Find Fusion Network

Visualization interactions

Powered by Cytoscape Web for: parental proteins TRAF6 (from a repository: Fri Nov 11 22:44:20 2016)

Examples AFF1 MLL ACTN4 + MLLAFF1 + MLLALK + MSNALK + TFGALK + TPM3ALK + TPM4ASXL2 + KAT6AATF1 + FUSBCR + ABL1BCR + FGFR1CCND1 + TACSTD2CD74 + ROS1CDK6 + MLLCOL1A1 + PDGFBCREB3L2 + PPARGCREB3L2 + FUSCREBBP + KAT6ADAZAP1 + MEF2DELL + MLLEPS15 + MLLERG + EWSR1ERG + FUSERG + TMPRSS2ETV5 + TMPRSS2ETV6 + ABL1ETV6 + NTRK3ETV6 + PAX5EWSR1 + FLI1EWSR1 + WT1FOXO1 + PAX3FOXP1 + PAX5FRYL + MLLGAS7 + MLLGMPS + MLLGOLGA5 + RETHOOK3 + RETHOXC13 + NUP98HOXD13 + NUP98MECOM + RUNX1MKL1 + RBM15MLL + MLLT1MLL + MLLT4MLL + MLLT10MLL + PICALMMLLT10 + PICALMNCOA1 + PAX3NIN + PDGFRBNPM1 + RARANRG1 + ODZ4NTRK1 + TFGNUMA1 + RARANUP98 + PHF23PAX5 + ZNF521PBX1 + TCF3RET + TRIM27ROS1 + SLC34A2PML + RARAPRKAR1A + RARAPRKAR1A + RETRUNX1 + RUNX1T1RUNX1 + SH3D19	Cytoscape Web will replace the contents your graph	PPI Properties: Click on nodes or edges
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Statistics and Network structure information

Statistic of PPI Value(s) The number of interactors (fusion and proteins) 248 The number (and %) of the onco-proteins 73 (29.44 %) The number (and %) of the tumor suppressors 40 (16.13 %) Total number of binary PPIs (saturation %) 1777 (5.80 %) The number (and %) of affected PPIs 248 (13.96 %) The number of possible different fusions 49 PPI diameter 2 PPI radius 1 The average degree of PPI 13.274 Assortativity coefficient -0.2323 The network average Clustering coefficient 0.474 The number (and %) of a zero Clustering coefficients 8 (3.23 %) The number (and %) of a zero Betweenness Centrality 30 (12.10 %)

ACTIVE INTERACTORS

List of the fusions
PPI for parental proteins: TRAF6	All fusions
Proteins found in more fusions	PSMC2 (see 1 fusions); UBE2O (see 1 fusions); SYK (see 1 fusions); TRIM25 (see 2 fusions); RNF114 (see 1 fusions); FYN (see 1 fusions); PINK1 (see 3 fusions); SNAP29 (see 1 fusions); UBE2N (see 1 fusions); TNFRSF1A (see 2 fusions); WWP1 (see 1 fusions); RUNX1 (see 1 fusions); UBE2D2 (see 2 fusions); EIF2AK2 (see 1 fusions); UBE2L3/BIRC2 (see 1 fusions); TRAF4 (see 1 fusions); ULK1 (see 2 fusions); HTT (see 1 fusions); IKBKB (see 2 fusions); MAP3K5 (see 1 fusions); UBE2E1 (see 2 fusions); UBC (see 1 fusions); MTOR (see 1 fusions); ZMYND11 (see 1 fusions); TAB2 (see 1 fusions); TRAF6 (see 1 fusions); APP (see 4 fusions); MCL1 (see 2 fusions); MCM7 (see 2 fusions); VCP (see 4 fusions); TICAM1 (see 1 fusions); JAK2 (see 3 fusions); SQSTM1 (see 5 fusions); USP1 (see 1 fusions); MAPT (see 1 fusions); STAT3 (see 2 fusions); MALT1 (see 1 fusions); CD40 (see 2 fusions); USP20 (see 1 fusions); RANBP9 (see 2 fusions); STUB1 (see 1 fusions); RACK1 (see 3 fusions); USP10 (see 1 fusions); TRAF6/GANAB (see 1 fusions); MAP3K7 (see 7 fusions); DDB1 (see 2 fusions); RPTOR (see 3 fusions); CBLB (see 3 fusions);

List of active interactors

#	Name	Type	Number of PPI (degree)	Clustering Coefficient	Betweenness Centrality	Domains (Pfam, InterPro, SMART): description
1	TRAF6	parental protein	248	0.046	42317.913	SlyX (PF04102, IPR007236): SlyX zf-TRAF (PF02176, IPR001293): TRAF-type zinc finger zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
2	AJUBA	oncoprotein	3	1.000	0	LIM (PF00412, IPR001781, SM00132): LIM domain
3	AKT1	oncoprotein	35	0.225	256.507	PH (PF00169, IPR001849, SM00233): PH domain Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
4	AMBRA1	interactor	16	0.442	42.387	Acyl_CoA_thio (PF02551, IPR025652): Acyl-CoA thioesterase eIF2A (PF08662, IPR013979): Eukaryotic translation initiation factor eIF2A WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Spt20 (PF12090, IPR021950): Spt20 family ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
5	APP	protein found in more fusions	54	0.076	1056.961	APP_N (PF02177, IPR015849, SM00006): Amyloid A4 N-terminal heparin-binding Beta-APP (PF03494, IPR013803): Beta-amyloid peptide (beta-APP) BUD22 (PF09073, IPR015158): BUD22 IncA (PF04156, IPR007285): IncA protein Kunitz_BPTI (PF00014, IPR002223, SM00131): Kunitz/Bovine pancreatic trypsin inhibitor domain APP_amyloid (PF10515, IPR019543): beta-amyloid precursor protein C-terminus APP_Cu_bd (PF12924, IPR011178): Copper-binding of amyloid precursor, CuBD APP_E2 (PF12925, IPR024329): E2 domain of amyloid precursor protein
6	APPL1	interactor	11	0.333	19.763	ATP-synt_E (PF05680, IPR008386): ATP synthase E chain Fzo_mitofusin (PF04799, IPR006884): fzo-like conserved region PH (PF00169, IPR001849, SM00233): PH domain PID (PF00640, IPR006020, SM00462): Phosphotyrosine interaction domain (PTB/PID) BAR_3 (PF16746): BAR domain of APPL family
7	ARRB1	interactor	13	0.436	22.901	Arrestin_C (PF02752, IPR011022, SM01017): Arrestin (or S-antigen), C-terminal domain Arrestin_N (PF00339, IPR011021): Arrestin (or S-antigen), N-terminal domain
8	ARRB2	interactor	18	0.346	55.540	Arrestin_C (PF02752, IPR011022, SM01017): Arrestin (or S-antigen), C-terminal domain Arrestin_N (PF00339, IPR011021): Arrestin (or S-antigen), N-terminal domain
9	ASXL2	interactor	3	0.667	0.095	DUF1180 (PF06679, IPR009565): Protein of unknown function (DUF1180) K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain HARE-HTH (PF05066, IPR007759): HB1, ASXL, restriction endonuclease HTH domain ASXH (PF13919, IPR028020): Asx homology domain PHD_3 (PF13922, IPR026905): PHD domain of transcriptional enhancer, Asx DUF4551 (PF15087, IPR027878): Protein of unknown function (DUF4551)
10	ATM	suppressor	8	0.476	5.983	FAT (PF02259, IPR003151): FAT domain FATC (PF02260, IPR003152): FATC domain HEAT (PF02985, IPR000357): HEAT repeat PI3_PI4_kinase (PF00454, IPR000403, SM00146): Phosphatidylinositol 3- and 4-kinase TAN (PF11640, IPR021668): Telomere-length maintenance and DNA damage repair ANAPC5 (PF12862, IPR026000): Anaphase-promoting complex subunit 5
11	ATXN3	interactor	12	0.455	15.656	Josephin (PF02099, IPR006155): Josephin UIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif SUIM_assoc (PF16619): Unstructured region C-term to UIM in Ataxin3
12	BCL10	suppressor	19	0.477	28.153	CARD (PF00619, IPR001315, SM00114): Caspase recruitment domain
13	BECN1	suppressor	13	0.318	30.817	APG6 (PF04111, IPR007243): Autophagy protein Apg6 Ima1_N (PF09779, IPR018617): Ima1 N-terminal domain BH3 (PF15285, IPR029318): Beclin-1 BH3 domain, Bcl-2-interacting
14	BIRC2	oncoprotein	28	0.385	82.049	BIR (PF00653, IPR001370, SM00238): Inhibitor of Apoptosis domain CARD (PF00619, IPR001315, SM00114): Caspase recruitment domain zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
15	BIRC3	oncoprotein	31	0.372	113.632	BIR (PF00653, IPR001370, SM00238): Inhibitor of Apoptosis domain CARD (PF00619, IPR001315, SM00114): Caspase recruitment domain zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
16	BMPR1B	interactor	7	0.533	2.037	Activin_recp (PF01064, IPR000472): Activin types I and II receptor domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase TGF_beta_GS (PF08515, IPR003605, SM00467): Transforming growth factor beta type I GS-motif
17	CALCOCO2	interactor	13	0.394	25.008	bZIP_1 (PF00170, IPR004827): bZIP transcription factor CALCOCO1 (PF07888, IPR012852): Calcium binding and coiled-coil domain (CALCOCO1) like DUF641 (PF04859, IPR006943): Plant protein of unknown function (DUF641) OmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like) Jnk-SapK_ap_N (PF09744, IPR019143): JNK_SAPK-associated protein-1 GAS (PF13851, IPR025593): Growth-arrest specific micro-tubule binding zf-C2H2_4 (PF13894): C2H2-type zinc finger
18	CANX	interactor	6	0.600	3.567	Calreticulin (PF00262, IPR001580): Calreticulin family DUF1510 (PF07423, IPR009988): Protein of unknown function (DUF1510) TRAP_alpha (PF03896, IPR005595): Translocon-associated protein (TRAP), alpha subunit
19	CARD11	oncoprotein	12	0.527	10.324	CARD (PF00619, IPR001315, SM00114): Caspase recruitment domain DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664) Cnn_1N (PF07989, IPR012943): Centrosomin N-terminal motif 1 PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) zf-C4H2 (PF10146, IPR018482): Zinc finger-containing protein Guanylate_kin (PF00625, IPR008145, SM00072): Guanylate kinase DUF3450 (PF11932, IPR016866): Protein of unknown function (DUF3450)
20	CASP4	interactor	4	0.667	0.889	CARD (PF00619, IPR001315, SM00114): Caspase recruitment domain Peptidase_C14 (PF00656, IPR011600): Caspase domain
21	CASP8	suppressor	21	0.395	60.483	DED (PF01335, IPR001875, SM00031): Death effector domain Peptidase_C14 (PF00656, IPR011600): Caspase domain
22	CBLB	oncoprotein	12	0.309	21.932	Cbl_N (PF02262, IPR003153): CBL proto-oncogene N-terminal domain 1 Cbl_N2 (PF02761, IPR014741): CBL proto-oncogene N-terminus, EF hand-like domain Cbl_N3 (PF02762, IPR014742): CBL proto-oncogene N-terminus, SH2-like domain UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain Prok-RING_4 (PF14447): Prokaryotic RING finger family 4 PRIMA1 (PF16101): Proline-rich membrane anchor 1
23	CD40	protein found in more fusions	17	0.392	35.705	Glycophorin_A (PF01102, IPR001195): Glycophorin A TNFR_c6 (PF00020, IPR001368, SM00208): TNFR/NGFR cysteine-rich region
24	CHUK	suppressor	38	0.275	229.495	Pkinase (PF00069, IPR000719): Protein kinase domain IKKbetaNEMObind (PF12179, IPR022007): I-kappa-kinase-beta NEMO binding domain
25	CSNK1G1	interactor	2	1.000	0	Pkinase (PF00069, IPR000719): Protein kinase domain CK1gamma_C (PF12605, IPR022247): Casein kinase 1 gamma C terminal
26	CTPS1	interactor	5	0.667	0.750	CTP_synth_N (PF06418, IPR017456): CTP synthase N-terminus GATase (PF00117, IPR017926): Glutamine amidotransferase class-I
27	CYCS	interactor	2	1.000	0	Cytochrom_C (PF00034, IPR003088): Cytochrome c
28	CYLD	suppressor	13	0.436	19.236	CAP_GLY (PF01302, IPR000938, SM01052): CAP-Gly domain UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase zf-HIT (PF04438, IPR007529): HIT zinc finger CYLD_phos_site (PF16607): Phosphorylation region of CYLD, unstructured
29	DCBLD2	interactor	1	0	0	CUB (PF00431, IPR000859, SM00042): CUB domain LCCL (PF03815, IPR004043, SM00603): LCCL domain Syndecan (PF01034, IPR027789): Syndecan domain F5_F8_type_C (PF00754, IPR000421, SM00231): F5/8 type C domain
30	DDB1	protein found in more fusions	12	0.436	21.208	CPSF_A (PF03178, IPR004871): CPSF A subunit region MMS1_N (PF10433): Mono-functional DNA-alkylating methyl methanesulfonate N-term
31	DDX3X	suppressor	7	0.381	6.515	DEAD (PF00270, IPR011545): DEAD/DEAH box helicase DUF755 (PF05501, IPR008474): Domain of unknown function (DUF755) Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
32	DEUP1	suppressor	3	1.000	0	APG6 (PF04111, IPR007243): Autophagy protein Apg6 TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein bZIP_2 (PF07716, IPR004827, SM00338): Basic region leucine zipper Lebercilin (PF15619, IPR028933): Ciliary protein causing Leber congenital amaurosis disease CEP63 (PF17045, IPR031470): Centrosomal protein of 63 kDa
33	EDA2R	suppressor	4	0.667	1.667	Ephrin_rec_like (PF07699, IPR011641): Putative ephrin-receptor like TNFR_c6 (PF00020, IPR001368, SM00208): TNFR/NGFR cysteine-rich region
34	EDARADD	interactor	7	0.600	2.583	Death (PF00531, IPR000488, SM00005): Death domain SCO1-SenC (PF02630, IPR003782): SCO1/SenC
35	EIF2AK2	oncoprotein	13	0.439	17.123	dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif Pkinase (PF00069, IPR000719): Protein kinase domain
36	EIF4E2	interactor	4	0.500	1.619	IF4E (PF01652, IPR001040): Eukaryotic initiation factor 4E
37	EPPK1	interactor	4	0.833	0.333	DUF1840 (PF08895, IPR014991): Domain of unknown function (DUF1840) HupF_HypC (PF01455, IPR001109): HupF/HypC family Plectin (PF00681, IPR001101, SM00250): Plectin repeat RPA_interact_N (PF14766, IPR028158): Replication protein A interacting N-terminal
38	ERN1	interactor	8	0.476	4.882	Pkinase (PF00069, IPR000719): Protein kinase domain PQQ (PF01011, IPR002372, SM00564): PQQ enzyme repeat Ribonuc_2-5A (PF06479, IPR010513): Ribonuclease 2-5A CytochromB561_N (PF09786, IPR019176): Cytochrome B561, N terminal PQQ_2 (PF13360, IPR002372): PQQ-like domain
39	ESR1	suppressor	31	0.182	237.673	Oest_recep (PF02159, IPR001292): Oestrogen receptor zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor ESR1_C (PF12743, IPR024736): Oestrogen-type nuclear receptor final C-terminal
40	FHL2	oncoprotein	11	0.333	19.871	LIM (PF00412, IPR001781, SM00132): LIM domain zf-ribbon_3 (PF13248): zinc-ribbon domain
41	FOXG1	oncoprotein	2	1.000	0	SelP_N (PF04592, IPR007671): Selenoprotein P, N terminal region SPX (PF03105, IPR004331): SPX domain DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360) Forkhead (PF00250, IPR001766, SM00339): Forkhead domain
42	FYN	oncoprotein	16	0.305	49.344	Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
43	GANAB	suppressor	3	1.000	0	Glyco_hydro_31 (PF01055, IPR000322): Glycosyl hydrolases family 31 Gal_mutarotas_2 (PF13802, IPR025887): Galactose mutarotase-like DUF5110 (PF17137): Domain of unknown function (DUF5110)
44	GTF2I	interactor	10	0.289	21.167	GTF2I (PF02946, IPR004212): GTF2I-like repeat
45	HIF1A	suppressor	19	0.234	82.706	Dicty_REP (PF05086, IPR007778): Dictyostelium (Slime Mold) REP protein HIF-1a_CTAD (PF08778, IPR014887): HIF-1 alpha C terminal transactivation domain HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain PAS (PF00989, IPR013767, SM00091): PAS fold PAS_3 (PF08447, IPR013655): PAS fold HIF-1 (PF11413, IPR021537): Hypoxia-inducible factor-1
46	HSD17B10	interactor	8	0.321	9.318	adh_short (PF00106, IPR002198): short chain dehydrogenase
47	HSPA4	interactor	32	0.228	227.250	Herpes_ICP4_N (PF03584, IPR005206): Herpesvirus ICP4-like protein N-terminal region HSP70 (PF00012, IPR013126): Hsp70 protein TP53IP5 (PF15331, IPR029290): Cellular tumour antigen p53-inducible 5
48	HSPB2	interactor	6	0.400	2.633	Crystallin (PF00525, IPR003090): Alpha crystallin A chain, N terminal HSP20 (PF00011, IPR002068): Hsp20/alpha crystallin family
49	HTT	protein found in more fusions	10	0.389	10.976	HEAT (PF02985, IPR000357): HEAT repeat SPX (PF03105, IPR004331): SPX domain TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit DUF3652 (PF12372, IPR024613): Huntingtin protein region Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region HEAT_EZ (PF13513): HEAT-like repeat HEAT_2 (PF13646): HEAT repeats
50	IARS	interactor	7	0.524	5.646	Anticodon_1 (PF08264, IPR013155): Anticodon-binding domain of tRNA tRNA-synt_1 (PF00133, IPR002300): tRNA synthetases class I (I, L, M and V)
51	IFIT3	interactor	9	0.357	13.982	TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat TPR_10 (PF13374, IPR011990): Tetratricopeptide repeat TPR_12 (PF13424): Tetratricopeptide repeat TPR_17 (PF13431): Tetratricopeptide repeat TPR_19 (PF14559): Tetratricopeptide repeat
52	IKBKB	protein found in more fusions	33	0.284	191.506	FliT (PF05400, IPR008622): Flagellar protein FliT Glyco_hydro_65m (PF03632, IPR005195): Glycosyl hydrolase family 65 central catalytic domain Pkinase (PF00069, IPR000719): Protein kinase domain SlyX (PF04102, IPR007236): SlyX ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family IKKbetaNEMObind (PF12179, IPR022007): I-kappa-kinase-beta NEMO binding domain
53	IKBKG	interactor	53	0.201	652.655	CENP-H (PF05837, IPR008426): Centromere protein H (CENP-H) DUF725 (PF05267, IPR007931): Protein of unknown function (DUF725) NEMO (PF11577, IPR021063): NF-kappa-B essential modulator NEMO LLC1 (PF14945, IPR020339): Normal lung function maintenance, Low in Lung Cancer 1 protein CC2-LZ (PF16516, IPR032419): Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator
54	IL17A	suppressor	4	1.000	0	IL17 (PF06083, IPR010345): Interleukin-17
55	IL17RA	interactor	5	0.800	1.333	SEFIR (PF08357, IPR013568): SEFIR domain IL17R_fnIII_D1 (PF16556, IPR032356): Interleukin-17 receptor, fibronectin-III-like domain 1 IL17R_fnIII_D2 (PF16578): Interleukin 17 receptor D
56	IL1R1	interactor	9	0.583	8.017	TIR (PF01582, IPR000157, SM00255): TIR domain Ig_2 (PF13895, IPR007110): Immunoglobulin domain Ig_3 (PF13927): Immunoglobulin domain
57	IL1RL1	interactor	5	0.700	1.100	I-set (PF07679, IPR013098): Immunoglobulin I-set domain TIR (PF01582, IPR000157, SM00255): TIR domain Ig_2 (PF13895, IPR007110): Immunoglobulin domain Ig_3 (PF13927): Immunoglobulin domain
58	IRAK1	interactor	39	0.203	372.595	Death (PF00531, IPR000488, SM00005): Death domain Pkinase (PF00069, IPR000719): Protein kinase domain
59	IRAK2	oncoprotein	16	0.350	48.736	Death (PF00531, IPR000488, SM00005): Death domain Pkinase (PF00069, IPR000719): Protein kinase domain
60	IRAK3	interactor	5	1.000	0	Death (PF00531, IPR000488, SM00005): Death domain Pkinase (PF00069, IPR000719): Protein kinase domain
61	IRAK4	interactor	14	0.462	22.688	Death (PF00531, IPR000488, SM00005): Death domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
62	IRF3	suppressor	13	0.348	26.749	IRF (PF00605, IPR001346, SM00348): Interferon regulatory factor transcription factor IRF-3 (PF10401, IPR019471): Interferon-regulatory factor 3
63	IRF4	suppressor	5	0.600	1.115	IRF (PF00605, IPR001346, SM00348): Interferon regulatory factor transcription factor IRF-3 (PF10401, IPR019471): Interferon-regulatory factor 3
64	IRF5	suppressor	7	0.467	2.910	IRF (PF00605, IPR001346, SM00348): Interferon regulatory factor transcription factor IRF-3 (PF10401, IPR019471): Interferon-regulatory factor 3
65	IRF7	interactor	8	0.476	4.278	IRF (PF00605, IPR001346, SM00348): Interferon regulatory factor transcription factor IRF-3 (PF10401, IPR019471): Interferon-regulatory factor 3
66	IRF8	suppressor	3	1.000	0	IRF (PF00605, IPR001346, SM00348): Interferon regulatory factor transcription factor IRF-3 (PF10401, IPR019471): Interferon-regulatory factor 3
67	ITCH	interactor	24	0.213	111.396	C2 (PF00168, IPR000008, SM00239): C2 domain WW (PF00397, IPR001202, SM00456): WW domain HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
68	JAK2	oncoprotein	11	0.444	15.221	FERM_M (PF00373, IPR019748): FERM central domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain
69	KCNQ1	interactor	3	0.667	0.500	Ion_trans (PF00520, IPR005821): Ion transport protein KCNQ_channel (PF03520, IPR013821): KCNQ voltage-gated potassium channel Sensor (PF13796, IPR025828): Putative sensor
70	KIR2DL4	interactor	1	0	0	ig (PF00047, IPR013151, SM00409): Immunoglobulin domain SVM_signal (PF12113, IPR021970): SVM protein signal sequence
71	KMT2E	interactor	5	0.400	3.567	CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal PHD (PF00628, IPR019787, SM00249): PHD-finger SET (PF00856, IPR001214, SM00317): SET domain MSA-2c (PF12238, IPR021060): Merozoite surface antigen 2c DUF4124 (PF13511, IPR025392): Domain of unknown function (DUF4124) PHD_3 (PF13922, IPR026905): PHD domain of transcriptional enhancer, Asx DUF4666 (PF15697, IPR031421): Domain of unknown function (DUF4666) PRIMA1 (PF16101): Proline-rich membrane anchor 1
72	KRAS	oncoprotein	13	0.242	38.008	Ras (PF00071, IPR001806, SM00173): Ras family
73	LAT	interactor	3	1.000	0	LAT (PF15234, IPR008359): Linker for activation of T-cells
74	LGMN	interactor	1	0	0	Peptidase_C13 (PF01650, IPR001096): Peptidase C13 family
75	LIMD1	suppressor	4	0.667	0.250	LIM (PF00412, IPR001781, SM00132): LIM domain
76	MAGEE2	interactor	2	1.000	0	MAGE (PF01454, IPR002190): MAGE family
77	MALT1	oncoprotein	14	0.590	8.538	Peptidase_C14 (PF00656, IPR011600): Caspase domain V-set (PF07686, IPR013106): Immunoglobulin V-set domain Ig_2 (PF13895, IPR007110): Immunoglobulin domain Ig_3 (PF13927): Immunoglobulin domain
78	MAP2K6	interactor	5	0.700	1.833	Pkinase (PF00069, IPR000719): Protein kinase domain
79	MAP3K11	interactor	9	0.714	1.841	APG6 (PF04111, IPR007243): Autophagy protein Apg6 Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH3_9 (PF14604, IPR001452): Variant SH3 domain
80	MAP3K14	interactor	16	0.514	18.462	Pkinase (PF00069, IPR000719): Protein kinase domain
81	MAP3K3	oncoprotein	12	0.400	12.169	PB1 (PF00564, IPR000270, SM00666): PB1 domain Pkinase (PF00069, IPR000719): Protein kinase domain
82	MAP3K5	oncoprotein	22	0.271	91.155	Pkinase (PF00069, IPR000719): Protein kinase domain DUF4071 (PF13281, IPR025136): Domain of unknown function (DUF4071)
83	MAP3K7	oncoprotein	51	0.182	642.088	Mnd1 (PF03962, IPR005647): Mnd1 family Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
84	MAP3K8	suppressor	7	0.667	1.700	Pkinase (PF00069, IPR000719): Protein kinase domain IML1 (PF12257, IPR027244): Vacuolar membrane-associated protein Iml1
85	MAPT	protein found in more fusions	15	0.484	22.408	Tubulin-binding (PF00418, IPR001084): Tau and MAP protein, tubulin-binding repeat
86	MARCH5	interactor	10	0.306	7.573	DUF2517 (PF10725, IPR019663): Protein of unknown function (DUF2517) RINGv (PF12906, IPR011016, SM00744): RING-variant domain
87	MAST2	oncoprotein	3	0.667	0.182	DUF1908 (PF08926, IPR015022): Domain of unknown function (DUF1908) PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) Pkinase (PF00069, IPR000719): Protein kinase domain
88	MAVS	interactor	28	0.225	166.949	Ice_nucleation (PF00818, IPR000258): Ice nucleation protein repeat CARD_2 (PF16739, IPR031964): Caspase recruitment domain
89	MCL1	oncoprotein	6	0.500	3.233	Bcl-2 (PF00452, IPR026298): Apoptosis regulator proteins, Bcl-2 family
90	MCM7	protein found in more fusions	8	0.381	4.714	MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family MCM_N (PF14551, IPR027925): MCM N-terminal domain MCM_OB (PF17207): MCM OB domain
91	MEOX2	interactor	4	0.500	3.000	Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
92	MSR1	interactor	1	0	0	bZIP_1 (PF00170, IPR004827): bZIP transcription factor Collagen (PF01391, IPR008160): Collagen triple helix repeat (20 copies) Macscav_rec (PF03523, IPR003543): Macrophage scavenger receptor Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein SRCR (PF00530, IPR001190): Scavenger receptor cysteine-rich domain AATF-Che1 (PF13339, IPR025160): Apoptosis antagonizing transcription factor
93	MTHFD1	interactor	4	0.667	0.297	FTHFS (PF01268, IPR000559): Formate--tetrahydrofolate ligase THF_DHG_CYH (PF00763, IPR020630): Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C (PF02882, IPR020631): Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain
94	MTOR	oncoprotein	18	0.382	40.572	DUF1104 (PF06518, IPR009488): Protein of unknown function (DUF1104) EPSP_synthase (PF00275, IPR001986): EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) FAT (PF02259, IPR003151): FAT domain FATC (PF02260, IPR003152): FATC domain HEAT (PF02985, IPR000357): HEAT repeat FRB_dom (PF08771, IPR009076): FKBP12-rapamycin binding domain V-ATPase_H_N (PF03224, IPR004908): V-ATPase subunit H PI3_PI4_kinase (PF00454, IPR000403, SM00146): Phosphatidylinositol 3- and 4-kinase DUF3385 (PF11865, IPR024585): Domain of unknown function (DUF3385) HEAT_EZ (PF13513): HEAT-like repeat HEAT_2 (PF13646): HEAT repeats TPR_19 (PF14559): Tetratricopeptide repeat
95	MUS81	suppressor	3	0.667	0.333	ERCC4 (PF02732, IPR006166, SM00891): ERCC4 domain MutL (PF13941, IPR006230): MutL protein HHH_8 (PF14716, IPR010996): Helix-hairpin-helix domain
96	MYB	oncoprotein	5	0.500	3.500	Cmyb_C (PF09316, IPR015395): C-myb, C-terminal LMSTEN (PF07988, IPR012642): LMSTEN motif Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
97	MYD88	oncoprotein	27	0.218	170.873	Death (PF00531, IPR000488, SM00005): Death domain TIR (PF01582, IPR000157, SM00255): TIR domain
98	NASP	interactor	4	1.000	0	Vfa1 (PF08432, IPR013640): AAA-ATPase Vps4-associated protein 1 DUF913 (PF06025, IPR010314): Domain of Unknown Function (DUF913) SlyX (PF04102, IPR007236): SlyX TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat TraV (PF09676, IPR014118): Type IV conjugative transfer system lipoprotein (TraV) SHNi-TPR (PF10516, IPR019544): SHNi-TPR XhlA (PF10779, IPR019715): Haemolysin XhlA TPR_8 (PF13181, IPR019734): Tetratricopeptide repeat CCSAP (PF15748, IPR029774): Centriole, cilia and spindle-associated MAP17 (PF15807, IPR031627): Membrane-associated protein 117 kDa, PDZK1-interacting protein 1
99	NFATC2IP	interactor	5	0.600	1.951	Rad60-SLD (PF11976, IPR022617): Ubiquitin-2 like Rad60 SUMO-like FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
100	NGFR	suppressor	11	0.489	8.776	LHC (PF00556, IPR000066): Antenna complex alpha/beta subunit
101	NLRC3	interactor	1	0	0	NACHT (PF05729): NACHT domain LRR_6 (PF13516, IPR001611): Leucine Rich repeat LRR_8 (PF13855, IPR001611): Leucine rich repeat
102	NLRX1	interactor	4	0.667	0.900	NACHT (PF05729): NACHT domain LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies) AAA_16 (PF13191): AAA ATPase domain AAA_22 (PF13401, IPR003593): AAA domain LRR_6 (PF13516, IPR001611): Leucine Rich repeat
103	NOD2	interactor	14	0.590	8.426	CARD (PF00619, IPR001315, SM00114): Caspase recruitment domain NACHT (PF05729): NACHT domain LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies) LRR_6 (PF13516, IPR001611): Leucine Rich repeat
104	NR0B2	suppressor	2	1.000	0	Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
105	NR2C2	suppressor	10	0.361	15.486	Flagellin_N (PF00669, IPR001029): Bacterial flagellin N-terminal helical region zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
106	NTRK1	oncoprotein	55	0.101	1017.907	I-set (PF07679, IPR013098): Immunoglobulin I-set domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase LRR_8 (PF13855, IPR001611): Leucine rich repeat TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain
107	NTRK2	oncoprotein	4	0.500	1.900	I-set (PF07679, IPR013098): Immunoglobulin I-set domain LRRNT (PF01462, IPR000372, SM00013): Leucine rich repeat N-terminal domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase LRR_8 (PF13855, IPR001611): Leucine rich repeat TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain
108	NUMBL	interactor	3	0.667	0.333	DUF1932 (PF09130, IPR015814): Domain of unknown function (DUF1932) NumbF (PF06311, IPR010449): NUMB domain PID (PF00640, IPR006020, SM00462): Phosphotyrosine interaction domain (PTB/PID) DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360) DUF2722 (PF10846, IPR021216): Protein of unknown function (DUF2722) SUIM_assoc (PF16619): Unstructured region C-term to UIM in Ataxin3
109	OTUB1	interactor	26	0.231	147.369	Peptidase_C65 (PF10275, IPR019400): Peptidase C65 Otubain
110	OTUB2	interactor	10	0.444	13.560	Peptidase_C65 (PF10275, IPR019400): Peptidase C65 Otubain
111	OTUD7A	interactor	2	1.000	0	OTU (PF02338, IPR003323): OTU-like cysteine protease Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein zf-A20 (PF01754, IPR002653, SM00259): A20-like zinc finger UBA_4 (PF14555): UBA-like domain CCDC106 (PF15794, IPR031591): Coiled-coil domain-containing protein 106 AP3D1 (PF06375): AP-3 complex subunit delta-1
112	OTUD7B	interactor	4	0.500	0.956	OTU (PF02338, IPR003323): OTU-like cysteine protease zf-A20 (PF01754, IPR002653, SM00259): A20-like zinc finger UBA_4 (PF14555): UBA-like domain CCDC106 (PF15794, IPR031591): Coiled-coil domain-containing protein 106
113	PAICS	interactor	5	0.667	0.682	AIRC (PF00731, IPR000031, SM01001): AIR carboxylase SAICAR_synt (PF01259, IPR028923): SAICAR synthetase
114	PARK7	suppressor	11	0.378	15.644	DJ-1_PfpI (PF01965, IPR002818): DJ-1/PfpI family
115	PDLIM7	interactor	10	0.400	18.719	LIM (PF00412, IPR001781, SM00132): LIM domain PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) zinc_ribbon_10 (PF10058, IPR019273): Predicted integral membrane zinc-ribbon metal-binding protein DUF4749 (PF15936, IPR031847): Domain of unknown function (DUF4749)
116	PEBP1	suppressor	2	1.000	0	PBP (PF01161, IPR008914): Phosphatidylethanolamine-binding protein
117	PELI1	interactor	14	0.352	35.540	Pellino (PF04710, IPR006800): Pellino
118	PELI2	interactor	5	0.700	1.833	Pellino (PF04710, IPR006800): Pellino
119	PELI3	interactor	11	0.400	15.349	Pellino (PF04710, IPR006800): Pellino
120	PFAS	interactor	5	0.600	1.700	AIRS_C (PF02769, IPR010918): AIR synthase related protein, C-terminal domain GATase_5 (PF13507): CobB/CobQ-like glutamine amidotransferase domain
121	PINK1	protein found in more fusions	18	0.272	62.974	Pkinase (PF00069, IPR000719): Protein kinase domain
122	PLEKHF2	interactor	3	0.667	0.667	FYVE (PF01363, IPR000306, SM00064): FYVE zinc finger PH (PF00169, IPR001849, SM00233): PH domain
123	PLEKHO1	suppressor	5	0.500	1.008	PH (PF00169, IPR001849, SM00233): PH domain DUF3055 (PF11256, IPR021415): Protein of unknown function (DUF3055)
124	POLI	interactor	4	0.667	1.095	IMS (PF00817, IPR001126): impB/mucB/samB family Cdd1 (PF11731, IPR021725): Pathogenicity locus IMS_HHH (PF11798, IPR024728): IMS family HHH motif IMS_C (PF11799, IPR017961): impB/mucB/samB family C-terminal domain DUF4414 (PF14377, IPR025527): Domain of unknown function (DUF4414)
125	PPP1CC	oncoprotein	12	0.394	22.725	Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase STPPase_N (PF16891, IPR031675): Serine-threonine protein phosphatase N-terminal domain
126	PPP4C	interactor	4	0.500	1.952	Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase STPPase_N (PF16891, IPR031675): Serine-threonine protein phosphatase N-terminal domain
127	PPP4R1	interactor	4	0.500	1.833	HEAT (PF02985, IPR000357): HEAT repeat Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region HEAT_2 (PF13646): HEAT repeats WRNPLPNID (PF15017): Putative WW-binding domain and destruction box
128	PRKCZ	interactor	12	0.509	15.808	PB1 (PF00564, IPR000270, SM00666): PB1 domain Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain)
129	PSEN1	oncoprotein	11	0.289	21.767	Presenilin (PF01080, IPR001108): Presenilin LRRC37AB_C (PF14914, IPR029423): LRRC37A/B like protein 1 C-terminal domain
130	PSEN2	oncoprotein	6	0.700	1.833	Herpes_LMP1 (PF05297, IPR007961): Herpesvirus latent membrane protein 1 (LMP1) Presenilin (PF01080, IPR001108): Presenilin
131	PSMB5	interactor	14	0.626	17.494	Proteasome (PF00227, IPR001353): Proteasome subunit
132	PSMC1	interactor	16	0.567	30.599	AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA) AAA_3 (PF07726, IPR011703): ATPase family associated with various cellular activities (AAA) DivIC (PF04977, IPR007060): Septum formation initiator DUF815 (PF05673, IPR008533): Protein of unknown function (DUF815) Prot_ATP_ID_OB (PF16450, IPR032501): Proteasomal ATPase OB/ID domain
133	PSMC2	protein found in more fusions	19	0.523	36.361	AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA)
134	PSMC3	interactor	21	0.411	65.985	AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA) DUF3713 (PF12506, IPR022186): Protein of unknown function (DUF3713) JIP_LZII (PF16471, IPR032486): JNK-interacting protein leucine zipper II
135	PSMD1	interactor	14	0.626	16.730	PA26 (PF04636, IPR006730): PA26 p53-induced protein (sestrin) PC_rep (PF01851, IPR002015): Proteasome/cyclosome repeat HEAT_2 (PF13646): HEAT repeats
136	PSMD12	interactor	16	0.571	25.096	Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain PCI (PF01399, IPR000717, SM00088): PCI domain
137	PSMD13	interactor	12	0.803	4.375	Mitovir_RNA_pol (PF05919, IPR008686): Mitovirus RNA-dependent RNA polymerase PCI (PF01399, IPR000717, SM00088): PCI domain
138	PSMD3	interactor	12	0.818	3.233	Rpn3_C (PF08375, IPR013586): Proteasome regulatory subunit C-terminal TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat PCI (PF01399, IPR000717, SM00088): PCI domain Fis1_TPR_C (PF14853, IPR028061): Fis1 C-terminal tetratricopeptide repeat TSKS (PF15358, IPR028214): Testis-specific serine kinase substrate
139	PSMD7	interactor	14	0.648	18.027	JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg (PF13012, IPR024969): Maintenance of mitochondrial structure and function Auts2 (PF15336): Autism susceptibility gene 2 protein Coilin_N (PF15862, IPR031722): Coilin N-terminus
140	RACK1	suppressor	12	0.382	19.403	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
141	RANBP9	suppressor	15	0.341	36.227	Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator LisH (PF08513, IPR013720, SM00667): LisH SPRY (PF00622, IPR003877, SM00449): SPRY domain CLTH (PF10607, IPR024964): CTLH/CRA C-terminal to LisH motif domain
142	RBCK1	interactor	27	0.311	105.646	GAGA (PF09237, IPR015318): GAGA factor IBR (PF01485, IPR002867, SM00647): IBR domain, a half RING-finger domain ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger
143	RCAN1	interactor	4	0.667	1.200	Calcipressin (PF04847, IPR006931): Calcipressin
144	RIPK2	interactor	22	0.462	42.869	CARD (PF00619, IPR001315, SM00114): Caspase recruitment domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
145	RNF114	protein found in more fusions	12	0.364	16.701	zf-Di19 (PF05605, IPR008598): Drought induced 19 protein (Di19), zinc-binding HypA (PF01155, IPR000688): Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger zf-RING_4 (PF14570): RING/Ubox like zinc-binding domain
146	RNF166	interactor	9	0.250	12.832	zf-Di19 (PF05605, IPR008598): Drought induced 19 protein (Di19), zinc-binding zinc-ribbons_6 (PF07191, IPR010807): zinc-ribbons Rad50_zn_hook (PF04423, IPR007517): Rad50 zinc hook motif UIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif zinc_ribbon_2 (PF13240, IPR026870): zinc-ribbon domain zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger zf-RING_4 (PF14570): RING/Ubox like zinc-binding domain
147	RPTOR	protein found in more fusions	17	0.400	36.375	HEAT (PF02985, IPR000357): HEAT repeat WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1 ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain HEAT_2 (PF13646): HEAT repeats Raptor_N (PF14538, IPR029347): Raptor N-terminal CASPase like domain
148	RRAGC	interactor	4	1.000	0	Gtr1_RagA (PF04670, IPR006762): Gtr1/RagA G protein conserved region
149	RUNX1	suppressor	4	0.667	0.333	Runt (PF00853, IPR013524): Runt domain RunxI (PF08504, IPR013711): Runx inhibition domain DUF3037 (PF11236, IPR021398): Protein of unknown function (DUF3037)
150	RUSC1	interactor	4	0.667	0.321	RUN (PF02759, IPR004012, SM00593): RUN domain MAGE_N (PF12440, IPR021072): Melanoma associated antigen family N terminal SH3_9 (PF14604, IPR001452): Variant SH3 domain
151	SARM1	interactor	10	0.311	20.167	Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat Carb_kinase (PF01256, IPR000631): Carbohydrate kinase SAM_2 (PF07647, IPR011510): SAM domain (Sterile alpha motif) HEAT_2 (PF13646): HEAT repeats TIR_2 (PF13676, IPR000157): TIR domain
152	SDCBP	interactor	9	0.278	18.841	PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
153	SIGIRR	interactor	6	0.600	1.819	TIR (PF01582, IPR000157, SM00255): TIR domain Ig_3 (PF13927): Immunoglobulin domain
154	SMURF1	interactor	24	0.194	117.325	C2 (PF00168, IPR000008, SM00239): C2 domain WW (PF00397, IPR001202, SM00456): WW domain HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
155	SNAP29	protein found in more fusions	2	0	0	DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664) Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family V-SNARE_C (PF12352): Snare region anchored in the vesicle membrane C-terminus DUF5082 (PF16888, IPR031681): Domain of unknown function (DUF5082)
156	SNCA	interactor	18	0.375	47.342	Synuclein (PF01387, IPR001058): Synuclein
157	SOCS3	suppressor	6	0.533	3.848	SH2 (PF00017, IPR000980, SM00252): SH2 domain SOCS_box (PF07525, IPR001496): SOCS box
158	SPHK1	interactor	4	0.833	0.286	DAGK_cat (PF00781, IPR001206, SM00046): Diacylglycerol kinase catalytic domain
159	SPOP	suppressor	8	0.333	6.650	BACK (PF07707, IPR011705, SM00875): BTB And C-terminal Kelch BTB (PF00651, IPR013069, SM00225): BTB/POZ domain MATH (PF00917, IPR002083, SM00061): MATH domain
160	SQSTM1	oncoprotein	38	0.164	401.225	PB1 (PF00564, IPR000270, SM00666): PB1 domain ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type UBA_5 (PF16577, IPR015940): UBA domain
161	SRC	oncoprotein	25	0.319	95.546	Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
162	STAMBP	interactor	6	0.600	2.843	USP8_dimer (PF08969, IPR015063): USP8 dimerisation domain JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease DUF3526 (PF12040, IPR021913): Domain of unknown function (DUF3526)
163	STAT3	suppressor	18	0.272	61.901	SH2 (PF00017, IPR000980, SM00252): SH2 domain STAT_alpha (PF01017, IPR013800): STAT protein, all-alpha domain STAT_bind (PF02864, IPR013801): STAT protein, DNA binding domain STAT_int (PF02865, IPR013799, SM00964): STAT protein, protein interaction domain
164	STK26	interactor	4	0.667	0.400	DUF1241 (PF06840, IPR009652): Protein of unknown function (DUF1241) Pkinase (PF00069, IPR000719): Protein kinase domain
165	STRADB	interactor	3	1.000	0	Pkinase (PF00069, IPR000719): Protein kinase domain ASXH (PF13919, IPR028020): Asx homology domain
166	STUB1	suppressor	45	0.201	477.102	U-box (PF04564, IPR003613, SM00504): U-box domain ANAPC3 (PF12895): Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 (PF13414, IPR011990): TPR repeat TPR_20 (PF14561): Tetratricopeptide repeat
167	SYK	suppressor	19	0.288	71.090	Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain
168	TAB1	interactor	16	0.442	31.551	PP2C (PF00481, IPR001932): Protein phosphatase 2C
169	TAB2	oncoprotein	34	0.227	253.211	CUE (PF02845, IPR003892, SM00546): CUE domain DivIC (PF04977, IPR007060): Septum formation initiator Mnd1 (PF03962, IPR005647): Mnd1 family zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others
170	TAB3	oncoprotein	14	0.500	18.795	CUE (PF02845, IPR003892, SM00546): CUE domain Tmemb_cc2 (PF10267, IPR019394): Predicted transmembrane and coiled-coil 2 protein zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others
171	TANK	suppressor	19	0.340	55.419	DUF3713 (PF12506, IPR022186): Protein of unknown function (DUF3713) TBD (PF12845, IPR024581): TBD domain
172	TARS	interactor	2	1.000	0	HGTP_anticodon (PF03129, IPR004154): Anticodon binding domain TGS (PF02824, IPR004095): TGS domain tRNA-synt_2b (PF00587, IPR002314): tRNA synthetase class II core domain (G, H, P, S and T) tRNA_SAD (PF07973, IPR012947, SM00863): Threonyl and Alanyl tRNA synthetase second additional domain
173	TAX1BP1	interactor	8	0.571	4.704	CALCOCO1 (PF07888, IPR012852): Calcium binding and coiled-coil domain (CALCOCO1) like zf-Di19 (PF05605, IPR008598): Drought induced 19 protein (Di19), zinc-binding Myc-LZ (PF02344, IPR003327): Myc leucine zipper domain PolyA_pol (PF01743, IPR002646): Poly A polymerase head domain Spc24 (PF08286, IPR013252): Spc24 subunit of Ndc80 zf-C2H2_4 (PF13894): C2H2-type zinc finger PRKG1_interact (PF15898, IPR031775): cGMP-dependent protein kinase interacting domain
174	TDP2	interactor	9	0.361	13.682	Exo_endo_phos (PF03372, IPR005135): Endonuclease/Exonuclease/phosphatase family DUF4150 (PF13665, IPR025425): Domain of unknown function (DUF4150) UBA_4 (PF14555): UBA-like domain
175	TGFBR1	oncoprotein	15	0.267	40.844	Activin_recp (PF01064, IPR000472): Activin types I and II receptor domain Pkinase (PF00069, IPR000719): Protein kinase domain TGF_beta_GS (PF08515, IPR003605, SM00467): Transforming growth factor beta type I GS-motif
176	TGFBR2	suppressor	6	0.733	1.190	ecTbetaR2 (PF08917, IPR015013): Transforming growth factor beta receptor 2 ectodomain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
177	TICAM1	protein found in more fusions	17	0.300	55.982	Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator RHIM (PF12721, IPR025735): RIP homotypic interaction motif TIR_2 (PF13676, IPR000157): TIR domain
178	TICAM2	interactor	7	0.381	9.252	TIR_2 (PF13676, IPR000157): TIR domain
179	TIFA	interactor	5	0.500	1.476	FHA (PF00498, IPR000253, SM00240): FHA domain
180	TIRAP	interactor	14	0.397	26.232	TIR_2 (PF13676, IPR000157): TIR domain
181	TJP2	oncoprotein	1	0	0	PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) SH3_2 (PF07653, IPR011511): Variant SH3 domain Guanylate_kin (PF00625, IPR008145, SM00072): Guanylate kinase
182	TLR3	interactor	9	0.444	11.086	LRR_1 (PF00560, IPR001611): Leucine Rich Repeat LRRCT (PF01463, IPR000483, SM00082): Leucine rich repeat C-terminal domain LRRNT (PF01462, IPR000372, SM00013): Leucine rich repeat N-terminal domain TIR (PF01582, IPR000157, SM00255): TIR domain LRR_5 (PF13306, IPR026906): Leucine rich repeats (6 copies) LRR_8 (PF13855, IPR001611): Leucine rich repeat
183	TLR4	interactor	15	0.324	43.760	LRR_1 (PF00560, IPR001611): Leucine Rich Repeat TIR (PF01582, IPR000157, SM00255): TIR domain LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies) LRR_8 (PF13855, IPR001611): Leucine rich repeat LRR_9 (PF14580): Leucine-rich repeat
184	TLR9	interactor	8	0.571	4.555	LRR_1 (PF00560, IPR001611): Leucine Rich Repeat TIR (PF01582, IPR000157, SM00255): TIR domain LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies) LRR_6 (PF13516, IPR001611): Leucine Rich repeat LRR_8 (PF13855, IPR001611): Leucine rich repeat
185	TNFAIP3	suppressor	26	0.347	102.261	OTU (PF02338, IPR003323): OTU-like cysteine protease zf-A20 (PF01754, IPR002653, SM00259): A20-like zinc finger Thioredoxin_3 (PF13192, IPR012336): Thioredoxin domain
186	TNFRSF11A	oncoprotein	7	0.667	2.218	Abi (PF02517, IPR003675): CAAX protease self-immunity DAG1 (PF05454, IPR008465): Dystroglycan (Dystrophin-associated glycoprotein 1) KIX (PF02172, IPR003101): KIX domain TNFR_c6 (PF00020, IPR001368, SM00208): TNFR/NGFR cysteine-rich region
187	TNFRSF13B	oncoprotein	6	0.600	3.098	TACI-CRD2 (PF09305, IPR015384): TACI, cysteine-rich domain
188	TNFRSF17	oncoprotein	4	0.833	0.118	BCMA-Tall_bind (PF09257, IPR015337): BCMA, TALL-1 binding Adipogenin (PF15202, IPR027938): Adipogenin
189	TNFRSF1A	oncoprotein	26	0.367	98.224	Death (PF00531, IPR000488, SM00005): Death domain TNFR_c6 (PF00020, IPR001368, SM00208): TNFR/NGFR cysteine-rich region
190	TNFRSF1B	oncoprotein	10	0.639	5.802	TNFR_c6 (PF00020, IPR001368, SM00208): TNFR/NGFR cysteine-rich region
191	TOLLIP	interactor	17	0.258	55.375	C2 (PF00168, IPR000008, SM00239): C2 domain CUE (PF02845, IPR003892, SM00546): CUE domain
192	TOMM20	interactor	7	0.476	6.533	RSN1_7TM (PF02714, IPR003864): Calcium-dependent channel, 7TM region, putative phosphate MAS20 (PF02064, IPR002056): MAS20 protein import receptor
193	TOMM70	interactor	8	0.357	10.955	PBP_GOBP (PF01395, IPR006170, SM00708): PBP/GOBP family TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat TPR_8 (PF13181, IPR019734): Tetratricopeptide repeat TPR_12 (PF13424): Tetratricopeptide repeat TPR_14 (PF13428): Tetratricopeptide repeat TPR_17 (PF13431): Tetratricopeptide repeat TPR_19 (PF14559): Tetratricopeptide repeat NRBF2_MIT (PF17169): MIT domain of nuclear receptor-binding factor 2
194	TRADD	interactor	15	0.440	28.823	Death (PF00531, IPR000488, SM00005): Death domain TRADD_N (PF09034, IPR009095): TRADD, N-terminal domain TPR_14 (PF13428): Tetratricopeptide repeat
195	TRAF1	oncoprotein	35	0.273	206.100	HypA (PF01155, IPR000688): Hydrogenase/urease nickel incorporation, metallochaperone, hypA SlyX (PF04102, IPR007236): SlyX TRAF_BIRC3_bd (PF16673, IPR032070): TNF receptor-associated factor BIRC3 binding domain
196	TRAF2	interactor	71	0.148	1404.781	MATH (PF00917, IPR002083, SM00061): MATH domain Sina (PF03145, IPR018121): Seven in absentia protein family SlyX (PF04102, IPR007236): SlyX zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger) zf-TRAF (PF02176, IPR001293): TRAF-type zinc finger TRAF_BIRC3_bd (PF16673, IPR032070): TNF receptor-associated factor BIRC3 binding domain zf-C3HC4_5 (PF17121, IPR001841): Zinc finger, C3HC4 type (RING finger)
197	TRAF3IP1	interactor	3	1.000	0	MIP-T3 (PF10243): Microtubule-binding protein MIP-T3
198	TRAF3IP2	interactor	17	0.358	45.376	SEFIR (PF08357, IPR013568): SEFIR domain Trypan_PARP (PF05887, IPR008882): Procyclic acidic repetitive protein (PARP)
199	TRAF4	oncoprotein	23	0.234	97.643	MATH (PF00917, IPR002083, SM00061): MATH domain Sina (PF03145, IPR018121): Seven in absentia protein family zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger) zf-TRAF (PF02176, IPR001293): TRAF-type zinc finger
200	TRAF5	interactor	27	0.194	151.534	Sina (PF03145, IPR018121): Seven in absentia protein family zf-TRAF (PF02176, IPR001293): TRAF-type zinc finger zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger) zf-RING_4 (PF14570): RING/Ubox like zinc-binding domain HMMR_N (PF15905, IPR031787): Hyaluronan mediated motility receptor N-terminal Spc29 (PF17082, IPR031392): Spindle Pole Component 29
201	TRAFD1	interactor	3	0.667	0.333	zf-Di19 (PF05605, IPR008598): Drought induced 19 protein (Di19), zinc-binding DM (PF00751, IPR001275, SM00301): DM DNA binding domain zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-C2H2_4 (PF13894): C2H2-type zinc finger zf-C2HC_2 (PF13913): zinc-finger of a C2HC-type
202	TRAIP	interactor	15	0.330	31.151	Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein ORF6C (PF10552, IPR018878): ORF6C domain zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1
203	TRIM17	interactor	9	0.389	5.125	NlpE (PF04170, IPR007298): NlpE N-terminal domain SPRY (PF00622, IPR003877, SM00449): SPRY domain zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger PRY (PF13765, IPR006574, SM00589): SPRY-associated domain zf-Nse (PF11789, IPR004181): Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 (PF15227): zinc finger of C3HC4-type, RING
204	TRIM25	protein found in more fusions	14	0.295	29.070	Fes1 (PF08609, IPR013918): Nucleotide exchange factor Fes1 Pox_Rif (PF03340, IPR005008): Poxvirus rifampicin resistance protein SPRY (PF00622, IPR003877, SM00449): SPRY domain zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger PRY (PF13765, IPR006574, SM00589): SPRY-associated domain zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger Prok-RING_4 (PF14447): Prokaryotic RING finger family 4
205	TRIM37	oncoprotein	12	0.382	14.589	MATH (PF00917, IPR002083, SM00061): MATH domain zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger Kinetocho_Slk19 (PF12709, IPR024312): Central kinetochore-associated zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger) MRFAP1 (PF15155, IPR029254): MORF4 family-associated protein1 PRKG1_interact (PF15898, IPR031775): cGMP-dependent protein kinase interacting domain DUF5071 (PF16804, IPR031837): Domain of unknown function (DUF5071)
206	TRIM38	interactor	12	0.273	21.013	DUF342 (PF03961, IPR005646): Protein of unknown function (DUF342) SPRY (PF00622, IPR003877, SM00449): SPRY domain zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger PRY (PF13765, IPR006574, SM00589): SPRY-associated domain zf-C3HC4_4 (PF15227): zinc finger of C3HC4-type, RING
207	UBC	protein found in more fusions	86	0.113	2375.573	ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
208	UBE2D1	interactor	29	0.230	140.423	UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
209	UBE2D2	oncoprotein	29	0.259	128.877	UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
210	UBE2D3	interactor	23	0.216	69.004	UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
211	UBE2D4	interactor	11	0.222	10.282	UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
212	UBE2E1	protein found in more fusions	15	0.198	27.133	UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein
213	UBE2I	interactor	28	0.179	200.582	UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
214	UBE2L3	protein found in more fusions	17	0.417	29.855	UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
215	UBE2N	protein found in more fusions	20	0.363	48.896	UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
216	UBE2O	protein found in more fusions	9	0.536	3.991	BUD22 (PF09073, IPR015158): BUD22 UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme CCDC106 (PF15794, IPR031591): Coiled-coil domain-containing protein 106
217	UBE2V1	interactor	13	0.551	14.248	UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
218	UBOX5	interactor	12	0.309	14.838	U-box (PF04564, IPR003613, SM00504): U-box domain zf-RING_5 (PF14634, IPR001841): zinc-RING finger domain
219	UCHL1	suppressor	13	0.385	24.867	Peptidase_C12 (PF01088, IPR001578): Ubiquitin carboxyl-terminal hydrolase, family 1
220	UEVLD	interactor	3	1.000	0	Ldh_1_C (PF02866, IPR022383): lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N (PF00056, IPR001236): lactate/malate dehydrogenase, NAD binding domain UEV (PF05743, IPR008883): UEV domain
221	ULK1	protein found in more fusions	11	0.356	19.641	Pkinase (PF00069, IPR000719): Protein kinase domain DUF3543 (PF12063, IPR022708): Domain of unknown function (DUF3543) RCDG1 (PF15725, IPR031457): Renal cancer differentiation gene 1 protein
222	USP1	protein found in more fusions	5	0.833	0.500	UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase
223	USP10	protein found in more fusions	12	0.382	21.098	PAM2 (PF07145, IPR009818): Ataxin-2 C-terminal region UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase YukD (PF08817, IPR024962): WXG100 protein secretion system (Wss), protein YukD
224	USP15	oncoprotein	23	0.294	95.329	UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase DUSP (PF06337, IPR006615, SM00695): DUSP domain Ubiquitin_3 (PF14836, IPR028135): Ubiquitin-like domain
225	USP2	interactor	18	0.314	69.740	UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase
226	USP20	protein found in more fusions	8	0.524	6.800	UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase zf-UBP (PF02148, IPR001607, SM00290): Zn-finger in ubiquitin-hydrolases and other protein DUSP (PF06337, IPR006615, SM00695): DUSP domain
227	USP21	interactor	15	0.407	28.675	UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase
228	USP33	suppressor	8	0.571	8.133	UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase zf-UBP (PF02148, IPR001607, SM00290): Zn-finger in ubiquitin-hydrolases and other protein DUSP (PF06337, IPR006615, SM00695): DUSP domain
229	USP39	oncoprotein	5	0.600	1.682	UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase zf-UBP (PF02148, IPR001607, SM00290): Zn-finger in ubiquitin-hydrolases and other protein
230	USP4	oncoprotein	14	0.359	28.230	UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase DUSP (PF06337, IPR006615, SM00695): DUSP domain Ubiquitin_3 (PF14836, IPR028135): Ubiquitin-like domain
231	USP5	interactor	8	0.536	3.534	UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase zf-UBP (PF02148, IPR001607, SM00290): Zn-finger in ubiquitin-hydrolases and other protein
232	USP7	oncoprotein	21	0.300	78.530	MATH (PF00917, IPR002083, SM00061): MATH domain UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase USP7_ICP0_bdg (PF12436, IPR024729): ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 (PF14533, IPR029346): Ubiquitin-specific protease C-terminal
233	VARS	interactor	5	0.400	5.067	Anticodon_1 (PF08264, IPR013155): Anticodon-binding domain of tRNA GST_C (PF00043, IPR004046): Glutathione S-transferase, C-terminal domain tRNA-synt_1 (PF00133, IPR002300): tRNA synthetases class I (I, L, M and V) Val_tRNA-synt_C (PF10458, IPR019499): Valyl tRNA synthetase tRNA binding arm SUIM_assoc (PF16619): Unstructured region C-term to UIM in Ataxin3
234	VCP	protein found in more fusions	25	0.221	142.324	AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA) CDC48_2 (PF02933, IPR004201, SM01072): Cell division protein 48 (CDC48), domain 2 CDC48_N (PF02359, IPR003338, SM01073): Cell division protein 48 (CDC48), N-terminal domain TniB (PF05621, IPR008868): Bacterial TniB protein Vps4_C (PF09336, IPR015415): Vps4 C terminal oligomerisation domain DUF3944 (PF13099, IPR025217): Domain of unknown function (DUF3944)
235	VDAC1	interactor	7	0.381	9.317	Porin_3 (PF01459, IPR027246): Eukaryotic porin
236	VPS52	interactor	4	0.667	0.667	Vps52 (PF04129, IPR007258): Vps52 / Sac2 family COG5 (PF10392, IPR019465): Golgi transport complex subunit 5 Sec3_C (PF09763, IPR019160): Exocyst complex component Sec3
237	WDFY3	interactor	3	0.667	0.333	Beach (PF02138, IPR000409, SM01026): Beige/BEACH domain FYVE (PF01363, IPR000306, SM00064): FYVE zinc finger WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Laminin_G_3 (PF13385): Concanavalin A-like lectin/glucanases superfamily E3_UbLigase_R4 (PF13764, IPR025704): E3 ubiquitin-protein ligase UBR4 PH_BEACH (PF14844, IPR023362): PH domain associated with Beige/BEACH DUF4704 (PF15787, IPR031570): Domain of unknown function (DUF4704) DUF4800 (PF16057): Domain of unknown function (DUF4800)
238	WDR34	interactor	4	1.000	0	GTF2I (PF02946, IPR004212): GTF2I-like repeat WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
239	WDR5	interactor	9	0.333	12.336	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
240	WWP1	oncoprotein	10	0.556	4.439	C2 (PF00168, IPR000008, SM00239): C2 domain WW (PF00397, IPR001202, SM00456): WW domain HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
241	XIAP	interactor	34	0.231	240.540	BIR (PF00653, IPR001370, SM00238): Inhibitor of Apoptosis domain zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
242	YBX1	oncoprotein	12	0.288	27.083	CSD (PF00313, IPR002059): 'Cold-shock' DNA-binding domain PBP1_TM (PF14812, IPR032730): Transmembrane domain of transglycosylase PBP1 at N-terminal FXR_C1 (PF16096, IPR032172): Fragile X-related 1 protein C-terminal region 2
243	YES1	oncoprotein	7	0.333	9.100	Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain YdjC (PF04794, IPR006879): YdjC-like protein SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
244	ZC3H12A	interactor	8	0.524	5.987	RNase_Zc3h12a (PF11977, IPR021869): Zc3h12a-like Ribonuclease NYN domain zf-CCCH_2 (PF14608): RNA-binding, Nab2-type zinc finger
245	ZFAND5	interactor	5	0.700	0.512	zf-A20 (PF01754, IPR002653, SM00259): A20-like zinc finger zf-AN1 (PF01428, IPR000058, SM00154): AN1-like Zinc finger FAM53 (PF15242, IPR029356): Family of FAM53
246	ZMYND11	suppressor	10	0.472	10.770	DUF1002 (PF06207, IPR009343): Protein of unknown function (DUF1002) DUF1353 (PF07087, IPR010767): Protein of unknown function (DUF1353) PWWP (PF00855, IPR000313, SM00293): PWWP domain zf-MYND (PF01753, IPR002893): MYND finger zf-UBR (PF02207, IPR003126): Putative zinc finger in N-recognin (UBR box) Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
247	ZNF675	interactor	1	0	0	KRAB (PF01352, IPR001909, SM00349): KRAB box zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
248	ZRANB1	interactor	2	1.000	0	Copper-fist (PF00649, IPR001083, SM01090): Copper fist DNA binding domain OTU (PF02338, IPR003323): OTU-like cysteine protease zf-Sec23_Sec24 (PF04810, IPR006895): Sec23/Sec24 zinc finger zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others

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