1 |
SLC9A3R1 | parental protein | 75 | 0.069 | 4285.437 | EBP50_C (PF09007, IPR015098): EBP50, C-terminal PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) |
2 |
ABCC2 | interactor | 3 | 0.667 | 1.000 | ABC_membrane (PF00664, IPR001140): ABC transporter transmembrane region ABC_tran (PF00005, IPR003439): ABC transporter DUF805 (PF05656, IPR008523): Protein of unknown function (DUF805) DUF87 (PF01935, IPR002789): Domain of unknown function DUF87 SMC_N (PF02463, IPR003395): RecF/RecN/SMC N terminal domain |
3 |
ABCC4 | interactor | 3 | 1.000 | 0 | ABC_membrane (PF00664, IPR001140): ABC transporter transmembrane region ABC_tran (PF00005, IPR003439): ABC transporter SMC_N (PF02463, IPR003395): RecF/RecN/SMC N terminal domain |
4 |
ADRB2 | interactor | 3 | 1.000 | 0 | 7tm_1 (PF00001, IPR000276): 7 transmembrane receptor (rhodopsin family) |
5 |
AKT1 | oncoprotein | 12 | 0.218 | 36.833 | PH (PF00169, IPR001849, SM00233): PH domain Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain |
6 |
BCL10 | oncoprotein | 3 | 1.000 | 0 | CARD (PF00619, IPR001315, SM00114): Caspase recruitment domain |
7 |
CAPN1 | interactor | 8 | 0.643 | 6.190 | Calpain_III (PF01067, IPR022682, SM00720): Calpain large subunit, domain III Peptidase_C2 (PF00648, IPR001300, SM00230): Calpain family cysteine protease EF-hand_6 (PF13405, IPR002048): EF-hand domain EF-hand_8 (PF13833, IPR002048): EF-hand domain pair |
8 |
CDCA5 | interactor | 2 | 0 | 0 | Sororin (PF09666, IPR018605): Sororin protein |
9 |
CFTR | suppressor | 12 | 0.236 | 38.233 | ABC_membrane (PF00664, IPR001140): ABC transporter transmembrane region ABC_tran (PF00005, IPR003439): ABC transporter Roc (PF08477, IPR013684): Ras of Complex, Roc, domain of DAPkinase SMC_N (PF02463, IPR003395): RecF/RecN/SMC N terminal domain Rotamase_2 (PF13145, IPR000297): PPIC-type PPIASE domain CFTR_R (PF14396, IPR025837): Cystic fibrosis TM conductance regulator (CFTR), regulator domain |
10 |
CKB | interactor | 12 | 0.591 | 14.010 | ATP-gua_Ptrans (PF00217, IPR022414): ATP:guanido phosphotransferase, C-terminal catalytic domain ATP-gua_PtransN (PF02807, IPR022413): ATP:guanido phosphotransferase, N-terminal domain |
11 |
CLCN3 | protein found in more fusions | 4 | 1.000 | 0 | CBS (PF00571, IPR000644, SM00116): CBS domain Voltage_CLC (PF00654, IPR001807): Voltage gated chloride channel |
12 |
CNDP2 | suppressor | 15 | 0.467 | 30.113 | Peptidase_M20 (PF01546, IPR002933): Peptidase family M20/M25/M40 |
13 |
CSE1L | oncoprotein | 14 | 0.473 | 27.591 | CAS_CSE1 (PF03378, IPR005043): CAS/CSE protein, C-terminus Cse1 (PF08506, IPR013713): Cse1 IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain Xpo1 (PF08389, IPR013598): Exportin 1-like protein |
14 |
CTNNB1 | oncoprotein | 9 | 0.528 | 10.967 | Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat Atx10homo_assoc (PF09759, IPR019156): Spinocerebellar ataxia type 10 protein domain DUF3361 (PF11841, IPR024574): Domain of unknown function (DUF3361) HEAT_EZ (PF13513): HEAT-like repeat |
15 |
ECHS1 | protein found in more fusions | 9 | 0.750 | 2.119 | ECH_1 (PF00378, IPR001753): Enoyl-CoA hydratase/isomerase |
16 |
EPHB1 | interactor | 2 | 1.000 | 0 | EGF_2 (PF07974, IPR013111): EGF-like domain fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain Ephrin_rec_like (PF07699, IPR011641): Putative ephrin-receptor like Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SAM_1 (PF00536, IPR021129, SM00454): SAM domain (Sterile alpha motif) Ephrin_lbd (PF01404, IPR001090, SM00615): Ephrin receptor ligand binding domain cEGF (PF12662, IPR026823): Complement Clr-like EGF-like EphA2_TM (PF14575, IPR027936): Ephrin type-A receptor 2 transmembrane domain |
17 |
EZR | protein found in more fusions | 11 | 0.378 | 21.967 | DUF106 (PF01956, IPR002809): Integral membrane protein DUF106 ERM (PF00769, IPR011259): Ezrin/radixin/moesin family FERM_C (PF09380, IPR018980): FERM C-terminal PH-like domain FERM_M (PF00373, IPR019748): FERM central domain FERM_N (PF09379, IPR018979): FERM N-terminal domain |
18 |
FTO | interactor | 6 | 0.800 | 1.400 | FTO_NTD (PF12933, IPR024367): FTO catalytic domain FTO_CTD (PF12934, IPR024366): FTO C-terminal domain |
19 |
G6PD | protein found in more fusions | 12 | 0.673 | 6.991 | G6PD_C (PF02781, IPR022675): Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N (PF00479, IPR022674): Glucose-6-phosphate dehydrogenase, NAD binding domain |
20 |
GDA | interactor | 6 | 0.600 | 4.667 | Amidohydro_1 (PF01979, IPR006680): Amidohydrolase family |
21 |
GNA11 | oncoprotein | 3 | 0.667 | 1.000 | G-alpha (PF00503, IPR001019, SM00275): G-protein alpha subunit |
22 |
IREB2 | interactor | 1 | 0 | 0 | Aconitase (PF00330, IPR001030): Aconitase family (aconitate hydratase) Aconitase_C (PF00694, IPR000573): Aconitase C-terminal domain |
23 |
KCNJ1 | interactor | 2 | 1.000 | 0 | IRK (PF01007, IPR016449): Inward rectifier potassium channel |
24 |
LDHAL6B | interactor | 5 | 0.500 | 3.500 | Ldh_1_C (PF02866, IPR022383): lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N (PF00056, IPR001236): lactate/malate dehydrogenase, NAD binding domain |
25 |
LDHB | interactor | 17 | 0.433 | 42.843 | Ldh_1_C (PF02866, IPR022383): lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N (PF00056, IPR001236): lactate/malate dehydrogenase, NAD binding domain |
26 |
MDH1 | interactor | 6 | 0.400 | 6.900 | Ldh_1_C (PF02866, IPR022383): lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N (PF00056, IPR001236): lactate/malate dehydrogenase, NAD binding domain |
27 |
MME | oncoprotein | 2 | 0 | 0 | Peptidase_M13 (PF01431, IPR018497): Peptidase family M13 Peptidase_M13_N (PF05649, IPR008753): Peptidase family M13 |
28 |
MSN | oncoprotein | 5 | 0.833 | 0.400 | DUF883 (PF05957, IPR010279): Bacterial protein of unknown function (DUF883) ERM (PF00769, IPR011259): Ezrin/radixin/moesin family FERM_C (PF09380, IPR018980): FERM C-terminal PH-like domain FERM_M (PF00373, IPR019748): FERM central domain FERM_N (PF09379, IPR018979): FERM N-terminal domain |
29 |
NANS | interactor | 8 | 0.679 | 3.948 | NeuB (PF03102, IPR013132): NeuB family SAF (PF08666, IPR013974, SM00858): SAF domain |
30 |
NF2 | oncoprotein | 7 | 0.400 | 6.000 | ERM (PF00769, IPR011259): Ezrin/radixin/moesin family FERM_C (PF09380, IPR018980): FERM C-terminal PH-like domain FERM_M (PF00373, IPR019748): FERM central domain FERM_N (PF09379, IPR018979): FERM N-terminal domain |
31 |
NOS2 | interactor | 6 | 0.700 | 2.000 | FAD_binding_1 (PF00667, IPR003097): FAD binding domain Flavodoxin_1 (PF00258, IPR008254): Flavodoxin NAD_binding_1 (PF00175, IPR001433): Oxidoreductase NAD-binding domain NO_synthase (PF02898, IPR004030): Nitric oxide synthase, oxygenase domain |
32 |
NPEPPS | interactor | 14 | 0.516 | 24.138 | Peptidase_M1 (PF01433, IPR014782): Peptidase family M1 ERAP1_C (PF11838, IPR024571): ERAP1-like C-terminal domain |
33 |
NTRK1 | oncoprotein | 28 | 0.239 | 200.465 | I-set (PF07679, IPR013098): Immunoglobulin I-set domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase LRR_8 (PF13855, IPR001611): Leucine rich repeat TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain |
34 |
OPRK1 | interactor | 1 | 0 | 0 | 7tm_1 (PF00001, IPR000276): 7 transmembrane receptor (rhodopsin family) |
35 |
P2RY1 | interactor | 1 | 0 | 0 | 7tm_1 (PF00001, IPR000276): 7 transmembrane receptor (rhodopsin family) |
36 |
PAG1 | protein found in more fusions | 2 | 0 | 0 | PAG (PF15347, IPR032748): Phosphoprotein associated with glycosphingolipid-enriched |
37 |
PALM2 | interactor | 1 | 0 | 0 | Paralemmin (PF03285, IPR004965): Paralemmin Phage_int_SAM_5 (PF13102, IPR025269): Phage integrase SAM-like domain AKAP2_C (PF15304, IPR029304): A-kinase anchor protein 2 C-terminus SUIM_assoc (PF16619): Unstructured region C-term to UIM in Ataxin3 |
38 |
PCYOX1 | interactor | 1 | 0 | 0 | Prenylcys_lyase (PF07156, IPR010795): Prenylcysteine lyase NAD_binding_8 (PF13450): NAD(P)-binding Rossmann-like domain |
39 |
PDGFRA | oncoprotein | 5 | 0.833 | 0.333 | Herpes_gE (PF02480, IPR003404): Alphaherpesvirus glycoprotein E I-set (PF07679, IPR013098): Immunoglobulin I-set domain ig (PF00047, IPR013151, SM00409): Immunoglobulin domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase Ig_3 (PF13927): Immunoglobulin domain LAT (PF15234, IPR008359): Linker for activation of T-cells |
40 |
PDGFRB | oncoprotein | 5 | 0.833 | 0.333 | I-set (PF07679, IPR013098): Immunoglobulin I-set domain ig (PF00047, IPR013151, SM00409): Immunoglobulin domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase V-set (PF07686, IPR013106): Immunoglobulin V-set domain C1-set (PF07654, IPR003597, SM00407): Immunoglobulin C1-set domain Ig_3 (PF13927): Immunoglobulin domain TonB_N (PF16031): TonB N-terminal region |
41 |
PDIA3 | interactor | 11 | 0.491 | 17.815 | Thioredoxin (PF00085, IPR013766): Thioredoxin Thioredoxin_6 (PF13848): Thioredoxin-like domain |
42 |
PDZK1 | interactor | 7 | 0.381 | 12.667 | PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) DUF4265 (PF14085, IPR025361): Domain of unknown function (DUF4265) |
43 |
PHLPP2 | oncoprotein | 2 | 1.000 | 0 | LRR_1 (PF00560, IPR001611): Leucine Rich Repeat PH (PF00169, IPR001849, SM00233): PH domain PP2C (PF00481, IPR001932): Protein phosphatase 2C SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies) LRR_8 (PF13855, IPR001611): Leucine rich repeat IMUP (PF15761, IPR026621): Immortalisation up-regulated protein |
44 |
PLCB1 | oncoprotein | 3 | 1.000 | 0 | DUF1154 (PF06631, IPR009535): Protein of unknown function (DUF1154) DUF913 (PF06025, IPR010314): Domain of Unknown Function (DUF913) EF-hand_like (PF09279, IPR015359): Phosphoinositide-specific phospholipase C, efhand-like PLC-beta_C (PF08703, IPR014815): PLC-beta C terminal PI-PLC-X (PF00388, IPR000909, SM00148): Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y (PF00387, IPR001711, SM00149): Phosphatidylinositol-specific phospholipase C, Y domain DUF3987 (PF13148, IPR025048): Protein of unknown function (DUF3987) zf-C2H2_assoc (PF16606): Unstructured conserved, between two C2H2-type zinc-fingers |
45 |
PPME1 | protein found in more fusions | 7 | 0.667 | 2.122 | Abhydrolase_6 (PF12697, IPR000073): Alpha/beta hydrolase family |
46 |
PPP4R3B | interactor | 9 | 0.611 | 6.486 | Diphtheria_T (PF02764, IPR022405): Diphtheria toxin, T domain SMK-1 (PF04802, IPR006887): Component of IIS longevity pathway SMK-1 IGF2_C (PF08365, IPR013576): Insulin-like growth factor II E-peptide WH1 (PF00568, IPR000697, SM00461): WH1 domain |
47 |
PRKCA | interactor | 8 | 0.619 | 4.133 | C2 (PF00168, IPR000008, SM00239): C2 domain Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain) |
48 |
PTEN | oncoprotein | 10 | 0.289 | 27.833 | DSPc (PF00782, IPR020422, SM00195): Dual specificity phosphatase, catalytic domain PTEN_C2 (PF10409, IPR014020): C2 domain of PTEN tumour-suppressor protein |
49 |
PTH1R | interactor | 1 | 0 | 0 | 7tm_2 (PF00002, IPR000832): 7 transmembrane receptor (Secretin family) HRM (PF02793, IPR001879, SM00008): Hormone receptor domain |
50 |
RACK1 | oncoprotein | 8 | 0.429 | 9.233 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain |
51 |
RNASET2 | interactor | 1 | 0 | 0 | Ribonuclease_T2 (PF00445, IPR001568): Ribonuclease T2 family DHODB_Fe-S_bind (PF10418, IPR019480): Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B |
52 |
RPL23 | interactor | 7 | 0.476 | 8.567 | Ribosomal_L14 (PF00238, IPR000218): Ribosomal protein L14p/L23e |
53 |
RPS3 | interactor | 8 | 0.429 | 11.333 | KH_2 (PF07650, IPR004044): KH domain Ribosomal_S3_C (PF00189, IPR001351): Ribosomal protein S3, C-terminal domain |
54 |
RPS6KA3 | interactor | 7 | 0.714 | 2.848 | Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain |
55 |
SCN4A | interactor | 1 | 0 | 0 | Ion_trans (PF00520, IPR005821): Ion transport protein IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif Na_trans_assoc (PF06512, IPR010526): Sodium ion transport-associated DUF4363 (PF14276, IPR025373): Domain of unknown function (DUF4363) GPHH (PF16905, IPR031649): Voltage-dependent L-type calcium channel, IQ-associated |
56 |
SKP2 | oncoprotein | 4 | 0.500 | 2.667 | LRR_1 (PF00560, IPR001611): Leucine Rich Repeat LRR_2 (PF07723, IPR013101): Leucine Rich Repeat LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies) F-box-like (PF12937, IPR001810): F-box-like LRR_6 (PF13516, IPR001611): Leucine Rich repeat LRR_8 (PF13855, IPR001611): Leucine rich repeat |
57 |
SLC4A7 | interactor | 4 | 0.667 | 1.333 | Band_3_cyto (PF07565, IPR013769): Band 3 cytoplasmic domain HCO3_cotransp (PF00955, IPR011531): HCO3- transporter family OAD_gamma (PF04277, IPR005899): Oxaloacetate decarboxylase, gamma chain DUF2628 (PF10947, IPR024399): Protein of unknown function (DUF2628) FAM176 (PF14851): FAM176 family DUF4519 (PF15012, IPR027960): Domain of unknown function (DUF4519) |
58 |
SLC4A8 | interactor | 1 | 0 | 0 | Band_3_cyto (PF07565, IPR013769): Band 3 cytoplasmic domain HCO3_cotransp (PF00955, IPR011531): HCO3- transporter family Mu-transpos_C (PF09299, IPR015378): Mu transposase, C-terminal |
59 |
SLC9A3 | interactor | 2 | 1.000 | 0 | Na_H_Exchanger (PF00999, IPR006153): Sodium/hydrogen exchanger family NEXCaM_BD (PF16644, IPR032103): Regulatory region of Na+/H+ exchanger NHE binds to calmodulin |
60 |
SMS | interactor | 10 | 0.511 | 14.467 | Spermine_synth (PF01564, IPR001045): Spermine/spermidine synthase |
61 |
TACC1 | interactor | 1 | 0 | 0 | TACC (PF05010, IPR007707): Transforming acidic coiled-coil-containing protein (TACC) DUF4613 (PF15390, IPR028041): Domain of unknown function (DUF4613) |
62 |
TBC1D10A | interactor | 1 | 0 | 0 | LRRCT (PF01463, IPR000483, SM00082): Leucine rich repeat C-terminal domain RabGAP-TBC (PF00566, IPR000195, SM00164): Rab-GTPase-TBC domain TonB_N (PF16031): TonB N-terminal region |
63 |
TCF3 | oncoprotein | 3 | 1.000 | 0 | CDC45 (PF02724, IPR003874): CDC45-like protein HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain DUF3682 (PF12446, IPR022152): Protein of unknown function (DUF3682) |
64 |
TGM2 | protein found in more fusions | 14 | 0.577 | 14.087 | Transglut_C (PF00927, IPR008958): Transglutaminase family, C-terminal ig like domain Transglut_N (PF00868, IPR001102): Transglutaminase family Transglut_core (PF01841, IPR002931, SM00460): Transglutaminase-like superfamily |
65 |
TKFC | interactor | 7 | 0.571 | 5.067 | Dak1 (PF02733, IPR004006): Dak1 domain Dak2 (PF02734, IPR004007, SM01120): DAK2 domain |
66 |
U2AF2 | protein found in more fusions | 8 | 0.524 | 6.300 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Transformer (PF06495, IPR010519): Fruit fly transformer protein |
67 |
UBFD1 | interactor | 9 | 0.833 | 1.635 | ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family |
68 |
UQCRFS1 | interactor | 3 | 0.667 | 1.000 | Rieske (PF00355, IPR017941): Rieske [2Fe-2S] domain Ubiq-Cytc-red_N (PF09165, IPR015248): Ubiquinol-cytochrome c reductase 8 kDa, N-terminal UCR_TM (PF02921, IPR004192): Ubiquinol cytochrome reductase transmembrane region |
69 |
UQCRFS1P1 | interactor | 1 | 0 | 0 | NA |
70 |
YAP1 | oncoprotein | 5 | 0.700 | 2.167 | Bindin (PF02084, IPR000775): Bindin WW (PF00397, IPR001202, SM00456): WW domain GspL_C (PF12693, IPR025691): GspL periplasmic domain FAM181 (PF15238, IPR029359): FAM181 |
71 |
YES1 | oncoprotein | 2 | 1.000 | 0 | Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain YdjC (PF04794, IPR006879): YdjC-like protein SH3_1 (PF00018, IPR001452, SM00326): SH3 domain |
72 |
YWHAB | interactor | 11 | 0.473 | 22.167 | 14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein Virulence_fact (PF13769, IPR025989): Virulence factor |
73 |
YWHAQ | interactor | 16 | 0.433 | 39.961 | 14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein |
74 |
YWHAZ | protein found in more fusions | 15 | 0.418 | 34.734 | 14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein |
75 |
ZNF468 | interactor | 1 | 0 | 0 | DUF1033 (PF06279, IPR010434): Protein of unknown function (DUF1033) KRAB (PF01352, IPR001909, SM00349): KRAB box zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain |