Find Fusion Network

Visualization interactions

Powered by Cytoscape Web for: parental proteins SP1 (from a repository: Fri Nov 11 23:10:51 2016)

Examples AFF1 MLL ACTN4 + MLLAFF1 + MLLALK + MSNALK + TFGALK + TPM3ALK + TPM4ASXL2 + KAT6AATF1 + FUSBCR + ABL1BCR + FGFR1CCND1 + TACSTD2CD74 + ROS1CDK6 + MLLCOL1A1 + PDGFBCREB3L2 + PPARGCREB3L2 + FUSCREBBP + KAT6ADAZAP1 + MEF2DELL + MLLEPS15 + MLLERG + EWSR1ERG + FUSERG + TMPRSS2ETV5 + TMPRSS2ETV6 + ABL1ETV6 + NTRK3ETV6 + PAX5EWSR1 + FLI1EWSR1 + WT1FOXO1 + PAX3FOXP1 + PAX5FRYL + MLLGAS7 + MLLGMPS + MLLGOLGA5 + RETHOOK3 + RETHOXC13 + NUP98HOXD13 + NUP98MECOM + RUNX1MKL1 + RBM15MLL + MLLT1MLL + MLLT4MLL + MLLT10MLL + PICALMMLLT10 + PICALMNCOA1 + PAX3NIN + PDGFRBNPM1 + RARANRG1 + ODZ4NTRK1 + TFGNUMA1 + RARANUP98 + PHF23PAX5 + ZNF521PBX1 + TCF3RET + TRIM27ROS1 + SLC34A2PML + RARAPRKAR1A + RARAPRKAR1A + RETRUNX1 + RUNX1T1RUNX1 + SH3D19	Cytoscape Web will replace the contents your graph	PPI Properties: Click on nodes or edges
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Statistics and Network structure information

Statistic of PPI Value(s) The number of interactors (fusion and proteins) 226 The number (and %) of the onco-proteins 92 (40.71 %) The number (and %) of the tumor suppressors 58 (25.66 %) Total number of binary PPIs (saturation %) 1876 (7.38 %) The number (and %) of affected PPIs 226 (12.05 %) The number of possible different fusions 55 PPI diameter 2 PPI radius 1 The average degree of PPI 15.743 Assortativity coefficient -0.2430 The network average Clustering coefficient 0.496 The number (and %) of a zero Clustering coefficients 12 (5.31 %) The number (and %) of a zero Betweenness Centrality 32 (14.16 %)

ACTIVE INTERACTORS

List of the fusions
PPI for parental proteins: SP1	All fusions : CN359274;
Proteins found in more fusions	CTBP1 (see 2 fusions); SYK (see 1 fusions); SMAD4 (see 2 fusions); MAPK1 (see 1 fusions); TPM2/MYH9 (see 1 fusions); NPM1 (see 1 fusions); PRKCD (see 2 fusions); NAP1L1 (see 3 fusions); VHL (see 1 fusions); MYC (see 1 fusions); SREBF2 (see 2 fusions); TPM2 (see 1 fusions); PRKDC (see 3 fusions); ACTG1 (see 4 fusions); RARA (see 4 fusions); HTT (see 1 fusions); RXRA (see 2 fusions); TAF4 (see 4 fusions); SMARCC1 (see 2 fusions); PARP1 (see 1 fusions); EP300 (see 1 fusions); HCFC1 (see 2 fusions); DDX5 (see 1 fusions); CCND1 (see 1 fusions); MYO6 (see 3 fusions); STRAP (see 2 fusions); TP53 (see 3 fusions); MSX1 (see 1 fusions); TPM1 (see 2 fusions); RARA/PML (see 20 fusions); POU2F1 (see 1 fusions); AHR (see 1 fusions); TPM2/TPM3 (see 1 fusions); HSP90AA1 (see 2 fusions); SFPQ (see 6 fusions); NCL/NAP1L1 (see 1 fusions); TPM2/TPM1 (see 1 fusions); HDAC4 (see 1 fusions); NFKB1 (see 2 fusions); HINT1 (see 3 fusions); YY1 (see 2 fusions); MAPK14 (see 1 fusions); SP1 (see 1 fusions); CREBBP (see 5 fusions); STAT3 (see 2 fusions); NF2 (see 1 fusions); RARA/NPM1 (see 1 fusions); MYOD1 (see 1 fusions); EPAS1 (see 1 fusions); PML (see 4 fusions); MEIS2 (see 1 fusions); PSMC5 (see 2 fusions); NCL (see 3 fusions); SMAD3 (see 3 fusions);

List of active interactors

#	Name	Type	Number of PPI (degree)	Clustering Coefficient	Betweenness Centrality	Domains (Pfam, InterPro, SMART): description
1	SP1	parental protein	226	0.062	31799.432	zf-Di19 (PF05605, IPR008598): Drought induced 19 protein (Di19), zinc-binding Herpes_capsid (PF06112, IPR009299): Gammaherpesvirus capsid protein zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type Miga (PF10265, IPR019392): Mitoguardin zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
2	AATF	oncoprotein	10	0.489	5.754	DARPP-32 (PF05395, IPR008466): Protein phosphatase inhibitor 1/DARPP-32 RR_TM4-6 (PF06459, IPR009460): Ryanodine Receptor TM 4-6 TRAUB (PF08164, IPR012617): Apoptosis-antagonizing transcription factor, C-terminal Vif (PF00559, IPR000475): Retroviral Vif (Viral infectivity) protein AATF-Che1 (PF13339, IPR025160): Apoptosis antagonizing transcription factor
3	ACTBL2	interactor	6	0.667	1.819	Actin (PF00022, IPR004000, SM00268): Actin
4	ACTC1	interactor	6	0.533	3.752	Actin (PF00022, IPR004000, SM00268): Actin
5	ACTG1	protein found in more fusions	11	0.622	5.546	Actin (PF00022, IPR004000, SM00268): Actin
6	AHR	suppressor	16	0.514	19.444	HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain PAS (PF00989, IPR013767, SM00091): PAS fold PAS_3 (PF08447, IPR013655): PAS fold PAS_4 (PF08448, IPR013656): PAS fold
7	ANXA2	interactor	11	0.618	9.307	Annexin (PF00191, IPR018502, SM00335): Annexin
8	AR	oncoprotein	46	0.297	282.468	Androgen_recep (PF02166, IPR001103): Androgen receptor zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
9	ARHGAP21	interactor	5	0.700	2.000	PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) RhoGAP (PF00620, IPR000198, SM00324): RhoGAP domain MAJIN (PF15077, IPR027816): Membrane-anchored junction protein PH_9 (PF15410): Pleckstrin homology domain
10	ARNT	oncoprotein	9	0.639	2.390	HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain PAS (PF00989, IPR013767, SM00091): PAS fold PAS_11 (PF14598): PAS domain PRAS (PF15798, IPR026682): Proline-rich AKT1 substrate 1
11	ATF6	interactor	8	0.476	4.490	bZIP_1 (PF00170, IPR004827): bZIP transcription factor DUF2749 (PF10907, IPR024475): Protein of unknown function (DUF2749)
12	ATF7IP	oncoprotein	6	0.467	4.034	TCP (PF03634, IPR005333): TCP family transcription factor DUF2951 (PF11166, IPR021337): Protein of unknown function (DUF2951) ALMT (PF11744, IPR020966): Aluminium activated malate transporter ATF7IP_BD (PF16788, IPR031870): ATF-interacting protein binding domain fn3_4 (PF16794, IPR003961): Fibronectin-III type domain
13	ATF7IP2	interactor	2	1.000	0	ATF7IP_BD (PF16788, IPR031870): ATF-interacting protein binding domain fn3_4 (PF16794, IPR003961): Fibronectin-III type domain
14	BCL11B	oncoprotein	8	0.607	3.675	FYVE (PF01363, IPR000306, SM00064): FYVE zinc finger zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-CCHC_2 (PF13696, IPR025829): Zinc knuckle zf-H2C2_5 (PF13909): C2H2-type zinc-finger domain
15	BCOR	oncoprotein	9	0.786	1.024	Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) BCOR (PF15808, IPR031628): BCL-6 co-repressor, non-ankyrin-repeat region PUFD (PF16553, IPR032365): BCORL-PCGF1-binding domain
16	BRCA1	suppressor	64	0.224	809.884	BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger) BRCT_assoc (PF12820, IPR025994): Serine-rich domain associated with BRCT
17	BRCA2	suppressor	8	0.750	1.995	BRCA-2_helical (PF09169, IPR015252): BRCA2, helical BRCA-2_OB1 (PF09103, IPR015187): BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 BRCA-2_OB3 (PF09104, IPR015188): BRCA2, oligonucleotide/oligosaccharide-binding, domain 3 BRCA2 (PF00634, IPR002093): BRCA2 repeat Tower (PF09121, IPR015205): Tower
18	BTRC	oncoprotein	29	0.262	129.996	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Beta-TrCP_D (PF12125, IPR021977, SM01028): D domain of beta-TrCP ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain F-box-like (PF12937, IPR001810): F-box-like
19	CALM1	interactor	17	0.257	56.978	EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
20	CAPZB	interactor	12	0.439	23.762	Cytochrom_B562 (PF07361, IPR009155): Cytochrome b562 F_actin_cap_B (PF01115, IPR001698): F-actin capping protein, beta subunit
21	CASP3	interactor	15	0.319	32.679	Peptidase_C14 (PF00656, IPR011600): Caspase domain
22	CASP6	interactor	5	0.667	0.667	Peptidase_C14 (PF00656, IPR011600): Caspase domain
23	CASP7	interactor	6	0.700	0.792	Peptidase_C14 (PF00656, IPR011600): Caspase domain PRIMA1 (PF16101): Proline-rich membrane anchor 1
24	CBX5	suppressor	20	0.240	80.390	Chromo (PF00385, IPR023780, SM00298): Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow (PF01393, IPR008251, SM00300): Chromo shadow domain
25	CCNA1	interactor	10	0.667	4.065	Cyclin_C (PF02984, IPR004367): Cyclin, C-terminal domain Cyclin_N (PF00134, IPR006671): Cyclin, N-terminal domain Cyclin_N2 (PF16500, IPR032447): N-terminal region of cyclin_N
26	CCNA2	oncoprotein	21	0.442	43.923	Cyclin_C (PF02984, IPR004367): Cyclin, C-terminal domain Cyclin_N (PF00134, IPR006671): Cyclin, N-terminal domain Cyclin_N2 (PF16500, IPR032447): N-terminal region of cyclin_N
27	CCNB1	oncoprotein	11	0.691	4.132	Adeno_E1A (PF02703, IPR003853): Early E1A protein Cyclin_C (PF02984, IPR004367): Cyclin, C-terminal domain Cyclin_N (PF00134, IPR006671): Cyclin, N-terminal domain
28	CCND1	oncoprotein	20	0.550	14.395	Cyclin_C (PF02984, IPR004367): Cyclin, C-terminal domain Cyclin_N (PF00134, IPR006671): Cyclin, N-terminal domain
29	CDC42BPB	interactor	1	0	0	CNH (PF00780, IPR001180, SM00036): CNH domain DMPK_coil (PF08826, IPR014930): DMPK coiled coil domain like PBD (PF00786, IPR000095, SM00285): P21-Rho-binding domain PH (PF00169, IPR001849, SM00233): PH domain Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein Uso1_p115_C (PF04871, IPR006955): Uso1 / p115 like vesicle tethering protein, C terminal region XkdW (PF09636, IPR019094): XkdW protein C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain) DUF3450 (PF11932, IPR016866): Protein of unknown function (DUF3450) KELK (PF15796, IPR031597): KELK-motif containing domain of MRCK Ser/Thr protein kinase
30	CDK1	oncoprotein	21	0.458	39.833	Pkinase (PF00069, IPR000719): Protein kinase domain
31	CDK2	suppressor	67	0.170	1089.969	Kdo (PF06293, IPR010440): Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase (PF00069, IPR000719): Protein kinase domain
32	CDK4	oncoprotein	15	0.448	16.700	Pkinase (PF00069, IPR000719): Protein kinase domain
33	CDKN2A	suppressor	27	0.333	105.131	Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_5 (PF13857): Ankyrin repeats (many copies)
34	CEBPB	oncoprotein	26	0.560	29.465	RhlB (PF12300, IPR022077): ATP-dependent RNA helicase RhlB FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
35	CNTLN	interactor	3	1.000	0	APG6 (PF04111, IPR007243): Autophagy protein Apg6 ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16) CALCOCO1 (PF07888, IPR012852): Calcium binding and coiled-coil domain (CALCOCO1) like DUF745 (PF05335, IPR007999): Protein of unknown function (DUF745) HrpB7 (PF09486, IPR013392): Bacterial type III secretion protein (HrpB7) Cnn_1N (PF07989, IPR012943): Centrosomin N-terminal motif 1 Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein Spc24 (PF08286, IPR013252): Spc24 subunit of Ndc80 TSC22 (PF01166, IPR000580): TSC-22/dip/bun family Uso1_p115_C (PF04871, IPR006955): Uso1 / p115 like vesicle tethering protein, C terminal region Cep57_CLD_2 (PF14197, IPR025925): Centrosome localisation domain of PPC89 PRKG1_interact (PF15898, IPR031775): cGMP-dependent protein kinase interacting domain
36	COL3A1	oncoprotein	1	0	0	COLFI (PF01410, IPR000885, SM00038): Fibrillar collagen C-terminal domain Collagen (PF01391, IPR008160): Collagen triple helix repeat (20 copies) DUF1860 (PF08949, IPR015044): Domain of unknown function (DUF1860) VWC (PF00093, IPR001007, SM00214): von Willebrand factor type C domain
37	CREBBP	suppressor	64	0.255	656.485	Creb_binding (PF09030, IPR014744): Creb binding DUF902 (PF06001, IPR010303): Domain of Unknown Function (DUF902) Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region KIX (PF02172, IPR003101): KIX domain MAS20 (PF02064, IPR002056): MAS20 protein import receptor TPX2 (PF06886, IPR027329): Targeting protein for Xklp2 (TPX2) zf-TAZ (PF02135, IPR000197, SM00551): TAZ zinc finger ANAPC_CDC26 (PF10471, IPR018860): Anaphase-promoting complex APC subunit CDC26 HAT_KAT11 (PF08214, IPR013178): Histone acetylation protein Bromodomain (PF00439, IPR001487, SM00297): Bromodomain ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type DUF3729 (PF12526, IPR022202): Protein of unknown function (DUF3729) DUF4834 (PF16118, IPR032272): Domain of unknown function (DUF4834)
38	CRX	interactor	4	0.833	0.500	TF_Otx (PF03529, IPR013851): Otx1 transcription factor Homeobox (PF00046, IPR001356, SM00389): Homeobox domain SUIM_assoc (PF16619): Unstructured region C-term to UIM in Ataxin3
39	CTBP1	protein found in more fusions	21	0.442	39.286	2-Hacid_dh_C (PF02826, IPR006140): D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Cellsynth_D (PF03500, IPR022798): Cellulose synthase subunit D
40	CTCFL	suppressor	3	0.667	0.111	PHD (PF00628, IPR019787, SM00249): PHD-finger zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_4 (PF13894): C2H2-type zinc finger zf-H2C2_5 (PF13909): C2H2-type zinc-finger domain
41	CTNNB1	oncoprotein	37	0.294	197.660	Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat Atx10homo_assoc (PF09759, IPR019156): Spinocerebellar ataxia type 10 protein domain DUF3361 (PF11841, IPR024574): Domain of unknown function (DUF3361) HEAT_EZ (PF13513): HEAT-like repeat
42	DBN1	oncoprotein	23	0.304	100.969	Pinin_SDK_memA (PF04696, IPR006786): pinin/SDK/memA/ protein conserved region Cofilin_ADF (PF00241, IPR002108, SM00102): Cofilin/tropomyosin-type actin-binding protein CAF-1_p150 (PF11600): Chromatin assembly factor 1 complex p150 subunit, N-terminal MSA-2c (PF12238, IPR021060): Merozoite surface antigen 2c
43	DCAF6	interactor	5	0.500	1.310	Herpes_pp85 (PF04637, IPR006731): Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat DUF3408 (PF11888, IPR021823): Protein of unknown function (DUF3408) ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain ATAD4 (PF15321, IPR028237): ATPase family AAA domain containing 4 MRI (PF15325, IPR028278): Modulator of retrovirus infection WD40_like (PF17005, IPR031544): WD40-like domain
44	DDX3X	suppressor	13	0.410	23.955	DEAD (PF00270, IPR011545): DEAD/DEAH box helicase DUF755 (PF05501, IPR008474): Domain of unknown function (DUF755) Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
45	DDX5	oncoprotein	21	0.532	19.401	DEAD (PF00270, IPR011545): DEAD/DEAH box helicase P68HR (PF08061, IPR012587): P68HR (NUC004) repeat ResIII (PF04851, IPR006935): Type III restriction enzyme, res subunit Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
46	DES	interactor	3	0.667	0.500	Filament (PF00038, IPR001664): Intermediate filament protein Filament_head (PF04732, IPR006821): Intermediate filament head (DNA binding) region HAUS-augmin3 (PF14932, IPR032733): HAUS augmin-like complex subunit 3
47	DNMT1	suppressor	18	0.507	24.227	BAH (PF01426, IPR001025, SM00439): BAH domain DMAP_binding (PF06464, IPR010506, SM01137): DMAP1-binding Domain DNA_methylase (PF00145, IPR001525): C-5 cytosine-specific DNA methylase zf-CXXC (PF02008, IPR002857): CXXC zinc finger domain DNMT1-RFD (PF12047, IPR022702): Cytosine specific DNA methyltransferase replication foci domain
48	E2F1	suppressor	30	0.343	123.028	Cellsynth_D (PF03500, IPR022798): Cellulose synthase subunit D E2F_TDP (PF02319, IPR003316): E2F/DP family winged-helix DNA-binding domain E2F_CC-MB (PF16421, IPR032198): E2F transcription factor CC-MB domain
49	EGR1	suppressor	11	0.455	16.497	zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type DUF3432 (PF11914, IPR021839): Domain of unknown function (DUF3432) DUF3446 (PF11928, IPR021849): Domain of unknown function (DUF3446) zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
50	ELF1	interactor	5	0.700	1.133	Ets (PF00178, IPR000418, SM00413): Ets-domain PAPA-1 (PF04795, IPR006880): PAPA-1-like conserved region Elf-1_N (PF12310, IPR022084): Transcription factor protein N terminal
51	EP300	oncoprotein	81	0.200	1295.329	Creb_binding (PF09030, IPR014744): Creb binding DUF902 (PF06001, IPR010303): Domain of Unknown Function (DUF902) Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region KIX (PF02172, IPR003101): KIX domain RR_TM4-6 (PF06459, IPR009460): Ryanodine Receptor TM 4-6 TPX2 (PF06886, IPR027329): Targeting protein for Xklp2 (TPX2) zf-TAZ (PF02135, IPR000197, SM00551): TAZ zinc finger HAT_KAT11 (PF08214, IPR013178): Histone acetylation protein Bromodomain (PF00439, IPR001487, SM00297): Bromodomain ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type
52	EPAS1	suppressor	19	0.438	26.264	Corona_I (PF03187, IPR004876): Corona nucleocapsid I protein HIF-1a_CTAD (PF08778, IPR014887): HIF-1 alpha C terminal transactivation domain HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain PAS (PF00989, IPR013767, SM00091): PAS fold HIF-1 (PF11413, IPR021537): Hypoxia-inducible factor-1 PAS_11 (PF14598): PAS domain
53	ESR1	suppressor	70	0.201	1038.736	Oest_recep (PF02159, IPR001292): Oestrogen receptor zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor ESR1_C (PF12743, IPR024736): Oestrogen-type nuclear receptor final C-terminal
54	ESR2	suppressor	10	0.667	2.661	zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor ERbeta_N (PF12497, IPR021064): Estrogen receptor beta
55	ESRRA	oncoprotein	6	0.467	4.761	zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
56	ESRRB	suppressor	5	0.500	3.722	zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
57	ESRRG	oncoprotein	4	1.000	0	zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
58	ETS1	oncoprotein	16	0.517	20.479	Ets (PF00178, IPR000418, SM00413): Ets-domain SAM_PNT (PF02198, IPR003118, SM00251): Sterile alpha motif (SAM)/Pointed domain
59	FEZF1	interactor	1	0	0	zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
60	FGFR1OP2	oncoprotein	1	0	0	Cauli_AT (PF03233, IPR004917): Aphid transmission protein DUF837 (PF05769, IPR008555): Protein of unknown function (DUF837) Snapin_Pallidin (PF14712, IPR028119): Snapin/Pallidin
61	FHL1	suppressor	10	0.556	9.387	LIM (PF00412, IPR001781, SM00132): LIM domain zf-FCS (PF06467, IPR010507): MYM-type Zinc finger with FCS sequence motif
62	FKBP15	interactor	1	0	0	Filament (PF00038, IPR001664): Intermediate filament protein FKBP_C (PF00254, IPR001179): FKBP-type peptidyl-prolyl cis-trans isomerase NPV_P10 (PF05531, IPR008702): Nucleopolyhedrovirus P10 protein SMN (PF06003, IPR010304): Survival motor neuron protein (SMN) Spc24 (PF08286, IPR013252): Spc24 subunit of Ndc80 WH1 (PF00568, IPR000697, SM00461): WH1 domain SOSSC (PF15925, IPR031821): SOSS complex subunit C TolA_bind_tri (PF16331, IPR032519): TolA binding protein trimerisation
63	FOXM1	oncoprotein	9	0.611	2.949	EspF (PF04806, IPR006891): EspF protein repeat Forkhead (PF00250, IPR001766, SM00339): Forkhead domain
64	GABPA	interactor	6	0.867	0.571	Ets (PF00178, IPR000418, SM00413): Ets-domain SAM_PNT (PF02198, IPR003118, SM00251): Sterile alpha motif (SAM)/Pointed domain GABP-alpha (PF11620, IPR024668): GA-binding protein alpha chain Wap1 (PF16997, IPR031550): Wap1 domain
65	GAK	oncoprotein	6	0.667	1.590	DnaJ (PF00226, IPR001623, SM00271): DnaJ domain DSPc (PF00782, IPR020422, SM00195): Dual specificity phosphatase, catalytic domain Pkinase (PF00069, IPR000719): Protein kinase domain PTEN_C2 (PF10409, IPR014020): C2 domain of PTEN tumour-suppressor protein
66	GATA1	oncoprotein	13	0.423	16.618	GATA (PF00320, IPR000679, SM00401): GATA zinc finger Vps36-NZF-N (PF16988, IPR031558): Vacuolar protein sorting 36 NZF-N zinc-finger domain
67	GATA3	oncoprotein	9	0.333	10.820	GATA (PF00320, IPR000679, SM00401): GATA zinc finger Vps36-NZF-N (PF16988, IPR031558): Vacuolar protein sorting 36 NZF-N zinc-finger domain
68	GATA4	suppressor	6	0.400	3.065	Apidaecin (PF00807, IPR004828): Apidaecin GATA-N (PF05349, IPR008013): GATA-type transcription activator, N-terminal DUF2387 (PF09526, IPR012658): Probable metal-binding protein (DUF2387) GATA (PF00320, IPR000679, SM00401): GATA zinc finger
69	GATA6	oncoprotein	2	1.000	0	GATA-N (PF05349, IPR008013): GATA-type transcription activator, N-terminal OrfB_Zn_ribbon (PF07282, IPR010095): Putative transposase DNA-binding domain DUF2387 (PF09526, IPR012658): Probable metal-binding protein (DUF2387) GATA (PF00320, IPR000679, SM00401): GATA zinc finger
70	GBP1	suppressor	1	0	0	GBP (PF02263, IPR015894): Guanylate-binding protein, N-terminal domain GBP_C (PF02841, IPR003191): Guanylate-binding protein, C-terminal domain
71	HBZ	interactor	1	0	0	Globin (PF00042, IPR000971): Globin
72	HCFC1	protein found in more fusions	14	0.436	14.241	fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain Kelch_1 (PF01344, IPR006652, SM00612): Kelch motif Kelch_3 (PF13415): Galactose oxidase, central domain Kelch_5 (PF13854): Kelch motif zf-tcix (PF14952, IPR029269): Putative treble-clef, zinc-finger, Zn-binding
73	HDAC1	suppressor	73	0.227	907.513	FSAP_sig_propep (PF03032, IPR004275): Frog skin active peptide family signal and propeptide Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
74	HDAC2	suppressor	47	0.282	290.702	Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain NARP1 (PF12569, IPR021183): NMDA receptor-regulated protein 1
75	HDAC3	suppressor	48	0.254	355.856	Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
76	HDAC4	oncoprotein	32	0.256	160.522	Borrelia_P83 (PF05262, IPR007926): Borrelia P83/100 protein Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit HDAC4_Gln (PF12203, IPR024643): Glutamine rich N terminal domain of histone deacetylase 4
77	HIC1	suppressor	7	0.467	2.619	BTB (PF00651, IPR013069, SM00225): BTB/POZ domain zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_4 (PF13894): C2H2-type zinc finger
78	HIF1A	suppressor	27	0.547	34.432	Dicty_REP (PF05086, IPR007778): Dictyostelium (Slime Mold) REP protein HIF-1a_CTAD (PF08778, IPR014887): HIF-1 alpha C terminal transactivation domain HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain PAS (PF00989, IPR013767, SM00091): PAS fold PAS_3 (PF08447, IPR013655): PAS fold HIF-1 (PF11413, IPR021537): Hypoxia-inducible factor-1
79	HINT1	suppressor	6	0.600	0.817	HIT (PF01230, IPR001310): HIT domain
80	HLTF	suppressor	4	0.667	0.143	HIRAN (PF08797, IPR014905, SM00910): HIRAN domain SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
81	HMGA1	oncoprotein	22	0.351	63.209	AT_hook (PF02178, IPR017956, SM00384): AT hook motif DUF2239 (PF09998, IPR018715): Uncharacterized protein conserved in bacteria (DUF2239)
82	HNF4A	suppressor	18	0.463	25.388	zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
83	HOXC11	oncoprotein	5	0.400	2.625	DUF3528 (PF12045, IPR021918): Protein of unknown function (DUF3528)
84	HSP90AA1	oncoprotein	40	0.254	265.693	HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HSP90 (PF00183, IPR001404): Hsp90 protein
85	HSPA9	oncoprotein	8	0.571	5.297	HSP70 (PF00012, IPR013126): Hsp70 protein
86	HTT	protein found in more fusions	14	0.385	27.357	HEAT (PF02985, IPR000357): HEAT repeat SPX (PF03105, IPR004331): SPX domain TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit DUF3652 (PF12372, IPR024613): Huntingtin protein region Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region HEAT_EZ (PF13513): HEAT-like repeat HEAT_2 (PF13646): HEAT repeats
87	IFI16	suppressor	13	0.385	21.409	HIN (PF02760, IPR004021): HIN-200/IF120x domain PYRIN (PF02758, IPR004020): PAAD/DAPIN/Pyrin domain Mitofilin (PF09731, IPR019133): Mitochondrial inner membrane protein
88	IL1B	oncoprotein	2	1.000	0	IL1 (PF00340, IPR000975, SM00125): Interleukin-1 / 18 IL1_propep (PF02394, IPR003502): Interleukin-1 propeptide
89	JUN	oncoprotein	43	0.355	202.035	bZIP_1 (PF00170, IPR004827): bZIP transcription factor Jun (PF03957, IPR005643): Jun-like transcription factor
90	KIF1A	interactor	5	0.500	0.566	FHA (PF00498, IPR000253, SM00240): FHA domain IncA (PF04156, IPR007285): IncA protein PH (PF00169, IPR001849, SM00233): PH domain Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein Kinesin (PF00225, IPR001752, SM00129): Kinesin motor domain KIF1B (PF12423, IPR022140): Kinesin protein 1B Sox_N (PF12444, IPR022151): Sox developmental protein N terminal DUF3694 (PF12473, IPR022164): Kinesin protein Kinesin_assoc (PF16183, IPR032405): Kinesin-associated
91	KLF10	suppressor	3	0.667	0.222	zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain AAA_33 (PF13671): AAA domain
92	KLF4	suppressor	12	0.561	11.646	zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
93	KLF6	suppressor	4	0.500	0.689	zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
94	KLF9	interactor	3	0.667	0.333	zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
95	LDB1	oncoprotein	5	0.700	0.802	LIM_bind (PF01803): LIM-domain binding protein
96	LMO2	oncoprotein	12	0.327	24.881	CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal LIM (PF00412, IPR001781, SM00132): LIM domain
97	LMO7	oncoprotein	7	0.571	4.633	CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain DUF1764 (PF08576, IPR013885): Eukaryotic protein of unknown function (DUF1764) LIM (PF00412, IPR001781, SM00132): LIM domain PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) DUF2072 (PF09845, IPR018645): Zn-ribbon containing protein AAA_23 (PF13476): AAA domain DUF4757 (PF15949, IPR031865): Domain of unknown function (DUF4757)
98	LUZP1	interactor	5	0.700	1.400	Trimer_CC (PF08954, IPR015049, SM01167): Trimerisation motif DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972) EMP24_GP25L (PF01105, IPR009038): emp24/gp25L/p24 family/GOLD Fzo_mitofusin (PF04799, IPR006884): fzo-like conserved region MerR-DNA-bind (PF09278, IPR015358): MerR, DNA binding Neur_chan_memb (PF02932, IPR006029): Neurotransmitter-gated ion-channel transmembrane region TMA7 (PF09072, IPR015157): Translation machinery associated TMA7 HD_assoc (PF13286, IPR026875): Phosphohydrolase-associated domain DUF4298 (PF14131, IPR025384): Domain of unknown function (DUF4298) PRKG1_interact (PF15898, IPR031775): cGMP-dependent protein kinase interacting domain
99	MAPK1	oncoprotein	33	0.339	140.323	Pkinase (PF00069, IPR000719): Protein kinase domain
100	MAPK14	oncoprotein	17	0.400	36.412	Pkinase (PF00069, IPR000719): Protein kinase domain
101	MAPK3	oncoprotein	20	0.368	55.531	Pkinase (PF00069, IPR000719): Protein kinase domain
102	MAPK8	oncoprotein	15	0.549	10.211	DUF530 (PF04409, IPR007503): Protein of unknown function (DUF530) Pkinase (PF00069, IPR000719): Protein kinase domain
103	MBD1	interactor	7	0.286	10.675	MBD (PF01429, IPR001739, SM00391): Methyl-CpG binding domain zf-CXXC (PF02008, IPR002857): CXXC zinc finger domain
104	MECP2	interactor	10	0.422	10.386	K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain MBD (PF01429, IPR001739, SM00391): Methyl-CpG binding domain SelP_N (PF04592, IPR007671): Selenoprotein P, N terminal region IHABP4_N (PF16174, IPR032381): Intracellular hyaluronan-binding protein 4 N-terminal
105	MEF2C	oncoprotein	9	0.361	9.972	SRF-TF (PF00319, IPR002100, SM00432): SRF-type transcription factor (DNA-binding and dimerisation domain) HJURP_C (PF12347, IPR022102): Holliday junction regulator protein family C-terminal repeat
106	MEF2D	oncoprotein	10	0.511	6.186	DUF2076 (PF09849, IPR018648): Uncharacterized protein conserved in bacteria (DUF2076) DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360) SRF-TF (PF00319, IPR002100, SM00432): SRF-type transcription factor (DNA-binding and dimerisation domain) HJURP_C (PF12347, IPR022102): Holliday junction regulator protein family C-terminal repeat
107	MEIS2	protein found in more fusions	2	0	0	Homeobox_KN (PF05920, IPR008422): Homeobox KN domain Meis_PKNOX_N (PF16493, IPR032453): N-terminal of Homeobox Meis and PKNOX1
108	MNAT1	oncoprotein	8	0.643	4.651	MAT1 (PF06391, IPR015877): CDK-activating kinase assembly factor MAT1 Mu-like_Com (PF10122, IPR019294): Mu-like prophage protein Com zf-C3HC4_5 (PF17121, IPR001841): Zinc finger, C3HC4 type (RING finger)
109	MSX1	protein found in more fusions	4	1.000	0	Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
110	MYC	oncoprotein	49	0.307	324.536	HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain Myc-LZ (PF02344, IPR003327): Myc leucine zipper domain Myc_N (PF01056, IPR012682): Myc amino-terminal region
111	MYCN	oncoprotein	4	0.833	0.133	HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain Myc_N (PF01056, IPR012682): Myc amino-terminal region
112	MYH10	interactor	5	0.700	1.567	IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif Myosin_N (PF02736, IPR004009): Myosin N-terminal SH3-like domain Myosin_tail_1 (PF01576, IPR002928): Myosin tail Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain)
113	MYH11	oncoprotein	4	0.500	1.567	IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif Myosin_N (PF02736, IPR004009): Myosin N-terminal SH3-like domain Myosin_tail_1 (PF01576, IPR002928): Myosin tail Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain) CC2-LZ (PF16516, IPR032419): Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator
114	MYH14	interactor	6	0.600	2.987	IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif Myosin_N (PF02736, IPR004009): Myosin N-terminal SH3-like domain Myosin_tail_1 (PF01576, IPR002928): Myosin tail Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain)
115	MYH7B	interactor	4	1.000	0	Myosin_N (PF02736, IPR004009): Myosin N-terminal SH3-like domain Myosin_tail_1 (PF01576, IPR002928): Myosin tail YkuI_C (PF10388, IPR018842): EAL-domain associated signalling protein domain Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain)
116	MYH9	suppressor	31	0.234	230.830	IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif Myosin_N (PF02736, IPR004009): Myosin N-terminal SH3-like domain Myosin_tail_1 (PF01576, IPR002928): Myosin tail Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain)
117	MYL12A	interactor	7	0.524	5.406	EF-hand_11 (PF08976, IPR015070): EF-hand domain DUF2267 (PF10025, IPR018727): Uncharacterized conserved protein (DUF2267) EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
118	MYL3	interactor	1	0	0	EF-hand_6 (PF13405, IPR002048): EF-hand domain EF-hand_7 (PF13499, IPR011992): EF-hand domain pair EF-hand_8 (PF13833, IPR002048): EF-hand domain pair
119	MYL6B	interactor	3	1.000	0	SapB_1 (PF05184, IPR007856): Saposin-like type B, region 1 EF-hand_6 (PF13405, IPR002048): EF-hand domain EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
120	MYL9	interactor	5	0.800	0.733	UPF0154 (PF03672, IPR005359): Uncharacterised protein family (UPF0154) EF-hand_6 (PF13405, IPR002048): EF-hand domain EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
121	MYO1B	interactor	7	0.857	0.672	IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif Myosin_TH1 (PF06017, IPR010926): Unconventional myosin tail, actin- and lipid-binding RNA_pol (PF00940, IPR002092): DNA-dependent RNA polymerase Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain) AAA_23 (PF13476): AAA domain
122	MYO1C	interactor	13	0.513	18.433	IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif Myosin_TH1 (PF06017, IPR010926): Unconventional myosin tail, actin- and lipid-binding Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain)
123	MYO1E	interactor	5	0.500	2.619	IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif Myosin_TH1 (PF06017, IPR010926): Unconventional myosin tail, actin- and lipid-binding Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain) SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
124	MYO6	protein found in more fusions	9	0.643	3.117	BUD22 (PF09073, IPR015158): BUD22 IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif Myosin_N (PF02736, IPR004009): Myosin N-terminal SH3-like domain Rad9 (PF04139, IPR007268): Rad9 Sec62 (PF03839, IPR004728): Translocation protein Sec62 XhlA (PF10779, IPR019715): Haemolysin XhlA Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain) DUF4887 (PF16228, IPR032615): Domain of unknown function (DUF4887) Myosin-VI_CBD (PF16521, IPR032412): Myosin VI cargo binding domain
125	MYOD1	oncoprotein	18	0.500	21.086	Basic (PF01586, IPR002546, SM00520): Myogenic Basic domain HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain Mfp-3 (PF04202, IPR007328): Foot protein 3 Myf5 (PF12232, IPR022032): Myogenic determination factor 5
126	MYOG	interactor	5	0.500	2.150	Basic (PF01586, IPR002546, SM00520): Myogenic Basic domain HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
127	NAP1L1	protein found in more fusions	9	0.536	3.850	NAP (PF00956, IPR002164): Nucleosome assembly protein (NAP) RNA_pol_3_Rpc31 (PF11705, IPR024661): DNA-directed RNA polymerase III subunit Rpc31 PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
128	NCL	protein found in more fusions	18	0.382	39.689	DUF1754 (PF08555, IPR013865): Eukaryotic family of unknown function (DUF1754) Myc_N (PF01056, IPR012682): Myc amino-terminal region RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) YL1 (PF05764, IPR008895): YL1 nuclear protein Limkain-b1 (PF11608, IPR024582): Limkain b1
129	NCOR1	oncoprotein	30	0.411	75.727	BES1_N (PF05687, IPR008540): BES1/BZR1 plant transcription factor, N-terminal Lamp (PF01299, IPR002000): Lysosome-associated membrane glycoprotein (Lamp) MAS20 (PF02064, IPR002056): MAS20 protein import receptor Neur_chan_memb (PF02932, IPR006029): Neurotransmitter-gated ion-channel transmembrane region Eapp_C (PF10238, IPR019370): E2F-associated phosphoprotein Hid1 (PF12722): High-temperature-induced dauer-formation protein Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain DUF3915 (PF13054, IPR025026): Protein of unknown function (DUF3915) GPS2_interact (PF15784, IPR031557): G-protein pathway suppressor 2-interacting domain DUF4834 (PF16118, IPR032272): Domain of unknown function (DUF4834) RBR (PF17208): RNA binding Region
130	NCOR2	oncoprotein	33	0.411	94.934	CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal MAS20 (PF02064, IPR002056): MAS20 protein import receptor OAD_gamma (PF04277, IPR005899): Oxaloacetate decarboxylase, gamma chain PSK (PF06404, IPR009438): Phytosulfokine precursor protein (PSK) SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360) Gti1_Pac2 (PF09729, IPR018608): Gti1/Pac2 family PRCC (PF10253, IPR018800): Mitotic checkpoint regulator, MAD2B-interacting Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain Spt20 (PF12090, IPR021950): Spt20 family DUF3915 (PF13054, IPR025026): Protein of unknown function (DUF3915) DUF4518 (PF15008, IPR026698): Domain of unknown function (DUF4518) GPS2_interact (PF15784, IPR031557): G-protein pathway suppressor 2-interacting domain DUF4820 (PF16091, IPR032150): Domain of unknown function (DUF4820)
131	NEB	oncoprotein	7	0.381	9.167	Peptidase_M24 (PF00557, IPR001714): Metallopeptidase family M24 Nebulin (PF00880, IPR000900, SM00227): Nebulin repeat Shal-type (PF11601, IPR021645): Shal-type voltage-gated potassium channels, N-terminal DUF3410 (PF11890, IPR024531): Domain of unknown function (DUF3410) DUF3417 (PF11897, IPR024517): Protein of unknown function (DUF3417) G-patch_2 (PF12656, IPR026822): DExH-box splicing factor binding site NFRKB_winged (PF14465, IPR025220): NFRKB Winged Helix-like SH3_9 (PF14604, IPR001452): Variant SH3 domain
132	NEPRO	interactor	2	1.000	0	DUF4477 (PF14780, IPR027951): Domain of unknown function (DUF4477)
133	NF2	suppressor	12	0.291	19.122	ERM (PF00769, IPR011259): Ezrin/radixin/moesin family FERM_C (PF09380, IPR018980): FERM C-terminal PH-like domain FERM_M (PF00373, IPR019748): FERM central domain FERM_N (PF09379, IPR018979): FERM N-terminal domain
134	NFKB1	suppressor	29	0.378	97.300	Death (PF00531, IPR000488, SM00005): Death domain GHMP_kinases_C (PF08544, IPR013750): GHMP kinases C terminal RHD_DNA_bind (PF00554, IPR011539): Rel homology DNA-binding domain Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_4 (PF13637): Ankyrin repeats (many copies) RHD_dimer (PF16179, IPR032397): Rel homology dimerisation domain
135	NFKB2	oncoprotein	9	0.607	4.875	Ank (PF00023, IPR002110, SM00248): Ankyrin repeat Death (PF00531, IPR000488, SM00005): Death domain RHD_DNA_bind (PF00554, IPR011539): Rel homology DNA-binding domain Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_4 (PF13637): Ankyrin repeats (many copies) RHD_dimer (PF16179, IPR032397): Rel homology dimerisation domain
136	NFYA	interactor	18	0.379	48.992	CBFB_NFYA (PF02045, IPR001289): CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B MSP1_C (PF07462, IPR010901): Merozoite surface protein 1 (MSP1) C-terminus FixG_C (PF11614, IPR032879): IG-like fold at C-terminal of FixG, putative oxidoreductase DUF4237 (PF14021, IPR025331): Protein of unknown function (DUF4237)
137	NFYB	interactor	11	0.782	2.595	CBFD_NFYB_HMF (PF00808, IPR003958): Histone-like transcription factor (CBF/NF-Y) and archaeal histone
138	NFYC	interactor	12	0.515	15.268	CBFD_NFYB_HMF (PF00808, IPR003958): Histone-like transcription factor (CBF/NF-Y) and archaeal histone E1-E2_ATPase (PF00122, IPR008250): E1-E2 ATPase Fucose_iso_C (PF02952, IPR015888): L-fucose isomerase, C-terminal domain
139	NKX3-1	suppressor	6	0.467	4.434	Trypan_PARP (PF05887, IPR008882): Procyclic acidic repetitive protein (PARP) Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
140	NPM1	suppressor	35	0.303	203.686	Nucleoplasmin (PF03066): Nucleoplasmin SDA1 (PF05285, IPR007949): SDA1 NPM1-C (PF16276, IPR032569): Nucleophosmin C-terminal domain
141	NR2E1	interactor	5	0.500	2.134	zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
142	NR2F1	oncoprotein	6	0.467	3.905	zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
143	NR5A1	interactor	5	0.600	1.605	zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor PRIMA1 (PF16101): Proline-rich membrane anchor 1
144	NUP62	interactor	9	0.429	8.406	Nsp1_C (PF05064, IPR007758): Nsp1-like C-terminal region GAS (PF13851, IPR025593): Growth-arrest specific micro-tubule binding Nucleoporin_FG2 (PF15967): Nucleoporin FG repeated region
145	NXF1	interactor	39	0.132	400.405	NTF2 (PF02136, IPR002075): Nuclear transport factor 2 (NTF2) domain Tap-RNA_bind (PF09162, IPR015245): Tap, RNA-binding TAP_C (PF03943, IPR005637, SM00804): TAP C-terminal domain LRR_8 (PF13855, IPR001611): Leucine rich repeat
146	ODF2	interactor	6	0.333	6.186	ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16) NAT (PF04768, IPR006855): NAT, N-acetyltransferase, of N-acetylglutamate synthase Invasin_D3 (PF09134, IPR015217): Invasin, domain 3 Mt_ATP-synt_D (PF05873, IPR008689): ATP synthase D chain, mitochondrial (ATP5H) CENP-F_leu_zip (PF10473, IPR019513): Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TMF_TATA_bd (PF12325, IPR022091): TATA element modulatory factor 1 TATA binding TMF_DNA_bd (PF12329, IPR022092): TATA element modulatory factor 1 DNA binding HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1
147	PARP1	suppressor	31	0.414	92.449	BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain PADR1 (PF08063, IPR012982): PADR1 (NUC008) domain PARP (PF00644, IPR012317): Poly(ADP-ribose) polymerase catalytic domain PARP_reg (PF02877, IPR004102): Poly(ADP-ribose) polymerase, regulatory domain WGR (PF05406, IPR008893, SM00773): WGR domain zf-PARP (PF00645, IPR001510): Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region
148	PFDN5	interactor	7	0.524	3.028	Prefoldin (PF02996, IPR004127): Prefoldin subunit UPF0693 (PF16088, IPR032143): UPF0693 family
149	PGR	suppressor	17	0.467	30.392	Prog_receptor (PF02161, IPR000128): Progesterone receptor zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
150	PHOX2A	suppressor	4	1.000	0	Phage_Mu_Gam (PF07352, IPR009951): Bacteriophage Mu Gam like protein Homeobox (PF00046, IPR001356, SM00389): Homeobox domain PRIMA1 (PF16101): Proline-rich membrane anchor 1
151	PIN1	suppressor	25	0.387	85.731	Rotamase (PF00639, IPR000297): PPIC-type PPIASE domain WW (PF00397, IPR001202, SM00456): WW domain
152	PLEC	oncoprotein	6	0.600	2.369	CDC37_N (PF03234, IPR013855, SM01071): Cdc37 N terminal kinase binding CENP-H (PF05837, IPR008426): Centromere protein H (CENP-H) CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972) Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family FUSC (PF04632, IPR006726): Fusaric acid resistance protein family RNA_pol_Rbc25 (PF08292, IPR013238): RNA polymerase III subunit Rpc25 S10_plectin (PF03501, IPR005326): Plectin/S10 domain Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein DUF2229 (PF09989, IPR018709): CoA enzyme activase uncharacterised domain (DUF2229) Plectin (PF00681, IPR001101, SM00250): Plectin repeat YlqD (PF11068, IPR021297): YlqD protein Alanine_zipper (PF11839, IPR021793): Alanine-zipper, major outer membrane lipoprotein DUF3391 (PF11871, IPR021812): Domain of unknown function (DUF3391) DUF4140 (PF13600, IPR025554): N-terminal domain of unknown function (DUF4140)
153	PML	suppressor	38	0.351	159.963	zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger DUF3583 (PF12126, IPR021978): Protein of unknown function (DUF3583) zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
154	POGZ	interactor	6	0.467	4.400	DDE_1 (PF03184, IPR004875): DDE superfamily endonuclease Rubredoxin (PF00301, IPR024935): Rubredoxin HTH_Tnp_Tc5 (PF03221, IPR006600, SM00674): Tc5 transposase DNA-binding domain zf-RRN7 (PF11781, IPR021752): Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain HTH_28 (PF13518): Helix-turn-helix domain zinc_ribbon_4 (PF13717): zinc-ribbon domain zf-C2H2_4 (PF13894): C2H2-type zinc finger zf-C2H2_6 (PF13912, IPR007087): C2H2-type zinc finger zf-RING_5 (PF14634, IPR001841): zinc-RING finger domain
155	POTEE	interactor	2	1.000	0	Actin (PF00022, IPR004000, SM00268): Actin DUF3641 (PF12345, IPR024521): Protein of unknown function (DUF3641) Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) CCDC144C (PF14915): CCDC144C protein coiled-coil region
156	POU2F1	protein found in more fusions	19	0.405	42.966	Pou (PF00157, IPR000327, SM00352): Pou domain - N-terminal to homeobox domain Homeobox (PF00046, IPR001356, SM00389): Homeobox domain DUF3597 (PF12200, IPR022016): Domain of unknown function (DUF3597)
157	PPARG	suppressor	28	0.473	57.082	zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor PPARgamma_N (PF12577, IPR022590): PPAR gamma N-terminal region
158	PPIG	interactor	1	0	0	Ly49 (PF08391, IPR013600): Ly49-like protein, N-terminal region Pro_isomerase (PF00160, IPR002130): Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Med19 (PF10278, IPR019403): Mediator of RNA pol II transcription subunit 19 SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein Apis_Csd (PF11671, IPR021007): Complementary sex determiner protein PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
159	PPP1R13L	oncoprotein	5	1.000	0	Pex14_N (PF04695, IPR006785): Peroxisomal membrane anchor protein (Pex14p) conserved region DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360) Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) SH3_9 (PF14604, IPR001452): Variant SH3 domain PRIMA1 (PF16101): Proline-rich membrane anchor 1
160	PRKCD	suppressor	10	0.611	5.764	Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain)
161	PRKCZ	interactor	8	0.762	0.796	PB1 (PF00564, IPR000270, SM00666): PB1 domain Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain)
162	PRKDC	protein found in more fusions	22	0.505	30.290	FAT (PF02259, IPR003151): FAT domain FATC (PF02260, IPR003152): FATC domain NUC194 (PF08163, IPR012582): NUC194 domain PI3_PI4_kinase (PF00454, IPR000403, SM00146): Phosphatidylinositol 3- and 4-kinase
163	PSIP1	oncoprotein	6	0.467	3.494	AT_hook (PF02178, IPR017956, SM00384): AT hook motif BEX (PF04538, IPR021156): Brain expressed X-linked like family DUF1510 (PF07423, IPR009988): Protein of unknown function (DUF1510) PGA2 (PF07543, IPR011431): Protein trafficking PGA2 PWWP (PF00855, IPR000313, SM00293): PWWP domain LEDGF (PF11467, IPR021567): Lens epithelium-derived growth factor (LEDGF) TERB2 (PF15101, IPR028065): Telomere-associated protein TERB2
164	PSMC5	protein found in more fusions	15	0.407	29.701	AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA) Laminin_II (PF06009, IPR010307): Laminin Domain II RILP (PF11461, IPR021563): Rab interacting lysosomal protein AAA_16 (PF13191): AAA ATPase domain
165	PTPA	suppressor	5	0.400	2.486	PTPA (PF03095, IPR004327): Phosphotyrosyl phosphate activator (PTPA) protein
166	PURA	interactor	3	1.000	0	PurA (PF04845, IPR006628, SM00712): PurA ssDNA and RNA-binding protein DUF3276 (PF11680, IPR021694): Protein of unknown function (DUF3276) FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
167	RAD51	interactor	12	0.400	16.314	Rad51 (PF08423, IPR013632): Rad51 HHH_5 (PF14520): Helix-hairpin-helix domain
168	RARA	oncoprotein	22	0.448	31.265	zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
169	RB1	suppressor	50	0.244	456.721	RB_A (PF01858, IPR002720): Retinoblastoma-associated protein A domain RB_B (PF01857, IPR002719): Retinoblastoma-associated protein B domain Rb_C (PF08934, IPR015030): Rb C-terminal domain DUF3452 (PF11934, IPR024599): Domain of unknown function (DUF3452) DUF4592 (PF15262, IPR028030): Domain of unknown function (DUF4592)
170	RBBP4	oncoprotein	25	0.427	68.025	eIF2A (PF08662, IPR013979): Eukaryotic translation initiation factor eIF2A WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Capsid_NCLDV (PF04451, IPR007542): Large eukaryotic DNA virus major capsid protein CAF1C_H4-bd (PF12265, IPR022052): Histone-binding protein RBBP4 or subunit C of CAF1 complex
171	RBBP7	suppressor	16	0.575	16.663	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Capsid_NCLDV (PF04451, IPR007542): Large eukaryotic DNA virus major capsid protein CAF1C_H4-bd (PF12265, IPR022052): Histone-binding protein RBBP4 or subunit C of CAF1 complex
172	RBL1	suppressor	17	0.471	19.753	RB_A (PF01858, IPR002720): Retinoblastoma-associated protein A domain RB_B (PF01857, IPR002719): Retinoblastoma-associated protein B domain Rb_C (PF08934, IPR015030): Rb C-terminal domain DUF3452 (PF11934, IPR024599): Domain of unknown function (DUF3452)
173	REL	oncoprotein	14	0.429	22.489	RHD_DNA_bind (PF00554, IPR011539): Rel homology DNA-binding domain RHD_dimer (PF16179, IPR032397): Rel homology dimerisation domain
174	RELA	oncoprotein	51	0.293	371.803	DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region RHD_DNA_bind (PF00554, IPR011539): Rel homology DNA-binding domain RHD_dimer (PF16179, IPR032397): Rel homology dimerisation domain
175	REST	oncoprotein	13	0.397	15.288	CENP-H (PF05837, IPR008426): Centromere protein H (CENP-H) Presenilin (PF01080, IPR001108): Presenilin RNA_POL_M_15KD (PF02150, IPR001529): RNA polymerases M/15 Kd subunit zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type DNA_RNApol_7kD (PF03604, IPR006591, SM00659): DNA directed RNA polymerase, 7 kDa subunit zf-C2H2_jaz (PF12171, IPR022755): Zinc-finger double-stranded RNA-binding zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_4 (PF13894): C2H2-type zinc finger zf-H2C2_5 (PF13909): C2H2-type zinc-finger domain SLBP_RNA_bind (PF15247, IPR029344): Histone RNA hairpin-binding protein RNA-binding domain
176	RNF4	interactor	9	0.429	5.229	Sgf11 (PF08209, IPR013246): Sgf11 (transcriptional regulation protein) zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain zf-UDP (PF14569, IPR027934): Zinc-binding RING-finger
177	RSF1	oncoprotein	2	1.000	0	DDT (PF02791, IPR004022, SM00571): DDT domain DTHCT (PF08070, IPR012542): DTHCT (NUC029) region DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777) PHD (PF00628, IPR019787, SM00249): PHD-finger UPF0239 (PF06783, IPR009621): Uncharacterised protein family (UPF0239) TFIIE-A_C (PF11521, IPR021600): C-terminal general transcription factor TFIIE alpha Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal WHIM1 (PF15612, IPR028942): WSTF, HB1, Itc1p, MBD9 motif 1
178	RXRA	oncoprotein	23	0.437	39.072	zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor Nuc_recep-AF1 (PF11825, IPR021780): Nuclear/hormone receptor activator site AF-1
179	SENP3	interactor	13	0.487	17.831	Nop53 (PF07767, IPR011687): Nop53 (60S ribosomal biogenesis) Peptidase_C48 (PF02902, IPR003653): Ulp1 protease family, C-terminal catalytic domain
180	SENP6	interactor	1	0	0	Peptidase_C48 (PF02902, IPR003653): Ulp1 protease family, C-terminal catalytic domain
181	SFPQ	oncoprotein	14	0.436	15.223	GRP (PF07172, IPR010800): Glycine rich protein family Herpes_PAP (PF03325, IPR004997): Herpesvirus polymerase accessory protein NOPS (PF08075, IPR012975): NOPS (NUC059) domain RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit PAT1 (PF09770, IPR019167): Topoisomerase II-associated protein PAT1 CYSTM (PF12734, IPR028144): Cysteine-rich TM module stress tolerance
182	SIN3A	oncoprotein	32	0.319	162.259	Sin3_corepress (PF08295, IPR013194, SM00761): Sin3 family co-repressor PAH (PF02671, IPR003822, SM00309): Paired amphipathic helix repeat Sin3a_C (PF16879, IPR031693): C-terminal domain of Sin3a protein
183	SKP2	suppressor	23	0.399	57.338	LRR_1 (PF00560, IPR001611): Leucine Rich Repeat LRR_2 (PF07723, IPR013101): Leucine Rich Repeat LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies) F-box-like (PF12937, IPR001810): F-box-like LRR_6 (PF13516, IPR001611): Leucine Rich repeat LRR_8 (PF13855, IPR001611): Leucine rich repeat
184	SMAD2	suppressor	29	0.413	93.250	MH1 (PF03165, IPR003619, SM00523): MH1 domain MH2 (PF03166, IPR001132, SM00524): MH2 domain
185	SMAD3	oncoprotein	47	0.314	301.143	MH1 (PF03165, IPR003619, SM00523): MH1 domain MH2 (PF03166, IPR001132, SM00524): MH2 domain
186	SMAD4	suppressor	23	0.459	43.625	MH1 (PF03165, IPR003619, SM00523): MH1 domain MH2 (PF03166, IPR001132, SM00524): MH2 domain
187	SMARCA4	suppressor	40	0.369	173.102	DUF1840 (PF08895, IPR014991): Domain of unknown function (DUF1840) HSA (PF07529, IPR014012, SM00573): HSA QLQ (PF08880, IPR014978, SM00951): QLQ SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain BRK (PF07533, IPR006576, SM00592): BRK domain Bromodomain (PF00439, IPR001487, SM00297): Bromodomain Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal DUF4065 (PF13274, IPR025272): Protein of unknown function (DUF4065) SnAC (PF14619, IPR029295): Snf2-ATP coupling, chromatin remodelling complex WRNPLPNID (PF15017): Putative WW-binding domain and destruction box
188	SMARCC1	suppressor	18	0.618	11.203	SWIRM (PF04433, IPR007526): SWIRM domain Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain DUF2618 (PF10940, IPR021237): Protein of unknown function (DUF2618) PTPRCAP (PF15713, IPR016553): Protein tyrosine phosphatase receptor type C-associated SWIRM-assoc_1 (PF16495, IPR032451): SWIRM-associated region 1 SWIRM-assoc_2 (PF16496, IPR032450): SWIRM-associated domain at the N-terminal SWIRM-assoc_3 (PF16498, IPR032448): SWIRM-associated domain at the C-terminal
189	SMARCC2	interactor	17	0.507	21.841	GHMP_kinases_N (PF00288, IPR006204): GHMP kinases N terminal domain SWIRM (PF04433, IPR007526): SWIRM domain DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360) Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain SWIRM-assoc_1 (PF16495, IPR032451): SWIRM-associated region 1 SWIRM-assoc_2 (PF16496, IPR032450): SWIRM-associated domain at the N-terminal SWIRM-assoc_3 (PF16498, IPR032448): SWIRM-associated domain at the C-terminal
190	SP3	interactor	23	0.344	97.163	K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
191	SP4	interactor	6	0.533	3.748	zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360) Macoilin (PF09726, IPR019130): Transmembrane protein PAT1 (PF09770, IPR019167): Topoisomerase II-associated protein PAT1 DUF3446 (PF11928, IPR021849): Domain of unknown function (DUF3446) zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_4 (PF13894): C2H2-type zinc finger SEEEED (PF14797, IPR029394): Serine-rich region of AP3B1, clathrin-adaptor complex
192	SREBF1	interactor	12	0.564	7.470	HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain GIT_CC (PF16559, IPR032352): GIT coiled-coil Rho guanine nucleotide exchange factor
193	SREBF2	protein found in more fusions	16	0.400	34.163	HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
194	SRF	interactor	21	0.347	66.617	SRF-TF (PF00319, IPR002100, SM00432): SRF-type transcription factor (DNA-binding and dimerisation domain)
195	SRRT	interactor	5	0.400	2.202	ARS2 (PF04959, IPR007042): Arsenite-resistance protein 2 DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777) RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TRAP_alpha (PF03896, IPR005595): Translocon-associated protein (TRAP), alpha subunit Macoilin (PF09726, IPR019130): Transmembrane protein DUF3546 (PF12066, IPR021933): Domain of unknown function (DUF3546) DUF4187 (PF13821, IPR025239): Domain of unknown function (DUF4187)
196	SRY	interactor	5	0.900	0.100	DUF1908 (PF08926, IPR015022): Domain of unknown function (DUF1908) HMG_box (PF00505, IPR009071, SM00398): HMG (high mobility group) box
197	STAT3	suppressor	33	0.345	152.973	SH2 (PF00017, IPR000980, SM00252): SH2 domain STAT_alpha (PF01017, IPR013800): STAT protein, all-alpha domain STAT_bind (PF02864, IPR013801): STAT protein, DNA binding domain STAT_int (PF02865, IPR013799, SM00964): STAT protein, protein interaction domain
198	STRAP	protein found in more fusions	7	0.733	0.787	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
199	SUB1	interactor	9	0.321	11.745	Dehydrin (PF00257, IPR000167): Dehydrin PC4 (PF02229, IPR003173): Transcriptional Coactivator p15 (PC4)
200	SYK	suppressor	8	0.524	2.392	Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain
201	TAF4	protein found in more fusions	8	0.476	4.458	TAF4 (PF05236, IPR007900): Transcription initiation factor TFIID component TAF4 family TAFH (PF07531, IPR003894, SM00549): NHR1 homology to TAF TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit DUF3729 (PF12526, IPR022202): Protein of unknown function (DUF3729)
202	TAL1	oncoprotein	14	0.449	17.808	HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain SelK_SelG (PF10961, IPR024491): Selenoprotein SelK_SelG
203	TBP	interactor	31	0.301	145.481	TBP (PF00352, IPR000814): Transcription factor TFIID (or TATA-binding protein, TBP) EPL1 (PF10513, IPR019542): Enhancer of polycomb-like Med3 (PF11593, IPR020998): Mediator complex subunit 3 fungal
204	TBX21	oncoprotein	5	0.500	2.586	T-box (PF00907, IPR001699, SM00425): T-box T-box_assoc (PF16176, IPR032385): T-box transcription factor-associated
205	TFAP2A	suppressor	14	0.637	5.446	TF_AP-2 (PF03299, IPR013854): Transcription factor AP-2 CYYR1 (PF10873, IPR022640): Cysteine and tyrosine-rich protein 1 Peptidase_Prp (PF04327): Cysteine protease Prp
206	TFAP4	oncoprotein	13	0.423	24.213	DivIC (PF04977, IPR007060): Septum formation initiator HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain DUF2407 (PF10302, IPR019413): DUF2407 ubiquitin-like domain
207	TIMELESS	interactor	1	0	0	Myc_N (PF01056, IPR012682): Myc amino-terminal region TIMELESS (PF04821, IPR006906): Timeless protein TIMELESS_C (PF05029, IPR007725): Timeless protein C terminal region Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
208	TLX3	oncoprotein	2	1.000	0	Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
209	TNFRSF11A	oncoprotein	2	1.000	0	Abi (PF02517, IPR003675): CAAX protease self-immunity DAG1 (PF05454, IPR008465): Dystroglycan (Dystrophin-associated glycoprotein 1) KIX (PF02172, IPR003101): KIX domain TNFR_c6 (PF00020, IPR001368, SM00208): TNFR/NGFR cysteine-rich region
210	TP53	suppressor	79	0.193	1257.822	DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region P53 (PF00870, IPR011615): P53 DNA-binding domain P53_tetramer (PF07710, IPR010991): P53 tetramerisation motif
211	TPI1	interactor	3	1.000	0	TIM (PF00121, IPR000652): Triosephosphate isomerase
212	TPM1	protein found in more fusions	14	0.474	26.956	Tropomyosin (PF00261, IPR000533): Tropomyosin Tropomyosin_1 (PF12718, IPR000533): Tropomyosin like
213	TPM2	protein found in more fusions	12	0.455	17.071	DASH_Spc19 (PF08287, IPR013251): Spc19 Tropomyosin (PF00261, IPR000533): Tropomyosin Tropomyosin_1 (PF12718, IPR000533): Tropomyosin like
214	TPM3	oncoprotein	12	0.618	10.702	Tropomyosin (PF00261, IPR000533): Tropomyosin Tropomyosin_1 (PF12718, IPR000533): Tropomyosin like
215	TPM4	oncoprotein	9	0.778	3.556	Tropomyosin (PF00261, IPR000533): Tropomyosin Tropomyosin_1 (PF12718, IPR000533): Tropomyosin like
216	TTN	interactor	5	0.400	1.737	DUF11 (PF01345, IPR001434): Domain of unknown function DUF11 fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region I-set (PF07679, IPR013098): Immunoglobulin I-set domain Pkinase (PF00069, IPR000719): Protein kinase domain PPAK (PF02818, IPR004168): PPAK motif Titin_Z (PF09042, IPR015129): Titin Z V-set (PF07686, IPR013106): Immunoglobulin V-set domain Y_Y_Y (PF07495, IPR011123): Y_Y_Y domain DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369) Ig_3 (PF13927): Immunoglobulin domain
217	TUBA1B	interactor	4	0.500	3.000	Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain
218	TUBB3	interactor	4	0.500	2.333	Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain
219	TUBB4A	interactor	2	1.000	0	Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain
220	USP39	oncoprotein	2	1.000	0	UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase zf-UBP (PF02148, IPR001607, SM00290): Zn-finger in ubiquitin-hydrolases and other protein
221	VHL	suppressor	29	0.339	95.222	Trypan_PARP (PF05887, IPR008882): Procyclic acidic repetitive protein (PARP) VHL (PF01847, IPR022772): von Hippel-Lindau disease tumour suppressor protein VHL_C (PF17211): VHL box domain
222	VIM	suppressor	12	0.345	21.354	Filament (PF00038, IPR001664): Intermediate filament protein Filament_head (PF04732, IPR006821): Intermediate filament head (DNA binding) region
223	YY1	protein found in more fusions	29	0.339	100.760	zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_4 (PF13894): C2H2-type zinc finger Keratin_2_tail (PF16210, IPR032449): Keratin type II cytoskeletal 1 tail
224	ZBTB2	interactor	5	1.000	0	BTB (PF00651, IPR013069, SM00225): BTB/POZ domain zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-met (PF12874): Zinc-finger of C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
225	ZBTB7A	interactor	17	0.500	18.885	BTB (PF00651, IPR013069, SM00225): BTB/POZ domain GAGA (PF09237, IPR015318): GAGA factor zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_4 (PF13894): C2H2-type zinc finger
226	ZBTB7B	interactor	9	0.607	3.497	BTB (PF00651, IPR013069, SM00225): BTB/POZ domain CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal GAGA (PF09237, IPR015318): GAGA factor SMN (PF06003, IPR010304): Survival motor neuron protein (SMN) zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain

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