1 |
TRAF6 | parental protein | 248 | 0.046 | 42317.913 | SlyX (PF04102, IPR007236): SlyX zf-TRAF (PF02176, IPR001293): TRAF-type zinc finger zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger) |
2 |
AJUBA | oncoprotein | 3 | 1.000 | 0 | LIM (PF00412, IPR001781, SM00132): LIM domain |
3 |
AKT1 | oncoprotein | 35 | 0.225 | 256.507 | PH (PF00169, IPR001849, SM00233): PH domain Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain |
4 |
AMBRA1 | interactor | 16 | 0.442 | 42.387 | Acyl_CoA_thio (PF02551, IPR025652): Acyl-CoA thioesterase eIF2A (PF08662, IPR013979): Eukaryotic translation initiation factor eIF2A WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Spt20 (PF12090, IPR021950): Spt20 family ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain |
5 |
APP | protein found in more fusions | 54 | 0.076 | 1056.961 | APP_N (PF02177, IPR015849, SM00006): Amyloid A4 N-terminal heparin-binding Beta-APP (PF03494, IPR013803): Beta-amyloid peptide (beta-APP) BUD22 (PF09073, IPR015158): BUD22 IncA (PF04156, IPR007285): IncA protein Kunitz_BPTI (PF00014, IPR002223, SM00131): Kunitz/Bovine pancreatic trypsin inhibitor domain APP_amyloid (PF10515, IPR019543): beta-amyloid precursor protein C-terminus APP_Cu_bd (PF12924, IPR011178): Copper-binding of amyloid precursor, CuBD APP_E2 (PF12925, IPR024329): E2 domain of amyloid precursor protein |
6 |
APPL1 | interactor | 11 | 0.333 | 19.763 | ATP-synt_E (PF05680, IPR008386): ATP synthase E chain Fzo_mitofusin (PF04799, IPR006884): fzo-like conserved region PH (PF00169, IPR001849, SM00233): PH domain PID (PF00640, IPR006020, SM00462): Phosphotyrosine interaction domain (PTB/PID) BAR_3 (PF16746): BAR domain of APPL family |
7 |
ARRB1 | interactor | 13 | 0.436 | 22.901 | Arrestin_C (PF02752, IPR011022, SM01017): Arrestin (or S-antigen), C-terminal domain Arrestin_N (PF00339, IPR011021): Arrestin (or S-antigen), N-terminal domain |
8 |
ARRB2 | interactor | 18 | 0.346 | 55.540 | Arrestin_C (PF02752, IPR011022, SM01017): Arrestin (or S-antigen), C-terminal domain Arrestin_N (PF00339, IPR011021): Arrestin (or S-antigen), N-terminal domain |
9 |
ASXL2 | interactor | 3 | 0.667 | 0.095 | DUF1180 (PF06679, IPR009565): Protein of unknown function (DUF1180) K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain HARE-HTH (PF05066, IPR007759): HB1, ASXL, restriction endonuclease HTH domain ASXH (PF13919, IPR028020): Asx homology domain PHD_3 (PF13922, IPR026905): PHD domain of transcriptional enhancer, Asx DUF4551 (PF15087, IPR027878): Protein of unknown function (DUF4551) |
10 |
ATM | suppressor | 8 | 0.476 | 5.983 | FAT (PF02259, IPR003151): FAT domain FATC (PF02260, IPR003152): FATC domain HEAT (PF02985, IPR000357): HEAT repeat PI3_PI4_kinase (PF00454, IPR000403, SM00146): Phosphatidylinositol 3- and 4-kinase TAN (PF11640, IPR021668): Telomere-length maintenance and DNA damage repair ANAPC5 (PF12862, IPR026000): Anaphase-promoting complex subunit 5 |
11 |
ATXN3 | interactor | 12 | 0.455 | 15.656 | Josephin (PF02099, IPR006155): Josephin UIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif SUIM_assoc (PF16619): Unstructured region C-term to UIM in Ataxin3 |
12 |
BCL10 | suppressor | 19 | 0.477 | 28.153 | CARD (PF00619, IPR001315, SM00114): Caspase recruitment domain |
13 |
BECN1 | suppressor | 13 | 0.318 | 30.817 | APG6 (PF04111, IPR007243): Autophagy protein Apg6 Ima1_N (PF09779, IPR018617): Ima1 N-terminal domain BH3 (PF15285, IPR029318): Beclin-1 BH3 domain, Bcl-2-interacting |
14 |
BIRC2 | oncoprotein | 28 | 0.385 | 82.049 | BIR (PF00653, IPR001370, SM00238): Inhibitor of Apoptosis domain CARD (PF00619, IPR001315, SM00114): Caspase recruitment domain zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger) |
15 |
BIRC3 | oncoprotein | 31 | 0.372 | 113.632 | BIR (PF00653, IPR001370, SM00238): Inhibitor of Apoptosis domain CARD (PF00619, IPR001315, SM00114): Caspase recruitment domain zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger) |
16 |
BMPR1B | interactor | 7 | 0.533 | 2.037 | Activin_recp (PF01064, IPR000472): Activin types I and II receptor domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase TGF_beta_GS (PF08515, IPR003605, SM00467): Transforming growth factor beta type I GS-motif |
17 |
CALCOCO2 | interactor | 13 | 0.394 | 25.008 | bZIP_1 (PF00170, IPR004827): bZIP transcription factor CALCOCO1 (PF07888, IPR012852): Calcium binding and coiled-coil domain (CALCOCO1) like DUF641 (PF04859, IPR006943): Plant protein of unknown function (DUF641) OmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like) Jnk-SapK_ap_N (PF09744, IPR019143): JNK_SAPK-associated protein-1 GAS (PF13851, IPR025593): Growth-arrest specific micro-tubule binding zf-C2H2_4 (PF13894): C2H2-type zinc finger |
18 |
CANX | interactor | 6 | 0.600 | 3.567 | Calreticulin (PF00262, IPR001580): Calreticulin family DUF1510 (PF07423, IPR009988): Protein of unknown function (DUF1510) TRAP_alpha (PF03896, IPR005595): Translocon-associated protein (TRAP), alpha subunit |
19 |
CARD11 | oncoprotein | 12 | 0.527 | 10.324 | CARD (PF00619, IPR001315, SM00114): Caspase recruitment domain DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664) Cnn_1N (PF07989, IPR012943): Centrosomin N-terminal motif 1 PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) zf-C4H2 (PF10146, IPR018482): Zinc finger-containing protein Guanylate_kin (PF00625, IPR008145, SM00072): Guanylate kinase DUF3450 (PF11932, IPR016866): Protein of unknown function (DUF3450) |
20 |
CASP4 | interactor | 4 | 0.667 | 0.889 | CARD (PF00619, IPR001315, SM00114): Caspase recruitment domain Peptidase_C14 (PF00656, IPR011600): Caspase domain |
21 |
CASP8 | suppressor | 21 | 0.395 | 60.483 | DED (PF01335, IPR001875, SM00031): Death effector domain Peptidase_C14 (PF00656, IPR011600): Caspase domain |
22 |
CBLB | oncoprotein | 12 | 0.309 | 21.932 | Cbl_N (PF02262, IPR003153): CBL proto-oncogene N-terminal domain 1 Cbl_N2 (PF02761, IPR014741): CBL proto-oncogene N-terminus, EF hand-like domain Cbl_N3 (PF02762, IPR014742): CBL proto-oncogene N-terminus, SH2-like domain UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain Prok-RING_4 (PF14447): Prokaryotic RING finger family 4 PRIMA1 (PF16101): Proline-rich membrane anchor 1 |
23 |
CD40 | protein found in more fusions | 17 | 0.392 | 35.705 | Glycophorin_A (PF01102, IPR001195): Glycophorin A TNFR_c6 (PF00020, IPR001368, SM00208): TNFR/NGFR cysteine-rich region |
24 |
CHUK | suppressor | 38 | 0.275 | 229.495 | Pkinase (PF00069, IPR000719): Protein kinase domain IKKbetaNEMObind (PF12179, IPR022007): I-kappa-kinase-beta NEMO binding domain |
25 |
CSNK1G1 | interactor | 2 | 1.000 | 0 | Pkinase (PF00069, IPR000719): Protein kinase domain CK1gamma_C (PF12605, IPR022247): Casein kinase 1 gamma C terminal |
26 |
CTPS1 | interactor | 5 | 0.667 | 0.750 | CTP_synth_N (PF06418, IPR017456): CTP synthase N-terminus GATase (PF00117, IPR017926): Glutamine amidotransferase class-I |
27 |
CYCS | interactor | 2 | 1.000 | 0 | Cytochrom_C (PF00034, IPR003088): Cytochrome c |
28 |
CYLD | suppressor | 13 | 0.436 | 19.236 | CAP_GLY (PF01302, IPR000938, SM01052): CAP-Gly domain UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase zf-HIT (PF04438, IPR007529): HIT zinc finger CYLD_phos_site (PF16607): Phosphorylation region of CYLD, unstructured |
29 |
DCBLD2 | interactor | 1 | 0 | 0 | CUB (PF00431, IPR000859, SM00042): CUB domain LCCL (PF03815, IPR004043, SM00603): LCCL domain Syndecan (PF01034, IPR027789): Syndecan domain F5_F8_type_C (PF00754, IPR000421, SM00231): F5/8 type C domain |
30 |
DDB1 | protein found in more fusions | 12 | 0.436 | 21.208 | CPSF_A (PF03178, IPR004871): CPSF A subunit region MMS1_N (PF10433): Mono-functional DNA-alkylating methyl methanesulfonate N-term |
31 |
DDX3X | suppressor | 7 | 0.381 | 6.515 | DEAD (PF00270, IPR011545): DEAD/DEAH box helicase DUF755 (PF05501, IPR008474): Domain of unknown function (DUF755) Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain |
32 |
DEUP1 | suppressor | 3 | 1.000 | 0 | APG6 (PF04111, IPR007243): Autophagy protein Apg6 TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein bZIP_2 (PF07716, IPR004827, SM00338): Basic region leucine zipper Lebercilin (PF15619, IPR028933): Ciliary protein causing Leber congenital amaurosis disease CEP63 (PF17045, IPR031470): Centrosomal protein of 63 kDa |
33 |
EDA2R | suppressor | 4 | 0.667 | 1.667 | Ephrin_rec_like (PF07699, IPR011641): Putative ephrin-receptor like TNFR_c6 (PF00020, IPR001368, SM00208): TNFR/NGFR cysteine-rich region |
34 |
EDARADD | interactor | 7 | 0.600 | 2.583 | Death (PF00531, IPR000488, SM00005): Death domain SCO1-SenC (PF02630, IPR003782): SCO1/SenC |
35 |
EIF2AK2 | oncoprotein | 13 | 0.439 | 17.123 | dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif Pkinase (PF00069, IPR000719): Protein kinase domain |
36 |
EIF4E2 | interactor | 4 | 0.500 | 1.619 | IF4E (PF01652, IPR001040): Eukaryotic initiation factor 4E |
37 |
EPPK1 | interactor | 4 | 0.833 | 0.333 | DUF1840 (PF08895, IPR014991): Domain of unknown function (DUF1840) HupF_HypC (PF01455, IPR001109): HupF/HypC family Plectin (PF00681, IPR001101, SM00250): Plectin repeat RPA_interact_N (PF14766, IPR028158): Replication protein A interacting N-terminal |
38 |
ERN1 | interactor | 8 | 0.476 | 4.882 | Pkinase (PF00069, IPR000719): Protein kinase domain PQQ (PF01011, IPR002372, SM00564): PQQ enzyme repeat Ribonuc_2-5A (PF06479, IPR010513): Ribonuclease 2-5A CytochromB561_N (PF09786, IPR019176): Cytochrome B561, N terminal PQQ_2 (PF13360, IPR002372): PQQ-like domain |
39 |
ESR1 | suppressor | 31 | 0.182 | 237.673 | Oest_recep (PF02159, IPR001292): Oestrogen receptor zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor ESR1_C (PF12743, IPR024736): Oestrogen-type nuclear receptor final C-terminal |
40 |
FHL2 | oncoprotein | 11 | 0.333 | 19.871 | LIM (PF00412, IPR001781, SM00132): LIM domain zf-ribbon_3 (PF13248): zinc-ribbon domain |
41 |
FOXG1 | oncoprotein | 2 | 1.000 | 0 | SelP_N (PF04592, IPR007671): Selenoprotein P, N terminal region SPX (PF03105, IPR004331): SPX domain DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360) Forkhead (PF00250, IPR001766, SM00339): Forkhead domain |
42 |
FYN | oncoprotein | 16 | 0.305 | 49.344 | Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain |
43 |
GANAB | suppressor | 3 | 1.000 | 0 | Glyco_hydro_31 (PF01055, IPR000322): Glycosyl hydrolases family 31 Gal_mutarotas_2 (PF13802, IPR025887): Galactose mutarotase-like DUF5110 (PF17137): Domain of unknown function (DUF5110) |
44 |
GTF2I | interactor | 10 | 0.289 | 21.167 | GTF2I (PF02946, IPR004212): GTF2I-like repeat |
45 |
HIF1A | suppressor | 19 | 0.234 | 82.706 | Dicty_REP (PF05086, IPR007778): Dictyostelium (Slime Mold) REP protein HIF-1a_CTAD (PF08778, IPR014887): HIF-1 alpha C terminal transactivation domain HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain PAS (PF00989, IPR013767, SM00091): PAS fold PAS_3 (PF08447, IPR013655): PAS fold HIF-1 (PF11413, IPR021537): Hypoxia-inducible factor-1 |
46 |
HSD17B10 | interactor | 8 | 0.321 | 9.318 | adh_short (PF00106, IPR002198): short chain dehydrogenase |
47 |
HSPA4 | interactor | 32 | 0.228 | 227.250 | Herpes_ICP4_N (PF03584, IPR005206): Herpesvirus ICP4-like protein N-terminal region HSP70 (PF00012, IPR013126): Hsp70 protein TP53IP5 (PF15331, IPR029290): Cellular tumour antigen p53-inducible 5 |
48 |
HSPB2 | interactor | 6 | 0.400 | 2.633 | Crystallin (PF00525, IPR003090): Alpha crystallin A chain, N terminal HSP20 (PF00011, IPR002068): Hsp20/alpha crystallin family |
49 |
HTT | protein found in more fusions | 10 | 0.389 | 10.976 | HEAT (PF02985, IPR000357): HEAT repeat SPX (PF03105, IPR004331): SPX domain TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit DUF3652 (PF12372, IPR024613): Huntingtin protein region Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region HEAT_EZ (PF13513): HEAT-like repeat HEAT_2 (PF13646): HEAT repeats |
50 |
IARS | interactor | 7 | 0.524 | 5.646 | Anticodon_1 (PF08264, IPR013155): Anticodon-binding domain of tRNA tRNA-synt_1 (PF00133, IPR002300): tRNA synthetases class I (I, L, M and V) |
51 |
IFIT3 | interactor | 9 | 0.357 | 13.982 | TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat TPR_10 (PF13374, IPR011990): Tetratricopeptide repeat TPR_12 (PF13424): Tetratricopeptide repeat TPR_17 (PF13431): Tetratricopeptide repeat TPR_19 (PF14559): Tetratricopeptide repeat |
52 |
IKBKB | protein found in more fusions | 33 | 0.284 | 191.506 | FliT (PF05400, IPR008622): Flagellar protein FliT Glyco_hydro_65m (PF03632, IPR005195): Glycosyl hydrolase family 65 central catalytic domain Pkinase (PF00069, IPR000719): Protein kinase domain SlyX (PF04102, IPR007236): SlyX ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family IKKbetaNEMObind (PF12179, IPR022007): I-kappa-kinase-beta NEMO binding domain |
53 |
IKBKG | interactor | 53 | 0.201 | 652.655 | CENP-H (PF05837, IPR008426): Centromere protein H (CENP-H) DUF725 (PF05267, IPR007931): Protein of unknown function (DUF725) NEMO (PF11577, IPR021063): NF-kappa-B essential modulator NEMO LLC1 (PF14945, IPR020339): Normal lung function maintenance, Low in Lung Cancer 1 protein CC2-LZ (PF16516, IPR032419): Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator |
54 |
IL17A | suppressor | 4 | 1.000 | 0 | IL17 (PF06083, IPR010345): Interleukin-17 |
55 |
IL17RA | interactor | 5 | 0.800 | 1.333 | SEFIR (PF08357, IPR013568): SEFIR domain IL17R_fnIII_D1 (PF16556, IPR032356): Interleukin-17 receptor, fibronectin-III-like domain 1 IL17R_fnIII_D2 (PF16578): Interleukin 17 receptor D |
56 |
IL1R1 | interactor | 9 | 0.583 | 8.017 | TIR (PF01582, IPR000157, SM00255): TIR domain Ig_2 (PF13895, IPR007110): Immunoglobulin domain Ig_3 (PF13927): Immunoglobulin domain |
57 |
IL1RL1 | interactor | 5 | 0.700 | 1.100 | I-set (PF07679, IPR013098): Immunoglobulin I-set domain TIR (PF01582, IPR000157, SM00255): TIR domain Ig_2 (PF13895, IPR007110): Immunoglobulin domain Ig_3 (PF13927): Immunoglobulin domain |
58 |
IRAK1 | interactor | 39 | 0.203 | 372.595 | Death (PF00531, IPR000488, SM00005): Death domain Pkinase (PF00069, IPR000719): Protein kinase domain |
59 |
IRAK2 | oncoprotein | 16 | 0.350 | 48.736 | Death (PF00531, IPR000488, SM00005): Death domain Pkinase (PF00069, IPR000719): Protein kinase domain |
60 |
IRAK3 | interactor | 5 | 1.000 | 0 | Death (PF00531, IPR000488, SM00005): Death domain Pkinase (PF00069, IPR000719): Protein kinase domain |
61 |
IRAK4 | interactor | 14 | 0.462 | 22.688 | Death (PF00531, IPR000488, SM00005): Death domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase |
62 |
IRF3 | suppressor | 13 | 0.348 | 26.749 | IRF (PF00605, IPR001346, SM00348): Interferon regulatory factor transcription factor IRF-3 (PF10401, IPR019471): Interferon-regulatory factor 3 |
63 |
IRF4 | suppressor | 5 | 0.600 | 1.115 | IRF (PF00605, IPR001346, SM00348): Interferon regulatory factor transcription factor IRF-3 (PF10401, IPR019471): Interferon-regulatory factor 3 |
64 |
IRF5 | suppressor | 7 | 0.467 | 2.910 | IRF (PF00605, IPR001346, SM00348): Interferon regulatory factor transcription factor IRF-3 (PF10401, IPR019471): Interferon-regulatory factor 3 |
65 |
IRF7 | interactor | 8 | 0.476 | 4.278 | IRF (PF00605, IPR001346, SM00348): Interferon regulatory factor transcription factor IRF-3 (PF10401, IPR019471): Interferon-regulatory factor 3 |
66 |
IRF8 | suppressor | 3 | 1.000 | 0 | IRF (PF00605, IPR001346, SM00348): Interferon regulatory factor transcription factor IRF-3 (PF10401, IPR019471): Interferon-regulatory factor 3 |
67 |
ITCH | interactor | 24 | 0.213 | 111.396 | C2 (PF00168, IPR000008, SM00239): C2 domain WW (PF00397, IPR001202, SM00456): WW domain HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase) |
68 |
JAK2 | oncoprotein | 11 | 0.444 | 15.221 | FERM_M (PF00373, IPR019748): FERM central domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain |
69 |
KCNQ1 | interactor | 3 | 0.667 | 0.500 | Ion_trans (PF00520, IPR005821): Ion transport protein KCNQ_channel (PF03520, IPR013821): KCNQ voltage-gated potassium channel Sensor (PF13796, IPR025828): Putative sensor |
70 |
KIR2DL4 | interactor | 1 | 0 | 0 | ig (PF00047, IPR013151, SM00409): Immunoglobulin domain SVM_signal (PF12113, IPR021970): SVM protein signal sequence |
71 |
KMT2E | interactor | 5 | 0.400 | 3.567 | CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal PHD (PF00628, IPR019787, SM00249): PHD-finger SET (PF00856, IPR001214, SM00317): SET domain MSA-2c (PF12238, IPR021060): Merozoite surface antigen 2c DUF4124 (PF13511, IPR025392): Domain of unknown function (DUF4124) PHD_3 (PF13922, IPR026905): PHD domain of transcriptional enhancer, Asx DUF4666 (PF15697, IPR031421): Domain of unknown function (DUF4666) PRIMA1 (PF16101): Proline-rich membrane anchor 1 |
72 |
KRAS | oncoprotein | 13 | 0.242 | 38.008 | Ras (PF00071, IPR001806, SM00173): Ras family |
73 |
LAT | interactor | 3 | 1.000 | 0 | LAT (PF15234, IPR008359): Linker for activation of T-cells |
74 |
LGMN | interactor | 1 | 0 | 0 | Peptidase_C13 (PF01650, IPR001096): Peptidase C13 family |
75 |
LIMD1 | suppressor | 4 | 0.667 | 0.250 | LIM (PF00412, IPR001781, SM00132): LIM domain |
76 |
MAGEE2 | interactor | 2 | 1.000 | 0 | MAGE (PF01454, IPR002190): MAGE family |
77 |
MALT1 | oncoprotein | 14 | 0.590 | 8.538 | Peptidase_C14 (PF00656, IPR011600): Caspase domain V-set (PF07686, IPR013106): Immunoglobulin V-set domain Ig_2 (PF13895, IPR007110): Immunoglobulin domain Ig_3 (PF13927): Immunoglobulin domain |
78 |
MAP2K6 | interactor | 5 | 0.700 | 1.833 | Pkinase (PF00069, IPR000719): Protein kinase domain |
79 |
MAP3K11 | interactor | 9 | 0.714 | 1.841 | APG6 (PF04111, IPR007243): Autophagy protein Apg6 Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH3_9 (PF14604, IPR001452): Variant SH3 domain |
80 |
MAP3K14 | interactor | 16 | 0.514 | 18.462 | Pkinase (PF00069, IPR000719): Protein kinase domain |
81 |
MAP3K3 | oncoprotein | 12 | 0.400 | 12.169 | PB1 (PF00564, IPR000270, SM00666): PB1 domain Pkinase (PF00069, IPR000719): Protein kinase domain |
82 |
MAP3K5 | oncoprotein | 22 | 0.271 | 91.155 | Pkinase (PF00069, IPR000719): Protein kinase domain DUF4071 (PF13281, IPR025136): Domain of unknown function (DUF4071) |
83 |
MAP3K7 | oncoprotein | 51 | 0.182 | 642.088 | Mnd1 (PF03962, IPR005647): Mnd1 family Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase |
84 |
MAP3K8 | suppressor | 7 | 0.667 | 1.700 | Pkinase (PF00069, IPR000719): Protein kinase domain IML1 (PF12257, IPR027244): Vacuolar membrane-associated protein Iml1 |
85 |
MAPT | protein found in more fusions | 15 | 0.484 | 22.408 | Tubulin-binding (PF00418, IPR001084): Tau and MAP protein, tubulin-binding repeat |
86 |
MARCH5 | interactor | 10 | 0.306 | 7.573 | DUF2517 (PF10725, IPR019663): Protein of unknown function (DUF2517) RINGv (PF12906, IPR011016, SM00744): RING-variant domain |
87 |
MAST2 | oncoprotein | 3 | 0.667 | 0.182 | DUF1908 (PF08926, IPR015022): Domain of unknown function (DUF1908) PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) Pkinase (PF00069, IPR000719): Protein kinase domain |
88 |
MAVS | interactor | 28 | 0.225 | 166.949 | Ice_nucleation (PF00818, IPR000258): Ice nucleation protein repeat CARD_2 (PF16739, IPR031964): Caspase recruitment domain |
89 |
MCL1 | oncoprotein | 6 | 0.500 | 3.233 | Bcl-2 (PF00452, IPR026298): Apoptosis regulator proteins, Bcl-2 family |
90 |
MCM7 | protein found in more fusions | 8 | 0.381 | 4.714 | MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family MCM_N (PF14551, IPR027925): MCM N-terminal domain MCM_OB (PF17207): MCM OB domain |
91 |
MEOX2 | interactor | 4 | 0.500 | 3.000 | Homeobox (PF00046, IPR001356, SM00389): Homeobox domain |
92 |
MSR1 | interactor | 1 | 0 | 0 | bZIP_1 (PF00170, IPR004827): bZIP transcription factor Collagen (PF01391, IPR008160): Collagen triple helix repeat (20 copies) Macscav_rec (PF03523, IPR003543): Macrophage scavenger receptor Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein SRCR (PF00530, IPR001190): Scavenger receptor cysteine-rich domain AATF-Che1 (PF13339, IPR025160): Apoptosis antagonizing transcription factor |
93 |
MTHFD1 | interactor | 4 | 0.667 | 0.297 | FTHFS (PF01268, IPR000559): Formate--tetrahydrofolate ligase THF_DHG_CYH (PF00763, IPR020630): Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C (PF02882, IPR020631): Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain |
94 |
MTOR | oncoprotein | 18 | 0.382 | 40.572 | DUF1104 (PF06518, IPR009488): Protein of unknown function (DUF1104) EPSP_synthase (PF00275, IPR001986): EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) FAT (PF02259, IPR003151): FAT domain FATC (PF02260, IPR003152): FATC domain HEAT (PF02985, IPR000357): HEAT repeat FRB_dom (PF08771, IPR009076): FKBP12-rapamycin binding domain V-ATPase_H_N (PF03224, IPR004908): V-ATPase subunit H PI3_PI4_kinase (PF00454, IPR000403, SM00146): Phosphatidylinositol 3- and 4-kinase DUF3385 (PF11865, IPR024585): Domain of unknown function (DUF3385) HEAT_EZ (PF13513): HEAT-like repeat HEAT_2 (PF13646): HEAT repeats TPR_19 (PF14559): Tetratricopeptide repeat |
95 |
MUS81 | suppressor | 3 | 0.667 | 0.333 | ERCC4 (PF02732, IPR006166, SM00891): ERCC4 domain MutL (PF13941, IPR006230): MutL protein HHH_8 (PF14716, IPR010996): Helix-hairpin-helix domain |
96 |
MYB | oncoprotein | 5 | 0.500 | 3.500 | Cmyb_C (PF09316, IPR015395): C-myb, C-terminal LMSTEN (PF07988, IPR012642): LMSTEN motif Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain |
97 |
MYD88 | oncoprotein | 27 | 0.218 | 170.873 | Death (PF00531, IPR000488, SM00005): Death domain TIR (PF01582, IPR000157, SM00255): TIR domain |
98 |
NASP | interactor | 4 | 1.000 | 0 | Vfa1 (PF08432, IPR013640): AAA-ATPase Vps4-associated protein 1 DUF913 (PF06025, IPR010314): Domain of Unknown Function (DUF913) SlyX (PF04102, IPR007236): SlyX TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat TraV (PF09676, IPR014118): Type IV conjugative transfer system lipoprotein (TraV) SHNi-TPR (PF10516, IPR019544): SHNi-TPR XhlA (PF10779, IPR019715): Haemolysin XhlA TPR_8 (PF13181, IPR019734): Tetratricopeptide repeat CCSAP (PF15748, IPR029774): Centriole, cilia and spindle-associated MAP17 (PF15807, IPR031627): Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 |
99 |
NFATC2IP | interactor | 5 | 0.600 | 1.951 | Rad60-SLD (PF11976, IPR022617): Ubiquitin-2 like Rad60 SUMO-like FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 |
100 |
NGFR | suppressor | 11 | 0.489 | 8.776 | LHC (PF00556, IPR000066): Antenna complex alpha/beta subunit |
101 |
NLRC3 | interactor | 1 | 0 | 0 | NACHT (PF05729): NACHT domain LRR_6 (PF13516, IPR001611): Leucine Rich repeat LRR_8 (PF13855, IPR001611): Leucine rich repeat |
102 |
NLRX1 | interactor | 4 | 0.667 | 0.900 | NACHT (PF05729): NACHT domain LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies) AAA_16 (PF13191): AAA ATPase domain AAA_22 (PF13401, IPR003593): AAA domain LRR_6 (PF13516, IPR001611): Leucine Rich repeat |
103 |
NOD2 | interactor | 14 | 0.590 | 8.426 | CARD (PF00619, IPR001315, SM00114): Caspase recruitment domain NACHT (PF05729): NACHT domain LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies) LRR_6 (PF13516, IPR001611): Leucine Rich repeat |
104 |
NR0B2 | suppressor | 2 | 1.000 | 0 | Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor |
105 |
NR2C2 | suppressor | 10 | 0.361 | 15.486 | Flagellin_N (PF00669, IPR001029): Bacterial flagellin N-terminal helical region zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor |
106 |
NTRK1 | oncoprotein | 55 | 0.101 | 1017.907 | I-set (PF07679, IPR013098): Immunoglobulin I-set domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase LRR_8 (PF13855, IPR001611): Leucine rich repeat TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain |
107 |
NTRK2 | oncoprotein | 4 | 0.500 | 1.900 | I-set (PF07679, IPR013098): Immunoglobulin I-set domain LRRNT (PF01462, IPR000372, SM00013): Leucine rich repeat N-terminal domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase LRR_8 (PF13855, IPR001611): Leucine rich repeat TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain |
108 |
NUMBL | interactor | 3 | 0.667 | 0.333 | DUF1932 (PF09130, IPR015814): Domain of unknown function (DUF1932) NumbF (PF06311, IPR010449): NUMB domain PID (PF00640, IPR006020, SM00462): Phosphotyrosine interaction domain (PTB/PID) DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360) DUF2722 (PF10846, IPR021216): Protein of unknown function (DUF2722) SUIM_assoc (PF16619): Unstructured region C-term to UIM in Ataxin3 |
109 |
OTUB1 | interactor | 26 | 0.231 | 147.369 | Peptidase_C65 (PF10275, IPR019400): Peptidase C65 Otubain |
110 |
OTUB2 | interactor | 10 | 0.444 | 13.560 | Peptidase_C65 (PF10275, IPR019400): Peptidase C65 Otubain |
111 |
OTUD7A | interactor | 2 | 1.000 | 0 | OTU (PF02338, IPR003323): OTU-like cysteine protease Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein zf-A20 (PF01754, IPR002653, SM00259): A20-like zinc finger UBA_4 (PF14555): UBA-like domain CCDC106 (PF15794, IPR031591): Coiled-coil domain-containing protein 106 AP3D1 (PF06375): AP-3 complex subunit delta-1 |
112 |
OTUD7B | interactor | 4 | 0.500 | 0.956 | OTU (PF02338, IPR003323): OTU-like cysteine protease zf-A20 (PF01754, IPR002653, SM00259): A20-like zinc finger UBA_4 (PF14555): UBA-like domain CCDC106 (PF15794, IPR031591): Coiled-coil domain-containing protein 106 |
113 |
PAICS | interactor | 5 | 0.667 | 0.682 | AIRC (PF00731, IPR000031, SM01001): AIR carboxylase SAICAR_synt (PF01259, IPR028923): SAICAR synthetase |
114 |
PARK7 | suppressor | 11 | 0.378 | 15.644 | DJ-1_PfpI (PF01965, IPR002818): DJ-1/PfpI family |
115 |
PDLIM7 | interactor | 10 | 0.400 | 18.719 | LIM (PF00412, IPR001781, SM00132): LIM domain PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) zinc_ribbon_10 (PF10058, IPR019273): Predicted integral membrane zinc-ribbon metal-binding protein DUF4749 (PF15936, IPR031847): Domain of unknown function (DUF4749) |
116 |
PEBP1 | suppressor | 2 | 1.000 | 0 | PBP (PF01161, IPR008914): Phosphatidylethanolamine-binding protein |
117 |
PELI1 | interactor | 14 | 0.352 | 35.540 | Pellino (PF04710, IPR006800): Pellino |
118 |
PELI2 | interactor | 5 | 0.700 | 1.833 | Pellino (PF04710, IPR006800): Pellino |
119 |
PELI3 | interactor | 11 | 0.400 | 15.349 | Pellino (PF04710, IPR006800): Pellino |
120 |
PFAS | interactor | 5 | 0.600 | 1.700 | AIRS_C (PF02769, IPR010918): AIR synthase related protein, C-terminal domain GATase_5 (PF13507): CobB/CobQ-like glutamine amidotransferase domain |
121 |
PINK1 | protein found in more fusions | 18 | 0.272 | 62.974 | Pkinase (PF00069, IPR000719): Protein kinase domain |
122 |
PLEKHF2 | interactor | 3 | 0.667 | 0.667 | FYVE (PF01363, IPR000306, SM00064): FYVE zinc finger PH (PF00169, IPR001849, SM00233): PH domain |
123 |
PLEKHO1 | suppressor | 5 | 0.500 | 1.008 | PH (PF00169, IPR001849, SM00233): PH domain DUF3055 (PF11256, IPR021415): Protein of unknown function (DUF3055) |
124 |
POLI | interactor | 4 | 0.667 | 1.095 | IMS (PF00817, IPR001126): impB/mucB/samB family Cdd1 (PF11731, IPR021725): Pathogenicity locus IMS_HHH (PF11798, IPR024728): IMS family HHH motif IMS_C (PF11799, IPR017961): impB/mucB/samB family C-terminal domain DUF4414 (PF14377, IPR025527): Domain of unknown function (DUF4414) |
125 |
PPP1CC | oncoprotein | 12 | 0.394 | 22.725 | Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase STPPase_N (PF16891, IPR031675): Serine-threonine protein phosphatase N-terminal domain |
126 |
PPP4C | interactor | 4 | 0.500 | 1.952 | Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase STPPase_N (PF16891, IPR031675): Serine-threonine protein phosphatase N-terminal domain |
127 |
PPP4R1 | interactor | 4 | 0.500 | 1.833 | HEAT (PF02985, IPR000357): HEAT repeat Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region HEAT_2 (PF13646): HEAT repeats WRNPLPNID (PF15017): Putative WW-binding domain and destruction box |
128 |
PRKCZ | interactor | 12 | 0.509 | 15.808 | PB1 (PF00564, IPR000270, SM00666): PB1 domain Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain) |
129 |
PSEN1 | oncoprotein | 11 | 0.289 | 21.767 | Presenilin (PF01080, IPR001108): Presenilin LRRC37AB_C (PF14914, IPR029423): LRRC37A/B like protein 1 C-terminal domain |
130 |
PSEN2 | oncoprotein | 6 | 0.700 | 1.833 | Herpes_LMP1 (PF05297, IPR007961): Herpesvirus latent membrane protein 1 (LMP1) Presenilin (PF01080, IPR001108): Presenilin |
131 |
PSMB5 | interactor | 14 | 0.626 | 17.494 | Proteasome (PF00227, IPR001353): Proteasome subunit |
132 |
PSMC1 | interactor | 16 | 0.567 | 30.599 | AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA) AAA_3 (PF07726, IPR011703): ATPase family associated with various cellular activities (AAA) DivIC (PF04977, IPR007060): Septum formation initiator DUF815 (PF05673, IPR008533): Protein of unknown function (DUF815) Prot_ATP_ID_OB (PF16450, IPR032501): Proteasomal ATPase OB/ID domain |
133 |
PSMC2 | protein found in more fusions | 19 | 0.523 | 36.361 | AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA) |
134 |
PSMC3 | interactor | 21 | 0.411 | 65.985 | AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA) DUF3713 (PF12506, IPR022186): Protein of unknown function (DUF3713) JIP_LZII (PF16471, IPR032486): JNK-interacting protein leucine zipper II |
135 |
PSMD1 | interactor | 14 | 0.626 | 16.730 | PA26 (PF04636, IPR006730): PA26 p53-induced protein (sestrin) PC_rep (PF01851, IPR002015): Proteasome/cyclosome repeat HEAT_2 (PF13646): HEAT repeats |
136 |
PSMD12 | interactor | 16 | 0.571 | 25.096 | Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain PCI (PF01399, IPR000717, SM00088): PCI domain |
137 |
PSMD13 | interactor | 12 | 0.803 | 4.375 | Mitovir_RNA_pol (PF05919, IPR008686): Mitovirus RNA-dependent RNA polymerase PCI (PF01399, IPR000717, SM00088): PCI domain |
138 |
PSMD3 | interactor | 12 | 0.818 | 3.233 | Rpn3_C (PF08375, IPR013586): Proteasome regulatory subunit C-terminal TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat PCI (PF01399, IPR000717, SM00088): PCI domain Fis1_TPR_C (PF14853, IPR028061): Fis1 C-terminal tetratricopeptide repeat TSKS (PF15358, IPR028214): Testis-specific serine kinase substrate |
139 |
PSMD7 | interactor | 14 | 0.648 | 18.027 | JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg (PF13012, IPR024969): Maintenance of mitochondrial structure and function Auts2 (PF15336): Autism susceptibility gene 2 protein Coilin_N (PF15862, IPR031722): Coilin N-terminus |
140 |
RACK1 | suppressor | 12 | 0.382 | 19.403 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain |
141 |
RANBP9 | suppressor | 15 | 0.341 | 36.227 | Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator LisH (PF08513, IPR013720, SM00667): LisH SPRY (PF00622, IPR003877, SM00449): SPRY domain CLTH (PF10607, IPR024964): CTLH/CRA C-terminal to LisH motif domain |
142 |
RBCK1 | interactor | 27 | 0.311 | 105.646 | GAGA (PF09237, IPR015318): GAGA factor IBR (PF01485, IPR002867, SM00647): IBR domain, a half RING-finger domain ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger |
143 |
RCAN1 | interactor | 4 | 0.667 | 1.200 | Calcipressin (PF04847, IPR006931): Calcipressin |
144 |
RIPK2 | interactor | 22 | 0.462 | 42.869 | CARD (PF00619, IPR001315, SM00114): Caspase recruitment domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase |
145 |
RNF114 | protein found in more fusions | 12 | 0.364 | 16.701 | zf-Di19 (PF05605, IPR008598): Drought induced 19 protein (Di19), zinc-binding HypA (PF01155, IPR000688): Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger zf-RING_4 (PF14570): RING/Ubox like zinc-binding domain |
146 |
RNF166 | interactor | 9 | 0.250 | 12.832 | zf-Di19 (PF05605, IPR008598): Drought induced 19 protein (Di19), zinc-binding zinc-ribbons_6 (PF07191, IPR010807): zinc-ribbons Rad50_zn_hook (PF04423, IPR007517): Rad50 zinc hook motif UIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif zinc_ribbon_2 (PF13240, IPR026870): zinc-ribbon domain zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger zf-RING_4 (PF14570): RING/Ubox like zinc-binding domain |
147 |
RPTOR | protein found in more fusions | 17 | 0.400 | 36.375 | HEAT (PF02985, IPR000357): HEAT repeat WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1 ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain HEAT_2 (PF13646): HEAT repeats Raptor_N (PF14538, IPR029347): Raptor N-terminal CASPase like domain |
148 |
RRAGC | interactor | 4 | 1.000 | 0 | Gtr1_RagA (PF04670, IPR006762): Gtr1/RagA G protein conserved region |
149 |
RUNX1 | suppressor | 4 | 0.667 | 0.333 | Runt (PF00853, IPR013524): Runt domain RunxI (PF08504, IPR013711): Runx inhibition domain DUF3037 (PF11236, IPR021398): Protein of unknown function (DUF3037) |
150 |
RUSC1 | interactor | 4 | 0.667 | 0.321 | RUN (PF02759, IPR004012, SM00593): RUN domain MAGE_N (PF12440, IPR021072): Melanoma associated antigen family N terminal SH3_9 (PF14604, IPR001452): Variant SH3 domain |
151 |
SARM1 | interactor | 10 | 0.311 | 20.167 | Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat Carb_kinase (PF01256, IPR000631): Carbohydrate kinase SAM_2 (PF07647, IPR011510): SAM domain (Sterile alpha motif) HEAT_2 (PF13646): HEAT repeats TIR_2 (PF13676, IPR000157): TIR domain |
152 |
SDCBP | interactor | 9 | 0.278 | 18.841 | PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) |
153 |
SIGIRR | interactor | 6 | 0.600 | 1.819 | TIR (PF01582, IPR000157, SM00255): TIR domain Ig_3 (PF13927): Immunoglobulin domain |
154 |
SMURF1 | interactor | 24 | 0.194 | 117.325 | C2 (PF00168, IPR000008, SM00239): C2 domain WW (PF00397, IPR001202, SM00456): WW domain HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase) |
155 |
SNAP29 | protein found in more fusions | 2 | 0 | 0 | DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664) Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family V-SNARE_C (PF12352): Snare region anchored in the vesicle membrane C-terminus DUF5082 (PF16888, IPR031681): Domain of unknown function (DUF5082) |
156 |
SNCA | interactor | 18 | 0.375 | 47.342 | Synuclein (PF01387, IPR001058): Synuclein |
157 |
SOCS3 | suppressor | 6 | 0.533 | 3.848 | SH2 (PF00017, IPR000980, SM00252): SH2 domain SOCS_box (PF07525, IPR001496): SOCS box |
158 |
SPHK1 | interactor | 4 | 0.833 | 0.286 | DAGK_cat (PF00781, IPR001206, SM00046): Diacylglycerol kinase catalytic domain |
159 |
SPOP | suppressor | 8 | 0.333 | 6.650 | BACK (PF07707, IPR011705, SM00875): BTB And C-terminal Kelch BTB (PF00651, IPR013069, SM00225): BTB/POZ domain MATH (PF00917, IPR002083, SM00061): MATH domain |
160 |
SQSTM1 | oncoprotein | 38 | 0.164 | 401.225 | PB1 (PF00564, IPR000270, SM00666): PB1 domain ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type UBA_5 (PF16577, IPR015940): UBA domain |
161 |
SRC | oncoprotein | 25 | 0.319 | 95.546 | Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain |
162 |
STAMBP | interactor | 6 | 0.600 | 2.843 | USP8_dimer (PF08969, IPR015063): USP8 dimerisation domain JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease DUF3526 (PF12040, IPR021913): Domain of unknown function (DUF3526) |
163 |
STAT3 | suppressor | 18 | 0.272 | 61.901 | SH2 (PF00017, IPR000980, SM00252): SH2 domain STAT_alpha (PF01017, IPR013800): STAT protein, all-alpha domain STAT_bind (PF02864, IPR013801): STAT protein, DNA binding domain STAT_int (PF02865, IPR013799, SM00964): STAT protein, protein interaction domain |
164 |
STK26 | interactor | 4 | 0.667 | 0.400 | DUF1241 (PF06840, IPR009652): Protein of unknown function (DUF1241) Pkinase (PF00069, IPR000719): Protein kinase domain |
165 |
STRADB | interactor | 3 | 1.000 | 0 | Pkinase (PF00069, IPR000719): Protein kinase domain ASXH (PF13919, IPR028020): Asx homology domain |
166 |
STUB1 | suppressor | 45 | 0.201 | 477.102 | U-box (PF04564, IPR003613, SM00504): U-box domain ANAPC3 (PF12895): Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 (PF13414, IPR011990): TPR repeat TPR_20 (PF14561): Tetratricopeptide repeat |
167 |
SYK | suppressor | 19 | 0.288 | 71.090 | Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain |
168 |
TAB1 | interactor | 16 | 0.442 | 31.551 | PP2C (PF00481, IPR001932): Protein phosphatase 2C |
169 |
TAB2 | oncoprotein | 34 | 0.227 | 253.211 | CUE (PF02845, IPR003892, SM00546): CUE domain DivIC (PF04977, IPR007060): Septum formation initiator Mnd1 (PF03962, IPR005647): Mnd1 family zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others |
170 |
TAB3 | oncoprotein | 14 | 0.500 | 18.795 | CUE (PF02845, IPR003892, SM00546): CUE domain Tmemb_cc2 (PF10267, IPR019394): Predicted transmembrane and coiled-coil 2 protein zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others |
171 |
TANK | suppressor | 19 | 0.340 | 55.419 | DUF3713 (PF12506, IPR022186): Protein of unknown function (DUF3713) TBD (PF12845, IPR024581): TBD domain |
172 |
TARS | interactor | 2 | 1.000 | 0 | HGTP_anticodon (PF03129, IPR004154): Anticodon binding domain TGS (PF02824, IPR004095): TGS domain tRNA-synt_2b (PF00587, IPR002314): tRNA synthetase class II core domain (G, H, P, S and T) tRNA_SAD (PF07973, IPR012947, SM00863): Threonyl and Alanyl tRNA synthetase second additional domain |
173 |
TAX1BP1 | interactor | 8 | 0.571 | 4.704 | CALCOCO1 (PF07888, IPR012852): Calcium binding and coiled-coil domain (CALCOCO1) like zf-Di19 (PF05605, IPR008598): Drought induced 19 protein (Di19), zinc-binding Myc-LZ (PF02344, IPR003327): Myc leucine zipper domain PolyA_pol (PF01743, IPR002646): Poly A polymerase head domain Spc24 (PF08286, IPR013252): Spc24 subunit of Ndc80 zf-C2H2_4 (PF13894): C2H2-type zinc finger PRKG1_interact (PF15898, IPR031775): cGMP-dependent protein kinase interacting domain |
174 |
TDP2 | interactor | 9 | 0.361 | 13.682 | Exo_endo_phos (PF03372, IPR005135): Endonuclease/Exonuclease/phosphatase family DUF4150 (PF13665, IPR025425): Domain of unknown function (DUF4150) UBA_4 (PF14555): UBA-like domain |
175 |
TGFBR1 | oncoprotein | 15 | 0.267 | 40.844 | Activin_recp (PF01064, IPR000472): Activin types I and II receptor domain Pkinase (PF00069, IPR000719): Protein kinase domain TGF_beta_GS (PF08515, IPR003605, SM00467): Transforming growth factor beta type I GS-motif |
176 |
TGFBR2 | suppressor | 6 | 0.733 | 1.190 | ecTbetaR2 (PF08917, IPR015013): Transforming growth factor beta receptor 2 ectodomain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase |
177 |
TICAM1 | protein found in more fusions | 17 | 0.300 | 55.982 | Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator RHIM (PF12721, IPR025735): RIP homotypic interaction motif TIR_2 (PF13676, IPR000157): TIR domain |
178 |
TICAM2 | interactor | 7 | 0.381 | 9.252 | TIR_2 (PF13676, IPR000157): TIR domain |
179 |
TIFA | interactor | 5 | 0.500 | 1.476 | FHA (PF00498, IPR000253, SM00240): FHA domain |
180 |
TIRAP | interactor | 14 | 0.397 | 26.232 | TIR_2 (PF13676, IPR000157): TIR domain |
181 |
TJP2 | oncoprotein | 1 | 0 | 0 | PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) SH3_2 (PF07653, IPR011511): Variant SH3 domain Guanylate_kin (PF00625, IPR008145, SM00072): Guanylate kinase |
182 |
TLR3 | interactor | 9 | 0.444 | 11.086 | LRR_1 (PF00560, IPR001611): Leucine Rich Repeat LRRCT (PF01463, IPR000483, SM00082): Leucine rich repeat C-terminal domain LRRNT (PF01462, IPR000372, SM00013): Leucine rich repeat N-terminal domain TIR (PF01582, IPR000157, SM00255): TIR domain LRR_5 (PF13306, IPR026906): Leucine rich repeats (6 copies) LRR_8 (PF13855, IPR001611): Leucine rich repeat |
183 |
TLR4 | interactor | 15 | 0.324 | 43.760 | LRR_1 (PF00560, IPR001611): Leucine Rich Repeat TIR (PF01582, IPR000157, SM00255): TIR domain LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies) LRR_8 (PF13855, IPR001611): Leucine rich repeat LRR_9 (PF14580): Leucine-rich repeat |
184 |
TLR9 | interactor | 8 | 0.571 | 4.555 | LRR_1 (PF00560, IPR001611): Leucine Rich Repeat TIR (PF01582, IPR000157, SM00255): TIR domain LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies) LRR_6 (PF13516, IPR001611): Leucine Rich repeat LRR_8 (PF13855, IPR001611): Leucine rich repeat |
185 |
TNFAIP3 | suppressor | 26 | 0.347 | 102.261 | OTU (PF02338, IPR003323): OTU-like cysteine protease zf-A20 (PF01754, IPR002653, SM00259): A20-like zinc finger Thioredoxin_3 (PF13192, IPR012336): Thioredoxin domain |
186 |
TNFRSF11A | oncoprotein | 7 | 0.667 | 2.218 | Abi (PF02517, IPR003675): CAAX protease self-immunity DAG1 (PF05454, IPR008465): Dystroglycan (Dystrophin-associated glycoprotein 1) KIX (PF02172, IPR003101): KIX domain TNFR_c6 (PF00020, IPR001368, SM00208): TNFR/NGFR cysteine-rich region |
187 |
TNFRSF13B | oncoprotein | 6 | 0.600 | 3.098 | TACI-CRD2 (PF09305, IPR015384): TACI, cysteine-rich domain |
188 |
TNFRSF17 | oncoprotein | 4 | 0.833 | 0.118 | BCMA-Tall_bind (PF09257, IPR015337): BCMA, TALL-1 binding Adipogenin (PF15202, IPR027938): Adipogenin |
189 |
TNFRSF1A | oncoprotein | 26 | 0.367 | 98.224 | Death (PF00531, IPR000488, SM00005): Death domain TNFR_c6 (PF00020, IPR001368, SM00208): TNFR/NGFR cysteine-rich region |
190 |
TNFRSF1B | oncoprotein | 10 | 0.639 | 5.802 | TNFR_c6 (PF00020, IPR001368, SM00208): TNFR/NGFR cysteine-rich region |
191 |
TOLLIP | interactor | 17 | 0.258 | 55.375 | C2 (PF00168, IPR000008, SM00239): C2 domain CUE (PF02845, IPR003892, SM00546): CUE domain |
192 |
TOMM20 | interactor | 7 | 0.476 | 6.533 | RSN1_7TM (PF02714, IPR003864): Calcium-dependent channel, 7TM region, putative phosphate MAS20 (PF02064, IPR002056): MAS20 protein import receptor |
193 |
TOMM70 | interactor | 8 | 0.357 | 10.955 | PBP_GOBP (PF01395, IPR006170, SM00708): PBP/GOBP family TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat TPR_8 (PF13181, IPR019734): Tetratricopeptide repeat TPR_12 (PF13424): Tetratricopeptide repeat TPR_14 (PF13428): Tetratricopeptide repeat TPR_17 (PF13431): Tetratricopeptide repeat TPR_19 (PF14559): Tetratricopeptide repeat NRBF2_MIT (PF17169): MIT domain of nuclear receptor-binding factor 2 |
194 |
TRADD | interactor | 15 | 0.440 | 28.823 | Death (PF00531, IPR000488, SM00005): Death domain TRADD_N (PF09034, IPR009095): TRADD, N-terminal domain TPR_14 (PF13428): Tetratricopeptide repeat |
195 |
TRAF1 | oncoprotein | 35 | 0.273 | 206.100 | HypA (PF01155, IPR000688): Hydrogenase/urease nickel incorporation, metallochaperone, hypA SlyX (PF04102, IPR007236): SlyX TRAF_BIRC3_bd (PF16673, IPR032070): TNF receptor-associated factor BIRC3 binding domain |
196 |
TRAF2 | interactor | 71 | 0.148 | 1404.781 | MATH (PF00917, IPR002083, SM00061): MATH domain Sina (PF03145, IPR018121): Seven in absentia protein family SlyX (PF04102, IPR007236): SlyX zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger) zf-TRAF (PF02176, IPR001293): TRAF-type zinc finger TRAF_BIRC3_bd (PF16673, IPR032070): TNF receptor-associated factor BIRC3 binding domain zf-C3HC4_5 (PF17121, IPR001841): Zinc finger, C3HC4 type (RING finger) |
197 |
TRAF3IP1 | interactor | 3 | 1.000 | 0 | MIP-T3 (PF10243): Microtubule-binding protein MIP-T3 |
198 |
TRAF3IP2 | interactor | 17 | 0.358 | 45.376 | SEFIR (PF08357, IPR013568): SEFIR domain Trypan_PARP (PF05887, IPR008882): Procyclic acidic repetitive protein (PARP) |
199 |
TRAF4 | oncoprotein | 23 | 0.234 | 97.643 | MATH (PF00917, IPR002083, SM00061): MATH domain Sina (PF03145, IPR018121): Seven in absentia protein family zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger) zf-TRAF (PF02176, IPR001293): TRAF-type zinc finger |
200 |
TRAF5 | interactor | 27 | 0.194 | 151.534 | Sina (PF03145, IPR018121): Seven in absentia protein family zf-TRAF (PF02176, IPR001293): TRAF-type zinc finger zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger) zf-RING_4 (PF14570): RING/Ubox like zinc-binding domain HMMR_N (PF15905, IPR031787): Hyaluronan mediated motility receptor N-terminal Spc29 (PF17082, IPR031392): Spindle Pole Component 29 |
201 |
TRAFD1 | interactor | 3 | 0.667 | 0.333 | zf-Di19 (PF05605, IPR008598): Drought induced 19 protein (Di19), zinc-binding DM (PF00751, IPR001275, SM00301): DM DNA binding domain zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-C2H2_4 (PF13894): C2H2-type zinc finger zf-C2HC_2 (PF13913): zinc-finger of a C2HC-type |
202 |
TRAIP | interactor | 15 | 0.330 | 31.151 | Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein ORF6C (PF10552, IPR018878): ORF6C domain zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1 |
203 |
TRIM17 | interactor | 9 | 0.389 | 5.125 | NlpE (PF04170, IPR007298): NlpE N-terminal domain SPRY (PF00622, IPR003877, SM00449): SPRY domain zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger PRY (PF13765, IPR006574, SM00589): SPRY-associated domain zf-Nse (PF11789, IPR004181): Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 (PF15227): zinc finger of C3HC4-type, RING |
204 |
TRIM25 | protein found in more fusions | 14 | 0.295 | 29.070 | Fes1 (PF08609, IPR013918): Nucleotide exchange factor Fes1 Pox_Rif (PF03340, IPR005008): Poxvirus rifampicin resistance protein SPRY (PF00622, IPR003877, SM00449): SPRY domain zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger PRY (PF13765, IPR006574, SM00589): SPRY-associated domain zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger Prok-RING_4 (PF14447): Prokaryotic RING finger family 4 |
205 |
TRIM37 | oncoprotein | 12 | 0.382 | 14.589 | MATH (PF00917, IPR002083, SM00061): MATH domain zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger Kinetocho_Slk19 (PF12709, IPR024312): Central kinetochore-associated zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger) MRFAP1 (PF15155, IPR029254): MORF4 family-associated protein1 PRKG1_interact (PF15898, IPR031775): cGMP-dependent protein kinase interacting domain DUF5071 (PF16804, IPR031837): Domain of unknown function (DUF5071) |
206 |
TRIM38 | interactor | 12 | 0.273 | 21.013 | DUF342 (PF03961, IPR005646): Protein of unknown function (DUF342) SPRY (PF00622, IPR003877, SM00449): SPRY domain zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger PRY (PF13765, IPR006574, SM00589): SPRY-associated domain zf-C3HC4_4 (PF15227): zinc finger of C3HC4-type, RING |
207 |
UBC | protein found in more fusions | 86 | 0.113 | 2375.573 | ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family |
208 |
UBE2D1 | interactor | 29 | 0.230 | 140.423 | UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme |
209 |
UBE2D2 | oncoprotein | 29 | 0.259 | 128.877 | UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme |
210 |
UBE2D3 | interactor | 23 | 0.216 | 69.004 | UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme |
211 |
UBE2D4 | interactor | 11 | 0.222 | 10.282 | UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme |
212 |
UBE2E1 | protein found in more fusions | 15 | 0.198 | 27.133 | UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein |
213 |
UBE2I | interactor | 28 | 0.179 | 200.582 | UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme |
214 |
UBE2L3 | protein found in more fusions | 17 | 0.417 | 29.855 | UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme |
215 |
UBE2N | protein found in more fusions | 20 | 0.363 | 48.896 | UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme |
216 |
UBE2O | protein found in more fusions | 9 | 0.536 | 3.991 | BUD22 (PF09073, IPR015158): BUD22 UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme CCDC106 (PF15794, IPR031591): Coiled-coil domain-containing protein 106 |
217 |
UBE2V1 | interactor | 13 | 0.551 | 14.248 | UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme |
218 |
UBOX5 | interactor | 12 | 0.309 | 14.838 | U-box (PF04564, IPR003613, SM00504): U-box domain zf-RING_5 (PF14634, IPR001841): zinc-RING finger domain |
219 |
UCHL1 | suppressor | 13 | 0.385 | 24.867 | Peptidase_C12 (PF01088, IPR001578): Ubiquitin carboxyl-terminal hydrolase, family 1 |
220 |
UEVLD | interactor | 3 | 1.000 | 0 | Ldh_1_C (PF02866, IPR022383): lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N (PF00056, IPR001236): lactate/malate dehydrogenase, NAD binding domain UEV (PF05743, IPR008883): UEV domain |
221 |
ULK1 | protein found in more fusions | 11 | 0.356 | 19.641 | Pkinase (PF00069, IPR000719): Protein kinase domain DUF3543 (PF12063, IPR022708): Domain of unknown function (DUF3543) RCDG1 (PF15725, IPR031457): Renal cancer differentiation gene 1 protein |
222 |
USP1 | protein found in more fusions | 5 | 0.833 | 0.500 | UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase |
223 |
USP10 | protein found in more fusions | 12 | 0.382 | 21.098 | PAM2 (PF07145, IPR009818): Ataxin-2 C-terminal region UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase YukD (PF08817, IPR024962): WXG100 protein secretion system (Wss), protein YukD |
224 |
USP15 | oncoprotein | 23 | 0.294 | 95.329 | UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase DUSP (PF06337, IPR006615, SM00695): DUSP domain Ubiquitin_3 (PF14836, IPR028135): Ubiquitin-like domain |
225 |
USP2 | interactor | 18 | 0.314 | 69.740 | UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase |
226 |
USP20 | protein found in more fusions | 8 | 0.524 | 6.800 | UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase zf-UBP (PF02148, IPR001607, SM00290): Zn-finger in ubiquitin-hydrolases and other protein DUSP (PF06337, IPR006615, SM00695): DUSP domain |
227 |
USP21 | interactor | 15 | 0.407 | 28.675 | UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase |
228 |
USP33 | suppressor | 8 | 0.571 | 8.133 | UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase zf-UBP (PF02148, IPR001607, SM00290): Zn-finger in ubiquitin-hydrolases and other protein DUSP (PF06337, IPR006615, SM00695): DUSP domain |
229 |
USP39 | oncoprotein | 5 | 0.600 | 1.682 | UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase zf-UBP (PF02148, IPR001607, SM00290): Zn-finger in ubiquitin-hydrolases and other protein |
230 |
USP4 | oncoprotein | 14 | 0.359 | 28.230 | UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase DUSP (PF06337, IPR006615, SM00695): DUSP domain Ubiquitin_3 (PF14836, IPR028135): Ubiquitin-like domain |
231 |
USP5 | interactor | 8 | 0.536 | 3.534 | UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase zf-UBP (PF02148, IPR001607, SM00290): Zn-finger in ubiquitin-hydrolases and other protein |
232 |
USP7 | oncoprotein | 21 | 0.300 | 78.530 | MATH (PF00917, IPR002083, SM00061): MATH domain UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase USP7_ICP0_bdg (PF12436, IPR024729): ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 (PF14533, IPR029346): Ubiquitin-specific protease C-terminal |
233 |
VARS | interactor | 5 | 0.400 | 5.067 | Anticodon_1 (PF08264, IPR013155): Anticodon-binding domain of tRNA GST_C (PF00043, IPR004046): Glutathione S-transferase, C-terminal domain tRNA-synt_1 (PF00133, IPR002300): tRNA synthetases class I (I, L, M and V) Val_tRNA-synt_C (PF10458, IPR019499): Valyl tRNA synthetase tRNA binding arm SUIM_assoc (PF16619): Unstructured region C-term to UIM in Ataxin3 |
234 |
VCP | protein found in more fusions | 25 | 0.221 | 142.324 | AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA) CDC48_2 (PF02933, IPR004201, SM01072): Cell division protein 48 (CDC48), domain 2 CDC48_N (PF02359, IPR003338, SM01073): Cell division protein 48 (CDC48), N-terminal domain TniB (PF05621, IPR008868): Bacterial TniB protein Vps4_C (PF09336, IPR015415): Vps4 C terminal oligomerisation domain DUF3944 (PF13099, IPR025217): Domain of unknown function (DUF3944) |
235 |
VDAC1 | interactor | 7 | 0.381 | 9.317 | Porin_3 (PF01459, IPR027246): Eukaryotic porin |
236 |
VPS52 | interactor | 4 | 0.667 | 0.667 | Vps52 (PF04129, IPR007258): Vps52 / Sac2 family COG5 (PF10392, IPR019465): Golgi transport complex subunit 5 Sec3_C (PF09763, IPR019160): Exocyst complex component Sec3 |
237 |
WDFY3 | interactor | 3 | 0.667 | 0.333 | Beach (PF02138, IPR000409, SM01026): Beige/BEACH domain FYVE (PF01363, IPR000306, SM00064): FYVE zinc finger WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Laminin_G_3 (PF13385): Concanavalin A-like lectin/glucanases superfamily E3_UbLigase_R4 (PF13764, IPR025704): E3 ubiquitin-protein ligase UBR4 PH_BEACH (PF14844, IPR023362): PH domain associated with Beige/BEACH DUF4704 (PF15787, IPR031570): Domain of unknown function (DUF4704) DUF4800 (PF16057): Domain of unknown function (DUF4800) |
238 |
WDR34 | interactor | 4 | 1.000 | 0 | GTF2I (PF02946, IPR004212): GTF2I-like repeat WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain |
239 |
WDR5 | interactor | 9 | 0.333 | 12.336 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat |
240 |
WWP1 | oncoprotein | 10 | 0.556 | 4.439 | C2 (PF00168, IPR000008, SM00239): C2 domain WW (PF00397, IPR001202, SM00456): WW domain HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase) |
241 |
XIAP | interactor | 34 | 0.231 | 240.540 | BIR (PF00653, IPR001370, SM00238): Inhibitor of Apoptosis domain zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger) |
242 |
YBX1 | oncoprotein | 12 | 0.288 | 27.083 | CSD (PF00313, IPR002059): 'Cold-shock' DNA-binding domain PBP1_TM (PF14812, IPR032730): Transmembrane domain of transglycosylase PBP1 at N-terminal FXR_C1 (PF16096, IPR032172): Fragile X-related 1 protein C-terminal region 2 |
243 |
YES1 | oncoprotein | 7 | 0.333 | 9.100 | Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain YdjC (PF04794, IPR006879): YdjC-like protein SH3_1 (PF00018, IPR001452, SM00326): SH3 domain |
244 |
ZC3H12A | interactor | 8 | 0.524 | 5.987 | RNase_Zc3h12a (PF11977, IPR021869): Zc3h12a-like Ribonuclease NYN domain zf-CCCH_2 (PF14608): RNA-binding, Nab2-type zinc finger |
245 |
ZFAND5 | interactor | 5 | 0.700 | 0.512 | zf-A20 (PF01754, IPR002653, SM00259): A20-like zinc finger zf-AN1 (PF01428, IPR000058, SM00154): AN1-like Zinc finger FAM53 (PF15242, IPR029356): Family of FAM53 |
246 |
ZMYND11 | suppressor | 10 | 0.472 | 10.770 | DUF1002 (PF06207, IPR009343): Protein of unknown function (DUF1002) DUF1353 (PF07087, IPR010767): Protein of unknown function (DUF1353) PWWP (PF00855, IPR000313, SM00293): PWWP domain zf-MYND (PF01753, IPR002893): MYND finger zf-UBR (PF02207, IPR003126): Putative zinc finger in N-recognin (UBR box) Bromodomain (PF00439, IPR001487, SM00297): Bromodomain |
247 |
ZNF675 | interactor | 1 | 0 | 0 | KRAB (PF01352, IPR001909, SM00349): KRAB box zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain |
248 |
ZRANB1 | interactor | 2 | 1.000 | 0 | Copper-fist (PF00649, IPR001083, SM01090): Copper fist DNA binding domain OTU (PF02338, IPR003323): OTU-like cysteine protease zf-Sec23_Sec24 (PF04810, IPR006895): Sec23/Sec24 zinc finger zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others |