein found in more fusions	14	0.487	19.011	Death (PF00531, IPR000488, SM00005): Death domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase RHIM (PF12721, IPR025735): RIP homotypic interaction motif
87	RNF103	interactor	1	0	0	VWC (PF00093, IPR001007, SM00214): von Willebrand factor type C domain zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain
88	RNF11	protein found in more fusions	9	0.500	8.233	zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain zf-ANAPC11 (PF12861, IPR024991): Anaphase-promoting complex subunit 11 RING-H2 finger
89	RNF111	suppressor	8	0.619	3.818	zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain Prok-RING_1 (PF14446): Prokaryotic RING finger family 1 RNF111_N (PF15303, IPR029306): E3 ubiquitin-protein ligase Arkadia N-terminus
90	RNF115	interactor	6	0.600	1.600	Rad50_zn_hook (PF04423, IPR007517): Rad50 zinc hook motif zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain zinc_ribbon_9 (PF14369): zinc-ribbon
91	RNF122	interactor	3	1.000	0	zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain Prok-RING_1 (PF14446): Prokaryotic RING finger family 1 zf-RING_5 (PF14634, IPR001841): zinc-RING finger domain
92	RNF125	interactor	6	0.700	2.333	zf-Di19 (PF05605, IPR008598): Drought induced 19 protein (Di19), zinc-binding Rad50_zn_hook (PF04423, IPR007517): Rad50 zinc hook motif zf-C2H2_4 (PF13894): C2H2-type zinc finger zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
93	RNF126	interactor	7	0.533	4.400	Rad50_zn_hook (PF04423, IPR007517): Rad50 zinc hook motif zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger zinc_ribbon_9 (PF14369): zinc-ribbon
94	RNF128	interactor	4	1.000	0	CcmD (PF04995, IPR007078): Heme exporter protein D (CcmD) PA (PF02225, IPR003137): PA domain zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain
95	RNF13	interactor	1	0	0	DNA_ligase_ZBD (PF03119, IPR004149): NAD-dependent DNA ligase C4 zinc finger domain PA (PF02225, IPR003137): PA domain zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain FAM176 (PF14851): FAM176 family STAC2_u1 (PF16664): Unstructured on SH3 and cysteine-rich domain-containing protein 2
96	RNF130	interactor	3	0.667	0.333	PA (PF02225, IPR003137): PA domain PspB (PF06667, IPR009554): Phage shock protein B zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger Prok-RING_1 (PF14446): Prokaryotic RING finger family 1
97	RNF152	interactor	1	0	0	VMA21 (PF09446, IPR019013): VMA21-like domain zf-RING_5 (PF14634, IPR001841): zinc-RING finger domain
98	RNF165	interactor	2	1.000	0	zf-P11 (PF03854, IPR003224): P-11 zinc finger zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain zf-RING_5 (PF14634, IPR001841): zinc-RING finger domain
99	RNF167	interactor	3	1.000	0	DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region PA (PF02225, IPR003137): PA domain zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain Glucos_trans_II (PF14264, IPR025686): Glucosyl transferase GtrII Prok-RING_1 (PF14446): Prokaryotic RING finger family 1
100	RNF168	protein found in more fusions	6	0.600	2.056	ATP-synt_E (PF05680, IPR008386): ATP synthase E chain DUF4407 (PF14362, IPR025519): Domain of unknown function (DUF4407) Prok-RING_4 (PF14447): Prokaryotic RING finger family 4
101	RNF181	interactor	5	0.667	0.622	AhpC-TSA (PF00578, IPR000866): AhpC/TSA family
102	RNF182	interactor	3	0.667	0.100	zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain
103	RNF4	interactor	5	0.833	0.333	Sgf11 (PF08209, IPR013246): Sgf11 (transcriptional regulation protein) zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain zf-UDP (PF14569, IPR027934): Zinc-binding RING-finger
104	RNF43	oncoprotein	3	1.000	0	IBR (PF01485, IPR002867, SM00647): IBR domain, a half RING-finger domain zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain
105	RNF5	interactor	7	0.733	1.619	zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
106	RNF8	suppressor	10	0.417	12.822	FHA (PF00498, IPR000253, SM00240): FHA domain Jnk-SapK_ap_N (PF09744, IPR019143): JNK_SAPK-associated protein-1 zf-C2H2_2 (PF12756, IPR015880): C2H2 type zinc-finger (2 copies) zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger) DUF4665 (PF15679, IPR031389): Domain of unknown function (DUF4665)
107	SARDH	interactor	1	0	0	DAO (PF01266, IPR006076): FAD dependent oxidoreductase GCV_T (PF01571, IPR006222): Aminomethyltransferase folate-binding domain GCV_T_C (PF08669, IPR013977): Glycine cleavage T-protein C-terminal barrel domain FAO_M (PF16350, IPR032503): FAD dependent oxidoreductase central domain
108	SF1	protein found in more fusions	7	0.333	9.154	UPF0181 (PF03701, IPR005371): Uncharacterised protein family (UPF0181) zf-CCHC (PF00098, IPR001878): Zinc knuckle KH_1 (PF00013, IPR004088, SM00322): KH domain RCDG1 (PF15725, IPR031457): Renal cancer differentiation gene 1 protein PRIMA1 (PF16101): Proline-rich membrane anchor 1 SF1-HH (PF16275, IPR032570): Splicing factor 1 helix-hairpin domain
109	SH3RF1	protein found in more fusions	4	0.667	1.000	zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger) SH3_1 (PF00018, IPR001452, SM00326): SH3 domain SH3_9 (PF14604, IPR001452): Variant SH3 domain
110	SH3RF2	interactor	4	0.500	2.286	SH3_2 (PF07653, IPR011511): Variant SH3 domain TUDOR (PF00567, IPR002999, SM00333): Tudor domain UPF0547 (PF10571, IPR018886): Uncharacterised protein family UPF0547 SH3_1 (PF00018, IPR001452, SM00326): SH3 domain zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger SH3_9 (PF14604, IPR001452): Variant SH3 domain
111	SHPRH	suppressor	4	0.833	0.667	SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain GIT1_C (PF12205, IPR022018): G protein-coupled receptor kinase-interacting protein 1 C term TPR_7 (PF13176, IPR019734): Tetratricopeptide repeat zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger
112	SIAH1	suppressor	8	0.429	7.686	Sina (PF03145, IPR018121): Seven in absentia protein family
113	SLC2A4	interactor	2	1.000	0	Sugar_tr (PF00083, IPR005828): Sugar (and other) transporter
114	SNW1	protein found in more fusions	15	0.330	34.441	SKIP_SNW (PF02731, IPR004015): SKIP/SNW domain PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term SIR4_SID (PF16991, IPR031556): Sir4 SID domain
115	STAMBPL1	interactor	4	0.833	0.500	CHDCT2 (PF08074, IPR012957): CHDCT2 (NUC038) domain USP8_dimer (PF08969, IPR015063): USP8 dimerisation domain JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease
116	STUB1	suppressor	20	0.368	67.359	U-box (PF04564, IPR003613, SM00504): U-box domain ANAPC3 (PF12895): Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 (PF13414, IPR011990): TPR repeat TPR_20 (PF14561): Tetratricopeptide repeat
117	TMEM189	interactor	4	0.667	0.500	MARVEL (PF01284, IPR008253): Membrane-associating domain TMEM189_B_dmain (PF10520, IPR019547): B domain of TMEM189, localisation domain
118	TMEM189-UBE2V1	interactor	3	0.667	0.250	MARVEL (PF01284, IPR008253): Membrane-associating domain UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme TMEM189_B_dmain (PF10520, IPR019547): B domain of TMEM189, localisation domain
119	TNF	oncoprotein	12	0.509	15.211	TNF (PF00229, IPR006052, SM00207): TNF(Tumour Necrosis Factor) family
120	TNFAIP3	suppressor	17	0.442	32.600	OTU (PF02338, IPR003323): OTU-like cysteine protease zf-A20 (PF01754, IPR002653, SM00259): A20-like zinc finger Thioredoxin_3 (PF13192, IPR012336): Thioredoxin domain
121	TOPORS	suppressor	5	0.700	2.000	Rad50_zn_hook (PF04423, IPR007517): Rad50 zinc hook motif Med19 (PF10278, IPR019403): Mediator of RNA pol II transcription subunit 19 PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
122	TP53	suppressor	32	0.217	251.612	DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region P53 (PF00870, IPR011615): P53 DNA-binding domain P53_tetramer (PF07710, IPR010991): P53 tetramerisation motif
123	TRAF2	interactor	18	0.515	25.982	MATH (PF00917, IPR002083, SM00061): MATH domain Sina (PF03145, IPR018121): Seven in absentia protein family SlyX (PF04102, IPR007236): SlyX zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger) zf-TRAF (PF02176, IPR001293): TRAF-type zinc finger TRAF_BIRC3_bd (PF16673, IPR032070): TNF receptor-associated factor BIRC3 binding domain zf-C3HC4_5 (PF17121, IPR001841): Zinc finger, C3HC4 type (RING finger)
124	TRAF6	protein found in more fusions	20	0.363	68.994	SlyX (PF04102, IPR007236): SlyX zf-TRAF (PF02176, IPR001293): TRAF-type zinc finger zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
125	TRIM11	interactor	4	0.667	0.400	ATP-synt_B (PF00430, IPR002146): ATP synthase B/B' CF(0) SPRY (PF00622, IPR003877, SM00449): SPRY domain zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger PRY (PF13765, IPR006574, SM00589): SPRY-associated domain zf-C3HC4_4 (PF15227): zinc finger of C3HC4-type, RING
126	TRIM17	interactor	6	0.533	3.684	NlpE (PF04170, IPR007298): NlpE N-terminal domain SPRY (PF00622, IPR003877, SM00449): SPRY domain zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger PRY (PF13765, IPR006574, SM00589): SPRY-associated domain zf-Nse (PF11789, IPR004181): Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 (PF15227): zinc finger of C3HC4-type, RING
127	TRIM25	protein found in more fusions	8	0.476	7.167	Fes1 (PF08609, IPR013918): Nucleotide exchange factor Fes1 Pox_Rif (PF03340, IPR005008): Poxvirus rifampicin resistance protein SPRY (PF00622, IPR003877, SM00449): SPRY domain zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger PRY (PF13765, IPR006574, SM00589): SPRY-associated domain zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger Prok-RING_4 (PF14447): Prokaryotic RING finger family 4
128	TRIM27	oncoprotein	15	0.341	44.650	IncA (PF04156, IPR007285): IncA protein SPRY (PF00622, IPR003877, SM00449): SPRY domain zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger PRY (PF13765, IPR006574, SM00589): SPRY-associated domain zf-C2H2_4 (PF13894): C2H2-type zinc finger zf-RING_5 (PF14634, IPR001841): zinc-RING finger domain zf-C3HC4_4 (PF15227): zinc finger of C3HC4-type, RING Lebercilin (PF15619, IPR028933): Ciliary protein causing Leber congenital amaurosis disease
129	TRIM28	protein found in more fusions	12	0.400	18.180	ASFV_J13L (PF05568, IPR008385): African swine fever virus J13L protein K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain PHD (PF00628, IPR019787, SM00249): PHD-finger FYVE_2 (PF02318, IPR010911): FYVE-type zinc finger zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger zf-RING_5 (PF14634, IPR001841): zinc-RING finger domain SKA2 (PF16740, IPR026762): Spindle and kinetochore-associated protein 2
130	TRIM32	suppressor	13	0.424	23.345	NHL (PF01436, IPR001258): NHL repeat zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger Zn_Tnp_IS1595 (PF12760, IPR024442): Transposase zinc-ribbon domain zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1
131	TRIM33	oncoprotein	3	1.000	0	PHD (PF00628, IPR019787, SM00249): PHD-finger Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein Siva (PF05458, IPR022773): Cd27 binding protein (Siva) Spectrin (PF00435, IPR002017): Spectrin repeat TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger Bromodomain (PF00439, IPR001487, SM00297): Bromodomain zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger
132	TRIM39	interactor	8	0.619	3.369	Exonuc_VII_L (PF02601, IPR020579): Exonuclease VII, large subunit Prim_Zn_Ribbon (PF08273, IPR013237, SM00778): Zinc-binding domain of primase-helicase SPRY (PF00622, IPR003877, SM00449): SPRY domain zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger PRY (PF13765, IPR006574, SM00589): SPRY-associated domain zf-C3HC4_4 (PF15227): zinc finger of C3HC4-type, RING
133	TRIM5	interactor	10	0.583	6.586	Baculo_IE-1 (PF05290, IPR007954): Baculovirus immediate-early protein (IE-0) Baculo_PEP_C (PF04513, IPR007601): Baculovirus polyhedron envelope protein, PEP, C terminus SPRY (PF00622, IPR003877, SM00449): SPRY domain zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger TMF_TATA_bd (PF12325, IPR022091): TATA element modulatory factor 1 TATA binding zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger
134	TRIM50	interactor	1	0	0	Trimer_CC (PF08954, IPR015049, SM01167): Trimerisation motif SPRY (PF00622, IPR003877, SM00449): SPRY domain Trm112p (PF03966, IPR005651): Trm112p-like protein zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger PRY (PF13765, IPR006574, SM00589): SPRY-associated domain zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger
135	TRIM72	interactor	2	1.000	0	HrpB7 (PF09486, IPR013392): Bacterial type III secretion protein (HrpB7) IBR (PF01485, IPR002867, SM00647): IBR domain, a half RING-finger domain SPRY (PF00622, IPR003877, SM00449): SPRY domain zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger PRY (PF13765, IPR006574, SM00589): SPRY-associated domain zf-C3HC4_4 (PF15227): zinc finger of C3HC4-type, RING
136	TXNDC17	interactor	2	1.000	0	DUF953 (PF06110, IPR010357): Eukaryotic protein of unknown function (DUF953) Glutaredoxin (PF00462, IPR002109): Glutaredoxin
137	UBA1	protein found in more fusions	14	0.321	33.372	ThiF (PF00899, IPR000594): ThiF family E1_UFD (PF09358, IPR018965, SM00985): Ubiquitin fold domain UBA_e1_thiolCys (PF10585, IPR019572): Ubiquitin-activating enzyme active site
138	UBC	protein found in more fusions	66	0.113	1471.105	ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
139	UBE2K	interactor	31	0.159	292.879	UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
140	UBE2V1	interactor	26	0.252	161.004	UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
141	UBE2V2	interactor	22	0.260	116.198	UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
142	UBL5	interactor	3	0.667	1.000	ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
143	UFD1L	interactor	6	0.600	4.167	UFD1 (PF03152, IPR004854): Ubiquitin fusion degradation protein UFD1
144	USP14	interactor	5	0.800	1.333	UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
145	VASP	interactor	6	0.500	1.261	ASD2 (PF08687, IPR014799): Apx/Shroom domain ASD2 CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal VASP_tetra (PF08776, IPR014885): VASP tetramerisation domain WH1 (PF00568, IPR000697, SM00461): WH1 domain
146	VCAM1	interactor	13	0.256	30.259	C2-set (PF05790, IPR008424): Immunoglobulin C2-set domain I-set (PF07679, IPR013098): Immunoglobulin I-set domain ig (PF00047, IPR013151, SM00409): Immunoglobulin domain V-set (PF07686, IPR013106): Immunoglobulin V-set domain Ig_3 (PF13927): Immunoglobulin domain
147	VPS33B	interactor	4	0.667	1.167	Sec1 (PF00995, IPR001619): Sec1 family
148	XIAP	interactor	17	0.417	36.073	BIR (PF00653, IPR001370, SM00238): Inhibitor of Apoptosis domain zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
149	ZDHHC5	interactor	2	1.000	0	7TMR-DISM_7TM (PF07695, IPR011623): 7TM diverse intracellular signalling zf-DHHC (PF01529, IPR001594): DHHC palmitoyltransferase
150	ZNRF1	protein found in more fusions	6	0.800	1.333	zf-Di19 (PF05605, IPR008598): Drought induced 19 protein (Di19), zinc-binding zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain RNF220 (PF15926, IPR031824): E3 ubiquitin-protein ligase RNF220
151	ZNRF2	interactor	4	0.667	1.100	zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain SelK_SelG (PF10961, IPR024491): Selenoprotein SelK_SelG RNF220 (PF15926, IPR031824): E3 ubiquitin-protein ligase RNF220
152	ZNRF3	interactor	2	1.000	0	PA (PF02225, IPR003137): PA domain SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain Cadherin_C_2 (PF16492, IPR032455): Cadherin cytoplasmic C-terminal zf-C3H2C3 (PF17122, IPR001841): Zinc-finger
153	ZNRF4	interactor	1	0	0	PA (PF02225, IPR003137): PA domain zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger

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