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Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)105
The number (and %) of the onco-proteins49 (46.67 %)
The number (and %) of the tumor suppressors5 (4.76 %)
Total number of binary PPIs (saturation %)530 (9.71 %)
The number (and %) of affected PPIs105 (19.81 %)
The number of possible different fusions21
PPI diameter2
PPI radius1
The average degree of PPI9.238
Assortativity coefficient-0.3176
The network average Clustering coefficient0.517
The number (and %) of a zero Clustering coefficients7 (6.67 %)
The number (and %) of a zero Betweenness Centrality22 (20.95 %)

ACTIVE INTERACTORS


List of the fusions

PPI for parental proteins: SET All fusions
Proteins found in more fusions UGP2 (see 1 fusions); TERF2IP (see 1 fusions); APP (see 4 fusions); TRIM28 (see 1 fusions); NR3C1 (see 8 fusions); HUWE1 (see 2 fusions); PLOD2 (see 1 fusions); RAC1 (see 1 fusions); KDM5C (see 1 fusions); NAP1L1 (see 3 fusions); FAF1 (see 2 fusions); PRKAR1A (see 2 fusions); GAPDH/CDKN1A (see 1 fusions); CDH1 (see 3 fusions); KMT2A (see 16 fusions); MCM2 (see 1 fusions); UBR5 (see 4 fusions); FOS (see 4 fusions); TP53 (see 3 fusions); THAP7 (see 1 fusions); GAPDH (see 2 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 SETparental protein1050.0717674.117NAP (PF00956, IPR002164): Nucleosome assembly protein (NAP)
Nop14 (PF04147, IPR007276): Nop14-like family
DUF2457 (PF10446, IPR018853): Protein of unknown function (DUF2457)
2 ANP32Aoncoprotein140.34143.863SDA1 (PF05285, IPR007949): SDA1
LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies)
LRR_9 (PF14580): Leucine-rich repeat
3 APBB1interactor31.0000PID (PF00640, IPR006020, SM00462): Phosphotyrosine interaction domain (PTB/PID)
WW (PF00397, IPR001202, SM00456): WW domain
RNA_pol_3_Rpc31 (PF11705, IPR024661): DNA-directed RNA polymerase III subunit Rpc31
PID_2 (PF14719, IPR006020): Phosphotyrosine interaction domain (PTB/PID)
4 APEX1interactor110.29125.089Exo_endo_phos (PF03372, IPR005135): Endonuclease/Exonuclease/phosphatase family
5 APPprotein found in more fusions190.170108.752APP_N (PF02177, IPR015849, SM00006): Amyloid A4 N-terminal heparin-binding
Beta-APP (PF03494, IPR013803): Beta-amyloid peptide (beta-APP)
BUD22 (PF09073, IPR015158): BUD22
IncA (PF04156, IPR007285): IncA protein
Kunitz_BPTI (PF00014, IPR002223, SM00131): Kunitz/Bovine pancreatic trypsin inhibitor domain
APP_amyloid (PF10515, IPR019543): beta-amyloid precursor protein C-terminus
APP_Cu_bd (PF12924, IPR011178): Copper-binding of amyloid precursor, CuBD
APP_E2 (PF12925, IPR024329): E2 domain of amyloid precursor protein
6 BANF1interactor40.6670.667BAF (PF02961, IPR004122, SM01023): Barrier to autointegration factor
7 C11orf58interactor40.5002.067DUF3408 (PF11888, IPR021823): Protein of unknown function (DUF3408)
SMAP (PF15477, IPR028124): Small acidic protein family
8 CALM1interactor90.27814.683EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
9 CCNB1oncoprotein90.4729.160Adeno_E1A (PF02703, IPR003853): Early E1A protein
Cyclin_C (PF02984, IPR004367): Cyclin, C-terminal domain
Cyclin_N (PF00134, IPR006671): Cyclin, N-terminal domain
10 CD81interactor70.5333.286Tetraspannin (PF00335, IPR018499): Tetraspanin family
11 CDH1oncoprotein31.0000Cadherin_C (PF01049, IPR000233): Cadherin cytoplasmic region
Cadherin_pro (PF08758, IPR014868, SM01055): Cadherin prodomain like
Cadherin (PF00028, IPR002126, SM00112): Cadherin domain
12 CDK2oncoprotein260.233153.619Kdo (PF06293, IPR010440): Lipopolysaccharide kinase (Kdo/WaaP) family
Pkinase (PF00069, IPR000719): Protein kinase domain
13 CDK5R1oncoprotein30.6670.286CDK5_activator (PF03261, IPR004944): Cyclin-dependent kinase 5 activator protein
14 CDKN1Aoncoprotein110.49117.690CDI (PF02234, IPR003175): Cyclin-dependent kinase inhibitor
15 CHAF1Ainteractor90.5007.771CAF-1_p150 (PF11600): Chromatin assembly factor 1 complex p150 subunit, N-terminal
CAF1A (PF12253, IPR022043): Chromatin assembly factor 1 subunit A
CAF1-p150_C2 (PF15539, IPR029105): CAF1 complex subunit p150, region binding to CAF1-p60 at C-term
CAF1-p150_N (PF15557, IPR029091): CAF1 complex subunit p150, region binding to PCNA
16 CHRM2interactor21.00007tm_1 (PF00001, IPR000276): 7 transmembrane receptor (rhodopsin family)
17 CHRM3interactor1007tm_1 (PF00001, IPR000276): 7 transmembrane receptor (rhodopsin family)
GWT1 (PF06423, IPR009447): GWT1
18 CTCFoncoprotein21.0000cwf18 (PF08315, IPR013169): cwf18 pre-mRNA splicing factor
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger
zf-H2C2_5 (PF13909): C2H2-type zinc-finger domain
PBP1_TM (PF14812, IPR032730): Transmembrane domain of transglycosylase PBP1 at N-terminal
19 DGKEoncoprotein21.0000C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain)
DAGK_acc (PF00609, IPR000756, SM00045): Diacylglycerol kinase accessory domain
DAGK_cat (PF00781, IPR001206, SM00046): Diacylglycerol kinase catalytic domain
20 ELAVL1oncoprotein250.185170.454RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
21 ELF4oncoprotein21.0000Ets (PF00178, IPR000418, SM00413): Ets-domain
Elf-1_N (PF12310, IPR022084): Transcription factor protein N terminal
22 ESR1oncoprotein200.25186.215Oest_recep (PF02159, IPR001292): Oestrogen receptor
zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains)
Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
ESR1_C (PF12743, IPR024736): Oestrogen-type nuclear receptor final C-terminal
23 FAF1protein found in more fusions120.67310.666UBX (PF00789, IPR001012, SM00166): UBX domain
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
AAA_11 (PF13086): AAA domain
UBA_4 (PF14555): UBA-like domain
24 FAM111Binteractor100ParB (PF08775, IPR014884, SM00470): ParB family
Trypsin_2 (PF13365): Trypsin-like peptidase domain
25 FARSBinteractor150.64813.210B3_4 (PF03483, IPR005146, SM00873): B3/4 domain
B5 (PF03484, IPR005147, SM00874): tRNA synthetase B5 domain
26 FN1oncoprotein190.26966.645fn1 (PF00039, IPR000083, SM00058): Fibronectin type I domain
fn2 (PF00040, IPR000562, SM00059): Fibronectin type II domain
fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369)
27 FOSoncoprotein50.5002.400bZIP_1 (PF00170, IPR004827): bZIP transcription factor
28 FTH1interactor70.4007.667Coat_F (PF07875, IPR012851): Coat F domain
Ferritin (PF00210, IPR008331): Ferritin-like domain
29 FTSJ3interactor40.5001.222DUF1764 (PF08576, IPR013885): Eukaryotic protein of unknown function (DUF1764)
FtsJ (PF01728, IPR002877): FtsJ-like methyltransferase
M16C_assoc (PF08367, IPR013578): Peptidase M16C associated
Orthopox_F8 (PF05886, IPR008726): Orthopoxvirus F8 protein
Spb1_C (PF07780, IPR012920): Spb1 C-terminal domain
DUF3381 (PF11861, IPR024576): Domain of unknown function (DUF3381)
RRP14 (PF15459, IPR029188): 60S ribosome biogenesis protein Rrp14
30 FYTTD1interactor31.0000FYTT (PF07078, IPR009782): Forty-two-three protein
31 GAPDHoncoprotein170.32543.404Gp_dh_C (PF02800, IPR020829): Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain
Gp_dh_N (PF00044, IPR020828, SM00846): Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain
OstA (PF03968, IPR005653): OstA-like protein
32 GARTinteractor150.61015.402AIRS (PF00586, IPR000728): AIR synthase related protein, N-terminal domain
AIRS_C (PF02769, IPR010918): AIR synthase related protein, C-terminal domain
Formyl_trans_N (PF00551, IPR002376): Formyl transferase
GARS_A (PF01071, IPR020561): Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain
GARS_C (PF02843, IPR020560): Phosphoribosylglycinamide synthetase, C domain
GARS_N (PF02844, IPR020562): Phosphoribosylglycinamide synthetase, N domain
33 GZMAinteractor60.4002.471Trypsin (PF00089, IPR001254, SM00020): Trypsin
34 GZMKinteractor30.6670.400Trypsin (PF00089, IPR001254, SM00020): Trypsin
35 HIRIP3interactor80.6075.860CHZ (PF09649, IPR019098, SM01082): Histone chaperone domain CHZ
36 HIST1H1Ainteractor140.25354.586Mucin (PF01456, IPR000458): Mucin-like glycoprotein
Linker_histone (PF00538, IPR005818, SM00526): linker histone H1 and H5 family
CPSF100_C (PF13299, IPR025069): Cleavage and polyadenylation factor 2 C-terminal
37 HIST1H2BAinteractor80.35713.600Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
38 HIST1H3Ainteractor130.24238.071Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
39 HIST3H3interactor130.26939.819Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
40 HIST4H4interactor70.5715.519CENP-T_C (PF15511): Centromere kinetochore component CENP-T histone fold
41 HMGB2interactor100.31119.933HMG_box_2 (PF09011, IPR009071): HMG-box domain
NOA36 (PF06524, IPR010531): NOA36 protein
HMG_box (PF00505, IPR009071, SM00398): HMG (high mobility group) box
42 HSPH1oncoprotein120.56113.690HSP70 (PF00012, IPR013126): Hsp70 protein
SICA_alpha (PF12887, IPR024290): SICA extracellular alpha domain
43 HUWE1oncoprotein150.37426.410BUD22 (PF09073, IPR015158): BUD22
DUF908 (PF06012, IPR010309): Domain of Unknown Function (DUF908)
DUF913 (PF06025, IPR010314): Domain of Unknown Function (DUF913)
FdhE (PF04216, IPR006452): Protein involved in formate dehydrogenase formation
HABP4_PAI-RBP1 (PF04774, IPR006861): Hyaluronan / mRNA binding family
Ku_C (PF03730, IPR005160): Ku70/Ku80 C-terminal arm
Merozoite_SPAM (PF07133, IPR010784): Merozoite surface protein (SPAM)
Mucin (PF01456, IPR000458): Mucin-like glycoprotein
Nop14 (PF04147, IPR007276): Nop14-like family
PBP_sp32 (PF07222, IPR009865): Proacrosin binding protein sp32
RNA_pol_Rpc4 (PF05132, IPR007811): RNA polymerase III RPC4
TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
WWE (PF02825, IPR004170, SM00678): WWE domain
HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
Tim54 (PF11711, IPR021056): Inner membrane protein import complex subunit Tim54
U1snRNP70_N (PF12220, IPR022023): U1 small nuclear ribonucleoprotein of 70kDa MW N terminal
DUF4414 (PF14377, IPR025527): Domain of unknown function (DUF4414)
44 ICAM1oncoprotein60.3333.557Adhes-Ig_like (PF09085, IPR015169): Adhesion molecule, immunoglobulin-like
C2-set_2 (PF08205, IPR013162): CD80-like C2-set immunoglobulin domain
ICAM_N (PF03921, IPR013768): Intercellular adhesion molecule (ICAM), N-terminal domain
Ig_2 (PF13895, IPR007110): Immunoglobulin domain
Ig_3 (PF13927): Immunoglobulin domain
45 IGSF8oncoprotein70.4297.938V-set (PF07686, IPR013106): Immunoglobulin V-set domain
Ig_2 (PF13895, IPR007110): Immunoglobulin domain
Ig_3 (PF13927): Immunoglobulin domain
46 IRF1oncoprotein40.8330.500IRF (PF00605, IPR001346, SM00348): Interferon regulatory factor transcription factor
47 JUNBoncoprotein21.0000bZIP_1 (PF00170, IPR004827): bZIP transcription factor
Jun (PF03957, IPR005643): Jun-like transcription factor
48 KDM5Concoprotein40.6670.286ARID (PF01388, IPR001606, SM00501): ARID/BRIGHT DNA binding domain
JmjC (PF02373, IPR003347, SM00558): JmjC domain, hydroxylase
JmjN (PF02375, IPR003349, SM00545): jmjN domain
PHD (PF00628, IPR019787, SM00249): PHD-finger
PLU-1 (PF08429, IPR013637): PLU-1-like protein
FYVE_2 (PF02318, IPR010911): FYVE-type zinc finger
zf-C5HC2 (PF02928, IPR004198): C5HC2 zinc finger
49 KLF5oncoprotein50.8000.508zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
50 KMT2Aoncoprotein50.5001.086AT_hook (PF02178, IPR017956, SM00384): AT hook motif
DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777)
FYRC (PF05965, IPR003889, SM00542): F/Y rich C-terminus
FYRN (PF05964, IPR003888, SM00541): F/Y-rich N-terminus
Peptidase_S49_N (PF08496, IPR013703): Peptidase family S49 N-terminal
PHD (PF00628, IPR019787, SM00249): PHD-finger
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
RNA_pol_Rpc4 (PF05132, IPR007811): RNA polymerase III RPC4
SET (PF00856, IPR001214, SM00317): SET domain
zf-CXXC (PF02008, IPR002857): CXXC zinc finger domain
SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein
Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
zf-HC5HC2H (PF13771): PHD-like zinc-binding domain
DUF4834 (PF16118, IPR032272): Domain of unknown function (DUF4834)
51 MATR3interactor90.3938.544DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777)
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
zf-U1 (PF06220, IPR013085, SM00451): U1 zinc finger
Tim54 (PF11711, IPR021056): Inner membrane protein import complex subunit Tim54
zf-C2H2_jaz (PF12171, IPR022755): Zinc-finger double-stranded RNA-binding
RRM_5 (PF13893): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
FAM60A (PF15396, IPR026065): Protein Family FAM60A
52 MCM2oncoprotein310.237223.685AAA_3 (PF07726, IPR011703): ATPase family associated with various cellular activities (AAA)
MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family
MCM2_N (PF12619, IPR008045): Mini-chromosome maintenance protein 2
MCM_N (PF14551, IPR027925): MCM N-terminal domain
MCM_OB (PF17207): MCM OB domain
53 MDM2oncoprotein170.28363.167Pinin_SDK_N (PF04697, IPR006787): pinin/SDK conserved region
Presenilin (PF01080, IPR001108): Presenilin
SWIB (PF02201, IPR003121, SM00151): SWIB/MDM2 domain
zf-FPG_IleRS (PF06827, IPR010663): Zinc finger found in FPG and IleRS
zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others
zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
54 MDN1interactor30.6670.500AAA_5 (PF07728, IPR011704): AAA domain (dynein-related subfamily)
DNA_pol_phi (PF04931, IPR007015): DNA polymerase phi
DnaB_C (PF03796, IPR007694): DnaB-like helicase C terminal domain
AAA_16 (PF13191): AAA ATPase domain
Sigma54_activ_2 (PF14532, IPR002078): Sigma-54 interaction domain
55 MEOX2interactor21.0000Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
56 MEPCEinteractor70.6194.700Bin3 (PF06859, IPR010675): Bicoid-interacting protein 3 (Bin3)
Methyltransf_23 (PF13489): Methyltransferase domain
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
DLEU7 (PF15760, IPR031510): Leukemia-associated protein 7
57 MGMTinteractor80.6074.827DNA_binding_1 (PF01035, IPR014048): 6-O-methylguanine DNA methyltransferase, DNA binding domain
Methyltransf_1N (PF02870, IPR008332): 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain
58 MTERF1interactor100mTERF (PF02536, IPR003690, SM00733): mTERF
59 NAP1L1protein found in more fusions120.47316.410NAP (PF00956, IPR002164): Nucleosome assembly protein (NAP)
RNA_pol_3_Rpc31 (PF11705, IPR024661): DNA-directed RNA polymerase III subunit Rpc31
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
60 NME1suppressor50.6671.400NDK (PF00334, IPR001564, SM00562): Nucleoside diphosphate kinase
61 NR3C1protein found in more fusions80.5715.300GCR (PF02155, IPR001409): Glucocorticoid receptor
zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains)
Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
62 NTRK1oncoprotein310.244214.724I-set (PF07679, IPR013098): Immunoglobulin I-set domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
LRR_8 (PF13855, IPR001611): Leucine rich repeat
TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain
63 NUCB1interactor21.0000DUF1104 (PF06518, IPR009488): Protein of unknown function (DUF1104)
Spc24 (PF08286, IPR013252): Spc24 subunit of Ndc80
DUF2967 (PF11179, IPR021349): Protein of unknown function (DUF2967)
DUF3552 (PF12072, IPR022711): Domain of unknown function (DUF3552)
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
64 NUP88interactor21.0000Nup88 (PF10168, IPR019321): Nuclear pore component
65 NUPR1suppressor21.0000Phospho_p8 (PF10195, IPR018792): DNA-binding nuclear phosphoprotein p8
66 OTUD5interactor21.0000OTU (PF02338, IPR003323): OTU-like cysteine protease
Peptidase_C65 (PF10275, IPR019400): Peptidase C65 Otubain
67 PAICSinteractor140.50020.965AIRC (PF00731, IPR000031, SM01001): AIR carboxylase
SAICAR_synt (PF01259, IPR028923): SAICAR synthetase
68 PARK2suppressor100.27816.550IBR (PF01485, IPR002867, SM00647): IBR domain, a half RING-finger domain
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
69 PFN1oncoprotein80.5364.833Profilin (PF00235, IPR005455, SM00392): Profilin
70 PIK3CGinteractor100Myc-LZ (PF02344, IPR003327): Myc leucine zipper domain
PI3K_C2 (PF00792, IPR002420, SM00142): Phosphoinositide 3-kinase C2
PI3K_rbd (PF00794, IPR000341, SM00144): PI3-kinase family, ras-binding domain
PI3Ka (PF00613, IPR001263, SM00145): Phosphoinositide 3-kinase family, accessory domain (PIK domain)
PI3_PI4_kinase (PF00454, IPR000403, SM00146): Phosphatidylinositol 3- and 4-kinase
DUF3244 (PF11589, IPR021638): Domain of unknown function (DUF3244)
DUF4135 (PF13575, IPR025410): Domain of unknown function (DUF4135)
71 PLOD2protein found in more fusions130.6529.5012OG-FeII_Oxy (PF03171, IPR005123): 2OG-Fe(II) oxygenase superfamily
Anp1 (PF03452, IPR005109): Anp1
Glycos_transf_2 (PF00535, IPR001173): Glycosyl transferase family 2
72 PPP2CBsuppressor50.6002.733Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase
STPPase_N (PF16891, IPR031675): Serine-threonine protein phosphatase N-terminal domain
73 PPP2R1Aoncoprotein100.40016.858TAF6_C (PF07571, IPR011442): TAF6 C-terminal HEAT repeat domain
HEAT (PF02985, IPR000357): HEAT repeat
HEAT_PBS (PF03130, IPR004155, SM00567): PBS lyase HEAT-like repeat
HEAT_2 (PF13646): HEAT repeats
74 PRKAR1Aoncoprotein60.6002.008RIIa (PF02197, IPR003117, SM00394): Regulatory subunit of type II PKA R-subunit
cNMP_binding (PF00027, IPR000595, SM00100): Cyclic nucleotide-binding domain
75 PTMAoncoprotein110.36424.949Prothymosin (PF03247, IPR004931): Prothymosin/parathymosin family
76 PTPAoncoprotein40.6671.167PTPA (PF03095, IPR004327): Phosphotyrosyl phosphate activator (PTPA) protein
77 RAC1oncoprotein70.3335.233Ras (PF00071, IPR001806, SM00173): Ras family
78 RANBP3oncoprotein150.57119.697Ran_BP1 (PF00638, IPR000156, SM00160): RanBP1 domain
G_path_suppress (PF15991, IPR026094): G-protein pathway suppressor
79 RGS20interactor100RGS (PF00615, IPR000342, SM00315): Regulator of G protein signaling domain
80 SDCBPinteractor30.6670.500PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
81 SETBP1oncoprotein31.0000AT_hook (PF02178, IPR017956, SM00384): AT hook motif
82 SGO1interactor40.8330.667DUF778 (PF05608, IPR008496): Protein of unknown function (DUF778)
Menin (PF05053, IPR007747): Menin
Shugoshin_C (PF07557, IPR011515): Shugoshin C terminus
Shugoshin_N (PF07558, IPR011516): Shugoshin N-terminal coiled-coil region
83 SOX2oncoprotein90.42912.167HMG_box (PF00505, IPR009071, SM00398): HMG (high mobility group) box
SOXp (PF12336, IPR022097): SOX transcription factor
84 SPATS2Linteractor21.0000DUF1296 (PF06972, IPR009719): Protein of unknown function (DUF1296)
DUF1387 (PF07139, IPR009816): Protein of unknown function (DUF1387)
85 SUB1interactor110.37815.366Dehydrin (PF00257, IPR000167): Dehydrin
PC4 (PF02229, IPR003173): Transcriptional Coactivator p15 (PC4)
86 SUPT5Hinteractor130.53819.351KOW (PF00467, IPR005824, SM00739): KOW motif
Ribonuc_P_40 (PF08584, IPR013893): Ribonuclease P 40kDa (Rpp40) subunit
Spt5-NGN (PF03439, IPR005100): Early transcription elongation factor of RNA pol II, NGN section
Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal
DUF3912 (PF13051, IPR025023): Protein of unknown function (DUF3912)
87 SWAP70oncoprotein90.8331.698DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664)
DUF641 (PF04859, IPR006943): Plant protein of unknown function (DUF641)
GrpE (PF01025, IPR000740): GrpE
PH (PF00169, IPR001849, SM00233): PH domain
CotJB (PF12652, IPR024207): CotJB protein
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
88 TAF1Ainteractor70.5714.452TAF1_subA (PF14929): TAF RNA Polymerase I subunit A
89 TARSinteractor80.7142.027HGTP_anticodon (PF03129, IPR004154): Anticodon binding domain
TGS (PF02824, IPR004095): TGS domain
tRNA-synt_2b (PF00587, IPR002314): tRNA synthetase class II core domain (G, H, P, S and T)
tRNA_SAD (PF07973, IPR012947, SM00863): Threonyl and Alanyl tRNA synthetase second additional domain
90 TERF1interactor170.30852.125TRF (PF08558, IPR013867): Telomere repeat binding factor (TRF)
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
91 TERF2interactor100.5287.855Aconitase_C (PF00694, IPR000573): Aconitase C-terminal domain
TRF (PF08558, IPR013867): Telomere repeat binding factor (TRF)
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
TERF2_RBM (PF16772, IPR031902): Telomeric repeat-binding factor 2 Rap1-binding motif
92 TERF2IPprotein found in more fusions100.5835.821BRF1 (PF07741, IPR011665): Brf1-like TBP-binding domain
Histone_HNS (PF00816, IPR001801): H-NS histone family
Myb_DNA-bind_2 (PF08914, IPR015010): Rap1 Myb domain
Rap1_C (PF11626, IPR021661): TRF2-interacting telomeric protein/Rap1 - C terminal domain
DUF3391 (PF11871, IPR021812): Domain of unknown function (DUF3391)
BRCT_2 (PF16589, IPR001357): BRCT domain, a BRCA1 C-terminus domain
93 THAP7protein found in more fusions40.6670.667THAP (PF05485, IPR006612, SM00980): THAP domain
Tho2 (PF11262, IPR021418): Transcription factor/nuclear export subunit protein 2
94 TP53oncoprotein210.247103.323DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region
P53 (PF00870, IPR011615): P53 DNA-binding domain
P53_tetramer (PF07710, IPR010991): P53 tetramerisation motif
95 TREX1interactor100RNase_T (PF00929, IPR013520): Exonuclease
DUF2733 (PF10813, IPR024360): Protein of unknown function (DUF2733)
PRIMA1 (PF16101): Proline-rich membrane anchor 1
96 TRIM28protein found in more fusions130.33324.646ASFV_J13L (PF05568, IPR008385): African swine fever virus J13L protein
K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain
PHD (PF00628, IPR019787, SM00249): PHD-finger
FYVE_2 (PF02318, IPR010911): FYVE-type zinc finger
zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger
zf-RING_5 (PF14634, IPR001841): zinc-RING finger domain
SKA2 (PF16740, IPR026762): Spindle and kinetochore-associated protein 2
97 UBR5protein found in more fusions80.4298.205CENP-B_dimeris (PF09026, IPR015115): Centromere protein B dimerisation domain
SDA1 (PF05285, IPR007949): SDA1
HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
PABP (PF00658, IPR002004, SM00517): Poly-adenylate binding protein, unique domain
E3_UbLigase_EDD (PF11547, IPR024725): E3 ubiquitin ligase EDD
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
DUF3915 (PF13054, IPR025026): Protein of unknown function (DUF3915)
RCDG1 (PF15725, IPR031457): Renal cancer differentiation gene 1 protein
98 UCHL5oncoprotein90.35712.133Peptidase_C12 (PF01088, IPR001578): Ubiquitin carboxyl-terminal hydrolase, family 1
99 UGP2protein found in more fusions140.64111.698UDPGP (PF01704, IPR002618): UTP--glucose-1-phosphate uridylyltransferase
100 USP17L2interactor100HABP4_PAI-RBP1 (PF04774, IPR006861): Hyaluronan / mRNA binding family
UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase
101 USP46interactor30.6670.500UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase
102 VPS72interactor40.6671.667YL1 (PF05764, IPR008895): YL1 nuclear protein
YL1_C (PF08265, IPR013272, SM00993): YL1 nuclear protein C-terminal domain
103 WDR48suppressor60.4006.867WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
DUF3337 (PF11816, IPR021772): Domain of unknown function (DUF3337)
104 XPO1interactor230.209147.181CRM1_C (PF08767, IPR014877, SM01102): CRM1 C terminal
Hydrolase_3 (PF08282, IPR023214): haloacid dehalogenase-like hydrolase
IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain
Xpo1 (PF08389, IPR013598): Exportin 1-like protein
Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region
105 XRCC6oncoprotein240.253130.762Ku (PF02735, IPR006164, SM00559): Ku70/Ku80 beta-barrel domain
Ku_C (PF03730, IPR005160): Ku70/Ku80 C-terminal arm
Ku_N (PF03731, IPR005161): Ku70/Ku80 N-terminal alpha/beta domain
SAP (PF02037, IPR003034, SM00513): SAP domain

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