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Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

Powered by Cytoscape Web for: parental proteins SOX13 (from a repository: Tue Dec 6 06:05:09 2016)
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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)7
The number (and %) of the onco-proteins1 (14.29 %)
The number (and %) of the tumor suppressors0 (0.00 %)
Total number of binary PPIs (saturation %)9 (42.86 %)
The number (and %) of affected PPIs7 (77.78 %)
The number of possible different fusions3
PPI diameter2
PPI radius1
The average degree of PPI2.000
Assortativity coefficient-0.4714
The network average Clustering coefficient0.295
The number (and %) of a zero Clustering coefficients4 (57.14 %)
The number (and %) of a zero Betweenness Centrality6 (85.71 %)

ACTIVE INTERACTORS


List of the fusions

PPI for parental proteins: SOX13 All fusions
: BG988450;
Proteins found in more fusions SOX13 (see 1 fusions); CTBP2 (see 2 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 SOX13parental protein70.06728.000FAP (PF07174, IPR010801): Fibronectin-attachment protein (FAP)
HMG_box (PF00505, IPR009071, SM00398): HMG (high mobility group) box
AAA_23 (PF13476): AAA domain
PBP_N (PF17093, IPR031375): Penicillin-binding protein N-terminus
2 CEP85interactor21.0000DUF16 (PF01519, IPR002862): Protein of unknown function DUF16
SlyX (PF04102, IPR007236): SlyX
Jnk-SapK_ap_N (PF09744, IPR019143): JNK_SAPK-associated protein-1
KLRAQ (PF10205, IPR019343): Predicted coiled-coil domain-containing protein
ADIP (PF11559, IPR021622): Afadin- and alpha -actinin-Binding
TMF_TATA_bd (PF12325, IPR022091): TATA element modulatory factor 1 TATA binding
3 CLEC12Ainteractor100Ly49 (PF08391, IPR013600): Ly49-like protein, N-terminal region
Lectin_C (PF00059, IPR001304, SM00034): Lectin C-type domain
4 CTBP2protein found in more fusions2002-Hacid_dh_C (PF02826, IPR006140): D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
5 SMAD7interactor100MH1 (PF03165, IPR003619, SM00523): MH1 domain
MH2 (PF03166, IPR001132, SM00524): MH2 domain
6 XPO1interactor21.0000CRM1_C (PF08767, IPR014877, SM01102): CRM1 C terminal
Hydrolase_3 (PF08282, IPR023214): haloacid dehalogenase-like hydrolase
IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain
Xpo1 (PF08389, IPR013598): Exportin 1-like protein
Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region
7 YTHDC1interactor100DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777)
Merozoite_SPAM (PF07133, IPR010784): Merozoite surface protein (SPAM)
Prothymosin (PF03247, IPR004931): Prothymosin/parathymosin family
YTH (PF04146, IPR007275): YT521-B-like domain
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
TFB6 (PF17110, IPR031349): Subunit 11 of the general transcription factor TFIIH

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