Find Fusion Network

Enter
Fusion ID:
Protein names:


Level of PPIs:
or Upload text file:
Update repository
Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

Powered by Cytoscape Web for: parental proteins STUB1 (from a repository: Sun Dec 4 04:13:11 2016)
Examples

Cytoscape Web will replace the contents your graph
PPI Properties:

Click on nodes
or edges

Layout Tree
Circle
Radial
Force Directed
Preset
Export graph
PDF file
SVG file
SIF file
XML file
GraphML file

Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)239
The number (and %) of the onco-proteins76 (31.80 %)
The number (and %) of the tumor suppressors38 (15.90 %)
Total number of binary PPIs (saturation %)1899 (6.68 %)
The number (and %) of affected PPIs239 (12.59 %)
The number of possible different fusions50
PPI diameter2
PPI radius1
The average degree of PPI14.996
Assortativity coefficient-0.2117
The network average Clustering coefficient0.509
The number (and %) of a zero Clustering coefficients7 (2.93 %)
The number (and %) of a zero Betweenness Centrality35 (14.64 %)

ACTIVE INTERACTORS


List of the fusions

Proteins found in more fusions SMAD4 (see 2 fusions); MAP3K2 (see 2 fusions); PRPF19 (see 2 fusions); HSF1 (see 3 fusions); CTBP2 (see 2 fusions); UBE2N (see 1 fusions); VHL (see 1 fusions); MYC (see 1 fusions); RUNX1 (see 1 fusions); UBE2D2 (see 2 fusions); AHCYL1 (see 3 fusions); UBE2E2 (see 1 fusions); AIMP2 (see 1 fusions); MAP3K5 (see 1 fusions); UBE2E1 (see 2 fusions); UBC (see 1 fusions); LRRK2 (see 1 fusions); TP53 (see 3 fusions); TRAF6 (see 1 fusions); BCR/ABL1 (see 183 fusions); ILK (see 1 fusions); APP (see 4 fusions); TPM1 (see 2 fusions); AHR (see 1 fusions); VCP (see 4 fusions); FOXO1 (see 1 fusions); HSP90AA1 (see 2 fusions); PRMT5 (see 2 fusions); NR3C1 (see 8 fusions); ATXN1 (see 3 fusions); HSP90AB1 (see 1 fusions); SQSTM1 (see 5 fusions); SGK1 (see 2 fusions); MAPT (see 1 fusions); BAG2 (see 1 fusions); ENO1/CCT7 (see 1 fusions); MALT1 (see 1 fusions); KHDRBS1 (see 1 fusions); BAG3 (see 4 fusions); EGFR (see 2 fusions); STUB1 (see 1 fusions); HSPB1 (see 4 fusions); NQO1 (see 2 fusions); MAP3K7 (see 7 fusions); PTK2 (see 2 fusions); EPAS1 (see 1 fusions); CDC37 (see 2 fusions); SMAD3 (see 3 fusions); HSPA8/HSPD1 (see 1 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 STUB1parental protein2390.05535206.287U-box (PF04564, IPR003613, SM00504): U-box domain
ANAPC3 (PF12895): Anaphase-promoting complex, cyclosome, subunit 3
TPR_11 (PF13414, IPR011990): TPR repeat
TPR_20 (PF14561): Tetratricopeptide repeat
2 ABL1oncoprotein200.45630.449Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
SH2 (PF00017, IPR000980, SM00252): SH2 domain
F_actin_bind (PF08919, IPR015015, SM00808): F-actin binding
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
FRG2 (PF15315, IPR026245): Facioscapulohumeral muscular dystrophy candidate 2
3 ACDinteractor80.8571.057TPP1 (PF10341, IPR019437): Shelterin complex subunit, TPP1/ACD
4 AGO1interactor100.4229.558ArgoL1 (PF08699, IPR014811, SM01163): Argonaute linker 1 domain
PAZ (PF02170, IPR003100, SM00949): PAZ domain
Piwi (PF02171, IPR003165, SM00950): Piwi domain
ArgoN (PF16486, IPR032474): N-terminal domain of argonaute
ArgoMid (PF16487, IPR032473): Mid domain of argonaute
ArgoL2 (PF16488, IPR032472): Argonaute linker 2 domain
5 AHCYL1suppressor220.229103.347AdoHcyase (PF05221, IPR000043, SM00996): S-adenosyl-L-homocysteine hydrolase
AdoHcyase_NAD (PF00670, IPR015878, SM00997): S-adenosyl-L-homocysteine hydrolase, NAD binding domain
DUF515 (PF04415, IPR007509): Protein of unknown function (DUF515)
Big_3_5 (PF16640, IPR032109): Bacterial Ig-like domain (group 3)
6 AHRsuppressor70.8000.511HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
PAS (PF00989, IPR013767, SM00091): PAS fold
PAS_3 (PF08447, IPR013655): PAS fold
PAS_4 (PF08448, IPR013656): PAS fold
7 AIMP2suppressor110.4895.361GST_C_2 (PF13410): Glutathione S-transferase, C-terminal domain
GST_C_3 (PF14497, IPR004046): Glutathione S-transferase, C-terminal domain
AIMP2_LysRS_bd (PF16780, IPR031889): AIMP2 lysyl-tRNA synthetase binding domain
8 AKT1oncoprotein420.294260.020PH (PF00169, IPR001849, SM00233): PH domain
Pkinase (PF00069, IPR000719): Protein kinase domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
9 AMBRA1interactor160.49218.551Acyl_CoA_thio (PF02551, IPR025652): Acyl-CoA thioesterase
eIF2A (PF08662, IPR013979): Eukaryotic translation initiation factor eIF2A
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Spt20 (PF12090, IPR021950): Spt20 family
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
10 APPprotein found in more fusions500.137695.970APP_N (PF02177, IPR015849, SM00006): Amyloid A4 N-terminal heparin-binding
Beta-APP (PF03494, IPR013803): Beta-amyloid peptide (beta-APP)
BUD22 (PF09073, IPR015158): BUD22
IncA (PF04156, IPR007285): IncA protein
Kunitz_BPTI (PF00014, IPR002223, SM00131): Kunitz/Bovine pancreatic trypsin inhibitor domain
APP_amyloid (PF10515, IPR019543): beta-amyloid precursor protein C-terminus
APP_Cu_bd (PF12924, IPR011178): Copper-binding of amyloid precursor, CuBD
APP_E2 (PF12925, IPR024329): E2 domain of amyloid precursor protein
11 ARoncoprotein260.33385.663Androgen_recep (PF02166, IPR001103): Androgen receptor
zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains)
Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
12 ARAFoncoprotein70.4765.908Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
RBD (PF02196, IPR003116, SM00455): Raf-like Ras-binding domain
C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain)
13 ARRB1interactor190.40948.212Arrestin_C (PF02752, IPR011022, SM01017): Arrestin (or S-antigen), C-terminal domain
Arrestin_N (PF00339, IPR011021): Arrestin (or S-antigen), N-terminal domain
14 ARRB2interactor240.35179.343Arrestin_C (PF02752, IPR011022, SM01017): Arrestin (or S-antigen), C-terminal domain
Arrestin_N (PF00339, IPR011021): Arrestin (or S-antigen), N-terminal domain
15 ASB10interactor40.6670.238Ank (PF00023, IPR002110, SM00248): Ankyrin repeat
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
Ank_4 (PF13637): Ankyrin repeats (many copies)
SOCS_box (PF07525, IPR001496): SOCS box
16 ASB4interactor50.5001.520Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
Ank_4 (PF13637): Ankyrin repeats (many copies)
Ank_5 (PF13857): Ankyrin repeats (many copies)
SOCS_box (PF07525, IPR001496): SOCS box
17 ATCAYinteractor21.0000BNIP2 (PF12496, IPR022181): Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2
CRAL_TRIO_2 (PF13716, IPR001251): Divergent CRAL/TRIO domain
18 ATP6AP2interactor50.5001.917Phosphodiest (PF01663, IPR002591): Type I phosphodiesterase / nucleotide pyrophosphatase
Renin_r (PF07850, IPR012493): Renin receptor-like protein
19 ATXN1protein found in more fusions100.4178.994AXH (PF08517, IPR013723, SM00536): Ataxin-1 and HBP1 module (AXH)
Spt20 (PF12090, IPR021950): Spt20 family
ATXN-1_C (PF12547, IPR020997): Capicua transcriptional repressor modulator
Cnd1_N (PF12922, IPR024324): non-SMC mitotic condensation complex subunit 1, N-term
20 ATXN3interactor130.5159.772Josephin (PF02099, IPR006155): Josephin
UIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif
SUIM_assoc (PF16619): Unstructured region C-term to UIM in Ataxin3
21 AVPR2interactor31.00007tm_1 (PF00001, IPR000276): 7 transmembrane receptor (rhodopsin family)
22 AXLoncoprotein40.8330.182fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
DUF2627 (PF11118, IPR020138): Protein of unknown function (DUF2627)
Ig_2 (PF13895, IPR007110): Immunoglobulin domain
Ig_3 (PF13927): Immunoglobulin domain
23 BACE1interactor60.4006.472Asp (PF00026, IPR001461): Eukaryotic aspartyl protease
24 BAG1oncoprotein220.35146.926BAG (PF02179, IPR003103, SM00264): BAG domain
Presenilin (PF01080, IPR001108): Presenilin
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
DUF5082 (PF16888, IPR031681): Domain of unknown function (DUF5082)
25 BAG2protein found in more fusions320.295172.295IncA (PF04156, IPR007285): IncA protein
Mnd1 (PF03962, IPR005647): Mnd1 family
ParD_antitoxin (PF03693, IPR022789): Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH
26 BAG3oncoprotein390.219324.269BAG (PF02179, IPR003103, SM00264): BAG domain
WW (PF00397, IPR001202, SM00456): WW domain
27 BAG4interactor130.46213.078BAG (PF02179, IPR003103, SM00264): BAG domain
DMP12 (PF16779, IPR031891): DNA-mimic protein
28 BAG5interactor90.4449.599BAG (PF02179, IPR003103, SM00264): BAG domain
PDGF_N (PF04692, IPR006782): Platelet-derived growth factor, N terminal region
RRF (PF01765, IPR023584): Ribosome recycling factor
29 BCRsuppressor120.6673.846Bcr-Abl_Oligo (PF09036, IPR015123): Bcr-Abl oncoprotein oligomerisation domain
C2 (PF00168, IPR000008, SM00239): C2 domain
PH (PF00169, IPR001849, SM00233): PH domain
RhoGAP (PF00620, IPR000198, SM00324): RhoGAP domain
RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain
IQ_SEC7_PH (PF16453, IPR001849): PH domain
30 CARD11oncoprotein70.7331.400CARD (PF00619, IPR001315, SM00114): Caspase recruitment domain
DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664)
Cnn_1N (PF07989, IPR012943): Centrosomin N-terminal motif 1
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
zf-C4H2 (PF10146, IPR018482): Zinc finger-containing protein
Guanylate_kin (PF00625, IPR008145, SM00072): Guanylate kinase
DUF3450 (PF11932, IPR016866): Protein of unknown function (DUF3450)
31 CCL28interactor21.0000IL8 (PF00048, IPR001811, SM00199): Small cytokines (intecrine/chemokine), interleukin-8 like
32 CCT5interactor170.30135.250Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
33 CCT7protein found in more fusions180.34632.164Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
34 CD4suppressor90.6433.238ATP1G1_PLM_MAT8 (PF02038, IPR000272): ATP1G1/PLM/MAT8 family
C2-set (PF05790, IPR008424): Immunoglobulin C2-set domain
CD4-extracel (PF09191, IPR015274): CD4, extracellular
ig (PF00047, IPR013151, SM00409): Immunoglobulin domain
Tcell_CD4_C (PF12104, IPR021963): T cell CD4 receptor C terminal region
35 CDC37protein found in more fusions390.248260.297CDC37_C (PF08564, IPR013873, SM01069): Cdc37 C terminal domain
CDC37_M (PF08565, IPR013874, SM01070): Cdc37 Hsp90 binding domain
CDC37_N (PF03234, IPR013855, SM01071): Cdc37 N terminal kinase binding
Rho_Binding (PF08912, IPR015008): Rho Binding
TMF_DNA_bd (PF12329, IPR022092): TATA element modulatory factor 1 DNA binding
36 CDC37L1interactor50.9000.250CDC37_M (PF08565, IPR013874, SM01070): Cdc37 Hsp90 binding domain
37 CDK18oncoprotein60.9330.154APH (PF01636, IPR002575): Phosphotransferase enzyme family
Pkinase (PF00069, IPR000719): Protein kinase domain
38 CDK20oncoprotein40.5000.983Pkinase (PF00069, IPR000719): Protein kinase domain
39 CDK5oncoprotein150.45125.245Pkinase (PF00069, IPR000719): Protein kinase domain
40 CFLARoncoprotein80.4763.188DED (PF01335, IPR001875, SM00031): Death effector domain
Peptidase_C14 (PF00656, IPR011600): Caspase domain
41 CFTRsuppressor230.42042.710ABC_membrane (PF00664, IPR001140): ABC transporter transmembrane region
ABC_tran (PF00005, IPR003439): ABC transporter
Roc (PF08477, IPR013684): Ras of Complex, Roc, domain of DAPkinase
SMC_N (PF02463, IPR003395): RecF/RecN/SMC N terminal domain
Rotamase_2 (PF13145, IPR000297): PPIC-type PPIASE domain
CFTR_R (PF14396, IPR025837): Cystic fibrosis TM conductance regulator (CFTR), regulator domain
42 CHUKsuppressor210.45336.289Pkinase (PF00069, IPR000719): Protein kinase domain
IKKbetaNEMObind (PF12179, IPR022007): I-kappa-kinase-beta NEMO binding domain
43 CTBP2protein found in more fusions80.3818.6052-Hacid_dh_C (PF02826, IPR006140): D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
44 CUL4Boncoprotein170.50722.007Cullin (PF00888, IPR001373, SM00182): Cullin family
EBP50_C (PF09007, IPR015098): EBP50, C-terminal
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
PG_binding_4 (PF12229, IPR022029): Putative peptidoglycan binding domain
MDFI (PF15316, IPR026134): MyoD family inhibitor
45 CYP2E1interactor100p450 (PF00067, IPR001128): Cytochrome P450
46 CYP3A4interactor40.6670.200p450 (PF00067, IPR001128): Cytochrome P450
47 DAXXoncoprotein140.32122.560Daxx (PF03344, IPR005012): Daxx N-terminal Rassf1C-interacting domain
Merozoite_SPAM (PF07133, IPR010784): Merozoite surface protein (SPAM)
Nop14 (PF04147, IPR007276): Nop14-like family
RF-1 (PF00472, IPR000352): RF-1 domain
Vpu (PF00558, IPR008187): Vpu protein
DUF3391 (PF11871, IPR021812): Domain of unknown function (DUF3391)
48 DNAJA3suppressor140.42920.298DnaJ (PF00226, IPR001623, SM00271): DnaJ domain
DnaJ_C (PF01556, IPR002939): DnaJ C terminal domain
49 DNAJB1suppressor280.325102.775DnaJ (PF00226, IPR001623, SM00271): DnaJ domain
DnaJ_C (PF01556, IPR002939): DnaJ C terminal domain
50 DNAJB6interactor130.5139.075DnaJ (PF00226, IPR001623, SM00271): DnaJ domain
51 DNAJC13interactor30.6670.250Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
DnaJ (PF00226, IPR001623, SM00271): DnaJ domain
Arm_2 (PF04826, IPR006911): Armadillo-like
DUF4339 (PF14237, IPR025640): Domain of unknown function (DUF4339)
52 DNAJC5interactor31.0000DnaJ (PF00226, IPR001623, SM00271): DnaJ domain
Baculo_F (PF12259, IPR022048): Baculovirus F protein
53 DNAJC7interactor260.37299.566DnaJ (PF00226, IPR001623, SM00271): DnaJ domain
TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat
Rapsyn_N (PF10579, IPR019568): Rapsyn N-terminal myristoylation and linker region
ANAPC3 (PF12895): Anaphase-promoting complex, cyclosome, subunit 3
TPR_11 (PF13414, IPR011990): TPR repeat
TPR_17 (PF13431): Tetratricopeptide repeat
54 DPM1interactor50.4001.951Glycos_transf_2 (PF00535, IPR001173): Glycosyl transferase family 2
55 DRD4interactor31.00007tm_1 (PF00001, IPR000276): 7 transmembrane receptor (rhodopsin family)
7TM_GPCR_Srx (PF10328, IPR019430): Serpentine type 7TM GPCR chemoreceptor Srx
56 DYRK1Boncoprotein50.6671.167Pkinase (PF00069, IPR000719): Protein kinase domain
57 DYX1C1interactor21.0000CS (PF04969, IPR007052): CS domain
Presenilin (PF01080, IPR001108): Presenilin
TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
DUF3035 (PF11233, IPR021395): Protein of unknown function (DUF3035)
TPR_11 (PF13414, IPR011990): TPR repeat
G0-G1_switch_2 (PF15103, IPR016821): G0/G1 switch protein 2
CCDC66 (PF15236): Coiled-coil domain-containing protein 66
58 EGFRoncoprotein500.255445.627Furin-like (PF00757, IPR006211): Furin-like cysteine rich region
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
Recep_L_domain (PF01030, IPR000494): Receptor L domain
GAPT (PF11770, IPR021082): GRB2-binding adapter (GAPT)
GF_recep_IV (PF14843, IPR032778): Growth factor receptor domain IV
59 EIF4Eoncoprotein31.0000IF4E (PF01652, IPR001040): Eukaryotic initiation factor 4E
60 EIF5Ainteractor60.5331.995EFP_N (PF08207, IPR013185): Elongation factor P (EF-P) KOW-like domain
eIF-5a (PF01287, IPR020189): Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold
61 ENDOGinteractor30.6670.250Pyr_redox_2 (PF07992, IPR023753): Pyridine nucleotide-disulphide oxidoreductase
62 ENO1oncoprotein150.18152.146Enolase_C (PF00113, IPR020810): Enolase, C-terminal TIM barrel domain
Enolase_N (PF03952, IPR020811): Enolase, N-terminal domain
63 EPAS1suppressor120.50910.942Corona_I (PF03187, IPR004876): Corona nucleocapsid I protein
HIF-1a_CTAD (PF08778, IPR014887): HIF-1 alpha C terminal transactivation domain
HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
PAS (PF00989, IPR013767, SM00091): PAS fold
HIF-1 (PF11413, IPR021537): Hypoxia-inducible factor-1
PAS_11 (PF14598): PAS domain
64 EPM2Ainteractor60.6001.425CBM_20 (PF00686, IPR002044): Starch binding domain
DSPc (PF00782, IPR020422, SM00195): Dual specificity phosphatase, catalytic domain
65 ERBB2oncoprotein130.57611.525Furin-like (PF00757, IPR006211): Furin-like cysteine rich region
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
Recep_L_domain (PF01030, IPR000494): Receptor L domain
GF_recep_IV (PF14843, IPR032778): Growth factor receptor domain IV
66 ERN1interactor100.5563.985Pkinase (PF00069, IPR000719): Protein kinase domain
PQQ (PF01011, IPR002372, SM00564): PQQ enzyme repeat
Ribonuc_2-5A (PF06479, IPR010513): Ribonuclease 2-5A
CytochromB561_N (PF09786, IPR019176): Cytochrome B561, N terminal
PQQ_2 (PF13360, IPR002372): PQQ-like domain
67 ESR1suppressor410.241336.791Oest_recep (PF02159, IPR001292): Oestrogen receptor
zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains)
Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
ESR1_C (PF12743, IPR024736): Oestrogen-type nuclear receptor final C-terminal
68 EVC2interactor70.3818.187HBS1_N (PF08938, IPR015033): HBS1 N-terminus
DUF342 (PF03961, IPR005646): Protein of unknown function (DUF342)
Histone_HNS (PF00816, IPR001801): H-NS histone family
EVC2_like (PF12297, IPR022076): Ellis van Creveld protein 2 like protein
69 FBXO2interactor80.3219.410FBA (PF04300, IPR007397): F-box associated region
F-box (PF00646, IPR001810, SM00256): F-box domain
70 FBXO27interactor21.0000FBA (PF04300, IPR007397): F-box associated region
F-box (PF00646, IPR001810, SM00256): F-box domain
71 FMR1interactor50.5000.611Agenet (PF05641, IPR008395, SM00743): Agenet domain
KH_1 (PF00013, IPR004088, SM00322): KH domain
FXMRP1_C_core (PF12235, IPR022034): Fragile X-related 1 protein core C terminal
FXMR_C2 (PF16098, IPR032196): Fragile X-related mental retardation protein C-terminal region 2
72 FOXO1suppressor80.8570.625K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain
Forkhead (PF00250, IPR001766, SM00339): Forkhead domain
FOXO_KIX_bdg (PF16675, IPR032068): KIX-binding domain of forkhead box O, CR2
FOXO-TAD (PF16676, IPR032067): Transactivation domain of FOXO protein family
73 FOXP3suppressor40.6671.167Forkhead (PF00250, IPR001766, SM00339): Forkhead domain
FOXP-CC (PF16159, IPR032354): FOXP coiled-coil domain
74 GHRoncoprotein200EpoR_lig-bind (PF09067, IPR015152): Erythropoietin receptor, ligand binding
fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
GHBP (PF12772, IPR025871): Growth hormone receptor binding
75 GPR37interactor70.8100.9947tm_1 (PF00001, IPR000276): 7 transmembrane receptor (rhodopsin family)
76 GUCY1A2oncoprotein40.8330.500HNOB (PF07700, IPR011644): Haem-NO-binding
HNOBA (PF07701, IPR011645): Heme NO binding associated
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
Guanylate_cyc (PF00211, IPR001054, SM00044): Adenylate and Guanylate cyclase catalytic domain
77 GUCY1A3interactor21.0000HNOB (PF07700, IPR011644): Haem-NO-binding
HNOBA (PF07701, IPR011645): Heme NO binding associated
Guanylate_cyc (PF00211, IPR001054, SM00044): Adenylate and Guanylate cyclase catalytic domain
78 GUCY1B3interactor40.8330.5004_1_CTD (PF05902, IPR008379): 4.1 protein C-terminal domain (CTD)
HNOB (PF07700, IPR011644): Haem-NO-binding
HNOBA (PF07701, IPR011645): Heme NO binding associated
Guanylate_cyc (PF00211, IPR001054, SM00044): Adenylate and Guanylate cyclase catalytic domain
79 HDAC6oncoprotein330.274174.306Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
PSGP (PF07276, IPR009900): Apopolysialoglycoprotein (PSGP)
zf-UBP (PF02148, IPR001607, SM00290): Zn-finger in ubiquitin-hydrolases and other protein
80 HIF1Asuppressor250.37070.090Dicty_REP (PF05086, IPR007778): Dictyostelium (Slime Mold) REP protein
HIF-1a_CTAD (PF08778, IPR014887): HIF-1 alpha C terminal transactivation domain
HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
PAS (PF00989, IPR013767, SM00091): PAS fold
PAS_3 (PF08447, IPR013655): PAS fold
HIF-1 (PF11413, IPR021537): Hypoxia-inducible factor-1
81 HSF1protein found in more fusions140.53813.522DUF247 (PF03140, IPR004158): Plant protein of unknown function
Vert_HS_TF (PF06546, IPR010542): Vertebrate heat shock transcription factor
HSF_DNA-bind (PF00447, IPR000232, SM00415): HSF-type DNA-binding
82 HSP90AA1oncoprotein1070.1183244.149HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
HSP90 (PF00183, IPR001404): Hsp90 protein
83 HSP90AB1oncoprotein440.309275.988HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
HSP90 (PF00183, IPR001404): Hsp90 protein
84 HSPA1Ainteractor450.240354.380HSP70 (PF00012, IPR013126): Hsp70 protein
85 HSPA1Binteractor100.4449.924HSP70 (PF00012, IPR013126): Hsp70 protein
86 HSPA1Linteractor220.32952.799HSP70 (PF00012, IPR013126): Hsp70 protein
87 HSPA2interactor180.44424.138HSP70 (PF00012, IPR013126): Hsp70 protein
88 HSPA4interactor810.1531632.206Herpes_ICP4_N (PF03584, IPR005206): Herpesvirus ICP4-like protein N-terminal region
HSP70 (PF00012, IPR013126): Hsp70 protein
TP53IP5 (PF15331, IPR029290): Cellular tumour antigen p53-inducible 5
89 HSPA4Linteractor100.40015.655HSP70 (PF00012, IPR013126): Hsp70 protein
90 HSPA5oncoprotein400.377149.002HSP70 (PF00012, IPR013126): Hsp70 protein
91 HSPA8oncoprotein680.207927.578HSP70 (PF00012, IPR013126): Hsp70 protein
92 HSPB1oncoprotein370.303213.530HSP20 (PF00011, IPR002068): Hsp20/alpha crystallin family
93 HSPBP1interactor90.4728.121Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
Fes1 (PF08609, IPR013918): Nucleotide exchange factor Fes1
Rcd1 (PF04078, IPR007216): Cell differentiation family, Rcd1-like
HEAT_EZ (PF13513): HEAT-like repeat
94 HSPD1suppressor290.333109.801Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
95 ILKsuppressor140.32125.328Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
Ank_4 (PF13637): Ankyrin repeats (many copies)
Ank_5 (PF13857): Ankyrin repeats (many copies)
96 IRAK1interactor240.36472.452Death (PF00531, IPR000488, SM00005): Death domain
Pkinase (PF00069, IPR000719): Protein kinase domain
97 IRF1suppressor31.0000IRF (PF00605, IPR001346, SM00348): Interferon regulatory factor transcription factor
98 JAK3oncoprotein50.5003.400Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
SH2 (PF00017, IPR000980, SM00252): SH2 domain
99 JOSD1interactor21.0000Josephin (PF02099, IPR006155): Josephin
100 JOSD2interactor30.6670.154Josephin (PF02099, IPR006155): Josephin
101 KATNA1interactor50.8000.236AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA)
ABC_tran (PF00005, IPR003439): ABC transporter
Vps4_C (PF09336, IPR015415): Vps4 C terminal oligomerisation domain
TPR_8 (PF13181, IPR019734): Tetratricopeptide repeat
AAA_22 (PF13401, IPR003593): AAA domain
102 KCNA5interactor50.8330.111Ion_trans (PF00520, IPR005821): Ion transport protein
BTB_2 (PF02214, IPR003131): BTB/POZ domain
103 KCNH2interactor51.0000Ion_trans (PF00520, IPR005821): Ion transport protein
cNMP_binding (PF00027, IPR000595, SM00100): Cyclic nucleotide-binding domain
PAS_9 (PF13426, IPR000014): PAS domain
104 KCNQ4interactor31.0000Ion_trans (PF00520, IPR005821): Ion transport protein
KCNQ_channel (PF03520, IPR013821): KCNQ voltage-gated potassium channel
105 KHDRBS1protein found in more fusions80.3817.298KH_1 (PF00013, IPR004088, SM00322): KH domain
Qua1 (PF16274, IPR032571): Qua1 domain
Sam68-YY (PF16568, IPR032335): Tyrosine-rich domain of Sam68
106 KIAA0753interactor40.6670.515MNR (PF15718, IPR031447): Protein moonraker
107 KIAA1524oncoprotein60.4671.459Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16)
CBF (PF03914, IPR005612, SM00521): CBF/Mak21 family
DUF724 (PF05266, IPR007930): Protein of unknown function (DUF724)
ParcG (PF10274, IPR019399): Parkin co-regulated protein
ADIP (PF11559, IPR021622): Afadin- and alpha -actinin-Binding
DUF3450 (PF11932, IPR016866): Protein of unknown function (DUF3450)
108 KLHL29interactor21.0000BACK (PF07707, IPR011705, SM00875): BTB And C-terminal Kelch
BTB (PF00651, IPR013069, SM00225): BTB/POZ domain
Kelch_1 (PF01344, IPR006652, SM00612): Kelch motif
Kelch_5 (PF13854): Kelch motif
Kelch_6 (PF13964): Kelch motif
109 LIMS1interactor40.5001.733LIM (PF00412, IPR001781, SM00132): LIM domain
TNFR_c6 (PF00020, IPR001368, SM00208): TNFR/NGFR cysteine-rich region
zf-RRN7 (PF11781, IPR021752): Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7
110 LLGL2interactor70.4003.987Lgl_C (PF08596, IPR013905): Lethal giant larvae(Lgl) like, C-terminal
LLGL (PF08366, IPR013577): LLGL2
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
RAB3GAP2_N (PF14655, IPR032839): Rab3 GTPase-activating protein regulatory subunit N-terminus
111 LRRK2oncoprotein180.44925.536Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
ATP-synt_ab (PF00006, IPR000194): ATP synthase alpha/beta family, nucleotide-binding domain
DUF1043 (PF06295, IPR009386): Protein of unknown function (DUF1043)
T2SSE (PF00437, IPR001482): Type II/IV secretion system protein
Roc (PF08477, IPR013684): Ras of Complex, Roc, domain of DAPkinase
Pkinase (PF00069, IPR000719): Protein kinase domain
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies)
PQQ_2 (PF13360, IPR002372): PQQ-like domain
LRR_8 (PF13855, IPR001611): Leucine rich repeat
COR (PF16095, IPR032171): C-terminal of Roc, COR, domain
112 MALT1oncoprotein90.6075.086Peptidase_C14 (PF00656, IPR011600): Caspase domain
V-set (PF07686, IPR013106): Immunoglobulin V-set domain
Ig_2 (PF13895, IPR007110): Immunoglobulin domain
Ig_3 (PF13927): Immunoglobulin domain
113 MAP3K11interactor110.7112.509APG6 (PF04111, IPR007243): Autophagy protein Apg6
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
SH3_9 (PF14604, IPR001452): Variant SH3 domain
114 MAP3K2protein found in more fusions40.6670.200PB1 (PF00564, IPR000270, SM00666): PB1 domain
Pkinase (PF00069, IPR000719): Protein kinase domain
115 MAP3K5oncoprotein170.38327.895Pkinase (PF00069, IPR000719): Protein kinase domain
DUF4071 (PF13281, IPR025136): Domain of unknown function (DUF4071)
116 MAP3K7oncoprotein190.36638.977Mnd1 (PF03962, IPR005647): Mnd1 family
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
117 MAPTprotein found in more fusions240.37276.200Tubulin-binding (PF00418, IPR001084): Tau and MAP protein, tubulin-binding repeat
118 MCF2oncoprotein41.0000PH (PF00169, IPR001849, SM00233): PH domain
RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain
Spectrin (PF00435, IPR002017): Spectrin repeat
CRAL_TRIO_2 (PF13716, IPR001251): Divergent CRAL/TRIO domain
SPG48 (PF14764, IPR028222): AP-5 complex subunit, vesicle trafficking
119 MEN1suppressor110.6009.002Menin (PF05053, IPR007747): Menin
120 METoncoprotein60.8670.325Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
PSI (PF01437, IPR002165, SM00423): Plexin repeat
Sema (PF01403, IPR001627, SM00630): Sema domain
TIG (PF01833, IPR002909): IPT/TIG domain
121 MIFoncoprotein80.5714.995MIF (PF01187, IPR001398): Macrophage migration inhibitory factor (MIF)
122 MITFoncoprotein40.5001.333HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
DUF3371 (PF11851, IPR021802): Domain of unknown function (DUF3371)
DUF4355 (PF14265, IPR025580): Domain of unknown function (DUF4355)
Di19_C (PF14571, IPR027935): Stress-induced protein Di19, C-terminal
MITF_TFEB_C_3_N (PF15951, IPR031867): MITF/TFEB/TFEC/TFE3 N-terminus
123 MKKSinteractor51.0000Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
124 MLF2interactor120.5308.214Mlf1IP (PF10248, IPR019376): Myelodysplasia-myeloid leukemia factor 1-interacting protein
125 MOV10interactor270.199141.958AAA_12 (PF13087): AAA domain
AAA_30 (PF13604): AAA domain
126 MPP1oncoprotein100PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
SH3_2 (PF07653, IPR011511): Variant SH3 domain
Guanylate_kin (PF00625, IPR008145, SM00072): Guanylate kinase
P33MONOX (PF15302, IPR026759): P33 mono-oxygenase
127 MST1Rsuppressor41.0000Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
PSI (PF01437, IPR002165, SM00423): Plexin repeat
Sema (PF01403, IPR001627, SM00630): Sema domain
TIG (PF01833, IPR002909): IPT/TIG domain
128 MYConcoprotein320.243169.817HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
Myc-LZ (PF02344, IPR003327): Myc leucine zipper domain
Myc_N (PF01056, IPR012682): Myc amino-terminal region
129 MYOCDinteractor60.6001.318BES1_N (PF05687, IPR008540): BES1/BZR1 plant transcription factor, N-terminal
IncA (PF04156, IPR007285): IncA protein
RPEL (PF02755, IPR004018, SM00707): RPEL repeat
SAP (PF02037, IPR003034, SM00513): SAP domain
Totivirus_coat (PF05518, IPR008871): Totivirus coat protein
130 NADSYN1interactor100CN_hydrolase (PF00795, IPR003010): Carbon-nitrogen hydrolase
NAD_synthase (PF02540, IPR022310): NAD synthase
131 NHLRC1interactor90.3576.660NHL (PF01436, IPR001258): NHL repeat
zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger
zf-RING_5 (PF14634, IPR001841): zinc-RING finger domain
132 NLRP3oncoprotein31.0000NACHT (PF05729): NACHT domain
PYRIN (PF02758, IPR004020): PAAD/DAPIN/Pyrin domain
LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies)
LRR_6 (PF13516, IPR001611): Leucine Rich repeat
LRR_8 (PF13855, IPR001611): Leucine rich repeat
FISNA (PF14484, IPR029495): Fish-specific NACHT associated domain
133 NOS1interactor21.0000FAD_binding_1 (PF00667, IPR003097): FAD binding domain
Flavodoxin_1 (PF00258, IPR008254): Flavodoxin
NAD_binding_1 (PF00175, IPR001433): Oxidoreductase NAD-binding domain
NO_synthase (PF02898, IPR004030): Nitric oxide synthase, oxygenase domain
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
134 NOS2interactor200.41529.192FAD_binding_1 (PF00667, IPR003097): FAD binding domain
Flavodoxin_1 (PF00258, IPR008254): Flavodoxin
NAD_binding_1 (PF00175, IPR001433): Oxidoreductase NAD-binding domain
NO_synthase (PF02898, IPR004030): Nitric oxide synthase, oxygenase domain
135 NOX5interactor31.0000FAD_binding_8 (PF08022, IPR013112): FAD-binding domain
Ferric_reduct (PF01794, IPR013130): Ferric reductase like transmembrane component
NAD_binding_6 (PF08030, IPR013121): Ferric reductase NAD binding domain
EF-hand_6 (PF13405, IPR002048): EF-hand domain
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
EF-hand_8 (PF13833, IPR002048): EF-hand domain pair
136 NQO1oncoprotein70.7330.647Flavodoxin_2 (PF02525, IPR003680): Flavodoxin-like fold
137 NR3C1protein found in more fusions210.35349.805GCR (PF02155, IPR001409): Glucocorticoid receptor
zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains)
Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
138 NR3C2oncoprotein51.0000CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
BES1_N (PF05687, IPR008540): BES1/BZR1 plant transcription factor, N-terminal
zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains)
Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
139 NUBP2interactor90.36113.652ParA (PF10609, IPR019591): NUBPL iron-transfer P-loop NTPase
140 NUDCD2interactor130.28240.206CS (PF04969, IPR007052): CS domain
DUF3110 (PF11360, IPR021503): Protein of unknown function (DUF3110)
141 NXF1interactor390.189318.195NTF2 (PF02136, IPR002075): Nuclear transport factor 2 (NTF2) domain
Tap-RNA_bind (PF09162, IPR015245): Tap, RNA-binding
TAP_C (PF03943, IPR005637, SM00804): TAP C-terminal domain
LRR_8 (PF13855, IPR001611): Leucine rich repeat
142 OLA1interactor50.7001.050Roc (PF08477, IPR013684): Ras of Complex, Roc, domain of DAPkinase
MMR_HSR1 (PF01926, IPR006073): 50S ribosome-binding GTPase
YchF-GTPase_C (PF06071, IPR013029): Protein of unknown function (DUF933)
143 OLFM3interactor21.0000Dynactin_p22 (PF07426, IPR009991): Dynactin subunit p22
OLF (PF02191, IPR003112, SM00284): Olfactomedin-like domain
Noelin-1 (PF12308, IPR022082): Neurogenesis glycoprotein
Helo_like_N (PF17111, IPR031348): Fungal N-terminal domain of STAND proteins
144 OTUB1interactor270.256144.053Peptidase_C65 (PF10275, IPR019400): Peptidase C65 Otubain
145 PA2G4interactor90.4177.958Peptidase_M24 (PF00557, IPR001714): Metallopeptidase family M24
Ribosomal_S25 (PF03297, IPR004977): S25 ribosomal protein
TraC (PF07820, IPR012930): TraC-like protein
146 PACRGsuppressor100.6445.399ParcG (PF10274, IPR019399): Parkin co-regulated protein
147 PAICSinteractor60.4002.976AIRC (PF00731, IPR000031, SM01001): AIR carboxylase
SAICAR_synt (PF01259, IPR028923): SAICAR synthetase
148 PARK2suppressor480.243385.667IBR (PF01485, IPR002867, SM00647): IBR domain, a half RING-finger domain
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
149 PARK7suppressor190.30141.460DJ-1_PfpI (PF01965, IPR002818): DJ-1/PfpI family
150 PCSK9interactor60.4004.826Peptidase_S8 (PF00082, IPR000209): Subtilase family
Inhibitor_I9 (PF05922, IPR010259): Peptidase inhibitor I9
151 PELI3interactor70.6192.960Pellino (PF04710, IPR006800): Pellino
152 PFN1suppressor21.0000Profilin (PF00235, IPR005455, SM00392): Profilin
153 PGRsuppressor60.6000.872Prog_receptor (PF02161, IPR000128): Progesterone receptor
zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains)
Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
154 PHKG2interactor40.8330.154APH (PF01636, IPR002575): Phosphotransferase enzyme family
Pkinase (PF00069, IPR000719): Protein kinase domain
155 POLBinteractor100DNA_pol_lambd_f (PF10391, IPR018944): Fingers domain of DNA polymerase lambda
HHH_2 (PF12826): Helix-hairpin-helix motif
HHH_8 (PF14716, IPR010996): Helix-hairpin-helix domain
DNA_pol_B_thumb (PF14791, IPR029398): DNA polymerase beta thumb
DNA_pol_B_palm (PF14792, IPR028207): DNA polymerase beta palm
156 POT1interactor140.44923.955POT1 (PF02765, IPR011564, SM00976): Telomeric single stranded DNA binding POT1/CDC13
tRNA_anti-codon (PF01336, IPR004365): OB-fold nucleic acid binding domain
POT1PC (PF16686, IPR032042): ssDNA-binding domain of telomere protection protein
157 PPP2R1Aoncoprotein240.33372.220TAF6_C (PF07571, IPR011442): TAF6 C-terminal HEAT repeat domain
HEAT (PF02985, IPR000357): HEAT repeat
HEAT_PBS (PF03130, IPR004155, SM00567): PBS lyase HEAT-like repeat
HEAT_2 (PF13646): HEAT repeats
158 PRKCZinteractor180.38232.143PB1 (PF00564, IPR000270, SM00666): PB1 domain
Pkinase (PF00069, IPR000719): Protein kinase domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain)
159 PRMT5protein found in more fusions140.33330.884PRMT5 (PF05185, IPR025799): PRMT5 arginine-N-methyltransferase
160 PRPF19protein found in more fusions140.48711.788Prp19 (PF08606, IPR013915): Prp19/Pso4-like
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
U-box (PF04564, IPR003613, SM00504): U-box domain
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
161 PSMA3interactor280.368104.290Proteasome (PF00227, IPR001353): Proteasome subunit
Proteasome_A_N (PF10584, IPR000426, SM00948): Proteasome subunit A N-terminal signature
162 PSMD1interactor240.33788.028PA26 (PF04636, IPR006730): PA26 p53-induced protein (sestrin)
PC_rep (PF01851, IPR002015): Proteasome/cyclosome repeat
HEAT_2 (PF13646): HEAT repeats
163 PSMD14interactor110.56415.548JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease
MitMem_reg (PF13012, IPR024969): Maintenance of mitochondrial structure and function
164 PSMD4interactor220.35569.169UIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif
VWA_2 (PF13519, IPR002035): von Willebrand factor type A domain
165 PTENsuppressor190.38044.227DSPc (PF00782, IPR020422, SM00195): Dual specificity phosphatase, catalytic domain
PTEN_C2 (PF10409, IPR014020): C2 domain of PTEN tumour-suppressor protein
166 PTGES3interactor260.283102.490CS (PF04969, IPR007052): CS domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
167 PTK2protein found in more fusions90.7142.131FERM_M (PF00373, IPR019748): FERM central domain
Focal_AT (PF03623, IPR005189): Focal adhesion targeting region
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
UCMA (PF17085, IPR031386): Unique cartilage matrix associated protein
168 RAD23Bsuppressor150.43827.105K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain
UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
XPC-binding (PF09280, IPR015360): XPC-binding domain
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
DUF3123 (PF11321, IPR021470): Protein of unknown function (DUF3123)
169 RAF1oncoprotein280.33996.394Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
RBD (PF02196, IPR003116, SM00455): Raf-like Ras-binding domain
C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain)
170 RELAoncoprotein350.217232.719DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region
RHD_DNA_bind (PF00554, IPR011539): Rel homology DNA-binding domain
RHD_dimer (PF16179, IPR032397): Rel homology dimerisation domain
171 RPS6KB2interactor190.43929.029Pkinase (PF00069, IPR000719): Protein kinase domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
172 RUNX1suppressor120.38224.572Runt (PF00853, IPR013524): Runt domain
RunxI (PF08504, IPR013711): Runx inhibition domain
DUF3037 (PF11236, IPR021398): Protein of unknown function (DUF3037)
173 RUNX2suppressor100.5338.887DUF1180 (PF06679, IPR009565): Protein of unknown function (DUF1180)
Runt (PF00853, IPR013524): Runt domain
TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360)
DUF2722 (PF10846, IPR021216): Protein of unknown function (DUF2722)
174 RUSC1interactor31.0000RUN (PF02759, IPR004012, SM00593): RUN domain
MAGE_N (PF12440, IPR021072): Melanoma associated antigen family N terminal
SH3_9 (PF14604, IPR001452): Variant SH3 domain
175 S100A2suppressor200S_100 (PF01023, IPR013787): S-100/ICaBP type calcium binding domain
EF-hand_4 (PF12763, IPR000261): Cytoskeletal-regulatory complex EF hand
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
176 S100A6interactor50.6671.500S_100 (PF01023, IPR013787): S-100/ICaBP type calcium binding domain
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
177 S100Poncoprotein40.6670.250S_100 (PF01023, IPR013787): S-100/ICaBP type calcium binding domain
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
178 SEC23Ainteractor70.33310.167Gelsolin (PF00626, IPR007123): Gelsolin repeat
Sec23_BS (PF08033, IPR012990): Sec23/Sec24 beta-sandwich domain
Sec23_helical (PF04815, IPR006900): Sec23/Sec24 helical domain
Sec23_trunk (PF04811, IPR006896): Sec23/Sec24 trunk domain
zf-Sec23_Sec24 (PF04810, IPR006895): Sec23/Sec24 zinc finger
APP_E2 (PF12925, IPR024329): E2 domain of amyloid precursor protein
179 SEC24Ainteractor60.4006.567Gelsolin (PF00626, IPR007123): Gelsolin repeat
Sec23_BS (PF08033, IPR012990): Sec23/Sec24 beta-sandwich domain
Sec23_helical (PF04815, IPR006900): Sec23/Sec24 helical domain
Sec23_trunk (PF04811, IPR006896): Sec23/Sec24 trunk domain
zf-Sec23_Sec24 (PF04810, IPR006895): Sec23/Sec24 zinc finger
180 SENP3interactor100.5337.165Nop53 (PF07767, IPR011687): Nop53 (60S ribosomal biogenesis)
Peptidase_C48 (PF02902, IPR003653): Ulp1 protease family, C-terminal catalytic domain
181 SGK1oncoprotein100.5833.704Pkinase (PF00069, IPR000719): Protein kinase domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
PX (PF00787, IPR001683, SM00312): PX domain
182 SH3BGRLinteractor31.0000SH3BGR (PF04908, IPR006993): SH3-binding, glutamic acid-rich protein
183 SHFM1interactor120.5459.210CLLAC (PF15675, IPR031379): CLLAC-motif containing domain
184 SIRT6suppressor100.35611.167SIR2 (PF02146, IPR003000): Sir2 family
TPP_enzyme_M (PF00205, IPR012000): Thiamine pyrophosphate enzyme, central domain
185 SKP2suppressor130.38527.362LRR_1 (PF00560, IPR001611): Leucine Rich Repeat
LRR_2 (PF07723, IPR013101): Leucine Rich Repeat
LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies)
F-box-like (PF12937, IPR001810): F-box-like
LRR_6 (PF13516, IPR001611): Leucine Rich repeat
LRR_8 (PF13855, IPR001611): Leucine rich repeat
186 SLC12A3interactor50.9000.091AA_permease (PF00324, IPR004841): Amino acid permease
AA_permease_N (PF08403, IPR013612): Amino acid permease N-terminal
SLC12 (PF03522, IPR018491): Solute carrier family 12
187 SMAD1interactor150.45121.590MH1 (PF03165, IPR003619, SM00523): MH1 domain
MH2 (PF03166, IPR001132, SM00524): MH2 domain
188 SMAD2suppressor200.39251.649MH1 (PF03165, IPR003619, SM00523): MH1 domain
MH2 (PF03166, IPR001132, SM00524): MH2 domain
189 SMAD3oncoprotein310.292149.127MH1 (PF03165, IPR003619, SM00523): MH1 domain
MH2 (PF03166, IPR001132, SM00524): MH2 domain
190 SMAD4suppressor130.50014.413MH1 (PF03165, IPR003619, SM00523): MH1 domain
MH2 (PF03166, IPR001132, SM00524): MH2 domain
191 SMAD5interactor90.7223.702MH1 (PF03165, IPR003619, SM00523): MH1 domain
MH2 (PF03166, IPR001132, SM00524): MH2 domain
192 SMG5interactor60.4672.084EST1 (PF10374, IPR019458): Telomerase activating protein Est1
EST1_DNA_bind (PF10373, IPR018834): Est1 DNA/RNA binding domain
PIN_4 (PF13638, IPR002716): PIN domain
193 SNAI2oncoprotein60.4671.292zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
KCNQ2_u3 (PF16642): Unstructured region on Potassium channel subunit alpha KvLQT2
194 SNCAinteractor240.44748.265Synuclein (PF01387, IPR001058): Synuclein
195 SOD1interactor150.31932.774Sod_Cu (PF00080, IPR001424): Copper/zinc superoxide dismutase (SODC)
196 SP7interactor100zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
197 SQSTM1oncoprotein290.291127.169PB1 (PF00564, IPR000270, SM00666): PB1 domain
ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type
UBA_5 (PF16577, IPR015940): UBA domain
198 SRConcoprotein310.274160.128Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
SH2 (PF00017, IPR000980, SM00252): SH2 domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
199 SRXN1interactor41.0000ParBc (PF02195, IPR003115): ParB-like nuclease domain
200 STAMinteractor70.4767.687GAT (PF03127, IPR004152): GAT domain
UIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif
VHS (PF00790, IPR002014, SM00288): VHS domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
201 STILoncoprotein60.6002.121STIL_N (PF15253, IPR026123): SCL-interrupting locus protein N-terminus
202 STK11suppressor80.5006.781Pkinase (PF00069, IPR000719): Protein kinase domain
203 SULT1A1interactor90.5289.117Sulfotransfer_1 (PF00685, IPR000863): Sulfotransferase domain
204 TAL1oncoprotein40.6670.667HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
SelK_SelG (PF10961, IPR024491): Selenoprotein SelK_SelG
205 TEAD3interactor40.6671.000TEA (PF01285, IPR000818, SM00426): TEA/ATTS domain family
206 TERF1interactor180.41243.735TRF (PF08558, IPR013867): Telomere repeat binding factor (TRF)
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
207 TERF2interactor130.51514.450Aconitase_C (PF00694, IPR000573): Aconitase C-terminal domain
TRF (PF08558, IPR013867): Telomere repeat binding factor (TRF)
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
TERF2_RBM (PF16772, IPR031902): Telomeric repeat-binding factor 2 Rap1-binding motif
208 TERToncoprotein150.32435.884RVT_1 (PF00078, IPR000477): Reverse transcriptase (RNA-dependent DNA polymerase)
Telomerase_RBD (PF12009, IPR021891, SM00975): Telomerase ribonucleoprotein complex - RNA binding domain
209 TINF2interactor90.8571.057TINF2_N (PF14973, IPR029400): TERF1-interacting nuclear factor 2 N-terminus
210 TLR4interactor80.6071.971LRR_1 (PF00560, IPR001611): Leucine Rich Repeat
TIR (PF01582, IPR000157, SM00255): TIR domain
LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies)
LRR_8 (PF13855, IPR001611): Leucine rich repeat
LRR_9 (PF14580): Leucine-rich repeat
211 TLR9interactor60.7330.605LRR_1 (PF00560, IPR001611): Leucine Rich Repeat
TIR (PF01582, IPR000157, SM00255): TIR domain
LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies)
LRR_6 (PF13516, IPR001611): Leucine Rich repeat
LRR_8 (PF13855, IPR001611): Leucine rich repeat
212 TOMM40interactor51.0000Porin_3 (PF01459, IPR027246): Eukaryotic porin
213 TP53suppressor700.1691119.549DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region
P53 (PF00870, IPR011615): P53 DNA-binding domain
P53_tetramer (PF07710, IPR010991): P53 tetramerisation motif
214 TPM1protein found in more fusions140.30833.743Tropomyosin (PF00261, IPR000533): Tropomyosin
Tropomyosin_1 (PF12718, IPR000533): Tropomyosin like
215 TRAF2interactor240.273100.130MATH (PF00917, IPR002083, SM00061): MATH domain
Sina (PF03145, IPR018121): Seven in absentia protein family
SlyX (PF04102, IPR007236): SlyX
zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger)
zf-TRAF (PF02176, IPR001293): TRAF-type zinc finger
TRAF_BIRC3_bd (PF16673, IPR032070): TNF receptor-associated factor BIRC3 binding domain
zf-C3HC4_5 (PF17121, IPR001841): Zinc finger, C3HC4 type (RING finger)
216 TRAF6protein found in more fusions450.201433.256SlyX (PF04102, IPR007236): SlyX
zf-TRAF (PF02176, IPR001293): TRAF-type zinc finger
zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
217 TXLNGinteractor40.5000.733FlaC_arch (PF05377, IPR008039): Flagella accessory protein C (FlaC)
Taxilin (PF09728, IPR026183): Myosin-like coiled-coil protein
218 TXN2interactor80.3216.203Thioredoxin (PF00085, IPR013766): Thioredoxin
219 UBCprotein found in more fusions670.174997.283ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
220 UBE2D1interactor210.25377.602UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
221 UBE2D2oncoprotein180.39035.100UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
222 UBE2D3interactor150.29725.384UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
223 UBE2E1protein found in more fusions110.24410.638UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein
224 UBE2E2protein found in more fusions60.5001.098UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
225 UBE2E3interactor50.6670.667UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
226 UBE2L3interactor210.31654.728UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
227 UBE2Nprotein found in more fusions200.36852.452UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
228 UBE2Q1interactor21.0000Josephin (PF02099, IPR006155): Josephin
RWD (PF05773, IPR006575, SM00591): RWD domain
UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
KIAA1430 (PF13879, IPR029488): KIAA1430 homologue
229 UBE2V1interactor130.51318.118UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
230 UBE2V2interactor120.48517.359UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
231 UBE2Winteractor50.5000.690UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
232 UBE4Bsuppressor140.34623.614DUF1180 (PF06679, IPR009565): Protein of unknown function (DUF1180)
NUDE_C (PF04880, IPR006964): NUDE protein, C-terminal conserved region
Ufd2P_core (PF10408, IPR019474): Ubiquitin elongating factor core
U-box (PF04564, IPR003613, SM00504): U-box domain
DUF4568 (PF15132, IPR027919): Domain of unknown function (DUF4568)
233 UBXN10interactor30.6670.143UBX (PF00789, IPR001012, SM00166): UBX domain
234 USP19interactor110.41812.249CS (PF04969, IPR007052): CS domain
UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase
USP19_linker (PF16602): Linker region of USP19 deubiquitinase
235 USP5interactor90.4725.932UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase
zf-UBP (PF02148, IPR001607, SM00290): Zn-finger in ubiquitin-hydrolases and other protein
236 VCPprotein found in more fusions480.238449.609AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA)
CDC48_2 (PF02933, IPR004201, SM01072): Cell division protein 48 (CDC48), domain 2
CDC48_N (PF02359, IPR003338, SM01073): Cell division protein 48 (CDC48), N-terminal domain
TniB (PF05621, IPR008868): Bacterial TniB protein
Vps4_C (PF09336, IPR015415): Vps4 C terminal oligomerisation domain
DUF3944 (PF13099, IPR025217): Domain of unknown function (DUF3944)
237 VHLsuppressor240.33269.970Trypan_PARP (PF05887, IPR008882): Procyclic acidic repetitive protein (PARP)
VHL (PF01847, IPR022772): von Hippel-Lindau disease tumour suppressor protein
VHL_C (PF17211): VHL box domain
238 XIAPinteractor240.265107.695BIR (PF00653, IPR001370, SM00238): Inhibitor of Apoptosis domain
zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
239 YAP1suppressor190.25187.425Bindin (PF02084, IPR000775): Bindin
WW (PF00397, IPR001202, SM00456): WW domain
GspL_C (PF12693, IPR025691): GspL periplasmic domain
FAM181 (PF15238, IPR029359): FAM181

B a c k    t o    T o p ⇑