1 |
SKI | parental protein | 120 | 0.073 | 9743.164 | c-SKI_SMAD_bind (PF08782, IPR014890, SM01046): c-SKI Smad4 binding domain Ski_Sno (PF02437, IPR003380): SKI/SNO/DAC family SlyX (PF04102, IPR007236): SlyX HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1 |
2 |
ACTB | oncoprotein | 10 | 0.639 | 3.697 | Actin (PF00022, IPR004000, SM00268): Actin |
3 |
ACTBL2 | interactor | 2 | 1.000 | 0 | Actin (PF00022, IPR004000, SM00268): Actin |
4 |
AGRN | interactor | 1 | 0 | 0 | EGF (PF00008, IPR000742, SM00181): EGF-like domain Kazal_1 (PF00050, IPR002350): Kazal-type serine protease inhibitor domain Laminin_G_1 (PF00054, IPR001791): Laminin G domain NtA (PF03146, IPR004850): Agrin NtA domain SEA (PF01390, IPR000082, SM00200): SEA domain Laminin_EGF (PF00053, IPR002049, SM00180): Laminin EGF domain Kazal_2 (PF07648, IPR002350, SM00280): Kazal-type serine protease inhibitor domain hEGF (PF12661, IPR013032): Human growth factor-like EGF EGF_3 (PF12947, IPR024731): EGF domain |
5 |
AHNAK | suppressor | 6 | 0.500 | 1.136 | DUF945 (PF06097, IPR010352): Bacterial protein of unknown function (DUF945) ELFV_dehydrog_N (PF02812, IPR006097): Glu/Leu/Phe/Val dehydrogenase, dimerisation domain T2SSN (PF01203, IPR022792): Type II secretion system (T2SS), protein N PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) TT_ORF2a (PF08197, IPR013267): pORF2a truncated protein DUF2993 (PF11209, IPR021373): Protein of unknown function (DUF2993) DUF4097 (PF13349, IPR025164): Putative adhesin Ntox37 (PF15535, IPR029108): Bacterial toxin 37 |
6 |
AKT1 | oncoprotein | 20 | 0.310 | 67.494 | PH (PF00169, IPR001849, SM00233): PH domain Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain |
7 |
AKT2 | oncoprotein | 3 | 1.000 | 0 | PH (PF00169, IPR001849, SM00233): PH domain Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain |
8 |
ATP1A1 | interactor | 5 | 0.600 | 2.167 | Cation_ATPase_C (PF00689, IPR006068): Cation transporting ATPase, C-terminus Cation_ATPase_N (PF00690, IPR004014, SM00831): Cation transporter/ATPase, N-terminus E1-E2_ATPase (PF00122, IPR008250): E1-E2 ATPase Hydrolase_3 (PF08282, IPR023214): haloacid dehalogenase-like hydrolase Tetraspannin (PF00335, IPR018499): Tetraspanin family Cation_ATPase (PF13246): Cation transport ATPase (P-type) |
9 |
ATP2A2 | interactor | 1 | 0 | 0 | Cation_ATPase_C (PF00689, IPR006068): Cation transporting ATPase, C-terminus Cation_ATPase_N (PF00690, IPR004014, SM00831): Cation transporter/ATPase, N-terminus E1-E2_ATPase (PF00122, IPR008250): E1-E2 ATPase Hydrolase_3 (PF08282, IPR023214): haloacid dehalogenase-like hydrolase HAD (PF12710): haloacid dehalogenase-like hydrolase Cation_ATPase (PF13246): Cation transport ATPase (P-type) |
10 |
ATP5A1 | protein found in more fusions | 12 | 0.491 | 15.248 | ATP-synt_ab (PF00006, IPR000194): ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C (PF00306, IPR000793): ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N (PF02874, IPR004100): ATP synthase alpha/beta family, beta-barrel domain |
11 |
ATP5B | interactor | 10 | 0.511 | 12.164 | AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA) ATP-synt_ab (PF00006, IPR000194): ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N (PF02874, IPR004100): ATP synthase alpha/beta family, beta-barrel domain NACHT (PF05729): NACHT domain |
12 |
ATP5O | interactor | 4 | 1.000 | 0 | OSCP (PF00213, IPR000711): ATP synthase delta (OSCP) subunit |
13 |
AXIN1 | suppressor | 6 | 0.800 | 0.429 | Axin_b-cat_bind (PF08833, IPR014936): Axin beta-catenin binding domain RGS (PF00615, IPR000342, SM00315): Regulator of G protein signaling domain DIX (PF00778, IPR001158, SM00021): DIX domain AXIN1_TNKS_BD (PF16646, IPR032101): Axin-1 tankyrase binding domain |
14 |
CAD | oncoprotein | 13 | 0.359 | 29.184 | Amidohydro_1 (PF01979, IPR006680): Amidohydrolase family CPSase_L_D2 (PF02786, IPR005479): Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 (PF02787, IPR005480, SM01096): Carbamoyl-phosphate synthetase large chain, oligomerisation domain CPSase_sm_chain (PF00988, IPR002474, SM01097): Carbamoyl-phosphate synthase small chain, CPSase domain GATase (PF00117, IPR017926): Glutamine amidotransferase class-I MGS (PF02142, IPR011607, SM00851): MGS-like domain OTCace (PF00185, IPR006131): Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N (PF02729, IPR006132): Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain ATPgrasp_Ter (PF15632, IPR011226): ATP-grasp in the biosynthetic pathway with Ter operon |
15 |
CCT3 | interactor | 10 | 0.444 | 14.119 | Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family |
16 |
COPB1 | protein found in more fusions | 6 | 0.600 | 2.556 | Adaptin_N (PF01602, IPR002553): Adaptin N terminal region Coatamer_beta_C (PF07718, IPR011710): Coatomer beta C-terminal region Coatomer_b_Cpla (PF14806, IPR029446): Coatomer beta subunit appendage platform |
17 |
DCAF7 | interactor | 10 | 0.444 | 18.267 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat |
18 |
DDX5 | oncoprotein | 13 | 0.530 | 15.041 | DEAD (PF00270, IPR011545): DEAD/DEAH box helicase P68HR (PF08061, IPR012587): P68HR (NUC004) repeat ResIII (PF04851, IPR006935): Type III restriction enzyme, res subunit Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain |
19 |
DIAPH1 | interactor | 4 | 0.667 | 1.286 | APG6 (PF04111, IPR007243): Autophagy protein Apg6 Drf_DAD (PF06345, IPR010465): DRF Autoregulatory Domain Drf_FH1 (PF06346, IPR009408): Formin Homology Region 1 Drf_FH3 (PF06367, IPR010472, SM01139): Diaphanous FH3 Domain Drf_GBD (PF06371, IPR010473, SM01140): Diaphanous GTPase-binding Domain FH2 (PF02181, IPR015425, SM00498): Formin Homology 2 Domain Glucan_synthase (PF02364, IPR003440): 1,3-beta-glucan synthase component Neur_chan_memb (PF02932, IPR006029): Neurotransmitter-gated ion-channel transmembrane region |
20 |
DYNC1H1 | interactor | 6 | 0.400 | 5.317 | AAA_5 (PF07728, IPR011704): AAA domain (dynein-related subfamily) DHC_N1 (PF08385, IPR013594): Dynein heavy chain, N-terminal region 1 DHC_N2 (PF08393, IPR013602): Dynein heavy chain, N-terminal region 2 DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664) DUF948 (PF06103, IPR009293): Bacterial protein of unknown function (DUF948) Dynein_heavy (PF03028, IPR004273): Dynein heavy chain and region D6 of dynein motor Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family AAA_6 (PF12774): Hydrolytic ATP binding site of dynein motor region D1 AAA_7 (PF12775): P-loop containing dynein motor region D3 MT (PF12777, IPR024743): Microtubule-binding stalk of dynein motor AAA_8 (PF12780, IPR024317): P-loop containing dynein motor region D4 AAA_9 (PF12781): ATP-binding dynein motor region D5 |
21 |
DYRK1B | oncoprotein | 6 | 0.600 | 1.900 | Pkinase (PF00069, IPR000719): Protein kinase domain |
22 |
EPPK1 | interactor | 4 | 0.500 | 1.000 | DUF1840 (PF08895, IPR014991): Domain of unknown function (DUF1840) HupF_HypC (PF01455, IPR001109): HupF/HypC family Plectin (PF00681, IPR001101, SM00250): Plectin repeat RPA_interact_N (PF14766, IPR028158): Replication protein A interacting N-terminal |
23 |
ESR1 | suppressor | 42 | 0.235 | 392.778 | Oest_recep (PF02159, IPR001292): Oestrogen receptor zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor ESR1_C (PF12743, IPR024736): Oestrogen-type nuclear receptor final C-terminal |
24 |
EYA3 | interactor | 1 | 0 | 0 | NA |
25 |
GATA1 | oncoprotein | 5 | 0.800 | 0.786 | GATA (PF00320, IPR000679, SM00401): GATA zinc finger Vps36-NZF-N (PF16988, IPR031558): Vacuolar protein sorting 36 NZF-N zinc-finger domain |
26 |
GLI2 | oncoprotein | 1 | 0 | 0 | zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_4 (PF13894): C2H2-type zinc finger FOXP-CC (PF16159, IPR032354): FOXP coiled-coil domain |
27 |
GLI3 | oncoprotein | 2 | 1.000 | 0 | zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain FOXP-CC (PF16159, IPR032354): FOXP coiled-coil domain |
28 |
HADHA | interactor | 3 | 1.000 | 0 | 3HCDH (PF00725, IPR006108): 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 3HCDH_N (PF02737, IPR006176): 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ECH_1 (PF00378, IPR001753): Enoyl-CoA hydratase/isomerase |
29 |
HADHB | interactor | 7 | 0.524 | 7.389 | Thiolase_C (PF02803, IPR020617): Thiolase, C-terminal domain Thiolase_N (PF00108, IPR020616): Thiolase, N-terminal domain |
30 |
HDAC3 | suppressor | 20 | 0.322 | 66.074 | Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain |
31 |
HIPK2 | suppressor | 16 | 0.400 | 40.648 | Kdo (PF06293, IPR010440): Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase (PF00069, IPR000719): Protein kinase domain |
32 |
HNRNPM | interactor | 15 | 0.562 | 22.361 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HnRNP_M (PF11532, IPR024666): Heterogeneous nuclear ribonucleoprotein M Collagen_mid (PF15984, IPR031929): Bacterial collagen, middle region |
33 |
HSP90AB1 | oncoprotein | 23 | 0.312 | 90.766 | HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HSP90 (PF00183, IPR001404): Hsp90 protein |
34 |
HSPA1L | interactor | 7 | 0.714 | 2.452 | HSP70 (PF00012, IPR013126): Hsp70 protein |
35 |
HSPA5 | oncoprotein | 20 | 0.368 | 54.805 | HSP70 (PF00012, IPR013126): Hsp70 protein |
36 |
HSPA6 | interactor | 5 | 0.900 | 0.400 | HSP70 (PF00012, IPR013126): Hsp70 protein |
37 |
HSPA8 | oncoprotein | 19 | 0.427 | 44.187 | HSP70 (PF00012, IPR013126): Hsp70 protein |
38 |
HSPA9 | oncoprotein | 9 | 0.417 | 10.112 | HSP70 (PF00012, IPR013126): Hsp70 protein |
39 |
HSPD1 | suppressor | 8 | 0.679 | 2.167 | Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family |
40 |
HSPG2 | oncoprotein | 1 | 0 | 0 | C2-set (PF05790, IPR008424): Immunoglobulin C2-set domain EGF (PF00008, IPR000742, SM00181): EGF-like domain I-set (PF07679, IPR013098): Immunoglobulin I-set domain Laminin_B (PF00052, IPR000034): Laminin B (Domain IV) Laminin_G_1 (PF00054, IPR001791): Laminin G domain V-set (PF07686, IPR013106): Immunoglobulin V-set domain Laminin_EGF (PF00053, IPR002049, SM00180): Laminin EGF domain Ldl_recept_a (PF00057, IPR002172, SM00192): Low-density lipoprotein receptor domain class A hEGF (PF12661, IPR013032): Human growth factor-like EGF Ig_2 (PF13895, IPR007110): Immunoglobulin domain Ig_3 (PF13927): Immunoglobulin domain Izumo-Ig (PF16706, IPR032699): Izumo-like Immunoglobulin domain |
41 |
ITGB4 | oncoprotein | 4 | 0.667 | 1.000 | Calx-beta (PF03160, IPR003644, SM00237): Calx-beta domain EGF_2 (PF07974, IPR013111): EGF-like domain fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain Integrin_B_tail (PF07965, IPR012896): Integrin beta tail domain SEA (PF01390, IPR000082, SM00200): SEA domain STOP (PF05217, IPR024963): STOP protein Integrin_beta (PF00362, IPR002369, SM00187): Integrin, beta chain PSI_integrin (PF17205): Integrin plexin domain |
42 |
JUN | oncoprotein | 18 | 0.412 | 37.236 | bZIP_1 (PF00170, IPR004827): bZIP transcription factor Jun (PF03957, IPR005643): Jun-like transcription factor |
43 |
LATS2 | suppressor | 9 | 0.393 | 13.900 | Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain |
44 |
LDHA | protein found in more fusions | 8 | 0.381 | 7.233 | Ldh_1_C (PF02866, IPR022383): lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N (PF00056, IPR001236): lactate/malate dehydrogenase, NAD binding domain |
45 |
LTBR | oncoprotein | 2 | 0 | 0 | Ephrin_rec_like (PF07699, IPR011641): Putative ephrin-receptor like TNFR_c6 (PF00020, IPR001368, SM00208): TNFR/NGFR cysteine-rich region TMEM252 (PF15664, IPR031363): Transmembrane protein 252 family |
46 |
MECP2 | interactor | 5 | 0.600 | 1.619 | K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain MBD (PF01429, IPR001739, SM00391): Methyl-CpG binding domain SelP_N (PF04592, IPR007671): Selenoprotein P, N terminal region IHABP4_N (PF16174, IPR032381): Intracellular hyaluronan-binding protein 4 N-terminal |
47 |
MERTK | oncoprotein | 2 | 0 | 0 | fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain ig (PF00047, IPR013151, SM00409): Immunoglobulin domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase Ig_3 (PF13927): Immunoglobulin domain |
48 |
MOB1A | suppressor | 6 | 0.667 | 3.333 | Mob1_phocein (PF03637, IPR005301): Mob1/phocein family |
49 |
MOB1B | suppressor | 6 | 0.667 | 3.333 | Mob1_phocein (PF03637, IPR005301): Mob1/phocein family |
50 |
MVP | oncoprotein | 8 | 0.619 | 3.071 | Vault (PF01505, IPR002499): Major Vault Protein repeat DUF2543 (PF10820, IPR020251): Protein of unknown function (DUF2543) MVP_shoulder (PF11978, IPR021870): Shoulder domain |
51 |
MYB | oncoprotein | 10 | 0.467 | 12.200 | Cmyb_C (PF09316, IPR015395): C-myb, C-terminal LMSTEN (PF07988, IPR012642): LMSTEN motif Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain |
52 |
NCL | protein found in more fusions | 13 | 0.621 | 14.789 | DUF1754 (PF08555, IPR013865): Eukaryotic family of unknown function (DUF1754) Myc_N (PF01056, IPR012682): Myc amino-terminal region RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) YL1 (PF05764, IPR008895): YL1 nuclear protein Limkain-b1 (PF11608, IPR024582): Limkain b1 |
53 |
NCOR1 | oncoprotein | 19 | 0.409 | 55.149 | BES1_N (PF05687, IPR008540): BES1/BZR1 plant transcription factor, N-terminal Lamp (PF01299, IPR002000): Lysosome-associated membrane glycoprotein (Lamp) MAS20 (PF02064, IPR002056): MAS20 protein import receptor Neur_chan_memb (PF02932, IPR006029): Neurotransmitter-gated ion-channel transmembrane region Eapp_C (PF10238, IPR019370): E2F-associated phosphoprotein Hid1 (PF12722): High-temperature-induced dauer-formation protein Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain DUF3915 (PF13054, IPR025026): Protein of unknown function (DUF3915) GPS2_interact (PF15784, IPR031557): G-protein pathway suppressor 2-interacting domain DUF4834 (PF16118, IPR032272): Domain of unknown function (DUF4834) RBR (PF17208): RNA binding Region |
54 |
NFIX | oncoprotein | 5 | 0.833 | 0.333 | CTF_NFI (PF00859, IPR000647): CTF/NF-I family transcription modulation region NfI_DNAbd_pre-N (PF10524, IPR019548): Nuclear factor I protein pre-N-terminus MH1 (PF03165, IPR003619, SM00523): MH1 domain |
55 |
NLK | protein found in more fusions | 6 | 0.600 | 1.283 | Pkinase (PF00069, IPR000719): Protein kinase domain SelP_N (PF04592, IPR007671): Selenoprotein P, N terminal region TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit |
56 |
PABPC1 | oncoprotein | 16 | 0.629 | 13.853 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP (PF00658, IPR002004, SM00517): Poly-adenylate binding protein, unique domain YflT (PF11181, IPR025889): Heat induced stress protein YflT |
57 |
PABPC4 | interactor | 4 | 0.500 | 2.333 | ApbA_C (PF08546, IPR013752): Ketopantoate reductase PanE/ApbA C terminal RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP (PF00658, IPR002004, SM00517): Poly-adenylate binding protein, unique domain HHV-5_US34A (PF17087, IPR031384): Herpesvirus US34A protein family |
58 |
PCNA | oncoprotein | 5 | 0.667 | 0.833 | PCNA_C (PF02747, IPR022649): Proliferating cell nuclear antigen, C-terminal domain PCNA_N (PF00705, IPR022648): Proliferating cell nuclear antigen, N-terminal domain |
59 |
PFKP | interactor | 2 | 1.000 | 0 | PFK (PF00365, IPR000023): Phosphofructokinase Hrs_helical (PF12210, IPR024641): Hepatocyte growth factor-regulated tyrosine kinase substrate |
60 |
PLEC | oncoprotein | 4 | 0.500 | 1.100 | CDC37_N (PF03234, IPR013855, SM01071): Cdc37 N terminal kinase binding CENP-H (PF05837, IPR008426): Centromere protein H (CENP-H) CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972) Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family FUSC (PF04632, IPR006726): Fusaric acid resistance protein family RNA_pol_Rbc25 (PF08292, IPR013238): RNA polymerase III subunit Rpc25 S10_plectin (PF03501, IPR005326): Plectin/S10 domain Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein DUF2229 (PF09989, IPR018709): CoA enzyme activase uncharacterised domain (DUF2229) Plectin (PF00681, IPR001101, SM00250): Plectin repeat YlqD (PF11068, IPR021297): YlqD protein Alanine_zipper (PF11839, IPR021793): Alanine-zipper, major outer membrane lipoprotein DUF3391 (PF11871, IPR021812): Domain of unknown function (DUF3391) DUF4140 (PF13600, IPR025554): N-terminal domain of unknown function (DUF4140) |
61 |
PML | suppressor | 22 | 0.390 | 68.576 | zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger DUF3583 (PF12126, IPR021978): Protein of unknown function (DUF3583) zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger) |
62 |
PPM1B | interactor | 2 | 1.000 | 0 | PP2C (PF00481, IPR001932): Protein phosphatase 2C PP2C_C (PF07830, IPR012911, SM00332): Protein serine/threonine phosphatase 2C, C-terminal domain |
63 |
PRDM16 | oncoprotein | 3 | 1.000 | 0 | SET (PF00856, IPR001214, SM00317): SET domain zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_6 (PF13912, IPR007087): C2H2-type zinc finger |
64 |
PRDX1 | oncoprotein | 3 | 1.000 | 0 | AhpC-TSA (PF00578, IPR000866): AhpC/TSA family 1-cysPrx_C (PF10417, IPR019479): C-terminal domain of 1-Cys peroxiredoxin |
65 |
PRKDC | protein found in more fusions | 16 | 0.448 | 36.048 | FAT (PF02259, IPR003151): FAT domain FATC (PF02260, IPR003152): FATC domain NUC194 (PF08163, IPR012582): NUC194 domain PI3_PI4_kinase (PF00454, IPR000403, SM00146): Phosphatidylinositol 3- and 4-kinase |
66 |
PRMT5 | protein found in more fusions | 6 | 0.600 | 2.800 | PRMT5 (PF05185, IPR025799): PRMT5 arginine-N-methyltransferase |
67 |
PYGB | protein found in more fusions | 2 | 0 | 0 | Phosphorylase (PF00343, IPR000811): Carbohydrate phosphorylase |
68 |
RACK1 | suppressor | 12 | 0.564 | 12.282 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain |
69 |
RANBP9 | suppressor | 13 | 0.424 | 26.065 | Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator LisH (PF08513, IPR013720, SM00667): LisH SPRY (PF00622, IPR003877, SM00449): SPRY domain CLTH (PF10607, IPR024964): CTLH/CRA C-terminal to LisH motif domain |
70 |
RARA | oncoprotein | 11 | 0.533 | 8.536 | zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor |
71 |
RB1 | suppressor | 13 | 0.423 | 25.010 | RB_A (PF01858, IPR002720): Retinoblastoma-associated protein A domain RB_B (PF01857, IPR002719): Retinoblastoma-associated protein B domain Rb_C (PF08934, IPR015030): Rb C-terminal domain DUF3452 (PF11934, IPR024599): Domain of unknown function (DUF3452) DUF4592 (PF15262, IPR028030): Domain of unknown function (DUF4592) |
72 |
RB1CC1 | suppressor | 4 | 0.667 | 0.429 | Arc_PepC_II (PF06847, IPR009655): Archaeal Peptidase A24 C-terminus Type II DHC (PF09626, IPR018588): Dihaem cytochrome c DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972) FlaC_arch (PF05377, IPR008039): Flagella accessory protein C (FlaC) ATG11 (PF10377, IPR019460): Autophagy-related protein 11 DUF4407 (PF14362, IPR025519): Domain of unknown function (DUF4407) Jag_N (PF14804, IPR032782): Jag N-terminus NPBW (PF15180, IPR013297): Neuropeptides B and W HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1 BST2 (PF16716, IPR024886): Bone marrow stromal antigen 2 Goodbye (PF17109, IPR031350): fungal STAND N-terminal Goodbye domain |
73 |
RNF111 | suppressor | 9 | 0.607 | 4.448 | zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain Prok-RING_1 (PF14446): Prokaryotic RING finger family 1 RNF111_N (PF15303, IPR029306): E3 ubiquitin-protein ligase Arkadia N-terminus |
74 |
RPL12 | interactor | 14 | 0.802 | 5.832 | Ribosomal_L11 (PF00298, IPR020783): Ribosomal protein L11, RNA binding domain Ribosomal_L11_N (PF03946, IPR020784): Ribosomal protein L11, N-terminal domain |
75 |
RPL14 | interactor | 17 | 0.699 | 12.974 | KOW (PF00467, IPR005824, SM00739): KOW motif Ribosomal_L14e (PF01929, IPR002784): Ribosomal protein L14 UPF0688 (PF15772, IPR031530): UPF0688 family |
76 |
RPL18 | interactor | 19 | 0.561 | 42.906 | Ribosomal_L18 (PF17135): Ribosomal protein 60S L18 and 50S L18e |
77 |
RPL30 | interactor | 11 | 0.964 | 0.400 | NCBP3 (PF10309, IPR019416): Nuclear cap-binding protein subunit 3 |
78 |
RPL4 | interactor | 18 | 0.614 | 26.581 | Ribosomal_L4 (PF00573, IPR002136): Ribosomal protein L4/L1 family Ribos_L4_asso_C (PF14374, IPR025755): 60S ribosomal protein L4 C-terminal domain |
79 |
RPLP0 | interactor | 17 | 0.691 | 12.487 | Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein Ribosomal_L10 (PF00466, IPR001790): Ribosomal protein L10 |
80 |
RPS16 | interactor | 19 | 0.602 | 25.450 | Ribosomal_S9 (PF00380, IPR000754): Ribosomal protein S9/S16 |
81 |
RPS3 | interactor | 18 | 0.542 | 32.472 | KH_2 (PF07650, IPR004044): KH domain Ribosomal_S3_C (PF00189, IPR001351): Ribosomal protein S3, C-terminal domain |
82 |
RPS4X | interactor | 17 | 0.713 | 11.081 | KOW (PF00467, IPR005824, SM00739): KOW motif Ribosomal_S4e (PF00900, IPR013845): Ribosomal family S4e RS4NT (PF08071, IPR013843): RS4NT (NUC023) domain S4 (PF01479, IPR002942, SM00363): S4 domain 40S_S4_C (PF16121, IPR032277): 40S ribosomal protein S4 C-terminus |
83 |
SAV1 | oncoprotein | 5 | 0.800 | 1.333 | WW (PF00397, IPR001202, SM00456): WW domain |
84 |
SIAH2 | oncoprotein | 6 | 0.800 | 0.848 | Sina (PF03145, IPR018121): Seven in absentia protein family zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger) |
85 |
SIN3A | oncoprotein | 13 | 0.474 | 21.213 | Sin3_corepress (PF08295, IPR013194, SM00761): Sin3 family co-repressor PAH (PF02671, IPR003822, SM00309): Paired amphipathic helix repeat Sin3a_C (PF16879, IPR031693): C-terminal domain of Sin3a protein |
86 |
SIRT1 | suppressor | 18 | 0.412 | 41.410 | DUF592 (PF04574, IPR007654): Protein of unknown function (DUF592) SIR2 (PF02146, IPR003000): Sir2 family TPP_enzyme_M (PF00205, IPR012000): Thiamine pyrophosphate enzyme, central domain |
87 |
SIX1 | oncoprotein | 1 | 0 | 0 | KilA-N (PF04383, IPR018004): KilA-N domain Homeobox (PF00046, IPR001356, SM00389): Homeobox domain SIX1_SD (PF16878, IPR031701): Transcriptional regulator, SIX1, N-terminal SD domain |
88 |
SKIL | suppressor | 18 | 0.419 | 38.324 | c-SKI_SMAD_bind (PF08782, IPR014890, SM01046): c-SKI Smad4 binding domain DUF489 (PF04356, IPR007451): Protein of unknown function (DUF489) DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972) Neur_chan_memb (PF02932, IPR006029): Neurotransmitter-gated ion-channel transmembrane region Ski_Sno (PF02437, IPR003380): SKI/SNO/DAC family DUF2115 (PF09888, IPR019215): Uncharacterized protein conserved in archaea (DUF2115) |
89 |
SLC25A13 | interactor | 1 | 0 | 0 | Mito_carr (PF00153, IPR018108): Mitochondrial carrier protein EF-hand_6 (PF13405, IPR002048): EF-hand domain EF-hand_7 (PF13499, IPR011992): EF-hand domain pair EF-hand_8 (PF13833, IPR002048): EF-hand domain pair |
90 |
SLC25A4 | interactor | 2 | 1.000 | 0 | Mito_carr (PF00153, IPR018108): Mitochondrial carrier protein |
91 |
SLC25A5 | interactor | 10 | 0.711 | 10.200 | Mito_carr (PF00153, IPR018108): Mitochondrial carrier protein |
92 |
SLC25A6 | interactor | 2 | 1.000 | 0 | Mito_carr (PF00153, IPR018108): Mitochondrial carrier protein |
93 |
SMAD1 | interactor | 10 | 0.611 | 9.412 | MH1 (PF03165, IPR003619, SM00523): MH1 domain MH2 (PF03166, IPR001132, SM00524): MH2 domain |
94 |
SMAD2 | suppressor | 26 | 0.263 | 144.644 | MH1 (PF03165, IPR003619, SM00523): MH1 domain MH2 (PF03166, IPR001132, SM00524): MH2 domain |
95 |
SMAD3 | oncoprotein | 29 | 0.278 | 163.415 | MH1 (PF03165, IPR003619, SM00523): MH1 domain MH2 (PF03166, IPR001132, SM00524): MH2 domain |
96 |
SMAD4 | suppressor | 15 | 0.429 | 29.397 | MH1 (PF03165, IPR003619, SM00523): MH1 domain MH2 (PF03166, IPR001132, SM00524): MH2 domain |
97 |
SMAD5 | interactor | 5 | 1.000 | 0 | MH1 (PF03165, IPR003619, SM00523): MH1 domain MH2 (PF03166, IPR001132, SM00524): MH2 domain |
98 |
SNW1 | protein found in more fusions | 33 | 0.198 | 258.737 | SKIP_SNW (PF02731, IPR004015): SKIP/SNW domain PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term SIR4_SID (PF16991, IPR031556): Sir4 SID domain |
99 |
SPI1 | suppressor | 9 | 0.556 | 8.533 | Ets (PF00178, IPR000418, SM00413): Ets-domain p47_phox_C (PF08944, IPR015039): NADPH oxidase subunit p47Phox, C terminal domain |
100 |
SQRDL | interactor | 3 | 1.000 | 0 | Pyr_redox_2 (PF07992, IPR023753): Pyridine nucleotide-disulphide oxidoreductase |
101 |
SQSTM1 | oncoprotein | 12 | 0.382 | 22.133 | PB1 (PF00564, IPR000270, SM00666): PB1 domain ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type UBA_5 (PF16577, IPR015940): UBA domain |
102 |
STK38 | interactor | 4 | 1.000 | 0 | MEKHLA (PF08670, IPR013978): MEKHLA domain Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain |
103 |
STK38L | oncoprotein | 3 | 1.000 | 0 | Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain |
104 |
TBL1XR1 | oncoprotein | 6 | 0.800 | 0.915 | LisH (PF08513, IPR013720, SM00667): LisH WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat |
105 |
TCP1 | interactor | 11 | 0.491 | 12.438 | Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family |
106 |
TEAD1 | interactor | 2 | 1.000 | 0 | TEA (PF01285, IPR000818, SM00426): TEA/ATTS domain family |
107 |
TEAD4 | interactor | 3 | 0.667 | 1.000 | TEA (PF01285, IPR000818, SM00426): TEA/ATTS domain family |
108 |
TGFBR1 | oncoprotein | 6 | 0.867 | 0.733 | Activin_recp (PF01064, IPR000472): Activin types I and II receptor domain Pkinase (PF00069, IPR000719): Protein kinase domain TGF_beta_GS (PF08515, IPR003605, SM00467): Transforming growth factor beta type I GS-motif |
109 |
TP53 | suppressor | 56 | 0.186 | 853.716 | DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region P53 (PF00870, IPR011615): P53 DNA-binding domain P53_tetramer (PF07710, IPR010991): P53 tetramerisation motif |
110 |
TRIM28 | protein found in more fusions | 10 | 0.611 | 5.606 | ASFV_J13L (PF05568, IPR008385): African swine fever virus J13L protein K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain PHD (PF00628, IPR019787, SM00249): PHD-finger FYVE_2 (PF02318, IPR010911): FYVE-type zinc finger zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger zf-RING_5 (PF14634, IPR001841): zinc-RING finger domain SKA2 (PF16740, IPR026762): Spindle and kinetochore-associated protein 2 |
111 |
TUBA1A | oncoprotein | 13 | 0.462 | 24.162 | Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain |
112 |
TUBA1B | interactor | 9 | 0.417 | 11.352 | Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain |
113 |
TUBA4A | interactor | 9 | 0.611 | 6.994 | Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain |
114 |
TUBB | interactor | 12 | 0.576 | 11.889 | Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain |
115 |
TUBB2A | interactor | 9 | 0.500 | 10.550 | Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain |
116 |
TUBB6 | interactor | 7 | 0.429 | 8.833 | Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain |
117 |
TUFM | interactor | 8 | 0.464 | 10.367 | GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2 GTP_EFTU_D3 (PF03143, IPR004160): Elongation factor Tu C-terminal domain |
118 |
UBE2I | interactor | 21 | 0.374 | 59.038 | UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme |
119 |
UQCRC2 | oncoprotein | 14 | 0.275 | 46.733 | Peptidase_M16 (PF00675, IPR011765): Insulinase (Peptidase family M16) Peptidase_M16_C (PF05193, IPR007863): Peptidase M16 inactive domain |
120 |
WDR26 | interactor | 2 | 1.000 | 0 | eIF2A (PF08662, IPR013979): Eukaryotic translation initiation factor eIF2A WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 |