Find Fusion Network

Visualization interactions

Powered by Cytoscape Web for: parental proteins STAT1 (from a repository: Thu Nov 24 08:24:18 2016)

Examples AFF1 MLL ACTN4 + MLLAFF1 + MLLALK + MSNALK + TFGALK + TPM3ALK + TPM4ASXL2 + KAT6AATF1 + FUSBCR + ABL1BCR + FGFR1CCND1 + TACSTD2CD74 + ROS1CDK6 + MLLCOL1A1 + PDGFBCREB3L2 + PPARGCREB3L2 + FUSCREBBP + KAT6ADAZAP1 + MEF2DELL + MLLEPS15 + MLLERG + EWSR1ERG + FUSERG + TMPRSS2ETV5 + TMPRSS2ETV6 + ABL1ETV6 + NTRK3ETV6 + PAX5EWSR1 + FLI1EWSR1 + WT1FOXO1 + PAX3FOXP1 + PAX5FRYL + MLLGAS7 + MLLGMPS + MLLGOLGA5 + RETHOOK3 + RETHOXC13 + NUP98HOXD13 + NUP98MECOM + RUNX1MKL1 + RBM15MLL + MLLT1MLL + MLLT4MLL + MLLT10MLL + PICALMMLLT10 + PICALMNCOA1 + PAX3NIN + PDGFRBNPM1 + RARANRG1 + ODZ4NTRK1 + TFGNUMA1 + RARANUP98 + PHF23PAX5 + ZNF521PBX1 + TCF3RET + TRIM27ROS1 + SLC34A2PML + RARAPRKAR1A + RARAPRKAR1A + RETRUNX1 + RUNX1T1RUNX1 + SH3D19	Cytoscape Web will replace the contents your graph	PPI Properties: Click on nodes or edges
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Statistics and Network structure information

Statistic of PPI Value(s) The number of interactors (fusion and proteins) 147 The number (and %) of the onco-proteins 50 (34.01 %) The number (and %) of the tumor suppressors 25 (17.01 %) Total number of binary PPIs (saturation %) 870 (8.11 %) The number (and %) of affected PPIs 147 (16.90 %) The number of possible different fusions 41 PPI diameter 2 PPI radius 1 The average degree of PPI 10.830 Assortativity coefficient -0.2263 The network average Clustering coefficient 0.521 The number (and %) of a zero Clustering coefficients 6 (4.08 %) The number (and %) of a zero Betweenness Centrality 22 (14.97 %)

ACTIVE INTERACTORS

List of the fusions
PPI for parental proteins: STAT1	All fusions
Proteins found in more fusions	PPARD (see 1 fusions); HLA-B (see 2 fusions); RNF11 (see 1 fusions); VDR (see 2 fusions); VCP (see 4 fusions); LZTR1 (see 2 fusions); TRIM28 (see 1 fusions); GFAP (see 3 fusions); U2AF2 (see 2 fusions); JAK2 (see 3 fusions); HSF1 (see 3 fusions); PRKCD (see 2 fusions); APEH (see 1 fusions); HUWE1 (see 2 fusions); HSP90AB1 (see 1 fusions); HDAC4 (see 1 fusions); ATP6V1C1 (see 3 fusions); VPS26A (see 1 fusions); TNFRSF1A (see 2 fusions); CREBBP (see 6 fusions); STAT3 (see 2 fusions); EIF2AK2 (see 1 fusions); PIAS1 (see 2 fusions); EGFR (see 2 fusions); RACK1 (see 3 fusions); SNX1 (see 1 fusions); CTTN (see 1 fusions); FOS (see 4 fusions); JAK1 (see 1 fusions); RXRA (see 2 fusions); PTK2 (see 2 fusions); EP300 (see 1 fusions); PAK2 (see 2 fusions); MTOR (see 1 fusions); DDB1 (see 2 fusions); PML (see 4 fusions); PRKCE (see 3 fusions); DTX3L (see 2 fusions); STAT1 (see 1 fusions); CTNNBL1 (see 1 fusions);

List of active interactors

#	Name	Type	Number of PPI (degree)	Clustering Coefficient	Betweenness Centrality	Domains (Pfam, InterPro, SMART): description
1	STAT1	parental protein	147	0.061	15036.622	SH2 (PF00017, IPR000980, SM00252): SH2 domain STAT_alpha (PF01017, IPR013800): STAT protein, all-alpha domain STAT_bind (PF02864, IPR013801): STAT protein, DNA binding domain STAT_int (PF02865, IPR013799, SM00964): STAT protein, protein interaction domain STAT1_TAZ2bind (PF12162, IPR022752): STAT1 TAZ2 binding domain
2	AARS	interactor	7	0.476	7.422	DHHA1 (PF02272, IPR003156): DHHA1 domain Syntaxin-6_N (PF09177, IPR015260): Syntaxin 6, N-terminal tRNA-synt_2c (PF01411, IPR018164): tRNA synthetases class II (A) tRNA_SAD (PF07973, IPR012947, SM00863): Threonyl and Alanyl tRNA synthetase second additional domain
3	ACTN4	interactor	9	0.472	10.021	CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain EFhand_Ca_insen (PF08726, IPR014837): Ca2+ insensitive EF hand Spectrin (PF00435, IPR002017): Spectrin repeat EF-hand_7 (PF13499, IPR011992): EF-hand domain pair Uds1 (PF15456, IPR029191): Up-regulated During Septation
4	AHSA1	interactor	7	0.667	3.550	Aha1_N (PF09229, IPR015310, SM01000): Activator of Hsp90 ATPase, N-terminal AHSA1 (PF08327, IPR013538): Activator of Hsp90 ATPase homolog 1-like protein
5	APEH	oncoprotein	15	0.429	30.663	Peptidase_S9 (PF00326, IPR001375): Prolyl oligopeptidase family
6	ARRB2	interactor	14	0.286	37.914	Arrestin_C (PF02752, IPR011022, SM01017): Arrestin (or S-antigen), C-terminal domain Arrestin_N (PF00339, IPR011021): Arrestin (or S-antigen), N-terminal domain
7	ATF3	suppressor	12	0.673	5.363	bZIP_1 (PF00170, IPR004827): bZIP transcription factor
8	ATG7	interactor	12	0.606	11.421	ThiF (PF00899, IPR000594): ThiF family ATG7_N (PF16420, IPR032197): Ubiquitin-like modifier-activating enzyme ATG7 N-terminus
9	ATP6V1C1	protein found in more fusions	14	0.654	11.001	V-ATPase_C (PF03223, IPR004907): V-ATPase subunit C
10	BCL3	oncoprotein	8	0.714	1.772	Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_4 (PF13637): Ankyrin repeats (many copies)
11	BPIFB3	interactor	1	0	0	LBP_BPI_CETP (PF01273, IPR017942, SM00328): LBP / BPI / CETP family, N-terminal domain LBP_BPI_CETP_C (PF02886, IPR001124, SM00329): LBP / BPI / CETP family, C-terminal domain
12	BRCA1	suppressor	26	0.267	133.977	BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger) BRCT_assoc (PF12820, IPR025994): Serine-rich domain associated with BRCT
13	CAND1	interactor	20	0.322	71.391	Adaptin_N (PF01602, IPR002553): Adaptin N terminal region DUF1981 (PF09324, IPR015403): Domain of unknown function (DUF1981) HEAT (PF02985, IPR000357): HEAT repeat TIP120 (PF08623, IPR013932): TATA-binding protein interacting (TIP20) RTP1_C1 (PF10363, IPR019451): Required for nuclear transport of RNA pol II C-terminus 1 DUF3385 (PF11865, IPR024585): Domain of unknown function (DUF3385) MMS19_C (PF12460, IPR024687): RNAPII transcription regulator C-terminal Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region HEAT_EZ (PF13513): HEAT-like repeat HEAT_2 (PF13646): HEAT repeats MMS19_N (PF14500): Dos2-interacting transcription regulator of RNA-Pol-II
14	CASP3	interactor	6	0.500	3.667	Peptidase_C14 (PF00656, IPR011600): Caspase domain
15	CASP7	interactor	6	0.600	3.333	Peptidase_C14 (PF00656, IPR011600): Caspase domain PRIMA1 (PF16101): Proline-rich membrane anchor 1
16	CCDC8	interactor	16	0.305	41.096	Borrelia_P83 (PF05262, IPR007926): Borrelia P83/100 protein SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal PNMA (PF14893, IPR026523): PNMA
17	CIAPIN1	interactor	5	0.667	1.667	CIAPIN1 (PF05093, IPR007785): Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis Methyltransf_11 (PF08241, IPR013216): Methyltransferase domain Methyltransf_31 (PF13847, IPR025714): Methyltransferase domain
18	CREBBP	suppressor	25	0.409	83.838	Creb_binding (PF09030, IPR014744): Creb binding DUF902 (PF06001, IPR010303): Domain of Unknown Function (DUF902) Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region KIX (PF02172, IPR003101): KIX domain MAS20 (PF02064, IPR002056): MAS20 protein import receptor TPX2 (PF06886, IPR027329): Targeting protein for Xklp2 (TPX2) zf-TAZ (PF02135, IPR000197, SM00551): TAZ zinc finger ANAPC_CDC26 (PF10471, IPR018860): Anaphase-promoting complex APC subunit CDC26 HAT_KAT11 (PF08214, IPR013178): Histone acetylation protein Bromodomain (PF00439, IPR001487, SM00297): Bromodomain ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type DUF3729 (PF12526, IPR022202): Protein of unknown function (DUF3729) DUF4834 (PF16118, IPR032272): Domain of unknown function (DUF4834)
19	CTNNBL1	protein found in more fusions	4	0.667	0.667	Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat DASH_Dad4 (PF08650, IPR013959): DASH complex subunit Dad4 CTNNBL (PF08216, IPR013180, SM01156): Catenin-beta-like, Arm-motif containing nuclear Atx10homo_assoc (PF09759, IPR019156): Spinocerebellar ataxia type 10 protein domain
20	CTTN	oncoprotein	18	0.412	49.463	FadA (PF09403, IPR018543): Adhesion protein FadA HS1_rep (PF02218, IPR003134): Repeat in HS1/Cortactin SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
21	DCTN1	interactor	7	0.667	3.389	Bap31 (PF05529, IPR008417): B-cell receptor-associated protein 31-like CAP_GLY (PF01302, IPR000938, SM01052): CAP-Gly domain FlgN (PF05130, IPR007809): FlgN protein HOOK (PF05622, IPR008636): HOOK protein SlyX (PF04102, IPR007236): SlyX TSC22 (PF01166, IPR000580): TSC-22/dip/bun family DUF2443 (PF10398, IPR019469): Protein of unknown function (DUF2443) ADIP (PF11559, IPR021622): Afadin- and alpha -actinin-Binding TMF_DNA_bd (PF12329, IPR022092): TATA element modulatory factor 1 DNA binding Dynactin (PF12455, IPR022157): Dynein associated protein Lebercilin (PF15619, IPR028933): Ciliary protein causing Leber congenital amaurosis disease KELK (PF15796, IPR031597): KELK-motif containing domain of MRCK Ser/Thr protein kinase
22	DDB1	protein found in more fusions	14	0.346	26.948	CPSF_A (PF03178, IPR004871): CPSF A subunit region MMS1_N (PF10433): Mono-functional DNA-alkylating methyl methanesulfonate N-term
23	DOT1L	oncoprotein	2	1.000	0	AT_hook (PF02178, IPR017956, SM00384): AT hook motif DivIC (PF04977, IPR007060): Septum formation initiator DOT1 (PF08123, IPR013110): Histone methylation protein DOT1 ZapB (PF06005, IPR009252): Cell division protein ZapB HALZ (PF02183, IPR003106, SM00340): Homeobox associated leucine zipper TraV (PF09676, IPR014118): Type IV conjugative transfer system lipoprotein (TraV)
24	DTX3L	protein found in more fusions	8	0.429	9.648	KH_1 (PF00013, IPR004088, SM00322): KH domain zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
25	E2F1	suppressor	7	0.810	1.155	Cellsynth_D (PF03500, IPR022798): Cellulose synthase subunit D E2F_TDP (PF02319, IPR003316): E2F/DP family winged-helix DNA-binding domain E2F_CC-MB (PF16421, IPR032198): E2F transcription factor CC-MB domain
26	EGFR	oncoprotein	35	0.207	302.542	Furin-like (PF00757, IPR006211): Furin-like cysteine rich region Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase Recep_L_domain (PF01030, IPR000494): Receptor L domain GAPT (PF11770, IPR021082): GRB2-binding adapter (GAPT) GF_recep_IV (PF14843, IPR032778): Growth factor receptor domain IV
27	EIF1AD	interactor	1	0	0	eIF-1a (PF01176, IPR006196): Translation initiation factor 1A / IF-1
28	EIF2AK2	oncoprotein	11	0.400	18.875	dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif Pkinase (PF00069, IPR000719): Protein kinase domain
29	ELP2	interactor	7	0.667	2.884	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Lar_restr_allev (PF14354): Restriction alleviation protein Lar
30	EP300	oncoprotein	32	0.237	241.645	Creb_binding (PF09030, IPR014744): Creb binding DUF902 (PF06001, IPR010303): Domain of Unknown Function (DUF902) Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region KIX (PF02172, IPR003101): KIX domain RR_TM4-6 (PF06459, IPR009460): Ryanodine Receptor TM 4-6 TPX2 (PF06886, IPR027329): Targeting protein for Xklp2 (TPX2) zf-TAZ (PF02135, IPR000197, SM00551): TAZ zinc finger HAT_KAT11 (PF08214, IPR013178): Histone acetylation protein Bromodomain (PF00439, IPR001487, SM00297): Bromodomain ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type
31	ERBB2	oncoprotein	9	0.714	2.712	Furin-like (PF00757, IPR006211): Furin-like cysteine rich region Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase Recep_L_domain (PF01030, IPR000494): Receptor L domain GF_recep_IV (PF14843, IPR032778): Growth factor receptor domain IV
32	FANCC	oncoprotein	5	0.400	5.000	Fanconi_C (PF02106, IPR000686): Fanconi anaemia group C protein
33	FANCE	oncoprotein	3	1.000	0	FA_FANCE (PF11510, IPR021025): Fanconi Anaemia group E protein FANCE DLEU7 (PF15760, IPR031510): Leukemia-associated protein 7
34	FOS	oncoprotein	12	0.600	7.219	bZIP_1 (PF00170, IPR004827): bZIP transcription factor
35	FOXA3	interactor	3	0.667	1.000	CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region HNF_C (PF09354, IPR018533): HNF3 C-terminal domain Forkhead (PF00250, IPR001766, SM00339): Forkhead domain
36	GFAP	protein found in more fusions	3	1.000	0	Filament (PF00038, IPR001664): Intermediate filament protein Filament_head (PF04732, IPR006821): Intermediate filament head (DNA binding) region
37	GNB2	interactor	8	0.536	5.275	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat CALM_bind (PF16025): Calcium-dependent calmodulin binding WD40_like (PF17005, IPR031544): WD40-like domain
38	GSPT2	interactor	9	0.833	1.688	GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2 GTP_EFTU_D3 (PF03143, IPR004160): Elongation factor Tu C-terminal domain PAM2 (PF07145, IPR009818): Ataxin-2 C-terminal region
39	GTF2I	interactor	8	0.536	3.361	GTF2I (PF02946, IPR004212): GTF2I-like repeat
40	HADH	interactor	2	1.000	0	3HCDH (PF00725, IPR006108): 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 3HCDH_N (PF02737, IPR006176): 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Collagen (PF01391, IPR008160): Collagen triple helix repeat (20 copies) Pyr_redox_2 (PF07992, IPR023753): Pyridine nucleotide-disulphide oxidoreductase
41	HDAC1	suppressor	25	0.355	91.993	FSAP_sig_propep (PF03032, IPR004275): Frog skin active peptide family signal and propeptide Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
42	HDAC3	suppressor	22	0.376	60.573	Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
43	HDAC4	oncoprotein	11	0.444	17.747	Borrelia_P83 (PF05262, IPR007926): Borrelia P83/100 protein Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit HDAC4_Gln (PF12203, IPR024643): Glutamine rich N terminal domain of histone deacetylase 4
44	HIRIP3	interactor	5	0.500	2.733	CHZ (PF09649, IPR019098, SM01082): Histone chaperone domain CHZ
45	HIST1H2BJ	interactor	5	0.500	4.667	Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
46	HIST2H3C	interactor	7	0.476	8.454	Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
47	HLA-B	oncoprotein	4	0.667	0.250	MHC_I (PF00129, IPR001039): Class I Histocompatibility antigen, domains alpha 1 and 2 MHC_I_C (PF06623, IPR010579): MHC_I C-terminus C1-set (PF07654, IPR003597, SM00407): Immunoglobulin C1-set domain
48	HLA-DRB5	interactor	2	1.000	0	MHC_II_beta (PF00969, IPR000353, SM00921): Class II histocompatibility antigen, beta domain C1-set (PF07654, IPR003597, SM00407): Immunoglobulin C1-set domain
49	HSF1	protein found in more fusions	9	0.464	12.033	DUF247 (PF03140, IPR004158): Plant protein of unknown function Vert_HS_TF (PF06546, IPR010542): Vertebrate heat shock transcription factor HSF_DNA-bind (PF00447, IPR000232, SM00415): HSF-type DNA-binding
50	HSP90AB1	oncoprotein	20	0.316	79.272	HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HSP90 (PF00183, IPR001404): Hsp90 protein
51	HSPA4L	interactor	6	0.533	5.686	HSP70 (PF00012, IPR013126): Hsp70 protein
52	HUWE1	oncoprotein	19	0.392	42.021	BUD22 (PF09073, IPR015158): BUD22 DUF908 (PF06012, IPR010309): Domain of Unknown Function (DUF908) DUF913 (PF06025, IPR010314): Domain of Unknown Function (DUF913) FdhE (PF04216, IPR006452): Protein involved in formate dehydrogenase formation HABP4_PAI-RBP1 (PF04774, IPR006861): Hyaluronan / mRNA binding family Ku_C (PF03730, IPR005160): Ku70/Ku80 C-terminal arm Merozoite_SPAM (PF07133, IPR010784): Merozoite surface protein (SPAM) Mucin (PF01456, IPR000458): Mucin-like glycoprotein Nop14 (PF04147, IPR007276): Nop14-like family PBP_sp32 (PF07222, IPR009865): Proacrosin binding protein sp32 RNA_pol_Rpc4 (PF05132, IPR007811): RNA polymerase III RPC4 TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain WWE (PF02825, IPR004170, SM00678): WWE domain HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase) Tim54 (PF11711, IPR021056): Inner membrane protein import complex subunit Tim54 U1snRNP70_N (PF12220, IPR022023): U1 small nuclear ribonucleoprotein of 70kDa MW N terminal DUF4414 (PF14377, IPR025527): Domain of unknown function (DUF4414)
53	IDE	interactor	10	0.600	10.174	Peptidase_M16 (PF00675, IPR011765): Insulinase (Peptidase family M16) Peptidase_M16_C (PF05193, IPR007863): Peptidase M16 inactive domain Peptidase_M16_M (PF16187, IPR032632): Middle or third domain of peptidase_M16
54	IFNAR2	interactor	7	0.600	4.300	Interfer-bind (PF09294, IPR015373): Interferon-alpha/beta receptor, fibronectin type III Tissue_fac (PF01108, IPR003961): Tissue factor
55	IFNGR1	interactor	6	0.533	4.348	IFNGR1 (PF07140, IPR021126): Interferon gamma receptor (IFNGR1) Interfer-bind (PF09294, IPR015373): Interferon-alpha/beta receptor, fibronectin type III Tissue_fac (PF01108, IPR003961): Tissue factor
56	IGBP1	interactor	2	1.000	0	TAP42 (PF04177, IPR007304): TAP42-like family
57	IL27RA	interactor	2	1.000	0	fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
58	IL2RB	oncoprotein	6	0.667	1.715	IL6Ra-bind (PF09240, IPR015321): Interleukin-6 receptor alpha chain, binding Pur_ac_phosph_N (PF16656, IPR015914): Purple acid Phosphatase, N-terminal domain
59	IRAK1	interactor	6	0.600	2.056	Death (PF00531, IPR000488, SM00005): Death domain Pkinase (PF00069, IPR000719): Protein kinase domain
60	IRF1	suppressor	6	0.667	1.971	IRF (PF00605, IPR001346, SM00348): Interferon regulatory factor transcription factor
61	IRF9	interactor	6	0.667	2.567	IRF (PF00605, IPR001346, SM00348): Interferon regulatory factor transcription factor IRF-3 (PF10401, IPR019471): Interferon-regulatory factor 3
62	ISG15	suppressor	9	0.417	9.327	ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
63	JAK1	oncoprotein	20	0.257	88.046	FERM_M (PF00373, IPR019748): FERM central domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain
64	JAK2	oncoprotein	18	0.294	64.119	FERM_M (PF00373, IPR019748): FERM central domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain
65	JMJD6	interactor	10	0.444	18.271	AF-4 (PF05110, IPR007797): AF-4 proto-oncoprotein JmjC (PF02373, IPR003347, SM00558): JmjC domain, hydroxylase SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein
66	JUN	oncoprotein	18	0.574	23.553	bZIP_1 (PF00170, IPR004827): bZIP transcription factor Jun (PF03957, IPR005643): Jun-like transcription factor
67	KARS	interactor	6	0.667	4.000	tRNA-synt_2 (PF00152, IPR004364): tRNA synthetases class II (D, K and N) tRNA_anti-codon (PF01336, IPR004365): OB-fold nucleic acid binding domain
68	KIT	oncoprotein	4	0.667	0.900	ig (PF00047, IPR013151, SM00409): Immunoglobulin domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase Ig_2 (PF13895, IPR007110): Immunoglobulin domain Ig_3 (PF13927): Immunoglobulin domain
69	KPNA1	interactor	6	0.600	4.267	Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat IBB (PF01749, IPR002652): Importin beta binding domain Arm_3 (PF16186, IPR032413): Atypical Arm repeat
70	LMO2	oncoprotein	6	0.500	3.315	CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal LIM (PF00412, IPR001781, SM00132): LIM domain
71	LZTR1	oncoprotein	3	1.000	0	BACK (PF07707, IPR011705, SM00875): BTB And C-terminal Kelch BTB (PF00651, IPR013069, SM00225): BTB/POZ domain Sigma70_r3 (PF04539, IPR007624): Sigma-70 region 3 Kelch_1 (PF01344, IPR006652, SM00612): Kelch motif Kelch_3 (PF13415): Galactose oxidase, central domain Kelch_4 (PF13418): Galactose oxidase, central domain Kelch_5 (PF13854): Kelch motif
72	MAVS	interactor	7	0.400	6.567	Ice_nucleation (PF00818, IPR000258): Ice nucleation protein repeat CARD_2 (PF16739, IPR031964): Caspase recruitment domain
73	MBD1	interactor	4	0.500	1.900	MBD (PF01429, IPR001739, SM00391): Methyl-CpG binding domain zf-CXXC (PF02008, IPR002857): CXXC zinc finger domain
74	MCM5	oncoprotein	8	0.429	12.243	MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family MCM_N (PF14551, IPR027925): MCM N-terminal domain MCM_OB (PF17207): MCM OB domain
75	MLST8	interactor	4	0.667	0.786	Hira (PF07569, IPR011494): TUP1-like enhancer of split WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160
76	MT-ND4L	interactor	1	0	0	NA
77	MTOR	oncoprotein	15	0.330	34.314	DUF1104 (PF06518, IPR009488): Protein of unknown function (DUF1104) EPSP_synthase (PF00275, IPR001986): EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) FAT (PF02259, IPR003151): FAT domain FATC (PF02260, IPR003152): FATC domain HEAT (PF02985, IPR000357): HEAT repeat FRB_dom (PF08771, IPR009076): FKBP12-rapamycin binding domain V-ATPase_H_N (PF03224, IPR004908): V-ATPase subunit H PI3_PI4_kinase (PF00454, IPR000403, SM00146): Phosphatidylinositol 3- and 4-kinase DUF3385 (PF11865, IPR024585): Domain of unknown function (DUF3385) HEAT_EZ (PF13513): HEAT-like repeat HEAT_2 (PF13646): HEAT repeats TPR_19 (PF14559): Tetratricopeptide repeat
78	NAA10	oncoprotein	9	0.472	12.467	Acetyltransf_1 (PF00583, IPR000182): Acetyltransferase (GNAT) family
79	NAA15	interactor	7	0.571	7.167	NARP1 (PF12569, IPR021183): NMDA receptor-regulated protein 1 ANAPC3 (PF12895): Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 (PF13176, IPR019734): Tetratricopeptide repeat TPR_8 (PF13181, IPR019734): Tetratricopeptide repeat TPR_9 (PF13371, IPR011990): Tetratricopeptide repeat TPR_11 (PF13414, IPR011990): TPR repeat TPR_12 (PF13424): Tetratricopeptide repeat TPR_19 (PF14559): Tetratricopeptide repeat
80	NFKBIA	oncoprotein	12	0.394	21.421	Ank (PF00023, IPR002110, SM00248): Ankyrin repeat Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_4 (PF13637): Ankyrin repeats (many copies) Ank_5 (PF13857): Ankyrin repeats (many copies)
81	NMD3	interactor	7	0.381	9.315	DUF1816 (PF08846, IPR014945): Domain of unknown function (DUF1816) NMD3 (PF04981, IPR007064): NMD3 family HGTP_anticodon2 (PF12745, IPR024435): Anticodon binding domain of tRNAs
82	NMI	interactor	10	0.389	14.448	IFP_35_N (PF07334, IPR009938): Interferon-induced 35 kDa protein (IFP 35) N-terminus NID (PF07292, IPR009909): Nmi/IFP 35 domain (NID)
83	NOMO1	interactor	2	1.000	0	DUF2012 (PF09430, IPR019008): Protein of unknown function (DUF2012) DUF2141 (PF09912, IPR018673): Uncharacterized protein conserved in bacteria (DUF2141) NikM (PF10670, IPR019613): Domain of unknown function (DUF4198) CarboxypepD_reg (PF13620): Carboxypeptidase regulatory-like domain SdrD_B (PF17210): SdrD B-like domain
84	NOMO2	interactor	1	0	0	DUF2012 (PF09430, IPR019008): Protein of unknown function (DUF2012) NikM (PF10670, IPR019613): Domain of unknown function (DUF4198) CarboxypepD_reg (PF13620): Carboxypeptidase regulatory-like domain fn3_3 (PF14686, IPR029413): Polysaccharide lyase family 4, domain II SdrD_B (PF17210): SdrD B-like domain
85	NSF	interactor	7	0.533	4.598	AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA) CDC48_2 (PF02933, IPR004201, SM01072): Cell division protein 48 (CDC48), domain 2 CDC48_N (PF02359, IPR003338, SM01073): Cell division protein 48 (CDC48), N-terminal domain ATPase (PF06745, IPR014774): KaiC AAA_19 (PF13245): Part of AAA domain
86	NTRK1	oncoprotein	56	0.128	1017.219	I-set (PF07679, IPR013098): Immunoglobulin I-set domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase LRR_8 (PF13855, IPR001611): Leucine rich repeat TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain
87	OTUD4	interactor	3	1.000	0	OTU (PF02338, IPR003323): OTU-like cysteine protease Presenilin (PF01080, IPR001108): Presenilin Peptidase_C65 (PF10275, IPR019400): Peptidase C65 Otubain
88	PAK2	protein found in more fusions	6	0.500	2.639	PBD (PF00786, IPR000095, SM00285): P21-Rho-binding domain Pkinase (PF00069, IPR000719): Protein kinase domain
89	PARP9	interactor	3	1.000	0	Macro (PF01661, IPR002589, SM00506): Macro domain PARP (PF00644, IPR012317): Poly(ADP-ribose) polymerase catalytic domain
90	PAWR	suppressor	12	0.576	14.074	ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16) PRKG1_interact (PF15898, IPR031775): cGMP-dependent protein kinase interacting domain
91	PDGFRA	oncoprotein	8	0.619	4.789	Herpes_gE (PF02480, IPR003404): Alphaherpesvirus glycoprotein E I-set (PF07679, IPR013098): Immunoglobulin I-set domain ig (PF00047, IPR013151, SM00409): Immunoglobulin domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase Ig_3 (PF13927): Immunoglobulin domain LAT (PF15234, IPR008359): Linker for activation of T-cells
92	PHGDH	interactor	9	0.611	4.732	2-Hacid_dh_C (PF02826, IPR006140): D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
93	PIAS1	suppressor	9	0.536	8.782	Herpes_capsid (PF06112, IPR009299): Gammaherpesvirus capsid protein zf-MIZ (PF02891, IPR004181): MIZ/SP-RING zinc finger PINIT (PF14324, IPR023321): PINIT domain UPF0544 (PF15749, IPR032739): Uncharacterised protein family UPF0544
94	PIK3CA	oncoprotein	4	0.500	1.267	PI3K_C2 (PF00792, IPR002420, SM00142): Phosphoinositide 3-kinase C2 PI3K_p85B (PF02192, IPR003113, SM00143): PI3-kinase family, p85-binding domain PI3K_rbd (PF00794, IPR000341, SM00144): PI3-kinase family, ras-binding domain PI3Ka (PF00613, IPR001263, SM00145): Phosphoinositide 3-kinase family, accessory domain (PIK domain) DUF2321 (PF10083, IPR016891): Uncharacterized protein conserved in bacteria (DUF2321) PI3_PI4_kinase (PF00454, IPR000403, SM00146): Phosphatidylinositol 3- and 4-kinase
95	PML	suppressor	20	0.433	41.483	zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger DUF3583 (PF12126, IPR021978): Protein of unknown function (DUF3583) zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
96	POR	interactor	4	0.667	1.500	FAD_binding_1 (PF00667, IPR003097): FAD binding domain Flavodoxin_1 (PF00258, IPR008254): Flavodoxin NAD_binding_1 (PF00175, IPR001433): Oxidoreductase NAD-binding domain
97	PPARA	suppressor	7	0.619	6.133	zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
98	PPARD	oncoprotein	11	0.533	11.655	zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
99	PPARG	suppressor	18	0.507	25.882	zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor PPARgamma_N (PF12577, IPR022590): PPAR gamma N-terminal region
100	PRKCD	suppressor	8	0.476	6.667	Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain)
101	PRKCE	suppressor	5	0.667	0.619	C2 (PF00168, IPR000008, SM00239): C2 domain Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain)
102	PRMT1	interactor	14	0.333	32.198	Methyltransf_25 (PF13649): Methyltransferase domain
103	PRMT3	interactor	9	0.444	12.656	PrmA (PF06325, IPR010456): Ribosomal protein L11 methyltransferase (PrmA) zf-C2H2_2 (PF12756, IPR015880): C2H2 type zinc-finger (2 copies)
104	PSMC3	interactor	8	0.476	7.567	AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA) DUF3713 (PF12506, IPR022186): Protein of unknown function (DUF3713) JIP_LZII (PF16471, IPR032486): JNK-interacting protein leucine zipper II
105	PTK2	protein found in more fusions	10	0.639	7.888	FERM_M (PF00373, IPR019748): FERM central domain Focal_AT (PF03623, IPR005189): Focal adhesion targeting region Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase UCMA (PF17085, IPR031386): Unique cartilage matrix associated protein
106	PTPA	suppressor	3	0.667	0.667	PTPA (PF03095, IPR004327): Phosphotyrosyl phosphate activator (PTPA) protein
107	PTPN2	suppressor	3	1.000	0	Synaptobrevin (PF00957, IPR001388): Synaptobrevin Y_phosphatase (PF00102, IPR000242, SM00194): Protein-tyrosine phosphatase
108	RACK1	suppressor	15	0.297	42.042	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
109	RELA	oncoprotein	23	0.385	68.633	DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region RHD_DNA_bind (PF00554, IPR011539): Rel homology DNA-binding domain RHD_dimer (PF16179, IPR032397): Rel homology dimerisation domain
110	RNF11	protein found in more fusions	3	1.000	0	zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain zf-ANAPC11 (PF12861, IPR024991): Anaphase-promoting complex subunit 11 RING-H2 finger
111	RPS6KB1	interactor	6	0.500	1.456	Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
112	RTF1	interactor	4	0.500	1.008	K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain OAD_gamma (PF04277, IPR005899): Oxaloacetate decarboxylase, gamma chain Plus-3 (PF03126, IPR004343): Plus-3 domain V_ATPase_I (PF01496, IPR002490): V-type ATPase 116kDa subunit family YL1 (PF05764, IPR008895): YL1 nuclear protein AAA_23 (PF13476): AAA domain DUF4407 (PF14362, IPR025519): Domain of unknown function (DUF4407) IMUP (PF15761, IPR026621): Immortalisation up-regulated protein
113	RXRA	oncoprotein	15	0.484	18.942	zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor Nuc_recep-AF1 (PF11825, IPR021780): Nuclear/hormone receptor activator site AF-1
114	SARS	interactor	7	0.667	3.717	NOD (PF06816, IPR010660): NOTCH protein Seryl_tRNA_N (PF02403, IPR015866): Seryl-tRNA synthetase N-terminal domain tRNA-synt_2b (PF00587, IPR002314): tRNA synthetase class II core domain (G, H, P, S and T)
115	SHANK1	interactor	3	1.000	0	Herpes_PAP (PF03325, IPR004997): Herpesvirus polymerase accessory protein PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) SAM_1 (PF00536, IPR021129, SM00454): SAM domain (Sterile alpha motif) SH3_2 (PF07653, IPR011511): Variant SH3 domain Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) FERM_f0 (PF16511, IPR032425): N-terminal or F0 domain of Talin-head FERM RSRP (PF17069): Arginine/Serine-Rich protein 1
116	SHMT1	interactor	12	0.709	5.301	SHMT (PF00464, IPR001085): Serine hydroxymethyltransferase
117	SHMT2	interactor	25	0.267	162.676	SHMT (PF00464, IPR001085): Serine hydroxymethyltransferase
118	SMARCA2	suppressor	7	0.905	0.321	DUF1168 (PF06658, IPR009548): Protein of unknown function (DUF1168) DUF1840 (PF08895, IPR014991): Domain of unknown function (DUF1840) HSA (PF07529, IPR014012, SM00573): HSA QLQ (PF08880, IPR014978, SM00951): QLQ SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain YL1 (PF05764, IPR008895): YL1 nuclear protein BRK (PF07533, IPR006576, SM00592): BRK domain DUF2052 (PF09747, IPR018613): Coiled-coil domain containing protein (DUF2052) EPL1 (PF10513, IPR019542): Enhancer of polycomb-like Bromodomain (PF00439, IPR001487, SM00297): Bromodomain Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain SnAC (PF14619, IPR029295): Snf2-ATP coupling, chromatin remodelling complex WRNPLPNID (PF15017): Putative WW-binding domain and destruction box
119	SMARCA4	suppressor	20	0.347	65.469	DUF1840 (PF08895, IPR014991): Domain of unknown function (DUF1840) HSA (PF07529, IPR014012, SM00573): HSA QLQ (PF08880, IPR014978, SM00951): QLQ SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain BRK (PF07533, IPR006576, SM00592): BRK domain Bromodomain (PF00439, IPR001487, SM00297): Bromodomain Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal DUF4065 (PF13274, IPR025272): Protein of unknown function (DUF4065) SnAC (PF14619, IPR029295): Snf2-ATP coupling, chromatin remodelling complex WRNPLPNID (PF15017): Putative WW-binding domain and destruction box
120	SMURF1	interactor	12	0.236	27.701	C2 (PF00168, IPR000008, SM00239): C2 domain WW (PF00397, IPR001202, SM00456): WW domain HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
121	SNX1	protein found in more fusions	13	0.652	8.368	PX (PF00787, IPR001683, SM00312): PX domain Sorting_nexin (PF03700, IPR005329): Sorting nexin, N-terminal domain Vps5 (PF09325, IPR015404): Vps5 C terminal like
122	SNX2	interactor	18	0.392	56.230	PX (PF00787, IPR001683, SM00312): PX domain Sorting_nexin (PF03700, IPR005329): Sorting nexin, N-terminal domain Vps5 (PF09325, IPR015404): Vps5 C terminal like
123	SNX6	interactor	15	0.400	41.260	PX (PF00787, IPR001683, SM00312): PX domain Vps5 (PF09325, IPR015404): Vps5 C terminal like
124	SPACA1	interactor	1	0	0	DUF912 (PF06024, IPR009261): Nucleopolyhedrovirus protein of unknown function (DUF912) PRIMA1 (PF16101): Proline-rich membrane anchor 1
125	SPTAN1	oncoprotein	13	0.333	43.208	EFhand_Ca_insen (PF08726, IPR014837): Ca2+ insensitive EF hand Spectrin (PF00435, IPR002017): Spectrin repeat SH3_1 (PF00018, IPR001452, SM00326): SH3 domain Tetrabrachion (PF11401, IPR021535): Tetrabrachion EF-hand_7 (PF13499, IPR011992): EF-hand domain pair E2F_CC-MB (PF16421, IPR032198): E2F transcription factor CC-MB domain
126	SPTB	interactor	2	1.000	0	CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain Com_YlbF (PF06133, IPR010368): Control of competence regulator ComK, YlbF/YmcA Spectrin (PF00435, IPR002017): Spectrin repeat PH_9 (PF15410): Pleckstrin homology domain
127	SPTBN1	suppressor	7	0.571	4.675	CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain COG2 (PF06148, IPR024602): COG (conserved oligomeric Golgi) complex component, COG2 DUF1764 (PF08576, IPR013885): Eukaryotic protein of unknown function (DUF1764) Spectrin (PF00435, IPR002017): Spectrin repeat PH_9 (PF15410): Pleckstrin homology domain
128	SRC	oncoprotein	22	0.233	113.991	Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
129	STAT2	oncoprotein	9	0.472	8.879	SH2 (PF00017, IPR000980, SM00252): SH2 domain STAT_alpha (PF01017, IPR013800): STAT protein, all-alpha domain STAT_bind (PF02864, IPR013801): STAT protein, DNA binding domain STAT_int (PF02865, IPR013799, SM00964): STAT protein, protein interaction domain STAT2_C (PF12188, IPR022756): Signal transducer and activator of transcription 2 C terminal
130	STAT3	suppressor	36	0.218	325.462	SH2 (PF00017, IPR000980, SM00252): SH2 domain STAT_alpha (PF01017, IPR013800): STAT protein, all-alpha domain STAT_bind (PF02864, IPR013801): STAT protein, DNA binding domain STAT_int (PF02865, IPR013799, SM00964): STAT protein, protein interaction domain
131	STAT5A	suppressor	14	0.397	23.706	SH2 (PF00017, IPR000980, SM00252): SH2 domain STAT_alpha (PF01017, IPR013800): STAT protein, all-alpha domain STAT_bind (PF02864, IPR013801): STAT protein, DNA binding domain STAT_int (PF02865, IPR013799, SM00964): STAT protein, protein interaction domain
132	TBCD	interactor	9	0.500	9.402	HEAT (PF02985, IPR000357): HEAT repeat HEAT_PBS (PF03130, IPR004155, SM00567): PBS lyase HEAT-like repeat TFCD_C (PF12612, IPR022577): Tubulin folding cofactor D C terminal HEAT_EZ (PF13513): HEAT-like repeat
133	TEX264	interactor	1	0	0	NA
134	TNFRSF1A	oncoprotein	11	0.289	23.834	Death (PF00531, IPR000488, SM00005): Death domain TNFR_c6 (PF00020, IPR001368, SM00208): TNFR/NGFR cysteine-rich region
135	TRADD	interactor	4	0.667	0.500	Death (PF00531, IPR000488, SM00005): Death domain TRADD_N (PF09034, IPR009095): TRADD, N-terminal domain TPR_14 (PF13428): Tetratricopeptide repeat
136	TRIM28	protein found in more fusions	20	0.263	83.480	ASFV_J13L (PF05568, IPR008385): African swine fever virus J13L protein K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain PHD (PF00628, IPR019787, SM00249): PHD-finger FYVE_2 (PF02318, IPR010911): FYVE-type zinc finger zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger zf-RING_5 (PF14634, IPR001841): zinc-RING finger domain SKA2 (PF16740, IPR026762): Spindle and kinetochore-associated protein 2
137	TSNAX	interactor	6	0.333	7.067	Translin (PF01997, IPR002848): Translin family
138	TYK2	interactor	8	0.476	4.219	Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
139	U2AF2	protein found in more fusions	12	0.600	8.309	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Transformer (PF06495, IPR010519): Fruit fly transformer protein
140	UBE2I	interactor	27	0.228	173.483	UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
141	USP13	interactor	2	1.000	0	UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase zf-UBP (PF02148, IPR001607, SM00290): Zn-finger in ubiquitin-hydrolases and other protein
142	VCP	protein found in more fusions	23	0.212	138.610	AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA) CDC48_2 (PF02933, IPR004201, SM01072): Cell division protein 48 (CDC48), domain 2 CDC48_N (PF02359, IPR003338, SM01073): Cell division protein 48 (CDC48), N-terminal domain TniB (PF05621, IPR008868): Bacterial TniB protein Vps4_C (PF09336, IPR015415): Vps4 C terminal oligomerisation domain DUF3944 (PF13099, IPR025217): Domain of unknown function (DUF3944)
143	VDR	suppressor	11	0.556	9.781	zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
144	VPS26A	protein found in more fusions	12	0.473	16.836	Vps26 (PF03643, IPR005377): Vacuolar protein sorting-associated protein 26
145	VPS29	interactor	11	0.527	13.517	Metallophos_2 (PF12850, IPR024654): Calcineurin-like phosphoesterase superfamily domain
146	XPO1	interactor	29	0.170	255.043	CRM1_C (PF08767, IPR014877, SM01102): CRM1 C terminal Hydrolase_3 (PF08282, IPR023214): haloacid dehalogenase-like hydrolase IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain Xpo1 (PF08389, IPR013598): Exportin 1-like protein Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region
147	YAP1	suppressor	10	0.289	22.687	Bindin (PF02084, IPR000775): Bindin WW (PF00397, IPR001202, SM00456): WW domain GspL_C (PF12693, IPR025691): GspL periplasmic domain FAM181 (PF15238, IPR029359): FAM181

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