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Visible interactions: all affected independent (normal) missing (in fusions) nothing (blank)

Visualization interactions

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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)62
The number (and %) of the onco-proteins13 (20.97 %)
The number (and %) of the tumor suppressors6 (9.68 %)
Total number of binary PPIs (saturation %)187 (9.89 %)
The number (and %) of affected PPIs62 (33.16 %)
The number of possible different fusions6
PPI diameter2
PPI radius1
The average degree of PPI5.387
Assortativity coefficient-0.4156
The network average Clustering coefficient0.598
The number (and %) of a zero Clustering coefficients11 (17.74 %)
The number (and %) of a zero Betweenness Centrality28 (45.16 %)

ACTIVE INTERACTORS
MISSING INTERACTORS (in fusions)


List of the fusions

PPI for parental proteins: THAP7 All fusions
: AA426248;
Proteins found in more fusions APP (see 4 fusions); TRIM26 (see 1 fusions); HCFC1 (see 2 fusions); ZDHHC17 (see 2 fusions); THAP7 (see 1 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 THAP7parental protein620.0583164.500THAP (PF05485, IPR006612, SM00980): THAP domain
Tho2 (PF11262, IPR021418): Transcription factor/nuclear export subunit protein 2
2 APPprotein found in more fusions100.22226.167APP_N (PF02177, IPR015849, SM00006): Amyloid A4 N-terminal heparin-binding
Beta-APP (PF03494, IPR013803): Beta-amyloid peptide (beta-APP)
BUD22 (PF09073, IPR015158): BUD22
IncA (PF04156, IPR007285): IncA protein
Kunitz_BPTI (PF00014, IPR002223, SM00131): Kunitz/Bovine pancreatic trypsin inhibitor domain
APP_amyloid (PF10515, IPR019543): beta-amyloid precursor protein C-terminus
APP_Cu_bd (PF12924, IPR011178): Copper-binding of amyloid precursor, CuBD
APP_E2 (PF12925, IPR024329): E2 domain of amyloid precursor protein
3 ASH1Linteractor21.0000AT_hook (PF02178, IPR017956, SM00384): AT hook motif
BAH (PF01426, IPR001025, SM00439): BAH domain
PHD (PF00628, IPR019787, SM00249): PHD-finger
SET (PF00856, IPR001214, SM00317): SET domain
Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
4 ASPMoncoprotein21.0000CcmD (PF04995, IPR007078): Heme exporter protein D (CcmD)
CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif
RST (PF12174, IPR022003): RCD1-SRO-TAF4 (RST) plant domain
ASH (PF15780, IPR031549): Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin
5 C7orf50interactor40.5002.167DUF2373 (PF10180, IPR019327): Uncharacterised conserved protein (DUF2373)
6 CCDC85Binteractor40.5002.333CCDC85 (PF10226, IPR019359): CCDC85 family
7 CCNDBP1suppressor100CheF-arch (PF04283, IPR007381): Chemotaxis signal transduction system protein F from archaea
GCIP (PF13324): Grap2 and cyclin-D-interacting
8 CEBPZinteractor60.8670.800BRF1 (PF07741, IPR011665): Brf1-like TBP-binding domain
CBF (PF03914, IPR005612, SM00521): CBF/Mak21 family
Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1
9 DDX24interactor80.6437.700DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
OAD_gamma (PF04277, IPR005899): Oxaloacetate decarboxylase, gamma chain
Sec62 (PF03839, IPR004728): Translocation protein Sec62
Tti2 (PF10521, IPR018870): Tti2 family
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
10 EBNA1BP2interactor90.6676.467Ebp2 (PF05890, IPR008610): Eukaryotic rRNA processing protein EBP2
11 EHMT2interactor40.6671.000CDC45 (PF02724, IPR003874): CDC45-like protein
Pre-SET (PF05033, IPR007728): Pre-SET motif
Ribosomal_L32p (PF01783, IPR002677): Ribosomal L32p protein family
SET (PF00856, IPR001214, SM00317): SET domain
SMN (PF06003, IPR010304): Survival motor neuron protein (SMN)
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
CSRNP_N (PF16019, IPR031972): Cysteine/serine-rich nuclear protein N-terminus
12 EXOC1interactor100FlaC_arch (PF05377, IPR008039): Flagella accessory protein C (FlaC)
Sec3_C (PF09763, IPR019160): Exocyst complex component Sec3
Sec3-PIP2_bind (PF15277, IPR028258): Exocyst complex component SEC3 N-terminal PIP2 binding PH
13 FBXO11oncoprotein100TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
zf-UBR (PF02207, IPR003126): Putative zinc finger in N-recognin (UBR box)
F-box-like (PF12937, IPR001810): F-box-like
Beta_helix (PF13229): Right handed beta helix region
14 GNAI1oncoprotein100G-alpha (PF00503, IPR001019, SM00275): G-protein alpha subunit
15 GOLGA2interactor40.5003.000ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16)
Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein
Rootletin (PF15035): Ciliary rootlet component, centrosome cohesion
GOLGA2L5 (PF15070, IPR024858): Putative golgin subfamily A member 2-like protein 5
16 HCFC1protein found in more fusions200fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
Kelch_1 (PF01344, IPR006652, SM00612): Kelch motif
Kelch_3 (PF13415): Galactose oxidase, central domain
Kelch_5 (PF13854): Kelch motif
zf-tcix (PF14952, IPR029269): Putative treble-clef, zinc-finger, Zn-binding
17 HDAC3suppressor60.7003.000Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
18 HINFPinteractor21.0000SLIDE (PF09111, IPR015195): SLIDE
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-C2H2_2 (PF12756, IPR015880): C2H2 type zinc-finger (2 copies)
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger
FOXP-CC (PF16159, IPR032354): FOXP coiled-coil domain
zf-C2HE (PF16278, IPR032566): C2HE / C2H2 / C2HC zinc-binding finger
19 HIST1H2AGinteractor21.0000Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
Histone_H2A_C (PF16211, IPR032454): C-terminus of histone H2A
20 HIST1H3Ainteractor110.28931.000Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
21 HIST1H4Ainteractor50.8001.333CENP-T_C (PF15511): Centromere kinetochore component CENP-T histone fold
22 KRT31interactor21.0000Filament (PF00038, IPR001664): Intermediate filament protein
23 KRT40interactor21.0000Filament (PF00038, IPR001664): Intermediate filament protein
UPF0184 (PF03670, IPR022788): Uncharacterised protein family (UPF0184)
24 KRTAP10-3interactor60.7003.000Keratin_B2 (PF01500, IPR002494): Keratin, high sulfur B2 protein
Keratin_B2_2 (PF13885, IPR002494): Keratin, high sulfur B2 protein
25 KRTAP10-8interactor51.0000Keratin_B2 (PF01500, IPR002494): Keratin, high sulfur B2 protein
PMG (PF05287, IPR007951): PMG protein
Keratin_B2_2 (PF13885, IPR002494): Keratin, high sulfur B2 protein
26 KRTAP4-12interactor60.8001.333Keratin_B2_2 (PF13885, IPR002494): Keratin, high sulfur B2 protein
27 LNX1interactor90.28619.000PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
zf-rbx1 (PF12678, IPR024766): RING-H2 zinc finger domain
zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
28 LURAP1interactor100LURAP (PF14854): Leucine rich adaptor protein
DUF4530 (PF15039, IPR029202): Domain of unknown function (DUF4530)
29 LZTS2suppressor40.5002.667CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
DUF1127 (PF06568, IPR009506): Domain of unknown function (DUF1127)
Fez1 (PF06818): Fez1
ADIP (PF11559, IPR021622): Afadin- and alpha -actinin-Binding
DUF4250 (PF14056, IPR025346): Domain of unknown function (DUF4250)
30 MAP1LC3Binteractor100Atg8 (PF02991, IPR004241): Autophagy protein Atg8 ubiquitin like
31 MDFIinteractor31.0000MDFI (PF15316, IPR026134): MyoD family inhibitor
32 MID2interactor40.6671.000fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
SPRY (PF00622, IPR003877, SM00449): SPRY domain
zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger
PRY (PF13765, IPR006574, SM00589): SPRY-associated domain
zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger
CEBP_ZZ (PF16366, IPR032296): Cytoplasmic polyadenylation element-binding protein ZZ domain
APC_u15 (PF16636): Unstructured region on APC between APC_crr regions 5 and 6
33 MTUS2suppressor40.6670.667DUF496 (PF04363, IPR007458): Protein of unknown function (DUF496)
RNA_pol_Rpb1_R (PF05001, IPR000684): RNA polymerase Rpb1 C-terminal repeat
FAM184 (PF15665): Family with sequence similarity 184, A and B
34 NCOR1oncoprotein41.0000BES1_N (PF05687, IPR008540): BES1/BZR1 plant transcription factor, N-terminal
Lamp (PF01299, IPR002000): Lysosome-associated membrane glycoprotein (Lamp)
MAS20 (PF02064, IPR002056): MAS20 protein import receptor
Neur_chan_memb (PF02932, IPR006029): Neurotransmitter-gated ion-channel transmembrane region
Eapp_C (PF10238, IPR019370): E2F-associated phosphoprotein
Hid1 (PF12722): High-temperature-induced dauer-formation protein
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
DUF3915 (PF13054, IPR025026): Protein of unknown function (DUF3915)
GPS2_interact (PF15784, IPR031557): G-protein pathway suppressor 2-interacting domain
DUF4834 (PF16118, IPR032272): Domain of unknown function (DUF4834)
RBR (PF17208): RNA binding Region
35 NIP7interactor70.6674.333UPF0113 (PF03657, IPR005155): Uncharacterised protein family (UPF0113)
36 NLE1oncoprotein100NLE (PF08154, IPR012972): NLE (NUC135) domain
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
37 NOP2interactor90.6945.433BSP_II (PF05432, IPR008412): Bone sialoprotein II (BSP-II)
Methyltr_RsmB-F (PF01189, IPR001678): 16S rRNA methyltransferase RsmB/F
P120R (PF08062, IPR012586): P120R (NUC006) repeat
Prefoldin_2 (PF01920, IPR002777): Prefoldin subunit
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
DUF2477 (PF10631, IPR018904): Protein of unknown function (DUF2477)
FAM176 (PF14851): FAM176 family
Methyltr_RsmF_N (PF17125, IPR031341): N-terminal domain of 16S rRNA methyltransferase RsmF
38 NOP56interactor160.41752.000Cytochrom_NNT (PF03264, IPR005126): NapC/NirT cytochrome c family, N-terminal region
Nop (PF01798, IPR002687): snoRNA binding domain, fibrillarin
NOP5NT (PF08156, IPR012974): NOP5NT (NUC127) domain
RNA_polI_A34 (PF08208, IPR013240): DNA-directed RNA polymerase I subunit RPA34.5
SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal
39 NOTCH2NLinteractor50.8001.333EGF (PF00008, IPR000742, SM00181): EGF-like domain
EGF_alliinase (PF04863, IPR006947): Alliinase EGF-like domain
EGF_CA (PF07645, IPR001881, SM00179): Calcium-binding EGF domain
cEGF (PF12662, IPR026823): Complement Clr-like EGF-like
40 PELI2interactor100Pellino (PF04710, IPR006800): Pellino
41 PHC2interactor31.0000SAM_1 (PF00536, IPR021129, SM00454): SAM domain (Sterile alpha motif)
TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
zf-CGNR (PF11706, IPR021005): CGNR zinc finger
DUF4692 (PF15763, IPR031517): Domain of unknown function (DUF4692)
PHC2_SAM_assoc (PF16616): Unstructured region on Polyhomeotic-like protein 1 and 2
42 PIN1suppressor110.20043.667Rotamase (PF00639, IPR000297): PPIC-type PPIASE domain
WW (PF00397, IPR001202, SM00456): WW domain
43 PPP3CCsuppressor21.0000Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase
PTEN_C2 (PF10409, IPR014020): C2 domain of PTEN tumour-suppressor protein
44 PUM3interactor70.7144.500CPL (PF08144, IPR012959): CPL (NUC119) domain
45 RBM34oncoprotein50.7002.167RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
DUF3139 (PF11337, IPR021486): Protein of unknown function (DUF3139)
46 RPL13interactor100.55614.733Ribosomal_L13e (PF01294, IPR001380): Ribosomal protein L13e
47 RPL13Ainteractor70.9520.333Ribosomal_L13 (PF00572, IPR005822): Ribosomal protein L13
48 RPL18Ainteractor90.6946.567Ribosomal_L18A (PF01775, IPR023573): Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A
49 RPL26oncoprotein41.0000TP2 (PF01254, IPR000678): Nuclear transition protein 2
Ribosomal_L26 (PF16906, IPR005756): Ribosomal proteins L26 eukaryotic, L24P archaeal
50 RPL26L1interactor21.0000Ribosomal_L26 (PF16906, IPR005756): Ribosomal proteins L26 eukaryotic, L24P archaeal
51 RPL32interactor61.0000Ribosomal_L32e (PF01655, IPR001515): Ribosomal protein L32
52 RPL7interactor110.58216.300Ribosomal_L30 (PF00327, IPR016082): Ribosomal protein L30p/L7e
Ribosomal_L30_N (PF08079, IPR012988): Ribosomal L30 N-terminal domain
53 RPS27Ainteractor40.6672.000DUF1049 (PF06305, IPR010445): Protein of unknown function (DUF1049)
54 RPS3Ainteractor90.6946.833Ribosomal_S3Ae (PF01015, IPR001593): Ribosomal S3Ae family
55 SEToncoprotein40.6670.667NAP (PF00956, IPR002164): Nucleosome assembly protein (NAP)
Nop14 (PF04147, IPR007276): Nop14-like family
DUF2457 (PF10446, IPR018853): Protein of unknown function (DUF2457)
56 TAF1Binteractor40.6671.667Cytochrom_NNT (PF03264, IPR005126): NapC/NirT cytochrome c family, N-terminal region
zf-RRN7 (PF11781, IPR021752): Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7
57 TFIP11interactor100G-patch (PF01585, IPR000467, SM00443): G-patch domain
GCFC (PF07842, IPR022783): GC-rich sequence DNA-binding factor-like protein
TIP_N (PF12457, IPR022159): Tuftelin interacting protein N terminal
58 TRAF1oncoprotein41.0000HypA (PF01155, IPR000688): Hydrogenase/urease nickel incorporation, metallochaperone, hypA
SlyX (PF04102, IPR007236): SlyX
TRAF_BIRC3_bd (PF16673, IPR032070): TNF receptor-associated factor BIRC3 binding domain
59 TRAF2interactor70.4008.333MATH (PF00917, IPR002083, SM00061): MATH domain
Sina (PF03145, IPR018121): Seven in absentia protein family
SlyX (PF04102, IPR007236): SlyX
zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger)
zf-TRAF (PF02176, IPR001293): TRAF-type zinc finger
TRAF_BIRC3_bd (PF16673, IPR032070): TNF receptor-associated factor BIRC3 binding domain
zf-C3HC4_5 (PF17121, IPR001841): Zinc finger, C3HC4 type (RING finger)
60 TRIM26protein found in more fusions200Nop14 (PF04147, IPR007276): Nop14-like family
SPRY (PF00622, IPR003877, SM00449): SPRY domain
IFT57 (PF10498, IPR019530): Intra-flagellar transport protein 57
zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger
PRY (PF13765, IPR006574, SM00589): SPRY-associated domain
zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger
zf-C3HC4_4 (PF15227): zinc finger of C3HC4-type, RING
61 ZDHHC17protein found in more fusions31.0000zf-DHHC (PF01529, IPR001594): DHHC palmitoyltransferase
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
Ank_3 (PF13606, IPR002110): Ankyrin repeat
Ank_4 (PF13637): Ankyrin repeats (many copies)
62 ZNF512interactor21.0000IBR (PF01485, IPR002867, SM00647): IBR domain, a half RING-finger domain
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-C2H2_jaz (PF12171, IPR022755): Zinc-finger double-stranded RNA-binding
CpXC (PF14353, IPR025682): CpXC protein
zf-C2H2_aberr (PF17017, IPR031514): Aberrant zinc-finger

B a c k    t o    T o p ⇑


List of missing interactors (in fusions)

# Name Type Domains (Pfam, InterPro, SMART): description Fusion(s)
1 ASH1LinteractorAT_hook (PF02178, IPR017956, SM00384): AT hook motif
BAH (PF01426, IPR001025, SM00439): BAH domain
PHD (PF00628, IPR019787, SM00249): PHD-finger
SET (PF00856, IPR001214, SM00317): SET domain
Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
AA426248
2 ASPMoncoproteinCcmD (PF04995, IPR007078): Heme exporter protein D (CcmD)
CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif
RST (PF12174, IPR022003): RCD1-SRO-TAF4 (RST) plant domain
ASH (PF15780, IPR031549): Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin
AA426248
3 C7orf50interactorDUF2373 (PF10180, IPR019327): Uncharacterised conserved protein (DUF2373)AA426248
4 CCDC85BinteractorCCDC85 (PF10226, IPR019359): CCDC85 familyAA426248
5 CCNDBP1suppressorCheF-arch (PF04283, IPR007381): Chemotaxis signal transduction system protein F from archaea
GCIP (PF13324): Grap2 and cyclin-D-interacting
AA426248
6 CEBPZinteractorBRF1 (PF07741, IPR011665): Brf1-like TBP-binding domain
CBF (PF03914, IPR005612, SM00521): CBF/Mak21 family
Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1
AA426248
7 DDX24interactorDEAD (PF00270, IPR011545): DEAD/DEAH box helicase
OAD_gamma (PF04277, IPR005899): Oxaloacetate decarboxylase, gamma chain
Sec62 (PF03839, IPR004728): Translocation protein Sec62
Tti2 (PF10521, IPR018870): Tti2 family
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
AA426248
8 EBNA1BP2interactorEbp2 (PF05890, IPR008610): Eukaryotic rRNA processing protein EBP2AA426248
9 EXOC1interactorFlaC_arch (PF05377, IPR008039): Flagella accessory protein C (FlaC)
Sec3_C (PF09763, IPR019160): Exocyst complex component Sec3
Sec3-PIP2_bind (PF15277, IPR028258): Exocyst complex component SEC3 N-terminal PIP2 binding PH
AA426248
10 FBXO11oncoproteinTFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
zf-UBR (PF02207, IPR003126): Putative zinc finger in N-recognin (UBR box)
F-box-like (PF12937, IPR001810): F-box-like
Beta_helix (PF13229): Right handed beta helix region
AA426248
11 GNAI1oncoproteinG-alpha (PF00503, IPR001019, SM00275): G-protein alpha subunitAA426248
12 GOLGA2interactorATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16)
Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein
Rootletin (PF15035): Ciliary rootlet component, centrosome cohesion
GOLGA2L5 (PF15070, IPR024858): Putative golgin subfamily A member 2-like protein 5
AA426248
13 HDAC3suppressorHist_deacetyl (PF00850, IPR023801): Histone deacetylase domainAA426248
14 HINFPinteractorSLIDE (PF09111, IPR015195): SLIDE
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-C2H2_2 (PF12756, IPR015880): C2H2 type zinc-finger (2 copies)
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger
FOXP-CC (PF16159, IPR032354): FOXP coiled-coil domain
zf-C2HE (PF16278, IPR032566): C2HE / C2H2 / C2HC zinc-binding finger
AA426248
15 HIST1H2AGinteractorHistone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
Histone_H2A_C (PF16211, IPR032454): C-terminus of histone H2A
AA426248
16 HIST1H3AinteractorHistone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4AA426248
17 HIST1H4AinteractorCENP-T_C (PF15511): Centromere kinetochore component CENP-T histone foldAA426248
18 KRT31interactorFilament (PF00038, IPR001664): Intermediate filament proteinAA426248
19 KRT40interactorFilament (PF00038, IPR001664): Intermediate filament protein
UPF0184 (PF03670, IPR022788): Uncharacterised protein family (UPF0184)
AA426248
20 KRTAP4-12interactorKeratin_B2_2 (PF13885, IPR002494): Keratin, high sulfur B2 proteinAA426248
21 LNX1interactorPDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
zf-rbx1 (PF12678, IPR024766): RING-H2 zinc finger domain
zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
AA426248
22 LURAP1interactorLURAP (PF14854): Leucine rich adaptor protein
DUF4530 (PF15039, IPR029202): Domain of unknown function (DUF4530)
AA426248
23 LZTS2suppressorCAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
DUF1127 (PF06568, IPR009506): Domain of unknown function (DUF1127)
Fez1 (PF06818): Fez1
ADIP (PF11559, IPR021622): Afadin- and alpha -actinin-Binding
DUF4250 (PF14056, IPR025346): Domain of unknown function (DUF4250)
AA426248
24 MAP1LC3BinteractorAtg8 (PF02991, IPR004241): Autophagy protein Atg8 ubiquitin likeAA426248
25 MDFIinteractorMDFI (PF15316, IPR026134): MyoD family inhibitorAA426248
26 MTUS2suppressorDUF496 (PF04363, IPR007458): Protein of unknown function (DUF496)
RNA_pol_Rpb1_R (PF05001, IPR000684): RNA polymerase Rpb1 C-terminal repeat
FAM184 (PF15665): Family with sequence similarity 184, A and B
AA426248
27 NCOR1oncoproteinBES1_N (PF05687, IPR008540): BES1/BZR1 plant transcription factor, N-terminal
Lamp (PF01299, IPR002000): Lysosome-associated membrane glycoprotein (Lamp)
MAS20 (PF02064, IPR002056): MAS20 protein import receptor
Neur_chan_memb (PF02932, IPR006029): Neurotransmitter-gated ion-channel transmembrane region
Eapp_C (PF10238, IPR019370): E2F-associated phosphoprotein
Hid1 (PF12722): High-temperature-induced dauer-formation protein
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
DUF3915 (PF13054, IPR025026): Protein of unknown function (DUF3915)
GPS2_interact (PF15784, IPR031557): G-protein pathway suppressor 2-interacting domain
DUF4834 (PF16118, IPR032272): Domain of unknown function (DUF4834)
RBR (PF17208): RNA binding Region
AA426248
28 NIP7interactorUPF0113 (PF03657, IPR005155): Uncharacterised protein family (UPF0113)AA426248
29 NLE1oncoproteinNLE (PF08154, IPR012972): NLE (NUC135) domain
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
AA426248
30 NOP2interactorBSP_II (PF05432, IPR008412): Bone sialoprotein II (BSP-II)
Methyltr_RsmB-F (PF01189, IPR001678): 16S rRNA methyltransferase RsmB/F
P120R (PF08062, IPR012586): P120R (NUC006) repeat
Prefoldin_2 (PF01920, IPR002777): Prefoldin subunit
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
DUF2477 (PF10631, IPR018904): Protein of unknown function (DUF2477)
FAM176 (PF14851): FAM176 family
Methyltr_RsmF_N (PF17125, IPR031341): N-terminal domain of 16S rRNA methyltransferase RsmF
AA426248
31 NOP56interactorCytochrom_NNT (PF03264, IPR005126): NapC/NirT cytochrome c family, N-terminal region
Nop (PF01798, IPR002687): snoRNA binding domain, fibrillarin
NOP5NT (PF08156, IPR012974): NOP5NT (NUC127) domain
RNA_polI_A34 (PF08208, IPR013240): DNA-directed RNA polymerase I subunit RPA34.5
SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal
AA426248
32 NOTCH2NLinteractorEGF (PF00008, IPR000742, SM00181): EGF-like domain
EGF_alliinase (PF04863, IPR006947): Alliinase EGF-like domain
EGF_CA (PF07645, IPR001881, SM00179): Calcium-binding EGF domain
cEGF (PF12662, IPR026823): Complement Clr-like EGF-like
AA426248
33 PELI2interactorPellino (PF04710, IPR006800): PellinoAA426248
34 PHC2interactorSAM_1 (PF00536, IPR021129, SM00454): SAM domain (Sterile alpha motif)
TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
zf-CGNR (PF11706, IPR021005): CGNR zinc finger
DUF4692 (PF15763, IPR031517): Domain of unknown function (DUF4692)
PHC2_SAM_assoc (PF16616): Unstructured region on Polyhomeotic-like protein 1 and 2
AA426248
35 PIN1suppressorRotamase (PF00639, IPR000297): PPIC-type PPIASE domain
WW (PF00397, IPR001202, SM00456): WW domain
AA426248
36 PPP3CCsuppressorMetallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase
PTEN_C2 (PF10409, IPR014020): C2 domain of PTEN tumour-suppressor protein
AA426248
37 PUM3interactorCPL (PF08144, IPR012959): CPL (NUC119) domainAA426248
38 RBM34oncoproteinRRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
DUF3139 (PF11337, IPR021486): Protein of unknown function (DUF3139)
AA426248
39 RPL13interactorRibosomal_L13e (PF01294, IPR001380): Ribosomal protein L13eAA426248
40 RPL13AinteractorRibosomal_L13 (PF00572, IPR005822): Ribosomal protein L13AA426248
41 RPL18AinteractorRibosomal_L18A (PF01775, IPR023573): Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18AAA426248
42 RPL26oncoproteinTP2 (PF01254, IPR000678): Nuclear transition protein 2
Ribosomal_L26 (PF16906, IPR005756): Ribosomal proteins L26 eukaryotic, L24P archaeal
AA426248
43 RPL26L1interactorRibosomal_L26 (PF16906, IPR005756): Ribosomal proteins L26 eukaryotic, L24P archaealAA426248
44 RPL32interactorRibosomal_L32e (PF01655, IPR001515): Ribosomal protein L32AA426248
45 RPL7interactorRibosomal_L30 (PF00327, IPR016082): Ribosomal protein L30p/L7e
Ribosomal_L30_N (PF08079, IPR012988): Ribosomal L30 N-terminal domain
AA426248
46 RPS27AinteractorDUF1049 (PF06305, IPR010445): Protein of unknown function (DUF1049)AA426248
47 RPS3AinteractorRibosomal_S3Ae (PF01015, IPR001593): Ribosomal S3Ae familyAA426248
48 SEToncoproteinNAP (PF00956, IPR002164): Nucleosome assembly protein (NAP)
Nop14 (PF04147, IPR007276): Nop14-like family
DUF2457 (PF10446, IPR018853): Protein of unknown function (DUF2457)
AA426248
49 TAF1BinteractorCytochrom_NNT (PF03264, IPR005126): NapC/NirT cytochrome c family, N-terminal region
zf-RRN7 (PF11781, IPR021752): Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7
AA426248
50 TFIP11interactorG-patch (PF01585, IPR000467, SM00443): G-patch domain
GCFC (PF07842, IPR022783): GC-rich sequence DNA-binding factor-like protein
TIP_N (PF12457, IPR022159): Tuftelin interacting protein N terminal
AA426248
51 THAP7parental proteinTHAP (PF05485, IPR006612, SM00980): THAP domain
Tho2 (PF11262, IPR021418): Transcription factor/nuclear export subunit protein 2
AA426248
52 TRAF1oncoproteinHypA (PF01155, IPR000688): Hydrogenase/urease nickel incorporation, metallochaperone, hypA
SlyX (PF04102, IPR007236): SlyX
TRAF_BIRC3_bd (PF16673, IPR032070): TNF receptor-associated factor BIRC3 binding domain
AA426248
53 TRAF2interactorMATH (PF00917, IPR002083, SM00061): MATH domain
Sina (PF03145, IPR018121): Seven in absentia protein family
SlyX (PF04102, IPR007236): SlyX
zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger)
zf-TRAF (PF02176, IPR001293): TRAF-type zinc finger
TRAF_BIRC3_bd (PF16673, IPR032070): TNF receptor-associated factor BIRC3 binding domain
zf-C3HC4_5 (PF17121, IPR001841): Zinc finger, C3HC4 type (RING finger)
AA426248
54 TRIM26interactorNop14 (PF04147, IPR007276): Nop14-like family
SPRY (PF00622, IPR003877, SM00449): SPRY domain
IFT57 (PF10498, IPR019530): Intra-flagellar transport protein 57
zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger
PRY (PF13765, IPR006574, SM00589): SPRY-associated domain
zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger
zf-C3HC4_4 (PF15227): zinc finger of C3HC4-type, RING
AA426248
55 ZDHHC17interactorzf-DHHC (PF01529, IPR001594): DHHC palmitoyltransferase
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
Ank_3 (PF13606, IPR002110): Ankyrin repeat
Ank_4 (PF13637): Ankyrin repeats (many copies)
AA426248
56 ZNF512interactorIBR (PF01485, IPR002867, SM00647): IBR domain, a half RING-finger domain
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-C2H2_jaz (PF12171, IPR022755): Zinc-finger double-stranded RNA-binding
CpXC (PF14353, IPR025682): CpXC protein
zf-C2H2_aberr (PF17017, IPR031514): Aberrant zinc-finger
AA426248

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