1 |
SFPQ | parental protein | 162 | 0.140 | 10233.904 | GRP (PF07172, IPR010800): Glycine rich protein family Herpes_PAP (PF03325, IPR004997): Herpesvirus polymerase accessory protein NOPS (PF08075, IPR012975): NOPS (NUC059) domain RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit PAT1 (PF09770, IPR019167): Topoisomerase II-associated protein PAT1 CYSTM (PF12734, IPR028144): Cysteine-rich TM module stress tolerance |
2 |
ACAT1 | interactor | 14 | 0.410 | 17.291 | Thiolase_C (PF02803, IPR020617): Thiolase, C-terminal domain Thiolase_N (PF00108, IPR020616): Thiolase, N-terminal domain |
3 |
AHSA1 | interactor | 11 | 0.509 | 7.275 | Aha1_N (PF09229, IPR015310, SM01000): Activator of Hsp90 ATPase, N-terminal AHSA1 (PF08327, IPR013538): Activator of Hsp90 ATPase homolog 1-like protein |
4 |
AP2M1 | protein found in more fusions | 12 | 0.509 | 5.727 | Adap_comp_sub (PF00928, IPR008968): Adaptor complexes medium subunit family Clat_adaptor_s (PF01217, IPR022775): Clathrin adaptor complex small chain |
5 |
APBB1 | interactor | 15 | 0.396 | 13.526 | PID (PF00640, IPR006020, SM00462): Phosphotyrosine interaction domain (PTB/PID) WW (PF00397, IPR001202, SM00456): WW domain RNA_pol_3_Rpc31 (PF11705, IPR024661): DNA-directed RNA polymerase III subunit Rpc31 PID_2 (PF14719, IPR006020): Phosphotyrosine interaction domain (PTB/PID) |
6 |
APEX1 | interactor | 12 | 0.409 | 9.076 | Exo_endo_phos (PF03372, IPR005135): Endonuclease/Exonuclease/phosphatase family |
7 |
AR | oncoprotein | 20 | 0.339 | 49.040 | Androgen_recep (PF02166, IPR001103): Androgen receptor zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor |
8 |
ARRB2 | interactor | 27 | 0.368 | 50.721 | Arrestin_C (PF02752, IPR011022, SM01017): Arrestin (or S-antigen), C-terminal domain Arrestin_N (PF00339, IPR011021): Arrestin (or S-antigen), N-terminal domain |
9 |
ASB12 | interactor | 1 | 0 | 0 | Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_3 (PF13606, IPR002110): Ankyrin repeat SOCS_box (PF07525, IPR001496): SOCS box |
10 |
ASB18 | interactor | 3 | 0.667 | 0.133 | Ank (PF00023, IPR002110, SM00248): Ankyrin repeat Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_4 (PF13637): Ankyrin repeats (many copies) Ank_5 (PF13857): Ankyrin repeats (many copies) SOCS_box (PF07525, IPR001496): SOCS box |
11 |
ASB3 | interactor | 4 | 0.667 | 0.333 | Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_4 (PF13637): Ankyrin repeats (many copies) SOCS_box (PF07525, IPR001496): SOCS box |
12 |
BTK | suppressor | 4 | 0.667 | 0.500 | BTK (PF00779, IPR001562, SM00107): BTK motif PH (PF00169, IPR001849, SM00233): PH domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain |
13 |
CARS | oncoprotein | 3 | 1.000 | 0 | tRNA-synt_1e (PF01406, IPR024909): tRNA synthetases class I (C) catalytic domain |
14 |
CBLL1 | oncoprotein | 2 | 1.000 | 0 | Pex14_N (PF04695, IPR006785): Peroxisomal membrane anchor protein (Pex14p) conserved region zf-C2H2_4 (PF13894): C2H2-type zinc finger zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger) |
15 |
CCDC8 | interactor | 31 | 0.423 | 49.580 | Borrelia_P83 (PF05262, IPR007926): Borrelia P83/100 protein SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal PNMA (PF14893, IPR026523): PNMA |
16 |
CD81 | interactor | 17 | 0.450 | 12.161 | Tetraspannin (PF00335, IPR018499): Tetraspanin family |
17 |
CDC5L | interactor | 64 | 0.354 | 358.042 | OmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like) Pox_A_type_inc (PF04508, IPR007596): Viral A-type inclusion protein repeat Cir_N (PF10197, IPR019339, SM01083): N-terminal domain of CBF1 interacting co-repressor CIR Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain Myb_Cef (PF11831, IPR021786): pre-mRNA splicing factor component Myb_DNA-bind_6 (PF13921): Myb-like DNA-binding domain |
18 |
CDK2 | suppressor | 36 | 0.345 | 130.818 | Kdo (PF06293, IPR010440): Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase (PF00069, IPR000719): Protein kinase domain |
19 |
CEBPA | suppressor | 12 | 0.509 | 7.405 | Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator DUF2514 (PF10721, IPR019659): Protein of unknown function (DUF2514) bZIP_2 (PF07716, IPR004827, SM00338): Basic region leucine zipper |
20 |
COPS5 | protein found in more fusions | 48 | 0.342 | 229.495 | JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease |
21 |
COX5A | interactor | 5 | 0.500 | 2.778 | COX5A (PF02284, IPR003204): Cytochrome c oxidase subunit Va |
22 |
CRY1 | interactor | 13 | 0.288 | 12.348 | DNA_photolyase (PF00875, IPR006050): DNA photolyase FAD_binding_7 (PF03441, IPR005101): FAD binding domain of DNA photolyase |
23 |
CSNK2A1 | oncoprotein | 37 | 0.375 | 96.808 | Pkinase (PF00069, IPR000719): Protein kinase domain |
24 |
CUL7 | protein found in more fusions | 60 | 0.319 | 308.267 | ANAPC10 (PF03256, IPR004939): Anaphase-promoting complex, subunit 10 (APC10) Cullin (PF00888, IPR001373, SM00182): Cullin family DUF1918 (PF08940, IPR015035): Domain of unknown function (DUF1918) Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain Cul7 (PF11515, IPR021097): Mouse development and cellular proliferation protein Cullin-7 |
25 |
DDX17 | protein found in more fusions | 49 | 0.360 | 164.116 | CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal DEAD (PF00270, IPR011545): DEAD/DEAH box helicase Ferritin (PF00210, IPR008331): Ferritin-like domain GRP (PF07172, IPR010800): Glycine rich protein family Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain |
26 |
DDX21 | interactor | 34 | 0.408 | 55.893 | CRT10 (PF08728, IPR014839): CRT10 DEAD (PF00270, IPR011545): DEAD/DEAH box helicase GUCT (PF08152, IPR012562): GUCT (NUC152) domain Sulfatase (PF00884, IPR000917): Sulfatase MIP-T3 (PF10243): Microtubule-binding protein MIP-T3 Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain CPSF100_C (PF13299, IPR025069): Cleavage and polyadenylation factor 2 C-terminal |
27 |
DNAJC19 | interactor | 2 | 1.000 | 0 | DnaJ (PF00226, IPR001623, SM00271): DnaJ domain |
28 |
DPH5 | interactor | 4 | 0.500 | 0.408 | TP_methylase (PF00590, IPR000878): Tetrapyrrole (Corrin/Porphyrin) Methylases |
29 |
EED | suppressor | 52 | 0.297 | 270.467 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160 ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain |
30 |
EFTUD2 | interactor | 41 | 0.409 | 97.438 | EFG_C (PF00679, IPR000640, SM00838): Elongation factor G C-terminus EFG_IV (PF03764, IPR005517, SM00889): Elongation factor G, domain IV GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2 EFG_II (PF14492, IPR009022): Elongation Factor G, domain II EFTUD2 (PF16004, IPR031950): 116 kDa U5 small nuclear ribonucleoprotein component N-terminus |
31 |
EGFR | oncoprotein | 31 | 0.216 | 161.185 | Furin-like (PF00757, IPR006211): Furin-like cysteine rich region Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase Recep_L_domain (PF01030, IPR000494): Receptor L domain GAPT (PF11770, IPR021082): GRB2-binding adapter (GAPT) GF_recep_IV (PF14843, IPR032778): Growth factor receptor domain IV |
32 |
ELAVL1 | oncoprotein | 48 | 0.317 | 293.688 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
33 |
ERG | oncoprotein | 17 | 0.456 | 12.157 | Ets (PF00178, IPR000418, SM00413): Ets-domain SAM_2 (PF07647, IPR011510): SAM domain (Sterile alpha motif) SAM_PNT (PF02198, IPR003118, SM00251): Sterile alpha motif (SAM)/Pointed domain |
34 |
ESR1 | suppressor | 53 | 0.249 | 405.188 | Oest_recep (PF02159, IPR001292): Oestrogen receptor zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor ESR1_C (PF12743, IPR024736): Oestrogen-type nuclear receptor final C-terminal |
35 |
EXOSC5 | interactor | 2 | 1.000 | 0 | RNase_PH (PF01138, IPR001247): 3' exoribonuclease family, domain 1 RNase_PH_C (PF03725, IPR015847): 3' exoribonuclease family, domain 2 |
36 |
FHL2 | oncoprotein | 9 | 0.536 | 4.769 | LIM (PF00412, IPR001781, SM00132): LIM domain zf-ribbon_3 (PF13248): zinc-ribbon domain |
37 |
FN1 | oncoprotein | 42 | 0.330 | 132.891 | fn1 (PF00039, IPR000083, SM00058): Fibronectin type I domain fn2 (PF00040, IPR000562, SM00059): Fibronectin type II domain fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369) |
38 |
FUS | suppressor | 41 | 0.405 | 123.108 | Herpes_PAP (PF03325, IPR004997): Herpesvirus polymerase accessory protein RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SVS_QK (PF10578, IPR018942): Seminal vesicle protein repeat zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others Limkain-b1 (PF11608, IPR024582): Limkain b1 FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 Keratin_2_head (PF16208, IPR032444): Keratin type II head |
39 |
GAS7 | oncoprotein | 4 | 0.667 | 0.125 | DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664) FCH (PF00611, IPR001060, SM00055): Fes/CIP4, and EFC/F-BAR homology domain Lectin_N (PF03954, IPR005640): Hepatic lectin, N-terminal domain WW (PF00397, IPR001202, SM00456): WW domain YscO (PF07321, IPR009929): Type III secretion protein YscO SH3_9 (PF14604, IPR001452): Variant SH3 domain WW_FCH_linker (PF16623): Unstructured linker region between on GAS7 protein |
40 |
HDAC1 | suppressor | 36 | 0.286 | 183.040 | FSAP_sig_propep (PF03032, IPR004275): Frog skin active peptide family signal and propeptide Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain |
41 |
HDAC2 | suppressor | 36 | 0.299 | 160.051 | Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain NARP1 (PF12569, IPR021183): NMDA receptor-regulated protein 1 |
42 |
HDAC5 | protein found in more fusions | 34 | 0.388 | 71.584 | Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain NOA36 (PF06524, IPR010531): NOA36 protein Activator_LAG-3 (PF11498, IPR021587): Transcriptional activator LAG-3 HDAC4_Gln (PF12203, IPR024643): Glutamine rich N terminal domain of histone deacetylase 4 |
43 |
HIST3H3 | interactor | 18 | 0.556 | 14.633 | Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4 |
44 |
HN1 | interactor | 2 | 1.000 | 0 | JUPITER (PF17054): Microtubule-Associated protein Jupiter |
45 |
HNRNPA1 | interactor | 63 | 0.356 | 357.235 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HnRNPA1 (PF11627, IPR021662): Nuclear factor hnRNPA1 |
46 |
HNRNPA2B1 | oncoprotein | 48 | 0.362 | 173.356 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
47 |
HNRNPA3 | oncoprotein | 41 | 0.432 | 94.059 | IATP (PF04568, IPR007648): Mitochondrial ATPase inhibitor, IATP RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 |
48 |
HNRNPC | protein found in more fusions | 46 | 0.383 | 144.106 | APG6 (PF04111, IPR007243): Autophagy protein Apg6 RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SURF2 (PF05477, IPR008833): Surfeit locus protein 2 (SURF2) |
49 |
HNRNPD | oncoprotein | 44 | 0.378 | 118.749 | CBFNT (PF08143, IPR012956): CBFNT (NUC161) domain NID (PF07292, IPR009909): Nmi/IFP 35 domain (NID) RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Keratin_2_head (PF16208, IPR032444): Keratin type II head |
50 |
HNRNPL | protein found in more fusions | 39 | 0.484 | 100.013 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Dscam_C (PF12355, IPR021012): Down syndrome cell adhesion molecule C terminal RRM_5 (PF13893): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
51 |
HNRNPM | interactor | 57 | 0.328 | 306.389 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HnRNP_M (PF11532, IPR024666): Heterogeneous nuclear ribonucleoprotein M Collagen_mid (PF15984, IPR031929): Bacterial collagen, middle region |
52 |
HNRNPR | interactor | 54 | 0.370 | 249.429 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 (PF11608, IPR024582): Limkain b1 |
53 |
HTATSF1 | interactor | 12 | 0.379 | 11.796 | BUD22 (PF09073, IPR015158): BUD22 Conotoxin (PF02950, IPR004214): Conotoxin Vfa1 (PF08432, IPR013640): AAA-ATPase Vps4-associated protein 1 PSK (PF06404, IPR009438): Phytosulfokine precursor protein (PSK) RNA_polI_A34 (PF08208, IPR013240): DNA-directed RNA polymerase I subunit RPA34.5 RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
54 |
HUWE1 | oncoprotein | 34 | 0.312 | 118.778 | BUD22 (PF09073, IPR015158): BUD22 DUF908 (PF06012, IPR010309): Domain of Unknown Function (DUF908) DUF913 (PF06025, IPR010314): Domain of Unknown Function (DUF913) FdhE (PF04216, IPR006452): Protein involved in formate dehydrogenase formation HABP4_PAI-RBP1 (PF04774, IPR006861): Hyaluronan / mRNA binding family Ku_C (PF03730, IPR005160): Ku70/Ku80 C-terminal arm Merozoite_SPAM (PF07133, IPR010784): Merozoite surface protein (SPAM) Mucin (PF01456, IPR000458): Mucin-like glycoprotein Nop14 (PF04147, IPR007276): Nop14-like family PBP_sp32 (PF07222, IPR009865): Proacrosin binding protein sp32 RNA_pol_Rpc4 (PF05132, IPR007811): RNA polymerase III RPC4 TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain WWE (PF02825, IPR004170, SM00678): WWE domain HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase) Tim54 (PF11711, IPR021056): Inner membrane protein import complex subunit Tim54 U1snRNP70_N (PF12220, IPR022023): U1 small nuclear ribonucleoprotein of 70kDa MW N terminal DUF4414 (PF14377, IPR025527): Domain of unknown function (DUF4414) |
55 |
ILF3 | oncoprotein | 44 | 0.356 | 138.630 | dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif DZF (PF07528, IPR006561, SM00572): DZF domain |
56 |
IMMT | protein found in more fusions | 17 | 0.350 | 28.469 | Mitofilin (PF09731, IPR019133): Mitochondrial inner membrane protein |
57 |
ITGA4 | interactor | 39 | 0.377 | 110.199 | FG-GAP (PF01839, IPR013517): FG-GAP repeat Integrin_alpha (PF00357, IPR018184): Integrin alpha cytoplasmic region Integrin_alpha2 (PF08441, IPR013649): Integrin alpha |
58 |
KHDRBS1 | protein found in more fusions | 28 | 0.342 | 104.527 | KH_1 (PF00013, IPR004088, SM00322): KH domain Qua1 (PF16274, IPR032571): Qua1 domain Sam68-YY (PF16568, IPR032335): Tyrosine-rich domain of Sam68 |
59 |
KRAS | oncoprotein | 15 | 0.396 | 15.732 | Ras (PF00071, IPR001806, SM00173): Ras family |
60 |
LMO7 | oncoprotein | 12 | 0.530 | 9.886 | CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain DUF1764 (PF08576, IPR013885): Eukaryotic protein of unknown function (DUF1764) LIM (PF00412, IPR001781, SM00132): LIM domain PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) DUF2072 (PF09845, IPR018645): Zn-ribbon containing protein AAA_23 (PF13476): AAA domain DUF4757 (PF15949, IPR031865): Domain of unknown function (DUF4757) |
61 |
MAPK1 | oncoprotein | 16 | 0.314 | 29.616 | Pkinase (PF00069, IPR000719): Protein kinase domain |
62 |
MCM2 | oncoprotein | 53 | 0.324 | 336.803 | AAA_3 (PF07726, IPR011703): ATPase family associated with various cellular activities (AAA) MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family MCM2_N (PF12619, IPR008045): Mini-chromosome maintenance protein 2 MCM_N (PF14551, IPR027925): MCM N-terminal domain MCM_OB (PF17207): MCM OB domain |
63 |
MCM5 | oncoprotein | 31 | 0.475 | 60.346 | MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family MCM_N (PF14551, IPR027925): MCM N-terminal domain MCM_OB (PF17207): MCM OB domain |
64 |
MDM2 | oncoprotein | 34 | 0.294 | 146.891 | Pinin_SDK_N (PF04697, IPR006787): pinin/SDK conserved region Presenilin (PF01080, IPR001108): Presenilin SWIB (PF02201, IPR003121, SM00151): SWIB/MDM2 domain zf-FPG_IleRS (PF06827, IPR010663): Zinc finger found in FPG and IleRS zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger) |
65 |
MOV10 | interactor | 25 | 0.347 | 62.666 | AAA_12 (PF13087): AAA domain AAA_30 (PF13604): AAA domain |
66 |
MUS81 | suppressor | 3 | 0.667 | 0.133 | ERCC4 (PF02732, IPR006166, SM00891): ERCC4 domain MutL (PF13941, IPR006230): MutL protein HHH_8 (PF14716, IPR010996): Helix-hairpin-helix domain |
67 |
NDUFS3 | protein found in more fusions | 18 | 0.390 | 23.451 | Complex1_30kDa (PF00329, IPR001268): Respiratory-chain NADH dehydrogenase, 30 Kd subunit |
68 |
NONO | oncoprotein | 68 | 0.221 | 779.624 | GvpL_GvpF (PF06386, IPR009430): Gas vesicle synthesis protein GvpL/GvpF NOPS (PF08075, IPR012975): NOPS (NUC059) domain RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PAS_7 (PF12860): PAS fold SUIM_assoc (PF16619): Unstructured region C-term to UIM in Ataxin3 |
69 |
NR2C1 | interactor | 7 | 0.905 | 0.333 | zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) DUF2318 (PF10080, IPR018758): Predicted membrane protein (DUF2318) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor |
70 |
NR3C1 | protein found in more fusions | 20 | 0.298 | 45.752 | GCR (PF02155, IPR001409): Glucocorticoid receptor zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor |
71 |
NR4A2 | oncoprotein | 6 | 0.533 | 2.444 | zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor |
72 |
NTRK1 | oncoprotein | 78 | 0.236 | 827.275 | I-set (PF07679, IPR013098): Immunoglobulin I-set domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase LRR_8 (PF13855, IPR001611): Leucine rich repeat TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain |
73 |
NUP210 | interactor | 11 | 0.400 | 11.417 | Big_2 (PF02368, IPR003343, SM00635): Bacterial Ig-like domain (group 2) |
74 |
NXF1 | interactor | 34 | 0.273 | 145.268 | NTF2 (PF02136, IPR002075): Nuclear transport factor 2 (NTF2) domain Tap-RNA_bind (PF09162, IPR015245): Tap, RNA-binding TAP_C (PF03943, IPR005637, SM00804): TAP C-terminal domain LRR_8 (PF13855, IPR001611): Leucine rich repeat |
75 |
OBSL1 | interactor | 55 | 0.347 | 225.295 | BiPBP_C (PF06832, IPR009647): Penicillin-Binding Protein C-terminus Family fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain Herpes_gE (PF02480, IPR003404): Alphaherpesvirus glycoprotein E I-set (PF07679, IPR013098): Immunoglobulin I-set domain V-set (PF07686, IPR013106): Immunoglobulin V-set domain Ig_3 (PF13927): Immunoglobulin domain Ig_4 (PF16680, IPR032052): T-cell surface glycoprotein CD3 delta chain Izumo-Ig (PF16706, IPR032699): Izumo-like Immunoglobulin domain |
76 |
ORC6 | interactor | 6 | 0.733 | 0.415 | ORC6 (PF05460, IPR008721): Origin recognition complex subunit 6 (ORC6) |
77 |
PAN2 | interactor | 22 | 0.394 | 27.080 | RNase_T (PF00929, IPR013520): Exonuclease UCH_1 (PF13423, IPR001394): Ubiquitin carboxyl-terminal hydrolase WD40_like (PF17005, IPR031544): WD40-like domain |
78 |
PARK2 | suppressor | 24 | 0.312 | 61.735 | IBR (PF01485, IPR002867, SM00647): IBR domain, a half RING-finger domain ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family |
79 |
PARK7 | suppressor | 15 | 0.341 | 27.206 | DJ-1_PfpI (PF01965, IPR002818): DJ-1/PfpI family |
80 |
PFKM | protein found in more fusions | 10 | 0.444 | 7.819 | PFK (PF00365, IPR000023): Phosphofructokinase |
81 |
PGK1 | interactor | 19 | 0.550 | 16.008 | PGK (PF00162, IPR001576): Phosphoglycerate kinase |
82 |
PHF5A | interactor | 6 | 0.733 | 0.352 | PHF5 (PF03660, IPR005345): PHF5-like protein |
83 |
PIN1 | suppressor | 17 | 0.441 | 23.840 | Rotamase (PF00639, IPR000297): PPIC-type PPIASE domain WW (PF00397, IPR001202, SM00456): WW domain |
84 |
PITX3 | interactor | 3 | 1.000 | 0 | OAR (PF03826, IPR003654): OAR domain Homeobox (PF00046, IPR001356, SM00389): Homeobox domain |
85 |
POT1 | interactor | 6 | 0.400 | 2.222 | POT1 (PF02765, IPR011564, SM00976): Telomeric single stranded DNA binding POT1/CDC13 tRNA_anti-codon (PF01336, IPR004365): OB-fold nucleic acid binding domain POT1PC (PF16686, IPR032042): ssDNA-binding domain of telomere protection protein |
86 |
PPARG | suppressor | 15 | 0.352 | 34.557 | zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor PPARgamma_N (PF12577, IPR022590): PPAR gamma N-terminal region |
87 |
PPARGC1A | interactor | 9 | 0.472 | 8.312 | Pap_E4 (PF02711, IPR003861): E4 protein RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RSRP (PF17069): Arginine/Serine-Rich protein 1 |
88 |
PPP1CA | suppressor | 27 | 0.345 | 56.309 | Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase STPPase_N (PF16891, IPR031675): Serine-threonine protein phosphatase N-terminal domain |
89 |
PRKCI | interactor | 2 | 1.000 | 0 | PB1 (PF00564, IPR000270, SM00666): PB1 domain Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain) |
90 |
PRPF40A | protein found in more fusions | 32 | 0.501 | 39.903 | FF (PF01846, IPR002713, SM00441): FF domain MCR_alpha (PF02249, IPR009047): Methyl-coenzyme M reductase alpha subunit, C-terminal domain Transformer (PF06495, IPR010519): Fruit fly transformer protein WW (PF00397, IPR001202, SM00456): WW domain YqzE (PF14038, IPR025622): YqzE-like protein SPT6_acidic (PF14632, IPR028083): Acidic N-terminal SPT6 SRRM_C (PF15230, IPR029360): Serine/arginine repetitive matrix protein C-terminus SOBP (PF15279, IPR026092): Sine oculis-binding protein IHABP4_N (PF16174, IPR032381): Intracellular hyaluronan-binding protein 4 N-terminal |
91 |
PTBP1 | oncoprotein | 42 | 0.428 | 107.870 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 (PF13893): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
92 |
RAC1 | oncoprotein | 9 | 0.500 | 1.801 | Ras (PF00071, IPR001806, SM00173): Ras family |
93 |
RAD21 | oncoprotein | 19 | 0.444 | 25.107 | Rad21_Rec8 (PF04824, IPR006909): Conserved region of Rad21 / Rec8 like protein Rad21_Rec8_N (PF04825, IPR006910): N terminus of Rad21 / Rec8 like protein FAM176 (PF14851): FAM176 family WRNPLPNID (PF15017): Putative WW-binding domain and destruction box |
94 |
RNF43 | oncoprotein | 3 | 1.000 | 0 | IBR (PF01485, IPR002867, SM00647): IBR domain, a half RING-finger domain zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain |
95 |
RPA1 | suppressor | 45 | 0.428 | 120.715 | Rep-A_N (PF04057, IPR007199): Replication factor-A protein 1, N-terminal domain Rep_fac-A_C (PF08646, IPR013955): Replication factor-A C terminal domain tRNA_anti-codon (PF01336, IPR004365): OB-fold nucleic acid binding domain REPA_OB_2 (PF16900, IPR031657): Replication protein A OB domain |
96 |
RPA2 | oncoprotein | 41 | 0.377 | 114.945 | RPA_C (PF08784, IPR014892): Replication protein A C terminal tRNA_anti-codon (PF01336, IPR004365): OB-fold nucleic acid binding domain RMI2 (PF16100, IPR032245): RecQ-mediated genome instability protein 2 |
97 |
RPA3 | interactor | 37 | 0.395 | 77.679 | Rep_fac-A_3 (PF08661, IPR013970): Replication factor A protein 3 |
98 |
RPS6KB2 | interactor | 12 | 0.394 | 14.873 | Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain |
99 |
SART1 | interactor | 34 | 0.455 | 96.560 | SART-1 (PF03343, IPR005011): SART-1 family Dsh_C (PF12316, IPR024580): Segment polarity protein dishevelled (Dsh) C terminal |
100 |
SCARNA22 | interactor | 21 | 0.505 | 11.486 | NA |
101 |
SERBP1 | protein found in more fusions | 20 | 0.333 | 28.653 | HABP4_PAI-RBP1 (PF04774, IPR006861): Hyaluronan / mRNA binding family FXMRP1_C_core (PF12235, IPR022034): Fragile X-related 1 protein core C terminal FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 IHABP4_N (PF16174, IPR032381): Intracellular hyaluronan-binding protein 4 N-terminal |
102 |
SF3A1 | interactor | 45 | 0.390 | 166.073 | TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit Surp (PF01805, IPR000061, SM00648): Surp module ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family PRP21_like_P (PF12230, IPR022030): Pre-mRNA splicing factor PRP21 like protein |
103 |
SF3B1 | oncoprotein | 50 | 0.372 | 190.813 | Dopey_N (PF04118, IPR007249): Dopey, N-terminal HEAT (PF02985, IPR000357): HEAT repeat SF3b1 (PF08920, IPR015016): Splicing factor 3B subunit 1 UNC45-central (PF11701, IPR024660): Myosin-binding striated muscle assembly central Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region HEAT_EZ (PF13513): HEAT-like repeat HEAT_2 (PF13646): HEAT repeats |
104 |
SF3B3 | interactor | 50 | 0.355 | 209.888 | CPSF_A (PF03178, IPR004871): CPSF A subunit region MMS1_N (PF10433): Mono-functional DNA-alkylating methyl methanesulfonate N-term |
105 |
SFN | suppressor | 19 | 0.386 | 25.744 | 14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein |
106 |
SIN3A | oncoprotein | 22 | 0.368 | 56.882 | Sin3_corepress (PF08295, IPR013194, SM00761): Sin3 family co-repressor PAH (PF02671, IPR003822, SM00309): Paired amphipathic helix repeat Sin3a_C (PF16879, IPR031693): C-terminal domain of Sin3a protein |
107 |
SIRT7 | interactor | 41 | 0.273 | 200.673 | DUF563 (PF04577, IPR007657): Protein of unknown function (DUF563) SIR2 (PF02146, IPR003000): Sir2 family |
108 |
SLTM | interactor | 6 | 0.400 | 5.554 | DUF1980 (PF09323, IPR015402): Domain of unknown function (DUF1980) Neur_chan_memb (PF02932, IPR006029): Neurotransmitter-gated ion-channel transmembrane region Podoplanin (PF05808, IPR008783): Podoplanin RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SAP (PF02037, IPR003034, SM00513): SAP domain PTPRCAP (PF15713, IPR016553): Protein tyrosine phosphatase receptor type C-associated |
109 |
SMAD5 | interactor | 8 | 0.679 | 1.607 | MH1 (PF03165, IPR003619, SM00523): MH1 domain MH2 (PF03166, IPR001132, SM00524): MH2 domain |
110 |
SMARCA2 | suppressor | 18 | 0.431 | 30.609 | DUF1168 (PF06658, IPR009548): Protein of unknown function (DUF1168) DUF1840 (PF08895, IPR014991): Domain of unknown function (DUF1840) HSA (PF07529, IPR014012, SM00573): HSA QLQ (PF08880, IPR014978, SM00951): QLQ SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain YL1 (PF05764, IPR008895): YL1 nuclear protein BRK (PF07533, IPR006576, SM00592): BRK domain DUF2052 (PF09747, IPR018613): Coiled-coil domain containing protein (DUF2052) EPL1 (PF10513, IPR019542): Enhancer of polycomb-like Bromodomain (PF00439, IPR001487, SM00297): Bromodomain Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain SnAC (PF14619, IPR029295): Snf2-ATP coupling, chromatin remodelling complex WRNPLPNID (PF15017): Putative WW-binding domain and destruction box |
111 |
SMARCA5 | interactor | 22 | 0.514 | 20.001 | HAND (PF09110, IPR015194): HAND SLIDE (PF09111, IPR015195): SLIDE SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain DUF4200 (PF13863, IPR025252): Domain of unknown function (DUF4200) DBINO (PF13892, IPR020838): DNA-binding domain RCDG1 (PF15725, IPR031457): Renal cancer differentiation gene 1 protein |
112 |
SMARCD1 | interactor | 10 | 0.600 | 3.381 | ATP-synt_G (PF04718, IPR006808): Mitochondrial ATP synthase g subunit DivIC (PF04977, IPR007060): Septum formation initiator SWIB (PF02201, IPR003121, SM00151): SWIB/MDM2 domain |
113 |
SMC3 | oncoprotein | 24 | 0.464 | 29.697 | SMC_N (PF02463, IPR003395): RecF/RecN/SMC N terminal domain |
114 |
SMN1 | interactor | 20 | 0.392 | 23.639 | SMN (PF06003, IPR010304): Survival motor neuron protein (SMN) |
115 |
SNRPA | interactor | 22 | 0.500 | 23.220 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
116 |
SNRPA1 | interactor | 33 | 0.436 | 75.849 | LRR_9 (PF14580): Leucine-rich repeat |
117 |
SNRPD2 | interactor | 28 | 0.405 | 48.853 | LSM (PF01423, IPR001163): LSM domain |
118 |
SNW1 | protein found in more fusions | 48 | 0.398 | 186.243 | SKIP_SNW (PF02731, IPR004015): SKIP/SNW domain PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term SIR4_SID (PF16991, IPR031556): Sir4 SID domain |
119 |
SON | interactor | 19 | 0.678 | 6.443 | Asp-B-Hydro_N (PF05279, IPR007943): Aspartyl beta-hydroxylase N-terminal region G-patch (PF01585, IPR000467, SM00443): G-patch domain tRNA_synt_1c_R2 (PF04557, IPR007638): Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 Eapp_C (PF10238, IPR019370): E2F-associated phosphoprotein DND1_DSRM (PF14709): double strand RNA binding domain from DEAD END PROTEIN 1 GREB1 (PF15782, IPR028422): Gene regulated by oestrogen in breast cancer RSRP (PF17069): Arginine/Serine-Rich protein 1 |
120 |
SP1 | protein found in more fusions | 14 | 0.436 | 19.836 | zf-Di19 (PF05605, IPR008598): Drought induced 19 protein (Di19), zinc-binding Herpes_capsid (PF06112, IPR009299): Gammaherpesvirus capsid protein zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type Miga (PF10265, IPR019392): Mitoguardin zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 |
121 |
SP3 | interactor | 5 | 1.000 | 0 | K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain |
122 |
SREK1 | protein found in more fusions | 21 | 0.421 | 27.988 | Ureide_permease (PF07168, IPR009834): Ureide permease RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RP-C_C (PF11800, IPR021760): Replication protein C C-terminal region PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term DUF3915 (PF13054, IPR025026): Protein of unknown function (DUF3915) BRD4_CDT (PF17105, IPR031354): C-terminal domain of bromodomain protein 4 |
123 |
SRRM1 | interactor | 33 | 0.420 | 74.375 | DUF1754 (PF08555, IPR013865): Eukaryotic family of unknown function (DUF1754) ETRAMP (PF09716, IPR006389): Malarial early transcribed membrane protein (ETRAMP) Hepatitis_core (PF00906, IPR002006): Hepatitis core antigen MAP65_ASE1 (PF03999, IPR007145): Microtubule associated protein (MAP65/ASE1 family) PWI (PF01480, IPR002483, SM00311): PWI domain Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein |
124 |
SRRM2 | interactor | 45 | 0.441 | 123.527 | cwf21 (PF08312, IPR013170, SM01115): cwf21 domain DUF1754 (PF08555, IPR013865): Eukaryotic family of unknown function (DUF1754) Pap_E4 (PF02711, IPR003861): E4 protein RR_TM4-6 (PF06459, IPR009460): Ryanodine Receptor TM 4-6 CTD (PF12815, IPR024945, SM01104): Spt5 C-terminal nonapeptide repeat binding Spt4 DUF4614 (PF15391, IPR027884): Domain of unknown function (DUF4614) |
125 |
SRSF3 | oncoprotein | 29 | 0.357 | 70.832 | DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777) RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
126 |
SRSF4 | interactor | 14 | 0.440 | 16.789 | Corona_nucleoca (PF00937, IPR001218): Coronavirus nucleocapsid protein RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term |
127 |
SRSF5 | interactor | 33 | 0.428 | 77.962 | DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777) RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term |
128 |
SRSF7 | interactor | 28 | 0.511 | 29.959 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TP2 (PF01254, IPR000678): Nuclear transition protein 2 zf-CCHC (PF00098, IPR001878): Zinc knuckle |
129 |
SSR4 | interactor | 9 | 0.500 | 8.348 | TRAP-delta (PF05404, IPR008855): Translocon-associated protein, delta subunit precursor (TRAP-delta) OppC_N (PF12911, IPR025966): N-terminal TM domain of oligopeptide transport permease C |
130 |
STAG2 | oncoprotein | 9 | 0.750 | 1.233 | AdoHcyase_NAD (PF00670, IPR015878, SM00997): S-adenosyl-L-homocysteine hydrolase, NAD binding domain STAG (PF08514, IPR013721): STAG domain Cnd3 (PF12719, IPR025977): Nuclear condensing complex subunits, C-term domain DUF4446 (PF14584, IPR027981): Protein of unknown function (DUF4446) |
131 |
STAT6 | oncoprotein | 2 | 1.000 | 0 | SH2 (PF00017, IPR000980, SM00252): SH2 domain STAT_alpha (PF01017, IPR013800): STAT protein, all-alpha domain STAT_bind (PF02864, IPR013801): STAT protein, DNA binding domain STAT_int (PF02865, IPR013799, SM00964): STAT protein, protein interaction domain STAT6_C (PF14596, IPR028187): STAT6 C-terminal |
132 |
STAU1 | protein found in more fusions | 30 | 0.466 | 39.171 | dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif Staufen_C (PF16482, IPR032478): Staufen C-terminal domain |
133 |
TADA2A | interactor | 17 | 0.449 | 18.291 | SWIRM (PF04433, IPR007526): SWIRM domain Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain |
134 |
TARS | interactor | 13 | 0.551 | 4.595 | HGTP_anticodon (PF03129, IPR004154): Anticodon binding domain TGS (PF02824, IPR004095): TGS domain tRNA-synt_2b (PF00587, IPR002314): tRNA synthetase class II core domain (G, H, P, S and T) tRNA_SAD (PF07973, IPR012947, SM00863): Threonyl and Alanyl tRNA synthetase second additional domain |
135 |
TCERG1 | interactor | 21 | 0.519 | 17.524 | FF (PF01846, IPR002713, SM00441): FF domain WW (PF00397, IPR001202, SM00456): WW domain Folliculin (PF11704, IPR021713): Vesicle coat protein involved in Golgi to plasma membrane transport DUF3807 (PF12720, IPR024526): Protein of unknown function (DUF3807) DUF3886 (PF13025, IPR024980): Protein of unknown function (DUF3886) Spore_coat_CotO (PF14153, IPR025439): Spore coat protein CotO FAM150 (PF15129, IPR029364): FAM150 family |
136 |
THRAP3 | oncoprotein | 25 | 0.310 | 83.363 | API5 (PF05918, IPR008383): Apoptosis inhibitory protein 5 (API5) FXMRP1_C_core (PF12235, IPR022034): Fragile X-related 1 protein core C terminal DUF4228 (PF14009, IPR025322): Domain of unknown function (DUF4228) THRAP3_BCLAF1 (PF15440, IPR029199): THRAP3/BCLAF1 family |
137 |
TIMM10 | interactor | 5 | 0.600 | 2.567 | zf-Tim10_DDP (PF02953, IPR004217): Tim10/DDP family zinc finger |
138 |
TIMM23B | interactor | 2 | 1.000 | 0 | Tim17 (PF02466, IPR003397): Tim17/Tim22/Tim23/Pmp24 family |
139 |
TIMM9 | interactor | 5 | 0.500 | 3.091 | zf-Tim10_DDP (PF02953, IPR004217): Tim10/DDP family zinc finger |
140 |
TOMM40 | interactor | 3 | 0.667 | 0.333 | Porin_3 (PF01459, IPR027246): Eukaryotic porin |
141 |
TOP1 | oncoprotein | 39 | 0.506 | 62.384 | DUF1764 (PF08576, IPR013885): Eukaryotic protein of unknown function (DUF1764) Topoisom_I (PF01028, IPR013500): Eukaryotic DNA topoisomerase I, catalytic core Topoisom_I_N (PF02919, IPR008336): Eukaryotic DNA topoisomerase I, DNA binding fragment MCM_bind (PF09739, IPR019140): Mini-chromosome maintenance replisome factor Sox_N (PF12444, IPR022151): Sox developmental protein N terminal Topo_C_assoc (PF14370, IPR025834): C-terminal topoisomerase domain DUF4614 (PF15391, IPR027884): Domain of unknown function (DUF4614) TonB_N (PF16031): TonB N-terminal region |
142 |
TOP2B | oncoprotein | 18 | 0.366 | 19.428 | CENP-B_dimeris (PF09026, IPR015115): Centromere protein B dimerisation domain DASH_Spc19 (PF08287, IPR013251): Spc19 DNA_gyraseB (PF00204, IPR013506): DNA gyrase B DTHCT (PF08070, IPR012542): DTHCT (NUC029) region HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim (PF01751, IPR006171, SM00493): Toprim domain Anophelin (PF10731, IPR018932): Thrombin inhibitor from mosquito DNA_topoisoIV (PF00521, IPR002205, SM00434): DNA gyrase/topoisomerase IV, subunit A PBP1_TM (PF14812, IPR032730): Transmembrane domain of transglycosylase PBP1 at N-terminal TOPRIM_C (PF16898, IPR031660): C-terminal associated domain of TOPRIM |
143 |
TOPORS | suppressor | 11 | 0.509 | 5.230 | Rad50_zn_hook (PF04423, IPR007517): Rad50 zinc hook motif Med19 (PF10278, IPR019403): Mediator of RNA pol II transcription subunit 19 PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger) |
144 |
TPR | oncoprotein | 23 | 0.474 | 24.447 | Baculo_PEP_C (PF04513, IPR007601): Baculovirus polyhedron envelope protein, PEP, C terminus ZapB (PF06005, IPR009252): Cell division protein ZapB Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family IncA (PF04156, IPR007285): IncA protein Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein Seryl_tRNA_N (PF02403, IPR015866): Seryl-tRNA synthetase N-terminal domain TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein Jnk-SapK_ap_N (PF09744, IPR019143): JNK_SAPK-associated protein-1 XhlA (PF10779, IPR019715): Haemolysin XhlA ADIP (PF11559, IPR021622): Afadin- and alpha -actinin-Binding Alanine_zipper (PF11839, IPR021793): Alanine-zipper, major outer membrane lipoprotein DUF3373 (PF11853, IPR021803): Protein of unknown function (DUF3373) DUF4107 (PF13389, IPR025180): Protein of unknown function (DUF4107) JIP_LZII (PF16471, IPR032486): JNK-interacting protein leucine zipper II CREPT (PF16566, IPR032337): Cell-cycle alteration and expression-elevated protein in tumour DUF5082 (PF16888, IPR031681): Domain of unknown function (DUF5082) |
145 |
TSG101 | suppressor | 11 | 0.511 | 5.511 | APG6 (PF04111, IPR007243): Autophagy protein Apg6 Laminin_II (PF06009, IPR010307): Laminin Domain II UEV (PF05743, IPR008883): UEV domain Vps23_core (PF09454, IPR017916): Vps23 core domain |
146 |
TXN | oncoprotein | 12 | 0.303 | 16.474 | Thioredoxin (PF00085, IPR013766): Thioredoxin |
147 |
U2AF1 | oncoprotein | 22 | 0.688 | 9.991 | DUF1509 (PF07420, IPR010883): Protein of unknown function (DUF1509) KMP11 (PF03037, IPR004132): Kinetoplastid membrane protein 11 RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH (PF00642, IPR000571): Zinc finger C-x8-C-x5-C-x3-H type (and similar) |
148 |
U2AF2 | protein found in more fusions | 55 | 0.414 | 194.643 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Transformer (PF06495, IPR010519): Fruit fly transformer protein |
149 |
UBC | protein found in more fusions | 41 | 0.374 | 157.664 | ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family |
150 |
UBE2I | interactor | 31 | 0.287 | 122.620 | UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme |
151 |
UNK | interactor | 17 | 0.243 | 50.572 | MbeD_MobD (PF04899, IPR006983): MbeD/MobD like NUDE_C (PF04880, IPR006964): NUDE protein, C-terminal conserved region zf-CCCH (PF00642, IPR000571): Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF3450 (PF11932, IPR016866): Protein of unknown function (DUF3450) zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger) zf-CCCH_2 (PF14608): RNA-binding, Nab2-type zinc finger Torus (PF16131, IPR032297): Torus domain |
152 |
UQCRC2 | oncoprotein | 12 | 0.439 | 9.210 | Peptidase_M16 (PF00675, IPR011765): Insulinase (Peptidase family M16) Peptidase_M16_C (PF05193, IPR007863): Peptidase M16 inactive domain |
153 |
UQCRFS1P1 | interactor | 3 | 0.667 | 0.400 | NA |
154 |
UTP14A | interactor | 14 | 0.626 | 3.944 | Utp14 (PF04615, IPR006709): Utp14 protein |
155 |
VCAM1 | interactor | 32 | 0.381 | 64.741 | C2-set (PF05790, IPR008424): Immunoglobulin C2-set domain I-set (PF07679, IPR013098): Immunoglobulin I-set domain ig (PF00047, IPR013151, SM00409): Immunoglobulin domain V-set (PF07686, IPR013106): Immunoglobulin V-set domain Ig_3 (PF13927): Immunoglobulin domain |
156 |
VTN | interactor | 14 | 0.747 | 2.549 | Hemopexin (PF00045, IPR018487, SM00120): Hemopexin Somatomedin_B (PF01033, IPR001212, SM00201): Somatomedin B domain |
157 |
WBP11 | interactor | 10 | 0.467 | 7.010 | BUD22 (PF09073, IPR015158): BUD22 Pex14_N (PF04695, IPR006785): Peroxisomal membrane anchor protein (Pex14p) conserved region SspB (PF04386, IPR007481): Stringent starvation protein B Wbp11 (PF09429, IPR019007): WW domain binding protein 11 ABC_trans_N (PF14510, IPR029481): ABC-transporter extracellular N-terminal |
158 |
WBP4 | interactor | 13 | 0.423 | 11.144 | CDC45 (PF02724, IPR003874): CDC45-like protein WW (PF00397, IPR001202, SM00456): WW domain zf-U1 (PF06220, IPR013085, SM00451): U1 zinc finger TMCO5 (PF14992, IPR026617): TMCO5 family |
159 |
WWOX | suppressor | 21 | 0.410 | 17.887 | adh_short (PF00106, IPR002198): short chain dehydrogenase WW (PF00397, IPR001202, SM00456): WW domain |
160 |
YTHDF2 | interactor | 13 | 0.513 | 12.286 | YTH (PF04146, IPR007275): YT521-B-like domain DUF4106 (PF13388, IPR025179): Protein of unknown function (DUF4106) |
161 |
ZC3HAV1 | interactor | 7 | 0.571 | 4.747 | PARP (PF00644, IPR012317): Poly(ADP-ribose) polymerase catalytic domain WWE (PF02825, IPR004170, SM00678): WWE domain |
162 |
ZMYM2 | oncoprotein | 8 | 0.571 | 2.077 | YHS (PF04945, IPR007029): YHS domain zf-FCS (PF06467, IPR010507): MYM-type Zinc finger with FCS sequence motif DUF3504 (PF12012, IPR021893): Domain of unknown function (DUF3504) SOBP (PF15279, IPR026092): Sine oculis-binding protein |