Find Fusion Network

Enter
Fusion ID:
Protein names:


Level of PPIs:
or Upload text file:
Update repository
Visible interactions: all affected independent (normal) missing (in fusions) nothing (blank)

Visualization interactions

Powered by Cytoscape Web for: parental proteins SLC1A3, IFITM1 (from a repository: Mon May 20 04:11:46 2019)
Examples

Cytoscape Web will replace the contents your graph
PPI Properties:

Click on nodes
or edges

Layout Tree
Circle
Radial
Force Directed
Preset
Export graph
PDF file
SVG file
SIF file
XML file
GraphML file

Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)11
The number (and %) of the onco-proteins4 (36.36 %)
The number (and %) of the tumor suppressors0 (0.00 %)
Total number of binary PPIs (saturation %)16 (29.09 %)
The number (and %) of affected PPIs9 (56.25 %)
The number of possible different fusions4
PPI diameter2
PPI radiusinf
The average degree of PPI2.182
Assortativity coefficient-0.8341
The network average Clustering coefficient0.318
The number (and %) of a zero Clustering coefficients7 (63.64 %)
The number (and %) of a zero Betweenness Centrality9 (81.82 %)

ACTIVE INTERACTORS
MISSING INTERACTORS (in fusions)


List of the fusions

PPI for parental proteins: SLC1A3,IFITM1 All fusions
: AW888966;
Proteins found in more fusions ZDHHC17 (see 2 fusions); CUL3 (see 1 fusions); LGALS3 (see 2 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 SLC1A3parental protein5020.000SDF (PF00375, IPR001991): Sodium:dicarboxylate symporter family
2 IFITM1parental protein40.5006.000CD225 (PF04505, IPR007593): Interferon-induced transmembrane protein
3 ABHD16Ainteractor100Abhydrolase_1 (PF00561, IPR000073): alpha/beta hydrolase fold
Abhydrolase_6 (PF12697, IPR000073): Alpha/beta hydrolase family
4 CD19interactor31.0000V-set (PF07686, IPR013106): Immunoglobulin V-set domain
Ig_3 (PF13927): Immunoglobulin domain
5 CD81interactor41.0000Tetraspannin (PF00335, IPR018499): Tetraspanin family
6 CR2oncoprotein31.0000C_tripleX (PF02363, IPR003341): Cysteine rich repeat
UL45 (PF05473, IPR008646): UL45 protein, carbohydrate-binding C-type lectin-like
TIL (PF01826, IPR002919): Trypsin Inhibitor like cysteine rich domain
Sushi (PF00084, IPR000436, SM00032): Sushi repeat (SCR repeat)
7 CUL3protein found in more fusions200Cullin (PF00888, IPR001373, SM00182): Cullin family
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
WAC_Acf1_DNA_bd (PF10537, IPR013136): ATP-utilising chromatin assembly and remodelling N-terminal
8 LGALS3oncoprotein200Gal-bind_lectin (PF00337, IPR001079, SM00908): Galactoside-binding lectin
9 TCTN3interactor100DUF1619 (PF07773, IPR011677): Protein of unknown function (DUF1619)
10 TMEM17interactor100Transmemb_17 (PF09799, IPR019184): Predicted membrane protein
DUF3043 (PF11241, IPR021403): Protein of unknown function (DUF3043)
11 ZDHHC17protein found in more fusions200zf-DHHC (PF01529, IPR001594): DHHC palmitoyltransferase
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
Ank_3 (PF13606, IPR002110): Ankyrin repeat
Ank_4 (PF13637): Ankyrin repeats (many copies)

B a c k    t o    T o p ⇑


List of missing interactors (in fusions)

# Name Type Domains (Pfam, InterPro, SMART): description Fusion(s)
1 CD81interactorTetraspannin (PF00335, IPR018499): Tetraspanin familyAW888966
2 CUL3interactorCullin (PF00888, IPR001373, SM00182): Cullin family
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
WAC_Acf1_DNA_bd (PF10537, IPR013136): ATP-utilising chromatin assembly and remodelling N-terminal
AW888966
3 IFITM1parental proteinCD225 (PF04505, IPR007593): Interferon-induced transmembrane proteinAW888966
4 LGALS3oncoproteinGal-bind_lectin (PF00337, IPR001079, SM00908): Galactoside-binding lectinAW888966
5 SLC1A3parental proteinSDF (PF00375, IPR001991): Sodium:dicarboxylate symporter familyAW888966
6 TCTN3interactorDUF1619 (PF07773, IPR011677): Protein of unknown function (DUF1619)AW888966
7 TMEM17interactorTransmemb_17 (PF09799, IPR019184): Predicted membrane protein
DUF3043 (PF11241, IPR021403): Protein of unknown function (DUF3043)
AW888966
8 ZDHHC17interactorzf-DHHC (PF01529, IPR001594): DHHC palmitoyltransferase
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
Ank_3 (PF13606, IPR002110): Ankyrin repeat
Ank_4 (PF13637): Ankyrin repeats (many copies)
AW888966

B a c k    t o    T o p ⇑