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Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

Powered by Cytoscape Web for: parental proteins S100A13 (from a repository: Wed Dec 7 06:41:41 2016)
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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)14
The number (and %) of the onco-proteins4 (28.57 %)
The number (and %) of the tumor suppressors0 (0.00 %)
Total number of binary PPIs (saturation %)19 (20.88 %)
The number (and %) of affected PPIs14 (73.68 %)
The number of possible different fusions4
PPI diameter2
PPI radius1
The average degree of PPI2.000
Assortativity coefficient-0.5311
The network average Clustering coefficient0.144
The number (and %) of a zero Clustering coefficients11 (78.57 %)
The number (and %) of a zero Betweenness Centrality13 (92.86 %)

ACTIVE INTERACTORS


List of the fusions

PPI for parental proteins: S100A13 All fusions
: CN281544;
Proteins found in more fusions IL1A (see 1 fusions); NUDT21 (see 2 fusions); S100A13 (see 1 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 S100A13parental protein140.013154.000S_100 (PF01023, IPR013787): S-100/ICaBP type calcium binding domain
2 CEP57interactor100Cep57_MT_bd (PF06657, IPR024957): Centrosome microtubule-binding domain of Cep57
Tup_N (PF08581, IPR013890): Tup N-terminal
CENP-Q (PF13094, IPR025212): CENP-Q, a CENPA-CAD centromere complex subunit
Cep57_CLD (PF14073, IPR025913): Centrosome localisation domain of Cep57
TRIQK (PF15168, IPR024842): Triple QxxK/R motif-containing protein family
3 FGF1oncoprotein31.0000FGF (PF00167, IPR002209, SM00442): Fibroblast growth factor
4 IGBP1interactor100TAP42 (PF04177, IPR007304): TAP42-like family
5 IL1Aprotein found in more fusions200IL1 (PF00340, IPR000975, SM00125): Interleukin-1 / 18
IL1_propep (PF02394, IPR003502): Interleukin-1 propeptide
6 IRF9interactor100IRF (PF00605, IPR001346, SM00348): Interferon regulatory factor transcription factor
IRF-3 (PF10401, IPR019471): Interferon-regulatory factor 3
7 NUDT21protein found in more fusions200NUDIX_2 (PF13869, IPR016706): Nucleotide hydrolase
8 PCYT1Ainteractor100CTP_transf_like (PF01467, IPR004821): Cytidylyltransferase-like
DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664)
9 PHYHIPinteractor100fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
10 PLEKHF2interactor100FYVE (PF01363, IPR000306, SM00064): FYVE zinc finger
PH (PF00169, IPR001849, SM00233): PH domain
11 STK4oncoprotein200Pkinase (PF00069, IPR000719): Protein kinase domain
Mst1_SARAH (PF11629, IPR024205): C terminal SARAH domain of Mst1
DUF4611 (PF15387, IPR027893): Domain of unknown function (DUF4611)
12 SYT1interactor21.0000C2 (PF00168, IPR000008, SM00239): C2 domain
Comm (PF15957, IPR031878): Commissureless
13 THOC7interactor100EcoEI_R_C (PF08463, IPR013670): EcoEI R protein C-terminal
THOC7 (PF05615, IPR008501): Tho complex subunit 7
UPF0193 (PF05250, IPR007914): Uncharacterised protein family (UPF0193)
14 VAT1interactor100ADH_N (PF08240, IPR013154): Alcohol dehydrogenase GroES-like domain
ADH_zinc_N (PF00107, IPR013149): Zinc-binding dehydrogenase
ADH_zinc_N_2 (PF13602): Zinc-binding dehydrogenase

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