Find Fusion Network

Visualization interactions

Powered by Cytoscape Web for: parental proteins SMAD3 (from a repository: Fri Nov 11 23:18:27 2016)

Examples AFF1 MLL ACTN4 + MLLAFF1 + MLLALK + MSNALK + TFGALK + TPM3ALK + TPM4ASXL2 + KAT6AATF1 + FUSBCR + ABL1BCR + FGFR1CCND1 + TACSTD2CD74 + ROS1CDK6 + MLLCOL1A1 + PDGFBCREB3L2 + PPARGCREB3L2 + FUSCREBBP + KAT6ADAZAP1 + MEF2DELL + MLLEPS15 + MLLERG + EWSR1ERG + FUSERG + TMPRSS2ETV5 + TMPRSS2ETV6 + ABL1ETV6 + NTRK3ETV6 + PAX5EWSR1 + FLI1EWSR1 + WT1FOXO1 + PAX3FOXP1 + PAX5FRYL + MLLGAS7 + MLLGMPS + MLLGOLGA5 + RETHOOK3 + RETHOXC13 + NUP98HOXD13 + NUP98MECOM + RUNX1MKL1 + RBM15MLL + MLLT1MLL + MLLT4MLL + MLLT10MLL + PICALMMLLT10 + PICALMNCOA1 + PAX3NIN + PDGFRBNPM1 + RARANRG1 + ODZ4NTRK1 + TFGNUMA1 + RARANUP98 + PHF23PAX5 + ZNF521PBX1 + TCF3RET + TRIM27ROS1 + SLC34A2PML + RARAPRKAR1A + RARAPRKAR1A + RETRUNX1 + RUNX1T1RUNX1 + SH3D19	Cytoscape Web will replace the contents your graph	PPI Properties: Click on nodes or edges
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Statistics and Network structure information

Statistic of PPI Value(s) The number of interactors (fusion and proteins) 313 The number (and %) of the onco-proteins 105 (33.55 %) The number (and %) of the tumor suppressors 75 (23.96 %) Total number of binary PPIs (saturation %) 2586 (5.30 %) The number (and %) of affected PPIs 313 (12.10 %) The number of possible different fusions 72 PPI diameter 2 PPI radius 1 The average degree of PPI 15.668 Assortativity coefficient -0.2572 The network average Clustering coefficient 0.501 The number (and %) of a zero Clustering coefficients 10 (3.19 %) The number (and %) of a zero Betweenness Centrality 47 (15.02 %)

ACTIVE INTERACTORS

List of the fusions
PPI for parental proteins: SMAD3	All fusions : BF333017;
Proteins found in more fusions	AES (see 3 fusions); VDR (see 2 fusions); SMAD4 (see 2 fusions); U2AF2 (see 2 fusions); TCF12 (see 1 fusions); SETD2 (see 2 fusions); CUL1 (see 3 fusions); WWP1 (see 1 fusions); MDM4 (see 2 fusions); NUP153 (see 2 fusions); PAX6 (see 2 fusions); HDAC5 (see 1 fusions); SMARCC1 (see 2 fusions); EP300 (see 1 fusions); DDX5 (see 1 fusions); DACH1/SMAD4 (see 1 fusions); RPA1 (see 1 fusions); NEDD4 (see 1 fusions); GRIP1 (see 2 fusions); SNW1 (see 1 fusions); ZMYND11 (see 1 fusions); APP (see 4 fusions); FBLN1 (see 3 fusions); HDAC4 (see 1 fusions); DDX5/PIK3CA (see 1 fusions); NCOA1 (see 2 fusions); YY1 (see 2 fusions); NF2 (see 1 fusions); NEDD4L (see 3 fusions); RNF111 (see 1 fusions); BAG3 (see 4 fusions); RANBP9 (see 2 fusions); STUB1 (see 1 fusions); EPAS1 (see 1 fusions); TGM2 (see 4 fusions); PML (see 4 fusions); SUV39H1 (see 1 fusions); MAPK1 (see 1 fusions); CBL (see 1 fusions); NUP214 (see 1 fusions); GSK3B (see 1 fusions); HIPK2 (see 1 fusions); KDM5C (see 1 fusions); MYC (see 1 fusions); PIAS2 (see 2 fusions); SREBF2 (see 2 fusions); RUNX1 (see 1 fusions); KAT2B (see 1 fusions); ACTB (see 3 fusions); SMURF2 (see 1 fusions); SKI (see 1 fusions); DHX8 (see 1 fusions); ZBTB16 (see 3 fusions); STRAP (see 2 fusions); TP53 (see 3 fusions); FOXO1 (see 1 fusions); TRIM33 (see 1 fusions); NR3C1 (see 8 fusions); KPNB1 (see 2 fusions); PABPC1 (see 2 fusions); SQSTM1 (see 5 fusions); LCK (see 1 fusions); NCOA6 (see 1 fusions); SP1 (see 1 fusions); CREBBP (see 5 fusions); ERBIN (see 4 fusions); NEDD9 (see 1 fusions); FOS (see 4 fusions); MAP3K7 (see 7 fusions); SMAD3 (see 3 fusions); CDK9 (see 2 fusions);

List of active interactors

#	Name	Type	Number of PPI (degree)	Clustering Coefficient	Betweenness Centrality	Domains (Pfam, InterPro, SMART): description
1	SMAD3	parental protein	313	0.044	63570.500	MH1 (PF03165, IPR003619, SM00523): MH1 domain MH2 (PF03166, IPR001132, SM00524): MH2 domain
2	AATF	oncoprotein	10	0.422	12.533	DARPP-32 (PF05395, IPR008466): Protein phosphatase inhibitor 1/DARPP-32 RR_TM4-6 (PF06459, IPR009460): Ryanodine Receptor TM 4-6 TRAUB (PF08164, IPR012617): Apoptosis-antagonizing transcription factor, C-terminal Vif (PF00559, IPR000475): Retroviral Vif (Viral infectivity) protein AATF-Che1 (PF13339, IPR025160): Apoptosis antagonizing transcription factor
3	ACTB	oncoprotein	28	0.291	114.335	Actin (PF00022, IPR004000, SM00268): Actin
4	ACVR1B	oncoprotein	6	0.733	1.517	Activin_recp (PF01064, IPR000472): Activin types I and II receptor domain Pkinase (PF00069, IPR000719): Protein kinase domain TGF_beta_GS (PF08515, IPR003605, SM00467): Transforming growth factor beta type I GS-motif
5	AES	protein found in more fusions	12	0.218	25.353	TLE_N (PF03920, IPR005617): Groucho/TLE N-terminal Q-rich domain
6	AKT1	oncoprotein	39	0.266	222.446	PH (PF00169, IPR001849, SM00233): PH domain Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
7	ANAPC10	interactor	5	0.800	1.000	ANAPC10 (PF03256, IPR004939): Anaphase-promoting complex, subunit 10 (APC10)
8	ANK3	interactor	2	1.000	0	BRF1 (PF07741, IPR011665): Brf1-like TBP-binding domain Death (PF00531, IPR000488, SM00005): Death domain ZU5 (PF00791, IPR000906, SM00218): ZU5 domain DUF3008 (PF11450, IPR021553): Protein of unknwon function (DUF3008) DUF3439 (PF11921, IPR024592): Domain of unknown function (DUF3439) Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_4 (PF13637): Ankyrin repeats (many copies) Ank_5 (PF13857): Ankyrin repeats (many copies)
9	APMAP	interactor	2	1.000	0	Str_synth (PF03088, IPR018119): Strictosidine synthase
10	APOB	interactor	4	0.667	1.000	DUF1081 (PF06448, IPR009454): Domain of Unknown Function (DUF1081) DUF1943 (PF09172, IPR015255, SM01169): Domain of unknown function (DUF1943) Phage_holin_6_1 (PF09682, IPR010026): Bacteriophage holin of superfamily 6 (Holin_LLH) Vitellogenin_N (PF01347, IPR001747, SM00638): Lipoprotein amino terminal region DUF2807 (PF10988, IPR021255): Putative auto-transporter adhesin, head GIN domain ApoB100_C (PF12491, IPR022176): Apolipoprotein B100 C terminal
11	APP	protein found in more fusions	58	0.085	1068.798	APP_N (PF02177, IPR015849, SM00006): Amyloid A4 N-terminal heparin-binding Beta-APP (PF03494, IPR013803): Beta-amyloid peptide (beta-APP) BUD22 (PF09073, IPR015158): BUD22 IncA (PF04156, IPR007285): IncA protein Kunitz_BPTI (PF00014, IPR002223, SM00131): Kunitz/Bovine pancreatic trypsin inhibitor domain APP_amyloid (PF10515, IPR019543): beta-amyloid precursor protein C-terminus APP_Cu_bd (PF12924, IPR011178): Copper-binding of amyloid precursor, CuBD APP_E2 (PF12925, IPR024329): E2 domain of amyloid precursor protein
12	AR	oncoprotein	54	0.230	474.778	Androgen_recep (PF02166, IPR001103): Androgen receptor zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
13	ARID1A	suppressor	13	0.538	11.048	ARID (PF01388, IPR001606, SM00501): ARID/BRIGHT DNA binding domain Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein TAF4 (PF05236, IPR007900): Transcription initiation factor TFIID component TAF4 family YscJ_FliF_C (PF08345, IPR013556): Flagellar M-ring protein C-terminal TAT_signal (PF10518, IPR019546): TAT (twin-arginine translocation) pathway signal sequence BAF250_C (PF12031, IPR021906): SWI/SNF-like complex subunit BAF250/Osa Keratin_2_tail (PF16210, IPR032449): Keratin type II cytoskeletal 1 tail
14	ATF2	oncoprotein	26	0.310	106.091	bZIP_1 (PF00170, IPR004827): bZIP transcription factor zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
15	ATF3	suppressor	23	0.381	43.303	bZIP_1 (PF00170, IPR004827): bZIP transcription factor
16	ATXN2L	interactor	4	0.500	2.182	LsmAD (PF06741, IPR009604): LsmAD domain PAM2 (PF07145, IPR009818): Ataxin-2 C-terminal region SM-ATX (PF14438, IPR025852): Ataxin 2 SM domain
17	BACH1	interactor	8	0.619	3.308	BTB (PF00651, IPR013069, SM00225): BTB/POZ domain bZIP_Maf (PF03131, IPR004826): bZIP Maf transcription factor Cep57_CLD_2 (PF14197, IPR025925): Centrosome localisation domain of PPC89
18	BAG3	oncoprotein	12	0.291	32.138	BAG (PF02179, IPR003103, SM00264): BAG domain WW (PF00397, IPR001202, SM00456): WW domain
19	BLZF1	interactor	5	0.500	3.667	DASH_Hsk3 (PF08227, IPR013183): DASH complex subunit Hsk3 like DUF1178 (PF06676, IPR009562): Protein of unknown function (DUF1178) ZapB (PF06005, IPR009252): Cell division protein ZapB JIP_LZII (PF16471, IPR032486): JNK-interacting protein leucine zipper II
20	BMP7	interactor	3	1.000	0	TGFb_propeptide (PF00688, IPR001111): TGF-beta propeptide TGF_beta (PF00019, IPR001839, SM00204): Transforming growth factor beta like domain
21	BPTF	interactor	3	0.667	0.167	Arc_PepC_II (PF06847, IPR009655): Archaeal Peptidase A24 C-terminus Type II CobT (PF06213, IPR006538): Cobalamin biosynthesis protein CobT DDT (PF02791, IPR004022, SM00571): DDT domain DUF1764 (PF08576, IPR013885): Eukaryotic protein of unknown function (DUF1764) GRP (PF07172, IPR010800): Glycine rich protein family OAD_gamma (PF04277, IPR005899): Oxaloacetate decarboxylase, gamma chain PHD (PF00628, IPR019787, SM00249): PHD-finger SDA1 (PF05285, IPR007949): SDA1 Trypan_PARP (PF05887, IPR008882): Procyclic acidic repetitive protein (PARP) Bromodomain (PF00439, IPR001487, SM00297): Bromodomain WHIM1 (PF15612, IPR028942): WSTF, HB1, Itc1p, MBD9 motif 1 WSD (PF15613, IPR028941): Williams-Beuren syndrome DDT (WSD), D-TOX E motif CCSAP (PF15748, IPR029774): Centriole, cilia and spindle-associated PNISR (PF15996, IPR031937): Arginine/serine-rich protein PNISR
22	BRCA1	suppressor	52	0.245	451.782	BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger) BRCT_assoc (PF12820, IPR025994): Serine-rich domain associated with BRCT
23	BRCA2	suppressor	11	0.582	8.611	BRCA-2_helical (PF09169, IPR015252): BRCA2, helical BRCA-2_OB1 (PF09103, IPR015187): BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 BRCA-2_OB3 (PF09104, IPR015188): BRCA2, oligonucleotide/oligosaccharide-binding, domain 3 BRCA2 (PF00634, IPR002093): BRCA2 repeat Tower (PF09121, IPR015205): Tower
24	BTRC	oncoprotein	31	0.269	171.008	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Beta-TrCP_D (PF12125, IPR021977, SM01028): D domain of beta-TrCP ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain F-box-like (PF12937, IPR001810): F-box-like
25	BUB3	interactor	8	0.536	4.169	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
26	C10orf54	interactor	1	0	0	V-set (PF07686, IPR013106): Immunoglobulin V-set domain
27	C1orf116	interactor	3	0.667	0.069	SARG (PF15385): Specifically androgen-regulated gene protein
28	CAMK2G	interactor	5	0.700	0.683	CaMKII_AD (PF08332, IPR013543): Calcium/calmodulin dependent protein kinase II association domain Pkinase (PF00069, IPR000719): Protein kinase domain
29	CBL	suppressor	17	0.242	53.888	Cbl_N (PF02262, IPR003153): CBL proto-oncogene N-terminal domain 1 Cbl_N2 (PF02761, IPR014741): CBL proto-oncogene N-terminus, EF hand-like domain Cbl_N3 (PF02762, IPR014742): CBL proto-oncogene N-terminus, SH2-like domain UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain Prok-RING_4 (PF14447): Prokaryotic RING finger family 4 zf-RING_4 (PF14570): RING/Ubox like zinc-binding domain
30	CCDC33	interactor	8	0.500	9.141	C2 (PF00168, IPR000008, SM00239): C2 domain DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972) Pox_A_type_inc (PF04508, IPR007596): Viral A-type inclusion protein repeat SlyX (PF04102, IPR007236): SlyX
31	CDC16	interactor	9	0.556	7.666	Dynein_light (PF01221, IPR001372): Dynein light chain type 1 TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat ANAPC3 (PF12895): Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 (PF13424): Tetratricopeptide repeat TPR_17 (PF13431): Tetratricopeptide repeat TPR_16 (PF13432): Tetratricopeptide repeat SRP_TPR_like (PF17004, IPR031545): Putative TPR-like repeat
32	CDC25A	oncoprotein	7	0.476	6.147	M-inducer_phosp (PF06617, IPR000751): M-phase inducer phosphatase Rhodanese (PF00581, IPR001763, SM00450): Rhodanese-like domain
33	CDC27	oncoprotein	16	0.352	33.348	TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat ANAPC3 (PF12895): Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 (PF13414, IPR011990): TPR repeat TPR_12 (PF13424): Tetratricopeptide repeat
34	CDK11A	oncoprotein	3	0.667	0.286	DDHD (PF02862, IPR004177, SM01127): DDHD domain eIF_4EBP (PF05456, IPR008606): Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) Pkinase (PF00069, IPR000719): Protein kinase domain RIO1 (PF01163, IPR018934): RIO1 family DUF4355 (PF14265, IPR025580): Domain of unknown function (DUF4355) DHHW (PF14286, IPR025945): DHHW protein DUF4748 (PF15932, IPR031833): Domain of unknown function (DUF4748)
35	CDK2	suppressor	41	0.283	242.739	Kdo (PF06293, IPR010440): Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase (PF00069, IPR000719): Protein kinase domain
36	CDK4	oncoprotein	15	0.343	24.867	Pkinase (PF00069, IPR000719): Protein kinase domain
37	CDK8	interactor	20	0.503	27.487	Pkinase (PF00069, IPR000719): Protein kinase domain
38	CDK9	protein found in more fusions	15	0.484	12.953	Pkinase (PF00069, IPR000719): Protein kinase domain
39	CDKN1A	suppressor	27	0.348	87.506	CDI (PF02234, IPR003175): Cyclin-dependent kinase inhibitor
40	CEBPA	suppressor	28	0.345	76.356	Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator DUF2514 (PF10721, IPR019659): Protein of unknown function (DUF2514) bZIP_2 (PF07716, IPR004827, SM00338): Basic region leucine zipper
41	CEBPB	oncoprotein	31	0.446	61.656	RhlB (PF12300, IPR022077): ATP-dependent RNA helicase RhlB FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
42	CEBPD	suppressor	10	0.644	3.385	bZIP_2 (PF07716, IPR004827, SM00338): Basic region leucine zipper BST2 (PF16716, IPR024886): Bone marrow stromal antigen 2
43	CFDP1	interactor	2	1.000	0	BCNT (PF07572, IPR011421): Bucentaur or craniofacial development DUF789 (PF05623, IPR008507): Protein of unknown function (DUF789) YL1 (PF05764, IPR008895): YL1 nuclear protein DUF4048 (PF13257, IPR025122): Domain of unknown function (DUF4048)
44	CFH	oncoprotein	4	1.000	0	DUF1962 (PF09227, IPR015308): Domain of unknown function (DUF1962) Sushi (PF00084, IPR000436, SM00032): Sushi repeat (SCR repeat)
45	CFLAR	oncoprotein	7	0.533	4.686	DED (PF01335, IPR001875, SM00031): Death effector domain Peptidase_C14 (PF00656, IPR011600): Caspase domain
46	CHD8	oncoprotein	9	0.472	9.082	BUD22 (PF09073, IPR015158): BUD22 CHDCT2 (PF08074, IPR012957): CHDCT2 (NUC038) domain Chromo (PF00385, IPR023780, SM00298): Chromo (CHRromatin Organisation MOdifier) domain SelP_N (PF04592, IPR007671): Selenoprotein P, N terminal region SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain BRK (PF07533, IPR006576, SM00592): BRK domain SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain FAM176 (PF14851): FAM176 family Myb_DNA-bind_7 (PF15963): Myb DNA-binding like
47	CHRD	interactor	2	1.000	0	CHRD (PF07452, IPR010895, SM00754): CHRD domain VWC (PF00093, IPR001007, SM00214): von Willebrand factor type C domain
48	CHUK	suppressor	21	0.468	41.156	Pkinase (PF00069, IPR000719): Protein kinase domain IKKbetaNEMObind (PF12179, IPR022007): I-kappa-kinase-beta NEMO binding domain
49	CITED2	suppressor	5	0.900	0.118	CITED (PF04487, IPR007576): CITED
50	CORO1A	oncoprotein	4	0.500	2.500	DUF1899 (PF08953, IPR015048, SM01166): Domain of unknown function (DUF1899) Trimer_CC (PF08954, IPR015049, SM01167): Trimerisation motif WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain WD40_4 (PF16300): Type of WD40 repeat
51	CPSF7	interactor	8	0.429	8.478	CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term PRIMA1 (PF16101): Proline-rich membrane anchor 1
52	CPTP	interactor	1	0	0	GLTP (PF08718, IPR014830): Glycolipid transfer protein (GLTP)
53	CREBBP	suppressor	69	0.246	701.864	Creb_binding (PF09030, IPR014744): Creb binding DUF902 (PF06001, IPR010303): Domain of Unknown Function (DUF902) Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region KIX (PF02172, IPR003101): KIX domain MAS20 (PF02064, IPR002056): MAS20 protein import receptor TPX2 (PF06886, IPR027329): Targeting protein for Xklp2 (TPX2) zf-TAZ (PF02135, IPR000197, SM00551): TAZ zinc finger ANAPC_CDC26 (PF10471, IPR018860): Anaphase-promoting complex APC subunit CDC26 HAT_KAT11 (PF08214, IPR013178): Histone acetylation protein Bromodomain (PF00439, IPR001487, SM00297): Bromodomain ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type DUF3729 (PF12526, IPR022202): Protein of unknown function (DUF3729) DUF4834 (PF16118, IPR032272): Domain of unknown function (DUF4834)
54	CSH2	interactor	4	1.000	0	Hormone_1 (PF00103, IPR001400): Somatotropin hormone family
55	CSNK1D	interactor	11	0.418	10.234	Pkinase (PF00069, IPR000719): Protein kinase domain
56	CSNK1G2	interactor	2	1.000	0	Pkinase (PF00069, IPR000719): Protein kinase domain CK1gamma_C (PF12605, IPR022247): Casein kinase 1 gamma C terminal
57	CTCF	suppressor	5	0.400	4.317	cwf18 (PF08315, IPR013169): cwf18 pre-mRNA splicing factor zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_4 (PF13894): C2H2-type zinc finger zf-H2C2_5 (PF13909): C2H2-type zinc-finger domain PBP1_TM (PF14812, IPR032730): Transmembrane domain of transglycosylase PBP1 at N-terminal
58	CTNNB1	oncoprotein	57	0.210	587.389	Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat Atx10homo_assoc (PF09759, IPR019156): Spinocerebellar ataxia type 10 protein domain DUF3361 (PF11841, IPR024574): Domain of unknown function (DUF3361) HEAT_EZ (PF13513): HEAT-like repeat
59	CUL1	suppressor	37	0.224	260.432	Cullin (PF00888, IPR001373, SM00182): Cullin family Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
60	CXXC5	suppressor	6	0.400	3.556	Filament_head (PF04732, IPR006821): Intermediate filament head (DNA binding) region zf-CXXC (PF02008, IPR002857): CXXC zinc finger domain TAT_signal (PF10518, IPR019546): TAT (twin-arginine translocation) pathway signal sequence
61	CYP11A1	interactor	3	1.000	0	p450 (PF00067, IPR001128): Cytochrome P450
62	DAB2	suppressor	11	0.327	19.004	PID (PF00640, IPR006020, SM00462): Phosphotyrosine interaction domain (PTB/PID) zf-C2H2_assoc3 (PF16637): Putative zinc-finger between two C2H2 zinc-fingers on Patz
63	DACH1	suppressor	7	0.600	1.837	DUF508 (PF04370, IPR007465): Domain of unknown function (DUF508) Pap_E4 (PF02711, IPR003861): E4 protein Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein Secretin_N_2 (PF07655, IPR011514): Secretin N-terminal domain Ski_Sno (PF02437, IPR003380): SKI/SNO/DAC family Macoilin (PF09726, IPR019130): Transmembrane protein SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein
64	DCAF7	interactor	10	0.444	11.189	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
65	DDX3X	suppressor	12	0.530	7.607	DEAD (PF00270, IPR011545): DEAD/DEAH box helicase DUF755 (PF05501, IPR008474): Domain of unknown function (DUF755) Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
66	DDX3Y	interactor	3	1.000	0	DEAD (PF00270, IPR011545): DEAD/DEAH box helicase Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
67	DDX4	interactor	2	1.000	0	DEAD (PF00270, IPR011545): DEAD/DEAH box helicase Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
68	DDX5	oncoprotein	26	0.377	70.064	DEAD (PF00270, IPR011545): DEAD/DEAH box helicase P68HR (PF08061, IPR012587): P68HR (NUC004) repeat ResIII (PF04851, IPR006935): Type III restriction enzyme, res subunit Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
69	DEDD	interactor	4	0.667	0.667	DED (PF01335, IPR001875, SM00031): Death effector domain
70	DHX8	protein found in more fusions	7	0.467	6.071	DEAD (PF00270, IPR011545): DEAD/DEAH box helicase OB_NTP_bind (PF07717, IPR011709): Oligonucleotide/oligosaccharide-binding (OB)-fold DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777) HA2 (PF04408, IPR007502, SM00847): Helicase associated domain (HA2) S1 (PF00575, IPR003029, SM00316): S1 RNA binding domain Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
71	DNAJA2	interactor	9	0.556	5.917	DnaJ (PF00226, IPR001623, SM00271): DnaJ domain DnaJ_C (PF01556, IPR002939): DnaJ C terminal domain
72	DNAJB4	suppressor	4	0.667	1.500	DnaJ (PF00226, IPR001623, SM00271): DnaJ domain DnaJ_C (PF01556, IPR002939): DnaJ C terminal domain
73	DNMT3L	interactor	24	0.293	103.779	CEBP_ZZ (PF16366, IPR032296): Cytoplasmic polyadenylation element-binding protein ZZ domain
74	DOCK9	interactor	2	1.000	0	DHR-2 (PF06920, IPR010703): Dock homology region 2 PH (PF00169, IPR001849, SM00233): PH domain DUF3398 (PF11878, IPR021816): Domain of unknown function (DUF3398) DOCK-C2 (PF14429, IPR027007): C2 domain in Dock180 and Zizimin proteins
75	DVL1	interactor	12	0.564	7.509	DEP (PF00610, IPR000591, SM00049): Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Dishevelled (PF02377, IPR003351): Dishevelled specific domain PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) DIX (PF00778, IPR001158, SM00021): DIX domain Dsh_C (PF12316, IPR024580): Segment polarity protein dishevelled (Dsh) C terminal
76	DYRK1A	oncoprotein	8	0.524	3.836	DUF755 (PF05501, IPR008474): Domain of unknown function (DUF755) Filament_head (PF04732, IPR006821): Intermediate filament head (DNA binding) region Pkinase (PF00069, IPR000719): Protein kinase domain FAM199X (PF15814, IPR029672): Protein family FAM199X
77	E2F4	suppressor	12	0.470	9.033	E2F_TDP (PF02319, IPR003316): E2F/DP family winged-helix DNA-binding domain Pheromone (PF08015, IPR012597): Fungal mating-type pheromone SPX (PF03105, IPR004331): SPX domain DUF3584 (PF12128, IPR021979): Protein of unknown function (DUF3584) E2F_CC-MB (PF16421, IPR032198): E2F transcription factor CC-MB domain
78	EBI3	interactor	1	0	0	fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
79	EID2	interactor	4	1.000	0	Antimicrobial_5 (PF08026, IPR012524): Bee antimicrobial peptide
80	EIF4B	interactor	6	0.400	2.552	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3774 (PF12609, IPR022251): Wound-induced protein PROL5-SMR (PF15621, IPR026288): Proline-rich submaxillary gland androgen-regulated family
81	ELAC2	oncoprotein	5	0.600	2.213	Synthase_beta (PF11421, IPR020971): ATP synthase F1 beta subunit Lactamase_B_2 (PF12706, IPR001279): Beta-lactamase superfamily domain Lactamase_B_4 (PF13691, IPR027794): tRNase Z endonuclease
82	EP300	oncoprotein	88	0.175	1635.409	Creb_binding (PF09030, IPR014744): Creb binding DUF902 (PF06001, IPR010303): Domain of Unknown Function (DUF902) Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region KIX (PF02172, IPR003101): KIX domain RR_TM4-6 (PF06459, IPR009460): Ryanodine Receptor TM 4-6 TPX2 (PF06886, IPR027329): Targeting protein for Xklp2 (TPX2) zf-TAZ (PF02135, IPR000197, SM00551): TAZ zinc finger HAT_KAT11 (PF08214, IPR013178): Histone acetylation protein Bromodomain (PF00439, IPR001487, SM00297): Bromodomain ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type
83	EPAS1	suppressor	23	0.299	70.873	Corona_I (PF03187, IPR004876): Corona nucleocapsid I protein HIF-1a_CTAD (PF08778, IPR014887): HIF-1 alpha C terminal transactivation domain HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain PAS (PF00989, IPR013767, SM00091): PAS fold HIF-1 (PF11413, IPR021537): Hypoxia-inducible factor-1 PAS_11 (PF14598): PAS domain
84	EPB41L5	interactor	4	0.667	0.174	FA (PF08736, IPR014847): FERM adjacent (FA) FERM_C (PF09380, IPR018980): FERM C-terminal PH-like domain FERM_M (PF00373, IPR019748): FERM central domain FERM_N (PF09379, IPR018979): FERM N-terminal domain
85	ERBIN	oncoprotein	14	0.526	16.649	LRR_1 (PF00560, IPR001611): Leucine Rich Repeat Neur_chan_memb (PF02932, IPR006029): Neurotransmitter-gated ion-channel transmembrane region PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies) LRR_8 (PF13855, IPR001611): Leucine rich repeat
86	ESR1	suppressor	77	0.180	1226.665	Oest_recep (PF02159, IPR001292): Oestrogen receptor zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor ESR1_C (PF12743, IPR024736): Oestrogen-type nuclear receptor final C-terminal
87	ETS1	oncoprotein	20	0.474	39.387	Ets (PF00178, IPR000418, SM00413): Ets-domain SAM_PNT (PF02198, IPR003118, SM00251): Sterile alpha motif (SAM)/Pointed domain
88	FAM83G	interactor	2	1.000	0	DUF1669 (PF07894, IPR012461): Protein of unknown function (DUF1669) Trypan_PARP (PF05887, IPR008882): Procyclic acidic repetitive protein (PARP)
89	FBLN1	suppressor	6	0.600	2.178	ANATO (PF01821, IPR000020, SM00104): Anaphylotoxin-like domain EGF (PF00008, IPR000742, SM00181): EGF-like domain EGF_CA (PF07645, IPR001881, SM00179): Calcium-binding EGF domain cEGF (PF12662, IPR026823): Complement Clr-like EGF-like FXa_inhibition (PF14670): Coagulation Factor Xa inhibitory site
90	FHL1	suppressor	12	0.652	6.043	LIM (PF00412, IPR001781, SM00132): LIM domain zf-FCS (PF06467, IPR010507): MYM-type Zinc finger with FCS sequence motif
91	FHL2	oncoprotein	25	0.351	75.164	LIM (PF00412, IPR001781, SM00132): LIM domain zf-ribbon_3 (PF13248): zinc-ribbon domain
92	FHL3	interactor	13	0.303	33.806	LIM (PF00412, IPR001781, SM00132): LIM domain Med27 (PF11571, IPR021627): Mediator complex subunit 27
93	FLI1	oncoprotein	5	0.500	1.906	Ets (PF00178, IPR000418, SM00413): Ets-domain SAM_PNT (PF02198, IPR003118, SM00251): Sterile alpha motif (SAM)/Pointed domain
94	FLNA	suppressor	15	0.476	22.439	CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain Filamin (PF00630, IPR017868): Filamin/ABP280 repeat
95	FOS	oncoprotein	25	0.402	56.219	bZIP_1 (PF00170, IPR004827): bZIP transcription factor
96	FOXH1	interactor	6	0.600	3.286	Forkhead (PF00250, IPR001766, SM00339): Forkhead domain
97	FOXL2	suppressor	1	0	0	K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain Forkhead (PF00250, IPR001766, SM00339): Forkhead domain PRIMA1 (PF16101): Proline-rich membrane anchor 1
98	FOXM1	oncoprotein	8	0.429	8.252	EspF (PF04806, IPR006891): EspF protein repeat Forkhead (PF00250, IPR001766, SM00339): Forkhead domain
99	FOXO1	suppressor	19	0.484	20.422	K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain Forkhead (PF00250, IPR001766, SM00339): Forkhead domain FOXO_KIX_bdg (PF16675, IPR032068): KIX-binding domain of forkhead box O, CR2 FOXO-TAD (PF16676, IPR032067): Transactivation domain of FOXO protein family
100	FOXO3	suppressor	19	0.480	26.835	Lin-8 (PF03353, IPR005020): Ras-mediated vulval-induction antagonist Forkhead (PF00250, IPR001766, SM00339): Forkhead domain FOXO_KIX_bdg (PF16675, IPR032068): KIX-binding domain of forkhead box O, CR2 FOXO-TAD (PF16676, IPR032067): Transactivation domain of FOXO protein family
101	FOXO4	suppressor	10	0.533	5.073	Forkhead (PF00250, IPR001766, SM00339): Forkhead domain FOXO_KIX_bdg (PF16675, IPR032068): KIX-binding domain of forkhead box O, CR2 FOXO-TAD (PF16676, IPR032067): Transactivation domain of FOXO protein family
102	GGA1	oncoprotein	4	0.667	0.500	Alpha_adaptinC2 (PF02883, IPR008152, SM00809): Adaptin C-terminal domain GAT (PF03127, IPR004152): GAT domain Hormone_3 (PF00159, IPR001955): Pancreatic hormone peptide VHS (PF00790, IPR002014, SM00288): VHS domain AP3B1_C (PF14796, IPR029390): Clathrin-adaptor complex-3 beta-1 subunit C-terminal
103	GIT2	interactor	5	0.500	3.000	ArfGap (PF01412, IPR001164, SM00105): Putative GTPase activating protein for Arf Sen15 (PF09631, IPR018593): Sen15 protein GIT_SHD (PF08518, IPR013724, SM00555): Spa2 homology domain (SHD) of GIT GIT1_C (PF12205, IPR022018): G protein-coupled receptor kinase-interacting protein 1 C term Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) DUF4482 (PF14818, IPR027882): Domain of unknown function (DUF4482) GIT_CC (PF16559, IPR032352): GIT coiled-coil Rho guanine nucleotide exchange factor
104	GMEB1	interactor	3	1.000	0	Adeno_PV (PF03910, IPR005608): Adenovirus minor core protein PV SAND (PF01342, IPR000770, SM00258): SAND domain
105	GRIP1	protein found in more fusions	12	0.764	1.838	PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
106	GSK3B	suppressor	30	0.273	135.955	Pkinase (PF00069, IPR000719): Protein kinase domain
107	HDAC1	suppressor	72	0.203	1027.597	FSAP_sig_propep (PF03032, IPR004275): Frog skin active peptide family signal and propeptide Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
108	HDAC4	oncoprotein	27	0.268	89.825	Borrelia_P83 (PF05262, IPR007926): Borrelia P83/100 protein Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit HDAC4_Gln (PF12203, IPR024643): Glutamine rich N terminal domain of histone deacetylase 4
109	HDAC5	protein found in more fusions	33	0.228	199.698	Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain NOA36 (PF06524, IPR010531): NOA36 protein Activator_LAG-3 (PF11498, IPR021587): Transcriptional activator LAG-3 HDAC4_Gln (PF12203, IPR024643): Glutamine rich N terminal domain of histone deacetylase 4
110	HEY1	oncoprotein	4	0.667	0.508	Hairy_orange (PF07527, IPR003650): Hairy Orange HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain HTH_Crp_2 (PF13545, IPR012318): Crp-like helix-turn-helix domain
111	HEYL	interactor	5	0.500	1.291	Hairy_orange (PF07527, IPR003650): Hairy Orange HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
112	HGS	interactor	18	0.242	73.778	FYVE (PF01363, IPR000306, SM00064): FYVE zinc finger UIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif VHS (PF00790, IPR002014, SM00288): VHS domain EF-1_beta_acid (PF10587, IPR018940): Eukaryotic elongation factor 1 beta central acidic region Hrs_helical (PF12210, IPR024641): Hepatocyte growth factor-regulated tyrosine kinase substrate PIEZO (PF15917, IPR031805): Piezo
113	HIF1A	suppressor	32	0.393	110.680	Dicty_REP (PF05086, IPR007778): Dictyostelium (Slime Mold) REP protein HIF-1a_CTAD (PF08778, IPR014887): HIF-1 alpha C terminal transactivation domain HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain PAS (PF00989, IPR013767, SM00091): PAS fold PAS_3 (PF08447, IPR013655): PAS fold HIF-1 (PF11413, IPR021537): Hypoxia-inducible factor-1
114	HIPK2	suppressor	19	0.386	43.501	Kdo (PF06293, IPR010440): Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase (PF00069, IPR000719): Protein kinase domain
115	HIVEP1	suppressor	5	0.400	2.206	PHD (PF00628, IPR019787, SM00249): PHD-finger PyrI_C (PF02748, IPR020542): Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-C2H2_2 (PF12756, IPR015880): C2H2 type zinc-finger (2 copies) zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-H2C2_5 (PF13909): C2H2-type zinc-finger domain zf-C2H2_7 (PF15269): Zinc-finger
116	HNF4A	suppressor	18	0.441	27.337	zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
117	HNRNPK	oncoprotein	29	0.317	116.208	ROKNT (PF08067, IPR012987): ROKNT (NUC014) domain KH_1 (PF00013, IPR004088, SM00322): KH domain
118	HOXC11	oncoprotein	4	0.500	0.668	DUF3528 (PF12045, IPR021918): Protein of unknown function (DUF3528)
119	HP	interactor	3	0.667	0.667	Sushi (PF00084, IPR000436, SM00032): Sushi repeat (SCR repeat) Trypsin (PF00089, IPR001254, SM00020): Trypsin
120	HSPA4	interactor	32	0.250	177.459	Herpes_ICP4_N (PF03584, IPR005206): Herpesvirus ICP4-like protein N-terminal region HSP70 (PF00012, IPR013126): Hsp70 protein TP53IP5 (PF15331, IPR029290): Cellular tumour antigen p53-inducible 5
121	IRF7	interactor	10	0.556	10.272	IRF (PF00605, IPR001346, SM00348): Interferon regulatory factor transcription factor IRF-3 (PF10401, IPR019471): Interferon-regulatory factor 3
122	IRS1	interactor	9	0.528	5.632	CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal IRS (PF02174, IPR002404, SM00310): PTB domain (IRS-1 type) PH (PF00169, IPR001849, SM00233): PH domain
123	ISL1	interactor	5	0.667	0.248	LIM (PF00412, IPR001781, SM00132): LIM domain Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
124	ITCH	interactor	27	0.249	134.101	C2 (PF00168, IPR000008, SM00239): C2 domain WW (PF00397, IPR001202, SM00456): WW domain HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
125	ITGB4	oncoprotein	6	0.467	3.952	Calx-beta (PF03160, IPR003644, SM00237): Calx-beta domain EGF_2 (PF07974, IPR013111): EGF-like domain fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain Integrin_B_tail (PF07965, IPR012896): Integrin beta tail domain SEA (PF01390, IPR000082, SM00200): SEA domain STOP (PF05217, IPR024963): STOP protein Integrin_beta (PF00362, IPR002369, SM00187): Integrin, beta chain PSI_integrin (PF17205): Integrin plexin domain
126	JUN	oncoprotein	49	0.317	280.802	bZIP_1 (PF00170, IPR004827): bZIP transcription factor Jun (PF03957, IPR005643): Jun-like transcription factor
127	JUNB	oncoprotein	12	0.485	7.135	bZIP_1 (PF00170, IPR004827): bZIP transcription factor Jun (PF03957, IPR005643): Jun-like transcription factor
128	JUND	oncoprotein	12	0.424	12.682	bZIP_1 (PF00170, IPR004827): bZIP transcription factor Jun (PF03957, IPR005643): Jun-like transcription factor
129	KANSL1	interactor	3	0.667	1.000	PEHE (PF15275, IPR029332): PEHE domain
130	KAT2A	interactor	17	0.358	25.545	Acetyltransf_1 (PF00583, IPR000182): Acetyltransferase (GNAT) family PCAF_N (PF06466, IPR009464): PCAF (P300/CBP-associated factor) N-terminal domain Bromodomain (PF00439, IPR001487, SM00297): Bromodomain NICE-1 (PF15845, IPR031698): Cysteine-rich C-terminal 1 family
131	KAT2B	protein found in more fusions	34	0.333	133.736	Acetyltransf_1 (PF00583, IPR000182): Acetyltransferase (GNAT) family PCAF_N (PF06466, IPR009464): PCAF (P300/CBP-associated factor) N-terminal domain Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
132	KDM2A	interactor	4	0.667	0.917	JmjC (PF02373, IPR003347, SM00558): JmjC domain, hydroxylase Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein zf-CXXC (PF02008, IPR002857): CXXC zinc finger domain F-box (PF00646, IPR001810, SM00256): F-box domain DZR (PF12773, IPR025874): Double zinc ribbon LRR_6 (PF13516, IPR001611): Leucine Rich repeat LRR_8 (PF13855, IPR001611): Leucine rich repeat PHD_4 (PF16866, IPR019787): PHD-finger
133	KDM5C	oncoprotein	4	0.667	0.182	ARID (PF01388, IPR001606, SM00501): ARID/BRIGHT DNA binding domain JmjC (PF02373, IPR003347, SM00558): JmjC domain, hydroxylase JmjN (PF02375, IPR003349, SM00545): jmjN domain PHD (PF00628, IPR019787, SM00249): PHD-finger PLU-1 (PF08429, IPR013637): PLU-1-like protein FYVE_2 (PF02318, IPR010911): FYVE-type zinc finger zf-C5HC2 (PF02928, IPR004198): C5HC2 zinc finger
134	KDM6B	interactor	4	1.000	0	Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator JmjC (PF02373, IPR003347, SM00558): JmjC domain, hydroxylase Mucin (PF01456, IPR000458): Mucin-like glycoprotein
135	KLF5	suppressor	17	0.551	15.212	zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
136	KMT2B	oncoprotein	4	0.500	0.700	FLO_LFY (PF01698, IPR002910): Floricaula / Leafy protein FYRC (PF05965, IPR003889, SM00542): F/Y rich C-terminus FYRN (PF05964, IPR003888, SM00541): F/Y-rich N-terminus GRP (PF07172, IPR010800): Glycine rich protein family PHD (PF00628, IPR019787, SM00249): PHD-finger SET (PF00856, IPR001214, SM00317): SET domain zf-CXXC (PF02008, IPR002857): CXXC zinc finger domain Bromodomain (PF00439, IPR001487, SM00297): Bromodomain Fer4_2 (PF12797, IPR001450): 4Fe-4S binding domain zf-HC5HC2H (PF13771): PHD-like zinc-binding domain FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 AIM3 (PF17096, IPR031370): Altered inheritance of mitochondria protein 3
137	KPNB1	protein found in more fusions	22	0.267	80.847	Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat HEAT (PF02985, IPR000357): HEAT repeat IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain V-ATPase_H_C (PF11698, IPR011987): V-ATPase subunit H CLASP_N (PF12348, IPR024395): CLASP N terminal Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1 HEAT_EZ (PF13513): HEAT-like repeat
138	LACRT	interactor	3	1.000	0	NA
139	LBP	interactor	2	1.000	0	LBP_BPI_CETP (PF01273, IPR017942, SM00328): LBP / BPI / CETP family, N-terminal domain LBP_BPI_CETP_C (PF02886, IPR001124, SM00329): LBP / BPI / CETP family, C-terminal domain
140	LCK	oncoprotein	12	0.382	17.668	Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
141	LDLRAD4	interactor	12	0.364	21.679	Ldl_recept_a (PF00057, IPR002172, SM00192): Low-density lipoprotein receptor domain class A DUF2615 (PF11027, IPR020309): Protein of unknown function (DUF2615)
142	LEF1	oncoprotein	12	0.621	12.264	CTNNB1_binding (PF08347, IPR013558): N-terminal CTNNB1 binding HMG_box (PF00505, IPR009071, SM00398): HMG (high mobility group) box
143	LEMD3	interactor	4	0.833	0.222	LEM (PF03020, IPR003887, SM00540): LEM domain MSC (PF09402, IPR018996): Man1-Src1p-C-terminal domain RBM39linker (PF15519, IPR029123): linker between RRM2 and RRM3 domains in RBM39 protein
144	LRCH1	interactor	2	1.000	0	CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain LRR_1 (PF00560, IPR001611): Leucine Rich Repeat LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies) LRR_8 (PF13855, IPR001611): Leucine rich repeat JAKMIP_CC3 (PF16034, IPR031994): JAKMIP CC3 domain
145	MAFK	oncoprotein	8	0.786	1.908	bZIP_Maf (PF03131, IPR004826): bZIP Maf transcription factor
146	MAP3K7	oncoprotein	17	0.217	46.900	Mnd1 (PF03962, IPR005647): Mnd1 family Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
147	MAPK1	oncoprotein	37	0.316	186.182	Pkinase (PF00069, IPR000719): Protein kinase domain
148	MAPK8	oncoprotein	25	0.319	84.106	DUF530 (PF04409, IPR007503): Protein of unknown function (DUF530) Pkinase (PF00069, IPR000719): Protein kinase domain
149	MAX	suppressor	14	0.385	20.312	ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16) HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain SlyX (PF04102, IPR007236): SlyX
150	MCM3AP	interactor	5	0.500	3.250	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SAC3_GANP (PF03399, IPR005062): SAC3/GANP family G_path_suppress (PF15991, IPR026094): G-protein pathway suppressor CID_GANP (PF16766, IPR031910): Binding region of GANP to ENY2 NupH_GANP (PF16768, IPR031908): Nucleoporin homology of Germinal-centre associated nuclear protein MCM3AP_GANP (PF16769, IPR031907): MCM3AP domain of GANP
151	MDM4	oncoprotein	9	0.607	3.115	zf-FLZ (PF04570, IPR007650): zinc-finger of the FCS-type, C2-C2 SWIB (PF02201, IPR003121, SM00151): SWIB/MDM2 domain zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
152	MECOM	oncoprotein	10	0.600	4.347	SET (PF00856, IPR001214, SM00317): SET domain zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_6 (PF13912, IPR007087): C2H2-type zinc finger
153	MED15	interactor	11	0.491	11.344	Med15 (PF09606, IPR019087): ARC105 or Med15 subunit of Mediator complex non-fungal
154	MED24	interactor	15	0.381	21.521	Med24_N (PF11277, IPR021429): Mediator complex subunit 24 N-terminal
155	MED6	interactor	10	0.600	5.820	Med6 (PF04934, IPR007018): MED6 mediator sub complex component Peptidase_M15 (PF01427, IPR000755): D-ala-D-ala dipeptidase
156	MEN1	suppressor	14	0.505	11.957	Menin (PF05053, IPR007747): Menin
157	MEOX2	interactor	5	0.500	5.000	Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
158	MKL1	oncoprotein	6	0.600	2.092	RPEL (PF02755, IPR004018, SM00707): RPEL repeat SAP (PF02037, IPR003034, SM00513): SAP domain Troponin-I_N (PF11636, IPR021666): Troponin I residues 1-32
159	MTF2	interactor	3	0.667	0.333	PHD (PF00628, IPR019787, SM00249): PHD-finger FYVE_2 (PF02318, IPR010911): FYVE-type zinc finger Mtf2_C (PF14061, IPR025894): Polycomb-like MTF2 factor 2 DUF4537 (PF15057, IPR032770): Domain of unknown function (DUF4537)
160	MYC	oncoprotein	66	0.208	815.933	HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain Myc-LZ (PF02344, IPR003327): Myc leucine zipper domain Myc_N (PF01056, IPR012682): Myc amino-terminal region
161	MYD88	oncoprotein	8	0.286	9.867	Death (PF00531, IPR000488, SM00005): Death domain TIR (PF01582, IPR000157, SM00255): TIR domain
162	MYOCD	interactor	7	0.619	3.154	BES1_N (PF05687, IPR008540): BES1/BZR1 plant transcription factor, N-terminal IncA (PF04156, IPR007285): IncA protein RPEL (PF02755, IPR004018, SM00707): RPEL repeat SAP (PF02037, IPR003034, SM00513): SAP domain Totivirus_coat (PF05518, IPR008871): Totivirus coat protein
163	NCOA1	oncoprotein	26	0.493	41.575	DUF1518 (PF07469, IPR010011, SM01151): Domain of unknown function (DUF1518) HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain Nuc_rec_co-act (PF08815, IPR014920): Nuclear receptor coactivator PAS (PF00989, IPR013767, SM00091): PAS fold PAS_3 (PF08447, IPR013655): PAS fold SRC-1 (PF08832, IPR014935): Steroid receptor coactivator PAS_11 (PF14598): PAS domain DUF4927 (PF16279, IPR032565): Domain of unknown function (DUF4927) NCOA_u2 (PF16665): Unstructured region on nuclear receptor coactivator protein
164	NCOA3	oncoprotein	26	0.422	64.010	DUF1518 (PF07469, IPR010011, SM01151): Domain of unknown function (DUF1518) HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain Nuc_rec_co-act (PF08815, IPR014920): Nuclear receptor coactivator PAS (PF00989, IPR013767, SM00091): PAS fold PAS_3 (PF08447, IPR013655): PAS fold Pex14_N (PF04695, IPR006785): Peroxisomal membrane anchor protein (Pex14p) conserved region SRC-1 (PF08832, IPR014935): Steroid receptor coactivator PAS_11 (PF14598): PAS domain DUF4927 (PF16279, IPR032565): Domain of unknown function (DUF4927) NCOA_u2 (PF16665): Unstructured region on nuclear receptor coactivator protein AIM3 (PF17096, IPR031370): Altered inheritance of mitochondria protein 3
165	NCOA6	oncoprotein	22	0.481	42.100	DUF719 (PF05334, IPR007998): Protein of unknown function (DUF719) Fes1 (PF08609, IPR013918): Nucleotide exchange factor Fes1 Presenilin (PF01080, IPR001108): Presenilin DUF3729 (PF12526, IPR022202): Protein of unknown function (DUF3729) Nucleic_acid_bd (PF13820, IPR032715): Putative nucleic acid-binding region NST1 (PF13945, IPR025279): Salt tolerance down-regulator
166	NEDD4	suppressor	25	0.261	89.087	Rota_NS26 (PF01525, IPR002512): Rotavirus NS26 WW (PF00397, IPR001202, SM00456): WW domain HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
167	NEDD4L	suppressor	12	0.364	20.457	WW (PF00397, IPR001202, SM00456): WW domain HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
168	NEDD9	protein found in more fusions	9	0.536	5.386	Serine_rich (PF08824, IPR014928): Serine rich protein interaction domain DUF3513 (PF12026, IPR021901): Domain of unknown function (DUF3513) SH3_9 (PF14604, IPR001452): Variant SH3 domain
169	NF2	suppressor	15	0.231	35.162	ERM (PF00769, IPR011259): Ezrin/radixin/moesin family FERM_C (PF09380, IPR018980): FERM C-terminal PH-like domain FERM_M (PF00373, IPR019748): FERM central domain FERM_N (PF09379, IPR018979): FERM N-terminal domain
170	NFIA	interactor	3	1.000	0	CTF_NFI (PF00859, IPR000647): CTF/NF-I family transcription modulation region NfI_DNAbd_pre-N (PF10524, IPR019548): Nuclear factor I protein pre-N-terminus MH1 (PF03165, IPR003619, SM00523): MH1 domain
171	NFIC	oncoprotein	3	0.667	1.000	CTF_NFI (PF00859, IPR000647): CTF/NF-I family transcription modulation region NfI_DNAbd_pre-N (PF10524, IPR019548): Nuclear factor I protein pre-N-terminus MH1 (PF03165, IPR003619, SM00523): MH1 domain
172	NFYC	interactor	8	0.714	1.961	CBFD_NFYB_HMF (PF00808, IPR003958): Histone-like transcription factor (CBF/NF-Y) and archaeal histone E1-E2_ATPase (PF00122, IPR008250): E1-E2 ATPase Fucose_iso_C (PF02952, IPR015888): L-fucose isomerase, C-terminal domain
173	NOTCH1	suppressor	39	0.161	306.174	Ank (PF00023, IPR002110, SM00248): Ankyrin repeat EGF (PF00008, IPR000742, SM00181): EGF-like domain EGF_2 (PF07974, IPR013111): EGF-like domain EGF_alliinase (PF04863, IPR006947): Alliinase EGF-like domain EGF_CA (PF07645, IPR001881, SM00179): Calcium-binding EGF domain NOD (PF06816, IPR010660): NOTCH protein NODP (PF07684, IPR011656): NOTCH protein TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit Notch (PF00066, IPR000800, SM00004): LNR domain DUF3454 (PF11936, IPR024600): Domain of unknown function (DUF3454) hEGF (PF12661, IPR013032): Human growth factor-like EGF cEGF (PF12662, IPR026823): Complement Clr-like EGF-like Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
174	NOTCH4	oncoprotein	4	0.833	0.065	EGF (PF00008, IPR000742, SM00181): EGF-like domain EGF_2 (PF07974, IPR013111): EGF-like domain EGF_alliinase (PF04863, IPR006947): Alliinase EGF-like domain EGF_CA (PF07645, IPR001881, SM00179): Calcium-binding EGF domain Lem_TRP (PF08262, IPR013206): Leucophaea maderae tachykinin-related peptide NOD (PF06816, IPR010660): NOTCH protein NODP (PF07684, IPR011656): NOTCH protein Notch (PF00066, IPR000800, SM00004): LNR domain hEGF (PF12661, IPR013032): Human growth factor-like EGF cEGF (PF12662, IPR026823): Complement Clr-like EGF-like Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_5 (PF13857): Ankyrin repeats (many copies) FXa_inhibition (PF14670): Coagulation Factor Xa inhibitory site
175	NR3C1	protein found in more fusions	29	0.339	103.801	GCR (PF02155, IPR001409): Glucocorticoid receptor zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
176	NR4A1	suppressor	17	0.478	21.231	zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
177	NUP153	protein found in more fusions	12	0.418	14.297	Nup153 (PF08604, IPR013913): Nucleoporin Nup153-like Nup_retrotrp_bd (PF10599, IPR018892): Retro-transposon transporting motif zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others Nucleoporin_FG (PF13634, IPR025574): Nucleoporin FG repeat region
178	NUP214	oncoprotein	9	0.536	4.231	dCache_2 (PF08269, IPR004010, SM01049): Cache domain HisKA (PF00512, IPR003661, SM00388): His Kinase A (phospho-acceptor) domain MIP-T3 (PF10243): Microtubule-binding protein MIP-T3 ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_FG (PF13634, IPR025574): Nucleoporin FG repeat region Mustang (PF15682, IPR031394): Musculoskeletal, temporally activated-embryonic nuclear protein 1 NUP214 (PF16755): Nucleoporin or Nuclear pore complex subunit NUP214=Nup159
179	OPA1	interactor	4	0.833	0.069	DUF1593 (PF07632, IPR011483): Protein of unknown function (DUF1593) Ephrin_rec_like (PF07699, IPR011641): Putative ephrin-receptor like IncA (PF04156, IPR007285): IncA protein Ras (PF00071, IPR001806, SM00173): Ras family Dynamin_N (PF00350, IPR001401, SM00053): Dynamin family DUF4061 (PF13270, IPR025271): Domain of unknown function (DUF4061)
180	OTUB1	interactor	20	0.289	76.184	Peptidase_C65 (PF10275, IPR019400): Peptidase C65 Otubain
181	PABPC1	oncoprotein	23	0.312	91.310	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP (PF00658, IPR002004, SM00517): Poly-adenylate binding protein, unique domain YflT (PF11181, IPR025889): Heat induced stress protein YflT
182	PAPPA	interactor	5	0.600	1.889	Peptidase_M43 (PF05572, IPR008754): Pregnancy-associated plasma protein-A Sushi (PF00084, IPR000436, SM00032): Sushi repeat (SCR repeat) Notch (PF00066, IPR000800, SM00004): LNR domain Laminin_G_3 (PF13385): Concanavalin A-like lectin/glucanases superfamily DUF4215 (PF13948, IPR011936): Domain of unknown function (DUF4215)
183	PARD3	interactor	8	0.679	3.314	PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) DUF3534 (PF12053, IPR021922): Domain of unknown function (DUF3534) PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
184	PARP4	interactor	1	0	0	BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain PARP (PF00644, IPR012317): Poly(ADP-ribose) polymerase catalytic domain PARP_reg (PF02877, IPR004102): Poly(ADP-ribose) polymerase, regulatory domain VIT (PF08487, IPR013694, SM00609): Vault protein inter-alpha-trypsin domain VWA (PF00092, IPR002035, SM00327): von Willebrand factor type A domain
185	PAX6	suppressor	12	0.455	17.530	PAX (PF00292, IPR001523, SM00351): 'Paired box' domain Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
186	PCDH1	interactor	1	0	0	Cadherin_2 (PF08266, IPR013164): Cadherin-like Protocadherin (PF08374, IPR013585): Protocadherin Cadherin (PF00028, IPR002126, SM00112): Cadherin domain RGCC (PF15151, IPR029252): Response gene to complement 32 protein family Cadherin_3 (PF16184): Cadherin-like
187	PCK2	interactor	3	0.667	0.111	PEPCK (PF00821, IPR008209): Phosphoenolpyruvate carboxykinase
188	PHC2	interactor	3	1.000	0	SAM_1 (PF00536, IPR021129, SM00454): SAM domain (Sterile alpha motif) TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit zf-CGNR (PF11706, IPR021005): CGNR zinc finger DUF4692 (PF15763, IPR031517): Domain of unknown function (DUF4692) PHC2_SAM_assoc (PF16616): Unstructured region on Polyhomeotic-like protein 1 and 2
189	PIAS2	protein found in more fusions	17	0.358	34.130	SAP (PF02037, IPR003034, SM00513): SAP domain zf-MIZ (PF02891, IPR004181): MIZ/SP-RING zinc finger PINIT (PF14324, IPR023321): PINIT domain
190	PIAS3	oncoprotein	12	0.500	11.793	SAP (PF02037, IPR003034, SM00513): SAP domain zf-MIZ (PF02891, IPR004181): MIZ/SP-RING zinc finger PINIT (PF14324, IPR023321): PINIT domain
191	PIAS4	interactor	20	0.384	54.291	CENP-B_dimeris (PF09026, IPR015115): Centromere protein B dimerisation domain SAP (PF02037, IPR003034, SM00513): SAP domain zf-MIZ (PF02891, IPR004181): MIZ/SP-RING zinc finger PINIT (PF14324, IPR023321): PINIT domain
192	PIK3CA	oncoprotein	12	0.470	14.968	PI3K_C2 (PF00792, IPR002420, SM00142): Phosphoinositide 3-kinase C2 PI3K_p85B (PF02192, IPR003113, SM00143): PI3-kinase family, p85-binding domain PI3K_rbd (PF00794, IPR000341, SM00144): PI3-kinase family, ras-binding domain PI3Ka (PF00613, IPR001263, SM00145): Phosphoinositide 3-kinase family, accessory domain (PIK domain) DUF2321 (PF10083, IPR016891): Uncharacterized protein conserved in bacteria (DUF2321) PI3_PI4_kinase (PF00454, IPR000403, SM00146): Phosphatidylinositol 3- and 4-kinase
193	PIN1	suppressor	35	0.240	273.976	Rotamase (PF00639, IPR000297): PPIC-type PPIASE domain WW (PF00397, IPR001202, SM00456): WW domain
194	PITX1	oncoprotein	3	0.667	0.667	Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region OAR (PF03826, IPR003654): OAR domain Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
195	PITX2	interactor	5	1.000	0	OAR (PF03826, IPR003654): OAR domain XRCC4 (PF06632, IPR010585): DNA double-strand break repair and V(D)J recombination protein XRCC4 Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
196	PJA1	interactor	7	0.333	5.519	zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain
197	PLAG1	oncoprotein	3	1.000	0	zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_4 (PF13894): C2H2-type zinc finger zf-C2H2_6 (PF13912, IPR007087): C2H2-type zinc finger
198	PLAGL1	suppressor	8	0.750	1.096	zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_4 (PF13894): C2H2-type zinc finger zf-C2H2_6 (PF13912, IPR007087): C2H2-type zinc finger
199	PLG	interactor	6	0.600	3.165	Kringle (PF00051, IPR000001): Kringle domain PAN_1 (PF00024, IPR003014): PAN domain Trypsin (PF00089, IPR001254, SM00020): Trypsin
200	PML	suppressor	44	0.246	300.194	zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger DUF3583 (PF12126, IPR021978): Protein of unknown function (DUF3583) zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
201	PPARG	suppressor	33	0.351	118.755	zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor PPARgamma_N (PF12577, IPR022590): PPAR gamma N-terminal region
202	PPP1R12C	interactor	2	0	0	MSA-2c (PF12238, IPR021060): Merozoite surface antigen 2c Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_5 (PF13857): Ankyrin repeats (many copies) DUF4695 (PF15766, IPR031521): Domain of unknown function (DUF4695) PRKG1_interact (PF15898, IPR031775): cGMP-dependent protein kinase interacting domain
203	PPP2R1A	oncoprotein	18	0.320	46.339	TAF6_C (PF07571, IPR011442): TAF6 C-terminal HEAT repeat domain HEAT (PF02985, IPR000357): HEAT repeat HEAT_PBS (PF03130, IPR004155, SM00567): PBS lyase HEAT-like repeat HEAT_2 (PF13646): HEAT repeats
204	PRDM16	oncoprotein	3	1.000	0	SET (PF00856, IPR001214, SM00317): SET domain zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_6 (PF13912, IPR007087): C2H2-type zinc finger
205	PRDM4	suppressor	4	0.667	0.400	zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type Ecl1 (PF12855, IPR024368): Life-span regulatory factor zf-met (PF12874): Zinc-finger of C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
206	PROX1	suppressor	6	0.400	7.043	GET2 (PF08690, IPR028143): GET complex subunit GET2 NifQ (PF04891, IPR006975): NifQ HPD (PF05044, IPR023082): Homeo-prospero domain PP_kinase_N (PF13089, IPR025198): Polyphosphate kinase N-terminal domain Metal_resist (PF13801, IPR025961): Heavy-metal resistance
207	PRTN3	interactor	1	0	0	Trypsin (PF00089, IPR001254, SM00020): Trypsin
208	PSMD11	interactor	14	0.418	19.174	DUF247 (PF03140, IPR004158): Plant protein of unknown function PCI (PF01399, IPR000717, SM00088): PCI domain AAA_16 (PF13191): AAA ATPase domain TPR_12 (PF13424): Tetratricopeptide repeat
209	PSPC1	interactor	6	0.533	3.876	FUSC (PF04632, IPR006726): Fusaric acid resistance protein family NOPS (PF08075, IPR012975): NOPS (NUC059) domain RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Zot (PF05707, IPR008900): Zonular occludens toxin (Zot)
210	PTPN6	suppressor	4	0.667	1.667	SH2 (PF00017, IPR000980, SM00252): SH2 domain Y_phosphatase (PF00102, IPR000242, SM00194): Protein-tyrosine phosphatase PolyA_pol_arg_C (PF12626, IPR025866): Polymerase A arginine-rich C-terminus
211	RAB11FIP5	interactor	3	1.000	0	C2 (PF00168, IPR000008, SM00239): C2 domain Herpes_PAP (PF03325, IPR004997): Herpesvirus polymerase accessory protein K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain RBD-FIP (PF09457, IPR019018): FIP domain
212	RANBP9	suppressor	15	0.407	16.236	Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator LisH (PF08513, IPR013720, SM00667): LisH SPRY (PF00622, IPR003877, SM00449): SPRY domain CLTH (PF10607, IPR024964): CTLH/CRA C-terminal to LisH motif domain
213	RBL1	suppressor	17	0.382	33.709	RB_A (PF01858, IPR002720): Retinoblastoma-associated protein A domain RB_B (PF01857, IPR002719): Retinoblastoma-associated protein B domain Rb_C (PF08934, IPR015030): Rb C-terminal domain DUF3452 (PF11934, IPR024599): Domain of unknown function (DUF3452)
214	RBX1	oncoprotein	12	0.364	11.872	zf-rbx1 (PF12678, IPR024766): RING-H2 zinc finger domain
215	RCVRN	interactor	2	1.000	0	CytochromB561_N (PF09786, IPR019176): Cytochrome B561, N terminal
216	RELA	oncoprotein	50	0.242	471.641	DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region RHD_DNA_bind (PF00554, IPR011539): Rel homology DNA-binding domain RHD_dimer (PF16179, IPR032397): Rel homology dimerisation domain
217	RGCC	interactor	3	1.000	0	RGCC (PF15151, IPR029252): Response gene to complement 32 protein family
218	RIOK2	interactor	3	0.667	0.143	RIO1 (PF01163, IPR018934): RIO1 family Rio2_N (PF09202, IPR015285): Rio2, N-terminal
219	RNF111	suppressor	10	0.583	5.117	zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain Prok-RING_1 (PF14446): Prokaryotic RING finger family 1 RNF111_N (PF15303, IPR029306): E3 ubiquitin-protein ligase Arkadia N-terminus
220	RNF31	interactor	6	0.400	4.500	Auto_anti-p27 (PF06677, IPR009563): Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) IBR (PF01485, IPR002867, SM00647): IBR domain, a half RING-finger domain PUB (PF09409, IPR018997): PUB domain TF_Zn_Ribbon (PF08271, IPR013137): TFIIB zinc-binding zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others zf-RING_4 (PF14570): RING/Ubox like zinc-binding domain HOIP-UBA (PF16678, IPR032065): UB-associated-like domain of HOIP or E3 ubiquitin-protein ligase
221	RPA1	suppressor	23	0.342	72.989	Rep-A_N (PF04057, IPR007199): Replication factor-A protein 1, N-terminal domain Rep_fac-A_C (PF08646, IPR013955): Replication factor-A C terminal domain tRNA_anti-codon (PF01336, IPR004365): OB-fold nucleic acid binding domain REPA_OB_2 (PF16900, IPR031657): Replication protein A OB domain
222	RPL3	interactor	12	0.636	7.244	Ribosomal_L3 (PF00297, IPR000597): Ribosomal protein L3
223	RPL4	interactor	11	0.655	5.767	Ribosomal_L4 (PF00573, IPR002136): Ribosomal protein L4/L1 family Ribos_L4_asso_C (PF14374, IPR025755): 60S ribosomal protein L4 C-terminal domain
224	RPLP0	interactor	12	0.667	5.884	Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein Ribosomal_L10 (PF00466, IPR001790): Ribosomal protein L10
225	RPSAP15	interactor	2	1.000	0	NA
226	RUNX1	suppressor	26	0.387	64.188	Runt (PF00853, IPR013524): Runt domain RunxI (PF08504, IPR013711): Runx inhibition domain DUF3037 (PF11236, IPR021398): Protein of unknown function (DUF3037)
227	RUNX2	suppressor	25	0.380	63.136	DUF1180 (PF06679, IPR009565): Protein of unknown function (DUF1180) Runt (PF00853, IPR013524): Runt domain TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360) DUF2722 (PF10846, IPR021216): Protein of unknown function (DUF2722)
228	RUNX3	suppressor	14	0.516	11.154	Runt (PF00853, IPR013524): Runt domain RunxI (PF08504, IPR013711): Runx inhibition domain
229	S100A4	interactor	5	0.700	0.750	S_100 (PF01023, IPR013787): S-100/ICaBP type calcium binding domain EF-hand_4 (PF12763, IPR000261): Cytoskeletal-regulatory complex EF hand EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
230	SAP130	interactor	7	0.714	2.114	SAP130_C (PF16014, IPR031963): Histone deacetylase complex subunit SAP130 C-terminus
231	SERTAD1	interactor	11	0.255	27.494	CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal SERTA (PF06031, IPR009263): SERTA motif
232	SETD2	suppressor	3	1.000	0	DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777) SET (PF00856, IPR001214, SM00317): SET domain SRI (PF08236, IPR013257): SRI (Set2 Rpb1 interacting) domain Med26 (PF08711, IPR017923): TFIIS helical bundle-like domain WW (PF00397, IPR001202, SM00456): WW domain DUF3592 (PF12158, IPR021994): Protein of unknown function (DUF3592)
233	SH2D2A	interactor	2	1.000	0	SH2 (PF00017, IPR000980, SM00252): SH2 domain
234	SIK3	oncoprotein	4	0.500	0.784	GET2 (PF08690, IPR028143): GET complex subunit GET2 Pkinase (PF00069, IPR000719): Protein kinase domain Jnk-SapK_ap_N (PF09744, IPR019143): JNK_SAPK-associated protein-1
235	SIN3A	oncoprotein	27	0.311	122.706	Sin3_corepress (PF08295, IPR013194, SM00761): Sin3 family co-repressor PAH (PF02671, IPR003822, SM00309): Paired amphipathic helix repeat Sin3a_C (PF16879, IPR031693): C-terminal domain of Sin3a protein
236	SKI	oncoprotein	29	0.278	134.212	c-SKI_SMAD_bind (PF08782, IPR014890, SM01046): c-SKI Smad4 binding domain Ski_Sno (PF02437, IPR003380): SKI/SNO/DAC family SlyX (PF04102, IPR007236): SlyX HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1
237	SKIL	suppressor	32	0.194	244.312	c-SKI_SMAD_bind (PF08782, IPR014890, SM01046): c-SKI Smad4 binding domain DUF489 (PF04356, IPR007451): Protein of unknown function (DUF489) DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972) Neur_chan_memb (PF02932, IPR006029): Neurotransmitter-gated ion-channel transmembrane region Ski_Sno (PF02437, IPR003380): SKI/SNO/DAC family DUF2115 (PF09888, IPR019215): Uncharacterized protein conserved in archaea (DUF2115)
238	SLC25A12	interactor	5	0.400	2.921	Mito_carr (PF00153, IPR018108): Mitochondrial carrier protein EF-hand_1 (PF00036, IPR002048, SM00054): EF hand EF-hand_6 (PF13405, IPR002048): EF-hand domain EF-hand_7 (PF13499, IPR011992): EF-hand domain pair EF-hand_8 (PF13833, IPR002048): EF-hand domain pair
239	SLC9A3R2	interactor	4	0.500	2.500	EBP50_C (PF09007, IPR015098): EBP50, C-terminal GRASP55_65 (PF04495, IPR024958): GRASP55/65 PDZ-like domain PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
240	SMAD1	interactor	59	0.181	703.609	MH1 (PF03165, IPR003619, SM00523): MH1 domain MH2 (PF03166, IPR001132, SM00524): MH2 domain
241	SMAD2	suppressor	139	0.084	6244.816	MH1 (PF03165, IPR003619, SM00523): MH1 domain MH2 (PF03166, IPR001132, SM00524): MH2 domain
242	SMAD4	suppressor	79	0.140	1503.574	MH1 (PF03165, IPR003619, SM00523): MH1 domain MH2 (PF03166, IPR001132, SM00524): MH2 domain
243	SMAD5	interactor	27	0.313	101.200	MH1 (PF03165, IPR003619, SM00523): MH1 domain MH2 (PF03166, IPR001132, SM00524): MH2 domain
244	SMAD7	interactor	41	0.217	345.841	MH1 (PF03165, IPR003619, SM00523): MH1 domain MH2 (PF03166, IPR001132, SM00524): MH2 domain
245	SMAD9	interactor	27	0.160	202.623	MH1 (PF03165, IPR003619, SM00523): MH1 domain MH2 (PF03166, IPR001132, SM00524): MH2 domain
246	SMARCA4	suppressor	38	0.326	186.880	DUF1840 (PF08895, IPR014991): Domain of unknown function (DUF1840) HSA (PF07529, IPR014012, SM00573): HSA QLQ (PF08880, IPR014978, SM00951): QLQ SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain BRK (PF07533, IPR006576, SM00592): BRK domain Bromodomain (PF00439, IPR001487, SM00297): Bromodomain Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal DUF4065 (PF13274, IPR025272): Protein of unknown function (DUF4065) SnAC (PF14619, IPR029295): Snf2-ATP coupling, chromatin remodelling complex WRNPLPNID (PF15017): Putative WW-binding domain and destruction box
247	SMARCC1	suppressor	27	0.428	52.240	SWIRM (PF04433, IPR007526): SWIRM domain Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain DUF2618 (PF10940, IPR021237): Protein of unknown function (DUF2618) PTPRCAP (PF15713, IPR016553): Protein tyrosine phosphatase receptor type C-associated SWIRM-assoc_1 (PF16495, IPR032451): SWIRM-associated region 1 SWIRM-assoc_2 (PF16496, IPR032450): SWIRM-associated domain at the N-terminal SWIRM-assoc_3 (PF16498, IPR032448): SWIRM-associated domain at the C-terminal
248	SMARCC2	interactor	19	0.421	30.745	GHMP_kinases_N (PF00288, IPR006204): GHMP kinases N terminal domain SWIRM (PF04433, IPR007526): SWIRM domain DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360) Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain SWIRM-assoc_1 (PF16495, IPR032451): SWIRM-associated region 1 SWIRM-assoc_2 (PF16496, IPR032450): SWIRM-associated domain at the N-terminal SWIRM-assoc_3 (PF16498, IPR032448): SWIRM-associated domain at the C-terminal
249	SMURF1	interactor	35	0.230	237.516	C2 (PF00168, IPR000008, SM00239): C2 domain WW (PF00397, IPR001202, SM00456): WW domain HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
250	SMURF2	protein found in more fusions	24	0.379	61.859	C2 (PF00168, IPR000008, SM00239): C2 domain WW (PF00397, IPR001202, SM00456): WW domain HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
251	SNRNP70	interactor	17	0.463	23.253	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MIP-T3 (PF10243): Microtubule-binding protein MIP-T3 U1snRNP70_N (PF12220, IPR022023): U1 small nuclear ribonucleoprotein of 70kDa MW N terminal
252	SNW1	protein found in more fusions	41	0.209	334.929	SKIP_SNW (PF02731, IPR004015): SKIP/SNW domain PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term SIR4_SID (PF16991, IPR031556): Sir4 SID domain
253	SOX9	oncoprotein	6	0.800	0.403	Pex14_N (PF04695, IPR006785): Peroxisomal membrane anchor protein (Pex14p) conserved region TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit HMG_box (PF00505, IPR009071, SM00398): HMG (high mobility group) box Sox_N (PF12444, IPR022151): Sox developmental protein N terminal
254	SP1	protein found in more fusions	47	0.314	307.462	zf-Di19 (PF05605, IPR008598): Drought induced 19 protein (Di19), zinc-binding Herpes_capsid (PF06112, IPR009299): Gammaherpesvirus capsid protein zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type Miga (PF10265, IPR019392): Mitoguardin zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
255	SPTBN1	suppressor	17	0.324	45.703	CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain COG2 (PF06148, IPR024602): COG (conserved oligomeric Golgi) complex component, COG2 DUF1764 (PF08576, IPR013885): Eukaryotic protein of unknown function (DUF1764) Spectrin (PF00435, IPR002017): Spectrin repeat PH_9 (PF15410): Pleckstrin homology domain
256	SQRDL	interactor	5	0.600	0.777	Pyr_redox_2 (PF07992, IPR023753): Pyridine nucleotide-disulphide oxidoreductase
257	SQSTM1	oncoprotein	20	0.287	72.199	PB1 (PF00564, IPR000270, SM00666): PB1 domain ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type UBA_5 (PF16577, IPR015940): UBA domain
258	SREBF2	protein found in more fusions	14	0.308	24.752	HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
259	SRY	interactor	5	0.700	0.736	DUF1908 (PF08926, IPR015022): Domain of unknown function (DUF1908) HMG_box (PF00505, IPR009071, SM00398): HMG (high mobility group) box
260	SS18L1	oncoprotein	10	0.444	5.465	DUF1313 (PF07011, IPR009741): Protein of unknown function (DUF1313) SSXT (PF05030, IPR007726): SSXT protein (N-terminal region)
261	ST6GALNAC2	interactor	1	0	0	Glyco_transf_29 (PF00777, IPR001675): Glycosyltransferase family 29 (sialyltransferase)
262	STRAP	protein found in more fusions	10	0.611	3.337	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
263	STUB1	suppressor	31	0.292	134.577	U-box (PF04564, IPR003613, SM00504): U-box domain ANAPC3 (PF12895): Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 (PF13414, IPR011990): TPR repeat TPR_20 (PF14561): Tetratricopeptide repeat
264	SUV39H1	protein found in more fusions	17	0.358	36.380	Chromo (PF00385, IPR023780, SM00298): Chromo (CHRromatin Organisation MOdifier) domain Pre-SET (PF05033, IPR007728): Pre-SET motif SET (PF00856, IPR001214, SM00317): SET domain
265	SVEP1	interactor	4	0.500	1.389	EGF (PF00008, IPR000742, SM00181): EGF-like domain EGF_2 (PF07974, IPR013111): EGF-like domain EGF_CA (PF07645, IPR001881, SM00179): Calcium-binding EGF domain Ephrin_rec_like (PF07699, IPR011641): Putative ephrin-receptor like HYR (PF02494, IPR003410): HYR domain VWA (PF00092, IPR002035, SM00327): von Willebrand factor type A domain Sushi (PF00084, IPR000436, SM00032): Sushi repeat (SCR repeat) Pentaxin (PF00354, IPR001759, SM00159): Pentaxin family VERL (PF11386, IPR021526): Vitelline envelope receptor for lysin hEGF (PF12661, IPR013032): Human growth factor-like EGF cEGF (PF12662, IPR026823): Complement Clr-like EGF-like
266	TANK	suppressor	7	0.400	6.452	DUF3713 (PF12506, IPR022186): Protein of unknown function (DUF3713) TBD (PF12845, IPR024581): TBD domain
267	TCF12	oncoprotein	10	0.639	5.347	HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
268	TCP1	interactor	16	0.400	25.591	Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
269	TDP2	interactor	4	0.500	1.500	Exo_endo_phos (PF03372, IPR005135): Endonuclease/Exonuclease/phosphatase family DUF4150 (PF13665, IPR025425): Domain of unknown function (DUF4150) UBA_4 (PF14555): UBA-like domain
270	TEKT4	interactor	1	0	0	Tektin (PF03148, IPR000435): Tektin family
271	TF	interactor	3	1.000	0	Transferrin (PF00405, IPR001156, SM00094): Transferrin
272	TFE3	oncoprotein	3	1.000	0	HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain DUF3371 (PF11851, IPR021802): Domain of unknown function (DUF3371) MITF_TFEB_C_3_N (PF15951, IPR031867): MITF/TFEB/TFEC/TFE3 N-terminus
273	TGFB1I1	interactor	7	0.476	5.552	LIM (PF00412, IPR001781, SM00132): LIM domain Paxillin (PF03535): Paxillin family
274	TGFBR1	oncoprotein	19	0.386	39.660	Activin_recp (PF01064, IPR000472): Activin types I and II receptor domain Pkinase (PF00069, IPR000719): Protein kinase domain TGF_beta_GS (PF08515, IPR003605, SM00467): Transforming growth factor beta type I GS-motif
275	TGIF1	oncoprotein	10	0.578	7.050	Homeobox_KN (PF05920, IPR008422): Homeobox KN domain LRS4 (PF10422, IPR018479): Monopolin complex subunit LRS4
276	TGIF2	interactor	2	1.000	0	Homeobox_KN (PF05920, IPR008422): Homeobox KN domain
277	TGM2	protein found in more fusions	11	0.311	21.423	Transglut_C (PF00927, IPR008958): Transglutaminase family, C-terminal ig like domain Transglut_N (PF00868, IPR001102): Transglutaminase family Transglut_core (PF01841, IPR002931, SM00460): Transglutaminase-like superfamily
278	TLR4	interactor	6	0.400	5.750	LRR_1 (PF00560, IPR001611): Leucine Rich Repeat TIR (PF01582, IPR000157, SM00255): TIR domain LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies) LRR_8 (PF13855, IPR001611): Leucine rich repeat LRR_9 (PF14580): Leucine-rich repeat
279	TMED1	interactor	2	1.000	0	EMP24_GP25L (PF01105, IPR009038): emp24/gp25L/p24 family/GOLD
280	TOB1	interactor	9	0.444	7.288	PAM2 (PF07145, IPR009818): Ataxin-2 C-terminal region BTG (PF07742, IPR002087, SM00099): BTG family PRIMA1 (PF16101): Proline-rich membrane anchor 1
281	TP53	suppressor	95	0.166	1865.131	DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region P53 (PF00870, IPR011615): P53 DNA-binding domain P53_tetramer (PF07710, IPR010991): P53 tetramerisation motif
282	TP63	suppressor	21	0.337	59.608	Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region P53 (PF00870, IPR011615): P53 DNA-binding domain P53_tetramer (PF07710, IPR010991): P53 tetramerisation motif SAM_2 (PF07647, IPR011510): SAM domain (Sterile alpha motif)
283	TRIB3	interactor	8	0.393	8.686	Pkinase (PF00069, IPR000719): Protein kinase domain
284	TRIM33	oncoprotein	13	0.439	13.710	PHD (PF00628, IPR019787, SM00249): PHD-finger Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein Siva (PF05458, IPR022773): Cd27 binding protein (Siva) Spectrin (PF00435, IPR002017): Spectrin repeat TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger Bromodomain (PF00439, IPR001487, SM00297): Bromodomain zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger
285	TRIM62	suppressor	3	1.000	0	Laminin_II (PF06009, IPR010307): Laminin Domain II Ribosomal_L37ae (PF01780, IPR002674): Ribosomal L37ae protein family SPRY (PF00622, IPR003877, SM00449): SPRY domain zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger PRY (PF13765, IPR006574, SM00589): SPRY-associated domain DUF3416 (PF11896, IPR021828): Domain of unknown function (DUF3416) Snapin_Pallidin (PF14712, IPR028119): Snapin/Pallidin zf-C3HC4_4 (PF15227): zinc finger of C3HC4-type, RING
286	TSC2	suppressor	8	0.607	2.132	Rap_GAP (PF02145, IPR000331): Rap/ran-GAP Tuberin (PF03542, IPR018515): Tuberin DUF3384 (PF11864, IPR024584): Domain of unknown function (DUF3384) Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1
287	TSC22D4	interactor	8	0.357	13.515	AflR (PF08493, IPR013700): Aflatoxin regulatory protein TSC22 (PF01166, IPR000580): TSC-22/dip/bun family
288	U2AF2	protein found in more fusions	20	0.327	64.413	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Transformer (PF06495, IPR010519): Fruit fly transformer protein
289	UBQLN4	interactor	7	0.467	5.300	CRF (PF00473, IPR000187, SM00039): Corticotropin-releasing factor family DUF1180 (PF06679, IPR009565): Protein of unknown function (DUF1180) Arm_2 (PF04826, IPR006911): Armadillo-like NUDE_C (PF04880, IPR006964): NUDE protein, C-terminal conserved region UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain XPC-binding (PF09280, IPR015360): XPC-binding domain ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family Fur_reg_FbpB (PF13040, IPR025004): Fur-regulated basic protein B partial_CstF (PF15861, IPR031721): Partial cleavage stimulation factor domain
290	UCHL5	oncoprotein	11	0.378	16.799	Peptidase_C12 (PF01088, IPR001578): Ubiquitin carboxyl-terminal hydrolase, family 1
291	USP15	oncoprotein	16	0.514	17.237	UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase DUSP (PF06337, IPR006615, SM00695): DUSP domain Ubiquitin_3 (PF14836, IPR028135): Ubiquitin-like domain
292	USP7	oncoprotein	23	0.190	118.329	MATH (PF00917, IPR002083, SM00061): MATH domain UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase USP7_ICP0_bdg (PF12436, IPR024729): ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 (PF14533, IPR029346): Ubiquitin-specific protease C-terminal
293	USP9X	interactor	11	0.436	12.873	DUF1722 (PF08349, IPR013560): Protein of unknown function (DUF1722) UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase Utp13 (PF08625, IPR013934): Utp13 specific WD40 associated domain
294	VAV2	oncoprotein	3	0.667	0.400	PH (PF00169, IPR001849, SM00233): PH domain RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_2 (PF07653, IPR011511): Variant SH3 domain C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain) CAMSAP_CH (PF11971, IPR022613): CAMSAP CH domain CotJB (PF12652, IPR024207): CotJB protein
295	VDR	suppressor	27	0.363	89.215	zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
296	WWP1	oncoprotein	15	0.429	15.549	C2 (PF00168, IPR000008, SM00239): C2 domain WW (PF00397, IPR001202, SM00456): WW domain HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
297	WWP2	interactor	10	0.417	9.085	WW (PF00397, IPR001202, SM00456): WW domain HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
298	XPO6	interactor	4	0.667	0.583	IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain Xpo1 (PF08389, IPR013598): Exportin 1-like protein
299	XRCC6	oncoprotein	29	0.336	85.443	Ku (PF02735, IPR006164, SM00559): Ku70/Ku80 beta-barrel domain Ku_C (PF03730, IPR005160): Ku70/Ku80 C-terminal arm Ku_N (PF03731, IPR005161): Ku70/Ku80 N-terminal alpha/beta domain SAP (PF02037, IPR003034, SM00513): SAP domain
300	YAP1	suppressor	22	0.260	78.123	Bindin (PF02084, IPR000775): Bindin WW (PF00397, IPR001202, SM00456): WW domain GspL_C (PF12693, IPR025691): GspL periplasmic domain FAM181 (PF15238, IPR029359): FAM181
301	YTHDF2	interactor	6	0.400	3.581	YTH (PF04146, IPR007275): YT521-B-like domain DUF4106 (PF13388, IPR025179): Protein of unknown function (DUF4106)
302	YY1	protein found in more fusions	30	0.310	121.850	zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_4 (PF13894): C2H2-type zinc finger Keratin_2_tail (PF16210, IPR032449): Keratin type II cytoskeletal 1 tail
303	ZBTB16	suppressor	20	0.415	40.371	BTB (PF00651, IPR013069, SM00225): BTB/POZ domain zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_4 (PF13894): C2H2-type zinc finger zf-C2H2_6 (PF13912, IPR007087): C2H2-type zinc finger
304	ZBTB3	interactor	8	0.286	14.571	BTB (PF00651, IPR013069, SM00225): BTB/POZ domain zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_4 (PF13894): C2H2-type zinc finger
305	ZC3H12A	interactor	6	0.600	2.389	RNase_Zc3h12a (PF11977, IPR021869): Zc3h12a-like Ribonuclease NYN domain zf-CCCH_2 (PF14608): RNA-binding, Nab2-type zinc finger
306	ZCCHC14	interactor	3	0.667	1.000	SAM_1 (PF00536, IPR021129, SM00454): SAM domain (Sterile alpha motif) SPX (PF03105, IPR004331): SPX domain zf-CCHC (PF00098, IPR001878): Zinc knuckle
307	ZEB1	interactor	9	0.528	4.360	CDC27 (PF09507, IPR019038): DNA polymerase subunit Cdc27 zf-Di19 (PF05605, IPR008598): Drought induced 19 protein (Di19), zinc-binding GET2 (PF08690, IPR028143): GET complex subunit GET2 Pox_Ag35 (PF03286, IPR004966): Pox virus Ag35 surface protein RNA_pol_Rpc4 (PF05132, IPR007811): RNA polymerase III RPC4 TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type Homeobox (PF00046, IPR001356, SM00389): Homeobox domain zf-C2H2_jaz (PF12171, IPR022755): Zinc-finger double-stranded RNA-binding zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
308	ZEB2	oncoprotein	8	0.500	4.023	zf-Di19 (PF05605, IPR008598): Drought induced 19 protein (Di19), zinc-binding Rep_fac-A_C (PF08646, IPR013955): Replication factor-A C terminal domain Rubredoxin (PF00301, IPR024935): Rubredoxin zf-AN1 (PF01428, IPR000058, SM00154): AN1-like Zinc finger zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type Homeobox (PF00046, IPR001356, SM00389): Homeobox domain zf-C2H2_jaz (PF12171, IPR022755): Zinc-finger double-stranded RNA-binding SpoIIIAH (PF12685, IPR024232): SpoIIIAH-like protein zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_4 (PF13894): C2H2-type zinc finger zf-CCHC_5 (PF14787): GAG-polyprotein viral zinc-finger
309	ZFYVE9	interactor	9	0.528	9.793	FYVE (PF01363, IPR000306, SM00064): FYVE zinc finger SARA (PF11409, IPR024608): Smad anchor for receptor activation (SARA) DUF3480 (PF11979, IPR022557): Domain of unknown function (DUF3480)
310	ZMIZ1	oncoprotein	10	0.489	5.987	zf-MIZ (PF02891, IPR004181): MIZ/SP-RING zinc finger
311	ZMYND11	suppressor	7	0.733	0.763	DUF1002 (PF06207, IPR009343): Protein of unknown function (DUF1002) DUF1353 (PF07087, IPR010767): Protein of unknown function (DUF1353) PWWP (PF00855, IPR000313, SM00293): PWWP domain zf-MYND (PF01753, IPR002893): MYND finger zf-UBR (PF02207, IPR003126): Putative zinc finger in N-recognin (UBR box) Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
312	ZNF329	interactor	2	1.000	0	zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
313	ZNF83	interactor	2	1.000	0	zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain

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