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Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)103
The number (and %) of the onco-proteins27 (26.21 %)
The number (and %) of the tumor suppressors16 (15.53 %)
Total number of binary PPIs (saturation %)491 (9.35 %)
The number (and %) of affected PPIs103 (20.98 %)
The number of possible different fusions19
PPI diameter2
PPI radius1
The average degree of PPI9.010
Assortativity coefficient-0.2891
The network average Clustering coefficient0.633
The number (and %) of a zero Clustering coefficients7 (6.80 %)
The number (and %) of a zero Betweenness Centrality31 (30.10 %)

ACTIVE INTERACTORS


List of the fusions

PPI for parental proteins: TPM1 All fusions
: CN274732; BE005428;
Proteins found in more fusions TPM2 (see 1 fusions); AHCYL1 (see 3 fusions); MAD1L1 (see 3 fusions); TPM1 (see 2 fusions); TPM2/TPM3 (see 1 fusions); TPM2/MYH9 (see 1 fusions); EGFR (see 2 fusions); ACTN2 (see 1 fusions); STUB1 (see 1 fusions); ACTN1 (see 3 fusions); THOC1 (see 3 fusions); TPM3 (see 2 fusions); LRRK2 (see 1 fusions); CDC37 (see 2 fusions); TPM1/TPM2 (see 1 fusions); TNNT1 (see 1 fusions); SP1 (see 1 fusions); TP53 (see 3 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 TPM1parental protein1030.0707626.883Tropomyosin (PF00261, IPR000533): Tropomyosin
Tropomyosin_1 (PF12718, IPR000533): Tropomyosin like
2 ABI2suppressor31.0000Abi_HHR (PF07815, IPR012849): Abl-interactor HHR
NUDE_C (PF04880, IPR006964): NUDE protein, C-terminal conserved region
SH3_9 (PF14604, IPR001452): Variant SH3 domain
TMEM171 (PF15471, IPR029173): Transmembrane protein family 171
ATP-synt_ab_Xtn (PF16886, IPR031686): ATPsynthase alpha/beta subunit N-term extension
3 ACTA2interactor110.32727.690Actin (PF00022, IPR004000, SM00268): Actin
4 ACTC1interactor40.5001.186Actin (PF00022, IPR004000, SM00268): Actin
5 ACTN1protein found in more fusions210.56841.134CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
Dak2 (PF02734, IPR004007, SM01120): DAK2 domain
EFhand_Ca_insen (PF08726, IPR014837): Ca2+ insensitive EF hand
Spectrin (PF00435, IPR002017): Spectrin repeat
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
Uds1 (PF15456, IPR029191): Up-regulated During Septation
6 ACTN2protein found in more fusions140.35942.452CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
EFhand_Ca_insen (PF08726, IPR014837): Ca2+ insensitive EF hand
Nsp1_C (PF05064, IPR007758): Nsp1-like C-terminal region
Spectrin (PF00435, IPR002017): Spectrin repeat
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
7 ACTN4interactor220.56345.435CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
EFhand_Ca_insen (PF08726, IPR014837): Ca2+ insensitive EF hand
Spectrin (PF00435, IPR002017): Spectrin repeat
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
Uds1 (PF15456, IPR029191): Up-regulated During Septation
8 AHCYL1suppressor110.37818.152AdoHcyase (PF05221, IPR000043, SM00996): S-adenosyl-L-homocysteine hydrolase
AdoHcyase_NAD (PF00670, IPR015878, SM00997): S-adenosyl-L-homocysteine hydrolase, NAD binding domain
DUF515 (PF04415, IPR007509): Protein of unknown function (DUF515)
Big_3_5 (PF16640, IPR032109): Bacterial Ig-like domain (group 3)
9 ANLNoncoprotein160.7928.858Anillin (PF08174, IPR012966): Cell division protein anillin
PH (PF00169, IPR001849, SM00233): PH domain
Anillin_N (PF16018, IPR031970): Anillin N-terminus
10 APPL2interactor21.0000PH (PF00169, IPR001849, SM00233): PH domain
PID (PF00640, IPR006020, SM00462): Phosphotyrosine interaction domain (PTB/PID)
BAR_3 (PF16746): BAR domain of APPL family
11 ATF2oncoprotein50.6670.952bZIP_1 (PF00170, IPR004827): bZIP transcription factor
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
12 ATP5F1interactor60.8670.583Mt_ATP-synt_B (PF05405, IPR008688): Mitochondrial ATP synthase B chain precursor (ATP-synt_B)
DUF2105 (PF09878, IPR019212): Predicted membrane protein (DUF2105)
13 BRCA1suppressor120.45521.099BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain
zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger)
BRCT_assoc (PF12820, IPR025994): Serine-rich domain associated with BRCT
14 C10orf2interactor100T2SSE (PF00437, IPR001482): Type II/IV secretion system protein
SMC_N (PF02463, IPR003395): RecF/RecN/SMC N terminal domain
AAA_25 (PF13481): AAA domain
15 C1orf216interactor21.0000DUF4653 (PF15546, IPR027812): Domain of unknown function (DUF4653)
16 CAGE1oncoprotein100ZapB (PF06005, IPR009252): Cell division protein ZapB
Spectrin (PF00435, IPR002017): Spectrin repeat
DUF2209 (PF09974, IPR014514): Uncharacterized protein conserved in archaea (DUF2209)
Tropomyosin_1 (PF12718, IPR000533): Tropomyosin like
CAGE1 (PF15066, IPR029381): Cancer-associated gene protein 1 family
17 CAPZA2interactor210.66725.515F-actin_cap_A (PF01267, IPR002189): F-actin capping protein alpha subunit
18 CCDC102Ainteractor21.0000IncA (PF04156, IPR007285): IncA protein
Myosin_tail_1 (PF01576, IPR002928): Myosin tail
THOC7 (PF05615, IPR008501): Tho complex subunit 7
Uds1 (PF15456, IPR029191): Up-regulated During Septation
PRKG1_interact (PF15898, IPR031775): cGMP-dependent protein kinase interacting domain
19 CDC37protein found in more fusions110.35621.586CDC37_C (PF08564, IPR013873, SM01069): Cdc37 C terminal domain
CDC37_M (PF08565, IPR013874, SM01070): Cdc37 Hsp90 binding domain
CDC37_N (PF03234, IPR013855, SM01071): Cdc37 N terminal kinase binding
Rho_Binding (PF08912, IPR015008): Rho Binding
TMF_DNA_bd (PF12329, IPR022092): TATA element modulatory factor 1 DNA binding
20 CDK2suppressor250.388112.795Kdo (PF06293, IPR010440): Lipopolysaccharide kinase (Kdo/WaaP) family
Pkinase (PF00069, IPR000719): Protein kinase domain
21 CFAP97interactor30.6670.400DUF755 (PF05501, IPR008474): Domain of unknown function (DUF755)
KIAA1430 (PF13879, IPR029488): KIAA1430 homologue
GH97_C (PF14509, IPR029483): Glycosyl-hydrolase 97 C-terminal, oligomerisation
22 CKBinteractor70.8570.954ATP-gua_Ptrans (PF00217, IPR022414): ATP:guanido phosphotransferase, C-terminal catalytic domain
ATP-gua_PtransN (PF02807, IPR022413): ATP:guanido phosphotransferase, N-terminal domain
23 CNN1suppressor100Calponin (PF00402, IPR000557): Calponin family repeat
CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
24 CNN2interactor50.6002.233Calponin (PF00402, IPR000557): Calponin family repeat
CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
25 CNTLNinteractor31.0000APG6 (PF04111, IPR007243): Autophagy protein Apg6
ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16)
CALCOCO1 (PF07888, IPR012852): Calcium binding and coiled-coil domain (CALCOCO1) like
DUF745 (PF05335, IPR007999): Protein of unknown function (DUF745)
HrpB7 (PF09486, IPR013392): Bacterial type III secretion protein (HrpB7)
Cnn_1N (PF07989, IPR012943): Centrosomin N-terminal motif 1
Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein
Spc24 (PF08286, IPR013252): Spc24 subunit of Ndc80
TSC22 (PF01166, IPR000580): TSC-22/dip/bun family
Uso1_p115_C (PF04871, IPR006955): Uso1 / p115 like vesicle tethering protein, C terminal region
Cep57_CLD_2 (PF14197, IPR025925): Centrosome localisation domain of PPC89
PRKG1_interact (PF15898, IPR031775): cGMP-dependent protein kinase interacting domain
26 COX4I1interactor50.9000.500COX4 (PF02936, IPR004203): Cytochrome c oxidase subunit IV
27 COX5Ainteractor41.0000COX5A (PF02284, IPR003204): Cytochrome c oxidase subunit Va
28 CROCCinteractor100APG6 (PF04111, IPR007243): Autophagy protein Apg6
COG2 (PF06148, IPR024602): COG (conserved oligomeric Golgi) complex component, COG2
DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664)
DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972)
Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein
Rho_Binding (PF08912, IPR015008): Rho Binding
Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein
CENP-F_leu_zip (PF10473, IPR019513): Leucine-rich repeats of kinetochore protein Cenp-F/LEK1
KxDL (PF10241, IPR019371): Uncharacterized conserved protein
SOGA (PF11365, IPR027881): Protein SOGA
ADIP (PF11559, IPR021622): Afadin- and alpha -actinin-Binding
KfrA_N (PF11740, IPR021104): Plasmid replication region DNA-binding N-term
DUF3450 (PF11932, IPR016866): Protein of unknown function (DUF3450)
TMF_DNA_bd (PF12329, IPR022092): TATA element modulatory factor 1 DNA binding
Tropomyosin_1 (PF12718, IPR000533): Tropomyosin like
DUF4404 (PF14357, IPR025516): Domain of unknown function (DUF4404)
DUF4472 (PF14739, IPR029329): Domain of unknown function (DUF4472)
Rootletin (PF15035): Ciliary rootlet component, centrosome cohesion
29 DBN1oncoprotein210.57643.384Pinin_SDK_memA (PF04696, IPR006786): pinin/SDK/memA/ protein conserved region
Cofilin_ADF (PF00241, IPR002108, SM00102): Cofilin/tropomyosin-type actin-binding protein
CAF-1_p150 (PF11600): Chromatin assembly factor 1 complex p150 subunit, N-terminal
MSA-2c (PF12238, IPR021060): Merozoite surface antigen 2c
30 DLG5interactor100Takusan (PF04822, IPR006907): Takusan
DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972)
EMP24_GP25L (PF01105, IPR009038): emp24/gp25L/p24 family/GOLD
Occludin_ELL (PF07303, IPR010844): Occludin homology domain
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
Guanylate_kin (PF00625, IPR008145, SM00072): Guanylate kinase
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
GAS (PF13851, IPR025593): Growth-arrest specific micro-tubule binding
Cep57_CLD_2 (PF14197, IPR025925): Centrosome localisation domain of PPC89
dbPDZ_assoc (PF16610): Unstructured region between two PDZ domains on Dlg5
31 DNAJC7interactor60.4676.417DnaJ (PF00226, IPR001623, SM00271): DnaJ domain
TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat
Rapsyn_N (PF10579, IPR019568): Rapsyn N-terminal myristoylation and linker region
ANAPC3 (PF12895): Anaphase-promoting complex, cyclosome, subunit 3
TPR_11 (PF13414, IPR011990): TPR repeat
TPR_17 (PF13431): Tetratricopeptide repeat
32 EGFRoncoprotein160.35244.240Furin-like (PF00757, IPR006211): Furin-like cysteine rich region
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
Recep_L_domain (PF01030, IPR000494): Receptor L domain
GAPT (PF11770, IPR021082): GRB2-binding adapter (GAPT)
GF_recep_IV (PF14843, IPR032778): Growth factor receptor domain IV
33 ELAVL1oncoprotein200.205112.132RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
34 ENDOGinteractor21.0000Pyr_redox_2 (PF07992, IPR023753): Pyridine nucleotide-disulphide oxidoreductase
35 ERGoncoprotein40.6671.333Ets (PF00178, IPR000418, SM00413): Ets-domain
SAM_2 (PF07647, IPR011510): SAM domain (Sterile alpha motif)
SAM_PNT (PF02198, IPR003118, SM00251): Sterile alpha motif (SAM)/Pointed domain
36 ETFAinteractor30.6671.000ETF (PF01012, IPR014730, SM00893): Electron transfer flavoprotein domain
ETF_alpha (PF00766, IPR014731): Electron transfer flavoprotein FAD-binding domain
37 EXOC4oncoprotein30.6670.667DUF948 (PF06103, IPR009293): Bacterial protein of unknown function (DUF948)
Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family
Sec8_exocyst (PF04048, IPR007191): Sec8 exocyst complex component specific domain
Vps51 (PF08700): Vps51/Vps67
38 FLNAsuppressor200.66821.794CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
Filamin (PF00630, IPR017868): Filamin/ABP280 repeat
39 FOXK1interactor21.0000Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator
FHA (PF00498, IPR000253, SM00240): FHA domain
Forkhead (PF00250, IPR001766, SM00339): Forkhead domain
40 GOLGA2interactor30.6671.000ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16)
Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein
Rootletin (PF15035): Ciliary rootlet component, centrosome cohesion
GOLGA2L5 (PF15070, IPR024858): Putative golgin subfamily A member 2-like protein 5
41 GOLGA3interactor31.0000ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16)
Bap31 (PF05529, IPR008417): B-cell receptor-associated protein 31-like
Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein
Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein
CENP-F_leu_zip (PF10473, IPR019513): Leucine-rich repeats of kinetochore protein Cenp-F/LEK1
G-gamma (PF00631, IPR015898, SM00224): GGL domain
SOGA (PF11365, IPR027881): Protein SOGA
TMF_TATA_bd (PF12325, IPR022091): TATA element modulatory factor 1 TATA binding
TMF_DNA_bd (PF12329, IPR022092): TATA element modulatory factor 1 DNA binding
GAS (PF13851, IPR025593): Growth-arrest specific micro-tubule binding
DUF4200 (PF13863, IPR025252): Domain of unknown function (DUF4200)
KASH_CCD (PF14662, IPR028168): Coiled-coil region of CCDC155 or KASH
Rootletin (PF15035): Ciliary rootlet component, centrosome cohesion
TolA_bind_tri (PF16331, IPR032519): TolA binding protein trimerisation
42 HOMER1interactor30.6670.500WH1 (PF00568, IPR000697, SM00461): WH1 domain
TMF_TATA_bd (PF12325, IPR022091): TATA element modulatory factor 1 TATA binding
GAS (PF13851, IPR025593): Growth-arrest specific micro-tubule binding
43 HSP90B1suppressor80.5007.733CobT (PF06213, IPR006538): Cobalamin biosynthesis protein CobT
HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
HSP90 (PF00183, IPR001404): Hsp90 protein
Sigma70_ner (PF04546, IPR007631): Sigma-70, non-essential region
44 IKBKGinteractor90.4649.883CENP-H (PF05837, IPR008426): Centromere protein H (CENP-H)
DUF725 (PF05267, IPR007931): Protein of unknown function (DUF725)
NEMO (PF11577, IPR021063): NF-kappa-B essential modulator NEMO
LLC1 (PF14945, IPR020339): Normal lung function maintenance, Low in Lung Cancer 1 protein
CC2-LZ (PF16516, IPR032419): Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator
45 IQGAP1interactor200.70016.379CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
DUF87 (PF01935, IPR002789): Domain of unknown function DUF87
IDEAL (PF08858, IPR014957, SM00914): IDEAL domain
IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif
RasGAP (PF00616, IPR001936, SM00323): GTPase-activator protein for Ras-like GTPase
RasGAP_C (PF03836, IPR000593): RasGAP C-terminus
WW (PF00397, IPR001202, SM00456): WW domain
46 JUNDoncoprotein30.6670.286bZIP_1 (PF00170, IPR004827): bZIP transcription factor
Jun (PF03957, IPR005643): Jun-like transcription factor
47 KLHL21interactor100BACK (PF07707, IPR011705, SM00875): BTB And C-terminal Kelch
BTB (PF00651, IPR013069, SM00225): BTB/POZ domain
Kelch_1 (PF01344, IPR006652, SM00612): Kelch motif
Kelch_3 (PF13415): Galactose oxidase, central domain
Kelch_6 (PF13964): Kelch motif
48 KXD1interactor21.0000KxDL (PF10241, IPR019371): Uncharacterized conserved protein
49 LRCH3interactor41.0000CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
LRR_1 (PF00560, IPR001611): Leucine Rich Repeat
LRR_8 (PF13855, IPR001611): Leucine rich repeat
50 LRRK2oncoprotein120.45515.336Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
ATP-synt_ab (PF00006, IPR000194): ATP synthase alpha/beta family, nucleotide-binding domain
DUF1043 (PF06295, IPR009386): Protein of unknown function (DUF1043)
T2SSE (PF00437, IPR001482): Type II/IV secretion system protein
Roc (PF08477, IPR013684): Ras of Complex, Roc, domain of DAPkinase
Pkinase (PF00069, IPR000719): Protein kinase domain
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies)
PQQ_2 (PF13360, IPR002372): PQQ-like domain
LRR_8 (PF13855, IPR001611): Leucine rich repeat
COR (PF16095, IPR032171): C-terminal of Roc, COR, domain
51 MAD1L1suppressor31.0000MAD (PF05557, IPR008672): Mitotic checkpoint protein
Atg14 (PF10186, IPR018791): Vacuolar sorting 38 and autophagy-related subunit 14
52 MDC1suppressor60.8000.689FHA (PF00498, IPR000253, SM00240): FHA domain
DUF3274 (PF11678, IPR021692): Protein of unknown function (DUF3274)
Yop-YscD_cpl (PF16697, IPR032030): Inner membrane component of T3SS, cytoplasmic domain
RTT107_BRCT_5 (PF16770, IPR001357): Regulator of Ty1 transposition protein 107 BRCT domain
53 MGEA5oncoprotein40.6670.900NAGidase (PF07555, IPR011496): beta-N-acetylglucosaminidase
54 MYH1oncoprotein21.0000IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif
Myosin_N (PF02736, IPR004009): Myosin N-terminal SH3-like domain
Myosin_tail_1 (PF01576, IPR002928): Myosin tail
XhlA (PF10779, IPR019715): Haemolysin XhlA
Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain)
55 MYH2interactor50.8000.667IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif
Myosin_N (PF02736, IPR004009): Myosin N-terminal SH3-like domain
Myosin_tail_1 (PF01576, IPR002928): Myosin tail
XhlA (PF10779, IPR019715): Haemolysin XhlA
Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain)
56 MYH4interactor21.0000IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif
Myosin_N (PF02736, IPR004009): Myosin N-terminal SH3-like domain
Myosin_tail_1 (PF01576, IPR002928): Myosin tail
XhlA (PF10779, IPR019715): Haemolysin XhlA
Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain)
57 MYH6interactor41.0000IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif
Myosin_N (PF02736, IPR004009): Myosin N-terminal SH3-like domain
Myosin_tail_1 (PF01576, IPR002928): Myosin tail
Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain)
DUF5082 (PF16888, IPR031681): Domain of unknown function (DUF5082)
58 MYH7Binteractor60.8670.686Myosin_N (PF02736, IPR004009): Myosin N-terminal SH3-like domain
Myosin_tail_1 (PF01576, IPR002928): Myosin tail
YkuI_C (PF10388, IPR018842): EAL-domain associated signalling protein domain
Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain)
59 MYH8interactor21.0000IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif
Myosin_N (PF02736, IPR004009): Myosin N-terminal SH3-like domain
Myosin_tail_1 (PF01576, IPR002928): Myosin tail
XhlA (PF10779, IPR019715): Haemolysin XhlA
Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain)
60 MYH9suppressor250.55070.435IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif
Myosin_N (PF02736, IPR004009): Myosin N-terminal SH3-like domain
Myosin_tail_1 (PF01576, IPR002928): Myosin tail
Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain)
61 MYO18Ainteractor170.8463.549Vfa1 (PF08432, IPR013640): AAA-ATPase Vps4-associated protein 1
IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif
Myosin_tail_1 (PF01576, IPR002928): Myosin tail
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein
CENP-F_leu_zip (PF10473, IPR019513): Leucine-rich repeats of kinetochore protein Cenp-F/LEK1
Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain)
BST2 (PF16716, IPR024886): Bone marrow stromal antigen 2
62 MYO19interactor160.8921.925IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif
Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain)
63 MYOCinteractor40.6671.000IncA (PF04156, IPR007285): IncA protein
OLF (PF02191, IPR003112, SM00284): Olfactomedin-like domain
64 NDUFB10interactor41.0000NDUFB10 (PF10249, IPR019377): NADH-ubiquinone oxidoreductase subunit 10
65 NEBoncoprotein31.0000Peptidase_M24 (PF00557, IPR001714): Metallopeptidase family M24
Nebulin (PF00880, IPR000900, SM00227): Nebulin repeat
Shal-type (PF11601, IPR021645): Shal-type voltage-gated potassium channels, N-terminal
DUF3410 (PF11890, IPR024531): Domain of unknown function (DUF3410)
DUF3417 (PF11897, IPR024517): Protein of unknown function (DUF3417)
G-patch_2 (PF12656, IPR026822): DExH-box splicing factor binding site
NFRKB_winged (PF14465, IPR025220): NFRKB Winged Helix-like
SH3_9 (PF14604, IPR001452): Variant SH3 domain
66 NUDCD2interactor30.6671.000CS (PF04969, IPR007052): CS domain
DUF3110 (PF11360, IPR021503): Protein of unknown function (DUF3110)
67 PAN2interactor160.50036.887RNase_T (PF00929, IPR013520): Exonuclease
UCH_1 (PF13423, IPR001394): Ubiquitin carboxyl-terminal hydrolase
WD40_like (PF17005, IPR031544): WD40-like domain
68 PARK2suppressor120.40019.874IBR (PF01485, IPR002867, SM00647): IBR domain, a half RING-finger domain
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
69 PDLIM7interactor140.7148.482LIM (PF00412, IPR001781, SM00132): LIM domain
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
zinc_ribbon_10 (PF10058, IPR019273): Predicted integral membrane zinc-ribbon metal-binding protein
DUF4749 (PF15936, IPR031847): Domain of unknown function (DUF4749)
70 PPP1CBinteractor200.72115.167Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase
STPPase_N (PF16891, IPR031675): Serine-threonine protein phosphatase N-terminal domain
71 PPP4R2interactor21.0000BT1 (PF03092, IPR004324): BT1 family
PPP4R2 (PF09184, IPR015267): PPP4R2
72 PPP6R3interactor50.4004.786SAPS (PF04499, IPR007587): SIT4 phosphatase-associated protein
73 RBM15oncoprotein30.6670.667RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
SPOC (PF07744, IPR012921): SPOC domain
Apt1 (PF10351, IPR019443): Golgi-body localisation protein domain
74 RBPJinteractor30.6670.286BTD (PF09270, IPR015350): Beta-trefoil DNA-binding domain
LAG1-DNAbind (PF09271, IPR015351): LAG1, DNA binding
TIG (PF01833, IPR002909): IPT/TIG domain
75 RPS3interactor50.7001.134KH_2 (PF07650, IPR004044): KH domain
Ribosomal_S3_C (PF00189, IPR001351): Ribosomal protein S3, C-terminal domain
76 RUFY2interactor100bZIP_1 (PF00170, IPR004827): bZIP transcription factor
Trimer_CC (PF08954, IPR015049, SM01167): Trimerisation motif
DUF641 (PF04859, IPR006943): Plant protein of unknown function (DUF641)
DUF724 (PF05266, IPR007930): Protein of unknown function (DUF724)
FYVE (PF01363, IPR000306, SM00064): FYVE zinc finger
RUN (PF02759, IPR004012, SM00593): RUN domain
SlyX (PF04102, IPR007236): SlyX
TMF_TATA_bd (PF12325, IPR022091): TATA element modulatory factor 1 TATA binding
GIT_CC (PF16559, IPR032352): GIT coiled-coil Rho guanine nucleotide exchange factor
77 SCLT1oncoprotein40.5002.333DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664)
DUF641 (PF04859, IPR006943): Plant protein of unknown function (DUF641)
DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972)
SlyX (PF04102, IPR007236): SlyX
XhlA (PF10779, IPR019715): Haemolysin XhlA
TMF_TATA_bd (PF12325, IPR022091): TATA element modulatory factor 1 TATA binding
Imm7 (PF15585, IPR028965): Immunity protein 7
CCCAP (PF15964, IPR031887): Centrosomal colon cancer autoantigen protein family
DUF5082 (PF16888, IPR031681): Domain of unknown function (DUF5082)
78 SEC23Ainteractor30.6670.667Gelsolin (PF00626, IPR007123): Gelsolin repeat
Sec23_BS (PF08033, IPR012990): Sec23/Sec24 beta-sandwich domain
Sec23_helical (PF04815, IPR006900): Sec23/Sec24 helical domain
Sec23_trunk (PF04811, IPR006896): Sec23/Sec24 trunk domain
zf-Sec23_Sec24 (PF04810, IPR006895): Sec23/Sec24 zinc finger
APP_E2 (PF12925, IPR024329): E2 domain of amyloid precursor protein
79 SF3B1oncoprotein50.6003.333Dopey_N (PF04118, IPR007249): Dopey, N-terminal
HEAT (PF02985, IPR000357): HEAT repeat
SF3b1 (PF08920, IPR015016): Splicing factor 3B subunit 1
UNC45-central (PF11701, IPR024660): Myosin-binding striated muscle assembly central
Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region
HEAT_EZ (PF13513): HEAT-like repeat
HEAT_2 (PF13646): HEAT repeats
80 SF3B2interactor60.4675.867DUF382 (PF04037, IPR007180): Domain of unknown function (DUF382)
PAPA-1 (PF04795, IPR006880): PAPA-1-like conserved region
PSP (PF04046, IPR006568, SM00581): PSP
SAP (PF02037, IPR003034, SM00513): SAP domain
Usp (PF00582, IPR006016): Universal stress protein family
Med19 (PF10278, IPR019403): Mediator of RNA pol II transcription subunit 19
Vma12 (PF11712, IPR021013): Endoplasmic reticulum-based factor for assembly of V-ATPase
FAM176 (PF14851): FAM176 family
WRNPLPNID (PF15017): Putative WW-binding domain and destruction box
81 SHTN1interactor60.5002.638Asp-B-Hydro_N (PF05279, IPR007943): Aspartyl beta-hydroxylase N-terminal region
VIT1 (PF01988, IPR008217): VIT family
Pinin_SDK_memA (PF04696, IPR006786): pinin/SDK/memA/ protein conserved region
Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein
BLOC1_2 (PF10046, IPR019269): Biogenesis of lysosome-related organelles complex-1 subunit 2
Atg14 (PF10186, IPR018791): Vacuolar sorting 38 and autophagy-related subunit 14
DUF3484 (PF11983, IPR021873): Membrane-attachment and polymerisation-promoting switch
Dscam_C (PF12355, IPR021012): Down syndrome cell adhesion molecule C terminal
PRKG1_interact (PF15898, IPR031775): cGMP-dependent protein kinase interacting domain
PRIMA1 (PF16101): Proline-rich membrane anchor 1
82 SORDinteractor80.38111.167ADH_N (PF08240, IPR013154): Alcohol dehydrogenase GroES-like domain
ADH_zinc_N (PF00107, IPR013149): Zinc-binding dehydrogenase
ADH_zinc_N_2 (PF13602): Zinc-binding dehydrogenase
83 SP1protein found in more fusions140.47428.221zf-Di19 (PF05605, IPR008598): Drought induced 19 protein (Di19), zinc-binding
Herpes_capsid (PF06112, IPR009299): Gammaherpesvirus capsid protein
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
Miga (PF10265, IPR019392): Mitoguardin
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
84 SPTBN1suppressor150.72414.917CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
COG2 (PF06148, IPR024602): COG (conserved oligomeric Golgi) complex component, COG2
DUF1764 (PF08576, IPR013885): Eukaryotic protein of unknown function (DUF1764)
Spectrin (PF00435, IPR002017): Spectrin repeat
PH_9 (PF15410): Pleckstrin homology domain
85 SRXN1interactor60.8001.019ParBc (PF02195, IPR003115): ParB-like nuclease domain
86 STUB1suppressor140.30843.402U-box (PF04564, IPR003613, SM00504): U-box domain
ANAPC3 (PF12895): Anaphase-promoting complex, cyclosome, subunit 3
TPR_11 (PF13414, IPR011990): TPR repeat
TPR_20 (PF14561): Tetratricopeptide repeat
87 SULT1A1interactor70.7142.252Sulfotransfer_1 (PF00685, IPR000863): Sulfotransferase domain
88 SYCE1interactor21.0000CENP-Q (PF13094, IPR025212): CENP-Q, a CENPA-CAD centromere complex subunit
SYCE1 (PF15233, IPR026676): Synaptonemal complex central element protein 1
89 SYNPOinteractor170.76515.733Calsarcin (PF05556, IPR008438): Calcineurin-binding protein (Calsarcin)
90 TFPToncoprotein31.0000GIT_CC (PF16559, IPR032352): GIT coiled-coil Rho guanine nucleotide exchange factor
91 TGFBR1oncoprotein40.5002.400Activin_recp (PF01064, IPR000472): Activin types I and II receptor domain
Pkinase (PF00069, IPR000719): Protein kinase domain
TGF_beta_GS (PF08515, IPR003605, SM00467): Transforming growth factor beta type I GS-motif
92 THOC1protein found in more fusions60.5004.500Death (PF00531, IPR000488, SM00005): Death domain
efThoc1 (PF11957, IPR021861): THO complex subunit 1 transcription elongation factor
93 THOC2interactor21.0000Sec62 (PF03839, IPR004728): Translocation protein Sec62
Tho2 (PF11262, IPR021418): Transcription factor/nuclear export subunit protein 2
Thoc2 (PF11732, IPR021726): Transcription- and export-related complex subunit
DUF3915 (PF13054, IPR025026): Protein of unknown function (DUF3915)
THOC2_N (PF16134, IPR032302): THO complex subunit 2 N-terminus
94 TNNI1interactor50.7003.000Troponin (PF00992, IPR001978): Troponin
95 TNNT1protein found in more fusions31.0000Troponin (PF00992, IPR001978): Troponin
DUF4050 (PF13259, IPR025124): Protein of unknown function (DUF4050)
96 TNNT2interactor21.0000Vfa1 (PF08432, IPR013640): AAA-ATPase Vps4-associated protein 1
Troponin (PF00992, IPR001978): Troponin
DUF4770 (PF15994, IPR031935): Domain of unknown function (DUF4770)
97 TP53suppressor230.325103.739DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region
P53 (PF00870, IPR011615): P53 DNA-binding domain
P53_tetramer (PF07710, IPR010991): P53 tetramerisation motif
98 TPM2protein found in more fusions310.338198.316DASH_Spc19 (PF08287, IPR013251): Spc19
Tropomyosin (PF00261, IPR000533): Tropomyosin
Tropomyosin_1 (PF12718, IPR000533): Tropomyosin like
99 TPM3oncoprotein400.227420.776Tropomyosin (PF00261, IPR000533): Tropomyosin
Tropomyosin_1 (PF12718, IPR000533): Tropomyosin like
100 TPM4oncoprotein340.314238.133Tropomyosin (PF00261, IPR000533): Tropomyosin
Tropomyosin_1 (PF12718, IPR000533): Tropomyosin like
101 TSSC4suppressor30.6671.000TSSC4 (PF15264, IPR029338): Tumour suppressing sub-chromosomal transferable candidate 4
102 YWHAQinteractor110.38220.84314-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
103 ZYXsuppressor60.4675.119DUF1180 (PF06679, IPR009565): Protein of unknown function (DUF1180)
LIM (PF00412, IPR001781, SM00132): LIM domain
DUF2757 (PF10955, IPR020115): Protein of unknown function (DUF2757)

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