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Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)283
The number (and %) of the onco-proteins90 (31.80 %)
The number (and %) of the tumor suppressors38 (13.43 %)
Total number of binary PPIs (saturation %)2641 (6.62 %)
The number (and %) of affected PPIs313 (11.85 %)
The number of possible different fusions58
PPI diameter3
PPI radius2
The average degree of PPI17.873
Assortativity coefficient-0.1995
The network average Clustering coefficient0.416
The number (and %) of a zero Clustering coefficients11 (3.89 %)
The number (and %) of a zero Betweenness Centrality25 (8.83 %)

ACTIVE INTERACTORS


List of the fusions

PPI for parental proteins: TUBA1A,TUBA1B All fusions
Proteins found in more fusions SYK (see 1 fusions); RUVBL1 (see 1 fusions); LGALS3BP (see 2 fusions); PINK1 (see 3 fusions); PARK2 (see 1 fusions); LAMP2 (see 1 fusions); VHL (see 1 fusions); GAN (see 1 fusions); PAFAH1B1 (see 1 fusions); HDAC5 (see 1 fusions); SNW1 (see 1 fusions); CUL4A (see 4 fusions); HSP90AA1 (see 6 fusions); HSP90AA1/PSMA3 (see 1 fusions); HSP90AB1 (see 3 fusions); SRPK2 (see 1 fusions); OFD1 (see 5 fusions); ERBB3 (see 2 fusions); SNRNP200 (see 2 fusions); TUBA1B/TUBA1A (see 2 fusions); SHC1 (see 1 fusions); EZH2 (see 1 fusions); TUBA1B/TUBA1C (see 11 fusions); CDC37 (see 2 fusions); ERRFI1 (see 1 fusions); GAPDH (see 5 fusions); TUBG1 (see 1 fusions); STAU1 (see 2 fusions); CTNNB1/SMAD2 (see 1 fusions); CUL7 (see 2 fusions); CUL3 (see 1 fusions); B4GALT1 (see 2 fusions); MYC (see 2 fusions); SSX2IP (see 1 fusions); GAPDH/CDKN1A (see 1 fusions); MAPRE1 (see 1 fusions); PIK3R1 (see 1 fusions); SKI (see 1 fusions); HTT (see 1 fusions); VCL (see 2 fusions); PEX14 (see 1 fusions); UBC (see 7 fusions); LRRK2 (see 1 fusions); HSP90AA1/TUBB (see 1 fusions); TP53 (see 3 fusions); AP2M1 (see 4 fusions); SMAD2 (see 2 fusions); KPNB1 (see 2 fusions); ACTN1 (see 3 fusions); RPL5 (see 1 fusions); SQSTM1 (see 5 fusions); NCOA6 (see 1 fusions); SP1 (see 1 fusions); MAPT (see 1 fusions); NDEL1 (see 1 fusions); EGFR (see 2 fusions); MCM2 (see 1 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 TUBA1Aparental protein2080.05732933.315Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain
Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain
2 TUBA1Bparental protein1060.0868386.597Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain
Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain
3 A2Minteractor120.10978.631A2M (PF00207, IPR001599): Alpha-2-macroglobulin family
A2M_comp (PF07678, IPR011626): A-macroglobulin complement component
A2M_N (PF01835, IPR002890): MG2 domain
A2M_N_2 (PF07703, IPR011625): Alpha-2-macroglobulin family N-terminal region
A2M_recep (PF07677, IPR009048): A-macroglobulin receptor
MP (PF01107, IPR028919): Viral movement protein (MP)
SVA (PF05326, IPR007990): Seminal vesicle autoantigen (SVA)
Thiol-ester_cl (PF10569, IPR019565): Alpha-macro-globulin thiol-ester bond-forming region
4 AARSD1interactor40.5003.632tRNA-synt_2c (PF01411, IPR018164): tRNA synthetases class II (A)
tRNA_SAD (PF07973, IPR012947, SM00863): Threonyl and Alanyl tRNA synthetase second additional domain
5 ACTN1protein found in more fusions240.186225.902CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
Dak2 (PF02734, IPR004007, SM01120): DAK2 domain
EFhand_Ca_insen (PF08726, IPR014837): Ca2+ insensitive EF hand
Spectrin (PF00435, IPR002017): Spectrin repeat
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
Uds1 (PF15456, IPR029191): Up-regulated During Septation
6 AGO3interactor110.56414.859ArgoL1 (PF08699, IPR014811, SM01163): Argonaute linker 1 domain
PAZ (PF02170, IPR003100, SM00949): PAZ domain
Piwi (PF02171, IPR003165, SM00950): Piwi domain
ArgoN (PF16486, IPR032474): N-terminal domain of argonaute
ArgoMid (PF16487, IPR032473): Mid domain of argonaute
ArgoL2 (PF16488, IPR032472): Argonaute linker 2 domain
7 AGTRAPinteractor302.247AGTRAP (PF06396, IPR009436, SM00805): Angiotensin II, type I receptor-associated protein (AGTRAP)
8 ALDH1L2interactor21.0000Aldedh (PF00171, IPR015590): Aldehyde dehydrogenase family
Formyl_trans_C (PF02911, IPR005793): Formyl transferase, C-terminal domain
Formyl_trans_N (PF00551, IPR002376): Formyl transferase
PP-binding (PF00550, IPR009081): Phosphopantetheine attachment site
9 ALKBH3interactor100.28935.6212OG-FeII_Oxy_2 (PF13532, IPR027450): 2OG-Fe(II) oxygenase superfamily
10 AMBRA1interactor170.35359.391Acyl_CoA_thio (PF02551, IPR025652): Acyl-CoA thioesterase
eIF2A (PF08662, IPR013979): Eukaryotic translation initiation factor eIF2A
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Spt20 (PF12090, IPR021950): Spt20 family
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
11 ANTXR1interactor60.33336.749Ant_C (PF05586, IPR008399): Anthrax receptor C-terminus region
Anth_Ig (PF05587, IPR008400): Anthrax receptor extracellular domain
VWA (PF00092, IPR002035, SM00327): von Willebrand factor type A domain
12 ANXA7suppressor80.25027.512Annexin (PF00191, IPR018502, SM00335): Annexin
13 AP2M1protein found in more fusions250.446120.610Adap_comp_sub (PF00928, IPR008968): Adaptor complexes medium subunit family
Clat_adaptor_s (PF01217, IPR022775): Clathrin adaptor complex small chain
14 APBB2interactor60.53312.463PID (PF00640, IPR006020, SM00462): Phosphotyrosine interaction domain (PTB/PID)
WW (PF00397, IPR001202, SM00456): WW domain
15 ARMC6interactor90.44410.526Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
Mis14 (PF08641, IPR013950): Kinetochore protein Mis14 like
Atx10homo_assoc (PF09759, IPR019156): Spinocerebellar ataxia type 10 protein domain
16 ARRB2interactor270.342138.346Arrestin_C (PF02752, IPR011022, SM01017): Arrestin (or S-antigen), C-terminal domain
Arrestin_N (PF00339, IPR011021): Arrestin (or S-antigen), N-terminal domain
17 ASB17interactor70.4767.377HTH_Mga (PF08280, IPR013199): M protein trans-acting positive regulator (MGA) HTH domain
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
SOCS_box (PF07525, IPR001496): SOCS box
18 ASCL2interactor31.0000HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
19 ASPMoncoprotein60.20014.142CcmD (PF04995, IPR007078): Heme exporter protein D (CcmD)
CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif
RST (PF12174, IPR022003): RCD1-SRO-TAF4 (RST) plant domain
ASH (PF15780, IPR031549): Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin
20 ATP5Binteractor330.312216.803AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA)
ATP-synt_ab (PF00006, IPR000194): ATP synthase alpha/beta family, nucleotide-binding domain
ATP-synt_ab_N (PF02874, IPR004100): ATP synthase alpha/beta family, beta-barrel domain
NACHT (PF05729): NACHT domain
21 ATP6V1B2interactor90.5834.919ATP-synt_ab (PF00006, IPR000194): ATP synthase alpha/beta family, nucleotide-binding domain
ATP-synt_ab_N (PF02874, IPR004100): ATP synthase alpha/beta family, beta-barrel domain
DUF2481 (PF10654, IPR018916): Protein of unknown function (DUF2481)
22 ATXN3interactor120.38219.275Josephin (PF02099, IPR006155): Josephin
UIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif
SUIM_assoc (PF16619): Unstructured region C-term to UIM in Ataxin3
23 AURKBinteractor270.332127.996Pkinase (PF00069, IPR000719): Protein kinase domain
24 B4GALT1protein found in more fusions31.0000Glyco_transf_7C (PF02709, IPR027791): N-terminal domain of galactosyltransferase
Glyco_transf_7N (PF13733, IPR027995): N-terminal region of glycosyl transferase group 7
25 BTG1oncoprotein206.802BTG (PF07742, IPR002087, SM00099): BTG family
26 C8orf33interactor40.6672.965DUF4615 (PF15393, IPR029274): Domain of unknown function (DUF4615)
27 CBLsuppressor270.385233.538Cbl_N (PF02262, IPR003153): CBL proto-oncogene N-terminal domain 1
Cbl_N2 (PF02761, IPR014741): CBL proto-oncogene N-terminus, EF hand-like domain
Cbl_N3 (PF02762, IPR014742): CBL proto-oncogene N-terminus, SH2-like domain
UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
Prok-RING_4 (PF14447): Prokaryotic RING finger family 4
zf-RING_4 (PF14570): RING/Ubox like zinc-binding domain
28 CBWD1interactor70.28612.659cobW (PF02492, IPR003495): CobW/HypB/UreG, nucleotide-binding domain
CobW_C (PF07683, IPR011629, SM00833): Cobalamin synthesis protein cobW C-terminal domain
29 CCAR2suppressor180.26887.206DREPP (PF05558, IPR008469): DREPP plasma membrane polypeptide
IncA (PF04156, IPR007285): IncA protein
RNA_pol_Rpc4 (PF05132, IPR007811): RNA polymerase III RPC4
DBC1 (PF14443, IPR025954, SM01122): DBC1
S1-like (PF14444, IPR025223): S1-like
30 CCNJLinteractor21.0000Cyclin_C (PF02984, IPR004367): Cyclin, C-terminal domain
Cyclin_N (PF00134, IPR006671): Cyclin, N-terminal domain
31 CCT2interactor460.270368.240Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
32 CCT6Ainteractor410.226338.485Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
33 CD247interactor30.6671.163ITAM (PF02189, IPR003110, SM00077): Immunoreceptor tyrosine-based activation motif
TCR_zetazeta (PF11628, IPR021663): T-cell surface glycoprotein CD3 zeta chain
34 CD81interactor180.39048.139Tetraspannin (PF00335, IPR018499): Tetraspanin family
35 CDC20oncoprotein220.43351.815WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
36 CDC37protein found in more fusions300.278241.605CDC37_C (PF08564, IPR013873, SM01069): Cdc37 C terminal domain
CDC37_M (PF08565, IPR013874, SM01070): Cdc37 Hsp90 binding domain
CDC37_N (PF03234, IPR013855, SM01071): Cdc37 N terminal kinase binding
Rho_Binding (PF08912, IPR015008): Rho Binding
TMF_DNA_bd (PF12329, IPR022092): TATA element modulatory factor 1 DNA binding
37 CDC5Linteractor510.288516.564OmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like)
Pox_A_type_inc (PF04508, IPR007596): Viral A-type inclusion protein repeat
Cir_N (PF10197, IPR019339, SM01083): N-terminal domain of CBF1 interacting co-repressor CIR
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
Myb_Cef (PF11831, IPR021786): pre-mRNA splicing factor component
Myb_DNA-bind_6 (PF13921): Myb-like DNA-binding domain
38 CDK13interactor140.48437.952K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain
Pkinase (PF00069, IPR000719): Protein kinase domain
Macoilin (PF09726, IPR019130): Transmembrane protein
THRAP3_BCLAF1 (PF15440, IPR029199): THRAP3/BCLAF1 family
39 CDKN1Asuppressor230.324139.315CDI (PF02234, IPR003175): Cyclin-dependent kinase inhibitor
40 CDKN2Asuppressor170.55133.548Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
Ank_5 (PF13857): Ankyrin repeats (many copies)
41 CEP250interactor250.380133.139ACCA (PF03255, IPR001095): Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit
DASH_Dam1 (PF08653, IPR013962): DASH complex subunit Dam1
DivIC (PF04977, IPR007060): Septum formation initiator
DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664)
EHN (PF06441, IPR010497): Epoxide hydrolase N terminus
ERM (PF00769, IPR011259): Ezrin/radixin/moesin family
Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family
IncA (PF04156, IPR007285): IncA protein
Seryl_tRNA_N (PF02403, IPR015866): Seryl-tRNA synthetase N-terminal domain
SlyX (PF04102, IPR007236): SlyX
Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein
Syntaxin-6_N (PF09177, IPR015260): Syntaxin 6, N-terminal
TSC22 (PF01166, IPR000580): TSC-22/dip/bun family
CENP-F_leu_zip (PF10473, IPR019513): Leucine-rich repeats of kinetochore protein Cenp-F/LEK1
Endonuc_Holl (PF10107, IPR019287): Endonuclease related to archaeal Holliday junction resolvase
DUF2570 (PF10828, IPR022538): Protein of unknown function (DUF2570)
DGF-1_C (PF11040, IPR021053): Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus
DUF2968 (PF11180, IPR021350): Protein of unknown function (DUF2968)
DUF3450 (PF11932, IPR016866): Protein of unknown function (DUF3450)
DUF3915 (PF13054, IPR025026): Protein of unknown function (DUF3915)
DUF4404 (PF14357, IPR025516): Domain of unknown function (DUF4404)
DUF4472 (PF14739, IPR029329): Domain of unknown function (DUF4472)
Rootletin (PF15035): Ciliary rootlet component, centrosome cohesion
KAsynt_C_assoc (PF16197, IPR032821): Ketoacyl-synthetase C-terminal extension
HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1
42 CEP76interactor100.35631.257Transglut_core (PF01841, IPR002931, SM00460): Transglutaminase-like superfamily
CEP76-C2 (PF15627, IPR028926): CEP76 C2 domain
43 CHORDC1interactor80.6195.457CHORD (PF04968, IPR007051): CHORD
CS (PF04969, IPR007052): CS domain
44 CLIP1oncoprotein70.5715.770ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16)
CAP_GLY (PF01302, IPR000938, SM01052): CAP-Gly domain
CP12 (PF02672, IPR003823, SM01093): CP12 domain
DASH_Hsk3 (PF08227, IPR013183): DASH complex subunit Hsk3 like
DUF848 (PF05852, IPR008566): Gammaherpesvirus protein of unknown function (DUF848)
FlaC_arch (PF05377, IPR008039): Flagella accessory protein C (FlaC)
FliJ (PF02050, IPR012823): Flagellar FliJ protein
Lectin_N (PF03954, IPR005640): Hepatic lectin, N-terminal domain
SlyX (PF04102, IPR007236): SlyX
ApoO (PF09769, IPR019166): Apolipoprotein O
Ax_dynein_light (PF10211, IPR019347): Axonemal dynein light chain
ADIP (PF11559, IPR021622): Afadin- and alpha -actinin-Binding
TMF_DNA_bd (PF12329, IPR022092): TATA element modulatory factor 1 DNA binding
DUF4200 (PF13863, IPR025252): Domain of unknown function (DUF4200)
Leu_zip (PF15294): Leucine zipper
CLIP1_ZNF (PF16641, IPR032108): CLIP1 zinc knuckle
PKcGMP_CC (PF16808, IPR031831): Coiled-coil N-terminus of cGMP-dependent protein kinase
45 CRKoncoprotein230.48661.779SH2 (PF00017, IPR000980, SM00252): SH2 domain
SH3_2 (PF07653, IPR011511): Variant SH3 domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
46 CTDSP1interactor30.33311.930NIF (PF03031, IPR004274): NLI interacting factor-like phosphatase
47 CTNNB1oncoprotein340.235303.633Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
Atx10homo_assoc (PF09759, IPR019156): Spinocerebellar ataxia type 10 protein domain
DUF3361 (PF11841, IPR024574): Domain of unknown function (DUF3361)
HEAT_EZ (PF13513): HEAT-like repeat
48 CUL3protein found in more fusions660.2051193.954Cullin (PF00888, IPR001373, SM00182): Cullin family
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
WAC_Acf1_DNA_bd (PF10537, IPR013136): ATP-utilising chromatin assembly and remodelling N-terminal
49 CUL4Aprotein found in more fusions280.333168.534Cullin (PF00888, IPR001373, SM00182): Cullin family
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
50 CUL7protein found in more fusions450.215412.611ANAPC10 (PF03256, IPR004939): Anaphase-promoting complex, subunit 10 (APC10)
Cullin (PF00888, IPR001373, SM00182): Cullin family
DUF1918 (PF08940, IPR015035): Domain of unknown function (DUF1918)
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
Cul7 (PF11515, IPR021097): Mouse development and cellular proliferation protein Cullin-7
51 CXCR1interactor21.00007tm_1 (PF00001, IPR000276): 7 transmembrane receptor (rhodopsin family)
DUF2909 (PF11137, IPR021313): Protein of unknown function (DUF2909)
52 CYLDsuppressor100.40021.458CAP_GLY (PF01302, IPR000938, SM01052): CAP-Gly domain
UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase
zf-HIT (PF04438, IPR007529): HIT zinc finger
CYLD_phos_site (PF16607): Phosphorylation region of CYLD, unstructured
53 DAG1interactor80.42910.794DAG1 (PF05454, IPR008465): Dystroglycan (Dystrophin-associated glycoprotein 1)
54 DDX39Ainteractor110.28942.863DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
55 DFFAsuppressor80.500127.485CIDE-N (PF02017, IPR003508): CIDE-N domain
DFF-C (PF09033, IPR015121): DNA Fragmentation factor 45kDa, C terminal domain
T2SSppdC (PF12528, IPR022204): Type II secretion prepilin peptidase dependent protein C
SAPIS-gp6 (PF16722, IPR031999): Pathogenicity island protein gp6 in Staphylococcus
56 DNAJA4interactor70.3336.000DnaJ (PF00226, IPR001623, SM00271): DnaJ domain
DnaJ_C (PF01556, IPR002939): DnaJ C terminal domain
57 DNAJB11interactor140.42925.570DnaJ (PF00226, IPR001623, SM00271): DnaJ domain
DnaJ_C (PF01556, IPR002939): DnaJ C terminal domain
58 DNASE2Binteractor30.6670.105DNase_II (PF03265, IPR004947): Deoxyribonuclease II
59 DNMBPinteractor21.0000BAR (PF03114, IPR004148, SM00721): BAR domain
HR1 (PF02185, IPR011072, SM00742): Hr1 repeat
IncA (PF04156, IPR007285): IncA protein
RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain
SH3_2 (PF07653, IPR011511): Variant SH3 domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
SH3_9 (PF14604, IPR001452): Variant SH3 domain
60 DUSP23interactor30.3337.731DSPc (PF00782, IPR020422, SM00195): Dual specificity phosphatase, catalytic domain
Y_phosphatase2 (PF03162, IPR004861): Tyrosine phosphatase family
PTPlike_phytase (PF14566): Inositol hexakisphosphate
61 EEDsuppressor220.205157.900WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
62 EGFRoncoprotein630.2271054.741Furin-like (PF00757, IPR006211): Furin-like cysteine rich region
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
Recep_L_domain (PF01030, IPR000494): Receptor L domain
GAPT (PF11770, IPR021082): GRB2-binding adapter (GAPT)
GF_recep_IV (PF14843, IPR032778): Growth factor receptor domain IV
63 EML1interactor60.7002.961HELP (PF03451, IPR005108): HELP motif
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
PKcGMP_CC (PF16808, IPR031831): Coiled-coil N-terminus of cGMP-dependent protein kinase
64 ERBB3oncoprotein220.338102.521Furin-like (PF00757, IPR006211): Furin-like cysteine rich region
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
Recep_L_domain (PF01030, IPR000494): Receptor L domain
GF_recep_IV (PF14843, IPR032778): Growth factor receptor domain IV
65 ERLIN2interactor110.45535.846Band_7 (PF01145, IPR001107, SM00244): SPFH domain / Band 7 family
DUF4346 (PF14251, IPR025595): Domain of unknown function (DUF4346)
66 ERRFI1suppressor130.63617.838GTPase_binding (PF09027, IPR015116): GTPase binding
Inhibitor_Mig-6 (PF11555, IPR021619): EGFR receptor inhibitor Mig-6
67 ESR1suppressor510.213723.862Oest_recep (PF02159, IPR001292): Oestrogen receptor
zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains)
Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
ESR1_C (PF12743, IPR024736): Oestrogen-type nuclear receptor final C-terminal
68 ESRRBsuppressor140.61513.353zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains)
Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
69 EZH2suppressor230.121204.430CDC45 (PF02724, IPR003874): CDC45-like protein
TCR (PF03638, IPR005172, SM01114): Tesmin/TSO1-like CXC domain, cysteine-rich domain
SET (PF00856, IPR001214, SM00317): SET domain
EZH2_WD-Binding (PF11616, IPR021654): WD repeat binding protein EZH2
Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal
70 FAF2interactor190.39961.968DUF1682 (PF07946, IPR012879): Protein of unknown function (DUF1682)
UBX (PF00789, IPR001012, SM00166): UBX domain
Thioredoxin_7 (PF13899): Thioredoxin-like
UBA_4 (PF14555): UBA-like domain
71 FAM110Cinteractor21.0000FAM110_C (PF14160, IPR025741): Centrosome-associated C terminus
FAM110_N (PF14161, IPR025739): Centrosome-associated N terminus
LELP1 (PF15042, IPR026076): Late cornified envelope-like proline-rich protein 1
72 FAM187Binteractor100Ig_3 (PF13927): Immunoglobulin domain
73 FBXO6interactor410.217525.986FBA (PF04300, IPR007397): F-box associated region
F-box-like (PF12937, IPR001810): F-box-like
74 FBXW7suppressor220.167215.657Mem_trans (PF03547, IPR004776): Membrane transport protein
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160
F-box-like (PF12937, IPR001810): F-box-like
75 FCGR3Binteractor21.0000Ig_2 (PF13895, IPR007110): Immunoglobulin domain
76 FKBP5interactor160.40864.947FKBP_C (PF00254, IPR001179): FKBP-type peptidyl-prolyl cis-trans isomerase
TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
TPR_19 (PF14559): Tetratricopeptide repeat
NuDC (PF16273, IPR032572): Nuclear distribution C domain
77 FKBPLinteractor80.4295.095BTAD (PF03704, IPR005158, SM01043): Bacterial transcriptional activator domain
TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
TPR_11 (PF13414, IPR011990): TPR repeat
78 FN1oncoprotein420.226438.461fn1 (PF00039, IPR000083, SM00058): Fibronectin type I domain
fn2 (PF00040, IPR000562, SM00059): Fibronectin type II domain
fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369)
79 FUSsuppressor380.373374.457Herpes_PAP (PF03325, IPR004997): Herpesvirus polymerase accessory protein
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
SVS_QK (PF10578, IPR018942): Seminal vesicle protein repeat
zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others
Limkain-b1 (PF11608, IPR024582): Limkain b1
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
Keratin_2_head (PF16208, IPR032444): Keratin type II head
80 GANprotein found in more fusions160.45752.622BACK (PF07707, IPR011705, SM00875): BTB And C-terminal Kelch
BTB (PF00651, IPR013069, SM00225): BTB/POZ domain
Kelch_1 (PF01344, IPR006652, SM00612): Kelch motif
Kelch_3 (PF13415): Galactose oxidase, central domain
Kelch_5 (PF13854): Kelch motif
81 GAPDHoncoprotein460.274434.538Gp_dh_C (PF02800, IPR020829): Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain
Gp_dh_N (PF00044, IPR020828, SM00846): Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain
OstA (PF03968, IPR005653): OstA-like protein
82 GEMIN7interactor40.5006.665Gemin7 (PF11095, IPR020338): Gem-associated protein 7 (Gemin7)
SUZ-C (PF12901, IPR024642): SUZ-C motif
83 GSK3Bsuppressor180.28784.277Pkinase (PF00069, IPR000719): Protein kinase domain
84 GZMBinteractor21.0000Trypsin (PF00089, IPR001254, SM00020): Trypsin
85 GZMMinteractor205.052Trypsin (PF00089, IPR001254, SM00020): Trypsin
86 HAUS1interactor90.6433.694THP2 (PF09432, IPR018557): Tho complex subunit THP2
XhlA (PF10779, IPR019715): Haemolysin XhlA
DUF3496 (PF12001, IPR021885): Domain of unknown function (DUF3496)
87 HDAC3suppressor210.258141.827Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
88 HDAC5protein found in more fusions350.316194.400Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
NOA36 (PF06524, IPR010531): NOA36 protein
Activator_LAG-3 (PF11498, IPR021587): Transcriptional activator LAG-3
HDAC4_Gln (PF12203, IPR024643): Glutamine rich N terminal domain of histone deacetylase 4
89 HDAC6oncoprotein360.304292.281Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
PSGP (PF07276, IPR009900): Apopolysialoglycoprotein (PSGP)
zf-UBP (PF02148, IPR001607, SM00290): Zn-finger in ubiquitin-hydrolases and other protein
90 HSP90AA1oncoprotein870.1752221.247HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
HSP90 (PF00183, IPR001404): Hsp90 protein
91 HSP90AB1oncoprotein750.2181187.720HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
HSP90 (PF00183, IPR001404): Hsp90 protein
92 HSPA8oncoprotein870.1672175.223HSP70 (PF00012, IPR013126): Hsp70 protein
93 HTRA2suppressor80.5245.354Peptidase_S32 (PF05579, IPR008760): Equine arteritis virus serine endopeptidase S32
PDZ_2 (PF13180, IPR001478): PDZ domain
Trypsin_2 (PF13365): Trypsin-like peptidase domain
94 HTTprotein found in more fusions140.46255.374HEAT (PF02985, IPR000357): HEAT repeat
SPX (PF03105, IPR004331): SPX domain
TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
DUF3652 (PF12372, IPR024613): Huntingtin protein region
Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region
HEAT_EZ (PF13513): HEAT-like repeat
HEAT_2 (PF13646): HEAT repeats
95 ID2oncoprotein60.6002.031HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
96 IFNEinteractor100Interferon (PF00143, IPR000471, SM00076): Interferon alpha/beta domain
97 IGSF8oncoprotein110.50939.323V-set (PF07686, IPR013106): Immunoglobulin V-set domain
Ig_2 (PF13895, IPR007110): Immunoglobulin domain
Ig_3 (PF13927): Immunoglobulin domain
98 IL12RB1interactor40.6673.364fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
Pur_ac_phosph_N (PF16656, IPR015914): Purple acid Phosphatase, N-terminal domain
99 INO80interactor40.5001.984Peptidase_S49_N (PF08496, IPR013703): Peptidase family S49 N-terminal
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
RNA_pol_Rbc25 (PF08292, IPR013238): RNA polymerase III subunit Rpc25
SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain
POTRA (PF07244, IPR010827): Surface antigen variable number repeat
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
DBINO (PF13892, IPR020838): DNA-binding domain
FAM176 (PF14851): FAM176 family
MAP17 (PF15807, IPR031627): Membrane-associated protein 117 kDa, PDZK1-interacting protein 1
100 INPPL1oncoprotein190.52033.715Exo_endo_phos (PF03372, IPR005135): Endonuclease/Exonuclease/phosphatase family
SAM_1 (PF00536, IPR021129, SM00454): SAM domain (Sterile alpha motif)
SH2 (PF00017, IPR000980, SM00252): SH2 domain
101 IQCB1interactor210.376128.689DUF1765 (PF08578, IPR013887): Protein of unknown function (DUF1765)
IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif
HJURP_C (PF12347, IPR022102): Holliday junction regulator protein family C-terminal repeat
Condensin2nSMC (PF12422, IPR024741): Condensin II non structural maintenance of chromosomes subunit
102 IRS4interactor290.249228.739CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator
IRS (PF02174, IPR002404, SM00310): PTB domain (IRS-1 type)
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
TAT_signal (PF10518, IPR019546): TAT (twin-arginine translocation) pathway signal sequence
PH_11 (PF15413): Pleckstrin homology domain
103 ISLRinteractor40.5009.991I-set (PF07679, IPR013098): Immunoglobulin I-set domain
LRRCT (PF01463, IPR000483, SM00082): Leucine rich repeat C-terminal domain
LRR_8 (PF13855, IPR001611): Leucine rich repeat
TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain
104 ITGB1suppressor130.30847.928EGF_2 (PF07974, IPR013111): EGF-like domain
Integrin_b_cyt (PF08725, IPR014836): Integrin beta cytoplasmic domain
Integrin_B_tail (PF07965, IPR012896): Integrin beta tail domain
Integrin_beta (PF00362, IPR002369, SM00187): Integrin beta chain VWA domain
PSI_integrin (PF17205): Integrin plexin domain
105 KCND3interactor40.3331.035Ion_trans (PF00520, IPR005821): Ion transport protein
BTB_2 (PF02214, IPR003131): BTB/POZ domain
Shal-type (PF11601, IPR021645): Shal-type voltage-gated potassium channels, N-terminal
DUF3399 (PF11879, IPR024587): Domain of unknown function (DUF3399)
106 KELinteractor31.0000Peptidase_M13 (PF01431, IPR018497): Peptidase family M13
Peptidase_M13_N (PF05649, IPR008753): Peptidase family M13
107 KIAA0368interactor130.385160.460HEAT (PF02985, IPR000357): HEAT repeat
IFRD (PF05004, IPR007701): Interferon-related developmental regulator (IFRD)
CLASP_N (PF12348, IPR024395): CLASP N terminal
MMS19_C (PF12460, IPR024687): RNAPII transcription regulator C-terminal
Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region
Sec7_N (PF12783, IPR032691): Guanine nucleotide exchange factor in Golgi transport N-terminal
Ecm29 (PF13001, IPR024372): Proteasome stabiliser
HEAT_EZ (PF13513): HEAT-like repeat
HEAT_2 (PF13646): HEAT repeats
108 KIF5Binteractor150.27671.542ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16)
Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein
Sec2p (PF06428, IPR009449): GDP/GTP exchange factor Sec2p
Kinesin (PF00225, IPR001752, SM00129): Kinesin motor domain
DUF3584 (PF12128, IPR021979): Protein of unknown function (DUF3584)
HAUS-augmin3 (PF14932, IPR032733): HAUS augmin-like complex subunit 3
DUF4226 (PF10774, IPR019710): Domain of unknown function (DUF4226)
PRKG1_interact (PF15898, IPR031775): cGMP-dependent protein kinase interacting domain
109 KLK11oncoprotein40.6673.364Trypsin (PF00089, IPR001254, SM00020): Trypsin
110 KLK5oncoprotein50.5006.470Trypsin (PF00089, IPR001254, SM00020): Trypsin
111 KPNB1protein found in more fusions350.257331.496Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
HEAT (PF02985, IPR000357): HEAT repeat
IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain
V-ATPase_H_C (PF11698, IPR011987): V-ATPase subunit H
CLASP_N (PF12348, IPR024395): CLASP N terminal
Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1
HEAT_EZ (PF13513): HEAT-like repeat
112 LAMP2protein found in more fusions70.6004.128Lamp (PF01299, IPR002000): Lysosome-associated membrane glycoprotein (Lamp)
113 LGALS2interactor30.66717.231Gal-bind_lectin (PF00337, IPR001079, SM00908): Galactoside-binding lectin
114 LGALS3BPoncoprotein300.43695.094BACK (PF07707, IPR011705, SM00875): BTB And C-terminal Kelch
SRCR (PF00530, IPR001190): Scavenger receptor cysteine-rich domain
SRCR_2 (PF15494, IPR017448): Scavenger receptor cysteine-rich domain
115 LGR4interactor90.3218.5317tm_1 (PF00001, IPR000276): 7 transmembrane receptor (rhodopsin family)
LRR_1 (PF00560, IPR001611): Leucine Rich Repeat
LRRNT (PF01462, IPR000372, SM00013): Leucine rich repeat N-terminal domain
LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies)
LRR_8 (PF13855, IPR001611): Leucine rich repeat
116 LIPHinteractor21.0000Lipase (PF00151, IPR013818): Lipase
117 LRRK2oncoprotein150.51649.955Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
ATP-synt_ab (PF00006, IPR000194): ATP synthase alpha/beta family, nucleotide-binding domain
DUF1043 (PF06295, IPR009386): Protein of unknown function (DUF1043)
T2SSE (PF00437, IPR001482): Type II/IV secretion system protein
Roc (PF08477, IPR013684): Ras of Complex, Roc, domain of DAPkinase
Pkinase (PF00069, IPR000719): Protein kinase domain
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies)
PQQ_2 (PF13360, IPR002372): PQQ-like domain
LRR_8 (PF13855, IPR001611): Leucine rich repeat
COR (PF16095, IPR032171): C-terminal of Roc, COR, domain
118 LTAoncoprotein21.0000TNF (PF00229, IPR006052, SM00207): TNF(Tumour Necrosis Factor) family
119 LTV1interactor60.2677.165DUF1874 (PF08960, IPR015055): Domain of unknown function (DUF1874)
LTV (PF04180, IPR007307): Low temperature viability protein
120 MAGED2interactor230.50272.395CDC27 (PF09507, IPR019038): DNA polymerase subunit Cdc27
MAGE (PF01454, IPR002190): MAGE family
SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal
DUF3306 (PF11748, IPR021735): Protein of unknown function (DUF3306)
121 MAP1LC3Ainteractor100.44415.622Atg8 (PF02991, IPR004241): Autophagy protein Atg8 ubiquitin like
122 MAP2oncoprotein60.6004.657MAP2_projctn (PF08377, IPR013588): MAP2/Tau projection domain
Tubulin-binding (PF00418, IPR001084): Tau and MAP protein, tubulin-binding repeat
RII_binding_1 (PF10522, IPR018459): RII binding domain
CCSAP (PF15748, IPR029774): Centriole, cilia and spindle-associated
123 MAP7D3interactor50.7001.336DUF572 (PF04502, IPR007590): Family of unknown function (DUF572)
MAP7 (PF05672, IPR008604): MAP7 (E-MAP-115) family
Sec62 (PF03839, IPR004728): Translocation protein Sec62
Nop25 (PF09805, IPR019186): Nucleolar protein 12 (25kDa)
ARGLU (PF15346): Arginine and glutamate-rich 1
124 MAPK6oncoprotein100.25049.122Pkinase (PF00069, IPR000719): Protein kinase domain
125 MAPRE1oncoprotein200.275105.506CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
EB1 (PF03271, IPR004953): EB1-like C-terminal motif
SUIM_assoc (PF16619): Unstructured region C-term to UIM in Ataxin3
126 MAPTprotein found in more fusions210.326123.425Tubulin-binding (PF00418, IPR001084): Tau and MAP protein, tubulin-binding repeat
127 MARK4oncoprotein80.28656.886KA1 (PF02149, IPR001772): Kinase associated domain 1
Pkinase (PF00069, IPR000719): Protein kinase domain
UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
128 MAT2Asuppressor130.48514.326S-AdoMet_synt_C (PF02773, IPR022630): S-adenosylmethionine synthetase, C-terminal domain
S-AdoMet_synt_M (PF02772, IPR022629): S-adenosylmethionine synthetase, central domain
S-AdoMet_synt_N (PF00438, IPR022628): S-adenosylmethionine synthetase, N-terminal domain
129 MAT2Binteractor80.7143.334RmlD_sub_bind (PF04321, IPR005913): RmlD substrate binding domain
130 MAXsuppressor100.38923.433ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16)
HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
SlyX (PF04102, IPR007236): SlyX
131 MCM2oncoprotein510.288425.992AAA_3 (PF07726, IPR011703): ATPase family associated with various cellular activities (AAA)
MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family
MCM2_N (PF12619, IPR008045): Mini-chromosome maintenance protein 2
MCM_N (PF14551, IPR027925): MCM N-terminal domain
MCM_OB (PF17207): MCM OB domain
132 MDKoncoprotein40.16713.854PTN_MK_C (PF01091, IPR020090): PTN/MK heparin-binding protein family, C-terminal domain
PTN_MK_N (PF05196, IPR020089): PTN/MK heparin-binding protein family, N-terminal domain
133 MED23interactor70.23829.904Med23 (PF11573, IPR021629): Mediator complex subunit 23
134 MID1oncoprotein110.28935.647Baculo_PEP_C (PF04513, IPR007601): Baculovirus polyhedron envelope protein, PEP, C terminus
fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
SPRY (PF00622, IPR003877, SM00449): SPRY domain
DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369)
zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger
PRY (PF13765, IPR006574, SM00589): SPRY-associated domain
zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger
zf-C3HC4_4 (PF15227): zinc finger of C3HC4-type, RING
135 MID2interactor70.53312.264fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
SPRY (PF00622, IPR003877, SM00449): SPRY domain
zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger
PRY (PF13765, IPR006574, SM00589): SPRY-associated domain
zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger
CEBP_ZZ (PF16366, IPR032296): Cytoplasmic polyadenylation element-binding protein ZZ domain
APC_u15 (PF16636): Unstructured region on APC between APC_crr regions 5 and 6
136 MLST8interactor60.26724.091Hira (PF07569, IPR011494): TUP1-like enhancer of split
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160
137 MORF4L1interactor80.7144.057MRG (PF05712, IPR026541): MRG
Fmp27_WPPW (PF10359, IPR019449): RNA pol II promoter Fmp27 protein domain
Tudor-knot (PF11717, IPR025995): RNA binding activity-knot of a chromodomain
138 MORF4L2interactor70.61913.153MRG (PF05712, IPR026541): MRG
139 MRGBPinteractor70.6674.692Eaf7 (PF07904, IPR012423): Chromatin modification-related protein EAF7
140 MTCL1interactor70.26715.760bZIP_1 (PF00170, IPR004827): bZIP transcription factor
Cnn_1N (PF07989, IPR012943): Centrosomin N-terminal motif 1
TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein
SOGA (PF11365, IPR027881): Protein SOGA
DUF4140 (PF13600, IPR025554): N-terminal domain of unknown function (DUF4140)
DUF4201 (PF13870, IPR025254): Domain of unknown function (DUF4201)
DUF4407 (PF14362, IPR025519): Domain of unknown function (DUF4407)
DUF4482 (PF14818, IPR027882): Domain of unknown function (DUF4482)
HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1
141 MX1interactor200Dynamin_M (PF01031, IPR000375): Dynamin central region
GED (PF02212, IPR003130, SM00302): Dynamin GTPase effector domain
Dynamin_N (PF00350, IPR001401, SM00053): Dynamin family
142 MYConcoprotein440.229492.901HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
Myc-LZ (PF02344, IPR003327): Myc leucine zipper domain
Myc_N (PF01056, IPR012682): Myc amino-terminal region
143 MYO19interactor70.19019.623IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif
Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain)
144 NAAAinteractor21.0000CBAH (PF02275, IPR003199): Linear amide C-N hydrolases, choloylglycine hydrolase family
NAAA-beta (PF15508, IPR029130): beta subunit of N-acylethanolamine-hydrolyzing acid amidase
145 NANOGinteractor150.29751.104Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
146 NCK1oncoprotein90.50024.427SH2 (PF00017, IPR000980, SM00252): SH2 domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
SH3_9 (PF14604, IPR001452): Variant SH3 domain
147 NCOA6oncoprotein100.41741.071DUF719 (PF05334, IPR007998): Protein of unknown function (DUF719)
Fes1 (PF08609, IPR013918): Nucleotide exchange factor Fes1
Presenilin (PF01080, IPR001108): Presenilin
DUF3729 (PF12526, IPR022202): Protein of unknown function (DUF3729)
Nucleic_acid_bd (PF13820, IPR032715): Putative nucleic acid-binding region
NST1 (PF13945, IPR025279): Salt tolerance down-regulator
148 NDEL1protein found in more fusions60.4003.106HALZ (PF02183, IPR003106, SM00340): Homeobox associated leucine zipper
NUDE_C (PF04880, IPR006964): NUDE protein, C-terminal conserved region
TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein
PRKG1_interact (PF15898, IPR031775): cGMP-dependent protein kinase interacting domain
149 NEK8interactor50.5006.324Pkinase (PF00069, IPR000719): Protein kinase domain
RCC1 (PF00415, IPR000408): Regulator of chromosome condensation (RCC1) repeat
RCC1_2 (PF13540): Regulator of chromosome condensation (RCC1) repeat
150 NFATC1oncoprotein60.7331.128RHD_DNA_bind (PF00554, IPR011539): Rel homology DNA-binding domain
RHD_dimer (PF16179, IPR032397): Rel homology dimerisation domain
151 NFATC2suppressor40.6670.709RHD_DNA_bind (PF00554, IPR011539): Rel homology DNA-binding domain
RHD_dimer (PF16179, IPR032397): Rel homology dimerisation domain
152 NOP56interactor170.33886.680Cytochrom_NNT (PF03264, IPR005126): NapC/NirT cytochrome c family, N-terminal region
Nop (PF01798, IPR002687): snoRNA binding domain, fibrillarin
NOP5NT (PF08156, IPR012974): NOP5NT (NUC127) domain
RNA_polI_A34 (PF08208, IPR013240): DNA-directed RNA polymerase I subunit RPA34.5
SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal
153 NTRK1oncoprotein820.1751973.482I-set (PF07679, IPR013098): Immunoglobulin I-set domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
LRR_8 (PF13855, IPR001611): Leucine rich repeat
TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain
154 NUDT3interactor30.6670.286NUDIX (PF00293, IPR000086): NUDIX domain
155 NXPH3interactor30.6672.302Neurexophilin (PF06312, IPR026845): Neurexophilin
156 OBSL1interactor340.314153.474BiPBP_C (PF06832, IPR009647): Penicillin-Binding Protein C-terminus Family
fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
Herpes_gE (PF02480, IPR003404): Alphaherpesvirus glycoprotein E
I-set (PF07679, IPR013098): Immunoglobulin I-set domain
V-set (PF07686, IPR013106): Immunoglobulin V-set domain
Ig_3 (PF13927): Immunoglobulin domain
Ig_4 (PF16680, IPR032052): T-cell surface glycoprotein CD3 delta chain
Izumo-Ig (PF16706, IPR032699): Izumo-like Immunoglobulin domain
157 OFD1protein found in more fusions130.37943.662APG6 (PF04111, IPR007243): Autophagy protein Apg6
Exonuc_VII_L (PF02601, IPR020579): Exonuclease VII, large subunit
GrpE (PF01025, IPR000740): GrpE
NPV_P10 (PF05531, IPR008702): Nucleopolyhedrovirus P10 protein
XhlA (PF10779, IPR019715): Haemolysin XhlA
DUF3372 (PF11852, IPR024561): Domain of unknown function (DUF3372)
LisH_2 (PF16045, IPR006594): LisH
158 OTUD4interactor50.5002.713OTU (PF02338, IPR003323): OTU-like cysteine protease
Presenilin (PF01080, IPR001108): Presenilin
Peptidase_C65 (PF10275, IPR019400): Peptidase C65 Otubain
159 PACRGsuppressor70.7144.510ParcG (PF10274, IPR019399): Parkin co-regulated protein
160 PAFAH1B1suppressor80.5249.381LisH (PF08513, IPR013720, SM00667): LisH
Pox_A_type_inc (PF04508, IPR007596): Viral A-type inclusion protein repeat
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
161 PAN2interactor210.329104.263RNase_T (PF00929, IPR013520): Exonuclease
UCH_1 (PF13423, IPR001394): Ubiquitin carboxyl-terminal hydrolase
WD40_like (PF17005, IPR031544): WD40-like domain
162 PARK2suppressor470.235640.707IBR (PF01485, IPR002867, SM00647): IBR domain, a half RING-finger domain
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
163 PDCD6IPinteractor140.32180.115BRO1 (PF03097, IPR004328, SM01041): BRO1-like domain
MSA-2c (PF12238, IPR021060): Merozoite surface antigen 2c
ALIX_LYPXL_bnd (PF13949, IPR025304): ALIX V-shaped domain binding to HIV
164 PEX14protein found in more fusions140.38531.333HemX (PF04375, IPR007470): HemX, putative uroporphyrinogen-III C-methyltransferase
Pex14_N (PF04695, IPR006785): Peroxisomal membrane anchor protein (Pex14p) conserved region
CPSF100_C (PF13299, IPR025069): Cleavage and polyadenylation factor 2 C-terminal
PTPRCAP (PF15713, IPR016553): Protein tyrosine phosphatase receptor type C-associated
TolA_bind_tri (PF16331, IPR032519): TolA binding protein trimerisation
165 PFDN1interactor40.16724.206Prefoldin_2 (PF01920, IPR002777): Prefoldin subunit
166 PIK3R1oncoprotein220.286137.206RhoGAP (PF00620, IPR000198, SM00324): RhoGAP domain
SH2 (PF00017, IPR000980, SM00252): SH2 domain
SH3_2 (PF07653, IPR011511): Variant SH3 domain
PI3K_P85_iSH2 (PF16454, IPR032498): Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain
167 PINK1protein found in more fusions150.44042.690Pkinase (PF00069, IPR000719): Protein kinase domain
168 PIWIL1interactor40.5002.017ArgoL1 (PF08699, IPR014811, SM01163): Argonaute linker 1 domain
GAGE (PF05831, IPR008625): GAGE protein
PAZ (PF02170, IPR003100, SM00949): PAZ domain
Piwi (PF02171, IPR003165, SM00950): Piwi domain
ArgoN (PF16486, IPR032474): N-terminal domain of argonaute
169 PKN1interactor160.295100.539C2 (PF00168, IPR000008, SM00239): C2 domain
HR1 (PF02185, IPR011072, SM00742): Hr1 repeat
Pkinase (PF00069, IPR000719): Protein kinase domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
170 PLAURoncoprotein30.6670.590Toxin_1 (PF00087, IPR003571): Snake toxin
UPAR_LY6 (PF00021, IPR001526): u-PAR/Ly-6 domain
171 PLK1suppressor230.241206.716Pkinase (PF00069, IPR000719): Protein kinase domain
POLO_box (PF00659, IPR000959): POLO box duplicated region
172 POLHoncoprotein60.4673.554IMS (PF00817, IPR001126): impB/mucB/samB family
IMS_HHH (PF11798, IPR024728): IMS family HHH motif
IMS_C (PF11799, IPR017961): impB/mucB/samB family C-terminal domain
PRP21_like_P (PF12230, IPR022030): Pre-mRNA splicing factor PRP21 like protein
173 POU5F1oncoprotein270.246166.748Pou (PF00157, IPR000327, SM00352): Pou domain - N-terminal to homeobox domain
Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
174 PPIDinteractor100.6679.359Pro_isomerase (PF00160, IPR002130): Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD
TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
ANAPC3 (PF12895): Anaphase-promoting complex, cyclosome, subunit 3
TPR_7 (PF13176, IPR019734): Tetratricopeptide repeat
175 PRG2interactor50.30023.780Lectin_C (PF00059, IPR001304, SM00034): Lectin C-type domain
DUF4628 (PF15429, IPR027851): Domain of unknown function (DUF4628)
176 PRKAA1suppressor150.39092.214Pkinase (PF00069, IPR000719): Protein kinase domain
AdenylateSensor (PF16579, IPR032270): Adenylate sensor of SNF1-like protein kinase
177 PRKCSHinteractor70.3335.327CDC45 (PF02724, IPR003874): CDC45-like protein
Ax_dynein_light (PF10211, IPR019347): Axonemal dynein light chain
PRKCSH-like (PF12999, IPR028146): Glucosidase II beta subunit-like
PRKCSH_1 (PF13015, IPR009011): Glucosidase II beta subunit-like protein
EF-hand_5 (PF13202, IPR002048): EF hand
178 PSEN1oncoprotein110.20024.247Presenilin (PF01080, IPR001108): Presenilin
LRRC37AB_C (PF14914, IPR029423): LRRC37A/B like protein 1 C-terminal domain
179 PSMA3protein found in more fusions290.304176.518Proteasome (PF00227, IPR001353): Proteasome subunit
Proteasome_A_N (PF10584, IPR000426, SM00948): Proteasome subunit A N-terminal signature
180 PSMC4interactor160.38328.598AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA)
NTPase_1 (PF03266, IPR004948): NTPase
CENP-F_leu_zip (PF10473, IPR019513): Leucine-rich repeats of kinetochore protein Cenp-F/LEK1
AAA_16 (PF13191): AAA ATPase domain
181 PSMD1interactor190.48541.391PA26 (PF04636, IPR006730): PA26 p53-induced protein (sestrin)
PC_rep (PF01851, IPR002015): Proteasome/cyclosome repeat
HEAT_2 (PF13646): HEAT repeats
182 PTENsuppressor200.38969.310DSPc (PF00782, IPR020422, SM00195): Dual specificity phosphatase, catalytic domain
PTEN_C2 (PF10409, IPR014020): C2 domain of PTEN tumour-suppressor protein
183 PTPAsuppressor110.16456.100PTPA (PF03095, IPR004327): Phosphotyrosyl phosphate activator (PTPA) protein
184 RAB8Boncoprotein60.4674.305Ras (PF00071, IPR001806, SM00173): Ras family
185 RAD52oncoprotein70.7331.405Rad52_Rad22 (PF04098, IPR007232): Rad52/22 family double-strand break repair protein
DUF2335 (PF10097, IPR019284): Predicted membrane protein (DUF2335)
186 RANBP9suppressor150.22079.555Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator
LisH (PF08513, IPR013720, SM00667): LisH
SPRY (PF00622, IPR003877, SM00449): SPRY domain
CLTH (PF10607, IPR024964): CTLH/CRA C-terminal to LisH motif domain
187 RBBP5oncoprotein140.23153.618WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
DUF2457 (PF10446, IPR018853): Protein of unknown function (DUF2457)
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
188 RBX1oncoprotein150.26437.970zf-rbx1 (PF12678, IPR024766): RING-H2 zinc finger domain
189 RCN1interactor140.20955.425EF-hand_1 (PF00036, IPR002048, SM00054): EF hand
EF-hand_4 (PF12763, IPR000261): Cytoskeletal-regulatory complex EF hand
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
190 RICTORinteractor120.27376.341RasGEF_N_2 (PF14663, IPR029453): Rapamycin-insensitive companion of mTOR RasGEF_N domain
RICTOR_N (PF14664, IPR028267): Rapamycin-insensitive companion of mTOR, N-term
RICTOR_phospho (PF14665, IPR029259): Rapamycin-insensitive companion of mTOR, phosphorylation-site
RICTOR_M (PF14666, IPR029451): Rapamycin-insensitive companion of mTOR, middle domain
RICTOR_V (PF14668, IPR029452): Rapamycin-insensitive companion of mTOR, domain 5
191 RNF2interactor290.190183.865zf-C4_Topoisom (PF01396, IPR013498): Topoisomerase DNA binding C4 zinc finger
zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
RAWUL (PF16207, IPR032443): RAWUL domain RING finger- and WD40-associated ubiquitin-like
192 RPGRoncoprotein60.6674.241PSK (PF06404, IPR009438): Phytosulfokine precursor protein (PSK)
RCC1 (PF00415, IPR000408): Regulator of chromosome condensation (RCC1) repeat
Kelch_4 (PF13418): Galactose oxidase, central domain
RCC1_2 (PF13540): Regulator of chromosome condensation (RCC1) repeat
193 RPL18interactor270.27186.589Ribosomal_L18 (PF17135): Ribosomal protein 60S L18 and 50S L18e
194 RPL5suppressor290.347120.851Ribosomal_L18_c (PF14204, IPR025607): Ribosomal L18 C-terminal region
Ribosomal_L5e (PF17144): Ribosomal large subunit proteins 60S L5, and 50S L18
195 RPLP0P6interactor80.50021.618NA
196 RPS6KB2interactor200.31674.619Pkinase (PF00069, IPR000719): Protein kinase domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
197 RUFY1interactor50.8331.288DM (PF00751, IPR001275, SM00301): DM DNA binding domain
FAA_hydrolase_N (PF09298, IPR015377): Fumarylacetoacetase N-terminal
DUF641 (PF04859, IPR006943): Plant protein of unknown function (DUF641)
DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972)
FYVE (PF01363, IPR000306, SM00064): FYVE zinc finger
RUN (PF02759, IPR004012, SM00593): RUN domain
Tektin (PF03148, IPR000435): Tektin family
198 RUVBL1oncoprotein420.207588.965TIP49 (PF06068, IPR010339): TIP49 C-terminus
199 SCPEP1interactor40.8330.754Peptidase_S10 (PF00450, IPR001563): Serine carboxypeptidase
200 SDC3oncoprotein40.8330.189Glycophorin_A (PF01102, IPR001195): Glycophorin A
Syndecan (PF01034, IPR027789): Syndecan domain
201 SERPINB11interactor100Serpin (PF00079, IPR023796, SM00093): Serpin (serine protease inhibitor)
202 SF3B1oncoprotein280.325113.177Dopey_N (PF04118, IPR007249): Dopey, N-terminal
HEAT (PF02985, IPR000357): HEAT repeat
SF3b1 (PF08920, IPR015016): Splicing factor 3B subunit 1
UNC45-central (PF11701, IPR024660): Myosin-binding striated muscle assembly central
Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region
HEAT_EZ (PF13513): HEAT-like repeat
HEAT_2 (PF13646): HEAT repeats
203 SHC1oncoprotein340.367317.523PID (PF00640, IPR006020, SM00462): Phosphotyrosine interaction domain (PTB/PID)
SH2 (PF00017, IPR000980, SM00252): SH2 domain
204 SIRT6suppressor80.3219.604SIR2 (PF02146, IPR003000): Sir2 family
TPP_enzyme_M (PF00205, IPR012000): Thiamine pyrophosphate enzyme, central domain
205 SKIoncoprotein180.39762.005c-SKI_SMAD_bind (PF08782, IPR014890, SM01046): c-SKI Smad4 binding domain
Ski_Sno (PF02437, IPR003380): SKI/SNO/DAC family
SlyX (PF04102, IPR007236): SlyX
HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1
206 SLC6A3oncoprotein40.8330.655SNF (PF00209, IPR000175): Sodium:neurotransmitter symporter family
207 SLX1Binteractor40.3333.927GIY-YIG (PF01541, IPR000305, SM00465): GIY-YIG catalytic domain
FANCL_C (PF11793, IPR026850): FANCL C-terminal domain
208 SMAD2suppressor140.43628.208MH1 (PF03165, IPR003619, SM00523): MH1 domain
MH2 (PF03166, IPR001132, SM00524): MH2 domain
209 SMG1interactor60.6001.714Baculo_PEP_C (PF04513, IPR007601): Baculovirus polyhedron envelope protein, PEP, C terminus
DUF948 (PF06103, IPR009293): Bacterial protein of unknown function (DUF948)
FATC (PF02260, IPR003152): FATC domain
HEAT (PF02985, IPR000357): HEAT repeat
FRB_dom (PF08771, IPR009076): FKBP12-rapamycin binding domain
Xpo1 (PF08389, IPR013598): Exportin 1-like protein
KxDL (PF10241, IPR019371): Uncharacterized conserved protein
XhlA (PF10779, IPR019715): Haemolysin XhlA
PI3_PI4_kinase (PF00454, IPR000403, SM00146): Phosphatidylinositol 3- and 4-kinase
SMG1 (PF15785, IPR031559): Serine/threonine-protein kinase smg-1
210 SMN1interactor210.242197.674SMN (PF06003, IPR010304): Survival motor neuron protein (SMN)
211 SMURF1interactor220.267120.977C2 (PF00168, IPR000008, SM00239): C2 domain
WW (PF00397, IPR001202, SM00456): WW domain
HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
212 SNCAinteractor240.316162.492Synuclein (PF01387, IPR001058): Synuclein
213 SNRNP200protein found in more fusions280.313131.258DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
DUF603 (PF04645, IPR006739): Protein of unknown function, DUF603
Sec63 (PF02889, IPR004179, SM00973): Sec63 Brl domain
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
214 SNW1protein found in more fusions440.302343.868SKIP_SNW (PF02731, IPR004015): SKIP/SNW domain
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
SIR4_SID (PF16991, IPR031556): Sir4 SID domain
215 SOCS6interactor70.7626.315SH2 (PF00017, IPR000980, SM00252): SH2 domain
SOCS_box (PF07525, IPR001496): SOCS box
216 SOX2oncoprotein190.261137.439HMG_box (PF00505, IPR009071, SM00398): HMG (high mobility group) box
SOXp (PF12336, IPR022097): SOX transcription factor
217 SP1protein found in more fusions160.26758.604zf-Di19 (PF05605, IPR008598): Drought induced 19 protein (Di19), zinc-binding
Herpes_capsid (PF06112, IPR009299): Gammaherpesvirus capsid protein
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
Miga (PF10265, IPR019392): Mitoguardin
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
218 SPG20interactor50.7001.692MIT (PF04212, IPR007330, SM00745): MIT (microtubule interacting and transport) domain
Senescence (PF06911, IPR009686): Senescence-associated protein
219 SQSTM1oncoprotein250.239142.840PB1 (PF00564, IPR000270, SM00666): PB1 domain
ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type
UBA_5 (PF16577, IPR015940): UBA domain
220 SRPK2oncoprotein180.125145.101DUF1387 (PF07139, IPR009816): Protein of unknown function (DUF1387)
Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator
Pkinase (PF00069, IPR000719): Protein kinase domain
S-antigen (PF05756, IPR008825): S-antigen protein
DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360)
221 SSBP1interactor180.42630.149SSB (PF00436, IPR000424): Single-strand binding protein family
222 SSX2IPprotein found in more fusions160.23871.780ZapB (PF06005, IPR009252): Cell division protein ZapB
ERM (PF00769, IPR011259): Ezrin/radixin/moesin family
Surfac_D-trimer (PF09006, IPR015097): Lung surfactant protein D coiled-coil trimerisation
ADIP (PF11559, IPR021622): Afadin- and alpha -actinin-Binding
YqzH (PF14164, IPR025546): YqzH-like protein
223 STARD13suppressor21.0000RhoGAP (PF00620, IPR000198, SM00324): RhoGAP domain
SAM_2 (PF07647, IPR011510): SAM domain (Sterile alpha motif)
START (PF01852, IPR002913, SM00234): START domain
224 STAU1protein found in more fusions290.39495.437dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif
Staufen_C (PF16482, IPR032478): Staufen C-terminal domain
225 STK11suppressor100.40018.115Pkinase (PF00069, IPR000719): Protein kinase domain
226 STMN1interactor70.42911.173Stathmin (PF00836, IPR000956): Stathmin family
227 SUMO2interactor110.44429.491Rad60-SLD (PF11976, IPR022617): Ubiquitin-2 like Rad60 SUMO-like
228 SYKsuppressor170.35070.128Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
SH2 (PF00017, IPR000980, SM00252): SH2 domain
229 TAOK2interactor31.0000Band_3_cyto (PF07565, IPR013769): Band 3 cytoplasmic domain
DUF342 (PF03961, IPR005646): Protein of unknown function (DUF342)
Na_trans_assoc (PF06512, IPR010526): Sodium ion transport-associated
Pkinase (PF00069, IPR000719): Protein kinase domain
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
230 TARDBPinteractor280.41073.112RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
231 TBC1D3interactor30.3332.193RabGAP-TBC (PF00566, IPR000195, SM00164): Rab-GTPase-TBC domain
232 TERToncoprotein80.10735.105RVT_1 (PF00078, IPR000477): Reverse transcriptase (RNA-dependent DNA polymerase)
Telomerase_RBD (PF12009, IPR021891, SM00975): Telomerase ribonucleoprotein complex - RNA binding domain
233 THBS3oncoprotein41.0000EGF (PF00008, IPR000742, SM00181): EGF-like domain
EGF_CA (PF07645, IPR001881, SM00179): Calcium-binding EGF domain
Laminin_G_2 (PF02210, IPR001791): Laminin G domain
TSP_3 (PF02412, IPR003367): Thrombospondin type 3 repeat
TSP_C (PF05735, IPR008859): Thrombospondin C-terminal region
COMP (PF11598, IPR024665): Cartilage oligomeric matrix protein
cEGF (PF12662, IPR026823): Complement Clr-like EGF-like
EGF_3 (PF12947, IPR024731): EGF domain
234 THTPAinteractor100CYTH (PF01928, IPR023577, SM01118): CYTH domain
235 TIMM17Ainteractor100Tim17 (PF02466, IPR003397): Tim17/Tim22/Tim23/Pmp24 family
236 TK1oncoprotein150.25360.028TK (PF00265, IPR001267, SM00203): Thymidine kinase
237 TLN1interactor150.38142.635DUF1013 (PF06242, IPR010421): Protein of unknown function (DUF1013)
DUF948 (PF06103, IPR009293): Bacterial protein of unknown function (DUF948)
FERM_M (PF00373, IPR019748): FERM central domain
FERM_N (PF09379, IPR018979): FERM N-terminal domain
IRS (PF02174, IPR002404, SM00310): PTB domain (IRS-1 type)
Talin_middle (PF09141, IPR015224): Talin, middle domain
VBS (PF08913, IPR015009): Vinculin Binding Site
CoatB (PF10389, IPR008020): Bacteriophage coat protein B
LOH1CR12 (PF10158, IPR018780): Tumour suppressor protein
I_LWEQ (PF01608, IPR002558, SM00307): I/LWEQ domain
TAN (PF11640, IPR021668): Telomere-length maintenance and DNA damage repair
FERM_f0 (PF16511, IPR032425): N-terminal or F0 domain of Talin-head FERM
238 TMEM25interactor40.6674.932C2-set_2 (PF08205, IPR013162): CD80-like C2-set immunoglobulin domain
Ig_3 (PF13927): Immunoglobulin domain
DUF4674 (PF15719, IPR029779): Domain of unknown function (DUF4674)
239 TMEM253interactor100CD20 (PF04103, IPR007237): CD20-like family
240 TOM1L1interactor50.3004.658GAT (PF03127, IPR004152): GAT domain
VHS (PF00790, IPR002014, SM00288): VHS domain
241 TP53suppressor620.2011237.844DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region
P53 (PF00870, IPR011615): P53 DNA-binding domain
P53_tetramer (PF07710, IPR010991): P53 tetramerisation motif
242 TRACinteractor30.6671.207DUF11 (PF01345, IPR001434): Domain of unknown function DUF11
fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region
I-set (PF07679, IPR013098): Immunoglobulin I-set domain
Pkinase (PF00069, IPR000719): Protein kinase domain
PPAK (PF02818, IPR004168): PPAK motif
Titin_Z (PF09042, IPR015129): Titin Z
V-set (PF07686, IPR013106): Immunoglobulin V-set domain
Y_Y_Y (PF07495, IPR011123): Y_Y_Y domain
DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369)
Ig_3 (PF13927): Immunoglobulin domain
243 TSHRoncoprotein30.3335.4007tm_1 (PF00001, IPR000276): 7 transmembrane receptor (rhodopsin family)
LRR_5 (PF13306, IPR026906): Leucine rich repeats (6 copies)
LRR_8 (PF13855, IPR001611): Leucine rich repeat
SSFA2_C (PF14723, IPR029326): Sperm-specific antigen 2 C-terminus
244 TTC1interactor70.38119.499TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
Fis1_TPR_C (PF14853, IPR028061): Fis1 C-terminal tetratricopeptide repeat
245 TTI1interactor80.4648.790Dopey_N (PF04118, IPR007249): Dopey, N-terminal
HEAT (PF02985, IPR000357): HEAT repeat
VHS (PF00790, IPR002014, SM00288): VHS domain
CLASP_N (PF12348, IPR024395): CLASP N terminal
246 TTRinteractor4020.570Transthyretin (PF00576, IPR023416, SM00095): HIUase/Transthyretin family
247 TUBA1Cprotein found in more fusions540.250473.468Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain
Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain
248 TUBA3Cinteractor120.5307.779Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain
Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain
249 TUBA4Ainteractor580.1691341.729Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain
Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain
250 TUBBprotein found in more fusions1160.1425001.588Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain
Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain
251 TUBB1interactor150.229117.550Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain
Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain
252 TUBB2Ainteractor400.218512.690Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain
Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain
253 TUBB2Binteractor300.237250.905Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain
Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain
254 TUBB3interactor570.1251540.246Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain
Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain
255 TUBB4Binteractor690.2051134.320Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain
Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain
256 TUBB6interactor250.267127.795Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain
Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain
257 TUBG1protein found in more fusions470.286570.143Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain
Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain
258 TUBGCP2interactor190.60222.868Spc97_Spc98 (PF04130, IPR007259): Spc97 / Spc98 family
zf-Tim10_DDP (PF02953, IPR004217): Tim10/DDP family zinc finger
259 TUBGCP3interactor180.59520.046Spc97_Spc98 (PF04130, IPR007259): Spc97 / Spc98 family
260 TUBGCP4interactor120.66725.217Spc97_Spc98 (PF04130, IPR007259): Spc97 / Spc98 family
261 TXNDC15interactor30.6670.143Thioredoxin (PF00085, IPR013766): Thioredoxin
262 U2AF1oncoprotein150.36230.757DUF1509 (PF07420, IPR010883): Protein of unknown function (DUF1509)
KMP11 (PF03037, IPR004132): Kinetoplastid membrane protein 11
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
zf-CCCH (PF00642, IPR000571): Zinc finger C-x8-C-x5-C-x3-H type (and similar)
263 UBAC2interactor50.70012.787Rhomboid (PF01694, IPR022764): Rhomboid family
UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
264 UBASH3Binteractor230.42074.965His_Phos_1 (PF00300, IPR013078, SM00855): Histidine phosphatase superfamily (branch 1)
UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
2_5_RNA_ligase2 (PF13563): 2'-5' RNA ligase superfamily
SH3_9 (PF14604, IPR001452): Variant SH3 domain
265 UBCprotein found in more fusions720.1391921.066ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
266 UBE2D3interactor160.229111.016UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
267 UBL4Ainteractor240.37096.421ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
268 UCHL1suppressor150.42958.029Peptidase_C12 (PF01088, IPR001578): Ubiquitin carboxyl-terminal hydrolase, family 1
269 USP32oncoprotein21.0000UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase
DUSP (PF06337, IPR006615, SM00695): DUSP domain
EF-hand_6 (PF13405, IPR002048): EF-hand domain
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
Ubiquitin_3 (PF14836, IPR028135): Ubiquitin-like domain
270 USP37interactor80.4768.865UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase
UCH_N (PF16674, IPR032069): N-terminal of ubiquitin carboxyl-terminal hydrolase 37
271 USP50interactor50.9000.167UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase
272 VAV1oncoprotein100.53335.810PH (PF00169, IPR001849, SM00233): PH domain
RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain
SH2 (PF00017, IPR000980, SM00252): SH2 domain
C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain)
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
CAMSAP_CH (PF11971, IPR022613): CAMSAP CH domain
273 VCAM1interactor310.275183.136C2-set (PF05790, IPR008424): Immunoglobulin C2-set domain
I-set (PF07679, IPR013098): Immunoglobulin I-set domain
ig (PF00047, IPR013151, SM00409): Immunoglobulin domain
V-set (PF07686, IPR013106): Immunoglobulin V-set domain
Ig_3 (PF13927): Immunoglobulin domain
274 VCLoncoprotein130.48524.250Vinculin (PF01044, IPR006077): Vinculin family
275 VDAC1interactor120.21258.512Porin_3 (PF01459, IPR027246): Eukaryotic porin
276 VHLsuppressor210.347152.555Trypan_PARP (PF05887, IPR008882): Procyclic acidic repetitive protein (PARP)
VHL (PF01847, IPR022772): VHL beta domain
VHL_C (PF17211): VHL box domain
277 VSX1interactor21.0000Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
278 XPO1interactor650.1591281.091CRM1_C (PF08767, IPR014877, SM01102): CRM1 C terminal
Hydrolase_3 (PF08282, IPR023214): haloacid dehalogenase-like hydrolase
IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain
Xpo1 (PF08389, IPR013598): Exportin 1-like protein
Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region
279 YWHAEoncoprotein410.316297.94314-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
280 YWHAQinteractor480.251478.80814-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
281 ZAP70interactor120.67385.681Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
SH2 (PF00017, IPR000980, SM00252): SH2 domain
282 ZBTB1interactor100.40031.710BTB (PF00651, IPR013069, SM00225): BTB/POZ domain
zf-BED (PF02892, IPR003656, SM00614): BED zinc finger
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-C2H2_jaz (PF12171, IPR022755): Zinc-finger double-stranded RNA-binding
zf-C2H2_2 (PF12756, IPR015880): C2H2 type zinc-finger (2 copies)
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger
283 ZMYM2oncoprotein60.2679.648YHS (PF04945, IPR007029): YHS domain
zf-FCS (PF06467, IPR010507): MYM-type Zinc finger with FCS sequence motif
DUF3504 (PF12012, IPR021893): Domain of unknown function (DUF3504)
SOBP (PF15279, IPR026092): Sine oculis-binding protein

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