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Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

Powered by Cytoscape Web for: parental proteins SELPLG (from a repository: Tue Dec 6 10:32:14 2016)
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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)6
The number (and %) of the onco-proteins2 (33.33 %)
The number (and %) of the tumor suppressors0 (0.00 %)
Total number of binary PPIs (saturation %)10 (66.67 %)
The number (and %) of affected PPIs6 (60.00 %)
The number of possible different fusions3
PPI diameter2
PPI radius1
The average degree of PPI2.000
Assortativity coefficient-0.4472
The network average Clustering coefficient0.350
The number (and %) of a zero Clustering coefficients3 (50.00 %)
The number (and %) of a zero Betweenness Centrality5 (83.33 %)

ACTIVE INTERACTORS


List of the fusions

PPI for parental proteins: SELPLG All fusions
Proteins found in more fusions PIK3R1 (see 1 fusions); SELPLG (see 2 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 SELPLGparental protein60.10018.000EVI2A (PF05399, IPR008608): Ectropic viral integration site 2A protein (EVI2A)
TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
DUF4689 (PF15755, IPR031499): Domain of unknown function (DUF4689)
2 MAGEA1interactor100MAGE (PF01454, IPR002190): MAGE family
MAGE_N (PF12440, IPR021072): Melanoma associated antigen family N terminal
3 MSNoncoprotein200DUF883 (PF05957, IPR010279): Bacterial protein of unknown function (DUF883)
ERM (PF00769, IPR011259): Ezrin/radixin/moesin family
FERM_C (PF09380, IPR018980): FERM C-terminal PH-like domain
FERM_M (PF00373, IPR019748): FERM central domain
FERM_N (PF09379, IPR018979): FERM N-terminal domain
4 PIK3R1oncoprotein31.0000RhoGAP (PF00620, IPR000198, SM00324): RhoGAP domain
SH2 (PF00017, IPR000980, SM00252): SH2 domain
SH3_2 (PF07653, IPR011511): Variant SH3 domain
PI3K_P85_iSH2 (PF16454, IPR032498): Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain
5 SELPinteractor100EGF (PF00008, IPR000742, SM00181): EGF-like domain
Sushi (PF00084, IPR000436, SM00032): Sushi repeat (SCR repeat)
Lectin_C (PF00059, IPR001304, SM00034): Lectin C-type domain
6 TNIP1interactor31.0000ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16)
DUF724 (PF05266, IPR007930): Protein of unknown function (DUF724)
Filament (PF00038, IPR001664): Intermediate filament protein
HALZ (PF02183, IPR003106, SM00340): Homeobox associated leucine zipper
TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein
DUF4201 (PF13870, IPR025254): Domain of unknown function (DUF4201)
FlxA (PF14282, IPR025577): FlxA-like protein
CC2-LZ (PF16516, IPR032419): Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator

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