Find Fusion Network

Visualization interactions

Powered by Cytoscape Web for: parental proteins TCF3 (from a repository: Thu Nov 10 14:59:26 2016)

Examples AFF1 MLL ACTN4 + MLLAFF1 + MLLALK + MSNALK + TFGALK + TPM3ALK + TPM4ASXL2 + KAT6AATF1 + FUSBCR + ABL1BCR + FGFR1CCND1 + TACSTD2CD74 + ROS1CDK6 + MLLCOL1A1 + PDGFBCREB3L2 + PPARGCREB3L2 + FUSCREBBP + KAT6ADAZAP1 + MEF2DELL + MLLEPS15 + MLLERG + EWSR1ERG + FUSERG + TMPRSS2ETV5 + TMPRSS2ETV6 + ABL1ETV6 + NTRK3ETV6 + PAX5EWSR1 + FLI1EWSR1 + WT1FOXO1 + PAX3FOXP1 + PAX5FRYL + MLLGAS7 + MLLGMPS + MLLGOLGA5 + RETHOOK3 + RETHOXC13 + NUP98HOXD13 + NUP98MECOM + RUNX1MKL1 + RBM15MLL + MLLT1MLL + MLLT4MLL + MLLT10MLL + PICALMMLLT10 + PICALMNCOA1 + PAX3NIN + PDGFRBNPM1 + RARANRG1 + ODZ4NTRK1 + TFGNUMA1 + RARANUP98 + PHF23PAX5 + ZNF521PBX1 + TCF3RET + TRIM27ROS1 + SLC34A2PML + RARAPRKAR1A + RARAPRKAR1A + RETRUNX1 + RUNX1T1RUNX1 + SH3D19	Cytoscape Web will replace the contents your graph	PPI Properties: Click on nodes or edges
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Statistics and Network structure information

Statistic of PPI Value(s) The number of interactors (fusion and proteins) 134 The number (and %) of the onco-proteins 42 (31.34 %) The number (and %) of the tumor suppressors 5 (3.73 %) Total number of binary PPIs (saturation %) 466 (5.23 %) The number (and %) of affected PPIs 134 (28.76 %) The number of possible different fusions 26 PPI diameter 2 PPI radius 1 The average degree of PPI 6.299 Assortativity coefficient -0.3658 The network average Clustering coefficient 0.507 The number (and %) of a zero Clustering coefficients 29 (21.64 %) The number (and %) of a zero Betweenness Centrality 56 (41.79 %)

ACTIVE INTERACTORS

List of the fusions
PPI for parental proteins: TCF3	All fusions : CN419071; AL079531;
Proteins found in more fusions	RUNX1 (see 1 fusions); CREBBP (see 5 fusions); PRPF8 (see 3 fusions); KAT2B (see 1 fusions); VDR (see 2 fusions); IMMT (see 4 fusions); PRMT5 (see 2 fusions); TCF3 (see 3 fusions); MYOD1 (see 1 fusions); TRIM33 (see 1 fusions); ID3 (see 1 fusions); NEDD9 (see 1 fusions); TCF12 (see 1 fusions); KDM1A (see 2 fusions); DDX17 (see 3 fusions); PARP1 (see 1 fusions); EP300 (see 1 fusions); GSE1 (see 1 fusions); SLC9A3R1 (see 2 fusions); RUNX1T1 (see 1 fusions); RUNX1/RUNX1T1 (see 21 fusions); USF1 (see 3 fusions); RCOR1 (see 2 fusions); YY1 (see 2 fusions); CSTA (see 1 fusions);

List of active interactors

#	Name	Type	Number of PPI (degree)	Clustering Coefficient	Betweenness Centrality	Domains (Pfam, InterPro, SMART): description
1	TCF3	parental protein	134	0.033	15399.187	CDC45 (PF02724, IPR003874): CDC45-like protein HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain DUF3682 (PF12446, IPR022152): Protein of unknown function (DUF3682)
2	ALDH18A1	interactor	1	0	0	AA_kinase (PF00696, IPR001048): Amino acid kinase family Aldedh (PF00171, IPR015590): Aldehyde dehydrogenase family
3	ASB2	interactor	4	0.667	0.667	Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_4 (PF13637): Ankyrin repeats (many copies) Ank_5 (PF13857): Ankyrin repeats (many copies) SOCS_box (PF07525, IPR001496): SOCS box
4	ATOH8	interactor	1	0	0	HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
5	ATP2A3	interactor	1	0	0	Cation_ATPase_C (PF00689, IPR006068): Cation transporting ATPase, C-terminus Cation_ATPase_N (PF00690, IPR004014, SM00831): Cation transporter/ATPase, N-terminus E1-E2_ATPase (PF00122, IPR008250): E1-E2 ATPase Hydrolase_3 (PF08282, IPR023214): haloacid dehalogenase-like hydrolase HAD (PF12710): haloacid dehalogenase-like hydrolase Cation_ATPase (PF13246): Cation transport ATPase (P-type)
6	BCOR	oncoprotein	2	0	0	Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) BCOR (PF15808, IPR031628): BCL-6 co-repressor, non-ankyrin-repeat region PUFD (PF16553, IPR032365): BCORL-PCGF1-binding domain
7	BHLHA15	interactor	2	1.000	0	HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
8	BHLHE40	interactor	5	0.500	1.167	Hairy_orange (PF07527, IPR003650): Hairy Orange HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
9	C14orf166	interactor	1	0	0	RLL (PF10036, IPR019265): Putative carnitine deficiency-associated protein
10	C1QBP	interactor	6	0.333	9.000	MAM33 (PF02330, IPR003428): Mitochondrial glycoprotein DUF3053 (PF11254, IPR021413): Protein of unknown function (DUF3053)
11	CALM1	interactor	5	0.400	4.233	EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
12	CANX	interactor	5	0.600	4.000	Calreticulin (PF00262, IPR001580): Calreticulin family DUF1510 (PF07423, IPR009988): Protein of unknown function (DUF1510) TRAP_alpha (PF03896, IPR005595): Translocon-associated protein (TRAP), alpha subunit
13	CASP14	interactor	1	0	0	Peptidase_C14 (PF00656, IPR011600): Caspase domain
14	CBFA2T3	oncoprotein	8	0.714	3.210	NHR2 (PF08788, IPR014896): NHR2 domain like TAFH (PF07531, IPR003894, SM00549): NHR1 homology to TAF zf-MYND (PF01753, IPR002893): MYND finger Efg1 (PF10153, IPR019310): rRNA-processing protein Efg1 PRIMA1 (PF16101): Proline-rich membrane anchor 1
15	CCT2	interactor	2	1.000	0	Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
16	CHCHD3	interactor	1	0	0	DUF737 (PF05300, IPR007964): Protein of unknown function (DUF737) eIF3g (PF12353, IPR024675): Eukaryotic translation initiation factor 3 subunit G
17	COX7A2	interactor	2	1.000	0	COX7a (PF02238, IPR003177): Cytochrome c oxidase subunit VII
18	CPD	interactor	2	1.000	0	Peptidase_M14 (PF00246, IPR000834, SM00631): Zinc carboxypeptidase CarboxypepD_reg (PF13620): Carboxypeptidase regulatory-like domain
19	CREBBP	oncoprotein	15	0.473	21.460	Creb_binding (PF09030, IPR014744): Creb binding DUF902 (PF06001, IPR010303): Domain of Unknown Function (DUF902) Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region KIX (PF02172, IPR003101): KIX domain MAS20 (PF02064, IPR002056): MAS20 protein import receptor TPX2 (PF06886, IPR027329): Targeting protein for Xklp2 (TPX2) zf-TAZ (PF02135, IPR000197, SM00551): TAZ zinc finger ANAPC_CDC26 (PF10471, IPR018860): Anaphase-promoting complex APC subunit CDC26 HAT_KAT11 (PF08214, IPR013178): Histone acetylation protein Bromodomain (PF00439, IPR001487, SM00297): Bromodomain ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type DUF3729 (PF12526, IPR022202): Protein of unknown function (DUF3729) DUF4834 (PF16118, IPR032272): Domain of unknown function (DUF4834)
20	CSTA	oncoprotein	2	0	0	Cystatin (PF00031, IPR000010, SM00043): Cystatin domain
21	DAXX	oncoprotein	10	0.472	11.317	Daxx (PF03344, IPR005012): Daxx N-terminal Rassf1C-interacting domain Merozoite_SPAM (PF07133, IPR010784): Merozoite surface protein (SPAM) Nop14 (PF04147, IPR007276): Nop14-like family RF-1 (PF00472, IPR000352): RF-1 domain Vpu (PF00558, IPR008187): Vpu protein DUF3391 (PF11871, IPR021812): Domain of unknown function (DUF3391)
22	DDX17	protein found in more fusions	10	0.500	11.906	CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal DEAD (PF00270, IPR011545): DEAD/DEAH box helicase Ferritin (PF00210, IPR008331): Ferritin-like domain GRP (PF07172, IPR010800): Glycine rich protein family Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
23	DDX20	interactor	3	1.000	0	DEAD (PF00270, IPR011545): DEAD/DEAH box helicase Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
24	DNAJC10	interactor	1	0	0	DnaJ (PF00226, IPR001623, SM00271): DnaJ domain Thioredoxin (PF00085, IPR013766): Thioredoxin Thioredoxin_6 (PF13848): Thioredoxin-like domain
25	DNMT1	oncoprotein	9	0.571	5.010	BAH (PF01426, IPR001025, SM00439): BAH domain DMAP_binding (PF06464, IPR010506, SM01137): DMAP1-binding Domain DNA_methylase (PF00145, IPR001525): C-5 cytosine-specific DNA methylase zf-CXXC (PF02008, IPR002857): CXXC zinc finger domain DNMT1-RFD (PF12047, IPR022702): Cytosine specific DNA methyltransferase replication foci domain
26	EEF1A2	oncoprotein	2	1.000	0	GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2 GTP_EFTU_D3 (PF03143, IPR004160): Elongation factor Tu C-terminal domain
27	EIF5A	interactor	4	1.000	0	EFP_N (PF08207, IPR013185): Elongation factor P (EF-P) KOW-like domain eIF-5a (PF01287, IPR020189): Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold
28	ELAVL1	oncoprotein	26	0.160	223.957	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
29	ELK3	interactor	1	0	0	Ets (PF00178, IPR000418, SM00413): Ets-domain Translat_reg (PF01818, IPR002702): Bacteriophage translational regulator
30	EP300	oncoprotein	22	0.324	87.822	Creb_binding (PF09030, IPR014744): Creb binding DUF902 (PF06001, IPR010303): Domain of Unknown Function (DUF902) Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region KIX (PF02172, IPR003101): KIX domain RR_TM4-6 (PF06459, IPR009460): Ryanodine Receptor TM 4-6 TPX2 (PF06886, IPR027329): Targeting protein for Xklp2 (TPX2) zf-TAZ (PF02135, IPR000197, SM00551): TAZ zinc finger HAT_KAT11 (PF08214, IPR013178): Histone acetylation protein Bromodomain (PF00439, IPR001487, SM00297): Bromodomain ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type
31	ERAL1	interactor	2	1.000	0	GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain MMR_HSR1 (PF01926, IPR006073): 50S ribosome-binding GTPase KH_1 (PF00013, IPR004088, SM00322): KH domain
32	ERLIN2	interactor	5	0.500	5.000	Band_7 (PF01145, IPR001107, SM00244): SPFH domain / Band 7 family DUF4346 (PF14251, IPR025595): Domain of unknown function (DUF4346)
33	FBL	interactor	7	0.333	13.000	Fibrillarin (PF01269, IPR000692): Fibrillarin
34	FLG2	interactor	1	0	0	S_100 (PF01023, IPR013787): S-100/ICaBP type calcium binding domain EF-hand_7 (PF13499, IPR011992): EF-hand domain pair AP3D1 (PF06375): AP-3 complex subunit delta-1
35	FOXH1	interactor	3	0.667	1.000	Forkhead (PF00250, IPR001766, SM00339): Forkhead domain
36	GSE1	oncoprotein	7	0.667	2.050	CENP-B_dimeris (PF09026, IPR015115): Centromere protein B dimerisation domain DUF719 (PF05334, IPR007998): Protein of unknown function (DUF719) DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972) FYDLN_acid (PF09538, IPR012644): Protein of unknown function (FYDLN_acid) Pheromone (PF08015, IPR012597): Fungal mating-type pheromone Plasmodium_Vir (PF05795, IPR008780): Plasmodium vivax Vir protein Trypan_PARP (PF05887, IPR008882): Procyclic acidic repetitive protein (PARP) DUF3736 (PF12540, IPR022207): Protein of unknown function (DUF3736) AAA_11 (PF13086): AAA domain DUF4228 (PF14009, IPR025322): Domain of unknown function (DUF4228)
37	HAND1	interactor	2	1.000	0	HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
38	HAND2	interactor	4	1.000	0	HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
39	HDAC2	oncoprotein	21	0.295	89.950	Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain NARP1 (PF12569, IPR021183): NMDA receptor-regulated protein 1
40	HNRNPR	interactor	8	0.250	20.333	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 (PF11608, IPR024582): Limkain b1
41	ID1	interactor	6	0.533	4.917	HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
42	ID2	oncoprotein	12	0.291	33.336	HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
43	ID3	oncoprotein	5	0.833	0.250	HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
44	ID4	oncoprotein	2	1.000	0	HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain Lipase_3 (PF01764, IPR002921): Lipase (class 3)
45	IMMT	protein found in more fusions	8	0.381	11.286	Mitofilin (PF09731, IPR019133): Mitochondrial inner membrane protein
46	INO80E	interactor	3	0.667	0.667	NBP1 (PF08537, IPR013743): Fungal Nap binding protein NBP1
47	KAT2A	interactor	7	0.467	6.167	Acetyltransf_1 (PF00583, IPR000182): Acetyltransferase (GNAT) family PCAF_N (PF06466, IPR009464): PCAF (P300/CBP-associated factor) N-terminal domain Bromodomain (PF00439, IPR001487, SM00297): Bromodomain NICE-1 (PF15845, IPR031698): Cysteine-rich C-terminal 1 family
48	KAT2B	protein found in more fusions	16	0.362	46.555	Acetyltransf_1 (PF00583, IPR000182): Acetyltransferase (GNAT) family PCAF_N (PF06466, IPR009464): PCAF (P300/CBP-associated factor) N-terminal domain Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
49	KDM1A	protein found in more fusions	14	0.397	31.888	Amino_oxidase (PF01593, IPR002937): Flavin containing amine oxidoreductase CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain SWIRM (PF04433, IPR007526): SWIRM domain DUF4298 (PF14131, IPR025384): Domain of unknown function (DUF4298)
50	KIF18A	interactor	1	0	0	Kinesin (PF00225, IPR001752, SM00129): Kinesin motor domain DUF4005 (PF13178, IPR025064): Protein of unknown function (DUF4005)
51	LANCL2	interactor	1	0	0	Glyco_hydro_127 (PF07944, IPR012878): Beta-L-arabinofuranosidase, GH127 LANC_like (PF05147, IPR007822): Lanthionine synthetase C-like protein
52	LBR	interactor	2	1.000	0	ERG4_ERG24 (PF01222, IPR001171): Ergosterol biosynthesis ERG4/ERG24 family LBR_tudor (PF09465, IPR019023): Lamin-B receptor of TUDOR domain
53	LDB1	oncoprotein	5	0.800	1.000	LIM_bind (PF01803): LIM-domain binding protein
54	LGALS7	suppressor	2	1.000	0	Gal-bind_lectin (PF00337, IPR001079, SM00908): Galactoside-binding lectin
55	LMX1A	interactor	2	0	0	LIM (PF00412, IPR001781, SM00132): LIM domain Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
56	LYL1	oncoprotein	4	1.000	0	HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
57	MAPKAPK2	oncoprotein	4	1.000	0	Pkinase (PF00069, IPR000719): Protein kinase domain
58	MAPKAPK3	interactor	1	0	0	Pkinase (PF00069, IPR000719): Protein kinase domain
59	MEN1	oncoprotein	2	1.000	0	Menin (PF05053, IPR007747): Menin
60	MESP2	interactor	3	1.000	0	DUF1180 (PF06679, IPR009565): Protein of unknown function (DUF1180) HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
61	MRPL23	interactor	4	0.500	3.000	Ribosomal_L23 (PF00276, IPR013025): Ribosomal protein L23
62	MRPL37	interactor	5	0.600	3.333	PDCD9 (PF07147, IPR010793): Mitochondrial 28S ribosomal protein S30 (PDCD9)
63	MRPL39	interactor	6	0.467	7.333	TGS (PF02824, IPR004095): TGS domain DUF2469 (PF10611, IPR019592): Protein of unknown function (DUF2469)
64	MRPL44	interactor	5	0.500	4.333	dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif Ribonuclease_3 (PF00636, IPR000999, SM00535): Ribonuclease III domain
65	MRPL49	interactor	3	1.000	0	Img2 (PF05046, IPR007740): Mitochondrial large subunit ribosomal protein (Img2)
66	MYF5	interactor	3	0.667	0.400	Auxin_repressed (PF05564, IPR008406): Dormancy/auxin associated protein Basic (PF01586, IPR002546, SM00520): Myogenic Basic domain HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain Myf5 (PF12232, IPR022032): Myogenic determination factor 5
67	MYF6	interactor	2	1.000	0	Basic (PF01586, IPR002546, SM00520): Myogenic Basic domain HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain Myf5 (PF12232, IPR022032): Myogenic determination factor 5
68	MYL6B	interactor	1	0	0	SapB_1 (PF05184, IPR007856): Saposin-like type B, region 1 EF-hand_6 (PF13405, IPR002048): EF-hand domain EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
69	MYO1B	interactor	1	0	0	IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif Myosin_TH1 (PF06017, IPR010926): Unconventional myosin tail, actin- and lipid-binding RNA_pol (PF00940, IPR002092): DNA-dependent RNA polymerase Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain) AAA_23 (PF13476): AAA domain
70	MYOD1	oncoprotein	14	0.333	38.510	Basic (PF01586, IPR002546, SM00520): Myogenic Basic domain HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain Mfp-3 (PF04202, IPR007328): Foot protein 3 Myf5 (PF12232, IPR022032): Myogenic determination factor 5
71	MYOG	interactor	4	0.667	1.167	Basic (PF01586, IPR002546, SM00520): Myogenic Basic domain HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
72	NDUFB4	interactor	1	0	0	NDUF_B4 (PF07225, IPR009866): NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4)
73	NEDD9	protein found in more fusions	3	1.000	0	Serine_rich (PF08824, IPR014928): Serine rich protein interaction domain DUF3513 (PF12026, IPR021901): Domain of unknown function (DUF3513) SH3_9 (PF14604, IPR001452): Variant SH3 domain
74	NEUROD1	interactor	4	1.000	0	HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain YL1 (PF05764, IPR008895): YL1 nuclear protein Neuro_bHLH (PF12533, IPR022575): Neuronal helix-loop-helix transcription factor
75	NHLH1	interactor	3	0.667	0.667	HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
76	NHLH2	interactor	1	0	0	HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
77	PARP1	suppressor	14	0.410	28.396	BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain PADR1 (PF08063, IPR012982): PADR1 (NUC008) domain PARP (PF00644, IPR012317): Poly(ADP-ribose) polymerase catalytic domain PARP_reg (PF02877, IPR004102): Poly(ADP-ribose) polymerase, regulatory domain WGR (PF05406, IPR008893, SM00773): WGR domain zf-PARP (PF00645, IPR001510): Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region
78	PCBP1	oncoprotein	3	0.667	1.000	Bac_chlorC (PF02043, IPR001470): Bacteriochlorophyll C binding protein KH_2 (PF07650, IPR004044): KH domain KH_1 (PF00013, IPR004088, SM00322): KH domain
79	PIP	interactor	1	0	0	SVA (PF05326, IPR007990): Seminal vesicle autoantigen (SVA)
80	PON2	interactor	1	0	0	Arylesterase (PF01731, IPR002640): Arylesterase
81	PRMT5	protein found in more fusions	7	0.400	7.833	PRMT5 (PF05185, IPR025799): PRMT5 arginine-N-methyltransferase
82	PRPF8	oncoprotein	5	0.500	3.000	PRO8NT (PF08082, IPR012591): PRO8NT (NUC069), PrP8 N-terminal domain PROCN (PF08083, IPR012592): PROCN (NUC071) domain PROCT (PF08084, IPR012984): PROCT (NUC072) domain RRM_4 (PF10598, IPR019582): RNA recognition motif of the spliceosomal PrP8 U5_2-snRNA_bdg (PF10597, IPR019581): U5-snRNA binding site 2 of PrP8 U6-snRNA_bdg (PF10596, IPR019580): U6-snRNA interacting domain of PrP8 JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease PRP8_domainIV (PF12134, IPR021983): PRP8 domain IV core
83	PSMD4	interactor	3	1.000	0	UIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif VWA_2 (PF13519, IPR002035): von Willebrand factor type A domain
84	PTF1A	interactor	4	0.500	1.400	HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
85	RB1	oncoprotein	14	0.396	31.736	RB_A (PF01858, IPR002720): Retinoblastoma-associated protein A domain RB_B (PF01857, IPR002719): Retinoblastoma-associated protein B domain Rb_C (PF08934, IPR015030): Rb C-terminal domain DUF3452 (PF11934, IPR024599): Domain of unknown function (DUF3452) DUF4592 (PF15262, IPR028030): Domain of unknown function (DUF4592)
86	RBM39	oncoprotein	4	0.500	3.000	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MIP-T3 (PF10243): Microtubule-binding protein MIP-T3 RBM39linker (PF15519, IPR029123): linker between RRM2 and RRM3 domains in RBM39 protein
87	RCOR1	protein found in more fusions	6	0.800	1.333	DivIC (PF04977, IPR007060): Septum formation initiator ELM2 (PF01448, IPR000949): ELM2 domain Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain FAM76 (PF16046, IPR032017): FAM76 protein
88	RNF14	interactor	4	0.667	0.500	IBR (PF01485, IPR002867, SM00647): IBR domain, a half RING-finger domain RWD (PF05773, IPR006575, SM00591): RWD domain T5orf172 (PF10544, IPR018306, SM00974): T5orf172 domain zf-RING_5 (PF14634, IPR001841): zinc-RING finger domain zf-RING_11 (PF17123, IPR001841): RING-like zinc finger
89	RPL13	interactor	7	0.762	3.667	Ribosomal_L13e (PF01294, IPR001380): Ribosomal protein L13e
90	RPL14	interactor	7	0.762	4.667	KOW (PF00467, IPR005824, SM00739): KOW motif Ribosomal_L14e (PF01929, IPR002784): Ribosomal protein L14 UPF0688 (PF15772, IPR031530): UPF0688 family
91	RPL23A	interactor	7	0.857	1.400	Ribosomal_L23 (PF00276, IPR013025): Ribosomal protein L23 Ribosomal_L23eN (PF03939, IPR005633): Ribosomal protein L23, N-terminal domain
92	RPL24	interactor	7	0.857	1.400	MAS20 (PF02064, IPR002056): MAS20 protein import receptor Ribosomal_L24e (PF01246, IPR000988): Ribosomal protein L24e
93	RPL31	interactor	7	0.762	4.667	Ribosomal_L31e (PF01198, IPR000054): Ribosomal protein L31e
94	RPL36A	interactor	1	0	0	NOB1_Zn_bind (PF08772, IPR014881): Nin one binding (NOB1) Zn-ribbon like Ribosomal_L44 (PF00935, IPR000552): Ribosomal protein L44
95	RPL37	interactor	2	1.000	0	Ribosomal_L37e (PF01907, IPR001569): Ribosomal protein L37e
96	RPN2	interactor	3	1.000	0	Ribophorin_II (PF05817, IPR008814): Oligosaccharyltransferase subunit Ribophorin II
97	RPS13	interactor	10	0.489	20.400	Ribosomal_S13_N (PF08069, IPR012606): Ribosomal S13/S15 N-terminal domain Ribosomal_S15 (PF00312, IPR000589): Ribosomal protein S15
98	RUNX1	oncoprotein	16	0.419	33.601	Runt (PF00853, IPR013524): Runt domain RunxI (PF08504, IPR013711): Runx inhibition domain DUF3037 (PF11236, IPR021398): Protein of unknown function (DUF3037)
99	RUNX1T1	oncoprotein	11	0.533	10.344	NHR2 (PF08788, IPR014896): NHR2 domain like TAFH (PF07531, IPR003894, SM00549): NHR1 homology to TAF zf-MYND (PF01753, IPR002893): MYND finger DUF3731 (PF12531, IPR021030): DNA-K related protein
100	SAFB	suppressor	3	0.667	1.000	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SAP (PF02037, IPR003034, SM00513): SAP domain Ferlin_C (PF16165, IPR032362): Ferlin C-terminus
101	SCX	interactor	1	0	0	CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
102	SERPINH1	interactor	4	0.833	0.667	Serpin (PF00079, IPR023796, SM00093): Serpin (serine protease inhibitor)
103	SETSIP	interactor	1	0	0	NAP (PF00956, IPR002164): Nucleosome assembly protein (NAP) Nop14 (PF04147, IPR007276): Nop14-like family
104	SF3A3	interactor	5	0.400	5.667	DUF3449 (PF11931, IPR024598): Domain of unknown function (DUF3449) SF3a60_bindingd (PF12108, IPR021966): Splicing factor SF3a60 binding domain Telomere_Sde2_2 (PF13297): Telomere stability C-terminal PBP1_TM (PF14812, IPR032730): Transmembrane domain of transglycosylase PBP1 at N-terminal SF3A3 (PF16837, IPR031774): Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9
105	SKP2	oncoprotein	8	0.464	12.008	LRR_1 (PF00560, IPR001611): Leucine Rich Repeat LRR_2 (PF07723, IPR013101): Leucine Rich Repeat LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies) F-box-like (PF12937, IPR001810): F-box-like LRR_6 (PF13516, IPR001611): Leucine Rich repeat LRR_8 (PF13855, IPR001611): Leucine rich repeat
106	SLC25A10	interactor	1	0	0	Mito_carr (PF00153, IPR018108): Mitochondrial carrier protein
107	SLC25A4	interactor	1	0	0	Mito_carr (PF00153, IPR018108): Mitochondrial carrier protein
108	SLC9A3R1	oncoprotein	3	1.000	0	EBP50_C (PF09007, IPR015098): EBP50, C-terminal PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
109	SON	interactor	3	0.667	1.000	Asp-B-Hydro_N (PF05279, IPR007943): Aspartyl beta-hydroxylase N-terminal region G-patch (PF01585, IPR000467, SM00443): G-patch domain tRNA_synt_1c_R2 (PF04557, IPR007638): Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 Eapp_C (PF10238, IPR019370): E2F-associated phosphoprotein DND1_DSRM (PF14709): double strand RNA binding domain from DEAD END PROTEIN 1 GREB1 (PF15782, IPR028422): Gene regulated by oestrogen in breast cancer RSRP (PF17069): Arginine/Serine-Rich protein 1
110	SOX2	oncoprotein	10	0.417	16.371	HMG_box (PF00505, IPR009071, SM00398): HMG (high mobility group) box SOXp (PF12336, IPR022097): SOX transcription factor
111	SPIN1	interactor	3	0.667	1.000	Spin-Ssty (PF02513, IPR003671): Spin/Ssty Family
112	SSBP1	interactor	5	0.500	2.667	SSB (PF00436, IPR000424): Single-strand binding protein family
113	STK38	interactor	4	0.667	0.667	MEKHLA (PF08670, IPR013978): MEKHLA domain Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
114	SUPT3H	interactor	5	0.800	0.900	TFIID-18kDa (PF02269, IPR003195): Transcription initiation factor IID, 18kD subunit DUF4093 (PF13331, IPR025156): Domain of unknown function (DUF4093)
115	TADA2A	interactor	7	0.429	11.067	SWIRM (PF04433, IPR007526): SWIRM domain Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
116	TAL1	oncoprotein	19	0.333	70.889	HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain SelK_SelG (PF10961, IPR024491): Selenoprotein SelK_SelG
117	TCAF1	interactor	1	0	0	Peptidase_M60 (PF13402, IPR031161): Peptidase M60, enhancin and enhancin-like
118	TCF12	oncoprotein	21	0.253	106.968	HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
119	TCF21	interactor	3	1.000	0	HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
120	TCF24	interactor	2	1.000	0	HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
121	TCF4	suppressor	30	0.147	317.255	CDC45 (PF02724, IPR003874): CDC45-like protein HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
122	TET2	interactor	1	0	0	Tet_JBP (PF12851, IPR024779): Oxygenase domain of the 2OGFeDO superfamily
123	TFF3	interactor	1	0	0	Trefoil (PF00088, IPR000519, SM00018): Trefoil (P-type) domain
124	TIMM50	interactor	3	0.667	1.000	NIF (PF03031, IPR004274): NLI interacting factor-like phosphatase
125	TLE1	interactor	4	0.667	0.222	TLE_N (PF03920, IPR005617): Groucho/TLE N-terminal Q-rich domain WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
126	TRIM33	oncoprotein	14	0.474	23.746	PHD (PF00628, IPR019787, SM00249): PHD-finger Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein Siva (PF05458, IPR022773): Cd27 binding protein (Siva) Spectrin (PF00435, IPR002017): Spectrin repeat TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger Bromodomain (PF00439, IPR001487, SM00297): Bromodomain zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger
127	TRRAP	interactor	6	0.600	4.133	BALF1 (PF06861, IPR010677): BALF1 protein BP28CT (PF08146, IPR012954, SM01036): BP28CT (NUC211) domain DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region FAT (PF02259, IPR003151): FAT domain FATC (PF02260, IPR003152): FATC domain TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat PI3_PI4_kinase (PF00454, IPR000403, SM00146): Phosphatidylinositol 3- and 4-kinase DUF3361 (PF11841, IPR024574): Domain of unknown function (DUF3361) DUF3385 (PF11865, IPR024585): Domain of unknown function (DUF3385) CLASP_N (PF12348, IPR024395): CLASP N terminal Sec7_N (PF12783, IPR032691): Guanine nucleotide exchange factor in Golgi transport N-terminal HEAT_EZ (PF13513): HEAT-like repeat TRC8_N (PF13705, IPR025754): TRC8 N-terminal domain ACDC (PF14733, IPR028078): AP2-coincident C-terminal
128	TWIST1	oncoprotein	7	0.571	4.367	ACC_epsilon (PF13822, IPR032716): Acyl-CoA carboxylase epsilon subunit PRR20 (PF15708, IPR031439): Proline-rich protein family 20 FXR_C1 (PF16096, IPR032172): Fragile X-related 1 protein C-terminal region 2
129	UBE2I	interactor	14	0.333	37.274	UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
130	UQCRC2	oncoprotein	5	0.500	4.667	Peptidase_M16 (PF00675, IPR011765): Insulinase (Peptidase family M16) Peptidase_M16_C (PF05193, IPR007863): Peptidase M16 inactive domain
131	USF1	oncoprotein	7	0.667	2.556	HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain Rootletin (PF15035): Ciliary rootlet component, centrosome cohesion
132	VDR	suppressor	8	0.524	6.169	zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
133	XPO1	interactor	15	0.276	65.467	CRM1_C (PF08767, IPR014877, SM01102): CRM1 C terminal Hydrolase_3 (PF08282, IPR023214): haloacid dehalogenase-like hydrolase IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain Xpo1 (PF08389, IPR013598): Exportin 1-like protein Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region
134	YY1	protein found in more fusions	11	0.533	12.856	zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_4 (PF13894): C2H2-type zinc finger Keratin_2_tail (PF16210, IPR032449): Keratin type II cytoskeletal 1 tail

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