Find Fusion Network

Enter
Fusion ID:
Protein names:


Level of PPIs:
or Upload text file:
Update repository
Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

Powered by Cytoscape Web for: parental proteins SUV39H1 (from a repository: Fri Nov 11 23:16:35 2016)
Examples

Cytoscape Web will replace the contents your graph
PPI Properties:

Click on nodes
or edges

Layout Tree
Circle
Radial
Force Directed
Preset
Export graph
PDF file
SVG file
SIF file
XML file
GraphML file

Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)149
The number (and %) of the onco-proteins33 (22.15 %)
The number (and %) of the tumor suppressors31 (20.81 %)
Total number of binary PPIs (saturation %)632 (5.73 %)
The number (and %) of affected PPIs149 (23.58 %)
The number of possible different fusions19
PPI diameter2
PPI radius1
The average degree of PPI7.826
Assortativity coefficient-0.3701
The network average Clustering coefficient0.558
The number (and %) of a zero Clustering coefficients14 (9.40 %)
The number (and %) of a zero Betweenness Centrality42 (28.19 %)

ACTIVE INTERACTORS


List of the fusions

PPI for parental proteins: SUV39H1 All fusions
: L08238;
Proteins found in more fusions CEP70 (see 1 fusions); OPA3 (see 2 fusions); HDAC4 (see 1 fusions); FYN (see 1 fusions); MYC (see 1 fusions); RUNX1 (see 1 fusions); TNFAIP1 (see 1 fusions); MALT1 (see 1 fusions); KIF11 (see 1 fusions); RARA (see 4 fusions); MYOD1 (see 1 fusions); KDM1A (see 2 fusions); HDAC5 (see 1 fusions); EZH2 (see 1 fusions); ZNF451 (see 1 fusions); SUV39H1 (see 1 fusions); THRA (see 3 fusions); SMAD3 (see 3 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 SUV39H1parental protein1490.04016680.369Chromo (PF00385, IPR023780, SM00298): Chromo (CHRromatin Organisation MOdifier) domain
Pre-SET (PF05033, IPR007728): Pre-SET motif
SET (PF00856, IPR001214, SM00317): SET domain
2 AKAP5interactor21.0000WSK (PF03832, IPR001573): WSK motif
3 ATE1interactor100ATE_C (PF04377, IPR007472): Arginine-tRNA-protein transferase, C terminus
ATE_N (PF04376, IPR007471): Arginine-tRNA-protein transferase, N terminus
4 ATF3suppressor80.6671.932bZIP_1 (PF00170, IPR004827): bZIP transcription factor
5 ATP6V1B1interactor31.0000ATP-synt_ab (PF00006, IPR000194): ATP synthase alpha/beta family, nucleotide-binding domain
ATP-synt_ab_N (PF02874, IPR004100): ATP synthase alpha/beta family, beta-barrel domain
DUF3533 (PF12051, IPR022703): Protein of unknown function (DUF3533)
6 BAHD1interactor60.5335.119BAH (PF01426, IPR001025, SM00439): BAH domain
7 BCL11Boncoprotein70.7141.034FYVE (PF01363, IPR000306, SM00064): FYVE zinc finger
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-CCHC_2 (PF13696, IPR025829): Zinc knuckle
zf-H2C2_5 (PF13909): C2H2-type zinc-finger domain
8 BRINP1suppressor50.5001.037MACPF (PF01823, IPR020864, SM00457): MAC/Perforin domain
9 C17orf82interactor30.6670.105NA
10 C4orf17interactor21.0000SPATIAL (PF15256): SPATIAL
11 C8orf74interactor30.6670.105CLAMP (PF14769, IPR032727): Flagellar C1a complex subunit C1a-32
12 CABIN1interactor50.8000.583FAT (PF02259, IPR003151): FAT domain
MEF2_binding (PF09047, IPR015134): MEF2 binding
TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat
TPR_8 (PF13181, IPR019734): Tetratricopeptide repeat
TPR_11 (PF13414, IPR011990): TPR repeat
TPR_12 (PF13424): Tetratricopeptide repeat
TPR_17 (PF13431): Tetratricopeptide repeat
13 CBX1interactor110.5786.459Chromo (PF00385, IPR023780, SM00298): Chromo (CHRromatin Organisation MOdifier) domain
Chromo_shadow (PF01393, IPR008251, SM00300): Chromo shadow domain
14 CBX4oncoprotein70.4004.833Chromo (PF00385, IPR023780, SM00298): Chromo (CHRromatin Organisation MOdifier) domain
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
SelP_N (PF04592, IPR007671): Selenoprotein P, N terminal region
CBX7_C (PF17218): CBX family C-terminal motif
15 CBX5suppressor210.26396.097Chromo (PF00385, IPR023780, SM00298): Chromo (CHRromatin Organisation MOdifier) domain
Chromo_shadow (PF01393, IPR008251, SM00300): Chromo shadow domain
16 CCDC151interactor21.0000DUF16 (PF01519, IPR002862): Protein of unknown function DUF16
Radial_spoke_3 (PF06098, IPR009290): Radial spoke protein 3
SAE2 (PF08573, IPR013882): DNA repair protein endonuclease SAE2/CtIP C-terminus
DUF2721 (PF11026, IPR021279): Protein of unknown function (DUF2721)
TMF_DNA_bd (PF12329, IPR022092): TATA element modulatory factor 1 DNA binding
DUF4140 (PF13600, IPR025554): N-terminal domain of unknown function (DUF4140)
Nup54 (PF13874, IPR025712): Nucleoporin complex subunit 54
PRKG1_interact (PF15898, IPR031775): cGMP-dependent protein kinase interacting domain
17 CDC23interactor40.6670.286ANAPC8 (PF04049, IPR007192): Anaphase promoting complex subunit 8 / Cdc23
DUF772 (PF05598, IPR008490): Transposase domain (DUF772)
Menin (PF05053, IPR007747): Menin
TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat
TPR_6 (PF13174, IPR019734): Tetratricopeptide repeat
TPR_7 (PF13176, IPR019734): Tetratricopeptide repeat
TPR_11 (PF13414, IPR011990): TPR repeat
TPR_14 (PF13428): Tetratricopeptide repeat
TPR_19 (PF14559): Tetratricopeptide repeat
18 CDC73suppressor70.4296.475CDC73_C (PF05179, IPR007852): RNA pol II accessory factor, Cdc73 family, C-terminal
CDC73_N (PF16050, IPR032041): Paf1 complex subunit CDC73 N-terminal
19 CDCA4interactor40.6671.105SERTA (PF06031, IPR009263): SERTA motif
20 CDCA7Linteractor80.28610.617zf-4CXXC_R1 (PF10497, IPR018866): Zinc-finger domain of monoamine-oxidase A repressor R1
SpoIIIAH (PF12685, IPR024232): SpoIIIAH-like protein
21 CEP70protein found in more fusions90.35714.900IncA (PF04156, IPR007285): IncA protein
Mog1 (PF04603, IPR007681): Ran-interacting Mog1 protein
Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein
Uso1_p115_C (PF04871, IPR006955): Uso1 / p115 like vesicle tethering protein, C terminal region
Colicin-DNase (PF12639, IPR024622): DNase/tRNase domain of colicin-like bacteriocin
22 CFAP100interactor21.0000DNA_photolyase (PF00875, IPR006050): DNA photolyase
DUF342 (PF03961, IPR005646): Protein of unknown function (DUF342)
Peroxin-13_N (PF04088, IPR007223): Peroxin 13, N-terminal region
DUF4200 (PF13863, IPR025252): Domain of unknown function (DUF4200)
STAC2_u1 (PF16664): Unstructured on SH3 and cysteine-rich domain-containing protein 2
23 CLK3interactor200Pkinase (PF00069, IPR000719): Protein kinase domain
SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein
24 CRBNinteractor21.0000LON_substr_bdg (PF02190, IPR003111, SM00464): ATP-dependent protease La (LON) substrate-binding domain
Yippee-Mis18 (PF03226, IPR004910): Yippee zinc-binding/DNA-binding /Mis18, centromere assembly
25 CRELD2interactor100EGF (PF00008, IPR000742, SM00181): EGF-like domain
EGF_CA (PF07645, IPR001881, SM00179): Calcium-binding EGF domain
VSP (PF03302, IPR005127): Giardia variant-specific surface protein
Laminin_EGF (PF00053, IPR002049, SM00180): Laminin EGF domain
DUF3456 (PF11938, IPR021852): TLR4 regulator and MIR-interacting MSAP
cEGF (PF12662, IPR026823): Complement Clr-like EGF-like
26 CTNNB1oncoprotein120.39425.144Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
Atx10homo_assoc (PF09759, IPR019156): Spinocerebellar ataxia type 10 protein domain
DUF3361 (PF11841, IPR024574): Domain of unknown function (DUF3361)
HEAT_EZ (PF13513): HEAT-like repeat
27 DAXXoncoprotein140.30835.186Daxx (PF03344, IPR005012): Daxx N-terminal Rassf1C-interacting domain
Merozoite_SPAM (PF07133, IPR010784): Merozoite surface protein (SPAM)
Nop14 (PF04147, IPR007276): Nop14-like family
RF-1 (PF00472, IPR000352): RF-1 domain
Vpu (PF00558, IPR008187): Vpu protein
DUF3391 (PF11871, IPR021812): Domain of unknown function (DUF3391)
28 DBF4Binteractor40.5001.400BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain
zf-DBF (PF07535, IPR006572, SM00586): DBF zinc finger
29 DCAF8interactor40.5002.333DUF1635 (PF07795, IPR012862): Protein of unknown function (DUF1635)
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
DUF4661 (PF15576, IPR029073): Domain of unknown function (DUF4661)
30 DNMT1suppressor180.51523.505BAH (PF01426, IPR001025, SM00439): BAH domain
DMAP_binding (PF06464, IPR010506, SM01137): DMAP1-binding Domain
DNA_methylase (PF00145, IPR001525): C-5 cytosine-specific DNA methylase
zf-CXXC (PF02008, IPR002857): CXXC zinc finger domain
DNMT1-RFD (PF12047, IPR022702): Cytosine specific DNA methyltransferase replication foci domain
31 DNMT3Asuppressor140.51619.833DNA_methylase (PF00145, IPR001525): C-5 cytosine-specific DNA methylase
PWWP (PF00855, IPR000313, SM00293): PWWP domain
32 DNMT3Bsuppressor140.51618.601DNA_methylase (PF00145, IPR001525): C-5 cytosine-specific DNA methylase
PWWP (PF00855, IPR000313, SM00293): PWWP domain
33 ELOF1interactor21.0000Elf1 (PF05129, IPR007808): Transcription elongation factor Elf1 like
34 ESCO1interactor51.0000TMPIT (PF07851, IPR012926): TMPIT-like protein
zf-C2H2_3 (PF13878, IPR028005): zinc-finger of acetyl-transferase ESCO
Acetyltransf_13 (PF13880, IPR028009): ESCO1/2 acetyl-transferase
GOLD_2 (PF13897, IPR009038): Golgi-dynamics membrane-trafficking
35 ESCO2interactor60.5334.015Acetyltransf_1 (PF00583, IPR000182): Acetyltransferase (GNAT) family
zf-C2H2_3 (PF13878, IPR028005): zinc-finger of acetyl-transferase ESCO
Acetyltransf_13 (PF13880, IPR028009): ESCO1/2 acetyl-transferase
36 ESR1suppressor220.38668.931Oest_recep (PF02159, IPR001292): Oestrogen receptor
zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains)
Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
ESR1_C (PF12743, IPR024736): Oestrogen-type nuclear receptor final C-terminal
37 EZH2suppressor270.308140.688CDC45 (PF02724, IPR003874): CDC45-like protein
TCR (PF03638, IPR005172, SM01114): Tesmin/TSO1-like CXC domain, cysteine-rich domain
SET (PF00856, IPR001214, SM00317): SET domain
EZH2_WD-Binding (PF11616, IPR021654): WD repeat binding protein EZH2
Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal
38 FGD5interactor100FYVE (PF01363, IPR000306, SM00064): FYVE zinc finger
Peptidase_S48 (PF03574, IPR005319): Peptidase family S48
PH (PF00169, IPR001849, SM00233): PH domain
RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain
DZR (PF12773, IPR025874): Double zinc ribbon
39 FOXR2interactor21.0000Forkhead (PF00250, IPR001766, SM00339): Forkhead domain
40 FRMD6interactor21.0000FERM_C (PF09380, IPR018980): FERM C-terminal PH-like domain
FERM_M (PF00373, IPR019748): FERM central domain
FERM_N (PF09379, IPR018979): FERM N-terminal domain
HTH_24 (PF13412, IPR011991): Winged helix-turn-helix DNA-binding
41 FUSsuppressor80.5009.733Herpes_PAP (PF03325, IPR004997): Herpesvirus polymerase accessory protein
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
SVS_QK (PF10578, IPR018942): Seminal vesicle protein repeat
zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others
Limkain-b1 (PF11608, IPR024582): Limkain b1
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
Keratin_2_head (PF16208, IPR032444): Keratin type II head
42 FYNoncoprotein50.5001.505Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
SH2 (PF00017, IPR000980, SM00252): SH2 domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
43 GFI1Boncoprotein50.5003.619zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger
44 GPATCH2Linteractor50.5004.286NA
45 GTF2H2C_2interactor100C1_4 (PF07975, IPR004595, SM01047): TFIIH C1-like domain
Prim_Zn_Ribbon (PF08273, IPR013237, SM00778): Zinc-binding domain of primase-helicase
Ssl1 (PF04056, IPR007198): Ssl1-like
zf-HIT (PF04438, IPR007529): HIT zinc finger
UPF0547 (PF10571, IPR018886): Uncharacterised protein family UPF0547
zf-C2H2_4 (PF13894): C2H2-type zinc finger
46 GTPBP2interactor30.6670.105GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain
GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2
47 H3F3Aoncoprotein120.36426.214Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
48 H3F3Concoprotein40.5001.772Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
49 HDAC1suppressor410.223377.420FSAP_sig_propep (PF03032, IPR004275): Frog skin active peptide family signal and propeptide
Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
50 HDAC2suppressor270.314120.203Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
NARP1 (PF12569, IPR021183): NMDA receptor-regulated protein 1
51 HDAC3suppressor240.249114.486Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
52 HDAC4oncoprotein150.40728.833Borrelia_P83 (PF05262, IPR007926): Borrelia P83/100 protein
Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
HDAC4_Gln (PF12203, IPR024643): Glutamine rich N terminal domain of histone deacetylase 4
53 HDAC5protein found in more fusions150.50519.888Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
NOA36 (PF06524, IPR010531): NOA36 protein
Activator_LAG-3 (PF11498, IPR021587): Transcriptional activator LAG-3
HDAC4_Gln (PF12203, IPR024643): Glutamine rich N terminal domain of histone deacetylase 4
54 HDLBPoncoprotein40.5001.567BMC (PF00936, IPR000249, SM00877): BMC domain
KH_1 (PF00013, IPR004088, SM00322): KH domain
KH_4 (PF13083): KH domain
KH_5 (PF13184, IPR025249): NusA-like KH domain
SLS (PF14611, IPR032741): Mitochondrial inner-membrane-bound regulator
DUF4530 (PF15039, IPR029202): Domain of unknown function (DUF4530)
55 HIST1H3Ainteractor250.275131.344Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
56 HIST2H3Ainteractor50.5003.686Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
57 HOOK2interactor200HOOK (PF05622, IPR008636): HOOK protein
58 HOXA1interactor40.6670.105Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
59 HOXC4interactor21.0000Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
60 ID1interactor30.6671.000HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
61 ID2oncoprotein100.30617.458HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
62 IGFBP4suppressor21.0000IGFBP (PF00219, IPR000867, SM00121): Insulin-like growth factor binding protein
Thyroglobulin_1 (PF00086, IPR000716, SM00211): Thyroglobulin type-1 repeat
63 IL16oncoprotein41.0000PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
SUZ (PF12752, IPR024771): SUZ domain
64 ING4suppressor40.6670.222PHD (PF00628, IPR019787, SM00249): PHD-finger
SOGA (PF11365, IPR027881): Protein SOGA
ING (PF12998, IPR024610): Inhibitor of growth proteins N-terminal histone-binding
zf-HC5HC2H (PF13771): PHD-like zinc-binding domain
65 INTS2interactor31.0000INTS2 (PF14750, IPR029321): Integrator complex subunit 2
66 KDM1Aprotein found in more fusions690.0592003.270Amino_oxidase (PF01593, IPR002937): Flavin containing amine oxidoreductase
CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain
SWIRM (PF04433, IPR007526): SWIRM domain
DUF4298 (PF14131, IPR025384): Domain of unknown function (DUF4298)
67 KIF11protein found in more fusions60.4004.083Baculo_PEP_C (PF04513, IPR007601): Baculovirus polyhedron envelope protein, PEP, C terminus
COG2 (PF06148, IPR024602): COG (conserved oligomeric Golgi) complex component, COG2
DUF106 (PF01956, IPR002809): Integral membrane protein DUF106
DUF16 (PF01519, IPR002862): Protein of unknown function DUF16
Gag_p17 (PF00540, IPR000071): gag gene protein p17 (matrix protein)
Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein
KxDL (PF10241, IPR019371): Uncharacterized conserved protein
Kinesin (PF00225, IPR001752, SM00129): Kinesin motor domain
DUF3510 (PF12022, IPR024603): Domain of unknown function (DUF3510)
Microtub_bind (PF13931, IPR025901): Kinesin-associated microtubule-binding
68 KLF15interactor21.0000zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
69 KLHDC4interactor21.0000Kelch_2 (PF07646, IPR011498): Kelch motif
Kelch_1 (PF01344, IPR006652, SM00612): Kelch motif
Kelch_3 (PF13415): Galactose oxidase, central domain
Kelch_4 (PF13418): Galactose oxidase, central domain
Kelch_5 (PF13854): Kelch motif
YqzE (PF14038, IPR025622): YqzE-like protein
70 KLHL20interactor40.6671.000BACK (PF07707, IPR011705, SM00875): BTB And C-terminal Kelch
BTB (PF00651, IPR013069, SM00225): BTB/POZ domain
Kelch_1 (PF01344, IPR006652, SM00612): Kelch motif
71 KRTAP10-7interactor100.22226.500Keratin_B2 (PF01500, IPR002494): Keratin, high sulfur B2 protein
PMG (PF05287, IPR007951): PMG protein
DUF4106 (PF13388, IPR025179): Protein of unknown function (DUF4106)
Keratin_B2_2 (PF13885, IPR002494): Keratin, high sulfur B2 protein
72 LDHAL6Binteractor21.0000Ldh_1_C (PF02866, IPR022383): lactate/malate dehydrogenase, alpha/beta C-terminal domain
Ldh_1_N (PF00056, IPR001236): lactate/malate dehydrogenase, NAD binding domain
73 LENG8interactor40.6670.772SAC3_GANP (PF03399, IPR005062): SAC3/GANP family
74 LHX8interactor100LIM (PF00412, IPR001781, SM00132): LIM domain
DUF2175 (PF09943, IPR018686): Uncharacterized protein conserved in archaea (DUF2175)
Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
75 LNX1interactor40.6671.000PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
zf-rbx1 (PF12678, IPR024766): RING-H2 zinc finger domain
zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
76 LOXL4oncoprotein30.6670.105Lysyl_oxidase (PF01186, IPR001695): Lysyl oxidase
SRCR (PF00530, IPR001190): Scavenger receptor cysteine-rich domain
77 LZTS2suppressor80.25015.667CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
DUF1127 (PF06568, IPR009506): Domain of unknown function (DUF1127)
Fez1 (PF06818): Fez1
ADIP (PF11559, IPR021622): Afadin- and alpha -actinin-Binding
DUF4250 (PF14056, IPR025346): Domain of unknown function (DUF4250)
78 MALT1oncoprotein40.6670.105Peptidase_C14 (PF00656, IPR011600): Caspase domain
V-set (PF07686, IPR013106): Immunoglobulin V-set domain
Ig_2 (PF13895, IPR007110): Immunoglobulin domain
Ig_3 (PF13927): Immunoglobulin domain
79 MBD1interactor60.5334.222MBD (PF01429, IPR001739, SM00391): Methyl-CpG binding domain
zf-CXXC (PF02008, IPR002857): CXXC zinc finger domain
80 MBD4suppressor50.8000.536HhH-GPD (PF00730, IPR003265): HhH-GPD superfamily base excision DNA repair protein
MBD (PF01429, IPR001739, SM00391): Methyl-CpG binding domain
81 MCRS1interactor40.5001.019FHA (PF00498, IPR000253, SM00240): FHA domain
MCRS_N (PF13325, IPR025999): N-terminal region of micro-spherule protein
82 MDM2oncoprotein160.26752.024Pinin_SDK_N (PF04697, IPR006787): pinin/SDK conserved region
Presenilin (PF01080, IPR001108): Presenilin
SWIB (PF02201, IPR003121, SM00151): SWIB/MDM2 domain
zf-FPG_IleRS (PF06827, IPR010663): Zinc finger found in FPG and IleRS
zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others
zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
83 MECOMoncoprotein50.7000.658SET (PF00856, IPR001214, SM00317): SET domain
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2H2_6 (PF13912, IPR007087): C2H2-type zinc finger
84 MECP2interactor70.6672.863K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain
MBD (PF01429, IPR001739, SM00391): Methyl-CpG binding domain
SelP_N (PF04592, IPR007671): Selenoprotein P, N terminal region
IHABP4_N (PF16174, IPR032381): Intracellular hyaluronan-binding protein 4 N-terminal
85 MSANTD3interactor100RecU (PF03838, IPR004612): Recombination protein U
Myb_DNA-bind_5 (PF13873, IPR028002): Myb/SANT-like DNA-binding domain
86 MTF2interactor60.5334.239PHD (PF00628, IPR019787, SM00249): PHD-finger
FYVE_2 (PF02318, IPR010911): FYVE-type zinc finger
Mtf2_C (PF14061, IPR025894): Polycomb-like MTF2 factor 2
DUF4537 (PF15057, IPR032770): Domain of unknown function (DUF4537)
87 MTO1interactor21.0000GIDA (PF01134, IPR002218): Glucose inhibited division protein A
GIDA_assoc (PF13932, IPR026904): GidA associated domain
88 MYConcoprotein210.27497.935HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
Myc-LZ (PF02344, IPR003327): Myc leucine zipper domain
Myc_N (PF01056, IPR012682): Myc amino-terminal region
89 MYOD1oncoprotein120.43617.991Basic (PF01586, IPR002546, SM00520): Myogenic Basic domain
HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
Mfp-3 (PF04202, IPR007328): Foot protein 3
Myf5 (PF12232, IPR022032): Myogenic determination factor 5
90 NFATC2suppressor200RHD_DNA_bind (PF00554, IPR011539): Rel homology DNA-binding domain
RHD_dimer (PF16179, IPR032397): Rel homology dimerisation domain
91 NR1H2oncoprotein50.7000.867zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains)
Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
92 NR1H3interactor40.8330.200zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains)
Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
93 OPA3protein found in more fusions40.6670.105IL11 (PF07400, IPR020438): Interleukin 11
OPA3 (PF07047, IPR010754): Optic atrophy 3 protein (OPA3)
94 PHF19interactor71.0000PHD (PF00628, IPR019787, SM00249): PHD-finger
Mtf2_C (PF14061, IPR025894): Polycomb-like MTF2 factor 2
DUF4537 (PF15057, IPR032770): Domain of unknown function (DUF4537)
95 PNKPinteractor30.6670.667PNK3P (PF08645, IPR013954): Polynucleotide kinase 3 phosphatase
AAA_33 (PF13671): AAA domain
96 PRAM1interactor40.8330.500hSH3 (PF14603, IPR029294): Helically-extended SH3 domain
97 PRIM2interactor30.6671.000DNA_primase_lrg (PF04104, IPR007238): Eukaryotic and archaeal DNA primase, large subunit
98 PRMT6interactor260.077248.333Methyltransf_25 (PF13649): Methyltransferase domain
99 PSMC1interactor30.6670.286AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA)
AAA_3 (PF07726, IPR011703): ATPase family associated with various cellular activities (AAA)
DivIC (PF04977, IPR007060): Septum formation initiator
DUF815 (PF05673, IPR008533): Protein of unknown function (DUF815)
Prot_ATP_ID_OB (PF16450, IPR032501): Proteasomal ATPase OB/ID domain
100 PTENsuppressor50.5003.500DSPc (PF00782, IPR020422, SM00195): Dual specificity phosphatase, catalytic domain
PTEN_C2 (PF10409, IPR014020): C2 domain of PTEN tumour-suppressor protein
101 RARAoncoprotein130.40920.325zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains)
Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
102 RASSF1suppressor60.5003.571RA (PF00788, IPR000159, SM00314): Ras association (RalGDS/AF-6) domain
C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain)
Nore1-SARAH (PF16517, IPR011524): Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain
103 RASSF2suppressor40.5001.605RA (PF00788, IPR000159, SM00314): Ras association (RalGDS/AF-6) domain
Nore1-SARAH (PF16517, IPR011524): Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain
104 RB1suppressor200.36360.374RB_A (PF01858, IPR002720): Retinoblastoma-associated protein A domain
RB_B (PF01857, IPR002719): Retinoblastoma-associated protein B domain
Rb_C (PF08934, IPR015030): Rb C-terminal domain
DUF3452 (PF11934, IPR024599): Domain of unknown function (DUF3452)
DUF4592 (PF15262, IPR028030): Domain of unknown function (DUF4592)
105 RBBP4oncoprotein200.47443.795eIF2A (PF08662, IPR013979): Eukaryotic translation initiation factor eIF2A
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Capsid_NCLDV (PF04451, IPR007542): Large eukaryotic DNA virus major capsid protein
CAF1C_H4-bd (PF12265, IPR022052): Histone-binding protein RBBP4 or subunit C of CAF1 complex
106 RBBP7suppressor160.54222.920WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Capsid_NCLDV (PF04451, IPR007542): Large eukaryotic DNA virus major capsid protein
CAF1C_H4-bd (PF12265, IPR022052): Histone-binding protein RBBP4 or subunit C of CAF1 complex
107 RBL1suppressor80.5365.776RB_A (PF01858, IPR002720): Retinoblastoma-associated protein A domain
RB_B (PF01857, IPR002719): Retinoblastoma-associated protein B domain
Rb_C (PF08934, IPR015030): Rb C-terminal domain
DUF3452 (PF11934, IPR024599): Domain of unknown function (DUF3452)
108 RBL2suppressor60.6672.033CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
Pap_E4 (PF02711, IPR003861): E4 protein
RB_A (PF01858, IPR002720): Retinoblastoma-associated protein A domain
RB_B (PF01857, IPR002719): Retinoblastoma-associated protein B domain
SLH (PF00395, IPR001119): S-layer homology domain
TFIIB (PF00382, IPR013150): Transcription factor TFIIB repeat
DUF3452 (PF11934, IPR024599): Domain of unknown function (DUF3452)
109 RIN3interactor60.3335.667RA (PF00788, IPR000159, SM00314): Ras association (RalGDS/AF-6) domain
RNA_pol_Rpb4 (PF03874, IPR005574): RNA polymerase Rpb4
SH2 (PF00017, IPR000980, SM00252): SH2 domain
VPS9 (PF02204, IPR003123, SM00167): Vacuolar sorting protein 9 (VPS9) domain
110 RRP8interactor21.0000eIF3_subunit (PF08597, IPR013906): Translation initiation factor eIF3 subunit
Methyltransf_8 (PF05148, IPR007823): Hypothetical methyltransferase
111 RSPO2oncoprotein21.0000VSP (PF03302, IPR005127): Giardia variant-specific surface protein
Furin-like_2 (PF15913, IPR006212): Furin-like repeat, cysteine-rich
112 RUNX1suppressor120.49112.217Runt (PF00853, IPR013524): Runt domain
RunxI (PF08504, IPR013711): Runx inhibition domain
DUF3037 (PF11236, IPR021398): Protein of unknown function (DUF3037)
113 RUNX2suppressor80.6434.148DUF1180 (PF06679, IPR009565): Protein of unknown function (DUF1180)
Runt (PF00853, IPR013524): Runt domain
TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360)
DUF2722 (PF10846, IPR021216): Protein of unknown function (DUF2722)
114 RUNX3suppressor70.6672.983Runt (PF00853, IPR013524): Runt domain
RunxI (PF08504, IPR013711): Runx inhibition domain
115 RUVBL2oncoprotein110.46715.888TIP49 (PF06068, IPR010339): TIP49 C-terminus
116 S100A4interactor50.4004.167S_100 (PF01023, IPR013787): S-100/ICaBP type calcium binding domain
EF-hand_4 (PF12763, IPR000261): Cytoskeletal-regulatory complex EF hand
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
117 SBF1interactor100dDENN (PF03455, IPR005112, SM00801): dDENN domain
DENN (PF02141, IPR001194, SM00799): DENN (AEX-3) domain
GRAM (PF02893, IPR004182, SM00568): GRAM domain
Myotub-related (PF06602, IPR010569): Myotubularin-like phosphatase domain
PH (PF00169, IPR001849, SM00233): PH domain
uDENN (PF03456, IPR005113, SM00800): uDENN domain
T2SSJ (PF11612, IPR010055): Type II secretion system (T2SS), protein J
SBF2 (PF12335, IPR022096): Myotubularin protein
118 SIRT1suppressor190.30762.366DUF592 (PF04574, IPR007654): Protein of unknown function (DUF592)
SIR2 (PF02146, IPR003000): Sir2 family
TPP_enzyme_M (PF00205, IPR012000): Thiamine pyrophosphate enzyme, central domain
119 SLFN12interactor100AlbA_2 (PF04326, IPR007421): Putative DNA-binding domain
B3R (PF17057, IPR031450): Poxviridae B3 protein
120 SMAD3oncoprotein170.35847.206MH1 (PF03165, IPR003619, SM00523): MH1 domain
MH2 (PF03166, IPR001132, SM00524): MH2 domain
121 SMAD5interactor70.6195.967MH1 (PF03165, IPR003619, SM00523): MH1 domain
MH2 (PF03166, IPR001132, SM00524): MH2 domain
122 SPATA24interactor30.6670.286SPATA24 (PF15175, IPR029176): Spermatogenesis-associated protein 24
123 SPRED1interactor100SMC_ScpA (PF02616, IPR003768): Segregation and condensation protein ScpA
Sprouty (PF05210, IPR007875): Sprouty protein (Spry)
WH1 (PF00568, IPR000697, SM00461): WH1 domain
124 SPSB1interactor30.6670.105SPRY (PF00622, IPR003877, SM00449): SPRY domain
SOCS_box (PF07525, IPR001496): SOCS box
125 SRGAP3suppressor30.6670.105CENP-H (PF05837, IPR008426): Centromere protein H (CENP-H)
Med9 (PF07544, IPR011425): RNA polymerase II transcription mediator complex subunit 9
DUF16 (PF01519, IPR002862): Protein of unknown function DUF16
FCH (PF00611, IPR001060, SM00055): Fes/CIP4, and EFC/F-BAR homology domain
FlaC_arch (PF05377, IPR008039): Flagella accessory protein C (FlaC)
RhoGAP (PF00620, IPR000198, SM00324): RhoGAP domain
TMPIT (PF07851, IPR012926): TMPIT-like protein
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
DUF4164 (PF13747, IPR025310): Domain of unknown function (DUF4164)
126 STX11interactor40.6670.400KxDL (PF10241, IPR019371): Uncharacterized conserved protein
Syntaxin (PF00804, IPR006011, SM00503): Syntaxin
SNARE (PF05739, IPR000727, SM00397): SNARE domain
127 STX19interactor21.0000DUF16 (PF01519, IPR002862): Protein of unknown function DUF16
Syntaxin (PF00804, IPR006011, SM00503): Syntaxin
SNARE (PF05739, IPR000727, SM00397): SNARE domain
128 TAL1oncoprotein80.8571.036HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
SelK_SelG (PF10961, IPR024491): Selenoprotein SelK_SelG
129 TEX35interactor30.6670.105Tsc35 (PF15079, IPR027874): Testis-specific protein 35
130 THRAsuppressor40.6670.400C1_2 (PF03107, IPR004146): C1 domain
zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains)
Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
131 TMEM11interactor100Mito_morph_reg (PF14972, IPR026120): Mitochondrial morphogenesis regulator
132 TNFAIP1oncoprotein40.6670.333BTB_2 (PF02214, IPR003131): BTB/POZ domain
133 TNS2interactor60.3339.333PTB (PF08416, IPR013625): Phosphotyrosine-binding domain
SH2 (PF00017, IPR000980, SM00252): SH2 domain
PTEN_C2 (PF10409, IPR014020): C2 domain of PTEN tumour-suppressor protein
C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain)
cEGF (PF12662, IPR026823): Complement Clr-like EGF-like
PRIMA1 (PF16101): Proline-rich membrane anchor 1
134 U2AF1oncoprotein21.0000DUF1509 (PF07420, IPR010883): Protein of unknown function (DUF1509)
KMP11 (PF03037, IPR004132): Kinetoplastid membrane protein 11
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
zf-CCCH (PF00642, IPR000571): Zinc finger C-x8-C-x5-C-x3-H type (and similar)
135 UHRF1interactor110.6008.777PHD (PF00628, IPR019787, SM00249): PHD-finger
SAD_SRA (PF02182, IPR003105, SM00466): SAD/SRA domain
zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
TTD (PF12148, IPR021991): Tandem tudor domain within UHRF1
zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
zf-RING_10 (PF16685, IPR032043): zinc RING finger of MSL2
136 WDFY3interactor50.4005.333Beach (PF02138, IPR000409, SM01026): Beige/BEACH domain
FYVE (PF01363, IPR000306, SM00064): FYVE zinc finger
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Laminin_G_3 (PF13385): Concanavalin A-like lectin/glucanases superfamily
E3_UbLigase_R4 (PF13764, IPR025704): E3 ubiquitin-protein ligase UBR4
PH_BEACH (PF14844, IPR023362): PH domain associated with Beige/BEACH
DUF4704 (PF15787, IPR031570): Domain of unknown function (DUF4704)
DUF4800 (PF16057): Domain of unknown function (DUF4800)
137 WIZinteractor40.5001.182AnfO_nitrog (PF09582, IPR014287): Iron only nitrogenase protein AnfO (AnfO_nitrog)
C1_2 (PF03107, IPR004146): C1 domain
Zn-ribbon_8 (PF09723, IPR013429, SM00834): Zinc ribbon domain
Enterotoxin_ST (PF02048, IPR001489): Heat-stable enterotoxin ST
zf-C2H2_4 (PF13894): C2H2-type zinc finger
138 ZBTB24interactor60.4007.500AT_hook (PF02178, IPR017956, SM00384): AT hook motif
BTB (PF00651, IPR013069, SM00225): BTB/POZ domain
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zinc_ribbon_4 (PF13717): zinc-ribbon domain
139 ZCCHC17interactor21.0000S1 (PF00575, IPR003029, SM00316): S1 RNA binding domain
SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein
Coilin_N (PF15862, IPR031722): Coilin N-terminus
140 ZKSCAN5interactor100FerB (PF08150, IPR012561): FerB (NUC096) domain
KRAB (PF01352, IPR001909, SM00349): KRAB box
SCAN (PF02023, IPR003309, SM00431): SCAN domain
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2H2_11 (PF16622, IPR007087): zinc-finger C2H2-type
141 ZNF165interactor30.6671.000SCAN (PF02023, IPR003309, SM00431): SCAN domain
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
142 ZNF436interactor30.6670.105KRAB (PF01352, IPR001909, SM00349): KRAB box
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
143 ZNF451protein found in more fusions41.0000zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
EPL1 (PF10513, IPR019542): Enhancer of polycomb-like
zf-C2H2_jaz (PF12171, IPR022755): Zinc-finger double-stranded RNA-binding
zf-C2H2_2 (PF12756, IPR015880): C2H2 type zinc-finger (2 copies)
zf-met (PF12874): Zinc-finger of C2H2 type
zf-C2H2_4 (PF13894): C2H2-type zinc finger
Cys_rich_KTR (PF14205, IPR025957): Cysteine-rich KTR
FOXP-CC (PF16159, IPR032354): FOXP coiled-coil domain
144 ZNF557interactor30.6670.667KRAB (PF01352, IPR001909, SM00349): KRAB box
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
145 ZNF581interactor50.4004.452zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger
146 ZNF649interactor21.0000KRAB (PF01352, IPR001909, SM00349): KRAB box
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
147 ZNF670interactor21.0000KRAB (PF01352, IPR001909, SM00349): KRAB box
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger
148 ZNF829interactor30.6670.286KRAB (PF01352, IPR001909, SM00349): KRAB box
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
149 ZSCAN9interactor21.0000SCAN (PF02023, IPR003309, SM00431): SCAN domain
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-ribbon_3 (PF13248): zinc-ribbon domain
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain

B a c k    t o    T o p ⇑