1 |
SRSF2 | parental protein | 109 | 0.126 | 6212.218 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TP2 (PF01254, IPR000678): Nuclear transition protein 2 Transformer (PF06495, IPR010519): Fruit fly transformer protein Apt1 (PF10351, IPR019443): Golgi-body localisation protein domain DUF2457 (PF10446, IPR018853): Protein of unknown function (DUF2457) |
2 |
ACBD3 | interactor | 3 | 1.000 | 0 | ACBP (PF00887, IPR000582): Acyl CoA binding protein CDC45 (PF02724, IPR003874): CDC45-like protein TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit GOLD_2 (PF13897, IPR009038): Golgi-dynamics membrane-trafficking NINJA_B (PF16136, IPR032310): Putative nuclear localisation signal |
3 |
AIRE | interactor | 7 | 0.533 | 1.668 | PHD (PF00628, IPR019787, SM00249): PHD-finger SAND (PF01342, IPR000770, SM00258): SAND domain HSR (PF03172, IPR004865): HSR domain; Sp100 domain zf-PHD-like (PF15446): PHD/FYVE-zinc-finger like domain |
4 |
ALYREF | interactor | 23 | 0.554 | 20.141 | FYTT (PF07078, IPR009782): Forty-two-three protein RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 |
5 |
ATP6V1F | interactor | 4 | 0.500 | 2.667 | ATP-synt_F (PF01990, IPR008218): ATP synthase (F/14-kDa) subunit |
6 |
BAG6 | interactor | 8 | 0.381 | 10.000 | DUF1179 (PF06678, IPR009564): Protein of unknown function (DUF1179) Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family DUF2939 (PF11159, IPR021330): Protein of unknown function (DUF2939) DUF3538 (PF12057, IPR021925): Domain of unknown function (DUF3538) PRIMA1 (PF16101): Proline-rich membrane anchor 1 |
7 |
BARD1 | suppressor | 18 | 0.471 | 27.465 | BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_5 (PF13857): Ankyrin repeats (many copies) zf-RING_6 (PF14835): zf-RING of BARD1-type protein BRCT_2 (PF16589, IPR001357): BRCT domain, a BRCA1 C-terminus domain |
8 |
BTF3 | interactor | 5 | 0.400 | 4.833 | NAC (PF01849, IPR002715): NAC domain |
9 |
CAND1 | interactor | 35 | 0.496 | 69.424 | Adaptin_N (PF01602, IPR002553): Adaptin N terminal region DUF1981 (PF09324, IPR015403): Domain of unknown function (DUF1981) HEAT (PF02985, IPR000357): HEAT repeat TIP120 (PF08623, IPR013932): TATA-binding protein interacting (TIP20) RTP1_C1 (PF10363, IPR019451): Required for nuclear transport of RNA pol II C-terminus 1 DUF3385 (PF11865, IPR024585): Domain of unknown function (DUF3385) MMS19_C (PF12460, IPR024687): RNAPII transcription regulator C-terminal Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region HEAT_EZ (PF13513): HEAT-like repeat HEAT_2 (PF13646): HEAT repeats MMS19_N (PF14500): Dos2-interacting transcription regulator of RNA-Pol-II |
10 |
CCT5 | interactor | 11 | 0.600 | 8.421 | Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family |
11 |
CDC5L | interactor | 29 | 0.476 | 59.217 | OmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like) Pox_A_type_inc (PF04508, IPR007596): Viral A-type inclusion protein repeat Cir_N (PF10197, IPR019339, SM01083): N-terminal domain of CBF1 interacting co-repressor CIR Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain Myb_Cef (PF11831, IPR021786): pre-mRNA splicing factor component Myb_DNA-bind_6 (PF13921): Myb-like DNA-binding domain |
12 |
CDK6 | suppressor | 7 | 0.667 | 2.376 | Pkinase (PF00069, IPR000719): Protein kinase domain |
13 |
CEP128 | interactor | 14 | 0.341 | 42.986 | DUF1129 (PF06570, IPR009214): Protein of unknown function (DUF1129) DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664) ERM (PF00769, IPR011259): Ezrin/radixin/moesin family Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein SpoOE-like (PF09388, IPR018540): Spo0E like sporulation regulatory protein DUF2968 (PF11180, IPR021350): Protein of unknown function (DUF2968) TraF_2 (PF13729, IPR032811): F plasmid transfer operon, TraF, protein GAS (PF13851, IPR025593): Growth-arrest specific micro-tubule binding DUF4200 (PF13863, IPR025252): Domain of unknown function (DUF4200) DUF4404 (PF14357, IPR025516): Domain of unknown function (DUF4404) HAUS6_N (PF14661, IPR028163): HAUS augmin-like complex subunit 6 N-terminus HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1 |
14 |
CEP164 | interactor | 6 | 0.467 | 6.167 | DUF883 (PF05957, IPR010279): Bacterial protein of unknown function (DUF883) DUF948 (PF06103, IPR009293): Bacterial protein of unknown function (DUF948) TBPIP (PF07106, IPR010776): Tat binding protein 1(TBP-1)-interacting protein (TBPIP) WW (PF00397, IPR001202, SM00456): WW domain KxDL (PF10241, IPR019371): Uncharacterized conserved protein XhlA (PF10779, IPR019715): Haemolysin XhlA KfrA_N (PF11740, IPR021104): Plasmid replication region DNA-binding N-term DUF3807 (PF12720, IPR024526): Protein of unknown function (DUF3807) |
15 |
CEP72 | interactor | 7 | 0.524 | 7.352 | LRR_9 (PF14580): Leucine-rich repeat FAM76 (PF16046, IPR032017): FAM76 protein |
16 |
CIR1 | interactor | 4 | 1.000 | 0 | DUF755 (PF05501, IPR008474): Domain of unknown function (DUF755) EVI2A (PF05399, IPR008608): Ectropic viral integration site 2A protein (EVI2A) Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4 IncA (PF04156, IPR007285): IncA protein Cir_N (PF10197, IPR019339, SM01083): N-terminal domain of CBF1 interacting co-repressor CIR YebO (PF13974, IPR025594): YebO-like protein CSRNP_N (PF16019, IPR031972): Cysteine/serine-rich nuclear protein N-terminus |
17 |
CNTRL | oncoprotein | 5 | 0.700 | 2.333 | APG6 (PF04111, IPR007243): Autophagy protein Apg6 BcrAD_BadFG (PF01869, IPR002731): BadF/BadG/BcrA/BcrD ATPase family DUF724 (PF05266, IPR007930): Protein of unknown function (DUF724) DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972) Fez1 (PF06818): Fez1 Laminin_II (PF06009, IPR010307): Laminin Domain II Ly49 (PF08391, IPR013600): Ly49-like protein, N-terminal region Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein Syntaxin-6_N (PF09177, IPR015260): Syntaxin 6, N-terminal TBPIP (PF07106, IPR010776): Tat binding protein 1(TBP-1)-interacting protein (TBPIP) TMPIT (PF07851, IPR012926): TMPIT-like protein TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein Uso1_p115_C (PF04871, IPR006955): Uso1 / p115 like vesicle tethering protein, C terminal region Golgin_A5 (PF09787, IPR019177): Golgin subfamily A member 5 DUF2968 (PF11180, IPR021350): Protein of unknown function (DUF2968) LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies) DUF4407 (PF14362, IPR025519): Domain of unknown function (DUF4407) LRR_9 (PF14580): Leucine-rich repeat |
18 |
COPE | interactor | 8 | 0.429 | 5.764 | Coatomer_E (PF04733, IPR006822): Coatomer epsilon subunit TPR_19 (PF14559): Tetratricopeptide repeat |
19 |
COPS5 | protein found in more fusions | 28 | 0.547 | 39.446 | JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease |
20 |
CSNK2A1 | oncoprotein | 19 | 0.412 | 30.503 | Pkinase (PF00069, IPR000719): Protein kinase domain |
21 |
CUL1 | suppressor | 33 | 0.490 | 68.732 | Cullin (PF00888, IPR001373, SM00182): Cullin family Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain |
22 |
CUL2 | suppressor | 22 | 0.554 | 25.150 | Cullin (PF00888, IPR001373, SM00182): Cullin family Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain |
23 |
CUL3 | protein found in more fusions | 46 | 0.360 | 294.101 | Cullin (PF00888, IPR001373, SM00182): Cullin family Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain WAC_Acf1_DNA_bd (PF10537, IPR013136): ATP-utilising chromatin assembly and remodelling N-terminal |
24 |
CUL5 | suppressor | 19 | 0.626 | 24.317 | Cullin (PF00888, IPR001373, SM00182): Cullin family GlutR_dimer (PF00745, IPR015896): Glutamyl-tRNAGlu reductase, dimerisation domain Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain |
25 |
DCTN1 | interactor | 9 | 0.536 | 10.554 | Bap31 (PF05529, IPR008417): B-cell receptor-associated protein 31-like CAP_GLY (PF01302, IPR000938, SM01052): CAP-Gly domain FlgN (PF05130, IPR007809): FlgN protein HOOK (PF05622, IPR008636): HOOK protein SlyX (PF04102, IPR007236): SlyX TSC22 (PF01166, IPR000580): TSC-22/dip/bun family DUF2443 (PF10398, IPR019469): Protein of unknown function (DUF2443) ADIP (PF11559, IPR021622): Afadin- and alpha -actinin-Binding TMF_DNA_bd (PF12329, IPR022092): TATA element modulatory factor 1 DNA binding Dynactin (PF12455, IPR022157): Dynein associated protein Lebercilin (PF15619, IPR028933): Ciliary protein causing Leber congenital amaurosis disease KELK (PF15796, IPR031597): KELK-motif containing domain of MRCK Ser/Thr protein kinase |
26 |
DEK | oncoprotein | 11 | 0.418 | 7.667 | DEK_C (PF08766, IPR014876): DEK C terminal domain Prothymosin (PF03247, IPR004931): Prothymosin/parathymosin family SAP (PF02037, IPR003034, SM00513): SAP domain Bud13 (PF09736, IPR018609): Pre-mRNA-splicing factor of RES complex DUF2052 (PF09747, IPR018613): Coiled-coil domain containing protein (DUF2052) TFIIE-A_C (PF11521, IPR021600): C-terminal general transcription factor TFIIE alpha PBP1_TM (PF14812, IPR032730): Transmembrane domain of transglycosylase PBP1 at N-terminal |
27 |
DSTN | interactor | 5 | 0.400 | 5.667 | Cofilin_ADF (PF00241, IPR002108, SM00102): Cofilin/tropomyosin-type actin-binding protein |
28 |
EED | suppressor | 20 | 0.468 | 31.419 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160 ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain |
29 |
EIF4A3 | interactor | 27 | 0.618 | 21.848 | DEAD (PF00270, IPR011545): DEAD/DEAH box helicase Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain |
30 |
EIF5 | interactor | 5 | 1.000 | 0 | CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal Hist_rich_Ca-bd (PF10529, IPR019552): Histidine-rich Calcium-binding repeat region eIF-5_eIF-2B (PF01873, IPR002735, SM00653): Domain found in IF2B/IF5 W2 (PF02020, IPR003307, SM00515): eIF4-gamma/eIF5/eIF2-epsilon |
31 |
ESR1 | suppressor | 27 | 0.348 | 110.356 | Oest_recep (PF02159, IPR001292): Oestrogen receptor zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor ESR1_C (PF12743, IPR024736): Oestrogen-type nuclear receptor final C-terminal |
32 |
EWSR1 | oncoprotein | 34 | 0.403 | 142.420 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SVS_QK (PF10578, IPR018942): Seminal vesicle protein repeat zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 Keratin_2_head (PF16208, IPR032444): Keratin type II head |
33 |
FBF1 | interactor | 13 | 0.269 | 35.667 | DUF737 (PF05300, IPR007964): Protein of unknown function (DUF737) OmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like) Sacchrp_dh_NADP (PF03435, IPR005097): Saccharopine dehydrogenase NADP binding domain Spc24 (PF08286, IPR013252): Spc24 subunit of Ndc80 Atg14 (PF10186, IPR018791): Vacuolar sorting 38 and autophagy-related subunit 14 Dynamin_N (PF00350, IPR001401, SM00053): Dynamin family YlqD (PF11068, IPR021297): YlqD protein KfrA_N (PF11740, IPR021104): Plasmid replication region DNA-binding N-term |
34 |
FGFR1OP | oncoprotein | 9 | 0.429 | 11.900 | FOP_dimer (PF09398, IPR018993): FOP N terminal dimerisation domain |
35 |
GOLGA2 | interactor | 12 | 0.348 | 15.850 | ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16) Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein Rootletin (PF15035): Ciliary rootlet component, centrosome cohesion GOLGA2L5 (PF15070, IPR024858): Putative golgin subfamily A member 2-like protein 5 |
36 |
HDGF | interactor | 18 | 0.438 | 30.716 | PWWP (PF00855, IPR000313, SM00293): PWWP domain |
37 |
HNRNPA2B1 | oncoprotein | 29 | 0.426 | 87.213 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
38 |
HNRNPDL | interactor | 21 | 0.586 | 23.653 | CBFNT (PF08143, IPR012956): CBFNT (NUC161) domain RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
39 |
HSPA1A | interactor | 19 | 0.386 | 53.951 | HSP70 (PF00012, IPR013126): Hsp70 protein |
40 |
HUWE1 | oncoprotein | 22 | 0.424 | 50.544 | BUD22 (PF09073, IPR015158): BUD22 DUF908 (PF06012, IPR010309): Domain of Unknown Function (DUF908) DUF913 (PF06025, IPR010314): Domain of Unknown Function (DUF913) FdhE (PF04216, IPR006452): Protein involved in formate dehydrogenase formation HABP4_PAI-RBP1 (PF04774, IPR006861): Hyaluronan / mRNA binding family Ku_C (PF03730, IPR005160): Ku70/Ku80 C-terminal arm Merozoite_SPAM (PF07133, IPR010784): Merozoite surface protein (SPAM) Mucin (PF01456, IPR000458): Mucin-like glycoprotein Nop14 (PF04147, IPR007276): Nop14-like family PBP_sp32 (PF07222, IPR009865): Proacrosin binding protein sp32 RNA_pol_Rpc4 (PF05132, IPR007811): RNA polymerase III RPC4 TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain WWE (PF02825, IPR004170, SM00678): WWE domain HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase) Tim54 (PF11711, IPR021056): Inner membrane protein import complex subunit Tim54 U1snRNP70_N (PF12220, IPR022023): U1 small nuclear ribonucleoprotein of 70kDa MW N terminal DUF4414 (PF14377, IPR025527): Domain of unknown function (DUF4414) |
41 |
KAT5 | suppressor | 11 | 0.378 | 14.956 | MOZ_SAS (PF01853, IPR002717): MOZ/SAS family Tudor-knot (PF11717, IPR025995): RNA binding activity-knot of a chromodomain |
42 |
KATNA1 | interactor | 4 | 0.833 | 0.154 | AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA) ABC_tran (PF00005, IPR003439): ABC transporter Vps4_C (PF09336, IPR015415): Vps4 C terminal oligomerisation domain TPR_8 (PF13181, IPR019734): Tetratricopeptide repeat AAA_22 (PF13401, IPR003593): AAA domain |
43 |
KRT31 | interactor | 4 | 0.667 | 0.536 | Filament (PF00038, IPR001664): Intermediate filament protein |
44 |
KRT40 | interactor | 7 | 0.381 | 4.812 | Filament (PF00038, IPR001664): Intermediate filament protein UPF0184 (PF03670, IPR022788): Uncharacterised protein family (UPF0184) |
45 |
LIG4 | interactor | 2 | 1.000 | 0 | APG17 (PF04108, IPR007240): Autophagy protein Apg17 BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain DNA_ligase_A_C (PF04679, IPR012309): ATP dependent DNA ligase C terminal region DNA_ligase_A_M (PF01068, IPR012310): ATP dependent DNA ligase domain DNA_ligase_A_N (PF04675, IPR012308): DNA ligase N terminus DNA_ligase_IV (PF11411, IPR021536): DNA ligase IV RTT107_BRCT_5 (PF16770, IPR001357): Regulator of Ty1 transposition protein 107 BRCT domain |
46 |
LZTS2 | suppressor | 8 | 0.321 | 9.121 | CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal DUF1127 (PF06568, IPR009506): Domain of unknown function (DUF1127) Fez1 (PF06818): Fez1 ADIP (PF11559, IPR021622): Afadin- and alpha -actinin-Binding DUF4250 (PF14056, IPR025346): Domain of unknown function (DUF4250) |
47 |
MAGOH | interactor | 18 | 0.523 | 15.435 | Mago_nashi (PF02792, IPR004023): Mago nashi protein |
48 |
MYO1C | interactor | 5 | 0.400 | 3.126 | IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif Myosin_TH1 (PF06017, IPR010926): Unconventional myosin tail, actin- and lipid-binding Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain) |
49 |
NCF1 | interactor | 2 | 0 | 0 | p47_phox_C (PF08944, IPR015039): NADPH oxidase subunit p47Phox, C terminal domain PX (PF00787, IPR001683, SM00312): PX domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain NECFESHC (PF16621, IPR032136): SH3 terminal domain of 2nd SH3 on Neutrophil cytosol factor 1 |
50 |
NEDD8 | interactor | 18 | 0.471 | 38.641 | ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family |
51 |
NPHP1 | interactor | 6 | 0.600 | 2.833 | SH3_1 (PF00018, IPR001452, SM00326): SH3 domain FAM176 (PF14851): FAM176 family Speriolin_N (PF15058, IPR029385): Speriolin N terminus DUF4746 (PF15928, IPR031827): Domain of unknown function (DUF4746) |
52 |
NTRK1 | oncoprotein | 54 | 0.242 | 617.047 | I-set (PF07679, IPR013098): Immunoglobulin I-set domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase LRR_8 (PF13855, IPR001611): Leucine rich repeat TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain |
53 |
NUBP2 | interactor | 4 | 0.500 | 2.333 | ParA (PF10609, IPR019591): NUBPL iron-transfer P-loop NTPase |
54 |
NUDCD2 | interactor | 1 | 0 | 0 | CS (PF04969, IPR007052): CS domain DUF3110 (PF11360, IPR021503): Protein of unknown function (DUF3110) |
55 |
NXF1 | interactor | 34 | 0.322 | 188.254 | NTF2 (PF02136, IPR002075): Nuclear transport factor 2 (NTF2) domain Tap-RNA_bind (PF09162, IPR015245): Tap, RNA-binding TAP_C (PF03943, IPR005637, SM00804): TAP C-terminal domain LRR_8 (PF13855, IPR001611): Leucine rich repeat |
56 |
OBSL1 | interactor | 28 | 0.447 | 45.582 | BiPBP_C (PF06832, IPR009647): Penicillin-Binding Protein C-terminus Family fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain Herpes_gE (PF02480, IPR003404): Alphaherpesvirus glycoprotein E I-set (PF07679, IPR013098): Immunoglobulin I-set domain V-set (PF07686, IPR013106): Immunoglobulin V-set domain Ig_3 (PF13927): Immunoglobulin domain Ig_4 (PF16680, IPR032052): T-cell surface glycoprotein CD3 delta chain Izumo-Ig (PF16706, IPR032699): Izumo-like Immunoglobulin domain |
57 |
OFD1 | protein found in more fusions | 15 | 0.297 | 49.652 | APG6 (PF04111, IPR007243): Autophagy protein Apg6 Exonuc_VII_L (PF02601, IPR020579): Exonuclease VII, large subunit GrpE (PF01025, IPR000740): GrpE NPV_P10 (PF05531, IPR008702): Nucleopolyhedrovirus P10 protein XhlA (PF10779, IPR019715): Haemolysin XhlA DUF3372 (PF11852, IPR024561): Domain of unknown function (DUF3372) LisH_2 (PF16045, IPR006594): LisH |
58 |
PARK2 | suppressor | 19 | 0.359 | 47.280 | IBR (PF01485, IPR002867, SM00647): IBR domain, a half RING-finger domain ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family |
59 |
PAXIP1 | interactor | 12 | 0.455 | 9.974 | BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain IPT (PF01745, IPR002648, SM00429): Isopentenyl transferase SURF6 (PF04935, IPR007019): Surfeit locus protein 6 DUF2052 (PF09747, IPR018613): Coiled-coil domain containing protein (DUF2052) CYSTM (PF12734, IPR028144): Cysteine-rich TM module stress tolerance PTCB-BRCT (PF12738, IPR001357): twin BRCT domain BRCT_2 (PF16589, IPR001357): BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT (PF16759, IPR031916): DNA ligase 3 BRCT domain RTT107_BRCT_5 (PF16770, IPR001357): Regulator of Ty1 transposition protein 107 BRCT domain |
60 |
POC1B | interactor | 3 | 0.667 | 1.000 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain |
61 |
POC5 | interactor | 6 | 0.533 | 5.400 | vATP-synt_E (PF01991, IPR002842): ATP synthase (E/31 kDa) subunit Kinetocho_Slk19 (PF12709, IPR024312): Central kinetochore-associated IMUP (PF15761, IPR026621): Immortalisation up-regulated protein CC2-LZ (PF16516, IPR032419): Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator |
62 |
POLR2A | protein found in more fusions | 22 | 0.329 | 66.919 | RNA_pol_Rpb1_1 (PF04997, IPR007080): RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 (PF00623, IPR000722): RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 (PF04983, IPR007066): RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 (PF05000, IPR007083): RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_5 (PF04998, IPR007081): RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_R (PF05001, IPR000684): RNA polymerase Rpb1 C-terminal repeat |
63 |
PPARGC1A | interactor | 5 | 0.500 | 1.882 | Pap_E4 (PF02711, IPR003861): E4 protein RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RSRP (PF17069): Arginine/Serine-Rich protein 1 |
64 |
PSMA1 | interactor | 22 | 0.248 | 110.577 | Proteasome (PF00227, IPR001353): Proteasome subunit Proteasome_A_N (PF10584, IPR000426, SM00948): Proteasome subunit A N-terminal signature |
65 |
PSMA5 | oncoprotein | 16 | 0.517 | 23.784 | Proteasome (PF00227, IPR001353): Proteasome subunit Proteasome_A_N (PF10584, IPR000426, SM00948): Proteasome subunit A N-terminal signature |
66 |
PSMB1 | interactor | 9 | 0.556 | 9.058 | Proteasome (PF00227, IPR001353): Proteasome subunit |
67 |
PSME3 | protein found in more fusions | 12 | 0.418 | 14.376 | PA28_alpha (PF02251, IPR003185): Proteasome activator pa28 alpha subunit PA28_beta (PF02252, IPR003186): Proteasome activator pa28 beta subunit |
68 |
PTMA | oncoprotein | 8 | 0.250 | 16.233 | Prothymosin (PF03247, IPR004931): Prothymosin/parathymosin family |
69 |
RAD23A | oncoprotein | 9 | 0.536 | 8.152 | UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain XPC-binding (PF09280, IPR015360): XPC-binding domain ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family |
70 |
RNPS1 | interactor | 26 | 0.505 | 52.671 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2457 (PF10446, IPR018853): Protein of unknown function (DUF2457) Macoilin (PF09726, IPR019130): Transmembrane protein |
71 |
RPGRIP1L | interactor | 9 | 0.389 | 15.467 | bZIP_1 (PF00170, IPR004827): bZIP transcription factor C2 (PF00168, IPR000008, SM00239): C2 domain DivIC (PF04977, IPR007060): Septum formation initiator DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664) FtsL (PF04999, IPR011922): Cell division protein FtsL T3SS_needle_F (PF09392, IPR021123): Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF CENP-F_leu_zip (PF10473, IPR019513): Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 C2-C2_1 (PF11618, IPR021656): First C2 domain of RPGR-interacting protein 1 BNIP2 (PF12496, IPR022181): Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 DUF4200 (PF13863, IPR025252): Domain of unknown function (DUF4200) DUF4497 (PF14924): Protein of unknown function (DUF4497) |
72 |
RUVBL1 | oncoprotein | 21 | 0.453 | 33.906 | TIP49 (PF06068, IPR010339): TIP49 C-terminus |
73 |
SASS6 | interactor | 3 | 1.000 | 0 | CALCOCO1 (PF07888, IPR012852): Calcium binding and coiled-coil domain (CALCOCO1) like Tropomyosin_1 (PF12718, IPR000533): Tropomyosin like PI3K_P85_iSH2 (PF16454, IPR032498): Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain SAS-6_N (PF16531, IPR032396): Centriolar protein SAS N-terminal |
74 |
SBNO1 | oncoprotein | 3 | 0.667 | 0.222 | Helicase_C_4 (PF13871, IPR026937): C-terminal domain on Strawberry notch homologue AAA_34 (PF13872): P-loop containing NTP hydrolase pore-1 |
75 |
SCLT1 | oncoprotein | 4 | 0.833 | 0.500 | DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664) DUF641 (PF04859, IPR006943): Plant protein of unknown function (DUF641) DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972) SlyX (PF04102, IPR007236): SlyX XhlA (PF10779, IPR019715): Haemolysin XhlA TMF_TATA_bd (PF12325, IPR022091): TATA element modulatory factor 1 TATA binding Imm7 (PF15585, IPR028965): Immunity protein 7 CCCAP (PF15964, IPR031887): Centrosomal colon cancer autoantigen protein family DUF5082 (PF16888, IPR031681): Domain of unknown function (DUF5082) |
76 |
SF3A2 | interactor | 15 | 0.724 | 4.161 | Cytadhesin_P30 (PF07271, IPR009896): Cytadhesin P30/P32 PRP4 (PF08799, IPR014906): pre-mRNA processing factor 4 (PRP4) like Totivirus_coat (PF05518, IPR008871): Totivirus coat protein zf-met (PF12874): Zinc-finger of C2H2 type ARL6IP6 (PF15062, IPR029383): Haemopoietic lineage transmembrane helix SF3A2 (PF16835, IPR031781): Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) |
77 |
SF3B3 | interactor | 24 | 0.511 | 41.816 | CPSF_A (PF03178, IPR004871): CPSF A subunit region MMS1_N (PF10433): Mono-functional DNA-alkylating methyl methanesulfonate N-term |
78 |
SFN | suppressor | 10 | 0.444 | 7.712 | 14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein |
79 |
SIRT7 | interactor | 16 | 0.433 | 21.205 | DUF563 (PF04577, IPR007657): Protein of unknown function (DUF563) SIR2 (PF02146, IPR003000): Sir2 family |
80 |
SNW1 | protein found in more fusions | 28 | 0.450 | 81.703 | SKIP_SNW (PF02731, IPR004015): SKIP/SNW domain PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term SIR4_SID (PF16991, IPR031556): Sir4 SID domain |
81 |
SORT1 | interactor | 2 | 1.000 | 0 | Sortilin_C (PF15901, IPR031777): Sortilin, neurotensin receptor 3, C-terminal Sortilin-Vps10 (PF15902, IPR031778): Sortilin, neurotensin receptor 3 |
82 |
SREK1 | protein found in more fusions | 17 | 0.592 | 8.442 | Ureide_permease (PF07168, IPR009834): Ureide permease RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RP-C_C (PF11800, IPR021760): Replication protein C C-terminal region PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term DUF3915 (PF13054, IPR025026): Protein of unknown function (DUF3915) BRD4_CDT (PF17105, IPR031354): C-terminal domain of bromodomain protein 4 |
83 |
SRPK1 | interactor | 22 | 0.597 | 19.566 | FYDLN_acid (PF09538, IPR012644): Protein of unknown function (FYDLN_acid) Pkinase (PF00069, IPR000719): Protein kinase domain NARP1 (PF12569, IPR021183): NMDA receptor-regulated protein 1 |
84 |
SRPK2 | oncoprotein | 23 | 0.610 | 21.082 | DUF1387 (PF07139, IPR009816): Protein of unknown function (DUF1387) Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator Pkinase (PF00069, IPR000719): Protein kinase domain S-antigen (PF05756, IPR008825): S-antigen protein DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360) |
85 |
SRRM1 | interactor | 25 | 0.493 | 39.323 | DUF1754 (PF08555, IPR013865): Eukaryotic family of unknown function (DUF1754) ETRAMP (PF09716, IPR006389): Malarial early transcribed membrane protein (ETRAMP) Hepatitis_core (PF00906, IPR002006): Hepatitis core antigen MAP65_ASE1 (PF03999, IPR007145): Microtubule associated protein (MAP65/ASE1 family) PWI (PF01480, IPR002483, SM00311): PWI domain Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein |
86 |
SRSF1 | protein found in more fusions | 44 | 0.398 | 195.684 | Corona_nucleoca (PF00937, IPR001218): Coronavirus nucleocapsid protein RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 |
87 |
SRSF11 | interactor | 17 | 0.640 | 12.491 | Rtf2 (PF04641, IPR027799): Rtf2 RING-finger RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TP2 (PF01254, IPR000678): Nuclear transition protein 2 Transformer (PF06495, IPR010519): Fruit fly transformer protein FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 |
88 |
SRSF3 | oncoprotein | 34 | 0.403 | 127.422 | DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777) RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
89 |
SRSF4 | interactor | 20 | 0.495 | 34.251 | Corona_nucleoca (PF00937, IPR001218): Coronavirus nucleocapsid protein RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term |
90 |
SRSF9 | interactor | 22 | 0.571 | 22.478 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
91 |
STIP1 | interactor | 7 | 0.714 | 2.500 | TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat TPR_9 (PF13371, IPR011990): Tetratricopeptide repeat TPR_11 (PF13414, IPR011990): TPR repeat TPR_12 (PF13424): Tetratricopeptide repeat TPR_17 (PF13431): Tetratricopeptide repeat Wtap (PF17098, IPR029732): Pre-mRNA-splicing regulator WTAP |
92 |
SUB1 | interactor | 10 | 0.444 | 8.490 | Dehydrin (PF00257, IPR000167): Dehydrin PC4 (PF02229, IPR003173): Transcriptional Coactivator p15 (PC4) |
93 |
TBC1D9 | interactor | 1 | 0 | 0 | GRAM (PF02893, IPR004182, SM00568): GRAM domain RabGAP-TBC (PF00566, IPR000195, SM00164): Rab-GTPase-TBC domain EF-hand_1 (PF00036, IPR002048, SM00054): EF hand |
94 |
TCF4 | suppressor | 4 | 0.833 | 0.143 | CDC45 (PF02724, IPR003874): CDC45-like protein HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain |
95 |
TCTN1 | interactor | 1 | 0 | 0 | DUF1619 (PF07773, IPR011677): Protein of unknown function (DUF1619) |
96 |
TCTN3 | interactor | 5 | 0.500 | 4.167 | DUF1619 (PF07773, IPR011677): Protein of unknown function (DUF1619) |
97 |
TMEM126A | interactor | 3 | 1.000 | 0 | TMEM126 (PF07114, IPR009801): Transmembrane protein 126 |
98 |
TPM4 | oncoprotein | 4 | 0.833 | 0.143 | Tropomyosin (PF00261, IPR000533): Tropomyosin Tropomyosin_1 (PF12718, IPR000533): Tropomyosin like |
99 |
TRA2B | interactor | 29 | 0.495 | 70.779 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Transformer (PF06495, IPR010519): Fruit fly transformer protein |
100 |
TRIM27 | oncoprotein | 8 | 0.333 | 7.990 | IncA (PF04156, IPR007285): IncA protein SPRY (PF00622, IPR003877, SM00449): SPRY domain zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger PRY (PF13765, IPR006574, SM00589): SPRY-associated domain zf-C2H2_4 (PF13894): C2H2-type zinc finger zf-RING_5 (PF14634, IPR001841): zinc-RING finger domain zf-C3HC4_4 (PF15227): zinc finger of C3HC4-type, RING Lebercilin (PF15619, IPR028933): Ciliary protein causing Leber congenital amaurosis disease |
101 |
TTN | interactor | 8 | 0.821 | 1.279 | DUF11 (PF01345, IPR001434): Domain of unknown function DUF11 fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region I-set (PF07679, IPR013098): Immunoglobulin I-set domain Pkinase (PF00069, IPR000719): Protein kinase domain PPAK (PF02818, IPR004168): PPAK motif Titin_Z (PF09042, IPR015129): Titin Z V-set (PF07686, IPR013106): Immunoglobulin V-set domain Y_Y_Y (PF07495, IPR011123): Y_Y_Y domain DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369) Ig_3 (PF13927): Immunoglobulin domain |
102 |
U2AF1 | oncoprotein | 20 | 0.616 | 19.344 | DUF1509 (PF07420, IPR010883): Protein of unknown function (DUF1509) KMP11 (PF03037, IPR004132): Kinetoplastid membrane protein 11 RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH (PF00642, IPR000571): Zinc finger C-x8-C-x5-C-x3-H type (and similar) |
103 |
U2AF2 | protein found in more fusions | 42 | 0.448 | 124.349 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Transformer (PF06495, IPR010519): Fruit fly transformer protein |
104 |
UBA2 | interactor | 8 | 0.500 | 10.533 | ThiF (PF00899, IPR000594): ThiF family UAE_UbL (PF14732, IPR028077): Ubiquitin/SUMO-activating enzyme ubiquitin-like domain UBA2_C (PF16195, IPR032426): SUMO-activating enzyme subunit 2 C-terminus |
105 |
UBE2B | interactor | 6 | 0.400 | 5.667 | UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme |
106 |
UBQLN4 | interactor | 8 | 0.333 | 13.167 | CRF (PF00473, IPR000187, SM00039): Corticotropin-releasing factor family DUF1180 (PF06679, IPR009565): Protein of unknown function (DUF1180) Arm_2 (PF04826, IPR006911): Armadillo-like NUDE_C (PF04880, IPR006964): NUDE protein, C-terminal conserved region UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain XPC-binding (PF09280, IPR015360): XPC-binding domain ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family Fur_reg_FbpB (PF13040, IPR025004): Fur-regulated basic protein B partial_CstF (PF15861, IPR031721): Partial cleavage stimulation factor domain |
107 |
XPO1 | interactor | 25 | 0.280 | 128.272 | CRM1_C (PF08767, IPR014877, SM01102): CRM1 C terminal Hydrolase_3 (PF08282, IPR023214): haloacid dehalogenase-like hydrolase IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain Xpo1 (PF08389, IPR013598): Exportin 1-like protein Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region |
108 |
YAP1 | suppressor | 8 | 0.464 | 9.806 | Bindin (PF02084, IPR000775): Bindin WW (PF00397, IPR001202, SM00456): WW domain GspL_C (PF12693, IPR025691): GspL periplasmic domain FAM181 (PF15238, IPR029359): FAM181 |
109 |
YWHAE | oncoprotein | 19 | 0.474 | 41.448 | 14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein |