1 |
TNFRSF1A | parental protein | 101 | 0.099 | 6412.783 | Death (PF00531, IPR000488, SM00005): Death domain TNFR_c6 (PF00020, IPR001368, SM00208): TNFR/NGFR cysteine-rich region |
2 |
ADAM17 | interactor | 3 | 0.667 | 0.667 | Pep_M12B_propep (PF01562, IPR002870): Reprolysin family propeptide Reprolysin (PF01421, IPR001590): Reprolysin (M12B) family zinc metalloprotease Disintegrin (PF00200, IPR001762, SM00050): Disintegrin Reprolysin_5 (PF13688): Metallo-peptidase family M12 ADAM17_MPD (PF16698, IPR032029): Membrane-proximal domain, switch, for ADAM17 |
3 |
ARHGDIA | interactor | 15 | 0.791 | 7.702 | Rho_GDI (PF02115, IPR000406): RHO protein GDP dissociation inhibitor |
4 |
ATF6 | interactor | 2 | 0 | 0 | bZIP_1 (PF00170, IPR004827): bZIP transcription factor DUF2749 (PF10907, IPR024475): Protein of unknown function (DUF2749) |
5 |
BAG4 | interactor | 3 | 0.667 | 0.667 | BAG (PF02179, IPR003103, SM00264): BAG domain DMP12 (PF16779, IPR031891): DNA-mimic protein |
6 |
BCL10 | suppressor | 13 | 0.591 | 11.971 | CARD (PF00619, IPR001315, SM00114): Caspase recruitment domain |
7 |
BID | oncoprotein | 15 | 0.791 | 8.074 | BID (PF06393, IPR010479): BH3 interacting domain (BID) |
8 |
BIRC2 | oncoprotein | 23 | 0.433 | 61.622 | BIR (PF00653, IPR001370, SM00238): Inhibitor of Apoptosis domain CARD (PF00619, IPR001315, SM00114): Caspase recruitment domain zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger) |
9 |
BIRC3 | oncoprotein | 21 | 0.500 | 41.354 | BIR (PF00653, IPR001370, SM00238): Inhibitor of Apoptosis domain CARD (PF00619, IPR001315, SM00114): Caspase recruitment domain zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger) |
10 |
BRE | oncoprotein | 4 | 0.500 | 2.000 | BRE (PF06113, IPR010358): Brain and reproductive organ-expressed protein (BRE) |
11 |
CASP10 | interactor | 19 | 0.614 | 24.508 | DED (PF01335, IPR001875, SM00031): Death effector domain Peptidase_C14 (PF00656, IPR011600): Caspase domain |
12 |
CASP2 | suppressor | 13 | 0.333 | 29.421 | CARD (PF00619, IPR001315, SM00114): Caspase recruitment domain Peptidase_C14 (PF00656, IPR011600): Caspase domain |
13 |
CASP7 | interactor | 9 | 0.643 | 5.919 | Peptidase_C14 (PF00656, IPR011600): Caspase domain PRIMA1 (PF16101): Proline-rich membrane anchor 1 |
14 |
CASP8 | suppressor | 32 | 0.370 | 157.860 | DED (PF01335, IPR001875, SM00031): Death effector domain Peptidase_C14 (PF00656, IPR011600): Caspase domain |
15 |
CAV1 | suppressor | 14 | 0.330 | 36.476 | Caveolin (PF01146, IPR001612): Caveolin |
16 |
CBL | suppressor | 14 | 0.551 | 16.569 | Cbl_N (PF02262, IPR003153): CBL proto-oncogene N-terminal domain 1 Cbl_N2 (PF02761, IPR014741): CBL proto-oncogene N-terminus, EF hand-like domain Cbl_N3 (PF02762, IPR014742): CBL proto-oncogene N-terminus, SH2-like domain UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain Prok-RING_4 (PF14447): Prokaryotic RING finger family 4 zf-RING_4 (PF14570): RING/Ubox like zinc-binding domain |
17 |
CHUK | suppressor | 24 | 0.439 | 62.833 | Pkinase (PF00069, IPR000719): Protein kinase domain IKKbetaNEMObind (PF12179, IPR022007): I-kappa-kinase-beta NEMO binding domain |
18 |
CLIP3 | interactor | 5 | 0.800 | 0.667 | Ank (PF00023, IPR002110, SM00248): Ankyrin repeat CAP_GLY (PF01302, IPR000938, SM01052): CAP-Gly domain Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) |
19 |
CRADD | interactor | 3 | 0.667 | 0.400 | CARD (PF00619, IPR001315, SM00114): Caspase recruitment domain Death (PF00531, IPR000488, SM00005): Death domain |
20 |
CSNK1A1L | interactor | 3 | 1.000 | 0 | Pkinase (PF00069, IPR000719): Protein kinase domain |
21 |
CYLD | suppressor | 11 | 0.600 | 9.776 | CAP_GLY (PF01302, IPR000938, SM01052): CAP-Gly domain UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase zf-HIT (PF04438, IPR007529): HIT zinc finger CYLD_phos_site (PF16607): Phosphorylation region of CYLD, unstructured |
22 |
DAB2IP | suppressor | 5 | 0.700 | 1.667 | C2 (PF00168, IPR000008, SM00239): C2 domain PH_2 (PF08458, IPR013666): Plant pleckstrin homology-like region RasGAP (PF00616, IPR001936, SM00323): GTPase-activator protein for Ras-like GTPase DUF3498 (PF12004, IPR021887): Domain of unknown function (DUF3498) |
23 |
DAPK1 | suppressor | 5 | 0.667 | 1.667 | ABC_tran (PF00005, IPR003439): ABC transporter Death (PF00531, IPR000488, SM00005): Death domain Roc (PF08477, IPR013684): Ras of Complex, Roc, domain of DAPkinase Pkinase (PF00069, IPR000719): Protein kinase domain Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) AAA_23 (PF13476): AAA domain Ank_5 (PF13857): Ankyrin repeats (many copies) COR (PF16095, IPR032171): C-terminal of Roc, COR, domain |
24 |
DAXX | oncoprotein | 8 | 0.619 | 4.133 | Daxx (PF03344, IPR005012): Daxx N-terminal Rassf1C-interacting domain Merozoite_SPAM (PF07133, IPR010784): Merozoite surface protein (SPAM) Nop14 (PF04147, IPR007276): Nop14-like family RF-1 (PF00472, IPR000352): RF-1 domain Vpu (PF00558, IPR008187): Vpu protein DUF3391 (PF11871, IPR021812): Domain of unknown function (DUF3391) |
25 |
EGFR | oncoprotein | 27 | 0.274 | 149.546 | Furin-like (PF00757, IPR006211): Furin-like cysteine rich region Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase Recep_L_domain (PF01030, IPR000494): Receptor L domain GAPT (PF11770, IPR021082): GRB2-binding adapter (GAPT) GF_recep_IV (PF14843, IPR032778): Growth factor receptor domain IV |
26 |
ELAVL1 | oncoprotein | 16 | 0.257 | 56.060 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
27 |
EZR | protein found in more fusions | 16 | 0.705 | 14.182 | DUF106 (PF01956, IPR002809): Integral membrane protein DUF106 ERM (PF00769, IPR011259): Ezrin/radixin/moesin family FERM_C (PF09380, IPR018980): FERM C-terminal PH-like domain FERM_M (PF00373, IPR019748): FERM central domain FERM_N (PF09379, IPR018979): FERM N-terminal domain |
28 |
FADD | suppressor | 24 | 0.435 | 82.595 | Death (PF00531, IPR000488, SM00005): Death domain DED (PF01335, IPR001875, SM00031): Death effector domain Hpt (PF01627, IPR008207, SM00073): Hpt domain |
29 |
FANCD2 | oncoprotein | 4 | 0.500 | 1.567 | FancD2 (PF14631, IPR029448): Fanconi anaemia protein FancD2 nuclease |
30 |
FAS | suppressor | 26 | 0.360 | 132.999 | Death (PF00531, IPR000488, SM00005): Death domain TNFR_c6 (PF00020, IPR001368, SM00208): TNFR/NGFR cysteine-rich region Stn1_C (PF12659, IPR024263): Telomere capping C-terminal wHTH |
31 |
FASLG | interactor | 17 | 0.588 | 34.552 | PAP_PilO (PF06864, IPR009663): Pilin accessory protein (PilO) TNF (PF00229, IPR006052, SM00207): TNF(Tumour Necrosis Factor) family PRIMA1 (PF16101): Proline-rich membrane anchor 1 |
32 |
FYN | oncoprotein | 17 | 0.383 | 38.554 | Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain |
33 |
GRB2 | oncoprotein | 23 | 0.277 | 125.362 | SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain DUF5093 (PF17011, IPR031533): Domain of unknown function (DUF5093) |
34 |
GYS2 | interactor | 2 | 1.000 | 0 | Glycogen_syn (PF05693, IPR008631): Glycogen synthase |
35 |
HNRNPD | oncoprotein | 9 | 0.321 | 15.500 | CBFNT (PF08143, IPR012956): CBFNT (NUC161) domain NID (PF07292, IPR009909): Nmi/IFP 35 domain (NID) RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Keratin_2_head (PF16208, IPR032444): Keratin type II head |
36 |
HRG | suppressor | 1 | 0 | 0 | Cystatin (PF00031, IPR000010, SM00043): Cystatin domain |
37 |
HSPA8 | oncoprotein | 11 | 0.364 | 28.419 | HSP70 (PF00012, IPR013126): Hsp70 protein |
38 |
IKBKB | protein found in more fusions | 23 | 0.424 | 69.523 | FliT (PF05400, IPR008622): Flagellar protein FliT Glyco_hydro_65m (PF03632, IPR005195): Glycosyl hydrolase family 65 central catalytic domain Pkinase (PF00069, IPR000719): Protein kinase domain SlyX (PF04102, IPR007236): SlyX ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family IKKbetaNEMObind (PF12179, IPR022007): I-kappa-kinase-beta NEMO binding domain |
39 |
IKBKG | interactor | 31 | 0.363 | 143.757 | CENP-H (PF05837, IPR008426): Centromere protein H (CENP-H) DUF725 (PF05267, IPR007931): Protein of unknown function (DUF725) NEMO (PF11577, IPR021063): NF-kappa-B essential modulator NEMO LLC1 (PF14945, IPR020339): Normal lung function maintenance, Low in Lung Cancer 1 protein CC2-LZ (PF16516, IPR032419): Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator |
40 |
JAK1 | oncoprotein | 5 | 0.833 | 0.333 | FERM_M (PF00373, IPR019748): FERM central domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain |
41 |
JAK2 | oncoprotein | 11 | 0.600 | 7.800 | FERM_M (PF00373, IPR019748): FERM central domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain |
42 |
KHDRBS1 | protein found in more fusions | 11 | 0.489 | 12.755 | KH_1 (PF00013, IPR004088, SM00322): KH domain Qua1 (PF16274, IPR032571): Qua1 domain Sam68-YY (PF16568, IPR032335): Tyrosine-rich domain of Sam68 |
43 |
LTA | oncoprotein | 3 | 0.667 | 1.000 | TNF (PF00229, IPR006052, SM00207): TNF(Tumour Necrosis Factor) family |
44 |
LTB | oncoprotein | 2 | 1.000 | 0 | TNF (PF00229, IPR006052, SM00207): TNF(Tumour Necrosis Factor) family |
45 |
MADD | suppressor | 1 | 0 | 0 | DENN (PF02141, IPR001194, SM00799): DENN (AEX-3) domain HD-ZIP_N (PF04618, IPR006712): HD-ZIP protein N terminus uDENN (PF03456, IPR005113, SM00800): uDENN domain |
46 |
MAGEH1 | interactor | 1 | 0 | 0 | MAGE (PF01454, IPR002190): MAGE family |
47 |
MAP3K7 | oncoprotein | 17 | 0.533 | 21.743 | Mnd1 (PF03962, IPR005647): Mnd1 family Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase |
48 |
MAPK1 | oncoprotein | 6 | 0.400 | 4.583 | Pkinase (PF00069, IPR000719): Protein kinase domain |
49 |
MAPK8 | oncoprotein | 19 | 0.549 | 44.314 | DUF530 (PF04409, IPR007503): Protein of unknown function (DUF530) Pkinase (PF00069, IPR000719): Protein kinase domain |
50 |
MSN | oncoprotein | 14 | 0.872 | 4.650 | DUF883 (PF05957, IPR010279): Bacterial protein of unknown function (DUF883) ERM (PF00769, IPR011259): Ezrin/radixin/moesin family FERM_C (PF09380, IPR018980): FERM C-terminal PH-like domain FERM_M (PF00373, IPR019748): FERM central domain FERM_N (PF09379, IPR018979): FERM N-terminal domain |
51 |
MUC1 | oncoprotein | 8 | 0.607 | 5.400 | SEA (PF01390, IPR000082, SM00200): SEA domain Shisa (PF13908, IPR026910): Wnt and FGF inhibitory regulator Collectrin (PF16959, IPR031588): Renal amino acid transporter |
52 |
MYOC | interactor | 2 | 0 | 0 | IncA (PF04156, IPR007285): IncA protein OLF (PF02191, IPR003112, SM00284): Olfactomedin-like domain |
53 |
NOL3 | oncoprotein | 7 | 0.800 | 1.352 | CARD (PF00619, IPR001315, SM00114): Caspase recruitment domain Trypan_PARP (PF05887, IPR008882): Procyclic acidic repetitive protein (PARP) |
54 |
NSMAF | interactor | 1 | 0 | 0 | Beach (PF02138, IPR000409, SM01026): Beige/BEACH domain GRAM (PF02893, IPR004182, SM00568): GRAM domain NABP (PF07990, IPR012940): Nucleic acid binding protein NABP WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain PH_BEACH (PF14844, IPR023362): PH domain associated with Beige/BEACH |
55 |
OPTN | protein found in more fusions | 8 | 0.571 | 4.841 | ARD (PF03079, IPR004313): ARD/ARD' family bZIP_1 (PF00170, IPR004827): bZIP transcription factor HALZ (PF02183, IPR003106, SM00340): Homeobox associated leucine zipper Uso1_p115_C (PF04871, IPR006955): Uso1 / p115 like vesicle tethering protein, C terminal region NEMO (PF11577, IPR021063): NF-kappa-B essential modulator NEMO CC2-LZ (PF16516, IPR032419): Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator |
56 |
PHAX | interactor | 1 | 0 | 0 | RNA_GG_bind (PF10258, IPR019385): PHAX RNA-binding domain FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 |
57 |
PIK3CA | oncoprotein | 7 | 0.524 | 6.817 | PI3K_C2 (PF00792, IPR002420, SM00142): Phosphoinositide 3-kinase C2 PI3K_p85B (PF02192, IPR003113, SM00143): PI3-kinase family, p85-binding domain PI3K_rbd (PF00794, IPR000341, SM00144): PI3-kinase family, ras-binding domain PI3Ka (PF00613, IPR001263, SM00145): Phosphoinositide 3-kinase family, accessory domain (PIK domain) DUF2321 (PF10083, IPR016891): Uncharacterized protein conserved in bacteria (DUF2321) PI3_PI4_kinase (PF00454, IPR000403, SM00146): Phosphatidylinositol 3- and 4-kinase |
58 |
PIK3R1 | oncoprotein | 16 | 0.505 | 27.995 | RhoGAP (PF00620, IPR000198, SM00324): RhoGAP domain SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_2 (PF07653, IPR011511): Variant SH3 domain PI3K_P85_iSH2 (PF16454, IPR032498): Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain |
59 |
PIP4K2B | protein found in more fusions | 2 | 0 | 0 | PIP5K (PF01504, IPR002498): Phosphatidylinositol-4-phosphate 5-Kinase |
60 |
PPP1CA | suppressor | 9 | 0.361 | 18.352 | Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase STPPase_N (PF16891, IPR031675): Serine-threonine protein phosphatase N-terminal domain |
61 |
PRDX3 | interactor | 5 | 0.500 | 1.500 | AhpC-TSA (PF00578, IPR000866): AhpC/TSA family 1-cysPrx_C (PF10417, IPR019479): C-terminal domain of 1-Cys peroxiredoxin |
62 |
PRKCB | suppressor | 9 | 0.571 | 5.502 | C2 (PF00168, IPR000008, SM00239): C2 domain Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain) |
63 |
PRKCD | suppressor | 9 | 0.429 | 8.386 | Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain) |
64 |
PSMD2 | oncoprotein | 6 | 0.400 | 7.333 | PC_rep (PF01851, IPR002015): Proteasome/cyclosome repeat THAP (PF05485, IPR006612, SM00980): THAP domain HEAT_2 (PF13646): HEAT repeats |
65 |
RHOA | suppressor | 16 | 0.650 | 21.512 | Ras (PF00071, IPR001806, SM00173): Ras family |
66 |
RIPK1 | protein found in more fusions | 33 | 0.347 | 165.174 | Death (PF00531, IPR000488, SM00005): Death domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase RHIM (PF12721, IPR025735): RIP homotypic interaction motif |
67 |
RIPK2 | interactor | 14 | 0.756 | 5.035 | CARD (PF00619, IPR001315, SM00114): Caspase recruitment domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase |
68 |
RIPK3 | interactor | 8 | 0.750 | 2.917 | Pkinase (PF00069, IPR000719): Protein kinase domain TrbM (PF07424, IPR009989): TrbM MSA-2c (PF12238, IPR021060): Merozoite surface antigen 2c RHIM (PF12721, IPR025735): RIP homotypic interaction motif |
69 |
RNF31 | interactor | 14 | 0.692 | 8.111 | Auto_anti-p27 (PF06677, IPR009563): Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) IBR (PF01485, IPR002867, SM00647): IBR domain, a half RING-finger domain PUB (PF09409, IPR018997): PUB domain TF_Zn_Ribbon (PF08271, IPR013137): TFIIB zinc-binding zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others zf-RING_4 (PF14570): RING/Ubox like zinc-binding domain HOIP-UBA (PF16678, IPR032065): UB-associated-like domain of HOIP or E3 ubiquitin-protein ligase |
70 |
RNF8 | suppressor | 4 | 0.667 | 0.200 | FHA (PF00498, IPR000253, SM00240): FHA domain Jnk-SapK_ap_N (PF09744, IPR019143): JNK_SAPK-associated protein-1 zf-C2H2_2 (PF12756, IPR015880): C2H2 type zinc-finger (2 copies) zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger) DUF4665 (PF15679, IPR031389): Domain of unknown function (DUF4665) |
71 |
SGTA | interactor | 2 | 1.000 | 0 | TOM20_plant (PF06552, IPR010547): Plant specific mitochondrial import receptor subunit TOM20 TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat XPC-binding (PF09280, IPR015360): XPC-binding domain TPR_17 (PF13431): Tetratricopeptide repeat SGTA_dimer (PF16546, IPR032374): Homodimerisation domain of SGTA |
72 |
SH3KBP1 | protein found in more fusions | 16 | 0.438 | 29.620 | Tmemb_cc2 (PF10267, IPR019394): Predicted transmembrane and coiled-coil 2 protein SH3_9 (PF14604, IPR001452): Variant SH3 domain |
73 |
SHARPIN | interactor | 10 | 0.806 | 1.590 | DUF1518 (PF07469, IPR010011, SM01151): Domain of unknown function (DUF1518) ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others Sharpin_PH (PF16764, IPR031912): Sharpin PH domain |
74 |
SOS1 | oncoprotein | 8 | 0.786 | 2.000 | Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4 PH (PF00169, IPR001849, SM00233): PH domain RasGEF (PF00617, IPR001895, SM00147): RasGEF domain RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain RasGEF_N (PF00618, IPR000651, SM00229): RasGEF N-terminal motif |
75 |
SRC | oncoprotein | 21 | 0.400 | 53.183 | Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain |
76 |
STAMBP | interactor | 3 | 0.667 | 0.400 | USP8_dimer (PF08969, IPR015063): USP8 dimerisation domain JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease DUF3526 (PF12040, IPR021913): Domain of unknown function (DUF3526) |
77 |
STAT1 | suppressor | 11 | 0.289 | 21.336 | SH2 (PF00017, IPR000980, SM00252): SH2 domain STAT_alpha (PF01017, IPR013800): STAT protein, all-alpha domain STAT_bind (PF02864, IPR013801): STAT protein, DNA binding domain STAT_int (PF02865, IPR013799, SM00964): STAT protein, protein interaction domain STAT1_TAZ2bind (PF12162, IPR022752): STAT1 TAZ2 binding domain |
78 |
SUMO1 | interactor | 8 | 0.524 | 6.090 | Rad60-SLD (PF11976, IPR022617): Ubiquitin-2 like Rad60 SUMO-like |
79 |
SYK | suppressor | 11 | 0.600 | 8.314 | Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain |
80 |
SYNCRIP | interactor | 6 | 0.533 | 5.500 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 (PF11608, IPR024582): Limkain b1 |
81 |
TNF | oncoprotein | 24 | 0.391 | 80.994 | TNF (PF00229, IPR006052, SM00207): TNF(Tumour Necrosis Factor) family |
82 |
TNFAIP3 | suppressor | 18 | 0.647 | 14.844 | OTU (PF02338, IPR003323): OTU-like cysteine protease zf-A20 (PF01754, IPR002653, SM00259): A20-like zinc finger Thioredoxin_3 (PF13192, IPR012336): Thioredoxin domain |
83 |
TNFRSF10B | suppressor | 18 | 0.621 | 23.088 | Death (PF00531, IPR000488, SM00005): Death domain RskA (PF10099, IPR018764): Anti-sigma-K factor rskA TNFR_c6 (PF00020, IPR001368, SM00208): TNFR/NGFR cysteine-rich region |
84 |
TNFRSF1B | oncoprotein | 16 | 0.362 | 54.825 | TNFR_c6 (PF00020, IPR001368, SM00208): TNFR/NGFR cysteine-rich region |
85 |
TNFSF13 | interactor | 4 | 0.667 | 0.667 | DUF1049 (PF06305, IPR010445): Protein of unknown function (DUF1049) TNF (PF00229, IPR006052, SM00207): TNF(Tumour Necrosis Factor) family |
86 |
TRADD | interactor | 22 | 0.381 | 66.565 | Death (PF00531, IPR000488, SM00005): Death domain TRADD_N (PF09034, IPR009095): TRADD, N-terminal domain TPR_14 (PF13428): Tetratricopeptide repeat |
87 |
TRAF1 | oncoprotein | 21 | 0.568 | 27.526 | HypA (PF01155, IPR000688): Hydrogenase/urease nickel incorporation, metallochaperone, hypA SlyX (PF04102, IPR007236): SlyX TRAF_BIRC3_bd (PF16673, IPR032070): TNF receptor-associated factor BIRC3 binding domain |
88 |
TRAF2 | interactor | 33 | 0.385 | 129.002 | MATH (PF00917, IPR002083, SM00061): MATH domain Sina (PF03145, IPR018121): Seven in absentia protein family SlyX (PF04102, IPR007236): SlyX zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger) zf-TRAF (PF02176, IPR001293): TRAF-type zinc finger TRAF_BIRC3_bd (PF16673, IPR032070): TNF receptor-associated factor BIRC3 binding domain zf-C3HC4_5 (PF17121, IPR001841): Zinc finger, C3HC4 type (RING finger) |
89 |
TRAF3 | oncoprotein | 18 | 0.412 | 39.864 | ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16) S-AdoMet_synt_M (PF02772, IPR022629): S-adenosylmethionine synthetase, central domain zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger) zf-TRAF (PF02176, IPR001293): TRAF-type zinc finger zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain MPS2 (PF17060, IPR031433): Monopolar spindle protein 2 Spc29 (PF17082, IPR031392): Spindle Pole Component 29 |
90 |
TRAF6 | protein found in more fusions | 26 | 0.367 | 99.830 | SlyX (PF04102, IPR007236): SlyX zf-TRAF (PF02176, IPR001293): TRAF-type zinc finger zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger) |
91 |
TRAP1 | oncoprotein | 1 | 0 | 0 | HSP90 (PF00183, IPR001404): Hsp90 protein HATPase_c_3 (PF13589): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase |
92 |
TRPC1 | interactor | 8 | 0.476 | 8.667 | Ion_trans (PF00520, IPR005821): Ion transport protein TRP_2 (PF08344, IPR013555): Transient receptor ion channel II Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_4 (PF13637): Ankyrin repeats (many copies) |
93 |
TRPC4 | protein found in more fusions | 5 | 1.000 | 0 | Gp-FAR-1 (PF05823, IPR008632): Nematode fatty acid retinoid binding protein (Gp-FAR-1) IncA (PF04156, IPR007285): IncA protein Ion_trans (PF00520, IPR005821): Ion transport protein TRP_2 (PF08344, IPR013555): Transient receptor ion channel II Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_5 (PF13857): Ankyrin repeats (many copies) |
94 |
TRPC4AP | interactor | 10 | 0.556 | 16.882 | Put_DNA-bind_N (PF06971, IPR009718): Putative DNA-binding protein N-terminus DUF3689 (PF12463, IPR022162): Protein of unknown function (DUF3689) |
95 |
TRPC5 | interactor | 4 | 1.000 | 0 | Ank (PF00023, IPR002110, SM00248): Ankyrin repeat Gp-FAR-1 (PF05823, IPR008632): Nematode fatty acid retinoid binding protein (Gp-FAR-1) Ion_trans (PF00520, IPR005821): Ion transport protein TRP_2 (PF08344, IPR013555): Transient receptor ion channel II Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_5 (PF13857): Ankyrin repeats (many copies) |
96 |
UBE2I | interactor | 15 | 0.319 | 39.180 | UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme |
97 |
UBQLN1 | protein found in more fusions | 5 | 0.500 | 1.786 | Clathrin-link (PF09268, IPR015348): Clathrin, heavy-chain linker UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain XPC-binding (PF09280, IPR015360): XPC-binding domain ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family Fur_reg_FbpB (PF13040, IPR025004): Fur-regulated basic protein B FAM199X (PF15814, IPR029672): Protein family FAM199X |
98 |
UCHL1 | suppressor | 6 | 0.533 | 3.309 | Peptidase_C12 (PF01088, IPR001578): Ubiquitin carboxyl-terminal hydrolase, family 1 |
99 |
USP2 | interactor | 9 | 0.750 | 1.863 | UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase |
100 |
USP4 | oncoprotein | 7 | 0.933 | 0.118 | UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase DUSP (PF06337, IPR006615, SM00695): DUSP domain Ubiquitin_3 (PF14836, IPR028135): Ubiquitin-like domain |
101 |
VWA9 | interactor | 1 | 0 | 0 | VWA_2 (PF13519, IPR002035): von Willebrand factor type A domain |