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Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

Powered by Cytoscape Web for: parental proteins TACO1, RP11-289H16.1 (from a repository: Mon May 4 19:56:56 2020)

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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)10
The number (and %) of the onco-proteins3 (30.00 %)
The number (and %) of the tumor suppressors0 (0.00 %)
Total number of binary PPIs (saturation %)12 (26.67 %)
The number (and %) of affected PPIs8 (66.67 %)
The number of possible different fusions4
PPI diameter2
PPI radiusinf
The average degree of PPI1.800
Assortativity coefficient-0.5000
The network average Clustering coefficient0.204
The number (and %) of a zero Clustering coefficients7 (70.00 %)
The number (and %) of a zero Betweenness Centrality9 (90.00 %)


List of the fusions

PPI for parental proteins: RP11-289H16.1,TACO1 All fusions
Proteins found in more fusions SAT1 (see 6 fusions); APP (see 5 fusions); GAPDH (see 5 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Domains (Pfam, InterPro, SMART): description
1 RP11-289H16.1interactor000NA
2 TACO1parental protein80.03654.000Transcrip_reg (PF01709, IPR002876): Transcriptional regulator
3 APPprotein found in more fusions31.0000APP_N (PF02177, IPR015849, SM00006): Amyloid A4 N-terminal heparin-binding
Beta-APP (PF03494, IPR013803): Beta-amyloid peptide (beta-APP)
BUD22 (PF09073, IPR015158): BUD22
IncA (PF04156, IPR007285): IncA protein
Kunitz_BPTI (PF00014, IPR002223, SM00131): Kunitz/Bovine pancreatic trypsin inhibitor domain
APP_amyloid (PF10515, IPR019543): beta-amyloid precursor protein C-terminus
APP_Cu_bd (PF12924, IPR011178): Copper-binding of amyloid precursor, CuBD
APP_E2 (PF12925, IPR024329): E2 domain of amyloid precursor protein
4 CAB39interactor100Mo25 (PF08569, IPR013878): Mo25-like
5 FOXD4interactor100Forkhead (PF00250, IPR001766, SM00339): Forkhead domain
6 GAPDHoncoprotein31.0000Gp_dh_C (PF02800, IPR020829): Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain
Gp_dh_N (PF00044, IPR020828, SM00846): Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain
OstA (PF03968, IPR005653): OstA-like protein
7 HPDLinteractor100Glyoxalase_3 (PF13468, IPR025870): Glyoxalase-like domain
Glyoxalase_4 (PF13669): Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
8 SAT1protein found in more fusions200Acetyltransf_1 (PF00583, IPR000182): Acetyltransferase (GNAT) family
9 SEC22Binteractor100Synaptobrevin (PF00957, IPR001388): Synaptobrevin
Longin (PF13774, IPR010908): Regulated-SNARE-like domain
10 SLC9A3R2interactor100EBP50_C (PF09007, IPR015098): EBP50, C-terminal
GRASP55_65 (PF04495, IPR024958): GRASP55/65 PDZ-like domain
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)

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