1 |
SH3GL2 | parental protein | 58 | 0.055 | 2668.467 | BAR (PF03114, IPR004148, SM00721): BAR domain SH3_2 (PF07653, IPR011511): Variant SH3 domain |
2 |
ACTG1 | protein found in more fusions | 3 | 1.000 | 0 | Actin (PF00022, IPR004000, SM00268): Actin |
3 |
ADAM15 | interactor | 1 | 0 | 0 | CD20 (PF04103, IPR007237): CD20-like family Pep_M12B_propep (PF01562, IPR002870): Reprolysin family propeptide Reprolysin (PF01421, IPR001590): Reprolysin (M12B) family zinc metalloprotease ADAM_CR (PF08516, IPR006586, SM00608): ADAM cysteine-rich Disintegrin (PF00200, IPR001762, SM00050): Disintegrin |
4 |
ADAM19 | interactor | 1 | 0 | 0 | Adeno_E3_CR2 (PF02439, IPR003470): Adenovirus E3 region protein CR2 EGF_2 (PF07974, IPR013111): EGF-like domain Pep_M12B_propep (PF01562, IPR002870): Reprolysin family propeptide Reprolysin (PF01421, IPR001590): Reprolysin (M12B) family zinc metalloprotease ADAM_CR (PF08516, IPR006586, SM00608): ADAM cysteine-rich Disintegrin (PF00200, IPR001762, SM00050): Disintegrin |
5 |
ADAM9 | oncoprotein | 1 | 0 | 0 | EB (PF01683, IPR006149): EB module Pep_M12B_propep (PF01562, IPR002870): Reprolysin family propeptide Reprolysin (PF01421, IPR001590): Reprolysin (M12B) family zinc metalloprotease ADAM_CR (PF08516, IPR006586, SM00608): ADAM cysteine-rich Disintegrin (PF00200, IPR001762, SM00050): Disintegrin |
6 |
AMPH | oncoprotein | 8 | 0.429 | 13.733 | BAR (PF03114, IPR004148, SM00721): BAR domain SH3_9 (PF14604, IPR001452): Variant SH3 domain PBP_N (PF17093, IPR031375): Penicillin-binding protein N-terminus |
7 |
APP | protein found in more fusions | 15 | 0.176 | 73.833 | APP_N (PF02177, IPR015849, SM00006): Amyloid A4 N-terminal heparin-binding Beta-APP (PF03494, IPR013803): Beta-amyloid peptide (beta-APP) BUD22 (PF09073, IPR015158): BUD22 IncA (PF04156, IPR007285): IncA protein Kunitz_BPTI (PF00014, IPR002223, SM00131): Kunitz/Bovine pancreatic trypsin inhibitor domain APP_amyloid (PF10515, IPR019543): beta-amyloid precursor protein C-terminus APP_Cu_bd (PF12924, IPR011178): Copper-binding of amyloid precursor, CuBD APP_E2 (PF12925, IPR024329): E2 domain of amyloid precursor protein |
8 |
ARHGAP8 | interactor | 3 | 1.000 | 0 | RhoGAP (PF00620, IPR000198, SM00324): RhoGAP domain CRAL_TRIO (PF00650, IPR001251, SM00516): CRAL/TRIO domain CRAL_TRIO_2 (PF13716, IPR001251): Divergent CRAL/TRIO domain |
9 |
ARNT2 | interactor | 2 | 1.000 | 0 | HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain PAS (PF00989, IPR013767, SM00091): PAS fold PAS_3 (PF08447, IPR013655): PAS fold PAP2 (PF01569, IPR000326, SM00014): PAP2 superfamily |
10 |
ATXN2 | interactor | 4 | 1.000 | 0 | LsmAD (PF06741, IPR009604): LsmAD domain PAM2 (PF07145, IPR009818): Ataxin-2 C-terminal region DUF3446 (PF11928, IPR021849): Domain of unknown function (DUF3446) Spt20 (PF12090, IPR021950): Spt20 family SM-ATX (PF14438, IPR025852): Ataxin 2 SM domain |
11 |
AZU1 | interactor | 2 | 1.000 | 0 | Trypsin (PF00089, IPR001254, SM00020): Trypsin |
12 |
CBL | suppressor | 10 | 0.472 | 13.633 | Cbl_N (PF02262, IPR003153): CBL proto-oncogene N-terminal domain 1 Cbl_N2 (PF02761, IPR014741): CBL proto-oncogene N-terminus, EF hand-like domain Cbl_N3 (PF02762, IPR014742): CBL proto-oncogene N-terminus, SH2-like domain UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain Prok-RING_4 (PF14447): Prokaryotic RING finger family 4 zf-RING_4 (PF14570): RING/Ubox like zinc-binding domain |
13 |
CD2AP | protein found in more fusions | 7 | 0.800 | 1.133 | SH3_1 (PF00018, IPR001452, SM00326): SH3 domain SH3_9 (PF14604, IPR001452): Variant SH3 domain betaPIX_CC (PF16523, IPR032409): betaPIX coiled coil |
14 |
CLEC3B | interactor | 2 | 1.000 | 0 | Chordopox_A33R (PF05966, IPR009238): Chordopoxvirus A33R protein Ribosomal_L29 (PF00831, IPR001854): Ribosomal L29 protein Lectin_C (PF00059, IPR001304, SM00034): Lectin C-type domain |
15 |
DACT1 | suppressor | 1 | 0 | 0 | Dapper (PF15268, IPR024843): Dapper |
16 |
DLGAP4 | interactor | 1 | 0 | 0 | GKAP (PF03359, IPR005026): Guanylate-kinase-associated protein (GKAP) protein |
17 |
DNM1 | interactor | 9 | 0.500 | 9.633 | Dynamin_M (PF01031, IPR000375): Dynamin central region GED (PF02212, IPR003130, SM00302): Dynamin GTPase effector domain PH (PF00169, IPR001849, SM00233): PH domain Dynamin_N (PF00350, IPR001401, SM00053): Dynamin family |
18 |
DNM2 | interactor | 10 | 0.422 | 20.633 | Dynamin_M (PF01031, IPR000375): Dynamin central region GED (PF02212, IPR003130, SM00302): Dynamin GTPase effector domain PH (PF00169, IPR001849, SM00233): PH domain Dynamin_N (PF00350, IPR001401, SM00053): Dynamin family |
19 |
DNM3 | interactor | 4 | 0.667 | 1.000 | Dynamin_M (PF01031, IPR000375): Dynamin central region GED (PF02212, IPR003130, SM00302): Dynamin GTPase effector domain PH (PF00169, IPR001849, SM00233): PH domain Dynamin_N (PF00350, IPR001401, SM00053): Dynamin family |
20 |
DPPA4 | interactor | 5 | 0.833 | 0.667 | Ribosomal_L40e (PF01020, IPR001975): Ribosomal L40e family DCR (PF14047, IPR025891): Dppa2/4 conserved region Dppa2_A (PF14049, IPR025892): Dppa2/4 conserved region in higher vertebrates |
21 |
DPYSL4 | interactor | 3 | 1.000 | 0 | Amidohydro_1 (PF01979, IPR006680): Amidohydrolase family Amidohydro_3 (PF07969, IPR013108): Amidohydrolase family |
22 |
DYRK1A | oncoprotein | 5 | 0.667 | 1.333 | DUF755 (PF05501, IPR008474): Domain of unknown function (DUF755) Filament_head (PF04732, IPR006821): Intermediate filament head (DNA binding) region Pkinase (PF00069, IPR000719): Protein kinase domain FAM199X (PF15814, IPR029672): Protein family FAM199X |
23 |
EGFL6 | oncoprotein | 2 | 1.000 | 0 | C_tripleX (PF02363, IPR003341): Cysteine rich repeat EGF_2 (PF07974, IPR013111): EGF-like domain EGF_CA (PF07645, IPR001881, SM00179): Calcium-binding EGF domain MAM (PF00629, IPR000998, SM00137): MAM domain, meprin/A5/mu hEGF (PF12661, IPR013032): Human growth factor-like EGF cEGF (PF12662, IPR026823): Complement Clr-like EGF-like FXa_inhibition (PF14670): Coagulation Factor Xa inhibitory site |
24 |
EGFR | oncoprotein | 16 | 0.305 | 60.700 | Furin-like (PF00757, IPR006211): Furin-like cysteine rich region Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase Recep_L_domain (PF01030, IPR000494): Receptor L domain GAPT (PF11770, IPR021082): GRB2-binding adapter (GAPT) GF_recep_IV (PF14843, IPR032778): Growth factor receptor domain IV |
25 |
EMD | interactor | 6 | 0.600 | 3.333 | LEM (PF03020, IPR003887, SM00540): LEM domain SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein |
26 |
ERH | interactor | 3 | 1.000 | 0 | ER (PF01133, IPR000781): Enhancer of rudimentary |
27 |
F13A1 | protein found in more fusions | 2 | 0 | 0 | Transglut_C (PF00927, IPR008958): Transglutaminase family, C-terminal ig like domain Transglut_N (PF00868, IPR001102): Transglutaminase family Transglut_core (PF01841, IPR002931, SM00460): Transglutaminase-like superfamily |
28 |
GCH1 | interactor | 2 | 0 | 0 | GTP_cyclohydroI (PF01227, IPR020602): GTP cyclohydrolase I |
29 |
GSTM3 | interactor | 2 | 0 | 0 | GST_C (PF00043, IPR004046): Glutathione S-transferase, C-terminal domain GST_N (PF02798, IPR004045): Glutathione S-transferase, N-terminal domain |
30 |
HLA-DQA1 | interactor | 1 | 0 | 0 | MHC_II_alpha (PF00993, IPR001003, SM00920): Class II histocompatibility antigen, alpha domain C1-set (PF07654, IPR003597, SM00407): Immunoglobulin C1-set domain C1-set_C (PF16196, IPR032431): C1-set C-terminal domain |
31 |
IGHM | interactor | 2 | 1.000 | 0 | C2-set_2 (PF08205, IPR013162): CD80-like C2-set immunoglobulin domain C1-set (PF07654, IPR003597, SM00407): Immunoglobulin C1-set domain |
32 |
IL6 | oncoprotein | 1 | 0 | 0 | IL6 (PF00489, IPR003573, SM00126): Interleukin-6/G-CSF/MGF family |
33 |
IPO11 | interactor | 2 | 1.000 | 0 | DUF1539 (PF07560, IPR011436): Domain of Unknown Function (DUF1539) HEAT (PF02985, IPR000357): HEAT repeat IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain Xpo1 (PF08389, IPR013598): Exportin 1-like protein HEAT_2 (PF13646): HEAT repeats |
34 |
ITCH | interactor | 7 | 0.600 | 3.333 | C2 (PF00168, IPR000008, SM00239): C2 domain WW (PF00397, IPR001202, SM00456): WW domain HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase) |
35 |
ITSN1 | interactor | 10 | 0.528 | 10.500 | C2 (PF00168, IPR000008, SM00239): C2 domain VIT1 (PF01988, IPR008217): VIT family DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664) FmdE (PF02663, IPR003814): FmdE, Molybdenum formylmethanofuran dehydrogenase operon GSH_synthase (PF03199, IPR004887): Eukaryotic glutathione synthase RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain EF-hand_4 (PF12763, IPR000261): Cytoskeletal-regulatory complex EF hand DUF3915 (PF13054, IPR025026): Protein of unknown function (DUF3915) SH3_9 (PF14604, IPR001452): Variant SH3 domain DUF4748 (PF15932, IPR031833): Domain of unknown function (DUF4748) INTAP (PF16617): Intersectin and clathrin adaptor AP2 binding region PH_13 (PF16652, IPR001849): Pleckstrin homology domain |
36 |
LCP2 | interactor | 4 | 0.833 | 0.667 | SAM_2 (PF07647, IPR011510): SAM domain (Sterile alpha motif) SDA1 (PF05285, IPR007949): SDA1 SH2 (PF00017, IPR000980, SM00252): SH2 domain |
37 |
LRRK2 | oncoprotein | 7 | 0.400 | 7.000 | Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat ATP-synt_ab (PF00006, IPR000194): ATP synthase alpha/beta family, nucleotide-binding domain DUF1043 (PF06295, IPR009386): Protein of unknown function (DUF1043) T2SSE (PF00437, IPR001482): Type II/IV secretion system protein Roc (PF08477, IPR013684): Ras of Complex, Roc, domain of DAPkinase Pkinase (PF00069, IPR000719): Protein kinase domain Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies) PQQ_2 (PF13360, IPR002372): PQQ-like domain LRR_8 (PF13855, IPR001611): Leucine rich repeat COR (PF16095, IPR032171): C-terminal of Roc, COR, domain |
38 |
MAST2 | oncoprotein | 2 | 1.000 | 0 | DUF1908 (PF08926, IPR015022): Domain of unknown function (DUF1908) PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) Pkinase (PF00069, IPR000719): Protein kinase domain |
39 |
PAXIP1 | interactor | 4 | 0.667 | 1.667 | BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain IPT (PF01745, IPR002648, SM00429): Isopentenyl transferase SURF6 (PF04935, IPR007019): Surfeit locus protein 6 DUF2052 (PF09747, IPR018613): Coiled-coil domain containing protein (DUF2052) CYSTM (PF12734, IPR028144): Cysteine-rich TM module stress tolerance PTCB-BRCT (PF12738, IPR001357): twin BRCT domain BRCT_2 (PF16589, IPR001357): BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT (PF16759, IPR031916): DNA ligase 3 BRCT domain RTT107_BRCT_5 (PF16770, IPR001357): Regulator of Ty1 transposition protein 107 BRCT domain |
40 |
PDCD6IP | interactor | 9 | 0.500 | 8.367 | BRO1 (PF03097, IPR004328, SM01041): BRO1-like domain MSA-2c (PF12238, IPR021060): Merozoite surface antigen 2c ALIX_LYPXL_bnd (PF13949, IPR025304): ALIX V-shaped domain binding to HIV |
41 |
PPP1R21 | interactor | 1 | 0 | 0 | TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein KLRAQ (PF10205, IPR019343): Predicted coiled-coil domain-containing protein TTKRSYEDQ (PF10212, IPR019348): Predicted coiled-coil domain-containing protein |
42 |
PPP6R1 | interactor | 2 | 1.000 | 0 | CENP-B_dimeris (PF09026, IPR015115): Centromere protein B dimerisation domain SAPS (PF04499, IPR007587): SIT4 phosphatase-associated protein WRNPLPNID (PF15017): Putative WW-binding domain and destruction box |
43 |
PRR14 | interactor | 2 | 1.000 | 0 | CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal Tantalus (PF15386, IPR028149): Drosophila Tantalus-like |
44 |
PTPN23 | suppressor | 4 | 0.667 | 1.000 | BRO1 (PF03097, IPR004328, SM01041): BRO1-like domain Y_phosphatase (PF00102, IPR000242, SM00194): Protein-tyrosine phosphatase SOGA (PF11365, IPR027881): Protein SOGA ALIX_LYPXL_bnd (PF13949, IPR025304): ALIX V-shaped domain binding to HIV |
45 |
SH3GL1 | oncoprotein | 11 | 0.289 | 26.567 | BAR (PF03114, IPR004148, SM00721): BAR domain PhnG (PF06754, IPR009609): Phosphonate metabolism protein PhnG SH3_1 (PF00018, IPR001452, SM00326): SH3 domain |
46 |
SH3GL3 | interactor | 15 | 0.264 | 59.900 | BAR (PF03114, IPR004148, SM00721): BAR domain SH3_2 (PF07653, IPR011511): Variant SH3 domain |
47 |
SH3KBP1 | protein found in more fusions | 13 | 0.424 | 27.267 | Tmemb_cc2 (PF10267, IPR019394): Predicted transmembrane and coiled-coil 2 protein SH3_9 (PF14604, IPR001452): Variant SH3 domain |
48 |
SYNJ1 | interactor | 5 | 0.600 | 1.967 | DUF1866 (PF08952, IPR015047, SM01165): Domain of unknown function (DUF1866) Exo_endo_phos (PF03372, IPR005135): Endonuclease/Exonuclease/phosphatase family Syja_N (PF02383, IPR002013): SacI homology domain YppG (PF14179, IPR025555): YppG-like protein |
49 |
SYNM | suppressor | 3 | 0.667 | 0.667 | Filament (PF00038, IPR001664): Intermediate filament protein CCDC-167 (PF15188, IPR028194): Coiled-coil domain-containing protein 167 |
50 |
TANGO2 | interactor | 1 | 0 | 0 | TANGO2 (PF05742, IPR008551): Transport and Golgi organisation 2 |
51 |
TCEA2 | interactor | 2 | 1.000 | 0 | Med26 (PF08711, IPR017923): TFIIS helical bundle-like domain TFIIS_C (PF01096, IPR001222): Transcription factor S-II (TFIIS) TFIIS_M (PF07500, IPR003618): Transcription factor S-II (TFIIS), central domain DUF4423 (PF14394, IPR025537): Domain of unknown function (DUF4423) |
52 |
TERF1 | interactor | 4 | 0.667 | 1.000 | TRF (PF08558, IPR013867): Telomere repeat binding factor (TRF) Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain |
53 |
TIAM2 | interactor | 2 | 1.000 | 0 | PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) PH (PF00169, IPR001849, SM00233): PH domain RBD (PF02196, IPR003116, SM00455): Raf-like Ras-binding domain RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain CENP-F_leu_zip (PF10473, IPR019513): Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PH_6 (PF15406): Pleckstrin homology domain |
54 |
TMEM108 | interactor | 1 | 0 | 0 | TMEM108 (PF15759, IPR031508): TMEM108 family |
55 |
TYMS | interactor | 1 | 0 | 0 | Thymidylat_synt (PF00303, IPR000398): Thymidylate synthase |
56 |
ZNF219 | interactor | 2 | 1.000 | 0 | Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zinc_ribbon_10 (PF10058, IPR019273): Predicted integral membrane zinc-ribbon metal-binding protein DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360) zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_4 (PF13894): C2H2-type zinc finger zf-H2C2_5 (PF13909): C2H2-type zinc-finger domain PRIMA1 (PF16101): Proline-rich membrane anchor 1 |
57 |
ZNF580 | interactor | 1 | 0 | 0 | zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_4 (PF13894): C2H2-type zinc finger |
58 |
ZXDC | interactor | 2 | 1.000 | 0 | zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_4 (PF13894): C2H2-type zinc finger zf-C2H2_8 (PF15909, IPR031799): C2H2-type zinc ribbon |