Statistic of PPI	Value(s)
The number of interactors (fusion and proteins)	68
The number (and %) of the onco-proteins	49 (72.06 %)
The number (and %) of the tumor suppressors	6 (8.82 %)
Total number of binary PPIs (saturation %)	441 (19.36 %)
The number (and %) of affected PPIs	68 (15.42 %)
The number of possible different fusions	33
PPI diameter	2
PPI radius	1
The average degree of PPI	11.647
Assortativity coefficient	-0.2072
The network average Clustering coefficient	0.551
The number (and %) of a zero Clustering coefficients	4 (5.88 %)
The number (and %) of a zero Betweenness Centrality	10 (14.71 %)

ACTIVE INTERACTORS

List of the fusions
PPI for parental proteins: RUNX1	All fusions : AW847539;
Proteins found in more fusions	RUNX1 (see 1 fusions); CREBBP (see 5 fusions); CTBP1 (see 2 fusions); CREBBP/KAT6A (see 10 fusions); TRAF6 (see 1 fusions); AES (see 3 fusions); UBE2L6 (see 2 fusions); RARA/PML (see 20 fusions); VDR (see 2 fusions); KMT2A (see 16 fusions); CBFA2T2 (see 1 fusions); TCF3 (see 3 fusions); RARA (see 4 fusions); MYOD1 (see 1 fusions); TRIM33 (see 1 fusions); STUB1 (see 1 fusions); HIPK2 (see 1 fusions); TCF12 (see 1 fusions); FOS (see 4 fusions); SMARCC1 (see 2 fusions); RUNX1/CBFA2T2 (see 2 fusions); EP300 (see 1 fusions); SIAH1 (see 1 fusions); PML (see 4 fusions); SUV39H1 (see 1 fusions); SMARCB1 (see 12 fusions); RUNX1T1 (see 1 fusions); RUNX1/RUNX1T1 (see 32 fusions); CDK6 (see 1 fusions); CTBP2 (see 2 fusions); MYC (see 1 fusions); SMAD3 (see 3 fusions);

List of the fusions

PPI for parental proteins: RUNX1

All fusions

: AW847539;

Proteins found in more fusions

RUNX1 (see 1 fusions); CREBBP (see 5 fusions); CTBP1 (see 2 fusions); CREBBP/KAT6A (see 10 fusions); TRAF6 (see 1 fusions); AES (see 3 fusions); UBE2L6 (see 2 fusions); RARA/PML (see 20 fusions); VDR (see 2 fusions); KMT2A (see 16 fusions); CBFA2T2 (see 1 fusions); TCF3 (see 3 fusions); RARA (see 4 fusions); MYOD1 (see 1 fusions); TRIM33 (see 1 fusions); STUB1 (see 1 fusions); HIPK2 (see 1 fusions); TCF12 (see 1 fusions); FOS (see 4 fusions); SMARCC1 (see 2 fusions); RUNX1/CBFA2T2 (see 2 fusions); EP300 (see 1 fusions); SIAH1 (see 1 fusions); PML (see 4 fusions); SUV39H1 (see 1 fusions); SMARCB1 (see 12 fusions); RUNX1T1 (see 1 fusions); RUNX1/RUNX1T1 (see 32 fusions); CDK6 (see 1 fusions); CTBP2 (see 2 fusions); MYC (see 1 fusions); SMAD3 (see 3 fusions);

List of active interactors

#	Name	Type	Number of PPI (degree)	Clustering Coefficient	Betweenness Centrality	Domains (Pfam, InterPro, SMART): description
1	RUNX1	parental protein	68	0.149	2304.921	Runt (PF00853, IPR013524): Runt domain RunxI (PF08504, IPR013711): Runx inhibition domain DUF3037 (PF11236, IPR021398): Protein of unknown function (DUF3037)
2	AES	protein found in more fusions	5	0.500	1.515	TLE_N (PF03920, IPR005617): Groucho/TLE N-terminal Q-rich domain
3	CBFA2T2	protein found in more fusions	8	0.762	1.463	NHR2 (PF08788, IPR014896): NHR2 domain like Remorin_C (PF03763, IPR005516): Remorin, C-terminal region TAFH (PF07531, IPR003894, SM00549): NHR1 homology to TAF zf-MYND (PF01753, IPR002893): MYND finger BBS1 (PF14779, IPR032728): Ciliary BBSome complex subunit 1
4	CBFA2T3	oncoprotein	10	0.622	4.735	NHR2 (PF08788, IPR014896): NHR2 domain like TAFH (PF07531, IPR003894, SM00549): NHR1 homology to TAF zf-MYND (PF01753, IPR002893): MYND finger Efg1 (PF10153, IPR019310): rRNA-processing protein Efg1 PRIMA1 (PF16101): Proline-rich membrane anchor 1
5	CBFB	oncoprotein	6	0.400	5.794	CBF_beta (PF02312, IPR003417): Core binding factor beta subunit
6	CDK1	oncoprotein	5	0.500	0.575	Pkinase (PF00069, IPR000719): Protein kinase domain
7	CDK6	oncoprotein	5	0.833	0.250	Pkinase (PF00069, IPR000719): Protein kinase domain
8	CEBPB	oncoprotein	15	0.670	8.056	RhlB (PF12300, IPR022077): ATP-dependent RNA helicase RhlB FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
9	COPRS	interactor	2	1.000	0	COPR5 (PF15340, IPR029289): Cooperator of PRMT5 family
10	CREBBP	oncoprotein	29	0.415	89.653	Creb_binding (PF09030, IPR014744): Creb binding DUF902 (PF06001, IPR010303): Domain of Unknown Function (DUF902) Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region KIX (PF02172, IPR003101): KIX domain MAS20 (PF02064, IPR002056): MAS20 protein import receptor TPX2 (PF06886, IPR027329): Targeting protein for Xklp2 (TPX2) zf-TAZ (PF02135, IPR000197, SM00551): TAZ zinc finger ANAPC_CDC26 (PF10471, IPR018860): Anaphase-promoting complex APC subunit CDC26 HAT_KAT11 (PF08214, IPR013178): Histone acetylation protein Bromodomain (PF00439, IPR001487, SM00297): Bromodomain ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type DUF3729 (PF12526, IPR022202): Protein of unknown function (DUF3729) DUF4834 (PF16118, IPR032272): Domain of unknown function (DUF4834)
11	CTBP1	protein found in more fusions	14	0.538	14.825	2-Hacid_dh_C (PF02826, IPR006140): D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Cellsynth_D (PF03500, IPR022798): Cellulose synthase subunit D
12	CTBP2	protein found in more fusions	7	0.600	2.900	2-Hacid_dh_C (PF02826, IPR006140): D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
13	DNMT1	oncoprotein	9	0.679	2.518	BAH (PF01426, IPR001025, SM00439): BAH domain DMAP_binding (PF06464, IPR010506, SM01137): DMAP1-binding Domain DNA_methylase (PF00145, IPR001525): C-5 cytosine-specific DNA methylase zf-CXXC (PF02008, IPR002857): CXXC zinc finger domain DNMT1-RFD (PF12047, IPR022702): Cytosine specific DNA methyltransferase replication foci domain
14	ELAVL1	oncoprotein	21	0.242	96.678	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
15	ELF1	interactor	1	0	0	Ets (PF00178, IPR000418, SM00413): Ets-domain PAPA-1 (PF04795, IPR006880): PAPA-1-like conserved region Elf-1_N (PF12310, IPR022084): Transcription factor protein N terminal
16	ELF2	interactor	2	1.000	0	Ets (PF00178, IPR000418, SM00413): Ets-domain Elf-1_N (PF12310, IPR022084): Transcription factor protein N terminal
17	ELF4	oncoprotein	2	1.000	0	Ets (PF00178, IPR000418, SM00413): Ets-domain Elf-1_N (PF12310, IPR022084): Transcription factor protein N terminal
18	EP300	oncoprotein	33	0.252	232.867	Creb_binding (PF09030, IPR014744): Creb binding DUF902 (PF06001, IPR010303): Domain of Unknown Function (DUF902) Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region KIX (PF02172, IPR003101): KIX domain RR_TM4-6 (PF06459, IPR009460): Ryanodine Receptor TM 4-6 TPX2 (PF06886, IPR027329): Targeting protein for Xklp2 (TPX2) zf-TAZ (PF02135, IPR000197, SM00551): TAZ zinc finger HAT_KAT11 (PF08214, IPR013178): Histone acetylation protein Bromodomain (PF00439, IPR001487, SM00297): Bromodomain ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type
19	FHL2	oncoprotein	8	0.762	4.000	LIM (PF00412, IPR001781, SM00132): LIM domain zf-ribbon_3 (PF13248): zinc-ribbon domain
20	FOS	oncoprotein	11	0.689	3.710	bZIP_1 (PF00170, IPR004827): bZIP transcription factor
21	FOXP3	oncoprotein	5	0.600	0.950	Forkhead (PF00250, IPR001766, SM00339): Forkhead domain FOXP-CC (PF16159, IPR032354): FOXP coiled-coil domain
22	HDAC1	suppressor	33	0.327	169.292	FSAP_sig_propep (PF03032, IPR004275): Frog skin active peptide family signal and propeptide Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
23	HDAC11	interactor	3	0.667	1.000	Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
24	HDAC2	oncoprotein	24	0.383	67.843	Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain NARP1 (PF12569, IPR021183): NMDA receptor-regulated protein 1
25	HDAC3	oncoprotein	19	0.438	33.081	Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
26	HIPK2	oncoprotein	9	0.750	3.911	Kdo (PF06293, IPR010440): Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase (PF00069, IPR000719): Protein kinase domain
27	HLA-DMA	interactor	1	0	0	MHC_II_alpha (PF00993, IPR001003, SM00920): Class II histocompatibility antigen, alpha domain C1-set (PF07654, IPR003597, SM00407): Immunoglobulin C1-set domain C1-set_C (PF16196, IPR032431): C1-set C-terminal domain
28	JUN	oncoprotein	20	0.567	22.875	bZIP_1 (PF00170, IPR004827): bZIP transcription factor Jun (PF03957, IPR005643): Jun-like transcription factor
29	KAT6A	oncoprotein	6	0.600	1.561	BUD22 (PF09073, IPR015158): BUD22 MOZ_SAS (PF01853, IPR002717): MOZ/SAS family PHD (PF00628, IPR019787, SM00249): PHD-finger Prothymosin (PF03247, IPR004931): Prothymosin/parathymosin family DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360) Linker_histone (PF00538, IPR005818, SM00526): linker histone H1 and H5 family DUF3306 (PF11748, IPR021735): Protein of unknown function (DUF3306) zf-met (PF12874): Zinc-finger of C2H2 type
30	KAT6B	interactor	1	0	0	Asp-B-Hydro_N (PF05279, IPR007943): Aspartyl beta-hydroxylase N-terminal region DNA_pol_phi (PF04931, IPR007015): DNA polymerase phi DUF1770 (PF08589, IPR013898): Fungal protein of unknown function (DUF1770) MOZ_SAS (PF01853, IPR002717): MOZ/SAS family PHD (PF00628, IPR019787, SM00249): PHD-finger Pro-NT_NN (PF07421, IPR008055): Neurotensin/neuromedin N precursor TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit Bud13 (PF09736, IPR018609): Pre-mRNA-splicing factor of RES complex Linker_histone (PF00538, IPR005818, SM00526): linker histone H1 and H5 family DUF3381 (PF11861, IPR024576): Domain of unknown function (DUF3381) tRNA_bind_2 (PF13725, IPR027992): Possible tRNA binding domain GOLD_2 (PF13897, IPR009038): Golgi-dynamics membrane-trafficking PBP1_TM (PF14812, IPR032730): Transmembrane domain of transglycosylase PBP1 at N-terminal UPF0544 (PF15749, IPR032739): Uncharacterised protein family UPF0544
31	KMT2A	oncoprotein	11	0.556	9.721	AT_hook (PF02178, IPR017956, SM00384): AT hook motif DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777) FYRC (PF05965, IPR003889, SM00542): F/Y rich C-terminus FYRN (PF05964, IPR003888, SM00541): F/Y-rich N-terminus Peptidase_S49_N (PF08496, IPR013703): Peptidase family S49 N-terminal PHD (PF00628, IPR019787, SM00249): PHD-finger Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein RNA_pol_Rpc4 (PF05132, IPR007811): RNA polymerase III RPC4 SET (PF00856, IPR001214, SM00317): SET domain zf-CXXC (PF02008, IPR002857): CXXC zinc finger domain SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein Bromodomain (PF00439, IPR001487, SM00297): Bromodomain zf-HC5HC2H (PF13771): PHD-like zinc-binding domain DUF4834 (PF16118, IPR032272): Domain of unknown function (DUF4834)
32	MYC	oncoprotein	24	0.447	63.795	HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain Myc-LZ (PF02344, IPR003327): Myc leucine zipper domain Myc_N (PF01056, IPR012682): Myc amino-terminal region
33	MYOD1	oncoprotein	11	0.533	8.449	Basic (PF01586, IPR002546, SM00520): Myogenic Basic domain HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain Mfp-3 (PF04202, IPR007328): Foot protein 3 Myf5 (PF12232, IPR022032): Myogenic determination factor 5
34	NCOR1	oncoprotein	22	0.442	49.989	BES1_N (PF05687, IPR008540): BES1/BZR1 plant transcription factor, N-terminal Lamp (PF01299, IPR002000): Lysosome-associated membrane glycoprotein (Lamp) MAS20 (PF02064, IPR002056): MAS20 protein import receptor Neur_chan_memb (PF02932, IPR006029): Neurotransmitter-gated ion-channel transmembrane region Eapp_C (PF10238, IPR019370): E2F-associated phosphoprotein Hid1 (PF12722): High-temperature-induced dauer-formation protein Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain DUF3915 (PF13054, IPR025026): Protein of unknown function (DUF3915) GPS2_interact (PF15784, IPR031557): G-protein pathway suppressor 2-interacting domain DUF4834 (PF16118, IPR032272): Domain of unknown function (DUF4834) RBR (PF17208): RNA binding Region
35	NCOR2	oncoprotein	20	0.511	36.156	CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal MAS20 (PF02064, IPR002056): MAS20 protein import receptor OAD_gamma (PF04277, IPR005899): Oxaloacetate decarboxylase, gamma chain PSK (PF06404, IPR009438): Phytosulfokine precursor protein (PSK) SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360) Gti1_Pac2 (PF09729, IPR018608): Gti1/Pac2 family PRCC (PF10253, IPR018800): Mitotic checkpoint regulator, MAD2B-interacting Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain Spt20 (PF12090, IPR021950): Spt20 family DUF3915 (PF13054, IPR025026): Protein of unknown function (DUF3915) DUF4518 (PF15008, IPR026698): Domain of unknown function (DUF4518) GPS2_interact (PF15784, IPR031557): G-protein pathway suppressor 2-interacting domain DUF4820 (PF16091, IPR032150): Domain of unknown function (DUF4820)
36	NOTCH1	oncoprotein	8	0.762	1.186	Ank (PF00023, IPR002110, SM00248): Ankyrin repeat EGF (PF00008, IPR000742, SM00181): EGF-like domain EGF_2 (PF07974, IPR013111): EGF-like domain EGF_alliinase (PF04863, IPR006947): Alliinase EGF-like domain EGF_CA (PF07645, IPR001881, SM00179): Calcium-binding EGF domain NOD (PF06816, IPR010660): NOTCH protein NODP (PF07684, IPR011656): NOTCH protein TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit Notch (PF00066, IPR000800, SM00004): LNR domain DUF3454 (PF11936, IPR024600): Domain of unknown function (DUF3454) hEGF (PF12661, IPR013032): Human growth factor-like EGF cEGF (PF12662, IPR026823): Complement Clr-like EGF-like Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
37	NR4A2	oncoprotein	5	0.700	1.083	zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
38	PAX5	oncoprotein	2	1.000	0	PAX (PF00292, IPR001523, SM00351): 'Paired box' domain Homeobox (PF00046, IPR001356, SM00389): Homeobox domain Pax2_C (PF12403, IPR022130): Paired-box protein 2 C terminal
39	PML	oncoprotein	25	0.341	117.134	zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger DUF3583 (PF12126, IPR021978): Protein of unknown function (DUF3583) zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
40	PRMT1	interactor	3	1.000	0	Methyltransf_25 (PF13649): Methyltransferase domain
41	RAG1	interactor	2	0	0	zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger) zf-RAG1 (PF10426, IPR019485): Recombination-activating protein 1 zinc-finger domain RAG1_imp_bd (PF12560): RAG1 importin binding RAG1 (PF12940, IPR024627): Recombination-activation protein 1 (RAG1), recombinase
42	RARA	oncoprotein	13	0.606	10.517	zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
43	RBM14	suppressor	4	0.500	2.167	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HnRNPA1 (PF11627, IPR021662): Nuclear factor hnRNPA1
44	RUNX1T1	oncoprotein	16	0.467	21.867	NHR2 (PF08788, IPR014896): NHR2 domain like TAFH (PF07531, IPR003894, SM00549): NHR1 homology to TAF zf-MYND (PF01753, IPR002893): MYND finger DUF3731 (PF12531, IPR021030): DNA-K related protein
45	SIAH1	suppressor	7	0.467	7.400	Sina (PF03145, IPR018121): Seven in absentia protein family
46	SIN3A	oncoprotein	17	0.471	31.964	Sin3_corepress (PF08295, IPR013194, SM00761): Sin3 family co-repressor PAH (PF02671, IPR003822, SM00309): Paired amphipathic helix repeat Sin3a_C (PF16879, IPR031693): C-terminal domain of Sin3a protein
47	SMAD1	interactor	11	0.756	3.638	MH1 (PF03165, IPR003619, SM00523): MH1 domain MH2 (PF03166, IPR001132, SM00524): MH2 domain
48	SMAD2	oncoprotein	20	0.515	29.892	MH1 (PF03165, IPR003619, SM00523): MH1 domain MH2 (PF03166, IPR001132, SM00524): MH2 domain
49	SMAD3	oncoprotein	26	0.387	89.352	MH1 (PF03165, IPR003619, SM00523): MH1 domain MH2 (PF03166, IPR001132, SM00524): MH2 domain
50	SMAD5	interactor	10	0.667	5.026	MH1 (PF03165, IPR003619, SM00523): MH1 domain MH2 (PF03166, IPR001132, SM00524): MH2 domain
51	SMARCA4	oncoprotein	18	0.556	24.419	DUF1840 (PF08895, IPR014991): Domain of unknown function (DUF1840) HSA (PF07529, IPR014012, SM00573): HSA QLQ (PF08880, IPR014978, SM00951): QLQ SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain BRK (PF07533, IPR006576, SM00592): BRK domain Bromodomain (PF00439, IPR001487, SM00297): Bromodomain Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal DUF4065 (PF13274, IPR025272): Protein of unknown function (DUF4065) SnAC (PF14619, IPR029295): Snf2-ATP coupling, chromatin remodelling complex WRNPLPNID (PF15017): Putative WW-binding domain and destruction box
52	SMARCB1	oncoprotein	14	0.718	5.454	SNF5 (PF04855, IPR006939): SNF5 / SMARCB1 / INI1
53	SMARCC1	suppressor	17	0.533	18.987	SWIRM (PF04433, IPR007526): SWIRM domain Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain DUF2618 (PF10940, IPR021237): Protein of unknown function (DUF2618) PTPRCAP (PF15713, IPR016553): Protein tyrosine phosphatase receptor type C-associated SWIRM-assoc_1 (PF16495, IPR032451): SWIRM-associated region 1 SWIRM-assoc_2 (PF16496, IPR032450): SWIRM-associated domain at the N-terminal SWIRM-assoc_3 (PF16498, IPR032448): SWIRM-associated domain at the C-terminal
54	SOX2	oncoprotein	17	0.400	33.213	HMG_box (PF00505, IPR009071, SM00398): HMG (high mobility group) box SOXp (PF12336, IPR022097): SOX transcription factor
55	SPEN	oncoprotein	8	0.643	6.864	ATP-synt_E (PF05680, IPR008386): ATP synthase E chain RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Rxt3 (PF08642, IPR013951): Histone deacetylation protein Rxt3 SPOC (PF07744, IPR012921): SPOC domain DUF4692 (PF15763, IPR031517): Domain of unknown function (DUF4692)
56	SPI1	oncoprotein	9	0.611	3.432	Ets (PF00178, IPR000418, SM00413): Ets-domain p47_phox_C (PF08944, IPR015039): NADPH oxidase subunit p47Phox, C terminal domain
57	STUB1	suppressor	12	0.382	19.540	U-box (PF04564, IPR003613, SM00504): U-box domain ANAPC3 (PF12895): Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 (PF13414, IPR011990): TPR repeat TPR_20 (PF14561): Tetratricopeptide repeat
58	SUV39H1	protein found in more fusions	12	0.491	10.253	Chromo (PF00385, IPR023780, SM00298): Chromo (CHRromatin Organisation MOdifier) domain Pre-SET (PF05033, IPR007728): Pre-SET motif SET (PF00856, IPR001214, SM00317): SET domain
59	TAL1	oncoprotein	13	0.439	15.879	HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain SelK_SelG (PF10961, IPR024491): Selenoprotein SelK_SelG
60	TCF12	oncoprotein	14	0.526	12.349	HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
61	TCF3	oncoprotein	16	0.419	27.791	CDC45 (PF02724, IPR003874): CDC45-like protein HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain DUF3682 (PF12446, IPR022152): Protein of unknown function (DUF3682)
62	TLE1	interactor	5	0.500	1.515	TLE_N (PF03920, IPR005617): Groucho/TLE N-terminal Q-rich domain WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
63	TRAF6	protein found in more fusions	4	0.667	0.400	SlyX (PF04102, IPR007236): SlyX zf-TRAF (PF02176, IPR001293): TRAF-type zinc finger zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
64	TRIM33	oncoprotein	13	0.500	10.768	PHD (PF00628, IPR019787, SM00249): PHD-finger Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein Siva (PF05458, IPR022773): Cd27 binding protein (Siva) Spectrin (PF00435, IPR002017): Spectrin repeat TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger Bromodomain (PF00439, IPR001487, SM00297): Bromodomain zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger
65	UBE2L6	protein found in more fusions	4	0.667	1.000	UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
66	UXT	interactor	2	1.000	0	Prefoldin (PF02996, IPR004127): Prefoldin subunit
67	VDR	suppressor	12	0.691	5.019	zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
68	YAP1	oncoprotein	8	0.643	2.809	Bindin (PF02084, IPR000775): Bindin WW (PF00397, IPR001202, SM00456): WW domain GspL_C (PF12693, IPR025691): GspL periplasmic domain FAM181 (PF15238, IPR029359): FAM181

B a c k t o T o p ⇑

Fusion ID: Protein names:	RUNX1
Level of PPIs:	or Upload text file:	Update repository

Examples	Cytoscape Web will replace the contents your graph	PPI Properties: Click on nodes or edges
Layout Tree Circle Radial Force Directed Preset
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Find Fusion Network

Visualization interactions

Statistics and Network structure information

List of the fusions

List of active interactors