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Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

Powered by Cytoscape Web for: parental proteins MSRB3, RP11-649A16.1 (from a repository: Wed Mar 11 07:26:09 2020)

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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)12
The number (and %) of the onco-proteins1 (8.33 %)
The number (and %) of the tumor suppressors2 (16.67 %)
Total number of binary PPIs (saturation %)17 (25.76 %)
The number (and %) of affected PPIs10 (58.82 %)
The number of possible different fusions2
PPI diameter2
PPI radiusinf
The average degree of PPI2.000
Assortativity coefficient-0.4472
The network average Clustering coefficient0.337
The number (and %) of a zero Clustering coefficients7 (58.33 %)
The number (and %) of a zero Betweenness Centrality11 (91.67 %)


List of the fusions

PPI for parental proteins: MSRB3,RP11-649A16.1 All fusions
Proteins found in more fusions GAPDH (see 5 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Domains (Pfam, InterPro, SMART): description
1 MSRB3parental protein100.04486.000SelR (PF01641, IPR002579): SelR domain
2 RP11-649A16.1interactor000NA
3 AZIN1interactor100Orn_Arg_deC_N (PF02784, IPR022644): Pyridoxal-dependent decarboxylase, pyridoxal binding domain
Orn_DAP_Arg_deC (PF00278, IPR022643): Pyridoxal-dependent decarboxylase, C-terminal sheet domain
4 GAPDHoncoprotein200Gp_dh_C (PF02800, IPR020829): Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain
Gp_dh_N (PF00044, IPR020828, SM00846): Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain
OstA (PF03968, IPR005653): OstA-like protein
5 GOLGA2interactor100ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16)
Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein
Rootletin (PF15035): Ciliary rootlet component, centrosome cohesion
GOLGA2L5 (PF15070, IPR024858): Putative golgin subfamily A member 2-like protein 5
6 LNX2interactor31.0000PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
DZR (PF12773, IPR025874): Double zinc ribbon
zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
7 MAPK8IP2interactor200BUD22 (PF09073, IPR015158): BUD22
CENP-B_dimeris (PF09026, IPR015115): Centromere protein B dimerisation domain
PID (PF00640, IPR006020, SM00462): Phosphotyrosine interaction domain (PTB/PID)
Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal
SH3_9 (PF14604, IPR001452): Variant SH3 domain
8 MOV10interactor21.0000AAA_12 (PF13087): AAA domain
AAA_30 (PF13604): AAA domain
9 NXF1interactor31.0000NTF2 (PF02136, IPR002075): Nuclear transport factor 2 (NTF2) domain
Tap-RNA_bind (PF09162, IPR015245): Tap, RNA-binding
TAP_C (PF03943, IPR005637, SM00804): TAP C-terminal domain
LRR_8 (PF13855, IPR001611): Leucine rich repeat
10 PRDM4suppressor200zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
Ecl1 (PF12855, IPR024368): Life-span regulatory factor
zf-met (PF12874): Zinc-finger of C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
11 TCF4suppressor100CDC45 (PF02724, IPR003874): CDC45-like protein
HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
12 TRIP6interactor21.0000DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region
LIM (PF00412, IPR001781, SM00132): LIM domain

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