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Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

Powered by Cytoscape Web for: parental proteins SSNA1 (from a repository: Thu Nov 10 14:59:26 2016)
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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)16
The number (and %) of the onco-proteins4 (25.00 %)
The number (and %) of the tumor suppressors0 (0.00 %)
Total number of binary PPIs (saturation %)23 (19.17 %)
The number (and %) of affected PPIs16 (69.57 %)
The number of possible different fusions5
PPI diameter2
PPI radius1
The average degree of PPI2.125
Assortativity coefficient-0.4944
The network average Clustering coefficient0.251
The number (and %) of a zero Clustering coefficients11 (68.75 %)
The number (and %) of a zero Betweenness Centrality15 (93.75 %)

ACTIVE INTERACTORS


List of the fusions

PPI for parental proteins: SSNA1 All fusions
: BG222117;
Proteins found in more fusions CTBP1 (see 2 fusions); ITPA (see 1 fusions); GOPC (see 2 fusions); SSNA1 (see 1 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 SSNA1parental protein160.019206.000APG6 (PF04111, IPR007243): Autophagy protein Apg6
Fzo_mitofusin (PF04799, IPR006884): fzo-like conserved region
2 ANXA3interactor100Annexin (PF00191, IPR018502, SM00335): Annexin
RPT (PF13446, IPR025305): A repeated domain in UCH-protein
3 CTBP1protein found in more fusions31.00002-Hacid_dh_C (PF02826, IPR006140): D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
Cellsynth_D (PF03500, IPR022798): Cellulose synthase subunit D
4 EHHADHinteractor1002-Hacid_dh_C (PF02826, IPR006140): D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
3HCDH (PF00725, IPR006108): 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain
3HCDH_N (PF02737, IPR006176): 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain
ECH_1 (PF00378, IPR001753): Enoyl-CoA hydratase/isomerase
5 GOPConcoprotein200DUF903 (PF06004, IPR010305): Bacterial protein of unknown function (DUF903)
HALZ (PF02183, IPR003106, SM00340): Homeobox associated leucine zipper
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
bZIP_2 (PF07716, IPR004827, SM00338): Basic region leucine zipper
DUF3209 (PF11483, IPR021577): Protein of unknown function (DUF3209)
6 ITPAprotein found in more fusions200Ham1p_like (PF01725, IPR002637): Ham1 family
7 LNX1interactor31.0000PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
zf-rbx1 (PF12678, IPR024766): RING-H2 zinc finger domain
zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
8 MED4interactor21.0000Med4 (PF10018, IPR019258): Vitamin-D-receptor interacting Mediator subunit 4
9 PGLSinteractor100Glucosamine_iso (PF01182, IPR006148): Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase
10 POLR2Minteractor100GCOM2 (PF15328, IPR026213): Putative GRINL1B complex locus protein 2
11 SDCBPinteractor21.0000PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
12 SPATA2interactor100zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger
13 SRIoncoprotein200EF-hand_1 (PF00036, IPR002048, SM00054): EF hand
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
EF-hand_8 (PF13833, IPR002048): EF-hand domain pair
14 TBC1D7interactor100RabGAP-TBC (PF00566, IPR000195, SM00164): Rab-GTPase-TBC domain
15 TCEANCinteractor100Ribosomal_L37e (PF01907, IPR001569): Ribosomal protein L37e
Med26 (PF08711, IPR017923): TFIIS helical bundle-like domain
TFIIS_C (PF01096, IPR001222): Transcription factor S-II (TFIIS)
TFIIS_M (PF07500, IPR003618): Transcription factor S-II (TFIIS), central domain
16 TXN2interactor100Thioredoxin (PF00085, IPR013766): Thioredoxin

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