1 |
SMAD3 | parental protein | 313 | 0.044 | 63570.500 | MH1 (PF03165, IPR003619, SM00523): MH1 domain MH2 (PF03166, IPR001132, SM00524): MH2 domain |
2 |
AATF | oncoprotein | 10 | 0.422 | 12.533 | DARPP-32 (PF05395, IPR008466): Protein phosphatase inhibitor 1/DARPP-32 RR_TM4-6 (PF06459, IPR009460): Ryanodine Receptor TM 4-6 TRAUB (PF08164, IPR012617): Apoptosis-antagonizing transcription factor, C-terminal Vif (PF00559, IPR000475): Retroviral Vif (Viral infectivity) protein AATF-Che1 (PF13339, IPR025160): Apoptosis antagonizing transcription factor |
3 |
ACTB | oncoprotein | 28 | 0.291 | 114.335 | Actin (PF00022, IPR004000, SM00268): Actin |
4 |
ACVR1B | oncoprotein | 6 | 0.733 | 1.517 | Activin_recp (PF01064, IPR000472): Activin types I and II receptor domain Pkinase (PF00069, IPR000719): Protein kinase domain TGF_beta_GS (PF08515, IPR003605, SM00467): Transforming growth factor beta type I GS-motif |
5 |
AES | protein found in more fusions | 12 | 0.218 | 25.353 | TLE_N (PF03920, IPR005617): Groucho/TLE N-terminal Q-rich domain |
6 |
AKT1 | oncoprotein | 39 | 0.266 | 222.446 | PH (PF00169, IPR001849, SM00233): PH domain Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain |
7 |
ANAPC10 | interactor | 5 | 0.800 | 1.000 | ANAPC10 (PF03256, IPR004939): Anaphase-promoting complex, subunit 10 (APC10) |
8 |
ANK3 | interactor | 2 | 1.000 | 0 | BRF1 (PF07741, IPR011665): Brf1-like TBP-binding domain Death (PF00531, IPR000488, SM00005): Death domain ZU5 (PF00791, IPR000906, SM00218): ZU5 domain DUF3008 (PF11450, IPR021553): Protein of unknwon function (DUF3008) DUF3439 (PF11921, IPR024592): Domain of unknown function (DUF3439) Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_4 (PF13637): Ankyrin repeats (many copies) Ank_5 (PF13857): Ankyrin repeats (many copies) |
9 |
APMAP | interactor | 2 | 1.000 | 0 | Str_synth (PF03088, IPR018119): Strictosidine synthase |
10 |
APOB | interactor | 4 | 0.667 | 1.000 | DUF1081 (PF06448, IPR009454): Domain of Unknown Function (DUF1081) DUF1943 (PF09172, IPR015255, SM01169): Domain of unknown function (DUF1943) Phage_holin_6_1 (PF09682, IPR010026): Bacteriophage holin of superfamily 6 (Holin_LLH) Vitellogenin_N (PF01347, IPR001747, SM00638): Lipoprotein amino terminal region DUF2807 (PF10988, IPR021255): Putative auto-transporter adhesin, head GIN domain ApoB100_C (PF12491, IPR022176): Apolipoprotein B100 C terminal |
11 |
APP | protein found in more fusions | 58 | 0.085 | 1068.798 | APP_N (PF02177, IPR015849, SM00006): Amyloid A4 N-terminal heparin-binding Beta-APP (PF03494, IPR013803): Beta-amyloid peptide (beta-APP) BUD22 (PF09073, IPR015158): BUD22 IncA (PF04156, IPR007285): IncA protein Kunitz_BPTI (PF00014, IPR002223, SM00131): Kunitz/Bovine pancreatic trypsin inhibitor domain APP_amyloid (PF10515, IPR019543): beta-amyloid precursor protein C-terminus APP_Cu_bd (PF12924, IPR011178): Copper-binding of amyloid precursor, CuBD APP_E2 (PF12925, IPR024329): E2 domain of amyloid precursor protein |
12 |
AR | oncoprotein | 54 | 0.230 | 474.778 | Androgen_recep (PF02166, IPR001103): Androgen receptor zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor |
13 |
ARID1A | suppressor | 13 | 0.538 | 11.048 | ARID (PF01388, IPR001606, SM00501): ARID/BRIGHT DNA binding domain Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein TAF4 (PF05236, IPR007900): Transcription initiation factor TFIID component TAF4 family YscJ_FliF_C (PF08345, IPR013556): Flagellar M-ring protein C-terminal TAT_signal (PF10518, IPR019546): TAT (twin-arginine translocation) pathway signal sequence BAF250_C (PF12031, IPR021906): SWI/SNF-like complex subunit BAF250/Osa Keratin_2_tail (PF16210, IPR032449): Keratin type II cytoskeletal 1 tail |
14 |
ATF2 | oncoprotein | 26 | 0.310 | 106.091 | bZIP_1 (PF00170, IPR004827): bZIP transcription factor zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type |
15 |
ATF3 | suppressor | 23 | 0.381 | 43.303 | bZIP_1 (PF00170, IPR004827): bZIP transcription factor |
16 |
ATXN2L | interactor | 4 | 0.500 | 2.182 | LsmAD (PF06741, IPR009604): LsmAD domain PAM2 (PF07145, IPR009818): Ataxin-2 C-terminal region SM-ATX (PF14438, IPR025852): Ataxin 2 SM domain |
17 |
BACH1 | interactor | 8 | 0.619 | 3.308 | BTB (PF00651, IPR013069, SM00225): BTB/POZ domain bZIP_Maf (PF03131, IPR004826): bZIP Maf transcription factor Cep57_CLD_2 (PF14197, IPR025925): Centrosome localisation domain of PPC89 |
18 |
BAG3 | oncoprotein | 12 | 0.291 | 32.138 | BAG (PF02179, IPR003103, SM00264): BAG domain WW (PF00397, IPR001202, SM00456): WW domain |
19 |
BLZF1 | interactor | 5 | 0.500 | 3.667 | DASH_Hsk3 (PF08227, IPR013183): DASH complex subunit Hsk3 like DUF1178 (PF06676, IPR009562): Protein of unknown function (DUF1178) ZapB (PF06005, IPR009252): Cell division protein ZapB JIP_LZII (PF16471, IPR032486): JNK-interacting protein leucine zipper II |
20 |
BMP7 | interactor | 3 | 1.000 | 0 | TGFb_propeptide (PF00688, IPR001111): TGF-beta propeptide TGF_beta (PF00019, IPR001839, SM00204): Transforming growth factor beta like domain |
21 |
BPTF | interactor | 3 | 0.667 | 0.167 | Arc_PepC_II (PF06847, IPR009655): Archaeal Peptidase A24 C-terminus Type II CobT (PF06213, IPR006538): Cobalamin biosynthesis protein CobT DDT (PF02791, IPR004022, SM00571): DDT domain DUF1764 (PF08576, IPR013885): Eukaryotic protein of unknown function (DUF1764) GRP (PF07172, IPR010800): Glycine rich protein family OAD_gamma (PF04277, IPR005899): Oxaloacetate decarboxylase, gamma chain PHD (PF00628, IPR019787, SM00249): PHD-finger SDA1 (PF05285, IPR007949): SDA1 Trypan_PARP (PF05887, IPR008882): Procyclic acidic repetitive protein (PARP) Bromodomain (PF00439, IPR001487, SM00297): Bromodomain WHIM1 (PF15612, IPR028942): WSTF, HB1, Itc1p, MBD9 motif 1 WSD (PF15613, IPR028941): Williams-Beuren syndrome DDT (WSD), D-TOX E motif CCSAP (PF15748, IPR029774): Centriole, cilia and spindle-associated PNISR (PF15996, IPR031937): Arginine/serine-rich protein PNISR |
22 |
BRCA1 | suppressor | 52 | 0.245 | 451.782 | BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger) BRCT_assoc (PF12820, IPR025994): Serine-rich domain associated with BRCT |
23 |
BRCA2 | suppressor | 11 | 0.582 | 8.611 | BRCA-2_helical (PF09169, IPR015252): BRCA2, helical BRCA-2_OB1 (PF09103, IPR015187): BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 BRCA-2_OB3 (PF09104, IPR015188): BRCA2, oligonucleotide/oligosaccharide-binding, domain 3 BRCA2 (PF00634, IPR002093): BRCA2 repeat Tower (PF09121, IPR015205): Tower |
24 |
BTRC | oncoprotein | 31 | 0.269 | 171.008 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Beta-TrCP_D (PF12125, IPR021977, SM01028): D domain of beta-TrCP ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain F-box-like (PF12937, IPR001810): F-box-like |
25 |
BUB3 | interactor | 8 | 0.536 | 4.169 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat |
26 |
C10orf54 | interactor | 1 | 0 | 0 | V-set (PF07686, IPR013106): Immunoglobulin V-set domain |
27 |
C1orf116 | interactor | 3 | 0.667 | 0.069 | SARG (PF15385): Specifically androgen-regulated gene protein |
28 |
CAMK2G | interactor | 5 | 0.700 | 0.683 | CaMKII_AD (PF08332, IPR013543): Calcium/calmodulin dependent protein kinase II association domain Pkinase (PF00069, IPR000719): Protein kinase domain |
29 |
CBL | suppressor | 17 | 0.242 | 53.888 | Cbl_N (PF02262, IPR003153): CBL proto-oncogene N-terminal domain 1 Cbl_N2 (PF02761, IPR014741): CBL proto-oncogene N-terminus, EF hand-like domain Cbl_N3 (PF02762, IPR014742): CBL proto-oncogene N-terminus, SH2-like domain UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain Prok-RING_4 (PF14447): Prokaryotic RING finger family 4 zf-RING_4 (PF14570): RING/Ubox like zinc-binding domain |
30 |
CCDC33 | interactor | 8 | 0.500 | 9.141 | C2 (PF00168, IPR000008, SM00239): C2 domain DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972) Pox_A_type_inc (PF04508, IPR007596): Viral A-type inclusion protein repeat SlyX (PF04102, IPR007236): SlyX |
31 |
CDC16 | interactor | 9 | 0.556 | 7.666 | Dynein_light (PF01221, IPR001372): Dynein light chain type 1 TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat ANAPC3 (PF12895): Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 (PF13424): Tetratricopeptide repeat TPR_17 (PF13431): Tetratricopeptide repeat TPR_16 (PF13432): Tetratricopeptide repeat SRP_TPR_like (PF17004, IPR031545): Putative TPR-like repeat |
32 |
CDC25A | oncoprotein | 7 | 0.476 | 6.147 | M-inducer_phosp (PF06617, IPR000751): M-phase inducer phosphatase Rhodanese (PF00581, IPR001763, SM00450): Rhodanese-like domain |
33 |
CDC27 | oncoprotein | 16 | 0.352 | 33.348 | TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat ANAPC3 (PF12895): Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 (PF13414, IPR011990): TPR repeat TPR_12 (PF13424): Tetratricopeptide repeat |
34 |
CDK11A | oncoprotein | 3 | 0.667 | 0.286 | DDHD (PF02862, IPR004177, SM01127): DDHD domain eIF_4EBP (PF05456, IPR008606): Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) Pkinase (PF00069, IPR000719): Protein kinase domain RIO1 (PF01163, IPR018934): RIO1 family DUF4355 (PF14265, IPR025580): Domain of unknown function (DUF4355) DHHW (PF14286, IPR025945): DHHW protein DUF4748 (PF15932, IPR031833): Domain of unknown function (DUF4748) |
35 |
CDK2 | suppressor | 41 | 0.283 | 242.739 | Kdo (PF06293, IPR010440): Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase (PF00069, IPR000719): Protein kinase domain |
36 |
CDK4 | oncoprotein | 15 | 0.343 | 24.867 | Pkinase (PF00069, IPR000719): Protein kinase domain |
37 |
CDK8 | interactor | 20 | 0.503 | 27.487 | Pkinase (PF00069, IPR000719): Protein kinase domain |
38 |
CDK9 | protein found in more fusions | 15 | 0.484 | 12.953 | Pkinase (PF00069, IPR000719): Protein kinase domain |
39 |
CDKN1A | suppressor | 27 | 0.348 | 87.506 | CDI (PF02234, IPR003175): Cyclin-dependent kinase inhibitor |
40 |
CEBPA | suppressor | 28 | 0.345 | 76.356 | Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator DUF2514 (PF10721, IPR019659): Protein of unknown function (DUF2514) bZIP_2 (PF07716, IPR004827, SM00338): Basic region leucine zipper |
41 |
CEBPB | oncoprotein | 31 | 0.446 | 61.656 | RhlB (PF12300, IPR022077): ATP-dependent RNA helicase RhlB FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 |
42 |
CEBPD | suppressor | 10 | 0.644 | 3.385 | bZIP_2 (PF07716, IPR004827, SM00338): Basic region leucine zipper BST2 (PF16716, IPR024886): Bone marrow stromal antigen 2 |
43 |
CFDP1 | interactor | 2 | 1.000 | 0 | BCNT (PF07572, IPR011421): Bucentaur or craniofacial development DUF789 (PF05623, IPR008507): Protein of unknown function (DUF789) YL1 (PF05764, IPR008895): YL1 nuclear protein DUF4048 (PF13257, IPR025122): Domain of unknown function (DUF4048) |
44 |
CFH | oncoprotein | 4 | 1.000 | 0 | DUF1962 (PF09227, IPR015308): Domain of unknown function (DUF1962) Sushi (PF00084, IPR000436, SM00032): Sushi repeat (SCR repeat) |
45 |
CFLAR | oncoprotein | 7 | 0.533 | 4.686 | DED (PF01335, IPR001875, SM00031): Death effector domain Peptidase_C14 (PF00656, IPR011600): Caspase domain |
46 |
CHD8 | oncoprotein | 9 | 0.472 | 9.082 | BUD22 (PF09073, IPR015158): BUD22 CHDCT2 (PF08074, IPR012957): CHDCT2 (NUC038) domain Chromo (PF00385, IPR023780, SM00298): Chromo (CHRromatin Organisation MOdifier) domain SelP_N (PF04592, IPR007671): Selenoprotein P, N terminal region SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain BRK (PF07533, IPR006576, SM00592): BRK domain SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain FAM176 (PF14851): FAM176 family Myb_DNA-bind_7 (PF15963): Myb DNA-binding like |
47 |
CHRD | interactor | 2 | 1.000 | 0 | CHRD (PF07452, IPR010895, SM00754): CHRD domain VWC (PF00093, IPR001007, SM00214): von Willebrand factor type C domain |
48 |
CHUK | suppressor | 21 | 0.468 | 41.156 | Pkinase (PF00069, IPR000719): Protein kinase domain IKKbetaNEMObind (PF12179, IPR022007): I-kappa-kinase-beta NEMO binding domain |
49 |
CITED2 | suppressor | 5 | 0.900 | 0.118 | CITED (PF04487, IPR007576): CITED |
50 |
CORO1A | oncoprotein | 4 | 0.500 | 2.500 | DUF1899 (PF08953, IPR015048, SM01166): Domain of unknown function (DUF1899) Trimer_CC (PF08954, IPR015049, SM01167): Trimerisation motif WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain WD40_4 (PF16300): Type of WD40 repeat |
51 |
CPSF7 | interactor | 8 | 0.429 | 8.478 | CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term PRIMA1 (PF16101): Proline-rich membrane anchor 1 |
52 |
CPTP | interactor | 1 | 0 | 0 | GLTP (PF08718, IPR014830): Glycolipid transfer protein (GLTP) |
53 |
CREBBP | suppressor | 69 | 0.246 | 701.864 | Creb_binding (PF09030, IPR014744): Creb binding DUF902 (PF06001, IPR010303): Domain of Unknown Function (DUF902) Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region KIX (PF02172, IPR003101): KIX domain MAS20 (PF02064, IPR002056): MAS20 protein import receptor TPX2 (PF06886, IPR027329): Targeting protein for Xklp2 (TPX2) zf-TAZ (PF02135, IPR000197, SM00551): TAZ zinc finger ANAPC_CDC26 (PF10471, IPR018860): Anaphase-promoting complex APC subunit CDC26 HAT_KAT11 (PF08214, IPR013178): Histone acetylation protein Bromodomain (PF00439, IPR001487, SM00297): Bromodomain ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type DUF3729 (PF12526, IPR022202): Protein of unknown function (DUF3729) DUF4834 (PF16118, IPR032272): Domain of unknown function (DUF4834) |
54 |
CSH2 | interactor | 4 | 1.000 | 0 | Hormone_1 (PF00103, IPR001400): Somatotropin hormone family |
55 |
CSNK1D | interactor | 11 | 0.418 | 10.234 | Pkinase (PF00069, IPR000719): Protein kinase domain |
56 |
CSNK1G2 | interactor | 2 | 1.000 | 0 | Pkinase (PF00069, IPR000719): Protein kinase domain CK1gamma_C (PF12605, IPR022247): Casein kinase 1 gamma C terminal |
57 |
CTCF | suppressor | 5 | 0.400 | 4.317 | cwf18 (PF08315, IPR013169): cwf18 pre-mRNA splicing factor zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_4 (PF13894): C2H2-type zinc finger zf-H2C2_5 (PF13909): C2H2-type zinc-finger domain PBP1_TM (PF14812, IPR032730): Transmembrane domain of transglycosylase PBP1 at N-terminal |
58 |
CTNNB1 | oncoprotein | 57 | 0.210 | 587.389 | Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat Atx10homo_assoc (PF09759, IPR019156): Spinocerebellar ataxia type 10 protein domain DUF3361 (PF11841, IPR024574): Domain of unknown function (DUF3361) HEAT_EZ (PF13513): HEAT-like repeat |
59 |
CUL1 | suppressor | 37 | 0.224 | 260.432 | Cullin (PF00888, IPR001373, SM00182): Cullin family Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain |
60 |
CXXC5 | suppressor | 6 | 0.400 | 3.556 | Filament_head (PF04732, IPR006821): Intermediate filament head (DNA binding) region zf-CXXC (PF02008, IPR002857): CXXC zinc finger domain TAT_signal (PF10518, IPR019546): TAT (twin-arginine translocation) pathway signal sequence |
61 |
CYP11A1 | interactor | 3 | 1.000 | 0 | p450 (PF00067, IPR001128): Cytochrome P450 |
62 |
DAB2 | suppressor | 11 | 0.327 | 19.004 | PID (PF00640, IPR006020, SM00462): Phosphotyrosine interaction domain (PTB/PID) zf-C2H2_assoc3 (PF16637): Putative zinc-finger between two C2H2 zinc-fingers on Patz |
63 |
DACH1 | suppressor | 7 | 0.600 | 1.837 | DUF508 (PF04370, IPR007465): Domain of unknown function (DUF508) Pap_E4 (PF02711, IPR003861): E4 protein Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein Secretin_N_2 (PF07655, IPR011514): Secretin N-terminal domain Ski_Sno (PF02437, IPR003380): SKI/SNO/DAC family Macoilin (PF09726, IPR019130): Transmembrane protein SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein |
64 |
DCAF7 | interactor | 10 | 0.444 | 11.189 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat |
65 |
DDX3X | suppressor | 12 | 0.530 | 7.607 | DEAD (PF00270, IPR011545): DEAD/DEAH box helicase DUF755 (PF05501, IPR008474): Domain of unknown function (DUF755) Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain |
66 |
DDX3Y | interactor | 3 | 1.000 | 0 | DEAD (PF00270, IPR011545): DEAD/DEAH box helicase Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain |
67 |
DDX4 | interactor | 2 | 1.000 | 0 | DEAD (PF00270, IPR011545): DEAD/DEAH box helicase Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain |
68 |
DDX5 | oncoprotein | 26 | 0.377 | 70.064 | DEAD (PF00270, IPR011545): DEAD/DEAH box helicase P68HR (PF08061, IPR012587): P68HR (NUC004) repeat ResIII (PF04851, IPR006935): Type III restriction enzyme, res subunit Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain |
69 |
DEDD | interactor | 4 | 0.667 | 0.667 | DED (PF01335, IPR001875, SM00031): Death effector domain |
70 |
DHX8 | protein found in more fusions | 7 | 0.467 | 6.071 | DEAD (PF00270, IPR011545): DEAD/DEAH box helicase OB_NTP_bind (PF07717, IPR011709): Oligonucleotide/oligosaccharide-binding (OB)-fold DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777) HA2 (PF04408, IPR007502, SM00847): Helicase associated domain (HA2) S1 (PF00575, IPR003029, SM00316): S1 RNA binding domain Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain |
71 |
DNAJA2 | interactor | 9 | 0.556 | 5.917 | DnaJ (PF00226, IPR001623, SM00271): DnaJ domain DnaJ_C (PF01556, IPR002939): DnaJ C terminal domain |
72 |
DNAJB4 | suppressor | 4 | 0.667 | 1.500 | DnaJ (PF00226, IPR001623, SM00271): DnaJ domain DnaJ_C (PF01556, IPR002939): DnaJ C terminal domain |
73 |
DNMT3L | interactor | 24 | 0.293 | 103.779 | CEBP_ZZ (PF16366, IPR032296): Cytoplasmic polyadenylation element-binding protein ZZ domain |
74 |
DOCK9 | interactor | 2 | 1.000 | 0 | DHR-2 (PF06920, IPR010703): Dock homology region 2 PH (PF00169, IPR001849, SM00233): PH domain DUF3398 (PF11878, IPR021816): Domain of unknown function (DUF3398) DOCK-C2 (PF14429, IPR027007): C2 domain in Dock180 and Zizimin proteins |
75 |
DVL1 | interactor | 12 | 0.564 | 7.509 | DEP (PF00610, IPR000591, SM00049): Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Dishevelled (PF02377, IPR003351): Dishevelled specific domain PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) DIX (PF00778, IPR001158, SM00021): DIX domain Dsh_C (PF12316, IPR024580): Segment polarity protein dishevelled (Dsh) C terminal |
76 |
DYRK1A | oncoprotein | 8 | 0.524 | 3.836 | DUF755 (PF05501, IPR008474): Domain of unknown function (DUF755) Filament_head (PF04732, IPR006821): Intermediate filament head (DNA binding) region Pkinase (PF00069, IPR000719): Protein kinase domain FAM199X (PF15814, IPR029672): Protein family FAM199X |
77 |
E2F4 | suppressor | 12 | 0.470 | 9.033 | E2F_TDP (PF02319, IPR003316): E2F/DP family winged-helix DNA-binding domain Pheromone (PF08015, IPR012597): Fungal mating-type pheromone SPX (PF03105, IPR004331): SPX domain DUF3584 (PF12128, IPR021979): Protein of unknown function (DUF3584) E2F_CC-MB (PF16421, IPR032198): E2F transcription factor CC-MB domain |
78 |
EBI3 | interactor | 1 | 0 | 0 | fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain |
79 |
EID2 | interactor | 4 | 1.000 | 0 | Antimicrobial_5 (PF08026, IPR012524): Bee antimicrobial peptide |
80 |
EIF4B | interactor | 6 | 0.400 | 2.552 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3774 (PF12609, IPR022251): Wound-induced protein PROL5-SMR (PF15621, IPR026288): Proline-rich submaxillary gland androgen-regulated family |
81 |
ELAC2 | oncoprotein | 5 | 0.600 | 2.213 | Synthase_beta (PF11421, IPR020971): ATP synthase F1 beta subunit Lactamase_B_2 (PF12706, IPR001279): Beta-lactamase superfamily domain Lactamase_B_4 (PF13691, IPR027794): tRNase Z endonuclease |
82 |
EP300 | oncoprotein | 88 | 0.175 | 1635.409 | Creb_binding (PF09030, IPR014744): Creb binding DUF902 (PF06001, IPR010303): Domain of Unknown Function (DUF902) Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region KIX (PF02172, IPR003101): KIX domain RR_TM4-6 (PF06459, IPR009460): Ryanodine Receptor TM 4-6 TPX2 (PF06886, IPR027329): Targeting protein for Xklp2 (TPX2) zf-TAZ (PF02135, IPR000197, SM00551): TAZ zinc finger HAT_KAT11 (PF08214, IPR013178): Histone acetylation protein Bromodomain (PF00439, IPR001487, SM00297): Bromodomain ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type |
83 |
EPAS1 | suppressor | 23 | 0.299 | 70.873 | Corona_I (PF03187, IPR004876): Corona nucleocapsid I protein HIF-1a_CTAD (PF08778, IPR014887): HIF-1 alpha C terminal transactivation domain HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain PAS (PF00989, IPR013767, SM00091): PAS fold HIF-1 (PF11413, IPR021537): Hypoxia-inducible factor-1 PAS_11 (PF14598): PAS domain |
84 |
EPB41L5 | interactor | 4 | 0.667 | 0.174 | FA (PF08736, IPR014847): FERM adjacent (FA) FERM_C (PF09380, IPR018980): FERM C-terminal PH-like domain FERM_M (PF00373, IPR019748): FERM central domain FERM_N (PF09379, IPR018979): FERM N-terminal domain |
85 |
ERBIN | oncoprotein | 14 | 0.526 | 16.649 | LRR_1 (PF00560, IPR001611): Leucine Rich Repeat Neur_chan_memb (PF02932, IPR006029): Neurotransmitter-gated ion-channel transmembrane region PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies) LRR_8 (PF13855, IPR001611): Leucine rich repeat |
86 |
ESR1 | suppressor | 77 | 0.180 | 1226.665 | Oest_recep (PF02159, IPR001292): Oestrogen receptor zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor ESR1_C (PF12743, IPR024736): Oestrogen-type nuclear receptor final C-terminal |
87 |
ETS1 | oncoprotein | 20 | 0.474 | 39.387 | Ets (PF00178, IPR000418, SM00413): Ets-domain SAM_PNT (PF02198, IPR003118, SM00251): Sterile alpha motif (SAM)/Pointed domain |
88 |
FAM83G | interactor | 2 | 1.000 | 0 | DUF1669 (PF07894, IPR012461): Protein of unknown function (DUF1669) Trypan_PARP (PF05887, IPR008882): Procyclic acidic repetitive protein (PARP) |
89 |
FBLN1 | suppressor | 6 | 0.600 | 2.178 | ANATO (PF01821, IPR000020, SM00104): Anaphylotoxin-like domain EGF (PF00008, IPR000742, SM00181): EGF-like domain EGF_CA (PF07645, IPR001881, SM00179): Calcium-binding EGF domain cEGF (PF12662, IPR026823): Complement Clr-like EGF-like FXa_inhibition (PF14670): Coagulation Factor Xa inhibitory site |
90 |
FHL1 | suppressor | 12 | 0.652 | 6.043 | LIM (PF00412, IPR001781, SM00132): LIM domain zf-FCS (PF06467, IPR010507): MYM-type Zinc finger with FCS sequence motif |
91 |
FHL2 | oncoprotein | 25 | 0.351 | 75.164 | LIM (PF00412, IPR001781, SM00132): LIM domain zf-ribbon_3 (PF13248): zinc-ribbon domain |
92 |
FHL3 | interactor | 13 | 0.303 | 33.806 | LIM (PF00412, IPR001781, SM00132): LIM domain Med27 (PF11571, IPR021627): Mediator complex subunit 27 |
93 |
FLI1 | oncoprotein | 5 | 0.500 | 1.906 | Ets (PF00178, IPR000418, SM00413): Ets-domain SAM_PNT (PF02198, IPR003118, SM00251): Sterile alpha motif (SAM)/Pointed domain |
94 |
FLNA | suppressor | 15 | 0.476 | 22.439 | CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain Filamin (PF00630, IPR017868): Filamin/ABP280 repeat |
95 |
FOS | oncoprotein | 25 | 0.402 | 56.219 | bZIP_1 (PF00170, IPR004827): bZIP transcription factor |
96 |
FOXH1 | interactor | 6 | 0.600 | 3.286 | Forkhead (PF00250, IPR001766, SM00339): Forkhead domain |
97 |
FOXL2 | suppressor | 1 | 0 | 0 | K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain Forkhead (PF00250, IPR001766, SM00339): Forkhead domain PRIMA1 (PF16101): Proline-rich membrane anchor 1 |
98 |
FOXM1 | oncoprotein | 8 | 0.429 | 8.252 | EspF (PF04806, IPR006891): EspF protein repeat Forkhead (PF00250, IPR001766, SM00339): Forkhead domain |
99 |
FOXO1 | suppressor | 19 | 0.484 | 20.422 | K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain Forkhead (PF00250, IPR001766, SM00339): Forkhead domain FOXO_KIX_bdg (PF16675, IPR032068): KIX-binding domain of forkhead box O, CR2 FOXO-TAD (PF16676, IPR032067): Transactivation domain of FOXO protein family |
100 |
FOXO3 | suppressor | 19 | 0.480 | 26.835 | Lin-8 (PF03353, IPR005020): Ras-mediated vulval-induction antagonist Forkhead (PF00250, IPR001766, SM00339): Forkhead domain FOXO_KIX_bdg (PF16675, IPR032068): KIX-binding domain of forkhead box O, CR2 FOXO-TAD (PF16676, IPR032067): Transactivation domain of FOXO protein family |
101 |
FOXO4 | suppressor | 10 | 0.533 | 5.073 | Forkhead (PF00250, IPR001766, SM00339): Forkhead domain FOXO_KIX_bdg (PF16675, IPR032068): KIX-binding domain of forkhead box O, CR2 FOXO-TAD (PF16676, IPR032067): Transactivation domain of FOXO protein family |
102 |
GGA1 | oncoprotein | 4 | 0.667 | 0.500 | Alpha_adaptinC2 (PF02883, IPR008152, SM00809): Adaptin C-terminal domain GAT (PF03127, IPR004152): GAT domain Hormone_3 (PF00159, IPR001955): Pancreatic hormone peptide VHS (PF00790, IPR002014, SM00288): VHS domain AP3B1_C (PF14796, IPR029390): Clathrin-adaptor complex-3 beta-1 subunit C-terminal |
103 |
GIT2 | interactor | 5 | 0.500 | 3.000 | ArfGap (PF01412, IPR001164, SM00105): Putative GTPase activating protein for Arf Sen15 (PF09631, IPR018593): Sen15 protein GIT_SHD (PF08518, IPR013724, SM00555): Spa2 homology domain (SHD) of GIT GIT1_C (PF12205, IPR022018): G protein-coupled receptor kinase-interacting protein 1 C term Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) DUF4482 (PF14818, IPR027882): Domain of unknown function (DUF4482) GIT_CC (PF16559, IPR032352): GIT coiled-coil Rho guanine nucleotide exchange factor |
104 |
GMEB1 | interactor | 3 | 1.000 | 0 | Adeno_PV (PF03910, IPR005608): Adenovirus minor core protein PV SAND (PF01342, IPR000770, SM00258): SAND domain |
105 |
GRIP1 | protein found in more fusions | 12 | 0.764 | 1.838 | PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) |
106 |
GSK3B | suppressor | 30 | 0.273 | 135.955 | Pkinase (PF00069, IPR000719): Protein kinase domain |
107 |
HDAC1 | suppressor | 72 | 0.203 | 1027.597 | FSAP_sig_propep (PF03032, IPR004275): Frog skin active peptide family signal and propeptide Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain |
108 |
HDAC4 | oncoprotein | 27 | 0.268 | 89.825 | Borrelia_P83 (PF05262, IPR007926): Borrelia P83/100 protein Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit HDAC4_Gln (PF12203, IPR024643): Glutamine rich N terminal domain of histone deacetylase 4 |
109 |
HDAC5 | protein found in more fusions | 33 | 0.228 | 199.698 | Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain NOA36 (PF06524, IPR010531): NOA36 protein Activator_LAG-3 (PF11498, IPR021587): Transcriptional activator LAG-3 HDAC4_Gln (PF12203, IPR024643): Glutamine rich N terminal domain of histone deacetylase 4 |
110 |
HEY1 | oncoprotein | 4 | 0.667 | 0.508 | Hairy_orange (PF07527, IPR003650): Hairy Orange HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain HTH_Crp_2 (PF13545, IPR012318): Crp-like helix-turn-helix domain |
111 |
HEYL | interactor | 5 | 0.500 | 1.291 | Hairy_orange (PF07527, IPR003650): Hairy Orange HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain |
112 |
HGS | interactor | 18 | 0.242 | 73.778 | FYVE (PF01363, IPR000306, SM00064): FYVE zinc finger UIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif VHS (PF00790, IPR002014, SM00288): VHS domain EF-1_beta_acid (PF10587, IPR018940): Eukaryotic elongation factor 1 beta central acidic region Hrs_helical (PF12210, IPR024641): Hepatocyte growth factor-regulated tyrosine kinase substrate PIEZO (PF15917, IPR031805): Piezo |
113 |
HIF1A | suppressor | 32 | 0.393 | 110.680 | Dicty_REP (PF05086, IPR007778): Dictyostelium (Slime Mold) REP protein HIF-1a_CTAD (PF08778, IPR014887): HIF-1 alpha C terminal transactivation domain HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain PAS (PF00989, IPR013767, SM00091): PAS fold PAS_3 (PF08447, IPR013655): PAS fold HIF-1 (PF11413, IPR021537): Hypoxia-inducible factor-1 |
114 |
HIPK2 | suppressor | 19 | 0.386 | 43.501 | Kdo (PF06293, IPR010440): Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase (PF00069, IPR000719): Protein kinase domain |
115 |
HIVEP1 | suppressor | 5 | 0.400 | 2.206 | PHD (PF00628, IPR019787, SM00249): PHD-finger PyrI_C (PF02748, IPR020542): Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-C2H2_2 (PF12756, IPR015880): C2H2 type zinc-finger (2 copies) zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-H2C2_5 (PF13909): C2H2-type zinc-finger domain zf-C2H2_7 (PF15269): Zinc-finger |
116 |
HNF4A | suppressor | 18 | 0.441 | 27.337 | zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor |
117 |
HNRNPK | oncoprotein | 29 | 0.317 | 116.208 | ROKNT (PF08067, IPR012987): ROKNT (NUC014) domain KH_1 (PF00013, IPR004088, SM00322): KH domain |
118 |
HOXC11 | oncoprotein | 4 | 0.500 | 0.668 | DUF3528 (PF12045, IPR021918): Protein of unknown function (DUF3528) |
119 |
HP | interactor | 3 | 0.667 | 0.667 | Sushi (PF00084, IPR000436, SM00032): Sushi repeat (SCR repeat) Trypsin (PF00089, IPR001254, SM00020): Trypsin |
120 |
HSPA4 | interactor | 32 | 0.250 | 177.459 | Herpes_ICP4_N (PF03584, IPR005206): Herpesvirus ICP4-like protein N-terminal region HSP70 (PF00012, IPR013126): Hsp70 protein TP53IP5 (PF15331, IPR029290): Cellular tumour antigen p53-inducible 5 |
121 |
IRF7 | interactor | 10 | 0.556 | 10.272 | IRF (PF00605, IPR001346, SM00348): Interferon regulatory factor transcription factor IRF-3 (PF10401, IPR019471): Interferon-regulatory factor 3 |
122 |
IRS1 | interactor | 9 | 0.528 | 5.632 | CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal IRS (PF02174, IPR002404, SM00310): PTB domain (IRS-1 type) PH (PF00169, IPR001849, SM00233): PH domain |
123 |
ISL1 | interactor | 5 | 0.667 | 0.248 | LIM (PF00412, IPR001781, SM00132): LIM domain Homeobox (PF00046, IPR001356, SM00389): Homeobox domain |
124 |
ITCH | interactor | 27 | 0.249 | 134.101 | C2 (PF00168, IPR000008, SM00239): C2 domain WW (PF00397, IPR001202, SM00456): WW domain HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase) |
125 |
ITGB4 | oncoprotein | 6 | 0.467 | 3.952 | Calx-beta (PF03160, IPR003644, SM00237): Calx-beta domain EGF_2 (PF07974, IPR013111): EGF-like domain fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain Integrin_B_tail (PF07965, IPR012896): Integrin beta tail domain SEA (PF01390, IPR000082, SM00200): SEA domain STOP (PF05217, IPR024963): STOP protein Integrin_beta (PF00362, IPR002369, SM00187): Integrin, beta chain PSI_integrin (PF17205): Integrin plexin domain |
126 |
JUN | oncoprotein | 49 | 0.317 | 280.802 | bZIP_1 (PF00170, IPR004827): bZIP transcription factor Jun (PF03957, IPR005643): Jun-like transcription factor |
127 |
JUNB | oncoprotein | 12 | 0.485 | 7.135 | bZIP_1 (PF00170, IPR004827): bZIP transcription factor Jun (PF03957, IPR005643): Jun-like transcription factor |
128 |
JUND | oncoprotein | 12 | 0.424 | 12.682 | bZIP_1 (PF00170, IPR004827): bZIP transcription factor Jun (PF03957, IPR005643): Jun-like transcription factor |
129 |
KANSL1 | interactor | 3 | 0.667 | 1.000 | PEHE (PF15275, IPR029332): PEHE domain |
130 |
KAT2A | interactor | 17 | 0.358 | 25.545 | Acetyltransf_1 (PF00583, IPR000182): Acetyltransferase (GNAT) family PCAF_N (PF06466, IPR009464): PCAF (P300/CBP-associated factor) N-terminal domain Bromodomain (PF00439, IPR001487, SM00297): Bromodomain NICE-1 (PF15845, IPR031698): Cysteine-rich C-terminal 1 family |
131 |
KAT2B | protein found in more fusions | 34 | 0.333 | 133.736 | Acetyltransf_1 (PF00583, IPR000182): Acetyltransferase (GNAT) family PCAF_N (PF06466, IPR009464): PCAF (P300/CBP-associated factor) N-terminal domain Bromodomain (PF00439, IPR001487, SM00297): Bromodomain |
132 |
KDM2A | interactor | 4 | 0.667 | 0.917 | JmjC (PF02373, IPR003347, SM00558): JmjC domain, hydroxylase Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein zf-CXXC (PF02008, IPR002857): CXXC zinc finger domain F-box (PF00646, IPR001810, SM00256): F-box domain DZR (PF12773, IPR025874): Double zinc ribbon LRR_6 (PF13516, IPR001611): Leucine Rich repeat LRR_8 (PF13855, IPR001611): Leucine rich repeat PHD_4 (PF16866, IPR019787): PHD-finger |
133 |
KDM5C | oncoprotein | 4 | 0.667 | 0.182 | ARID (PF01388, IPR001606, SM00501): ARID/BRIGHT DNA binding domain JmjC (PF02373, IPR003347, SM00558): JmjC domain, hydroxylase JmjN (PF02375, IPR003349, SM00545): jmjN domain PHD (PF00628, IPR019787, SM00249): PHD-finger PLU-1 (PF08429, IPR013637): PLU-1-like protein FYVE_2 (PF02318, IPR010911): FYVE-type zinc finger zf-C5HC2 (PF02928, IPR004198): C5HC2 zinc finger |
134 |
KDM6B | interactor | 4 | 1.000 | 0 | Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator JmjC (PF02373, IPR003347, SM00558): JmjC domain, hydroxylase Mucin (PF01456, IPR000458): Mucin-like glycoprotein |
135 |
KLF5 | suppressor | 17 | 0.551 | 15.212 | zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain |
136 |
KMT2B | oncoprotein | 4 | 0.500 | 0.700 | FLO_LFY (PF01698, IPR002910): Floricaula / Leafy protein FYRC (PF05965, IPR003889, SM00542): F/Y rich C-terminus FYRN (PF05964, IPR003888, SM00541): F/Y-rich N-terminus GRP (PF07172, IPR010800): Glycine rich protein family PHD (PF00628, IPR019787, SM00249): PHD-finger SET (PF00856, IPR001214, SM00317): SET domain zf-CXXC (PF02008, IPR002857): CXXC zinc finger domain Bromodomain (PF00439, IPR001487, SM00297): Bromodomain Fer4_2 (PF12797, IPR001450): 4Fe-4S binding domain zf-HC5HC2H (PF13771): PHD-like zinc-binding domain FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 AIM3 (PF17096, IPR031370): Altered inheritance of mitochondria protein 3 |
137 |
KPNB1 | protein found in more fusions | 22 | 0.267 | 80.847 | Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat HEAT (PF02985, IPR000357): HEAT repeat IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain V-ATPase_H_C (PF11698, IPR011987): V-ATPase subunit H CLASP_N (PF12348, IPR024395): CLASP N terminal Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1 HEAT_EZ (PF13513): HEAT-like repeat |
138 |
LACRT | interactor | 3 | 1.000 | 0 | NA |
139 |
LBP | interactor | 2 | 1.000 | 0 | LBP_BPI_CETP (PF01273, IPR017942, SM00328): LBP / BPI / CETP family, N-terminal domain LBP_BPI_CETP_C (PF02886, IPR001124, SM00329): LBP / BPI / CETP family, C-terminal domain |
140 |
LCK | oncoprotein | 12 | 0.382 | 17.668 | Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain |
141 |
LDLRAD4 | interactor | 12 | 0.364 | 21.679 | Ldl_recept_a (PF00057, IPR002172, SM00192): Low-density lipoprotein receptor domain class A DUF2615 (PF11027, IPR020309): Protein of unknown function (DUF2615) |
142 |
LEF1 | oncoprotein | 12 | 0.621 | 12.264 | CTNNB1_binding (PF08347, IPR013558): N-terminal CTNNB1 binding HMG_box (PF00505, IPR009071, SM00398): HMG (high mobility group) box |
143 |
LEMD3 | interactor | 4 | 0.833 | 0.222 | LEM (PF03020, IPR003887, SM00540): LEM domain MSC (PF09402, IPR018996): Man1-Src1p-C-terminal domain RBM39linker (PF15519, IPR029123): linker between RRM2 and RRM3 domains in RBM39 protein |
144 |
LRCH1 | interactor | 2 | 1.000 | 0 | CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain LRR_1 (PF00560, IPR001611): Leucine Rich Repeat LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies) LRR_8 (PF13855, IPR001611): Leucine rich repeat JAKMIP_CC3 (PF16034, IPR031994): JAKMIP CC3 domain |
145 |
MAFK | oncoprotein | 8 | 0.786 | 1.908 | bZIP_Maf (PF03131, IPR004826): bZIP Maf transcription factor |
146 |
MAP3K7 | oncoprotein | 17 | 0.217 | 46.900 | Mnd1 (PF03962, IPR005647): Mnd1 family Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase |
147 |
MAPK1 | oncoprotein | 37 | 0.316 | 186.182 | Pkinase (PF00069, IPR000719): Protein kinase domain |
148 |
MAPK8 | oncoprotein | 25 | 0.319 | 84.106 | DUF530 (PF04409, IPR007503): Protein of unknown function (DUF530) Pkinase (PF00069, IPR000719): Protein kinase domain |
149 |
MAX | suppressor | 14 | 0.385 | 20.312 | ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16) HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain SlyX (PF04102, IPR007236): SlyX |
150 |
MCM3AP | interactor | 5 | 0.500 | 3.250 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SAC3_GANP (PF03399, IPR005062): SAC3/GANP family G_path_suppress (PF15991, IPR026094): G-protein pathway suppressor CID_GANP (PF16766, IPR031910): Binding region of GANP to ENY2 NupH_GANP (PF16768, IPR031908): Nucleoporin homology of Germinal-centre associated nuclear protein MCM3AP_GANP (PF16769, IPR031907): MCM3AP domain of GANP |
151 |
MDM4 | oncoprotein | 9 | 0.607 | 3.115 | zf-FLZ (PF04570, IPR007650): zinc-finger of the FCS-type, C2-C2 SWIB (PF02201, IPR003121, SM00151): SWIB/MDM2 domain zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger) |
152 |
MECOM | oncoprotein | 10 | 0.600 | 4.347 | SET (PF00856, IPR001214, SM00317): SET domain zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_6 (PF13912, IPR007087): C2H2-type zinc finger |
153 |
MED15 | interactor | 11 | 0.491 | 11.344 | Med15 (PF09606, IPR019087): ARC105 or Med15 subunit of Mediator complex non-fungal |
154 |
MED24 | interactor | 15 | 0.381 | 21.521 | Med24_N (PF11277, IPR021429): Mediator complex subunit 24 N-terminal |
155 |
MED6 | interactor | 10 | 0.600 | 5.820 | Med6 (PF04934, IPR007018): MED6 mediator sub complex component Peptidase_M15 (PF01427, IPR000755): D-ala-D-ala dipeptidase |
156 |
MEN1 | suppressor | 14 | 0.505 | 11.957 | Menin (PF05053, IPR007747): Menin |
157 |
MEOX2 | interactor | 5 | 0.500 | 5.000 | Homeobox (PF00046, IPR001356, SM00389): Homeobox domain |
158 |
MKL1 | oncoprotein | 6 | 0.600 | 2.092 | RPEL (PF02755, IPR004018, SM00707): RPEL repeat SAP (PF02037, IPR003034, SM00513): SAP domain Troponin-I_N (PF11636, IPR021666): Troponin I residues 1-32 |
159 |
MTF2 | interactor | 3 | 0.667 | 0.333 | PHD (PF00628, IPR019787, SM00249): PHD-finger FYVE_2 (PF02318, IPR010911): FYVE-type zinc finger Mtf2_C (PF14061, IPR025894): Polycomb-like MTF2 factor 2 DUF4537 (PF15057, IPR032770): Domain of unknown function (DUF4537) |
160 |
MYC | oncoprotein | 66 | 0.208 | 815.933 | HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain Myc-LZ (PF02344, IPR003327): Myc leucine zipper domain Myc_N (PF01056, IPR012682): Myc amino-terminal region |
161 |
MYD88 | oncoprotein | 8 | 0.286 | 9.867 | Death (PF00531, IPR000488, SM00005): Death domain TIR (PF01582, IPR000157, SM00255): TIR domain |
162 |
MYOCD | interactor | 7 | 0.619 | 3.154 | BES1_N (PF05687, IPR008540): BES1/BZR1 plant transcription factor, N-terminal IncA (PF04156, IPR007285): IncA protein RPEL (PF02755, IPR004018, SM00707): RPEL repeat SAP (PF02037, IPR003034, SM00513): SAP domain Totivirus_coat (PF05518, IPR008871): Totivirus coat protein |
163 |
NCOA1 | oncoprotein | 26 | 0.493 | 41.575 | DUF1518 (PF07469, IPR010011, SM01151): Domain of unknown function (DUF1518) HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain Nuc_rec_co-act (PF08815, IPR014920): Nuclear receptor coactivator PAS (PF00989, IPR013767, SM00091): PAS fold PAS_3 (PF08447, IPR013655): PAS fold SRC-1 (PF08832, IPR014935): Steroid receptor coactivator PAS_11 (PF14598): PAS domain DUF4927 (PF16279, IPR032565): Domain of unknown function (DUF4927) NCOA_u2 (PF16665): Unstructured region on nuclear receptor coactivator protein |
164 |
NCOA3 | oncoprotein | 26 | 0.422 | 64.010 | DUF1518 (PF07469, IPR010011, SM01151): Domain of unknown function (DUF1518) HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain Nuc_rec_co-act (PF08815, IPR014920): Nuclear receptor coactivator PAS (PF00989, IPR013767, SM00091): PAS fold PAS_3 (PF08447, IPR013655): PAS fold Pex14_N (PF04695, IPR006785): Peroxisomal membrane anchor protein (Pex14p) conserved region SRC-1 (PF08832, IPR014935): Steroid receptor coactivator PAS_11 (PF14598): PAS domain DUF4927 (PF16279, IPR032565): Domain of unknown function (DUF4927) NCOA_u2 (PF16665): Unstructured region on nuclear receptor coactivator protein AIM3 (PF17096, IPR031370): Altered inheritance of mitochondria protein 3 |
165 |
NCOA6 | oncoprotein | 22 | 0.481 | 42.100 | DUF719 (PF05334, IPR007998): Protein of unknown function (DUF719) Fes1 (PF08609, IPR013918): Nucleotide exchange factor Fes1 Presenilin (PF01080, IPR001108): Presenilin DUF3729 (PF12526, IPR022202): Protein of unknown function (DUF3729) Nucleic_acid_bd (PF13820, IPR032715): Putative nucleic acid-binding region NST1 (PF13945, IPR025279): Salt tolerance down-regulator |
166 |
NEDD4 | suppressor | 25 | 0.261 | 89.087 | Rota_NS26 (PF01525, IPR002512): Rotavirus NS26 WW (PF00397, IPR001202, SM00456): WW domain HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase) |
167 |
NEDD4L | suppressor | 12 | 0.364 | 20.457 | WW (PF00397, IPR001202, SM00456): WW domain HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase) |
168 |
NEDD9 | protein found in more fusions | 9 | 0.536 | 5.386 | Serine_rich (PF08824, IPR014928): Serine rich protein interaction domain DUF3513 (PF12026, IPR021901): Domain of unknown function (DUF3513) SH3_9 (PF14604, IPR001452): Variant SH3 domain |
169 |
NF2 | suppressor | 15 | 0.231 | 35.162 | ERM (PF00769, IPR011259): Ezrin/radixin/moesin family FERM_C (PF09380, IPR018980): FERM C-terminal PH-like domain FERM_M (PF00373, IPR019748): FERM central domain FERM_N (PF09379, IPR018979): FERM N-terminal domain |
170 |
NFIA | interactor | 3 | 1.000 | 0 | CTF_NFI (PF00859, IPR000647): CTF/NF-I family transcription modulation region NfI_DNAbd_pre-N (PF10524, IPR019548): Nuclear factor I protein pre-N-terminus MH1 (PF03165, IPR003619, SM00523): MH1 domain |
171 |
NFIC | oncoprotein | 3 | 0.667 | 1.000 | CTF_NFI (PF00859, IPR000647): CTF/NF-I family transcription modulation region NfI_DNAbd_pre-N (PF10524, IPR019548): Nuclear factor I protein pre-N-terminus MH1 (PF03165, IPR003619, SM00523): MH1 domain |
172 |
NFYC | interactor | 8 | 0.714 | 1.961 | CBFD_NFYB_HMF (PF00808, IPR003958): Histone-like transcription factor (CBF/NF-Y) and archaeal histone E1-E2_ATPase (PF00122, IPR008250): E1-E2 ATPase Fucose_iso_C (PF02952, IPR015888): L-fucose isomerase, C-terminal domain |
173 |
NOTCH1 | suppressor | 39 | 0.161 | 306.174 | Ank (PF00023, IPR002110, SM00248): Ankyrin repeat EGF (PF00008, IPR000742, SM00181): EGF-like domain EGF_2 (PF07974, IPR013111): EGF-like domain EGF_alliinase (PF04863, IPR006947): Alliinase EGF-like domain EGF_CA (PF07645, IPR001881, SM00179): Calcium-binding EGF domain NOD (PF06816, IPR010660): NOTCH protein NODP (PF07684, IPR011656): NOTCH protein TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit Notch (PF00066, IPR000800, SM00004): LNR domain DUF3454 (PF11936, IPR024600): Domain of unknown function (DUF3454) hEGF (PF12661, IPR013032): Human growth factor-like EGF cEGF (PF12662, IPR026823): Complement Clr-like EGF-like Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) |
174 |
NOTCH4 | oncoprotein | 4 | 0.833 | 0.065 | EGF (PF00008, IPR000742, SM00181): EGF-like domain EGF_2 (PF07974, IPR013111): EGF-like domain EGF_alliinase (PF04863, IPR006947): Alliinase EGF-like domain EGF_CA (PF07645, IPR001881, SM00179): Calcium-binding EGF domain Lem_TRP (PF08262, IPR013206): Leucophaea maderae tachykinin-related peptide NOD (PF06816, IPR010660): NOTCH protein NODP (PF07684, IPR011656): NOTCH protein Notch (PF00066, IPR000800, SM00004): LNR domain hEGF (PF12661, IPR013032): Human growth factor-like EGF cEGF (PF12662, IPR026823): Complement Clr-like EGF-like Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_5 (PF13857): Ankyrin repeats (many copies) FXa_inhibition (PF14670): Coagulation Factor Xa inhibitory site |
175 |
NR3C1 | protein found in more fusions | 29 | 0.339 | 103.801 | GCR (PF02155, IPR001409): Glucocorticoid receptor zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor |
176 |
NR4A1 | suppressor | 17 | 0.478 | 21.231 | zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor |
177 |
NUP153 | protein found in more fusions | 12 | 0.418 | 14.297 | Nup153 (PF08604, IPR013913): Nucleoporin Nup153-like Nup_retrotrp_bd (PF10599, IPR018892): Retro-transposon transporting motif zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others Nucleoporin_FG (PF13634, IPR025574): Nucleoporin FG repeat region |
178 |
NUP214 | oncoprotein | 9 | 0.536 | 4.231 | dCache_2 (PF08269, IPR004010, SM01049): Cache domain HisKA (PF00512, IPR003661, SM00388): His Kinase A (phospho-acceptor) domain MIP-T3 (PF10243): Microtubule-binding protein MIP-T3 ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_FG (PF13634, IPR025574): Nucleoporin FG repeat region Mustang (PF15682, IPR031394): Musculoskeletal, temporally activated-embryonic nuclear protein 1 NUP214 (PF16755): Nucleoporin or Nuclear pore complex subunit NUP214=Nup159 |
179 |
OPA1 | interactor | 4 | 0.833 | 0.069 | DUF1593 (PF07632, IPR011483): Protein of unknown function (DUF1593) Ephrin_rec_like (PF07699, IPR011641): Putative ephrin-receptor like IncA (PF04156, IPR007285): IncA protein Ras (PF00071, IPR001806, SM00173): Ras family Dynamin_N (PF00350, IPR001401, SM00053): Dynamin family DUF4061 (PF13270, IPR025271): Domain of unknown function (DUF4061) |
180 |
OTUB1 | interactor | 20 | 0.289 | 76.184 | Peptidase_C65 (PF10275, IPR019400): Peptidase C65 Otubain |
181 |
PABPC1 | oncoprotein | 23 | 0.312 | 91.310 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP (PF00658, IPR002004, SM00517): Poly-adenylate binding protein, unique domain YflT (PF11181, IPR025889): Heat induced stress protein YflT |
182 |
PAPPA | interactor | 5 | 0.600 | 1.889 | Peptidase_M43 (PF05572, IPR008754): Pregnancy-associated plasma protein-A Sushi (PF00084, IPR000436, SM00032): Sushi repeat (SCR repeat) Notch (PF00066, IPR000800, SM00004): LNR domain Laminin_G_3 (PF13385): Concanavalin A-like lectin/glucanases superfamily DUF4215 (PF13948, IPR011936): Domain of unknown function (DUF4215) |
183 |
PARD3 | interactor | 8 | 0.679 | 3.314 | PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) DUF3534 (PF12053, IPR021922): Domain of unknown function (DUF3534) PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term |
184 |
PARP4 | interactor | 1 | 0 | 0 | BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain PARP (PF00644, IPR012317): Poly(ADP-ribose) polymerase catalytic domain PARP_reg (PF02877, IPR004102): Poly(ADP-ribose) polymerase, regulatory domain VIT (PF08487, IPR013694, SM00609): Vault protein inter-alpha-trypsin domain VWA (PF00092, IPR002035, SM00327): von Willebrand factor type A domain |
185 |
PAX6 | suppressor | 12 | 0.455 | 17.530 | PAX (PF00292, IPR001523, SM00351): 'Paired box' domain Homeobox (PF00046, IPR001356, SM00389): Homeobox domain |
186 |
PCDH1 | interactor | 1 | 0 | 0 | Cadherin_2 (PF08266, IPR013164): Cadherin-like Protocadherin (PF08374, IPR013585): Protocadherin Cadherin (PF00028, IPR002126, SM00112): Cadherin domain RGCC (PF15151, IPR029252): Response gene to complement 32 protein family Cadherin_3 (PF16184): Cadherin-like |
187 |
PCK2 | interactor | 3 | 0.667 | 0.111 | PEPCK (PF00821, IPR008209): Phosphoenolpyruvate carboxykinase |
188 |
PHC2 | interactor | 3 | 1.000 | 0 | SAM_1 (PF00536, IPR021129, SM00454): SAM domain (Sterile alpha motif) TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit zf-CGNR (PF11706, IPR021005): CGNR zinc finger DUF4692 (PF15763, IPR031517): Domain of unknown function (DUF4692) PHC2_SAM_assoc (PF16616): Unstructured region on Polyhomeotic-like protein 1 and 2 |
189 |
PIAS2 | protein found in more fusions | 17 | 0.358 | 34.130 | SAP (PF02037, IPR003034, SM00513): SAP domain zf-MIZ (PF02891, IPR004181): MIZ/SP-RING zinc finger PINIT (PF14324, IPR023321): PINIT domain |
190 |
PIAS3 | oncoprotein | 12 | 0.500 | 11.793 | SAP (PF02037, IPR003034, SM00513): SAP domain zf-MIZ (PF02891, IPR004181): MIZ/SP-RING zinc finger PINIT (PF14324, IPR023321): PINIT domain |
191 |
PIAS4 | interactor | 20 | 0.384 | 54.291 | CENP-B_dimeris (PF09026, IPR015115): Centromere protein B dimerisation domain SAP (PF02037, IPR003034, SM00513): SAP domain zf-MIZ (PF02891, IPR004181): MIZ/SP-RING zinc finger PINIT (PF14324, IPR023321): PINIT domain |
192 |
PIK3CA | oncoprotein | 12 | 0.470 | 14.968 | PI3K_C2 (PF00792, IPR002420, SM00142): Phosphoinositide 3-kinase C2 PI3K_p85B (PF02192, IPR003113, SM00143): PI3-kinase family, p85-binding domain PI3K_rbd (PF00794, IPR000341, SM00144): PI3-kinase family, ras-binding domain PI3Ka (PF00613, IPR001263, SM00145): Phosphoinositide 3-kinase family, accessory domain (PIK domain) DUF2321 (PF10083, IPR016891): Uncharacterized protein conserved in bacteria (DUF2321) PI3_PI4_kinase (PF00454, IPR000403, SM00146): Phosphatidylinositol 3- and 4-kinase |
193 |
PIN1 | suppressor | 35 | 0.240 | 273.976 | Rotamase (PF00639, IPR000297): PPIC-type PPIASE domain WW (PF00397, IPR001202, SM00456): WW domain |
194 |
PITX1 | oncoprotein | 3 | 0.667 | 0.667 | Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region OAR (PF03826, IPR003654): OAR domain Homeobox (PF00046, IPR001356, SM00389): Homeobox domain |
195 |
PITX2 | interactor | 5 | 1.000 | 0 | OAR (PF03826, IPR003654): OAR domain XRCC4 (PF06632, IPR010585): DNA double-strand break repair and V(D)J recombination protein XRCC4 Homeobox (PF00046, IPR001356, SM00389): Homeobox domain |
196 |
PJA1 | interactor | 7 | 0.333 | 5.519 | zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain |
197 |
PLAG1 | oncoprotein | 3 | 1.000 | 0 | zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_4 (PF13894): C2H2-type zinc finger zf-C2H2_6 (PF13912, IPR007087): C2H2-type zinc finger |
198 |
PLAGL1 | suppressor | 8 | 0.750 | 1.096 | zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_4 (PF13894): C2H2-type zinc finger zf-C2H2_6 (PF13912, IPR007087): C2H2-type zinc finger |
199 |
PLG | interactor | 6 | 0.600 | 3.165 | Kringle (PF00051, IPR000001): Kringle domain PAN_1 (PF00024, IPR003014): PAN domain Trypsin (PF00089, IPR001254, SM00020): Trypsin |
200 |
PML | suppressor | 44 | 0.246 | 300.194 | zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger DUF3583 (PF12126, IPR021978): Protein of unknown function (DUF3583) zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger) |
201 |
PPARG | suppressor | 33 | 0.351 | 118.755 | zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor PPARgamma_N (PF12577, IPR022590): PPAR gamma N-terminal region |
202 |
PPP1R12C | interactor | 2 | 0 | 0 | MSA-2c (PF12238, IPR021060): Merozoite surface antigen 2c Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_5 (PF13857): Ankyrin repeats (many copies) DUF4695 (PF15766, IPR031521): Domain of unknown function (DUF4695) PRKG1_interact (PF15898, IPR031775): cGMP-dependent protein kinase interacting domain |
203 |
PPP2R1A | oncoprotein | 18 | 0.320 | 46.339 | TAF6_C (PF07571, IPR011442): TAF6 C-terminal HEAT repeat domain HEAT (PF02985, IPR000357): HEAT repeat HEAT_PBS (PF03130, IPR004155, SM00567): PBS lyase HEAT-like repeat HEAT_2 (PF13646): HEAT repeats |
204 |
PRDM16 | oncoprotein | 3 | 1.000 | 0 | SET (PF00856, IPR001214, SM00317): SET domain zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_6 (PF13912, IPR007087): C2H2-type zinc finger |
205 |
PRDM4 | suppressor | 4 | 0.667 | 0.400 | zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type Ecl1 (PF12855, IPR024368): Life-span regulatory factor zf-met (PF12874): Zinc-finger of C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain |
206 |
PROX1 | suppressor | 6 | 0.400 | 7.043 | GET2 (PF08690, IPR028143): GET complex subunit GET2 NifQ (PF04891, IPR006975): NifQ HPD (PF05044, IPR023082): Homeo-prospero domain PP_kinase_N (PF13089, IPR025198): Polyphosphate kinase N-terminal domain Metal_resist (PF13801, IPR025961): Heavy-metal resistance |
207 |
PRTN3 | interactor | 1 | 0 | 0 | Trypsin (PF00089, IPR001254, SM00020): Trypsin |
208 |
PSMD11 | interactor | 14 | 0.418 | 19.174 | DUF247 (PF03140, IPR004158): Plant protein of unknown function PCI (PF01399, IPR000717, SM00088): PCI domain AAA_16 (PF13191): AAA ATPase domain TPR_12 (PF13424): Tetratricopeptide repeat |
209 |
PSPC1 | interactor | 6 | 0.533 | 3.876 | FUSC (PF04632, IPR006726): Fusaric acid resistance protein family NOPS (PF08075, IPR012975): NOPS (NUC059) domain RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Zot (PF05707, IPR008900): Zonular occludens toxin (Zot) |
210 |
PTPN6 | suppressor | 4 | 0.667 | 1.667 | SH2 (PF00017, IPR000980, SM00252): SH2 domain Y_phosphatase (PF00102, IPR000242, SM00194): Protein-tyrosine phosphatase PolyA_pol_arg_C (PF12626, IPR025866): Polymerase A arginine-rich C-terminus |
211 |
RAB11FIP5 | interactor | 3 | 1.000 | 0 | C2 (PF00168, IPR000008, SM00239): C2 domain Herpes_PAP (PF03325, IPR004997): Herpesvirus polymerase accessory protein K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain RBD-FIP (PF09457, IPR019018): FIP domain |
212 |
RANBP9 | suppressor | 15 | 0.407 | 16.236 | Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator LisH (PF08513, IPR013720, SM00667): LisH SPRY (PF00622, IPR003877, SM00449): SPRY domain CLTH (PF10607, IPR024964): CTLH/CRA C-terminal to LisH motif domain |
213 |
RBL1 | suppressor | 17 | 0.382 | 33.709 | RB_A (PF01858, IPR002720): Retinoblastoma-associated protein A domain RB_B (PF01857, IPR002719): Retinoblastoma-associated protein B domain Rb_C (PF08934, IPR015030): Rb C-terminal domain DUF3452 (PF11934, IPR024599): Domain of unknown function (DUF3452) |
214 |
RBX1 | oncoprotein | 12 | 0.364 | 11.872 | zf-rbx1 (PF12678, IPR024766): RING-H2 zinc finger domain |
215 |
RCVRN | interactor | 2 | 1.000 | 0 | CytochromB561_N (PF09786, IPR019176): Cytochrome B561, N terminal |
216 |
RELA | oncoprotein | 50 | 0.242 | 471.641 | DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region RHD_DNA_bind (PF00554, IPR011539): Rel homology DNA-binding domain RHD_dimer (PF16179, IPR032397): Rel homology dimerisation domain |
217 |
RGCC | interactor | 3 | 1.000 | 0 | RGCC (PF15151, IPR029252): Response gene to complement 32 protein family |
218 |
RIOK2 | interactor | 3 | 0.667 | 0.143 | RIO1 (PF01163, IPR018934): RIO1 family Rio2_N (PF09202, IPR015285): Rio2, N-terminal |
219 |
RNF111 | suppressor | 10 | 0.583 | 5.117 | zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain Prok-RING_1 (PF14446): Prokaryotic RING finger family 1 RNF111_N (PF15303, IPR029306): E3 ubiquitin-protein ligase Arkadia N-terminus |
220 |
RNF31 | interactor | 6 | 0.400 | 4.500 | Auto_anti-p27 (PF06677, IPR009563): Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) IBR (PF01485, IPR002867, SM00647): IBR domain, a half RING-finger domain PUB (PF09409, IPR018997): PUB domain TF_Zn_Ribbon (PF08271, IPR013137): TFIIB zinc-binding zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others zf-RING_4 (PF14570): RING/Ubox like zinc-binding domain HOIP-UBA (PF16678, IPR032065): UB-associated-like domain of HOIP or E3 ubiquitin-protein ligase |
221 |
RPA1 | suppressor | 23 | 0.342 | 72.989 | Rep-A_N (PF04057, IPR007199): Replication factor-A protein 1, N-terminal domain Rep_fac-A_C (PF08646, IPR013955): Replication factor-A C terminal domain tRNA_anti-codon (PF01336, IPR004365): OB-fold nucleic acid binding domain REPA_OB_2 (PF16900, IPR031657): Replication protein A OB domain |
222 |
RPL3 | interactor | 12 | 0.636 | 7.244 | Ribosomal_L3 (PF00297, IPR000597): Ribosomal protein L3 |
223 |
RPL4 | interactor | 11 | 0.655 | 5.767 | Ribosomal_L4 (PF00573, IPR002136): Ribosomal protein L4/L1 family Ribos_L4_asso_C (PF14374, IPR025755): 60S ribosomal protein L4 C-terminal domain |
224 |
RPLP0 | interactor | 12 | 0.667 | 5.884 | Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein Ribosomal_L10 (PF00466, IPR001790): Ribosomal protein L10 |
225 |
RPSAP15 | interactor | 2 | 1.000 | 0 | NA |
226 |
RUNX1 | suppressor | 26 | 0.387 | 64.188 | Runt (PF00853, IPR013524): Runt domain RunxI (PF08504, IPR013711): Runx inhibition domain DUF3037 (PF11236, IPR021398): Protein of unknown function (DUF3037) |
227 |
RUNX2 | suppressor | 25 | 0.380 | 63.136 | DUF1180 (PF06679, IPR009565): Protein of unknown function (DUF1180) Runt (PF00853, IPR013524): Runt domain TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360) DUF2722 (PF10846, IPR021216): Protein of unknown function (DUF2722) |
228 |
RUNX3 | suppressor | 14 | 0.516 | 11.154 | Runt (PF00853, IPR013524): Runt domain RunxI (PF08504, IPR013711): Runx inhibition domain |
229 |
S100A4 | interactor | 5 | 0.700 | 0.750 | S_100 (PF01023, IPR013787): S-100/ICaBP type calcium binding domain EF-hand_4 (PF12763, IPR000261): Cytoskeletal-regulatory complex EF hand EF-hand_7 (PF13499, IPR011992): EF-hand domain pair |
230 |
SAP130 | interactor | 7 | 0.714 | 2.114 | SAP130_C (PF16014, IPR031963): Histone deacetylase complex subunit SAP130 C-terminus |
231 |
SERTAD1 | interactor | 11 | 0.255 | 27.494 | CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal SERTA (PF06031, IPR009263): SERTA motif |
232 |
SETD2 | suppressor | 3 | 1.000 | 0 | DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777) SET (PF00856, IPR001214, SM00317): SET domain SRI (PF08236, IPR013257): SRI (Set2 Rpb1 interacting) domain Med26 (PF08711, IPR017923): TFIIS helical bundle-like domain WW (PF00397, IPR001202, SM00456): WW domain DUF3592 (PF12158, IPR021994): Protein of unknown function (DUF3592) |
233 |
SH2D2A | interactor | 2 | 1.000 | 0 | SH2 (PF00017, IPR000980, SM00252): SH2 domain |
234 |
SIK3 | oncoprotein | 4 | 0.500 | 0.784 | GET2 (PF08690, IPR028143): GET complex subunit GET2 Pkinase (PF00069, IPR000719): Protein kinase domain Jnk-SapK_ap_N (PF09744, IPR019143): JNK_SAPK-associated protein-1 |
235 |
SIN3A | oncoprotein | 27 | 0.311 | 122.706 | Sin3_corepress (PF08295, IPR013194, SM00761): Sin3 family co-repressor PAH (PF02671, IPR003822, SM00309): Paired amphipathic helix repeat Sin3a_C (PF16879, IPR031693): C-terminal domain of Sin3a protein |
236 |
SKI | oncoprotein | 29 | 0.278 | 134.212 | c-SKI_SMAD_bind (PF08782, IPR014890, SM01046): c-SKI Smad4 binding domain Ski_Sno (PF02437, IPR003380): SKI/SNO/DAC family SlyX (PF04102, IPR007236): SlyX HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1 |
237 |
SKIL | suppressor | 32 | 0.194 | 244.312 | c-SKI_SMAD_bind (PF08782, IPR014890, SM01046): c-SKI Smad4 binding domain DUF489 (PF04356, IPR007451): Protein of unknown function (DUF489) DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972) Neur_chan_memb (PF02932, IPR006029): Neurotransmitter-gated ion-channel transmembrane region Ski_Sno (PF02437, IPR003380): SKI/SNO/DAC family DUF2115 (PF09888, IPR019215): Uncharacterized protein conserved in archaea (DUF2115) |
238 |
SLC25A12 | interactor | 5 | 0.400 | 2.921 | Mito_carr (PF00153, IPR018108): Mitochondrial carrier protein EF-hand_1 (PF00036, IPR002048, SM00054): EF hand EF-hand_6 (PF13405, IPR002048): EF-hand domain EF-hand_7 (PF13499, IPR011992): EF-hand domain pair EF-hand_8 (PF13833, IPR002048): EF-hand domain pair |
239 |
SLC9A3R2 | interactor | 4 | 0.500 | 2.500 | EBP50_C (PF09007, IPR015098): EBP50, C-terminal GRASP55_65 (PF04495, IPR024958): GRASP55/65 PDZ-like domain PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) |
240 |
SMAD1 | interactor | 59 | 0.181 | 703.609 | MH1 (PF03165, IPR003619, SM00523): MH1 domain MH2 (PF03166, IPR001132, SM00524): MH2 domain |
241 |
SMAD2 | suppressor | 139 | 0.084 | 6244.816 | MH1 (PF03165, IPR003619, SM00523): MH1 domain MH2 (PF03166, IPR001132, SM00524): MH2 domain |
242 |
SMAD4 | suppressor | 79 | 0.140 | 1503.574 | MH1 (PF03165, IPR003619, SM00523): MH1 domain MH2 (PF03166, IPR001132, SM00524): MH2 domain |
243 |
SMAD5 | interactor | 27 | 0.313 | 101.200 | MH1 (PF03165, IPR003619, SM00523): MH1 domain MH2 (PF03166, IPR001132, SM00524): MH2 domain |
244 |
SMAD7 | interactor | 41 | 0.217 | 345.841 | MH1 (PF03165, IPR003619, SM00523): MH1 domain MH2 (PF03166, IPR001132, SM00524): MH2 domain |
245 |
SMAD9 | interactor | 27 | 0.160 | 202.623 | MH1 (PF03165, IPR003619, SM00523): MH1 domain MH2 (PF03166, IPR001132, SM00524): MH2 domain |
246 |
SMARCA4 | suppressor | 38 | 0.326 | 186.880 | DUF1840 (PF08895, IPR014991): Domain of unknown function (DUF1840) HSA (PF07529, IPR014012, SM00573): HSA QLQ (PF08880, IPR014978, SM00951): QLQ SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain BRK (PF07533, IPR006576, SM00592): BRK domain Bromodomain (PF00439, IPR001487, SM00297): Bromodomain Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal DUF4065 (PF13274, IPR025272): Protein of unknown function (DUF4065) SnAC (PF14619, IPR029295): Snf2-ATP coupling, chromatin remodelling complex WRNPLPNID (PF15017): Putative WW-binding domain and destruction box |
247 |
SMARCC1 | suppressor | 27 | 0.428 | 52.240 | SWIRM (PF04433, IPR007526): SWIRM domain Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain DUF2618 (PF10940, IPR021237): Protein of unknown function (DUF2618) PTPRCAP (PF15713, IPR016553): Protein tyrosine phosphatase receptor type C-associated SWIRM-assoc_1 (PF16495, IPR032451): SWIRM-associated region 1 SWIRM-assoc_2 (PF16496, IPR032450): SWIRM-associated domain at the N-terminal SWIRM-assoc_3 (PF16498, IPR032448): SWIRM-associated domain at the C-terminal |
248 |
SMARCC2 | interactor | 19 | 0.421 | 30.745 | GHMP_kinases_N (PF00288, IPR006204): GHMP kinases N terminal domain SWIRM (PF04433, IPR007526): SWIRM domain DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360) Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain SWIRM-assoc_1 (PF16495, IPR032451): SWIRM-associated region 1 SWIRM-assoc_2 (PF16496, IPR032450): SWIRM-associated domain at the N-terminal SWIRM-assoc_3 (PF16498, IPR032448): SWIRM-associated domain at the C-terminal |
249 |
SMURF1 | interactor | 35 | 0.230 | 237.516 | C2 (PF00168, IPR000008, SM00239): C2 domain WW (PF00397, IPR001202, SM00456): WW domain HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase) |
250 |
SMURF2 | protein found in more fusions | 24 | 0.379 | 61.859 | C2 (PF00168, IPR000008, SM00239): C2 domain WW (PF00397, IPR001202, SM00456): WW domain HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase) |
251 |
SNRNP70 | interactor | 17 | 0.463 | 23.253 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MIP-T3 (PF10243): Microtubule-binding protein MIP-T3 U1snRNP70_N (PF12220, IPR022023): U1 small nuclear ribonucleoprotein of 70kDa MW N terminal |
252 |
SNW1 | protein found in more fusions | 41 | 0.209 | 334.929 | SKIP_SNW (PF02731, IPR004015): SKIP/SNW domain PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term SIR4_SID (PF16991, IPR031556): Sir4 SID domain |
253 |
SOX9 | oncoprotein | 6 | 0.800 | 0.403 | Pex14_N (PF04695, IPR006785): Peroxisomal membrane anchor protein (Pex14p) conserved region TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit HMG_box (PF00505, IPR009071, SM00398): HMG (high mobility group) box Sox_N (PF12444, IPR022151): Sox developmental protein N terminal |
254 |
SP1 | protein found in more fusions | 47 | 0.314 | 307.462 | zf-Di19 (PF05605, IPR008598): Drought induced 19 protein (Di19), zinc-binding Herpes_capsid (PF06112, IPR009299): Gammaherpesvirus capsid protein zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type Miga (PF10265, IPR019392): Mitoguardin zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 |
255 |
SPTBN1 | suppressor | 17 | 0.324 | 45.703 | CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain COG2 (PF06148, IPR024602): COG (conserved oligomeric Golgi) complex component, COG2 DUF1764 (PF08576, IPR013885): Eukaryotic protein of unknown function (DUF1764) Spectrin (PF00435, IPR002017): Spectrin repeat PH_9 (PF15410): Pleckstrin homology domain |
256 |
SQRDL | interactor | 5 | 0.600 | 0.777 | Pyr_redox_2 (PF07992, IPR023753): Pyridine nucleotide-disulphide oxidoreductase |
257 |
SQSTM1 | oncoprotein | 20 | 0.287 | 72.199 | PB1 (PF00564, IPR000270, SM00666): PB1 domain ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type UBA_5 (PF16577, IPR015940): UBA domain |
258 |
SREBF2 | protein found in more fusions | 14 | 0.308 | 24.752 | HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit |
259 |
SRY | interactor | 5 | 0.700 | 0.736 | DUF1908 (PF08926, IPR015022): Domain of unknown function (DUF1908) HMG_box (PF00505, IPR009071, SM00398): HMG (high mobility group) box |
260 |
SS18L1 | oncoprotein | 10 | 0.444 | 5.465 | DUF1313 (PF07011, IPR009741): Protein of unknown function (DUF1313) SSXT (PF05030, IPR007726): SSXT protein (N-terminal region) |
261 |
ST6GALNAC2 | interactor | 1 | 0 | 0 | Glyco_transf_29 (PF00777, IPR001675): Glycosyltransferase family 29 (sialyltransferase) |
262 |
STRAP | protein found in more fusions | 10 | 0.611 | 3.337 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain |
263 |
STUB1 | suppressor | 31 | 0.292 | 134.577 | U-box (PF04564, IPR003613, SM00504): U-box domain ANAPC3 (PF12895): Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 (PF13414, IPR011990): TPR repeat TPR_20 (PF14561): Tetratricopeptide repeat |
264 |
SUV39H1 | protein found in more fusions | 17 | 0.358 | 36.380 | Chromo (PF00385, IPR023780, SM00298): Chromo (CHRromatin Organisation MOdifier) domain Pre-SET (PF05033, IPR007728): Pre-SET motif SET (PF00856, IPR001214, SM00317): SET domain |
265 |
SVEP1 | interactor | 4 | 0.500 | 1.389 | EGF (PF00008, IPR000742, SM00181): EGF-like domain EGF_2 (PF07974, IPR013111): EGF-like domain EGF_CA (PF07645, IPR001881, SM00179): Calcium-binding EGF domain Ephrin_rec_like (PF07699, IPR011641): Putative ephrin-receptor like HYR (PF02494, IPR003410): HYR domain VWA (PF00092, IPR002035, SM00327): von Willebrand factor type A domain Sushi (PF00084, IPR000436, SM00032): Sushi repeat (SCR repeat) Pentaxin (PF00354, IPR001759, SM00159): Pentaxin family VERL (PF11386, IPR021526): Vitelline envelope receptor for lysin hEGF (PF12661, IPR013032): Human growth factor-like EGF cEGF (PF12662, IPR026823): Complement Clr-like EGF-like |
266 |
TANK | suppressor | 7 | 0.400 | 6.452 | DUF3713 (PF12506, IPR022186): Protein of unknown function (DUF3713) TBD (PF12845, IPR024581): TBD domain |
267 |
TCF12 | oncoprotein | 10 | 0.639 | 5.347 | HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain |
268 |
TCP1 | interactor | 16 | 0.400 | 25.591 | Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family |
269 |
TDP2 | interactor | 4 | 0.500 | 1.500 | Exo_endo_phos (PF03372, IPR005135): Endonuclease/Exonuclease/phosphatase family DUF4150 (PF13665, IPR025425): Domain of unknown function (DUF4150) UBA_4 (PF14555): UBA-like domain |
270 |
TEKT4 | interactor | 1 | 0 | 0 | Tektin (PF03148, IPR000435): Tektin family |
271 |
TF | interactor | 3 | 1.000 | 0 | Transferrin (PF00405, IPR001156, SM00094): Transferrin |
272 |
TFE3 | oncoprotein | 3 | 1.000 | 0 | HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain DUF3371 (PF11851, IPR021802): Domain of unknown function (DUF3371) MITF_TFEB_C_3_N (PF15951, IPR031867): MITF/TFEB/TFEC/TFE3 N-terminus |
273 |
TGFB1I1 | interactor | 7 | 0.476 | 5.552 | LIM (PF00412, IPR001781, SM00132): LIM domain Paxillin (PF03535): Paxillin family |
274 |
TGFBR1 | oncoprotein | 19 | 0.386 | 39.660 | Activin_recp (PF01064, IPR000472): Activin types I and II receptor domain Pkinase (PF00069, IPR000719): Protein kinase domain TGF_beta_GS (PF08515, IPR003605, SM00467): Transforming growth factor beta type I GS-motif |
275 |
TGIF1 | oncoprotein | 10 | 0.578 | 7.050 | Homeobox_KN (PF05920, IPR008422): Homeobox KN domain LRS4 (PF10422, IPR018479): Monopolin complex subunit LRS4 |
276 |
TGIF2 | interactor | 2 | 1.000 | 0 | Homeobox_KN (PF05920, IPR008422): Homeobox KN domain |
277 |
TGM2 | protein found in more fusions | 11 | 0.311 | 21.423 | Transglut_C (PF00927, IPR008958): Transglutaminase family, C-terminal ig like domain Transglut_N (PF00868, IPR001102): Transglutaminase family Transglut_core (PF01841, IPR002931, SM00460): Transglutaminase-like superfamily |
278 |
TLR4 | interactor | 6 | 0.400 | 5.750 | LRR_1 (PF00560, IPR001611): Leucine Rich Repeat TIR (PF01582, IPR000157, SM00255): TIR domain LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies) LRR_8 (PF13855, IPR001611): Leucine rich repeat LRR_9 (PF14580): Leucine-rich repeat |
279 |
TMED1 | interactor | 2 | 1.000 | 0 | EMP24_GP25L (PF01105, IPR009038): emp24/gp25L/p24 family/GOLD |
280 |
TOB1 | interactor | 9 | 0.444 | 7.288 | PAM2 (PF07145, IPR009818): Ataxin-2 C-terminal region BTG (PF07742, IPR002087, SM00099): BTG family PRIMA1 (PF16101): Proline-rich membrane anchor 1 |
281 |
TP53 | suppressor | 95 | 0.166 | 1865.131 | DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region P53 (PF00870, IPR011615): P53 DNA-binding domain P53_tetramer (PF07710, IPR010991): P53 tetramerisation motif |
282 |
TP63 | suppressor | 21 | 0.337 | 59.608 | Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region P53 (PF00870, IPR011615): P53 DNA-binding domain P53_tetramer (PF07710, IPR010991): P53 tetramerisation motif SAM_2 (PF07647, IPR011510): SAM domain (Sterile alpha motif) |
283 |
TRIB3 | interactor | 8 | 0.393 | 8.686 | Pkinase (PF00069, IPR000719): Protein kinase domain |
284 |
TRIM33 | oncoprotein | 13 | 0.439 | 13.710 | PHD (PF00628, IPR019787, SM00249): PHD-finger Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein Siva (PF05458, IPR022773): Cd27 binding protein (Siva) Spectrin (PF00435, IPR002017): Spectrin repeat TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger Bromodomain (PF00439, IPR001487, SM00297): Bromodomain zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger |
285 |
TRIM62 | suppressor | 3 | 1.000 | 0 | Laminin_II (PF06009, IPR010307): Laminin Domain II Ribosomal_L37ae (PF01780, IPR002674): Ribosomal L37ae protein family SPRY (PF00622, IPR003877, SM00449): SPRY domain zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger PRY (PF13765, IPR006574, SM00589): SPRY-associated domain DUF3416 (PF11896, IPR021828): Domain of unknown function (DUF3416) Snapin_Pallidin (PF14712, IPR028119): Snapin/Pallidin zf-C3HC4_4 (PF15227): zinc finger of C3HC4-type, RING |
286 |
TSC2 | suppressor | 8 | 0.607 | 2.132 | Rap_GAP (PF02145, IPR000331): Rap/ran-GAP Tuberin (PF03542, IPR018515): Tuberin DUF3384 (PF11864, IPR024584): Domain of unknown function (DUF3384) Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1 |
287 |
TSC22D4 | interactor | 8 | 0.357 | 13.515 | AflR (PF08493, IPR013700): Aflatoxin regulatory protein TSC22 (PF01166, IPR000580): TSC-22/dip/bun family |
288 |
U2AF2 | protein found in more fusions | 20 | 0.327 | 64.413 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Transformer (PF06495, IPR010519): Fruit fly transformer protein |
289 |
UBQLN4 | interactor | 7 | 0.467 | 5.300 | CRF (PF00473, IPR000187, SM00039): Corticotropin-releasing factor family DUF1180 (PF06679, IPR009565): Protein of unknown function (DUF1180) Arm_2 (PF04826, IPR006911): Armadillo-like NUDE_C (PF04880, IPR006964): NUDE protein, C-terminal conserved region UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain XPC-binding (PF09280, IPR015360): XPC-binding domain ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family Fur_reg_FbpB (PF13040, IPR025004): Fur-regulated basic protein B partial_CstF (PF15861, IPR031721): Partial cleavage stimulation factor domain |
290 |
UCHL5 | oncoprotein | 11 | 0.378 | 16.799 | Peptidase_C12 (PF01088, IPR001578): Ubiquitin carboxyl-terminal hydrolase, family 1 |
291 |
USP15 | oncoprotein | 16 | 0.514 | 17.237 | UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase DUSP (PF06337, IPR006615, SM00695): DUSP domain Ubiquitin_3 (PF14836, IPR028135): Ubiquitin-like domain |
292 |
USP7 | oncoprotein | 23 | 0.190 | 118.329 | MATH (PF00917, IPR002083, SM00061): MATH domain UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase USP7_ICP0_bdg (PF12436, IPR024729): ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 (PF14533, IPR029346): Ubiquitin-specific protease C-terminal |
293 |
USP9X | interactor | 11 | 0.436 | 12.873 | DUF1722 (PF08349, IPR013560): Protein of unknown function (DUF1722) UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase Utp13 (PF08625, IPR013934): Utp13 specific WD40 associated domain |
294 |
VAV2 | oncoprotein | 3 | 0.667 | 0.400 | PH (PF00169, IPR001849, SM00233): PH domain RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_2 (PF07653, IPR011511): Variant SH3 domain C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain) CAMSAP_CH (PF11971, IPR022613): CAMSAP CH domain CotJB (PF12652, IPR024207): CotJB protein |
295 |
VDR | suppressor | 27 | 0.363 | 89.215 | zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor |
296 |
WWP1 | oncoprotein | 15 | 0.429 | 15.549 | C2 (PF00168, IPR000008, SM00239): C2 domain WW (PF00397, IPR001202, SM00456): WW domain HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase) |
297 |
WWP2 | interactor | 10 | 0.417 | 9.085 | WW (PF00397, IPR001202, SM00456): WW domain HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase) |
298 |
XPO6 | interactor | 4 | 0.667 | 0.583 | IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain Xpo1 (PF08389, IPR013598): Exportin 1-like protein |
299 |
XRCC6 | oncoprotein | 29 | 0.336 | 85.443 | Ku (PF02735, IPR006164, SM00559): Ku70/Ku80 beta-barrel domain Ku_C (PF03730, IPR005160): Ku70/Ku80 C-terminal arm Ku_N (PF03731, IPR005161): Ku70/Ku80 N-terminal alpha/beta domain SAP (PF02037, IPR003034, SM00513): SAP domain |
300 |
YAP1 | suppressor | 22 | 0.260 | 78.123 | Bindin (PF02084, IPR000775): Bindin WW (PF00397, IPR001202, SM00456): WW domain GspL_C (PF12693, IPR025691): GspL periplasmic domain FAM181 (PF15238, IPR029359): FAM181 |
301 |
YTHDF2 | interactor | 6 | 0.400 | 3.581 | YTH (PF04146, IPR007275): YT521-B-like domain DUF4106 (PF13388, IPR025179): Protein of unknown function (DUF4106) |
302 |
YY1 | protein found in more fusions | 30 | 0.310 | 121.850 | zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_4 (PF13894): C2H2-type zinc finger Keratin_2_tail (PF16210, IPR032449): Keratin type II cytoskeletal 1 tail |
303 |
ZBTB16 | suppressor | 20 | 0.415 | 40.371 | BTB (PF00651, IPR013069, SM00225): BTB/POZ domain zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_4 (PF13894): C2H2-type zinc finger zf-C2H2_6 (PF13912, IPR007087): C2H2-type zinc finger |
304 |
ZBTB3 | interactor | 8 | 0.286 | 14.571 | BTB (PF00651, IPR013069, SM00225): BTB/POZ domain zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_4 (PF13894): C2H2-type zinc finger |
305 |
ZC3H12A | interactor | 6 | 0.600 | 2.389 | RNase_Zc3h12a (PF11977, IPR021869): Zc3h12a-like Ribonuclease NYN domain zf-CCCH_2 (PF14608): RNA-binding, Nab2-type zinc finger |
306 |
ZCCHC14 | interactor | 3 | 0.667 | 1.000 | SAM_1 (PF00536, IPR021129, SM00454): SAM domain (Sterile alpha motif) SPX (PF03105, IPR004331): SPX domain zf-CCHC (PF00098, IPR001878): Zinc knuckle |
307 |
ZEB1 | interactor | 9 | 0.528 | 4.360 | CDC27 (PF09507, IPR019038): DNA polymerase subunit Cdc27 zf-Di19 (PF05605, IPR008598): Drought induced 19 protein (Di19), zinc-binding GET2 (PF08690, IPR028143): GET complex subunit GET2 Pox_Ag35 (PF03286, IPR004966): Pox virus Ag35 surface protein RNA_pol_Rpc4 (PF05132, IPR007811): RNA polymerase III RPC4 TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type Homeobox (PF00046, IPR001356, SM00389): Homeobox domain zf-C2H2_jaz (PF12171, IPR022755): Zinc-finger double-stranded RNA-binding zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain |
308 |
ZEB2 | oncoprotein | 8 | 0.500 | 4.023 | zf-Di19 (PF05605, IPR008598): Drought induced 19 protein (Di19), zinc-binding Rep_fac-A_C (PF08646, IPR013955): Replication factor-A C terminal domain Rubredoxin (PF00301, IPR024935): Rubredoxin zf-AN1 (PF01428, IPR000058, SM00154): AN1-like Zinc finger zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type Homeobox (PF00046, IPR001356, SM00389): Homeobox domain zf-C2H2_jaz (PF12171, IPR022755): Zinc-finger double-stranded RNA-binding SpoIIIAH (PF12685, IPR024232): SpoIIIAH-like protein zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_4 (PF13894): C2H2-type zinc finger zf-CCHC_5 (PF14787): GAG-polyprotein viral zinc-finger |
309 |
ZFYVE9 | interactor | 9 | 0.528 | 9.793 | FYVE (PF01363, IPR000306, SM00064): FYVE zinc finger SARA (PF11409, IPR024608): Smad anchor for receptor activation (SARA) DUF3480 (PF11979, IPR022557): Domain of unknown function (DUF3480) |
310 |
ZMIZ1 | oncoprotein | 10 | 0.489 | 5.987 | zf-MIZ (PF02891, IPR004181): MIZ/SP-RING zinc finger |
311 |
ZMYND11 | suppressor | 7 | 0.733 | 0.763 | DUF1002 (PF06207, IPR009343): Protein of unknown function (DUF1002) DUF1353 (PF07087, IPR010767): Protein of unknown function (DUF1353) PWWP (PF00855, IPR000313, SM00293): PWWP domain zf-MYND (PF01753, IPR002893): MYND finger zf-UBR (PF02207, IPR003126): Putative zinc finger in N-recognin (UBR box) Bromodomain (PF00439, IPR001487, SM00297): Bromodomain |
312 |
ZNF329 | interactor | 2 | 1.000 | 0 | zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain |
313 |
ZNF83 | interactor | 2 | 1.000 | 0 | zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain |