1 |
SNRNP200 | parental protein | 152 | 0.168 | 8533.671 | DEAD (PF00270, IPR011545): DEAD/DEAH box helicase DUF603 (PF04645, IPR006739): Protein of unknown function, DUF603 Sec63 (PF02889, IPR004179, SM00973): Sec63 Brl domain Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain |
2 |
AAR2 | interactor | 8 | 0.607 | 4.626 | AAR2 (PF05282, IPR007946): AAR2 protein |
3 |
APC | suppressor | 5 | 0.500 | 0.583 | APC_15aa (PF05972, IPR009240): APC 15 residue motif APC_basic (PF05956, IPR009234): APC basic domain APC_r (PF05923): APC repeat Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972) EB1_binding (PF05937, IPR009232): EB-1 Binding Domain FYDLN_acid (PF09538, IPR012644): Protein of unknown function (FYDLN_acid) SAMP (PF05924, IPR009224): SAMP Motif Suppressor_APC (PF11414, IPR026831): Adenomatous polyposis coli tumour suppressor protein AIF_C (PF14721, IPR029324): Apoptosis-inducing factor, mitochondrion-associated, C-term SAS4 (PF15460, IPR029184): Something about silencing, SAS, complex subunit 4 Arm_APC_u3 (PF16629): Armadillo-associated region on APC APC_u5 (PF16630): Unstructured region on APC between 1st and 2nd catenin-bdg motifs APC_u9 (PF16633): Unstructured region on APC between 1st two creatine-rich regions APC_u13 (PF16634): Unstructured region on APC between APC_crr and SAMP APC_u14 (PF16635): Unstructured region on APC between SAMP and APC_crr APC_u15 (PF16636): Unstructured region on APC between APC_crr regions 5 and 6 APC_N_CC (PF16689, IPR032038): Coiled-coil N-terminus of APC, dimerisation domain |
4 |
BARD1 | suppressor | 17 | 0.408 | 27.907 | BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_5 (PF13857): Ankyrin repeats (many copies) zf-RING_6 (PF14835): zf-RING of BARD1-type protein BRCT_2 (PF16589, IPR001357): BRCT domain, a BRCA1 C-terminus domain |
5 |
BCAS2 | interactor | 24 | 0.656 | 12.589 | BCAS2 (PF05700, IPR008409): Breast carcinoma amplified sequence 2 (BCAS2) ZapB (PF06005, IPR009252): Cell division protein ZapB |
6 |
BLM | suppressor | 15 | 0.418 | 9.011 | BDHCT (PF08072, IPR012532): BDHCT (NUC031) domain DEAD (PF00270, IPR011545): DEAD/DEAH box helicase HRDC (PF00570, IPR002121, SM00341): HRDC domain RQC (PF09382, IPR018982, SM00956): RQC domain Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain ALMT (PF11744, IPR020966): Aluminium activated malate transporter RecQ_Zn_bind (PF16124, IPR032284): RecQ zinc-binding BLM_N (PF16202, IPR032437): N-terminal region of Bloom syndrome protein BDHCT_assoc (PF16204, IPR032439): BDHCT-box associated domain on Bloom syndrome protein |
7 |
BPTF | interactor | 7 | 0.429 | 7.545 | Arc_PepC_II (PF06847, IPR009655): Archaeal Peptidase A24 C-terminus Type II CobT (PF06213, IPR006538): Cobalamin biosynthesis protein CobT DDT (PF02791, IPR004022, SM00571): DDT domain DUF1764 (PF08576, IPR013885): Eukaryotic protein of unknown function (DUF1764) GRP (PF07172, IPR010800): Glycine rich protein family OAD_gamma (PF04277, IPR005899): Oxaloacetate decarboxylase, gamma chain PHD (PF00628, IPR019787, SM00249): PHD-finger SDA1 (PF05285, IPR007949): SDA1 Trypan_PARP (PF05887, IPR008882): Procyclic acidic repetitive protein (PARP) Bromodomain (PF00439, IPR001487, SM00297): Bromodomain WHIM1 (PF15612, IPR028942): WSTF, HB1, Itc1p, MBD9 motif 1 WSD (PF15613, IPR028941): Williams-Beuren syndrome DDT (WSD), D-TOX E motif CCSAP (PF15748, IPR029774): Centriole, cilia and spindle-associated PNISR (PF15996, IPR031937): Arginine/serine-rich protein PNISR |
8 |
BRCA1 | suppressor | 24 | 0.312 | 70.719 | BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger) BRCT_assoc (PF12820, IPR025994): Serine-rich domain associated with BRCT |
9 |
CAND1 | interactor | 55 | 0.432 | 189.075 | Adaptin_N (PF01602, IPR002553): Adaptin N terminal region DUF1981 (PF09324, IPR015403): Domain of unknown function (DUF1981) HEAT (PF02985, IPR000357): HEAT repeat TIP120 (PF08623, IPR013932): TATA-binding protein interacting (TIP20) RTP1_C1 (PF10363, IPR019451): Required for nuclear transport of RNA pol II C-terminus 1 DUF3385 (PF11865, IPR024585): Domain of unknown function (DUF3385) MMS19_C (PF12460, IPR024687): RNAPII transcription regulator C-terminal Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region HEAT_EZ (PF13513): HEAT-like repeat HEAT_2 (PF13646): HEAT repeats MMS19_N (PF14500): Dos2-interacting transcription regulator of RNA-Pol-II |
10 |
CCDC8 | interactor | 28 | 0.467 | 39.064 | Borrelia_P83 (PF05262, IPR007926): Borrelia P83/100 protein SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal PNMA (PF14893, IPR026523): PNMA |
11 |
CD2BP2 | interactor | 15 | 0.667 | 12.189 | GYF (PF02213, IPR003169, SM00444): GYF domain EF-1_beta_acid (PF10587, IPR018940): Eukaryotic elongation factor 1 beta central acidic region Hist_rich_Ca-bd (PF10529, IPR019552): Histidine-rich Calcium-binding repeat region |
12 |
CDC5L | interactor | 66 | 0.437 | 284.930 | OmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like) Pox_A_type_inc (PF04508, IPR007596): Viral A-type inclusion protein repeat Cir_N (PF10197, IPR019339, SM01083): N-terminal domain of CBF1 interacting co-repressor CIR Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain Myb_Cef (PF11831, IPR021786): pre-mRNA splicing factor component Myb_DNA-bind_6 (PF13921): Myb-like DNA-binding domain |
13 |
CDKN1A | suppressor | 7 | 0.714 | 1.832 | CDI (PF02234, IPR003175): Cyclin-dependent kinase inhibitor |
14 |
CHMP1B | interactor | 2 | 0 | 0 | Snf7 (PF03357, IPR005024): Snf7 |
15 |
COPS5 | protein found in more fusions | 44 | 0.474 | 110.137 | JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease |
16 |
CPT1A | interactor | 7 | 0.381 | 2.657 | Carn_acyltransf (PF00755, IPR000542): Choline/Carnitine o-acyltransferase CPT_N (PF16484, IPR032476): Carnitine O-palmitoyltransferase N-terminus |
17 |
CRNKL1 | interactor | 21 | 0.581 | 19.332 | NRDE-2 (PF08424, IPR013633): NRDE-2, necessary for RNA interference HAT (PF02184, IPR003107, SM00386): HAT (Half-A-TPR) repeat Mad3_BUB1_I (PF08311, IPR013212, SM00777): Mad3/BUB1 homology region 1 Suf (PF05843, IPR008847): Suppressor of forked protein (Suf) U3_assoc_6 (PF08640, IPR013949): U3 small nucleolar RNA-associated protein 6 TPR_14 (PF13428): Tetratricopeptide repeat TPR_16 (PF13432): Tetratricopeptide repeat |
18 |
CRY2 | protein found in more fusions | 13 | 0.439 | 8.496 | DNA_photolyase (PF00875, IPR006050): DNA photolyase FAD_binding_7 (PF03441, IPR005101): FAD binding domain of DNA photolyase |
19 |
CUL2 | suppressor | 29 | 0.564 | 24.982 | Cullin (PF00888, IPR001373, SM00182): Cullin family Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain |
20 |
CUL3 | protein found in more fusions | 67 | 0.386 | 384.047 | Cullin (PF00888, IPR001373, SM00182): Cullin family Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain WAC_Acf1_DNA_bd (PF10537, IPR013136): ATP-utilising chromatin assembly and remodelling N-terminal |
21 |
CUL5 | suppressor | 26 | 0.597 | 20.289 | Cullin (PF00888, IPR001373, SM00182): Cullin family GlutR_dimer (PF00745, IPR015896): Glutamyl-tRNAGlu reductase, dimerisation domain Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain |
22 |
CUL7 | protein found in more fusions | 52 | 0.456 | 142.949 | ANAPC10 (PF03256, IPR004939): Anaphase-promoting complex, subunit 10 (APC10) Cullin (PF00888, IPR001373, SM00182): Cullin family DUF1918 (PF08940, IPR015035): Domain of unknown function (DUF1918) Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain Cul7 (PF11515, IPR021097): Mouse development and cellular proliferation protein Cullin-7 |
23 |
DCUN1D1 | interactor | 18 | 0.739 | 5.988 | Cullin_binding (PF03556, IPR005176): Cullin binding UBA_4 (PF14555): UBA-like domain |
24 |
DDX23 | interactor | 39 | 0.393 | 135.844 | DEAD (PF00270, IPR011545): DEAD/DEAH box helicase FUSC (PF04632, IPR006726): Fusaric acid resistance protein family Transformer (PF06495, IPR010519): Fruit fly transformer protein Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain DUF3698 (PF12479, IPR022167): Protein of unknown function (DUF3698) PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term |
25 |
DHX15 | interactor | 54 | 0.412 | 173.939 | DEAD (PF00270, IPR011545): DEAD/DEAH box helicase OB_NTP_bind (PF07717, IPR011709): Oligonucleotide/oligosaccharide-binding (OB)-fold DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777) HA2 (PF04408, IPR007502, SM00847): Helicase associated domain (HA2) Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain AAA_29 (PF13555): P-loop containing region of AAA domain |
26 |
EAPP | interactor | 6 | 0.600 | 1.242 | Serglycin (PF04360, IPR007455): Serglycin Eapp_C (PF10238, IPR019370): E2F-associated phosphoprotein |
27 |
ECT2 | suppressor | 8 | 0.464 | 6.711 | BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain PTCB-BRCT (PF12738, IPR001357): twin BRCT domain PGBA_C (PF15437, IPR032737): Plasminogen-binding protein pgbA C-terminal |
28 |
EED | suppressor | 40 | 0.493 | 112.413 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160 ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain |
29 |
EFTUD2 | interactor | 79 | 0.297 | 766.403 | EFG_C (PF00679, IPR000640, SM00838): Elongation factor G C-terminus EFG_IV (PF03764, IPR005517, SM00889): Elongation factor G, domain IV GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2 EFG_II (PF14492, IPR009022): Elongation Factor G, domain II EFTUD2 (PF16004, IPR031950): 116 kDa U5 small nuclear ribonucleoprotein component N-terminus |
30 |
EIF4A3 | interactor | 52 | 0.523 | 91.806 | DEAD (PF00270, IPR011545): DEAD/DEAH box helicase Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain |
31 |
ELP3 | interactor | 2 | 1.000 | 0 | Acetyltransf_1 (PF00583, IPR000182): Acetyltransferase (GNAT) family Radical_SAM (PF04055, IPR007197): Radical SAM superfamily Radical_SAM_C (PF16199, IPR032432): Radical_SAM C-terminal domain |
32 |
EMD | interactor | 18 | 0.346 | 20.608 | LEM (PF03020, IPR003887, SM00540): LEM domain SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein |
33 |
ERG | oncoprotein | 15 | 0.543 | 7.313 | Ets (PF00178, IPR000418, SM00413): Ets-domain SAM_2 (PF07647, IPR011510): SAM domain (Sterile alpha motif) SAM_PNT (PF02198, IPR003118, SM00251): Sterile alpha motif (SAM)/Pointed domain |
34 |
EZH2 | suppressor | 25 | 0.489 | 34.654 | CDC45 (PF02724, IPR003874): CDC45-like protein TCR (PF03638, IPR005172, SM01114): Tesmin/TSO1-like CXC domain, cysteine-rich domain SET (PF00856, IPR001214, SM00317): SET domain EZH2_WD-Binding (PF11616, IPR021654): WD repeat binding protein EZH2 Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal |
35 |
FBXO6 | interactor | 25 | 0.423 | 32.509 | FBA (PF04300, IPR007397): F-box associated region F-box-like (PF12937, IPR001810): F-box-like |
36 |
FERMT3 | interactor | 5 | 0.600 | 1.070 | FERM_M (PF00373, IPR019748): FERM central domain FERM_N (PF09379, IPR018979): FERM N-terminal domain |
37 |
FN1 | oncoprotein | 39 | 0.421 | 85.952 | fn1 (PF00039, IPR000083, SM00058): Fibronectin type I domain fn2 (PF00040, IPR000562, SM00059): Fibronectin type II domain fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369) |
38 |
FOXG1 | oncoprotein | 1 | 0 | 0 | SelP_N (PF04592, IPR007671): Selenoprotein P, N terminal region SPX (PF03105, IPR004331): SPX domain DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360) Forkhead (PF00250, IPR001766, SM00339): Forkhead domain |
39 |
FOXK2 | interactor | 7 | 0.333 | 10.919 | FHA (PF00498, IPR000253, SM00240): FHA domain Forkhead (PF00250, IPR001766, SM00339): Forkhead domain |
40 |
FOXM1 | oncoprotein | 6 | 0.600 | 2.265 | EspF (PF04806, IPR006891): EspF protein repeat Forkhead (PF00250, IPR001766, SM00339): Forkhead domain |
41 |
FOXQ1 | interactor | 8 | 0.536 | 5.363 | Forkhead (PF00250, IPR001766, SM00339): Forkhead domain |
42 |
GCFC2 | interactor | 5 | 0.900 | 0.105 | DUF1676 (PF07898, IPR012464): Protein of unknown function (DUF1676) GCFC (PF07842, IPR022783): GC-rich sequence DNA-binding factor-like protein |
43 |
GRB2 | oncoprotein | 18 | 0.500 | 26.964 | SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain DUF5093 (PF17011, IPR031533): Domain of unknown function (DUF5093) |
44 |
HDAC5 | protein found in more fusions | 29 | 0.497 | 50.549 | Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain NOA36 (PF06524, IPR010531): NOA36 protein Activator_LAG-3 (PF11498, IPR021587): Transcriptional activator LAG-3 HDAC4_Gln (PF12203, IPR024643): Glutamine rich N terminal domain of histone deacetylase 4 |
45 |
HNRNPA1 | interactor | 56 | 0.444 | 138.247 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HnRNPA1 (PF11627, IPR021662): Nuclear factor hnRNPA1 |
46 |
HNRNPC | protein found in more fusions | 50 | 0.373 | 176.149 | APG6 (PF04111, IPR007243): Autophagy protein Apg6 RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SURF2 (PF05477, IPR008833): Surfeit locus protein 2 (SURF2) |
47 |
HNRNPR | interactor | 53 | 0.481 | 140.549 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 (PF11608, IPR024582): Limkain b1 |
48 |
HNRNPU | interactor | 61 | 0.390 | 248.305 | CDC45 (PF02724, IPR003874): CDC45-like protein Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein SAP (PF02037, IPR003034, SM00513): SAP domain SPRY (PF00622, IPR003877, SM00449): SPRY domain AAA_33 (PF13671): AAA domain WRNPLPNID (PF15017): Putative WW-binding domain and destruction box |
49 |
HSP90AA1 | oncoprotein | 42 | 0.340 | 213.201 | HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HSP90 (PF00183, IPR001404): Hsp90 protein |
50 |
HSPB1 | oncoprotein | 34 | 0.441 | 72.446 | HSP20 (PF00011, IPR002068): Hsp20/alpha crystallin family |
51 |
HUWE1 | oncoprotein | 36 | 0.424 | 82.468 | BUD22 (PF09073, IPR015158): BUD22 DUF908 (PF06012, IPR010309): Domain of Unknown Function (DUF908) DUF913 (PF06025, IPR010314): Domain of Unknown Function (DUF913) FdhE (PF04216, IPR006452): Protein involved in formate dehydrogenase formation HABP4_PAI-RBP1 (PF04774, IPR006861): Hyaluronan / mRNA binding family Ku_C (PF03730, IPR005160): Ku70/Ku80 C-terminal arm Merozoite_SPAM (PF07133, IPR010784): Merozoite surface protein (SPAM) Mucin (PF01456, IPR000458): Mucin-like glycoprotein Nop14 (PF04147, IPR007276): Nop14-like family PBP_sp32 (PF07222, IPR009865): Proacrosin binding protein sp32 RNA_pol_Rpc4 (PF05132, IPR007811): RNA polymerase III RPC4 TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain WWE (PF02825, IPR004170, SM00678): WWE domain HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase) Tim54 (PF11711, IPR021056): Inner membrane protein import complex subunit Tim54 U1snRNP70_N (PF12220, IPR022023): U1 small nuclear ribonucleoprotein of 70kDa MW N terminal DUF4414 (PF14377, IPR025527): Domain of unknown function (DUF4414) |
52 |
IRAK1 | interactor | 11 | 0.489 | 12.141 | Death (PF00531, IPR000488, SM00005): Death domain Pkinase (PF00069, IPR000719): Protein kinase domain |
53 |
IRAK2 | oncoprotein | 5 | 0.800 | 1.333 | Death (PF00531, IPR000488, SM00005): Death domain Pkinase (PF00069, IPR000719): Protein kinase domain |
54 |
ISG15 | suppressor | 7 | 0.619 | 1.148 | ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family |
55 |
ITGA4 | interactor | 30 | 0.507 | 46.464 | FG-GAP (PF01839, IPR013517): FG-GAP repeat Integrin_alpha (PF00357, IPR018184): Integrin alpha cytoplasmic region Integrin_alpha2 (PF08441, IPR013649): Integrin alpha |
56 |
KIAA1033 | interactor | 7 | 0.667 | 4.815 | WASH-7_mid (PF14744, IPR028282): WASH complex subunit 7 WASH-7_N (PF14745, IPR028191): WASH complex subunit 7, N-terminal WASH-7_C (PF14746, IPR028283): WASH complex subunit 7, C-terminal |
57 |
KIAA1429 | interactor | 9 | 0.472 | 8.192 | Mpp10 (PF04006, IPR007151): Mpp10 protein Sigma70_ner (PF04546, IPR007631): Sigma-70, non-essential region INTS5_N (PF14837, IPR029445): Integrator complex subunit 5 N-terminus VIR_N (PF15912, IPR031801): Virilizer, N-terminal |
58 |
LGR4 | interactor | 11 | 0.400 | 7.763 | 7tm_1 (PF00001, IPR000276): 7 transmembrane receptor (rhodopsin family) LRR_1 (PF00560, IPR001611): Leucine Rich Repeat LRRNT (PF01462, IPR000372, SM00013): Leucine rich repeat N-terminal domain LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies) LRR_8 (PF13855, IPR001611): Leucine rich repeat |
59 |
LSM8 | interactor | 10 | 0.356 | 9.594 | LSM (PF01423, IPR001163): LSM domain |
60 |
LUC7L2 | protein found in more fusions | 32 | 0.538 | 33.580 | LUC7 (PF03194, IPR004882): LUC7 N_terminus Paramyxo_ncap (PF00973, IPR002021): Paramyxovirus nucleocapsid protein Methyltransf_32 (PF13679, IPR025714): Methyltransferase domain |
61 |
MAGOH | interactor | 36 | 0.517 | 51.737 | Mago_nashi (PF02792, IPR004023): Mago nashi protein |
62 |
MCC | suppressor | 1 | 0 | 0 | ERM (PF00769, IPR011259): Ezrin/radixin/moesin family IFP_35_N (PF07334, IPR009938): Interferon-induced 35 kDa protein (IFP 35) N-terminus K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain Mod_r (PF07200, IPR009851): Modifier of rudimentary (Mod(r)) protein Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein MCC-bdg_PDZ (PF10506, IPR019536): PDZ domain of MCC-2 bdg protein for Usher syndrome TMF_DNA_bd (PF12329, IPR022092): TATA element modulatory factor 1 DNA binding EF-hand_7 (PF13499, IPR011992): EF-hand domain pair FAM76 (PF16046, IPR032017): FAM76 protein |
63 |
MCM2 | oncoprotein | 39 | 0.425 | 89.246 | AAA_3 (PF07726, IPR011703): ATPase family associated with various cellular activities (AAA) MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family MCM2_N (PF12619, IPR008045): Mini-chromosome maintenance protein 2 MCM_N (PF14551, IPR027925): MCM N-terminal domain MCM_OB (PF17207): MCM OB domain |
64 |
MCM5 | oncoprotein | 32 | 0.472 | 56.369 | MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family MCM_N (PF14551, IPR027925): MCM N-terminal domain MCM_OB (PF17207): MCM OB domain |
65 |
MED12 | oncoprotein | 6 | 0.733 | 1.232 | Med12 (PF09497, IPR019035): Transcription mediator complex subunit Med12 Peptidase_S15 (PF02129, IPR000383): X-Pro dipeptidyl-peptidase (S15 family) DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360) Med19 (PF10278, IPR019403): Mediator of RNA pol II transcription subunit 19 DUF2877 (PF11392, IPR021530): Protein of unknown function (DUF2877) Med12-PQL (PF12144, IPR021989): Eukaryotic Mediator 12 catenin-binding domain Med12-LCEWAV (PF12145, IPR021990): Eukaryotic Mediator 12 subunit domain CYSTM (PF12734, IPR028144): Cysteine-rich TM module stress tolerance |
66 |
MEGF10 | interactor | 1 | 0 | 0 | DSL (PF01414, IPR001774, SM00051): Delta serrate ligand EGF_2 (PF07974, IPR013111): EGF-like domain Syndecan (PF01034, IPR027789): Syndecan domain Laminin_EGF (PF00053, IPR002049, SM00180): Laminin EGF domain hEGF (PF12661, IPR013032): Human growth factor-like EGF cEGF (PF12662, IPR026823): Complement Clr-like EGF-like |
67 |
MEPCE | interactor | 27 | 0.527 | 31.810 | Bin3 (PF06859, IPR010675): Bicoid-interacting protein 3 (Bin3) Methyltransf_23 (PF13489): Methyltransferase domain FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 DLEU7 (PF15760, IPR031510): Leukemia-associated protein 7 |
68 |
MYC | oncoprotein | 26 | 0.427 | 42.319 | HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain Myc-LZ (PF02344, IPR003327): Myc leucine zipper domain Myc_N (PF01056, IPR012682): Myc amino-terminal region |
69 |
NTRK1 | oncoprotein | 68 | 0.332 | 516.669 | I-set (PF07679, IPR013098): Immunoglobulin I-set domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase LRR_8 (PF13855, IPR001611): Leucine rich repeat TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain |
70 |
OBSL1 | protein found in more fusions | 55 | 0.451 | 133.827 | BiPBP_C (PF06832, IPR009647): Penicillin-Binding Protein C-terminus Family fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain Herpes_gE (PF02480, IPR003404): Alphaherpesvirus glycoprotein E I-set (PF07679, IPR013098): Immunoglobulin I-set domain V-set (PF07686, IPR013106): Immunoglobulin V-set domain Ig_3 (PF13927): Immunoglobulin domain Ig_4 (PF16680, IPR032052): T-cell surface glycoprotein CD3 delta chain Izumo-Ig (PF16706, IPR032699): Izumo-like Immunoglobulin domain |
71 |
PABPC1 | oncoprotein | 40 | 0.449 | 77.963 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP (PF00658, IPR002004, SM00517): Poly-adenylate binding protein, unique domain YflT (PF11181, IPR025889): Heat induced stress protein YflT |
72 |
PARK2 | suppressor | 17 | 0.417 | 17.228 | IBR (PF01485, IPR002867, SM00647): IBR domain, a half RING-finger domain ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family |
73 |
PDCD7 | interactor | 4 | 0.500 | 0.554 | PDCD7 (PF16021, IPR031974): Programmed cell death protein 7 |
74 |
PHF6 | suppressor | 8 | 0.821 | 0.338 | zf-HC5HC2H (PF13771): PHD-like zinc-binding domain YqfQ (PF14181, IPR025571): YqfQ-like protein |
75 |
PIN1 | suppressor | 16 | 0.608 | 12.113 | Rotamase (PF00639, IPR000297): PPIC-type PPIASE domain WW (PF00397, IPR001202, SM00456): WW domain |
76 |
POLR2H | interactor | 7 | 0.467 | 3.186 | RNA_pol_Rpb8 (PF03870, IPR005570, SM00658): RNA polymerase Rpb8 |
77 |
PRKAB1 | oncoprotein | 3 | 0.667 | 0.333 | AMPKBI (PF04739, IPR006828, SM01010): 5'-AMP-activated protein kinase beta subunit, interaction domain AMPK1_CBM (PF16561, IPR032640): Glycogen recognition site of AMP-activated protein kinase |
78 |
PRPF19 | protein found in more fusions | 55 | 0.497 | 132.570 | Prp19 (PF08606, IPR013915): Prp19/Pso4-like WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat U-box (PF04564, IPR003613, SM00504): U-box domain ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain |
79 |
PRPF31 | interactor | 32 | 0.587 | 36.943 | Nop (PF01798, IPR002687): snoRNA binding domain, fibrillarin Cytokin_check_N (PF10407, IPR018844): Cdc14 phosphatase binding protein N-terminus Prp31_C (PF09785, IPR019175): Prp31 C terminal domain |
80 |
PRPF4 | interactor | 34 | 0.581 | 46.699 | PRP4 (PF08799, IPR014906): pre-mRNA processing factor 4 (PRP4) like WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain WD40_like (PF17005, IPR031544): WD40-like domain |
81 |
PRPF4B | oncoprotein | 23 | 0.585 | 15.110 | Afi1 (PF07792, IPR012860): Docking domain of Afi1 for Arf3 in vesicle trafficking Ureide_permease (PF07168, IPR009834): Ureide permease Pkinase (PF00069, IPR000719): Protein kinase domain Eapp_C (PF10238, IPR019370): E2F-associated phosphoprotein PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 SWIRM-assoc_2 (PF16496, IPR032450): SWIRM-associated domain at the N-terminal |
82 |
PRPF6 | protein found in more fusions | 45 | 0.446 | 144.154 | PRP1_N (PF06424, IPR010491): PRP1 splicing factor, N-terminal Suf (PF05843, IPR008847): Suppressor of forked protein (Suf) TPR_14 (PF13428): Tetratricopeptide repeat TPR_19 (PF14559): Tetratricopeptide repeat |
83 |
PRPF8 | oncoprotein | 85 | 0.311 | 799.842 | PRO8NT (PF08082, IPR012591): PRO8NT (NUC069), PrP8 N-terminal domain PROCN (PF08083, IPR012592): PROCN (NUC071) domain PROCT (PF08084, IPR012984): PROCT (NUC072) domain RRM_4 (PF10598, IPR019582): RNA recognition motif of the spliceosomal PrP8 U5_2-snRNA_bdg (PF10597, IPR019581): U5-snRNA binding site 2 of PrP8 U6-snRNA_bdg (PF10596, IPR019580): U6-snRNA interacting domain of PrP8 JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease PRP8_domainIV (PF12134, IPR021983): PRP8 domain IV core |
84 |
PSMC2 | protein found in more fusions | 16 | 0.467 | 12.142 | AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA) |
85 |
RAB4B | oncoprotein | 2 | 1.000 | 0 | Ras (PF00071, IPR001806, SM00173): Ras family |
86 |
RANBP2 | oncoprotein | 27 | 0.348 | 72.248 | Pro_isomerase (PF00160, IPR002130): Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat Ran_BP1 (PF00638, IPR000156, SM00160): RanBP1 domain zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others DUF2693 (PF10902, IPR024401): Protein of unknown function (DUF2693) IR1-M (PF12185, IPR022011): Nup358/RanBP2 E3 ligase domain Dmrt1 (PF12374, IPR022114): Double-sex mab3 related transcription factor 1 TPR_9 (PF13371, IPR011990): Tetratricopeptide repeat TPR_11 (PF13414, IPR011990): TPR repeat TPR_12 (PF13424): Tetratricopeptide repeat TPR_19 (PF14559): Tetratricopeptide repeat |
87 |
RBM39 | oncoprotein | 40 | 0.495 | 81.484 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MIP-T3 (PF10243): Microtubule-binding protein MIP-T3 RBM39linker (PF15519, IPR029123): linker between RRM2 and RRM3 domains in RBM39 protein |
88 |
RBM5 | suppressor | 10 | 0.644 | 3.489 | DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777) G-patch (PF01585, IPR000467, SM00443): G-patch domain RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others GSIII_N (PF12437, IPR022147): Glutamine synthetase type III N terminal PHM7_cyt (PF14703, IPR027815): Cytosolic domain of 10TM putative phosphate transporter zf-C2HE (PF16278, IPR032566): C2HE / C2H2 / C2HC zinc-binding finger |
89 |
RNF113A | interactor | 3 | 0.667 | 0.080 | zf-CCCH (PF00642, IPR000571): Zinc finger C-x8-C-x5-C-x3-H type (and similar) Pannexin_like (PF12534, IPR021040): Pannexin-like TM region of LRRC8 zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger) |
90 |
RNF2 | interactor | 49 | 0.410 | 201.070 | zf-C4_Topoisom (PF01396, IPR013498): Topoisomerase DNA binding C4 zinc finger zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger) RAWUL (PF16207, IPR032443): RAWUL domain RING finger- and WD40-associated ubiquitin-like |
91 |
RNPS1 | interactor | 34 | 0.560 | 38.472 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2457 (PF10446, IPR018853): Protein of unknown function (DUF2457) Macoilin (PF09726, IPR019130): Transmembrane protein |
92 |
RNU11 | interactor | 13 | 0.654 | 7.184 | NA |
93 |
RNU12 | interactor | 13 | 0.654 | 7.184 | NA |
94 |
RNU4ATAC | interactor | 8 | 1.000 | 0 | NA |
95 |
RNU6ATAC | interactor | 8 | 1.000 | 0 | NA |
96 |
RPA1 | suppressor | 41 | 0.445 | 99.103 | Rep-A_N (PF04057, IPR007199): Replication factor-A protein 1, N-terminal domain Rep_fac-A_C (PF08646, IPR013955): Replication factor-A C terminal domain tRNA_anti-codon (PF01336, IPR004365): OB-fold nucleic acid binding domain REPA_OB_2 (PF16900, IPR031657): Replication protein A OB domain |
97 |
RPA2 | oncoprotein | 37 | 0.416 | 104.238 | RPA_C (PF08784, IPR014892): Replication protein A C terminal tRNA_anti-codon (PF01336, IPR004365): OB-fold nucleic acid binding domain RMI2 (PF16100, IPR032245): RecQ-mediated genome instability protein 2 |
98 |
RPA3 | interactor | 35 | 0.417 | 88.872 | Rep_fac-A_3 (PF08661, IPR013970): Replication factor A protein 3 |
99 |
SART1 | interactor | 49 | 0.501 | 137.895 | SART-1 (PF03343, IPR005011): SART-1 family Dsh_C (PF12316, IPR024580): Segment polarity protein dishevelled (Dsh) C terminal |
100 |
SF3A1 | interactor | 48 | 0.524 | 91.269 | TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit Surp (PF01805, IPR000061, SM00648): Surp module ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family PRP21_like_P (PF12230, IPR022030): Pre-mRNA splicing factor PRP21 like protein |
101 |
SF3A2 | interactor | 44 | 0.518 | 93.175 | Cytadhesin_P30 (PF07271, IPR009896): Cytadhesin P30/P32 PRP4 (PF08799, IPR014906): pre-mRNA processing factor 4 (PRP4) like Totivirus_coat (PF05518, IPR008871): Totivirus coat protein zf-met (PF12874): Zinc-finger of C2H2 type ARL6IP6 (PF15062, IPR029383): Haemopoietic lineage transmembrane helix SF3A2 (PF16835, IPR031781): Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) |
102 |
SF3A3 | interactor | 40 | 0.499 | 82.822 | DUF3449 (PF11931, IPR024598): Domain of unknown function (DUF3449) SF3a60_bindingd (PF12108, IPR021966): Splicing factor SF3a60 binding domain Telomere_Sde2_2 (PF13297): Telomere stability C-terminal PBP1_TM (PF14812, IPR032730): Transmembrane domain of transglycosylase PBP1 at N-terminal SF3A3 (PF16837, IPR031774): Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 |
103 |
SF3B1 | oncoprotein | 63 | 0.412 | 283.590 | Dopey_N (PF04118, IPR007249): Dopey, N-terminal HEAT (PF02985, IPR000357): HEAT repeat SF3b1 (PF08920, IPR015016): Splicing factor 3B subunit 1 UNC45-central (PF11701, IPR024660): Myosin-binding striated muscle assembly central Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region HEAT_EZ (PF13513): HEAT-like repeat HEAT_2 (PF13646): HEAT repeats |
104 |
SF3B2 | interactor | 44 | 0.389 | 160.853 | DUF382 (PF04037, IPR007180): Domain of unknown function (DUF382) PAPA-1 (PF04795, IPR006880): PAPA-1-like conserved region PSP (PF04046, IPR006568, SM00581): PSP SAP (PF02037, IPR003034, SM00513): SAP domain Usp (PF00582, IPR006016): Universal stress protein family Med19 (PF10278, IPR019403): Mediator of RNA pol II transcription subunit 19 Vma12 (PF11712, IPR021013): Endoplasmic reticulum-based factor for assembly of V-ATPase FAM176 (PF14851): FAM176 family WRNPLPNID (PF15017): Putative WW-binding domain and destruction box |
105 |
SF3B3 | interactor | 64 | 0.431 | 238.005 | CPSF_A (PF03178, IPR004871): CPSF A subunit region MMS1_N (PF10433): Mono-functional DNA-alkylating methyl methanesulfonate N-term |
106 |
SIRT6 | suppressor | 5 | 0.700 | 1.202 | SIR2 (PF02146, IPR003000): Sir2 family TPP_enzyme_M (PF00205, IPR012000): Thiamine pyrophosphate enzyme, central domain |
107 |
SIRT7 | interactor | 34 | 0.307 | 141.073 | DUF563 (PF04577, IPR007657): Protein of unknown function (DUF563) SIR2 (PF02146, IPR003000): Sir2 family |
108 |
SMNDC1 | interactor | 7 | 0.905 | 0.171 | SMN (PF06003, IPR010304): Survival motor neuron protein (SMN) |
109 |
SNCA | interactor | 15 | 0.363 | 25.014 | Synuclein (PF01387, IPR001058): Synuclein |
110 |
SNRNP40 | interactor | 32 | 0.494 | 62.303 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat |
111 |
SNRNP70 | interactor | 42 | 0.502 | 70.351 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MIP-T3 (PF10243): Microtubule-binding protein MIP-T3 U1snRNP70_N (PF12220, IPR022023): U1 small nuclear ribonucleoprotein of 70kDa MW N terminal |
112 |
SNRPA1 | interactor | 43 | 0.543 | 72.633 | LRR_9 (PF14580): Leucine-rich repeat |
113 |
SNRPB | interactor | 32 | 0.419 | 63.493 | LSM (PF01423, IPR001163): LSM domain |
114 |
SNRPB2 | interactor | 23 | 0.561 | 14.855 | DUF1027 (PF06265, IPR009370): Protein of unknown function (DUF1027) RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
115 |
SNRPD1 | interactor | 52 | 0.478 | 128.810 | API5 (PF05918, IPR008383): Apoptosis inhibitory protein 5 (API5) LSM (PF01423, IPR001163): LSM domain |
116 |
SNRPD2 | interactor | 51 | 0.450 | 136.459 | LSM (PF01423, IPR001163): LSM domain |
117 |
SNRPD3 | interactor | 46 | 0.510 | 76.911 | LSM (PF01423, IPR001163): LSM domain |
118 |
SNRPE | interactor | 23 | 0.621 | 16.310 | LSM (PF01423, IPR001163): LSM domain |
119 |
SNW1 | protein found in more fusions | 59 | 0.475 | 153.547 | SKIP_SNW (PF02731, IPR004015): SKIP/SNW domain PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term SIR4_SID (PF16991, IPR031556): Sir4 SID domain |
120 |
SRRM1 | interactor | 35 | 0.499 | 70.641 | DUF1754 (PF08555, IPR013865): Eukaryotic family of unknown function (DUF1754) ETRAMP (PF09716, IPR006389): Malarial early transcribed membrane protein (ETRAMP) Hepatitis_core (PF00906, IPR002006): Hepatitis core antigen MAP65_ASE1 (PF03999, IPR007145): Microtubule associated protein (MAP65/ASE1 family) PWI (PF01480, IPR002483, SM00311): PWI domain Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein |
121 |
SRRM2 | interactor | 46 | 0.548 | 85.461 | cwf21 (PF08312, IPR013170, SM01115): cwf21 domain DUF1754 (PF08555, IPR013865): Eukaryotic family of unknown function (DUF1754) Pap_E4 (PF02711, IPR003861): E4 protein RR_TM4-6 (PF06459, IPR009460): Ryanodine Receptor TM 4-6 CTD (PF12815, IPR024945, SM01104): Spt5 C-terminal nonapeptide repeat binding Spt4 DUF4614 (PF15391, IPR027884): Domain of unknown function (DUF4614) |
122 |
SRSF1 | protein found in more fusions | 49 | 0.480 | 120.730 | Corona_nucleoca (PF00937, IPR001218): Coronavirus nucleocapsid protein RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 |
123 |
STAU1 | protein found in more fusions | 27 | 0.625 | 13.295 | dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif Staufen_C (PF16482, IPR032478): Staufen C-terminal domain |
124 |
SUZ12 | suppressor | 39 | 0.492 | 77.793 | DUF2070 (PF09843, IPR019204): Predicted membrane protein (DUF2070) VEFS-Box (PF09733, IPR019135): VEFS-Box of polycomb protein |
125 |
TARDBP | interactor | 42 | 0.467 | 105.085 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
126 |
TCEA1 | oncoprotein | 7 | 0.619 | 0.877 | Med26 (PF08711, IPR017923): TFIIS helical bundle-like domain TFIIS_C (PF01096, IPR001222): Transcription factor S-II (TFIIS) TFIIS_M (PF07500, IPR003618): Transcription factor S-II (TFIIS), central domain |
127 |
TFAP4 | oncoprotein | 5 | 0.500 | 4.333 | DivIC (PF04977, IPR007060): Septum formation initiator HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain DUF2407 (PF10302, IPR019413): DUF2407 ubiquitin-like domain |
128 |
THOC6 | interactor | 10 | 0.533 | 2.388 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 (PF16529, IPR032401): WD40 region of Ge1, enhancer of mRNA-decapping protein |
129 |
TIRAP | interactor | 4 | 1.000 | 0 | TIR_2 (PF13676, IPR000157): TIR domain |
130 |
TOP1 | oncoprotein | 36 | 0.538 | 49.452 | DUF1764 (PF08576, IPR013885): Eukaryotic protein of unknown function (DUF1764) Topoisom_I (PF01028, IPR013500): Eukaryotic DNA topoisomerase I, catalytic core Topoisom_I_N (PF02919, IPR008336): Eukaryotic DNA topoisomerase I, DNA binding fragment MCM_bind (PF09739, IPR019140): Mini-chromosome maintenance replisome factor Sox_N (PF12444, IPR022151): Sox developmental protein N terminal Topo_C_assoc (PF14370, IPR025834): C-terminal topoisomerase domain DUF4614 (PF15391, IPR027884): Domain of unknown function (DUF4614) TonB_N (PF16031): TonB N-terminal region |
131 |
TOP2B | oncoprotein | 15 | 0.419 | 11.546 | CENP-B_dimeris (PF09026, IPR015115): Centromere protein B dimerisation domain DASH_Spc19 (PF08287, IPR013251): Spc19 DNA_gyraseB (PF00204, IPR013506): DNA gyrase B DTHCT (PF08070, IPR012542): DTHCT (NUC029) region HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim (PF01751, IPR006171, SM00493): Toprim domain Anophelin (PF10731, IPR018932): Thrombin inhibitor from mosquito DNA_topoisoIV (PF00521, IPR002205, SM00434): DNA gyrase/topoisomerase IV, subunit A PBP1_TM (PF14812, IPR032730): Transmembrane domain of transglycosylase PBP1 at N-terminal TOPRIM_C (PF16898, IPR031660): C-terminal associated domain of TOPRIM |
132 |
TSC22D1 | suppressor | 4 | 0.667 | 0.118 | SelP_N (PF04592, IPR007671): Selenoprotein P, N terminal region TSC22 (PF01166, IPR000580): TSC-22/dip/bun family ANAPC_CDC26 (PF10471, IPR018860): Anaphase-promoting complex APC subunit CDC26 SUIM_assoc (PF16619): Unstructured region C-term to UIM in Ataxin3 |
133 |
TSSC4 | suppressor | 14 | 0.593 | 10.534 | TSSC4 (PF15264, IPR029338): Tumour suppressing sub-chromosomal transferable candidate 4 |
134 |
TUBA1B | interactor | 16 | 0.442 | 13.604 | Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain |
135 |
TUBB | interactor | 38 | 0.343 | 123.550 | Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain |
136 |
U2AF2 | protein found in more fusions | 55 | 0.502 | 139.362 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Transformer (PF06495, IPR010519): Fruit fly transformer protein |
137 |
UBE2I | interactor | 19 | 0.405 | 28.042 | UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme |
138 |
UBR4 | interactor | 11 | 0.418 | 17.610 | CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal Pheromone (PF08015, IPR012597): Fungal mating-type pheromone RecR (PF02132, IPR023628): RecR protein Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein zf-UBR (PF02207, IPR003126): Putative zinc finger in N-recognin (UBR box) DZR (PF12773, IPR025874): Double zinc ribbon E3_UbLigase_R4 (PF13764, IPR025704): E3 ubiquitin-protein ligase UBR4 FAM176 (PF14851): FAM176 family |
139 |
USP19 | interactor | 5 | 0.600 | 0.946 | CS (PF04969, IPR007052): CS domain UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase USP19_linker (PF16602): Linker region of USP19 deubiquitinase |
140 |
USP34 | interactor | 4 | 0.667 | 1.667 | Secretin_N_2 (PF07655, IPR011514): Secretin N-terminal domain UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase DUF3517 (PF12030, IPR021905): Domain of unknown function (DUF3517) |
141 |
USP37 | interactor | 16 | 0.467 | 20.054 | UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase UCH_N (PF16674, IPR032069): N-terminal of ubiquitin carboxyl-terminal hydrolase 37 |
142 |
USP39 | oncoprotein | 29 | 0.539 | 43.020 | UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase zf-UBP (PF02148, IPR001607, SM00290): Zn-finger in ubiquitin-hydrolases and other protein |
143 |
USP9X | interactor | 18 | 0.386 | 41.116 | DUF1722 (PF08349, IPR013560): Protein of unknown function (DUF1722) UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase Utp13 (PF08625, IPR013934): Utp13 specific WD40 associated domain |
144 |
VCAM1 | interactor | 27 | 0.453 | 43.390 | C2-set (PF05790, IPR008424): Immunoglobulin C2-set domain I-set (PF07679, IPR013098): Immunoglobulin I-set domain ig (PF00047, IPR013151, SM00409): Immunoglobulin domain V-set (PF07686, IPR013106): Immunoglobulin V-set domain Ig_3 (PF13927): Immunoglobulin domain |
145 |
WDHD1 | interactor | 11 | 0.491 | 13.663 | PVL_ORF50 (PF07768, IPR011688): PVL ORF-50-like family WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat HMG_box (PF00505, IPR009071, SM00398): HMG (high mobility group) box Mcl1_mid (PF12341, IPR022100): Minichromosome loss protein, Mcl1, middle region ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 (PF16529, IPR032401): WD40 region of Ge1, enhancer of mRNA-decapping protein |
146 |
WWOX | suppressor | 26 | 0.505 | 40.261 | adh_short (PF00106, IPR002198): short chain dehydrogenase WW (PF00397, IPR001202, SM00456): WW domain |
147 |
XAB2 | interactor | 24 | 0.598 | 14.946 | NRDE-2 (PF08424, IPR013633): NRDE-2, necessary for RNA interference HAT (PF02184, IPR003107, SM00386): HAT (Half-A-TPR) repeat Suf (PF05843, IPR008847): Suppressor of forked protein (Suf) TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat TPR_12 (PF13424): Tetratricopeptide repeat TPR_14 (PF13428): Tetratricopeptide repeat TPR_19 (PF14559): Tetratricopeptide repeat |
148 |
YBX1 | oncoprotein | 36 | 0.394 | 76.947 | CSD (PF00313, IPR002059): 'Cold-shock' DNA-binding domain PBP1_TM (PF14812, IPR032730): Transmembrane domain of transglycosylase PBP1 at N-terminal FXR_C1 (PF16096, IPR032172): Fragile X-related 1 protein C-terminal region 2 |
149 |
YEATS2 | interactor | 2 | 1.000 | 0 | YEATS (PF03366, IPR005033): YEATS family |
150 |
YWHAG | protein found in more fusions | 25 | 0.467 | 27.036 | 14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein |
151 |
ZBTB10 | interactor | 4 | 0.500 | 1.667 | BTB (PF00651, IPR013069, SM00225): BTB/POZ domain Ribosomal_L37ae (PF01780, IPR002674): Ribosomal L37ae protein family zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-H2C2_5 (PF13909): C2H2-type zinc-finger domain |
152 |
ZMYND11 | suppressor | 10 | 0.583 | 2.677 | DUF1002 (PF06207, IPR009343): Protein of unknown function (DUF1002) DUF1353 (PF07087, IPR010767): Protein of unknown function (DUF1353) PWWP (PF00855, IPR000313, SM00293): PWWP domain zf-MYND (PF01753, IPR002893): MYND finger zf-UBR (PF02207, IPR003126): Putative zinc finger in N-recognin (UBR box) Bromodomain (PF00439, IPR001487, SM00297): Bromodomain |