1 |
SP1 | parental protein | 226 | 0.062 | 31799.432 | zf-Di19 (PF05605, IPR008598): Drought induced 19 protein (Di19), zinc-binding Herpes_capsid (PF06112, IPR009299): Gammaherpesvirus capsid protein zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type Miga (PF10265, IPR019392): Mitoguardin zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 |
2 |
AATF | oncoprotein | 10 | 0.489 | 5.754 | DARPP-32 (PF05395, IPR008466): Protein phosphatase inhibitor 1/DARPP-32 RR_TM4-6 (PF06459, IPR009460): Ryanodine Receptor TM 4-6 TRAUB (PF08164, IPR012617): Apoptosis-antagonizing transcription factor, C-terminal Vif (PF00559, IPR000475): Retroviral Vif (Viral infectivity) protein AATF-Che1 (PF13339, IPR025160): Apoptosis antagonizing transcription factor |
3 |
ACTBL2 | interactor | 6 | 0.667 | 1.819 | Actin (PF00022, IPR004000, SM00268): Actin |
4 |
ACTC1 | interactor | 6 | 0.533 | 3.752 | Actin (PF00022, IPR004000, SM00268): Actin |
5 |
ACTG1 | protein found in more fusions | 11 | 0.622 | 5.546 | Actin (PF00022, IPR004000, SM00268): Actin |
6 |
AHR | suppressor | 16 | 0.514 | 19.444 | HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain PAS (PF00989, IPR013767, SM00091): PAS fold PAS_3 (PF08447, IPR013655): PAS fold PAS_4 (PF08448, IPR013656): PAS fold |
7 |
ANXA2 | interactor | 11 | 0.618 | 9.307 | Annexin (PF00191, IPR018502, SM00335): Annexin |
8 |
AR | oncoprotein | 46 | 0.297 | 282.468 | Androgen_recep (PF02166, IPR001103): Androgen receptor zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor |
9 |
ARHGAP21 | interactor | 5 | 0.700 | 2.000 | PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) RhoGAP (PF00620, IPR000198, SM00324): RhoGAP domain MAJIN (PF15077, IPR027816): Membrane-anchored junction protein PH_9 (PF15410): Pleckstrin homology domain |
10 |
ARNT | oncoprotein | 9 | 0.639 | 2.390 | HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain PAS (PF00989, IPR013767, SM00091): PAS fold PAS_11 (PF14598): PAS domain PRAS (PF15798, IPR026682): Proline-rich AKT1 substrate 1 |
11 |
ATF6 | interactor | 8 | 0.476 | 4.490 | bZIP_1 (PF00170, IPR004827): bZIP transcription factor DUF2749 (PF10907, IPR024475): Protein of unknown function (DUF2749) |
12 |
ATF7IP | oncoprotein | 6 | 0.467 | 4.034 | TCP (PF03634, IPR005333): TCP family transcription factor DUF2951 (PF11166, IPR021337): Protein of unknown function (DUF2951) ALMT (PF11744, IPR020966): Aluminium activated malate transporter ATF7IP_BD (PF16788, IPR031870): ATF-interacting protein binding domain fn3_4 (PF16794, IPR003961): Fibronectin-III type domain |
13 |
ATF7IP2 | interactor | 2 | 1.000 | 0 | ATF7IP_BD (PF16788, IPR031870): ATF-interacting protein binding domain fn3_4 (PF16794, IPR003961): Fibronectin-III type domain |
14 |
BCL11B | oncoprotein | 8 | 0.607 | 3.675 | FYVE (PF01363, IPR000306, SM00064): FYVE zinc finger zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-CCHC_2 (PF13696, IPR025829): Zinc knuckle zf-H2C2_5 (PF13909): C2H2-type zinc-finger domain |
15 |
BCOR | oncoprotein | 9 | 0.786 | 1.024 | Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) BCOR (PF15808, IPR031628): BCL-6 co-repressor, non-ankyrin-repeat region PUFD (PF16553, IPR032365): BCORL-PCGF1-binding domain |
16 |
BRCA1 | suppressor | 64 | 0.224 | 809.884 | BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger) BRCT_assoc (PF12820, IPR025994): Serine-rich domain associated with BRCT |
17 |
BRCA2 | suppressor | 8 | 0.750 | 1.995 | BRCA-2_helical (PF09169, IPR015252): BRCA2, helical BRCA-2_OB1 (PF09103, IPR015187): BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 BRCA-2_OB3 (PF09104, IPR015188): BRCA2, oligonucleotide/oligosaccharide-binding, domain 3 BRCA2 (PF00634, IPR002093): BRCA2 repeat Tower (PF09121, IPR015205): Tower |
18 |
BTRC | oncoprotein | 29 | 0.262 | 129.996 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Beta-TrCP_D (PF12125, IPR021977, SM01028): D domain of beta-TrCP ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain F-box-like (PF12937, IPR001810): F-box-like |
19 |
CALM1 | interactor | 17 | 0.257 | 56.978 | EF-hand_7 (PF13499, IPR011992): EF-hand domain pair |
20 |
CAPZB | interactor | 12 | 0.439 | 23.762 | Cytochrom_B562 (PF07361, IPR009155): Cytochrome b562 F_actin_cap_B (PF01115, IPR001698): F-actin capping protein, beta subunit |
21 |
CASP3 | interactor | 15 | 0.319 | 32.679 | Peptidase_C14 (PF00656, IPR011600): Caspase domain |
22 |
CASP6 | interactor | 5 | 0.667 | 0.667 | Peptidase_C14 (PF00656, IPR011600): Caspase domain |
23 |
CASP7 | interactor | 6 | 0.700 | 0.792 | Peptidase_C14 (PF00656, IPR011600): Caspase domain PRIMA1 (PF16101): Proline-rich membrane anchor 1 |
24 |
CBX5 | suppressor | 20 | 0.240 | 80.390 | Chromo (PF00385, IPR023780, SM00298): Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow (PF01393, IPR008251, SM00300): Chromo shadow domain |
25 |
CCNA1 | interactor | 10 | 0.667 | 4.065 | Cyclin_C (PF02984, IPR004367): Cyclin, C-terminal domain Cyclin_N (PF00134, IPR006671): Cyclin, N-terminal domain Cyclin_N2 (PF16500, IPR032447): N-terminal region of cyclin_N |
26 |
CCNA2 | oncoprotein | 21 | 0.442 | 43.923 | Cyclin_C (PF02984, IPR004367): Cyclin, C-terminal domain Cyclin_N (PF00134, IPR006671): Cyclin, N-terminal domain Cyclin_N2 (PF16500, IPR032447): N-terminal region of cyclin_N |
27 |
CCNB1 | oncoprotein | 11 | 0.691 | 4.132 | Adeno_E1A (PF02703, IPR003853): Early E1A protein Cyclin_C (PF02984, IPR004367): Cyclin, C-terminal domain Cyclin_N (PF00134, IPR006671): Cyclin, N-terminal domain |
28 |
CCND1 | oncoprotein | 20 | 0.550 | 14.395 | Cyclin_C (PF02984, IPR004367): Cyclin, C-terminal domain Cyclin_N (PF00134, IPR006671): Cyclin, N-terminal domain |
29 |
CDC42BPB | interactor | 1 | 0 | 0 | CNH (PF00780, IPR001180, SM00036): CNH domain DMPK_coil (PF08826, IPR014930): DMPK coiled coil domain like PBD (PF00786, IPR000095, SM00285): P21-Rho-binding domain PH (PF00169, IPR001849, SM00233): PH domain Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein Uso1_p115_C (PF04871, IPR006955): Uso1 / p115 like vesicle tethering protein, C terminal region XkdW (PF09636, IPR019094): XkdW protein C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain) DUF3450 (PF11932, IPR016866): Protein of unknown function (DUF3450) KELK (PF15796, IPR031597): KELK-motif containing domain of MRCK Ser/Thr protein kinase |
30 |
CDK1 | oncoprotein | 21 | 0.458 | 39.833 | Pkinase (PF00069, IPR000719): Protein kinase domain |
31 |
CDK2 | suppressor | 67 | 0.170 | 1089.969 | Kdo (PF06293, IPR010440): Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase (PF00069, IPR000719): Protein kinase domain |
32 |
CDK4 | oncoprotein | 15 | 0.448 | 16.700 | Pkinase (PF00069, IPR000719): Protein kinase domain |
33 |
CDKN2A | suppressor | 27 | 0.333 | 105.131 | Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_5 (PF13857): Ankyrin repeats (many copies) |
34 |
CEBPB | oncoprotein | 26 | 0.560 | 29.465 | RhlB (PF12300, IPR022077): ATP-dependent RNA helicase RhlB FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 |
35 |
CNTLN | interactor | 3 | 1.000 | 0 | APG6 (PF04111, IPR007243): Autophagy protein Apg6 ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16) CALCOCO1 (PF07888, IPR012852): Calcium binding and coiled-coil domain (CALCOCO1) like DUF745 (PF05335, IPR007999): Protein of unknown function (DUF745) HrpB7 (PF09486, IPR013392): Bacterial type III secretion protein (HrpB7) Cnn_1N (PF07989, IPR012943): Centrosomin N-terminal motif 1 Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein Spc24 (PF08286, IPR013252): Spc24 subunit of Ndc80 TSC22 (PF01166, IPR000580): TSC-22/dip/bun family Uso1_p115_C (PF04871, IPR006955): Uso1 / p115 like vesicle tethering protein, C terminal region Cep57_CLD_2 (PF14197, IPR025925): Centrosome localisation domain of PPC89 PRKG1_interact (PF15898, IPR031775): cGMP-dependent protein kinase interacting domain |
36 |
COL3A1 | oncoprotein | 1 | 0 | 0 | COLFI (PF01410, IPR000885, SM00038): Fibrillar collagen C-terminal domain Collagen (PF01391, IPR008160): Collagen triple helix repeat (20 copies) DUF1860 (PF08949, IPR015044): Domain of unknown function (DUF1860) VWC (PF00093, IPR001007, SM00214): von Willebrand factor type C domain |
37 |
CREBBP | suppressor | 64 | 0.255 | 656.485 | Creb_binding (PF09030, IPR014744): Creb binding DUF902 (PF06001, IPR010303): Domain of Unknown Function (DUF902) Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region KIX (PF02172, IPR003101): KIX domain MAS20 (PF02064, IPR002056): MAS20 protein import receptor TPX2 (PF06886, IPR027329): Targeting protein for Xklp2 (TPX2) zf-TAZ (PF02135, IPR000197, SM00551): TAZ zinc finger ANAPC_CDC26 (PF10471, IPR018860): Anaphase-promoting complex APC subunit CDC26 HAT_KAT11 (PF08214, IPR013178): Histone acetylation protein Bromodomain (PF00439, IPR001487, SM00297): Bromodomain ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type DUF3729 (PF12526, IPR022202): Protein of unknown function (DUF3729) DUF4834 (PF16118, IPR032272): Domain of unknown function (DUF4834) |
38 |
CRX | interactor | 4 | 0.833 | 0.500 | TF_Otx (PF03529, IPR013851): Otx1 transcription factor Homeobox (PF00046, IPR001356, SM00389): Homeobox domain SUIM_assoc (PF16619): Unstructured region C-term to UIM in Ataxin3 |
39 |
CTBP1 | protein found in more fusions | 21 | 0.442 | 39.286 | 2-Hacid_dh_C (PF02826, IPR006140): D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Cellsynth_D (PF03500, IPR022798): Cellulose synthase subunit D |
40 |
CTCFL | suppressor | 3 | 0.667 | 0.111 | PHD (PF00628, IPR019787, SM00249): PHD-finger zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_4 (PF13894): C2H2-type zinc finger zf-H2C2_5 (PF13909): C2H2-type zinc-finger domain |
41 |
CTNNB1 | oncoprotein | 37 | 0.294 | 197.660 | Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat Atx10homo_assoc (PF09759, IPR019156): Spinocerebellar ataxia type 10 protein domain DUF3361 (PF11841, IPR024574): Domain of unknown function (DUF3361) HEAT_EZ (PF13513): HEAT-like repeat |
42 |
DBN1 | oncoprotein | 23 | 0.304 | 100.969 | Pinin_SDK_memA (PF04696, IPR006786): pinin/SDK/memA/ protein conserved region Cofilin_ADF (PF00241, IPR002108, SM00102): Cofilin/tropomyosin-type actin-binding protein CAF-1_p150 (PF11600): Chromatin assembly factor 1 complex p150 subunit, N-terminal MSA-2c (PF12238, IPR021060): Merozoite surface antigen 2c |
43 |
DCAF6 | interactor | 5 | 0.500 | 1.310 | Herpes_pp85 (PF04637, IPR006731): Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat DUF3408 (PF11888, IPR021823): Protein of unknown function (DUF3408) ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain ATAD4 (PF15321, IPR028237): ATPase family AAA domain containing 4 MRI (PF15325, IPR028278): Modulator of retrovirus infection WD40_like (PF17005, IPR031544): WD40-like domain |
44 |
DDX3X | suppressor | 13 | 0.410 | 23.955 | DEAD (PF00270, IPR011545): DEAD/DEAH box helicase DUF755 (PF05501, IPR008474): Domain of unknown function (DUF755) Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain |
45 |
DDX5 | oncoprotein | 21 | 0.532 | 19.401 | DEAD (PF00270, IPR011545): DEAD/DEAH box helicase P68HR (PF08061, IPR012587): P68HR (NUC004) repeat ResIII (PF04851, IPR006935): Type III restriction enzyme, res subunit Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain |
46 |
DES | interactor | 3 | 0.667 | 0.500 | Filament (PF00038, IPR001664): Intermediate filament protein Filament_head (PF04732, IPR006821): Intermediate filament head (DNA binding) region HAUS-augmin3 (PF14932, IPR032733): HAUS augmin-like complex subunit 3 |
47 |
DNMT1 | suppressor | 18 | 0.507 | 24.227 | BAH (PF01426, IPR001025, SM00439): BAH domain DMAP_binding (PF06464, IPR010506, SM01137): DMAP1-binding Domain DNA_methylase (PF00145, IPR001525): C-5 cytosine-specific DNA methylase zf-CXXC (PF02008, IPR002857): CXXC zinc finger domain DNMT1-RFD (PF12047, IPR022702): Cytosine specific DNA methyltransferase replication foci domain |
48 |
E2F1 | suppressor | 30 | 0.343 | 123.028 | Cellsynth_D (PF03500, IPR022798): Cellulose synthase subunit D E2F_TDP (PF02319, IPR003316): E2F/DP family winged-helix DNA-binding domain E2F_CC-MB (PF16421, IPR032198): E2F transcription factor CC-MB domain |
49 |
EGR1 | suppressor | 11 | 0.455 | 16.497 | zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type DUF3432 (PF11914, IPR021839): Domain of unknown function (DUF3432) DUF3446 (PF11928, IPR021849): Domain of unknown function (DUF3446) zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain |
50 |
ELF1 | interactor | 5 | 0.700 | 1.133 | Ets (PF00178, IPR000418, SM00413): Ets-domain PAPA-1 (PF04795, IPR006880): PAPA-1-like conserved region Elf-1_N (PF12310, IPR022084): Transcription factor protein N terminal |
51 |
EP300 | oncoprotein | 81 | 0.200 | 1295.329 | Creb_binding (PF09030, IPR014744): Creb binding DUF902 (PF06001, IPR010303): Domain of Unknown Function (DUF902) Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region KIX (PF02172, IPR003101): KIX domain RR_TM4-6 (PF06459, IPR009460): Ryanodine Receptor TM 4-6 TPX2 (PF06886, IPR027329): Targeting protein for Xklp2 (TPX2) zf-TAZ (PF02135, IPR000197, SM00551): TAZ zinc finger HAT_KAT11 (PF08214, IPR013178): Histone acetylation protein Bromodomain (PF00439, IPR001487, SM00297): Bromodomain ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type |
52 |
EPAS1 | suppressor | 19 | 0.438 | 26.264 | Corona_I (PF03187, IPR004876): Corona nucleocapsid I protein HIF-1a_CTAD (PF08778, IPR014887): HIF-1 alpha C terminal transactivation domain HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain PAS (PF00989, IPR013767, SM00091): PAS fold HIF-1 (PF11413, IPR021537): Hypoxia-inducible factor-1 PAS_11 (PF14598): PAS domain |
53 |
ESR1 | suppressor | 70 | 0.201 | 1038.736 | Oest_recep (PF02159, IPR001292): Oestrogen receptor zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor ESR1_C (PF12743, IPR024736): Oestrogen-type nuclear receptor final C-terminal |
54 |
ESR2 | suppressor | 10 | 0.667 | 2.661 | zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor ERbeta_N (PF12497, IPR021064): Estrogen receptor beta |
55 |
ESRRA | oncoprotein | 6 | 0.467 | 4.761 | zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor |
56 |
ESRRB | suppressor | 5 | 0.500 | 3.722 | zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor |
57 |
ESRRG | oncoprotein | 4 | 1.000 | 0 | zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor |
58 |
ETS1 | oncoprotein | 16 | 0.517 | 20.479 | Ets (PF00178, IPR000418, SM00413): Ets-domain SAM_PNT (PF02198, IPR003118, SM00251): Sterile alpha motif (SAM)/Pointed domain |
59 |
FEZF1 | interactor | 1 | 0 | 0 | zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain |
60 |
FGFR1OP2 | oncoprotein | 1 | 0 | 0 | Cauli_AT (PF03233, IPR004917): Aphid transmission protein DUF837 (PF05769, IPR008555): Protein of unknown function (DUF837) Snapin_Pallidin (PF14712, IPR028119): Snapin/Pallidin |
61 |
FHL1 | suppressor | 10 | 0.556 | 9.387 | LIM (PF00412, IPR001781, SM00132): LIM domain zf-FCS (PF06467, IPR010507): MYM-type Zinc finger with FCS sequence motif |
62 |
FKBP15 | interactor | 1 | 0 | 0 | Filament (PF00038, IPR001664): Intermediate filament protein FKBP_C (PF00254, IPR001179): FKBP-type peptidyl-prolyl cis-trans isomerase NPV_P10 (PF05531, IPR008702): Nucleopolyhedrovirus P10 protein SMN (PF06003, IPR010304): Survival motor neuron protein (SMN) Spc24 (PF08286, IPR013252): Spc24 subunit of Ndc80 WH1 (PF00568, IPR000697, SM00461): WH1 domain SOSSC (PF15925, IPR031821): SOSS complex subunit C TolA_bind_tri (PF16331, IPR032519): TolA binding protein trimerisation |
63 |
FOXM1 | oncoprotein | 9 | 0.611 | 2.949 | EspF (PF04806, IPR006891): EspF protein repeat Forkhead (PF00250, IPR001766, SM00339): Forkhead domain |
64 |
GABPA | interactor | 6 | 0.867 | 0.571 | Ets (PF00178, IPR000418, SM00413): Ets-domain SAM_PNT (PF02198, IPR003118, SM00251): Sterile alpha motif (SAM)/Pointed domain GABP-alpha (PF11620, IPR024668): GA-binding protein alpha chain Wap1 (PF16997, IPR031550): Wap1 domain |
65 |
GAK | oncoprotein | 6 | 0.667 | 1.590 | DnaJ (PF00226, IPR001623, SM00271): DnaJ domain DSPc (PF00782, IPR020422, SM00195): Dual specificity phosphatase, catalytic domain Pkinase (PF00069, IPR000719): Protein kinase domain PTEN_C2 (PF10409, IPR014020): C2 domain of PTEN tumour-suppressor protein |
66 |
GATA1 | oncoprotein | 13 | 0.423 | 16.618 | GATA (PF00320, IPR000679, SM00401): GATA zinc finger Vps36-NZF-N (PF16988, IPR031558): Vacuolar protein sorting 36 NZF-N zinc-finger domain |
67 |
GATA3 | oncoprotein | 9 | 0.333 | 10.820 | GATA (PF00320, IPR000679, SM00401): GATA zinc finger Vps36-NZF-N (PF16988, IPR031558): Vacuolar protein sorting 36 NZF-N zinc-finger domain |
68 |
GATA4 | suppressor | 6 | 0.400 | 3.065 | Apidaecin (PF00807, IPR004828): Apidaecin GATA-N (PF05349, IPR008013): GATA-type transcription activator, N-terminal DUF2387 (PF09526, IPR012658): Probable metal-binding protein (DUF2387) GATA (PF00320, IPR000679, SM00401): GATA zinc finger |
69 |
GATA6 | oncoprotein | 2 | 1.000 | 0 | GATA-N (PF05349, IPR008013): GATA-type transcription activator, N-terminal OrfB_Zn_ribbon (PF07282, IPR010095): Putative transposase DNA-binding domain DUF2387 (PF09526, IPR012658): Probable metal-binding protein (DUF2387) GATA (PF00320, IPR000679, SM00401): GATA zinc finger |
70 |
GBP1 | suppressor | 1 | 0 | 0 | GBP (PF02263, IPR015894): Guanylate-binding protein, N-terminal domain GBP_C (PF02841, IPR003191): Guanylate-binding protein, C-terminal domain |
71 |
HBZ | interactor | 1 | 0 | 0 | Globin (PF00042, IPR000971): Globin |
72 |
HCFC1 | protein found in more fusions | 14 | 0.436 | 14.241 | fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain Kelch_1 (PF01344, IPR006652, SM00612): Kelch motif Kelch_3 (PF13415): Galactose oxidase, central domain Kelch_5 (PF13854): Kelch motif zf-tcix (PF14952, IPR029269): Putative treble-clef, zinc-finger, Zn-binding |
73 |
HDAC1 | suppressor | 73 | 0.227 | 907.513 | FSAP_sig_propep (PF03032, IPR004275): Frog skin active peptide family signal and propeptide Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain |
74 |
HDAC2 | suppressor | 47 | 0.282 | 290.702 | Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain NARP1 (PF12569, IPR021183): NMDA receptor-regulated protein 1 |
75 |
HDAC3 | suppressor | 48 | 0.254 | 355.856 | Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain |
76 |
HDAC4 | oncoprotein | 32 | 0.256 | 160.522 | Borrelia_P83 (PF05262, IPR007926): Borrelia P83/100 protein Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit HDAC4_Gln (PF12203, IPR024643): Glutamine rich N terminal domain of histone deacetylase 4 |
77 |
HIC1 | suppressor | 7 | 0.467 | 2.619 | BTB (PF00651, IPR013069, SM00225): BTB/POZ domain zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_4 (PF13894): C2H2-type zinc finger |
78 |
HIF1A | suppressor | 27 | 0.547 | 34.432 | Dicty_REP (PF05086, IPR007778): Dictyostelium (Slime Mold) REP protein HIF-1a_CTAD (PF08778, IPR014887): HIF-1 alpha C terminal transactivation domain HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain PAS (PF00989, IPR013767, SM00091): PAS fold PAS_3 (PF08447, IPR013655): PAS fold HIF-1 (PF11413, IPR021537): Hypoxia-inducible factor-1 |
79 |
HINT1 | suppressor | 6 | 0.600 | 0.817 | HIT (PF01230, IPR001310): HIT domain |
80 |
HLTF | suppressor | 4 | 0.667 | 0.143 | HIRAN (PF08797, IPR014905, SM00910): HIRAN domain SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger) |
81 |
HMGA1 | oncoprotein | 22 | 0.351 | 63.209 | AT_hook (PF02178, IPR017956, SM00384): AT hook motif DUF2239 (PF09998, IPR018715): Uncharacterized protein conserved in bacteria (DUF2239) |
82 |
HNF4A | suppressor | 18 | 0.463 | 25.388 | zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor |
83 |
HOXC11 | oncoprotein | 5 | 0.400 | 2.625 | DUF3528 (PF12045, IPR021918): Protein of unknown function (DUF3528) |
84 |
HSP90AA1 | oncoprotein | 40 | 0.254 | 265.693 | HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HSP90 (PF00183, IPR001404): Hsp90 protein |
85 |
HSPA9 | oncoprotein | 8 | 0.571 | 5.297 | HSP70 (PF00012, IPR013126): Hsp70 protein |
86 |
HTT | protein found in more fusions | 14 | 0.385 | 27.357 | HEAT (PF02985, IPR000357): HEAT repeat SPX (PF03105, IPR004331): SPX domain TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit DUF3652 (PF12372, IPR024613): Huntingtin protein region Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region HEAT_EZ (PF13513): HEAT-like repeat HEAT_2 (PF13646): HEAT repeats |
87 |
IFI16 | suppressor | 13 | 0.385 | 21.409 | HIN (PF02760, IPR004021): HIN-200/IF120x domain PYRIN (PF02758, IPR004020): PAAD/DAPIN/Pyrin domain Mitofilin (PF09731, IPR019133): Mitochondrial inner membrane protein |
88 |
IL1B | oncoprotein | 2 | 1.000 | 0 | IL1 (PF00340, IPR000975, SM00125): Interleukin-1 / 18 IL1_propep (PF02394, IPR003502): Interleukin-1 propeptide |
89 |
JUN | oncoprotein | 43 | 0.355 | 202.035 | bZIP_1 (PF00170, IPR004827): bZIP transcription factor Jun (PF03957, IPR005643): Jun-like transcription factor |
90 |
KIF1A | interactor | 5 | 0.500 | 0.566 | FHA (PF00498, IPR000253, SM00240): FHA domain IncA (PF04156, IPR007285): IncA protein PH (PF00169, IPR001849, SM00233): PH domain Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein Kinesin (PF00225, IPR001752, SM00129): Kinesin motor domain KIF1B (PF12423, IPR022140): Kinesin protein 1B Sox_N (PF12444, IPR022151): Sox developmental protein N terminal DUF3694 (PF12473, IPR022164): Kinesin protein Kinesin_assoc (PF16183, IPR032405): Kinesin-associated |
91 |
KLF10 | suppressor | 3 | 0.667 | 0.222 | zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain AAA_33 (PF13671): AAA domain |
92 |
KLF4 | suppressor | 12 | 0.561 | 11.646 | zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain |
93 |
KLF6 | suppressor | 4 | 0.500 | 0.689 | zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain |
94 |
KLF9 | interactor | 3 | 0.667 | 0.333 | zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain |
95 |
LDB1 | oncoprotein | 5 | 0.700 | 0.802 | LIM_bind (PF01803): LIM-domain binding protein |
96 |
LMO2 | oncoprotein | 12 | 0.327 | 24.881 | CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal LIM (PF00412, IPR001781, SM00132): LIM domain |
97 |
LMO7 | oncoprotein | 7 | 0.571 | 4.633 | CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain DUF1764 (PF08576, IPR013885): Eukaryotic protein of unknown function (DUF1764) LIM (PF00412, IPR001781, SM00132): LIM domain PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) DUF2072 (PF09845, IPR018645): Zn-ribbon containing protein AAA_23 (PF13476): AAA domain DUF4757 (PF15949, IPR031865): Domain of unknown function (DUF4757) |
98 |
LUZP1 | interactor | 5 | 0.700 | 1.400 | Trimer_CC (PF08954, IPR015049, SM01167): Trimerisation motif DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972) EMP24_GP25L (PF01105, IPR009038): emp24/gp25L/p24 family/GOLD Fzo_mitofusin (PF04799, IPR006884): fzo-like conserved region MerR-DNA-bind (PF09278, IPR015358): MerR, DNA binding Neur_chan_memb (PF02932, IPR006029): Neurotransmitter-gated ion-channel transmembrane region TMA7 (PF09072, IPR015157): Translation machinery associated TMA7 HD_assoc (PF13286, IPR026875): Phosphohydrolase-associated domain DUF4298 (PF14131, IPR025384): Domain of unknown function (DUF4298) PRKG1_interact (PF15898, IPR031775): cGMP-dependent protein kinase interacting domain |
99 |
MAPK1 | oncoprotein | 33 | 0.339 | 140.323 | Pkinase (PF00069, IPR000719): Protein kinase domain |
100 |
MAPK14 | oncoprotein | 17 | 0.400 | 36.412 | Pkinase (PF00069, IPR000719): Protein kinase domain |
101 |
MAPK3 | oncoprotein | 20 | 0.368 | 55.531 | Pkinase (PF00069, IPR000719): Protein kinase domain |
102 |
MAPK8 | oncoprotein | 15 | 0.549 | 10.211 | DUF530 (PF04409, IPR007503): Protein of unknown function (DUF530) Pkinase (PF00069, IPR000719): Protein kinase domain |
103 |
MBD1 | interactor | 7 | 0.286 | 10.675 | MBD (PF01429, IPR001739, SM00391): Methyl-CpG binding domain zf-CXXC (PF02008, IPR002857): CXXC zinc finger domain |
104 |
MECP2 | interactor | 10 | 0.422 | 10.386 | K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain MBD (PF01429, IPR001739, SM00391): Methyl-CpG binding domain SelP_N (PF04592, IPR007671): Selenoprotein P, N terminal region IHABP4_N (PF16174, IPR032381): Intracellular hyaluronan-binding protein 4 N-terminal |
105 |
MEF2C | oncoprotein | 9 | 0.361 | 9.972 | SRF-TF (PF00319, IPR002100, SM00432): SRF-type transcription factor (DNA-binding and dimerisation domain) HJURP_C (PF12347, IPR022102): Holliday junction regulator protein family C-terminal repeat |
106 |
MEF2D | oncoprotein | 10 | 0.511 | 6.186 | DUF2076 (PF09849, IPR018648): Uncharacterized protein conserved in bacteria (DUF2076) DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360) SRF-TF (PF00319, IPR002100, SM00432): SRF-type transcription factor (DNA-binding and dimerisation domain) HJURP_C (PF12347, IPR022102): Holliday junction regulator protein family C-terminal repeat |
107 |
MEIS2 | protein found in more fusions | 2 | 0 | 0 | Homeobox_KN (PF05920, IPR008422): Homeobox KN domain Meis_PKNOX_N (PF16493, IPR032453): N-terminal of Homeobox Meis and PKNOX1 |
108 |
MNAT1 | oncoprotein | 8 | 0.643 | 4.651 | MAT1 (PF06391, IPR015877): CDK-activating kinase assembly factor MAT1 Mu-like_Com (PF10122, IPR019294): Mu-like prophage protein Com zf-C3HC4_5 (PF17121, IPR001841): Zinc finger, C3HC4 type (RING finger) |
109 |
MSX1 | protein found in more fusions | 4 | 1.000 | 0 | Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein Homeobox (PF00046, IPR001356, SM00389): Homeobox domain |
110 |
MYC | oncoprotein | 49 | 0.307 | 324.536 | HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain Myc-LZ (PF02344, IPR003327): Myc leucine zipper domain Myc_N (PF01056, IPR012682): Myc amino-terminal region |
111 |
MYCN | oncoprotein | 4 | 0.833 | 0.133 | HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain Myc_N (PF01056, IPR012682): Myc amino-terminal region |
112 |
MYH10 | interactor | 5 | 0.700 | 1.567 | IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif Myosin_N (PF02736, IPR004009): Myosin N-terminal SH3-like domain Myosin_tail_1 (PF01576, IPR002928): Myosin tail Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain) |
113 |
MYH11 | oncoprotein | 4 | 0.500 | 1.567 | IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif Myosin_N (PF02736, IPR004009): Myosin N-terminal SH3-like domain Myosin_tail_1 (PF01576, IPR002928): Myosin tail Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain) CC2-LZ (PF16516, IPR032419): Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator |
114 |
MYH14 | interactor | 6 | 0.600 | 2.987 | IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif Myosin_N (PF02736, IPR004009): Myosin N-terminal SH3-like domain Myosin_tail_1 (PF01576, IPR002928): Myosin tail Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain) |
115 |
MYH7B | interactor | 4 | 1.000 | 0 | Myosin_N (PF02736, IPR004009): Myosin N-terminal SH3-like domain Myosin_tail_1 (PF01576, IPR002928): Myosin tail YkuI_C (PF10388, IPR018842): EAL-domain associated signalling protein domain Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain) |
116 |
MYH9 | suppressor | 31 | 0.234 | 230.830 | IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif Myosin_N (PF02736, IPR004009): Myosin N-terminal SH3-like domain Myosin_tail_1 (PF01576, IPR002928): Myosin tail Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain) |
117 |
MYL12A | interactor | 7 | 0.524 | 5.406 | EF-hand_11 (PF08976, IPR015070): EF-hand domain DUF2267 (PF10025, IPR018727): Uncharacterized conserved protein (DUF2267) EF-hand_7 (PF13499, IPR011992): EF-hand domain pair |
118 |
MYL3 | interactor | 1 | 0 | 0 | EF-hand_6 (PF13405, IPR002048): EF-hand domain EF-hand_7 (PF13499, IPR011992): EF-hand domain pair EF-hand_8 (PF13833, IPR002048): EF-hand domain pair |
119 |
MYL6B | interactor | 3 | 1.000 | 0 | SapB_1 (PF05184, IPR007856): Saposin-like type B, region 1 EF-hand_6 (PF13405, IPR002048): EF-hand domain EF-hand_7 (PF13499, IPR011992): EF-hand domain pair |
120 |
MYL9 | interactor | 5 | 0.800 | 0.733 | UPF0154 (PF03672, IPR005359): Uncharacterised protein family (UPF0154) EF-hand_6 (PF13405, IPR002048): EF-hand domain EF-hand_7 (PF13499, IPR011992): EF-hand domain pair |
121 |
MYO1B | interactor | 7 | 0.857 | 0.672 | IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif Myosin_TH1 (PF06017, IPR010926): Unconventional myosin tail, actin- and lipid-binding RNA_pol (PF00940, IPR002092): DNA-dependent RNA polymerase Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain) AAA_23 (PF13476): AAA domain |
122 |
MYO1C | interactor | 13 | 0.513 | 18.433 | IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif Myosin_TH1 (PF06017, IPR010926): Unconventional myosin tail, actin- and lipid-binding Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain) |
123 |
MYO1E | interactor | 5 | 0.500 | 2.619 | IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif Myosin_TH1 (PF06017, IPR010926): Unconventional myosin tail, actin- and lipid-binding Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain) SH3_1 (PF00018, IPR001452, SM00326): SH3 domain |
124 |
MYO6 | protein found in more fusions | 9 | 0.643 | 3.117 | BUD22 (PF09073, IPR015158): BUD22 IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif Myosin_N (PF02736, IPR004009): Myosin N-terminal SH3-like domain Rad9 (PF04139, IPR007268): Rad9 Sec62 (PF03839, IPR004728): Translocation protein Sec62 XhlA (PF10779, IPR019715): Haemolysin XhlA Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain) DUF4887 (PF16228, IPR032615): Domain of unknown function (DUF4887) Myosin-VI_CBD (PF16521, IPR032412): Myosin VI cargo binding domain |
125 |
MYOD1 | oncoprotein | 18 | 0.500 | 21.086 | Basic (PF01586, IPR002546, SM00520): Myogenic Basic domain HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain Mfp-3 (PF04202, IPR007328): Foot protein 3 Myf5 (PF12232, IPR022032): Myogenic determination factor 5 |
126 |
MYOG | interactor | 5 | 0.500 | 2.150 | Basic (PF01586, IPR002546, SM00520): Myogenic Basic domain HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain |
127 |
NAP1L1 | protein found in more fusions | 9 | 0.536 | 3.850 | NAP (PF00956, IPR002164): Nucleosome assembly protein (NAP) RNA_pol_3_Rpc31 (PF11705, IPR024661): DNA-directed RNA polymerase III subunit Rpc31 PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term |
128 |
NCL | protein found in more fusions | 18 | 0.382 | 39.689 | DUF1754 (PF08555, IPR013865): Eukaryotic family of unknown function (DUF1754) Myc_N (PF01056, IPR012682): Myc amino-terminal region RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) YL1 (PF05764, IPR008895): YL1 nuclear protein Limkain-b1 (PF11608, IPR024582): Limkain b1 |
129 |
NCOR1 | oncoprotein | 30 | 0.411 | 75.727 | BES1_N (PF05687, IPR008540): BES1/BZR1 plant transcription factor, N-terminal Lamp (PF01299, IPR002000): Lysosome-associated membrane glycoprotein (Lamp) MAS20 (PF02064, IPR002056): MAS20 protein import receptor Neur_chan_memb (PF02932, IPR006029): Neurotransmitter-gated ion-channel transmembrane region Eapp_C (PF10238, IPR019370): E2F-associated phosphoprotein Hid1 (PF12722): High-temperature-induced dauer-formation protein Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain DUF3915 (PF13054, IPR025026): Protein of unknown function (DUF3915) GPS2_interact (PF15784, IPR031557): G-protein pathway suppressor 2-interacting domain DUF4834 (PF16118, IPR032272): Domain of unknown function (DUF4834) RBR (PF17208): RNA binding Region |
130 |
NCOR2 | oncoprotein | 33 | 0.411 | 94.934 | CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal MAS20 (PF02064, IPR002056): MAS20 protein import receptor OAD_gamma (PF04277, IPR005899): Oxaloacetate decarboxylase, gamma chain PSK (PF06404, IPR009438): Phytosulfokine precursor protein (PSK) SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360) Gti1_Pac2 (PF09729, IPR018608): Gti1/Pac2 family PRCC (PF10253, IPR018800): Mitotic checkpoint regulator, MAD2B-interacting Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain Spt20 (PF12090, IPR021950): Spt20 family DUF3915 (PF13054, IPR025026): Protein of unknown function (DUF3915) DUF4518 (PF15008, IPR026698): Domain of unknown function (DUF4518) GPS2_interact (PF15784, IPR031557): G-protein pathway suppressor 2-interacting domain DUF4820 (PF16091, IPR032150): Domain of unknown function (DUF4820) |
131 |
NEB | oncoprotein | 7 | 0.381 | 9.167 | Peptidase_M24 (PF00557, IPR001714): Metallopeptidase family M24 Nebulin (PF00880, IPR000900, SM00227): Nebulin repeat Shal-type (PF11601, IPR021645): Shal-type voltage-gated potassium channels, N-terminal DUF3410 (PF11890, IPR024531): Domain of unknown function (DUF3410) DUF3417 (PF11897, IPR024517): Protein of unknown function (DUF3417) G-patch_2 (PF12656, IPR026822): DExH-box splicing factor binding site NFRKB_winged (PF14465, IPR025220): NFRKB Winged Helix-like SH3_9 (PF14604, IPR001452): Variant SH3 domain |
132 |
NEPRO | interactor | 2 | 1.000 | 0 | DUF4477 (PF14780, IPR027951): Domain of unknown function (DUF4477) |
133 |
NF2 | suppressor | 12 | 0.291 | 19.122 | ERM (PF00769, IPR011259): Ezrin/radixin/moesin family FERM_C (PF09380, IPR018980): FERM C-terminal PH-like domain FERM_M (PF00373, IPR019748): FERM central domain FERM_N (PF09379, IPR018979): FERM N-terminal domain |
134 |
NFKB1 | suppressor | 29 | 0.378 | 97.300 | Death (PF00531, IPR000488, SM00005): Death domain GHMP_kinases_C (PF08544, IPR013750): GHMP kinases C terminal RHD_DNA_bind (PF00554, IPR011539): Rel homology DNA-binding domain Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_4 (PF13637): Ankyrin repeats (many copies) RHD_dimer (PF16179, IPR032397): Rel homology dimerisation domain |
135 |
NFKB2 | oncoprotein | 9 | 0.607 | 4.875 | Ank (PF00023, IPR002110, SM00248): Ankyrin repeat Death (PF00531, IPR000488, SM00005): Death domain RHD_DNA_bind (PF00554, IPR011539): Rel homology DNA-binding domain Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_4 (PF13637): Ankyrin repeats (many copies) RHD_dimer (PF16179, IPR032397): Rel homology dimerisation domain |
136 |
NFYA | interactor | 18 | 0.379 | 48.992 | CBFB_NFYA (PF02045, IPR001289): CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B MSP1_C (PF07462, IPR010901): Merozoite surface protein 1 (MSP1) C-terminus FixG_C (PF11614, IPR032879): IG-like fold at C-terminal of FixG, putative oxidoreductase DUF4237 (PF14021, IPR025331): Protein of unknown function (DUF4237) |
137 |
NFYB | interactor | 11 | 0.782 | 2.595 | CBFD_NFYB_HMF (PF00808, IPR003958): Histone-like transcription factor (CBF/NF-Y) and archaeal histone |
138 |
NFYC | interactor | 12 | 0.515 | 15.268 | CBFD_NFYB_HMF (PF00808, IPR003958): Histone-like transcription factor (CBF/NF-Y) and archaeal histone E1-E2_ATPase (PF00122, IPR008250): E1-E2 ATPase Fucose_iso_C (PF02952, IPR015888): L-fucose isomerase, C-terminal domain |
139 |
NKX3-1 | suppressor | 6 | 0.467 | 4.434 | Trypan_PARP (PF05887, IPR008882): Procyclic acidic repetitive protein (PARP) Homeobox (PF00046, IPR001356, SM00389): Homeobox domain |
140 |
NPM1 | suppressor | 35 | 0.303 | 203.686 | Nucleoplasmin (PF03066): Nucleoplasmin SDA1 (PF05285, IPR007949): SDA1 NPM1-C (PF16276, IPR032569): Nucleophosmin C-terminal domain |
141 |
NR2E1 | interactor | 5 | 0.500 | 2.134 | zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor |
142 |
NR2F1 | oncoprotein | 6 | 0.467 | 3.905 | zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor |
143 |
NR5A1 | interactor | 5 | 0.600 | 1.605 | zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor PRIMA1 (PF16101): Proline-rich membrane anchor 1 |
144 |
NUP62 | interactor | 9 | 0.429 | 8.406 | Nsp1_C (PF05064, IPR007758): Nsp1-like C-terminal region GAS (PF13851, IPR025593): Growth-arrest specific micro-tubule binding Nucleoporin_FG2 (PF15967): Nucleoporin FG repeated region |
145 |
NXF1 | interactor | 39 | 0.132 | 400.405 | NTF2 (PF02136, IPR002075): Nuclear transport factor 2 (NTF2) domain Tap-RNA_bind (PF09162, IPR015245): Tap, RNA-binding TAP_C (PF03943, IPR005637, SM00804): TAP C-terminal domain LRR_8 (PF13855, IPR001611): Leucine rich repeat |
146 |
ODF2 | interactor | 6 | 0.333 | 6.186 | ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16) NAT (PF04768, IPR006855): NAT, N-acetyltransferase, of N-acetylglutamate synthase Invasin_D3 (PF09134, IPR015217): Invasin, domain 3 Mt_ATP-synt_D (PF05873, IPR008689): ATP synthase D chain, mitochondrial (ATP5H) CENP-F_leu_zip (PF10473, IPR019513): Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TMF_TATA_bd (PF12325, IPR022091): TATA element modulatory factor 1 TATA binding TMF_DNA_bd (PF12329, IPR022092): TATA element modulatory factor 1 DNA binding HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1 |
147 |
PARP1 | suppressor | 31 | 0.414 | 92.449 | BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain PADR1 (PF08063, IPR012982): PADR1 (NUC008) domain PARP (PF00644, IPR012317): Poly(ADP-ribose) polymerase catalytic domain PARP_reg (PF02877, IPR004102): Poly(ADP-ribose) polymerase, regulatory domain WGR (PF05406, IPR008893, SM00773): WGR domain zf-PARP (PF00645, IPR001510): Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region |
148 |
PFDN5 | interactor | 7 | 0.524 | 3.028 | Prefoldin (PF02996, IPR004127): Prefoldin subunit UPF0693 (PF16088, IPR032143): UPF0693 family |
149 |
PGR | suppressor | 17 | 0.467 | 30.392 | Prog_receptor (PF02161, IPR000128): Progesterone receptor zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor |
150 |
PHOX2A | suppressor | 4 | 1.000 | 0 | Phage_Mu_Gam (PF07352, IPR009951): Bacteriophage Mu Gam like protein Homeobox (PF00046, IPR001356, SM00389): Homeobox domain PRIMA1 (PF16101): Proline-rich membrane anchor 1 |
151 |
PIN1 | suppressor | 25 | 0.387 | 85.731 | Rotamase (PF00639, IPR000297): PPIC-type PPIASE domain WW (PF00397, IPR001202, SM00456): WW domain |
152 |
PLEC | oncoprotein | 6 | 0.600 | 2.369 | CDC37_N (PF03234, IPR013855, SM01071): Cdc37 N terminal kinase binding CENP-H (PF05837, IPR008426): Centromere protein H (CENP-H) CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972) Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family FUSC (PF04632, IPR006726): Fusaric acid resistance protein family RNA_pol_Rbc25 (PF08292, IPR013238): RNA polymerase III subunit Rpc25 S10_plectin (PF03501, IPR005326): Plectin/S10 domain Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein DUF2229 (PF09989, IPR018709): CoA enzyme activase uncharacterised domain (DUF2229) Plectin (PF00681, IPR001101, SM00250): Plectin repeat YlqD (PF11068, IPR021297): YlqD protein Alanine_zipper (PF11839, IPR021793): Alanine-zipper, major outer membrane lipoprotein DUF3391 (PF11871, IPR021812): Domain of unknown function (DUF3391) DUF4140 (PF13600, IPR025554): N-terminal domain of unknown function (DUF4140) |
153 |
PML | suppressor | 38 | 0.351 | 159.963 | zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger DUF3583 (PF12126, IPR021978): Protein of unknown function (DUF3583) zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger) |
154 |
POGZ | interactor | 6 | 0.467 | 4.400 | DDE_1 (PF03184, IPR004875): DDE superfamily endonuclease Rubredoxin (PF00301, IPR024935): Rubredoxin HTH_Tnp_Tc5 (PF03221, IPR006600, SM00674): Tc5 transposase DNA-binding domain zf-RRN7 (PF11781, IPR021752): Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain HTH_28 (PF13518): Helix-turn-helix domain zinc_ribbon_4 (PF13717): zinc-ribbon domain zf-C2H2_4 (PF13894): C2H2-type zinc finger zf-C2H2_6 (PF13912, IPR007087): C2H2-type zinc finger zf-RING_5 (PF14634, IPR001841): zinc-RING finger domain |
155 |
POTEE | interactor | 2 | 1.000 | 0 | Actin (PF00022, IPR004000, SM00268): Actin DUF3641 (PF12345, IPR024521): Protein of unknown function (DUF3641) Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) CCDC144C (PF14915): CCDC144C protein coiled-coil region |
156 |
POU2F1 | protein found in more fusions | 19 | 0.405 | 42.966 | Pou (PF00157, IPR000327, SM00352): Pou domain - N-terminal to homeobox domain Homeobox (PF00046, IPR001356, SM00389): Homeobox domain DUF3597 (PF12200, IPR022016): Domain of unknown function (DUF3597) |
157 |
PPARG | suppressor | 28 | 0.473 | 57.082 | zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor PPARgamma_N (PF12577, IPR022590): PPAR gamma N-terminal region |
158 |
PPIG | interactor | 1 | 0 | 0 | Ly49 (PF08391, IPR013600): Ly49-like protein, N-terminal region Pro_isomerase (PF00160, IPR002130): Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Med19 (PF10278, IPR019403): Mediator of RNA pol II transcription subunit 19 SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein Apis_Csd (PF11671, IPR021007): Complementary sex determiner protein PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term |
159 |
PPP1R13L | oncoprotein | 5 | 1.000 | 0 | Pex14_N (PF04695, IPR006785): Peroxisomal membrane anchor protein (Pex14p) conserved region DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360) Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) SH3_9 (PF14604, IPR001452): Variant SH3 domain PRIMA1 (PF16101): Proline-rich membrane anchor 1 |
160 |
PRKCD | suppressor | 10 | 0.611 | 5.764 | Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain) |
161 |
PRKCZ | interactor | 8 | 0.762 | 0.796 | PB1 (PF00564, IPR000270, SM00666): PB1 domain Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain) |
162 |
PRKDC | protein found in more fusions | 22 | 0.505 | 30.290 | FAT (PF02259, IPR003151): FAT domain FATC (PF02260, IPR003152): FATC domain NUC194 (PF08163, IPR012582): NUC194 domain PI3_PI4_kinase (PF00454, IPR000403, SM00146): Phosphatidylinositol 3- and 4-kinase |
163 |
PSIP1 | oncoprotein | 6 | 0.467 | 3.494 | AT_hook (PF02178, IPR017956, SM00384): AT hook motif BEX (PF04538, IPR021156): Brain expressed X-linked like family DUF1510 (PF07423, IPR009988): Protein of unknown function (DUF1510) PGA2 (PF07543, IPR011431): Protein trafficking PGA2 PWWP (PF00855, IPR000313, SM00293): PWWP domain LEDGF (PF11467, IPR021567): Lens epithelium-derived growth factor (LEDGF) TERB2 (PF15101, IPR028065): Telomere-associated protein TERB2 |
164 |
PSMC5 | protein found in more fusions | 15 | 0.407 | 29.701 | AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA) Laminin_II (PF06009, IPR010307): Laminin Domain II RILP (PF11461, IPR021563): Rab interacting lysosomal protein AAA_16 (PF13191): AAA ATPase domain |
165 |
PTPA | suppressor | 5 | 0.400 | 2.486 | PTPA (PF03095, IPR004327): Phosphotyrosyl phosphate activator (PTPA) protein |
166 |
PURA | interactor | 3 | 1.000 | 0 | PurA (PF04845, IPR006628, SM00712): PurA ssDNA and RNA-binding protein DUF3276 (PF11680, IPR021694): Protein of unknown function (DUF3276) FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 |
167 |
RAD51 | interactor | 12 | 0.400 | 16.314 | Rad51 (PF08423, IPR013632): Rad51 HHH_5 (PF14520): Helix-hairpin-helix domain |
168 |
RARA | oncoprotein | 22 | 0.448 | 31.265 | zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor |
169 |
RB1 | suppressor | 50 | 0.244 | 456.721 | RB_A (PF01858, IPR002720): Retinoblastoma-associated protein A domain RB_B (PF01857, IPR002719): Retinoblastoma-associated protein B domain Rb_C (PF08934, IPR015030): Rb C-terminal domain DUF3452 (PF11934, IPR024599): Domain of unknown function (DUF3452) DUF4592 (PF15262, IPR028030): Domain of unknown function (DUF4592) |
170 |
RBBP4 | oncoprotein | 25 | 0.427 | 68.025 | eIF2A (PF08662, IPR013979): Eukaryotic translation initiation factor eIF2A WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Capsid_NCLDV (PF04451, IPR007542): Large eukaryotic DNA virus major capsid protein CAF1C_H4-bd (PF12265, IPR022052): Histone-binding protein RBBP4 or subunit C of CAF1 complex |
171 |
RBBP7 | suppressor | 16 | 0.575 | 16.663 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Capsid_NCLDV (PF04451, IPR007542): Large eukaryotic DNA virus major capsid protein CAF1C_H4-bd (PF12265, IPR022052): Histone-binding protein RBBP4 or subunit C of CAF1 complex |
172 |
RBL1 | suppressor | 17 | 0.471 | 19.753 | RB_A (PF01858, IPR002720): Retinoblastoma-associated protein A domain RB_B (PF01857, IPR002719): Retinoblastoma-associated protein B domain Rb_C (PF08934, IPR015030): Rb C-terminal domain DUF3452 (PF11934, IPR024599): Domain of unknown function (DUF3452) |
173 |
REL | oncoprotein | 14 | 0.429 | 22.489 | RHD_DNA_bind (PF00554, IPR011539): Rel homology DNA-binding domain RHD_dimer (PF16179, IPR032397): Rel homology dimerisation domain |
174 |
RELA | oncoprotein | 51 | 0.293 | 371.803 | DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region RHD_DNA_bind (PF00554, IPR011539): Rel homology DNA-binding domain RHD_dimer (PF16179, IPR032397): Rel homology dimerisation domain |
175 |
REST | oncoprotein | 13 | 0.397 | 15.288 | CENP-H (PF05837, IPR008426): Centromere protein H (CENP-H) Presenilin (PF01080, IPR001108): Presenilin RNA_POL_M_15KD (PF02150, IPR001529): RNA polymerases M/15 Kd subunit zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type DNA_RNApol_7kD (PF03604, IPR006591, SM00659): DNA directed RNA polymerase, 7 kDa subunit zf-C2H2_jaz (PF12171, IPR022755): Zinc-finger double-stranded RNA-binding zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_4 (PF13894): C2H2-type zinc finger zf-H2C2_5 (PF13909): C2H2-type zinc-finger domain SLBP_RNA_bind (PF15247, IPR029344): Histone RNA hairpin-binding protein RNA-binding domain |
176 |
RNF4 | interactor | 9 | 0.429 | 5.229 | Sgf11 (PF08209, IPR013246): Sgf11 (transcriptional regulation protein) zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain zf-UDP (PF14569, IPR027934): Zinc-binding RING-finger |
177 |
RSF1 | oncoprotein | 2 | 1.000 | 0 | DDT (PF02791, IPR004022, SM00571): DDT domain DTHCT (PF08070, IPR012542): DTHCT (NUC029) region DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777) PHD (PF00628, IPR019787, SM00249): PHD-finger UPF0239 (PF06783, IPR009621): Uncharacterised protein family (UPF0239) TFIIE-A_C (PF11521, IPR021600): C-terminal general transcription factor TFIIE alpha Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal WHIM1 (PF15612, IPR028942): WSTF, HB1, Itc1p, MBD9 motif 1 |
178 |
RXRA | oncoprotein | 23 | 0.437 | 39.072 | zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor Nuc_recep-AF1 (PF11825, IPR021780): Nuclear/hormone receptor activator site AF-1 |
179 |
SENP3 | interactor | 13 | 0.487 | 17.831 | Nop53 (PF07767, IPR011687): Nop53 (60S ribosomal biogenesis) Peptidase_C48 (PF02902, IPR003653): Ulp1 protease family, C-terminal catalytic domain |
180 |
SENP6 | interactor | 1 | 0 | 0 | Peptidase_C48 (PF02902, IPR003653): Ulp1 protease family, C-terminal catalytic domain |
181 |
SFPQ | oncoprotein | 14 | 0.436 | 15.223 | GRP (PF07172, IPR010800): Glycine rich protein family Herpes_PAP (PF03325, IPR004997): Herpesvirus polymerase accessory protein NOPS (PF08075, IPR012975): NOPS (NUC059) domain RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit PAT1 (PF09770, IPR019167): Topoisomerase II-associated protein PAT1 CYSTM (PF12734, IPR028144): Cysteine-rich TM module stress tolerance |
182 |
SIN3A | oncoprotein | 32 | 0.319 | 162.259 | Sin3_corepress (PF08295, IPR013194, SM00761): Sin3 family co-repressor PAH (PF02671, IPR003822, SM00309): Paired amphipathic helix repeat Sin3a_C (PF16879, IPR031693): C-terminal domain of Sin3a protein |
183 |
SKP2 | suppressor | 23 | 0.399 | 57.338 | LRR_1 (PF00560, IPR001611): Leucine Rich Repeat LRR_2 (PF07723, IPR013101): Leucine Rich Repeat LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies) F-box-like (PF12937, IPR001810): F-box-like LRR_6 (PF13516, IPR001611): Leucine Rich repeat LRR_8 (PF13855, IPR001611): Leucine rich repeat |
184 |
SMAD2 | suppressor | 29 | 0.413 | 93.250 | MH1 (PF03165, IPR003619, SM00523): MH1 domain MH2 (PF03166, IPR001132, SM00524): MH2 domain |
185 |
SMAD3 | oncoprotein | 47 | 0.314 | 301.143 | MH1 (PF03165, IPR003619, SM00523): MH1 domain MH2 (PF03166, IPR001132, SM00524): MH2 domain |
186 |
SMAD4 | suppressor | 23 | 0.459 | 43.625 | MH1 (PF03165, IPR003619, SM00523): MH1 domain MH2 (PF03166, IPR001132, SM00524): MH2 domain |
187 |
SMARCA4 | suppressor | 40 | 0.369 | 173.102 | DUF1840 (PF08895, IPR014991): Domain of unknown function (DUF1840) HSA (PF07529, IPR014012, SM00573): HSA QLQ (PF08880, IPR014978, SM00951): QLQ SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain BRK (PF07533, IPR006576, SM00592): BRK domain Bromodomain (PF00439, IPR001487, SM00297): Bromodomain Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal DUF4065 (PF13274, IPR025272): Protein of unknown function (DUF4065) SnAC (PF14619, IPR029295): Snf2-ATP coupling, chromatin remodelling complex WRNPLPNID (PF15017): Putative WW-binding domain and destruction box |
188 |
SMARCC1 | suppressor | 18 | 0.618 | 11.203 | SWIRM (PF04433, IPR007526): SWIRM domain Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain DUF2618 (PF10940, IPR021237): Protein of unknown function (DUF2618) PTPRCAP (PF15713, IPR016553): Protein tyrosine phosphatase receptor type C-associated SWIRM-assoc_1 (PF16495, IPR032451): SWIRM-associated region 1 SWIRM-assoc_2 (PF16496, IPR032450): SWIRM-associated domain at the N-terminal SWIRM-assoc_3 (PF16498, IPR032448): SWIRM-associated domain at the C-terminal |
189 |
SMARCC2 | interactor | 17 | 0.507 | 21.841 | GHMP_kinases_N (PF00288, IPR006204): GHMP kinases N terminal domain SWIRM (PF04433, IPR007526): SWIRM domain DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360) Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain SWIRM-assoc_1 (PF16495, IPR032451): SWIRM-associated region 1 SWIRM-assoc_2 (PF16496, IPR032450): SWIRM-associated domain at the N-terminal SWIRM-assoc_3 (PF16498, IPR032448): SWIRM-associated domain at the C-terminal |
190 |
SP3 | interactor | 23 | 0.344 | 97.163 | K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain |
191 |
SP4 | interactor | 6 | 0.533 | 3.748 | zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360) Macoilin (PF09726, IPR019130): Transmembrane protein PAT1 (PF09770, IPR019167): Topoisomerase II-associated protein PAT1 DUF3446 (PF11928, IPR021849): Domain of unknown function (DUF3446) zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_4 (PF13894): C2H2-type zinc finger SEEEED (PF14797, IPR029394): Serine-rich region of AP3B1, clathrin-adaptor complex |
192 |
SREBF1 | interactor | 12 | 0.564 | 7.470 | HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain GIT_CC (PF16559, IPR032352): GIT coiled-coil Rho guanine nucleotide exchange factor |
193 |
SREBF2 | protein found in more fusions | 16 | 0.400 | 34.163 | HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit |
194 |
SRF | interactor | 21 | 0.347 | 66.617 | SRF-TF (PF00319, IPR002100, SM00432): SRF-type transcription factor (DNA-binding and dimerisation domain) |
195 |
SRRT | interactor | 5 | 0.400 | 2.202 | ARS2 (PF04959, IPR007042): Arsenite-resistance protein 2 DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777) RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TRAP_alpha (PF03896, IPR005595): Translocon-associated protein (TRAP), alpha subunit Macoilin (PF09726, IPR019130): Transmembrane protein DUF3546 (PF12066, IPR021933): Domain of unknown function (DUF3546) DUF4187 (PF13821, IPR025239): Domain of unknown function (DUF4187) |
196 |
SRY | interactor | 5 | 0.900 | 0.100 | DUF1908 (PF08926, IPR015022): Domain of unknown function (DUF1908) HMG_box (PF00505, IPR009071, SM00398): HMG (high mobility group) box |
197 |
STAT3 | suppressor | 33 | 0.345 | 152.973 | SH2 (PF00017, IPR000980, SM00252): SH2 domain STAT_alpha (PF01017, IPR013800): STAT protein, all-alpha domain STAT_bind (PF02864, IPR013801): STAT protein, DNA binding domain STAT_int (PF02865, IPR013799, SM00964): STAT protein, protein interaction domain |
198 |
STRAP | protein found in more fusions | 7 | 0.733 | 0.787 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain |
199 |
SUB1 | interactor | 9 | 0.321 | 11.745 | Dehydrin (PF00257, IPR000167): Dehydrin PC4 (PF02229, IPR003173): Transcriptional Coactivator p15 (PC4) |
200 |
SYK | suppressor | 8 | 0.524 | 2.392 | Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain |
201 |
TAF4 | protein found in more fusions | 8 | 0.476 | 4.458 | TAF4 (PF05236, IPR007900): Transcription initiation factor TFIID component TAF4 family TAFH (PF07531, IPR003894, SM00549): NHR1 homology to TAF TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit DUF3729 (PF12526, IPR022202): Protein of unknown function (DUF3729) |
202 |
TAL1 | oncoprotein | 14 | 0.449 | 17.808 | HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain SelK_SelG (PF10961, IPR024491): Selenoprotein SelK_SelG |
203 |
TBP | interactor | 31 | 0.301 | 145.481 | TBP (PF00352, IPR000814): Transcription factor TFIID (or TATA-binding protein, TBP) EPL1 (PF10513, IPR019542): Enhancer of polycomb-like Med3 (PF11593, IPR020998): Mediator complex subunit 3 fungal |
204 |
TBX21 | oncoprotein | 5 | 0.500 | 2.586 | T-box (PF00907, IPR001699, SM00425): T-box T-box_assoc (PF16176, IPR032385): T-box transcription factor-associated |
205 |
TFAP2A | suppressor | 14 | 0.637 | 5.446 | TF_AP-2 (PF03299, IPR013854): Transcription factor AP-2 CYYR1 (PF10873, IPR022640): Cysteine and tyrosine-rich protein 1 Peptidase_Prp (PF04327): Cysteine protease Prp |
206 |
TFAP4 | oncoprotein | 13 | 0.423 | 24.213 | DivIC (PF04977, IPR007060): Septum formation initiator HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain DUF2407 (PF10302, IPR019413): DUF2407 ubiquitin-like domain |
207 |
TIMELESS | interactor | 1 | 0 | 0 | Myc_N (PF01056, IPR012682): Myc amino-terminal region TIMELESS (PF04821, IPR006906): Timeless protein TIMELESS_C (PF05029, IPR007725): Timeless protein C terminal region Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain |
208 |
TLX3 | oncoprotein | 2 | 1.000 | 0 | Homeobox (PF00046, IPR001356, SM00389): Homeobox domain |
209 |
TNFRSF11A | oncoprotein | 2 | 1.000 | 0 | Abi (PF02517, IPR003675): CAAX protease self-immunity DAG1 (PF05454, IPR008465): Dystroglycan (Dystrophin-associated glycoprotein 1) KIX (PF02172, IPR003101): KIX domain TNFR_c6 (PF00020, IPR001368, SM00208): TNFR/NGFR cysteine-rich region |
210 |
TP53 | suppressor | 79 | 0.193 | 1257.822 | DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region P53 (PF00870, IPR011615): P53 DNA-binding domain P53_tetramer (PF07710, IPR010991): P53 tetramerisation motif |
211 |
TPI1 | interactor | 3 | 1.000 | 0 | TIM (PF00121, IPR000652): Triosephosphate isomerase |
212 |
TPM1 | protein found in more fusions | 14 | 0.474 | 26.956 | Tropomyosin (PF00261, IPR000533): Tropomyosin Tropomyosin_1 (PF12718, IPR000533): Tropomyosin like |
213 |
TPM2 | protein found in more fusions | 12 | 0.455 | 17.071 | DASH_Spc19 (PF08287, IPR013251): Spc19 Tropomyosin (PF00261, IPR000533): Tropomyosin Tropomyosin_1 (PF12718, IPR000533): Tropomyosin like |
214 |
TPM3 | oncoprotein | 12 | 0.618 | 10.702 | Tropomyosin (PF00261, IPR000533): Tropomyosin Tropomyosin_1 (PF12718, IPR000533): Tropomyosin like |
215 |
TPM4 | oncoprotein | 9 | 0.778 | 3.556 | Tropomyosin (PF00261, IPR000533): Tropomyosin Tropomyosin_1 (PF12718, IPR000533): Tropomyosin like |
216 |
TTN | interactor | 5 | 0.400 | 1.737 | DUF11 (PF01345, IPR001434): Domain of unknown function DUF11 fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region I-set (PF07679, IPR013098): Immunoglobulin I-set domain Pkinase (PF00069, IPR000719): Protein kinase domain PPAK (PF02818, IPR004168): PPAK motif Titin_Z (PF09042, IPR015129): Titin Z V-set (PF07686, IPR013106): Immunoglobulin V-set domain Y_Y_Y (PF07495, IPR011123): Y_Y_Y domain DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369) Ig_3 (PF13927): Immunoglobulin domain |
217 |
TUBA1B | interactor | 4 | 0.500 | 3.000 | Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain |
218 |
TUBB3 | interactor | 4 | 0.500 | 2.333 | Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain |
219 |
TUBB4A | interactor | 2 | 1.000 | 0 | Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain |
220 |
USP39 | oncoprotein | 2 | 1.000 | 0 | UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase zf-UBP (PF02148, IPR001607, SM00290): Zn-finger in ubiquitin-hydrolases and other protein |
221 |
VHL | suppressor | 29 | 0.339 | 95.222 | Trypan_PARP (PF05887, IPR008882): Procyclic acidic repetitive protein (PARP) VHL (PF01847, IPR022772): von Hippel-Lindau disease tumour suppressor protein VHL_C (PF17211): VHL box domain |
222 |
VIM | suppressor | 12 | 0.345 | 21.354 | Filament (PF00038, IPR001664): Intermediate filament protein Filament_head (PF04732, IPR006821): Intermediate filament head (DNA binding) region |
223 |
YY1 | protein found in more fusions | 29 | 0.339 | 100.760 | zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_4 (PF13894): C2H2-type zinc finger Keratin_2_tail (PF16210, IPR032449): Keratin type II cytoskeletal 1 tail |
224 |
ZBTB2 | interactor | 5 | 1.000 | 0 | BTB (PF00651, IPR013069, SM00225): BTB/POZ domain zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-met (PF12874): Zinc-finger of C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain |
225 |
ZBTB7A | interactor | 17 | 0.500 | 18.885 | BTB (PF00651, IPR013069, SM00225): BTB/POZ domain GAGA (PF09237, IPR015318): GAGA factor zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_4 (PF13894): C2H2-type zinc finger |
226 |
ZBTB7B | interactor | 9 | 0.607 | 3.497 | BTB (PF00651, IPR013069, SM00225): BTB/POZ domain CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal GAGA (PF09237, IPR015318): GAGA factor SMN (PF06003, IPR010304): Survival motor neuron protein (SMN) zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain |