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Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)97
The number (and %) of the onco-proteins28 (28.87 %)
The number (and %) of the tumor suppressors13 (13.40 %)
Total number of binary PPIs (saturation %)380 (8.16 %)
The number (and %) of affected PPIs97 (25.53 %)
The number of possible different fusions19
PPI diameter2
PPI radius1
The average degree of PPI6.969
Assortativity coefficient-0.4533
The network average Clustering coefficient0.449
The number (and %) of a zero Clustering coefficients32 (32.99 %)
The number (and %) of a zero Betweenness Centrality48 (49.48 %)

ACTIVE INTERACTORS


List of the fusions

PPI for parental proteins: TNF All fusions
: AI880081;
Proteins found in more fusions OPTN (see 1 fusions); HNRNPD (see 1 fusions); TAB2 (see 1 fusions); TNF (see 1 fusions); POU2F1 (see 1 fusions); RIPK1 (see 1 fusions); LYN (see 1 fusions); HSPB1 (see 3 fusions); MAP3K7 (see 7 fusions); IKBKB (see 2 fusions); UBC (see 1 fusions); RAC1 (see 1 fusions); FYN (see 1 fusions); CLU (see 5 fusions); UBE2N (see 1 fusions); B4GALT1 (see 2 fusions); LAMP2 (see 1 fusions); TNFRSF1A (see 2 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 TNFparental protein970.0537513.557TNF (PF00229, IPR006052, SM00207): TNF(Tumour Necrosis Factor) family
2 ABCB6interactor100ABC_membrane (PF00664, IPR001140): ABC transporter transmembrane region
ABC_tran (PF00005, IPR003439): ABC transporter
MTABC_N (PF16185, IPR032410): Mitochondrial ABC-transporter N-terminal five TM region
3 ACP2interactor21.0000His_Phos_2 (PF00328, IPR000560): Histidine phosphatase superfamily (branch 2)
4 AGO2interactor50.7000.872ArgoL1 (PF08699, IPR014811, SM01163): Argonaute linker 1 domain
PAZ (PF02170, IPR003100, SM00949): PAZ domain
Piwi (PF02171, IPR003165, SM00950): Piwi domain
ArgoN (PF16486, IPR032474): N-terminal domain of argonaute
ArgoMid (PF16487, IPR032473): Mid domain of argonaute
ArgoL2 (PF16488, IPR032472): Argonaute linker 2 domain
5 B4GALT1protein found in more fusions31.0000Glyco_transf_7C (PF02709, IPR027791): N-terminal domain of galactosyltransferase
Glyco_transf_7N (PF13733, IPR027995): N-terminal region of glycosyl transferase group 7
6 B4GALT5oncoprotein21.0000Glyco_transf_7C (PF02709, IPR027791): N-terminal domain of galactosyltransferase
Glyco_transf_7N (PF13733, IPR027995): N-terminal region of glycosyl transferase group 7
7 BDH1interactor100adh_short (PF00106, IPR002198): short chain dehydrogenase
DUF1776 (PF08643, IPR013952): Fungal family of unknown function (DUF1776)
8 BGNoncoprotein21.0000LRRNT (PF01462, IPR000372, SM00013): Leucine rich repeat N-terminal domain
LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies)
LRR_8 (PF13855, IPR001611): Leucine rich repeat
9 BIRC2oncoprotein130.60612.802BIR (PF00653, IPR001370, SM00238): Inhibitor of Apoptosis domain
CARD (PF00619, IPR001315, SM00114): Caspase recruitment domain
zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
10 BTRConcoprotein150.40733.029WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Beta-TrCP_D (PF12125, IPR021977, SM01028): D domain of beta-TrCP
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
F-box-like (PF12937, IPR001810): F-box-like
11 CAPNS1interactor21.0000EF-hand_1 (PF00036, IPR002048, SM00054): EF hand
EF-hand_6 (PF13405, IPR002048): EF-hand domain
EF-hand_8 (PF13833, IPR002048): EF-hand domain pair
12 CASP8suppressor140.62811.676DED (PF01335, IPR001875, SM00031): Death effector domain
Peptidase_C14 (PF00656, IPR011600): Caspase domain
13 CAV1suppressor90.52812.252Caveolin (PF01146, IPR001612): Caveolin
14 CDC42oncoprotein70.6672.483Ras (PF00071, IPR001806, SM00173): Ras family
15 CDYLinteractor21.0000Chromo (PF00385, IPR023780, SM00298): Chromo (CHRromatin Organisation MOdifier) domain
ECH_1 (PF00378, IPR001753): Enoyl-CoA hydratase/isomerase
ECH_2 (PF16113, IPR032259): Enoyl-CoA hydratase/isomerase
16 CELSR2interactor1007tm_2 (PF00002, IPR000832): 7 transmembrane receptor (Secretin family)
EGF (PF00008, IPR000742, SM00181): EGF-like domain
EGF_2 (PF07974, IPR013111): EGF-like domain
GPS (PF01825, IPR000203, SM00303): GPCR proteolysis site, GPS, motif
Laminin_G_2 (PF02210, IPR001791): Laminin G domain
Cadherin (PF00028, IPR002126, SM00112): Cadherin domain
Laminin_EGF (PF00053, IPR002049, SM00180): Laminin EGF domain
hEGF (PF12661, IPR013032): Human growth factor-like EGF
Cadherin_3 (PF16184): Cadherin-like
GAIN (PF16489, IPR032471): GPCR-Autoproteolysis INducing (GAIN) domain
17 CHUKsuppressor220.41469.264Pkinase (PF00069, IPR000719): Protein kinase domain
IKKbetaNEMObind (PF12179, IPR022007): I-kappa-kinase-beta NEMO binding domain
18 CLUsuppressor60.8000.582Clusterin (PF01093, IPR000753): Clusterin
19 CPDinteractor21.0000Peptidase_M14 (PF00246, IPR000834, SM00631): Zinc carboxypeptidase
CarboxypepD_reg (PF13620): Carboxypeptidase regulatory-like domain
20 CYLDsuppressor110.6735.988CAP_GLY (PF01302, IPR000938, SM01052): CAP-Gly domain
UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase
zf-HIT (PF04438, IPR007529): HIT zinc finger
CYLD_phos_site (PF16607): Phosphorylation region of CYLD, unstructured
21 DAG1interactor40.6671.167DAG1 (PF05454, IPR008465): Dystroglycan (Dystrophin-associated glycoprotein 1)
22 DCNsuppressor100LRRNT (PF01462, IPR000372, SM00013): Leucine rich repeat N-terminal domain
LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies)
LRR_8 (PF13855, IPR001611): Leucine rich repeat
23 DDX19Binteractor30.6670.667DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
24 ELAVL1oncoprotein220.190148.510RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
25 FADDsuppressor100.7335.072Death (PF00531, IPR000488, SM00005): Death domain
DED (PF01335, IPR001875, SM00031): Death effector domain
Hpt (PF01627, IPR008207, SM00073): Hpt domain
26 FASsuppressor110.51118.300Death (PF00531, IPR000488, SM00005): Death domain
TNFR_c6 (PF00020, IPR001368, SM00208): TNFR/NGFR cysteine-rich region
Stn1_C (PF12659, IPR024263): Telomere capping C-terminal wHTH
27 FBXW11interactor70.7331.586WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Beta-TrCP_D (PF12125, IPR021977, SM01028): D domain of beta-TrCP
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
F-box-like (PF12937, IPR001810): F-box-like
28 FLT4interactor21.0000I-set (PF07679, IPR013098): Immunoglobulin I-set domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
V-set (PF07686, IPR013106): Immunoglobulin V-set domain
Ig_2 (PF13895, IPR007110): Immunoglobulin domain
Ig_3 (PF13927): Immunoglobulin domain
Izumo-Ig (PF16706, IPR032699): Izumo-like Immunoglobulin domain
29 FREM2interactor100Calx-beta (PF03160, IPR003644, SM00237): Calx-beta domain
Cadherin_3 (PF16184): Cadherin-like
30 FYNoncoprotein70.6673.067Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
SH2 (PF00017, IPR000980, SM00252): SH2 domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
31 GKinteractor100FGGY_C (PF02782, IPR018485): FGGY family of carbohydrate kinases, C-terminal domain
FGGY_N (PF00370, IPR018484): FGGY family of carbohydrate kinases, N-terminal domain
32 GLSinteractor100Glutaminase (PF04960, IPR015868): Glutaminase
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
33 GUF1interactor100EFG_C (PF00679, IPR000640, SM00838): Elongation factor G C-terminus
GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain
GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2
LepA_C (PF06421, IPR013842): GTP-binding protein LepA C-terminus
SRPRB (PF09439, IPR019009): Signal recognition particle receptor beta subunit
RF3_C (PF16658, IPR032090): Class II release factor RF3, C-terminal domain
34 HNRNPA1interactor110.44416.333RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
HnRNPA1 (PF11627, IPR021662): Nuclear factor hnRNPA1
35 HNRNPDoncoprotein90.39313.286CBFNT (PF08143, IPR012956): CBFNT (NUC161) domain
NID (PF07292, IPR009909): Nmi/IFP 35 domain (NID)
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
Keratin_2_head (PF16208, IPR032444): Keratin type II head
36 HS6ST2interactor100Sulfotransfer_2 (PF03567, IPR005331): Sulfotransferase family
Clr2 (PF10383, IPR018839): Transcription-silencing protein Clr2
37 HSP90B3Pinteractor100NA
38 HSPA12Ainteractor100HSP70 (PF00012, IPR013126): Hsp70 protein
39 HSPA13interactor100HSP70 (PF00012, IPR013126): Hsp70 protein
40 HSPB1oncoprotein120.43616.373HSP20 (PF00011, IPR002068): Hsp20/alpha crystallin family
41 HSPB2interactor50.5002.667Crystallin (PF00525, IPR003090): Alpha crystallin A chain, N terminal
HSP20 (PF00011, IPR002068): Hsp20/alpha crystallin family
42 ICOSinteractor200V-set_2 (PF15910, IPR013106): ICOS V-set domain
43 IKBKBprotein found in more fusions160.58116.787FliT (PF05400, IPR008622): Flagellar protein FliT
Glyco_hydro_65m (PF03632, IPR005195): Glycosyl hydrolase family 65 central catalytic domain
Pkinase (PF00069, IPR000719): Protein kinase domain
SlyX (PF04102, IPR007236): SlyX
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
IKKbetaNEMObind (PF12179, IPR022007): I-kappa-kinase-beta NEMO binding domain
44 IKBKGinteractor270.345139.549CENP-H (PF05837, IPR008426): Centromere protein H (CENP-H)
DUF725 (PF05267, IPR007931): Protein of unknown function (DUF725)
NEMO (PF11577, IPR021063): NF-kappa-B essential modulator NEMO
LLC1 (PF14945, IPR020339): Normal lung function maintenance, Low in Lung Cancer 1 protein
CC2-LZ (PF16516, IPR032419): Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator
45 INTS5interactor100INTS5_N (PF14837, IPR029445): Integrator complex subunit 5 N-terminus
INTS5_C (PF14838, IPR029444): Integrator complex subunit 5 C-terminus
46 ITIH2interactor100ITI_HC_C (PF06668, IPR010600): Inter-alpha-trypsin inhibitor heavy chain C-terminus
VIT (PF08487, IPR013694, SM00609): Vault protein inter-alpha-trypsin domain
VWA (PF00092, IPR002035, SM00327): von Willebrand factor type A domain
DUF4561 (PF15120, IPR027818): Domain of unknown function (DUF4561)
47 LAMP2protein found in more fusions41.0000Lamp (PF01299, IPR002000): Lysosome-associated membrane glycoprotein (Lamp)
48 LNPEPoncoprotein100Peptidase_M1 (PF01433, IPR014782): Peptidase family M1
ERAP1_C (PF11838, IPR024571): ERAP1-like C-terminal domain
Dynactin (PF12455, IPR022157): Dynein associated protein
49 LYNoncoprotein50.6671.286Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
SH2 (PF00017, IPR000980, SM00252): SH2 domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
50 MAP2K2interactor200Pkinase (PF00069, IPR000719): Protein kinase domain
CAMSAP_CC1 (PF17095, IPR031372): Spectrin-binding region of Ca2+-Calmodulin
51 MAP3K7oncoprotein140.61511.177Mnd1 (PF03962, IPR005647): Mnd1 family
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
52 MTX3interactor100Tom37 (PF10568, IPR019564): Outer mitochondrial membrane transport complex protein
GST_C_6 (PF17171): Glutathione S-transferase, C-terminal domain
53 NCLNinteractor100Peptidase_M28 (PF04389, IPR007484): Peptidase family M28
54 NCR3LG1interactor100Gag_MA (PF01140, IPR000840): Matrix protein (MA), p15
V-set (PF07686, IPR013106): Immunoglobulin V-set domain
C1-set (PF07654, IPR003597, SM00407): Immunoglobulin C1-set domain
55 NEK7interactor100Pkinase (PF00069, IPR000719): Protein kinase domain
56 NEO1interactor21.0000fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
I-set (PF07679, IPR013098): Immunoglobulin I-set domain
Neogenin_C (PF06583, IPR010560): Neogenin C-terminus
V-set (PF07686, IPR013106): Immunoglobulin V-set domain
Ig_2 (PF13895, IPR007110): Immunoglobulin domain
Ig_3 (PF13927): Immunoglobulin domain
EphA2_TM (PF14575, IPR027936): Ephrin type-A receptor 2 transmembrane domain
57 NFKBIAoncoprotein110.49115.386Ank (PF00023, IPR002110, SM00248): Ankyrin repeat
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
Ank_4 (PF13637): Ankyrin repeats (many copies)
Ank_5 (PF13857): Ankyrin repeats (many copies)
58 NRP1interactor21.0000CUB (PF00431, IPR000859, SM00042): CUB domain
MAM (PF00629, IPR000998, SM00137): MAM domain, meprin/A5/mu
F5_F8_type_C (PF00754, IPR000421, SM00231): F5/8 type C domain
DUF3481 (PF11980, IPR022579): C-terminal domain of neuropilin glycoprotein
59 OPTNprotein found in more fusions110.46713.123ARD (PF03079, IPR004313): ARD/ARD' family
bZIP_1 (PF00170, IPR004827): bZIP transcription factor
HALZ (PF02183, IPR003106, SM00340): Homeobox associated leucine zipper
Uso1_p115_C (PF04871, IPR006955): Uso1 / p115 like vesicle tethering protein, C terminal region
NEMO (PF11577, IPR021063): NF-kappa-B essential modulator NEMO
CC2-LZ (PF16516, IPR032419): Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator
60 OTULINinteractor60.6671.836Peptidase_C101 (PF16218, IPR023235): Peptidase family C101
61 PCDH7interactor100Cadherin_2 (PF08266, IPR013164): Cadherin-like
Protocadherin (PF08374, IPR013585): Protocadherin
Cadherin (PF00028, IPR002126, SM00112): Cadherin domain
SelK_SelG (PF10961, IPR024491): Selenoprotein SelK_SelG
Cadherin_3 (PF16184): Cadherin-like
62 PLXNA2interactor100IncA (PF04156, IPR007285): IncA protein
Plexin_cytopl (PF08337, IPR013548): Plexin cytoplasmic RasGAP domain
PSI (PF01437, IPR002165, SM00423): Plexin repeat
Sema (PF01403, IPR001627, SM00630): Sema domain
TIG (PF01833, IPR002909): IPT/TIG domain
63 POU2F1protein found in more fusions200Pou (PF00157, IPR000327, SM00352): Pou domain - N-terminal to homeobox domain
Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
DUF3597 (PF12200, IPR022016): Domain of unknown function (DUF3597)
64 PSMD9interactor41.0000Remorin_C (PF03763, IPR005516): Remorin, C-terminal region
DUF2046 (PF09755, IPR019152): Uncharacterized conserved protein H4 (DUF2046)
PDZ_2 (PF13180, IPR001478): PDZ domain
65 PTPRSinteractor100fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
I-set (PF07679, IPR013098): Immunoglobulin I-set domain
Y_phosphatase (PF00102, IPR000242, SM00194): Protein-tyrosine phosphatase
Ig_3 (PF13927): Immunoglobulin domain
66 RAB18oncoprotein100Ras (PF00071, IPR001806, SM00173): Ras family
67 RAB5Aoncoprotein40.6671.667Ras (PF00071, IPR001806, SM00173): Ras family
68 RAC1oncoprotein60.5002.567Ras (PF00071, IPR001806, SM00173): Ras family
69 RALBP1interactor60.5333.082DDHD (PF02862, IPR004177, SM01127): DDHD domain
RhoGAP (PF00620, IPR000198, SM00324): RhoGAP domain
SlyX (PF04102, IPR007236): SlyX
Vps39_2 (PF10367, IPR019453): Vacuolar sorting protein 39 domain 2
DUF2968 (PF11180, IPR021350): Protein of unknown function (DUF2968)
DUF3505 (PF12013, IPR022698): Protein of unknown function (DUF3505)
Nod1 (PF17114, IPR032634): Gef2-related medial cortical node protein Nod1
70 RBCK1interactor120.6367.748GAGA (PF09237, IPR015318): GAGA factor
IBR (PF01485, IPR002867, SM00647): IBR domain, a half RING-finger domain
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others
zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger
71 RC3H1interactor21.0000PaaA_PaaC (PF05138, IPR007814): Phenylacetic acid catabolic protein
zf-CCCH (PF00642, IPR000571): Zinc finger C-x8-C-x5-C-x3-H type (and similar)
zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger
Prok-RING_4 (PF14447): Prokaryotic RING finger family 4
72 RHEBoncoprotein21.0000Ras (PF00071, IPR001806, SM00173): Ras family
73 RIPK1protein found in more fusions220.50542.774Death (PF00531, IPR000488, SM00005): Death domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
RHIM (PF12721, IPR025735): RIP homotypic interaction motif
74 RNF31interactor130.7276.375Auto_anti-p27 (PF06677, IPR009563): Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27)
IBR (PF01485, IPR002867, SM00647): IBR domain, a half RING-finger domain
PUB (PF09409, IPR018997): PUB domain
TF_Zn_Ribbon (PF08271, IPR013137): TFIIB zinc-binding
zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger
zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others
zf-RING_4 (PF14570): RING/Ubox like zinc-binding domain
HOIP-UBA (PF16678, IPR032065): UB-associated-like domain of HOIP or E3 ubiquitin-protein ligase
75 RNF8suppressor50.6670.468FHA (PF00498, IPR000253, SM00240): FHA domain
Jnk-SapK_ap_N (PF09744, IPR019143): JNK_SAPK-associated protein-1
zf-C2H2_2 (PF12756, IPR015880): C2H2 type zinc-finger (2 copies)
zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
DUF4665 (PF15679, IPR031389): Domain of unknown function (DUF4665)
76 SEC61A1interactor21.0000DUF1430 (PF07242, IPR006541): Protein of unknown function (DUF1430)
SecY (PF00344, IPR002208): SecY translocase
Plug_translocon (PF10559, IPR019561): Plug domain of Sec61p
77 SEMA4Cinteractor100DUF1049 (PF06305, IPR010445): Protein of unknown function (DUF1049)
PSI (PF01437, IPR002165, SM00423): Plexin repeat
Sema (PF01403, IPR001627, SM00630): Sema domain
Ig_2 (PF13895, IPR007110): Immunoglobulin domain
78 SFXN5interactor21.0000Mtc (PF03820, IPR004686): Tricarboxylate carrier
79 SHARPINinteractor110.6675.872DUF1518 (PF07469, IPR010011, SM01151): Domain of unknown function (DUF1518)
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others
Sharpin_PH (PF16764, IPR031912): Sharpin PH domain
80 TAB1interactor70.8570.983PP2C (PF00481, IPR001932): Protein phosphatase 2C
81 TAB2oncoprotein110.7783.031CUE (PF02845, IPR003892, SM00546): CUE domain
DivIC (PF04977, IPR007060): Septum formation initiator
Mnd1 (PF03962, IPR005647): Mnd1 family
zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others
82 TAMM41interactor200Mmp37 (PF09139, IPR015222): Mitochondrial matrix Mmp37
83 TBK1interactor110.48910.837DUF713 (PF05218, IPR007883): Protein of unknown function (DUF713)
NPV_P10 (PF05531, IPR008702): Nucleopolyhedrovirus P10 protein
Pkinase (PF00069, IPR000719): Protein kinase domain
84 TM2D3interactor100TM2 (PF05154, IPR007829): TM2 domain
85 TMEM259interactor100Membralin (PF09746, IPR019144): Tumour-associated protein
86 TNFAIP3suppressor200.48541.441OTU (PF02338, IPR003323): OTU-like cysteine protease
zf-A20 (PF01754, IPR002653, SM00259): A20-like zinc finger
Thioredoxin_3 (PF13192, IPR012336): Thioredoxin domain
87 TNFRSF1Aoncoprotein240.39186.845Death (PF00531, IPR000488, SM00005): Death domain
TNFR_c6 (PF00020, IPR001368, SM00208): TNFR/NGFR cysteine-rich region
88 TNFRSF1Boncoprotein80.9050.733TNFR_c6 (PF00020, IPR001368, SM00208): TNFR/NGFR cysteine-rich region
89 TNFSF9suppressor100Albumin_I (PF08027, IPR012512): Albumin I chain b
TNF (PF00229, IPR006052, SM00207): TNF(Tumour Necrosis Factor) family
90 TNIP1interactor80.6673.027ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16)
DUF724 (PF05266, IPR007930): Protein of unknown function (DUF724)
Filament (PF00038, IPR001664): Intermediate filament protein
HALZ (PF02183, IPR003106, SM00340): Homeobox associated leucine zipper
TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein
DUF4201 (PF13870, IPR025254): Domain of unknown function (DUF4201)
FlxA (PF14282, IPR025577): FlxA-like protein
CC2-LZ (PF16516, IPR032419): Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator
91 TRADDinteractor120.6916.855Death (PF00531, IPR000488, SM00005): Death domain
TRADD_N (PF09034, IPR009095): TRADD, N-terminal domain
TPR_14 (PF13428): Tetratricopeptide repeat
92 TRAF2interactor280.333152.745MATH (PF00917, IPR002083, SM00061): MATH domain
Sina (PF03145, IPR018121): Seven in absentia protein family
SlyX (PF04102, IPR007236): SlyX
zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger)
zf-TRAF (PF02176, IPR001293): TRAF-type zinc finger
TRAF_BIRC3_bd (PF16673, IPR032070): TNF receptor-associated factor BIRC3 binding domain
zf-C3HC4_5 (PF17121, IPR001841): Zinc finger, C3HC4 type (RING finger)
93 UBCprotein found in more fusions250.272142.400ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
94 UBE2Nprotein found in more fusions120.50916.756UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
95 UFL1suppressor100CBFD_NFYB_HMF (PF00808, IPR003958): Histone-like transcription factor (CBF/NF-Y) and archaeal histone
Helicase_RecD (PF05127, IPR007807): Helicase
DUF2042 (PF09743, IPR018611): Uncharacterized conserved protein (DUF2042)
UBN_AB (PF14075, IPR026947): Ubinuclein conserved middle domain
IL31 (PF15209, IPR027987): Interleukin 31
96 YWHAQinteractor70.38110.45214-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
97 ZFP36suppressor30.6670.667zf-CCCH (PF00642, IPR000571): Zinc finger C-x8-C-x5-C-x3-H type (and similar)

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