1 |
REPS1 | parental protein | 21 | 0.105 | 306.667 | Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator MCLC (PF05934, IPR009231): Mid-1-related chloride channel (MCLC) DUF3123 (PF11321, IPR021470): Protein of unknown function (DUF3123) EF-hand_4 (PF12763, IPR000261): Cytoskeletal-regulatory complex EF hand |
2 |
ABL1 | oncoprotein | 4 | 0.667 | 0.667 | Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain F_actin_bind (PF08919, IPR015015, SM00808): F-actin binding SH3_1 (PF00018, IPR001452, SM00326): SH3 domain FRG2 (PF15315, IPR026245): Facioscapulohumeral muscular dystrophy candidate 2 |
3 |
AMPH | oncoprotein | 5 | 0.700 | 1.833 | BAR (PF03114, IPR004148, SM00721): BAR domain SH3_9 (PF14604, IPR001452): Variant SH3 domain PBP_N (PF17093, IPR031375): Penicillin-binding protein N-terminus |
4 |
AP2M1 | protein found in more fusions | 9 | 0.429 | 14.167 | Adap_comp_sub (PF00928, IPR008968): Adaptor complexes medium subunit family Clat_adaptor_s (PF01217, IPR022775): Clathrin adaptor complex small chain |
5 |
ATF4 | oncoprotein | 2 | 0 | 0 | bZIP_1 (PF00170, IPR004827): bZIP transcription factor |
6 |
CFTR | suppressor | 2 | 0 | 0 | ABC_membrane (PF00664, IPR001140): ABC transporter transmembrane region ABC_tran (PF00005, IPR003439): ABC transporter Roc (PF08477, IPR013684): Ras of Complex, Roc, domain of DAPkinase SMC_N (PF02463, IPR003395): RecF/RecN/SMC N terminal domain Rotamase_2 (PF13145, IPR000297): PPIC-type PPIASE domain CFTR_R (PF14396, IPR025837): Cystic fibrosis TM conductance regulator (CFTR), regulator domain |
7 |
CLTC | oncoprotein | 6 | 0.533 | 5.833 | Clathrin-link (PF09268, IPR015348): Clathrin, heavy-chain linker Clathrin_propel (PF01394, IPR022365): Clathrin propeller repeat Clathrin (PF00637, IPR000547, SM00299): Region in Clathrin and VPS Clathrin_H_link (PF13838): Clathrin-H-link |
8 |
GTSE1 | interactor | 4 | 0.833 | 0.667 | GTSE1_N (PF15259, IPR032768): G-2 and S-phase expressed 1 |
9 |
ITSN1 | interactor | 8 | 0.524 | 8.333 | C2 (PF00168, IPR000008, SM00239): C2 domain VIT1 (PF01988, IPR008217): VIT family DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664) FmdE (PF02663, IPR003814): FmdE, Molybdenum formylmethanofuran dehydrogenase operon GSH_synthase (PF03199, IPR004887): Eukaryotic glutathione synthase RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain EF-hand_4 (PF12763, IPR000261): Cytoskeletal-regulatory complex EF hand DUF3915 (PF13054, IPR025026): Protein of unknown function (DUF3915) SH3_9 (PF14604, IPR001452): Variant SH3 domain DUF4748 (PF15932, IPR031833): Domain of unknown function (DUF4748) INTAP (PF16617): Intersectin and clathrin adaptor AP2 binding region PH_13 (PF16652, IPR001849): Pleckstrin homology domain |
10 |
ITSN2 | protein found in more fusions | 5 | 0.833 | 0.500 | C2 (PF00168, IPR000008, SM00239): C2 domain RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain SH3_2 (PF07653, IPR011511): Variant SH3 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain EF-hand_4 (PF12763, IPR000261): Cytoskeletal-regulatory complex EF hand DUF4407 (PF14362, IPR025519): Domain of unknown function (DUF4407) SH3_9 (PF14604, IPR001452): Variant SH3 domain MRP-S26 (PF14943, IPR026140): Mitochondrial ribosome subunit S26 VIR_N (PF15912, IPR031801): Virilizer, N-terminal PH_13 (PF16652, IPR001849): Pleckstrin homology domain |
11 |
LIMS1 | interactor | 1 | 0 | 0 | LIM (PF00412, IPR001781, SM00132): LIM domain TNFR_c6 (PF00020, IPR001368, SM00208): TNFR/NGFR cysteine-rich region zf-RRN7 (PF11781, IPR021752): Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 |
12 |
LRFN4 | interactor | 1 | 0 | 0 | fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain I-set (PF07679, IPR013098): Immunoglobulin I-set domain LRRCT (PF01463, IPR000483, SM00082): Leucine rich repeat C-terminal domain LRR_8 (PF13855, IPR001611): Leucine rich repeat |
13 |
NTRK1 | oncoprotein | 4 | 0.667 | 0.667 | I-set (PF07679, IPR013098): Immunoglobulin I-set domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase LRR_8 (PF13855, IPR001611): Leucine rich repeat TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain |
14 |
PIN1 | suppressor | 1 | 0 | 0 | Rotamase (PF00639, IPR000297): PPIC-type PPIASE domain WW (PF00397, IPR001202, SM00456): WW domain |
15 |
RAB11FIP2 | protein found in more fusions | 3 | 1.000 | 0 | C2 (PF00168, IPR000008, SM00239): C2 domain RBD-FIP (PF09457, IPR019018): FIP domain |
16 |
RALBP1 | interactor | 4 | 0.833 | 0.667 | DDHD (PF02862, IPR004177, SM01127): DDHD domain RhoGAP (PF00620, IPR000198, SM00324): RhoGAP domain SlyX (PF04102, IPR007236): SlyX Vps39_2 (PF10367, IPR019453): Vacuolar sorting protein 39 domain 2 DUF2968 (PF11180, IPR021350): Protein of unknown function (DUF2968) DUF3505 (PF12013, IPR022698): Protein of unknown function (DUF3505) Nod1 (PF17114, IPR032634): Gef2-related medial cortical node protein Nod1 |
17 |
SGF29 | interactor | 1 | 0 | 0 | DUF1325 (PF07039, IPR010750): SGF29 tudor-like domain Filament (PF00038, IPR001664): Intermediate filament protein |
18 |
SGIP1 | interactor | 3 | 1.000 | 0 | muHD (PF10291, IPR018808): Muniscin C-terminal mu homology domain |
19 |
SLC25A41 | interactor | 3 | 1.000 | 0 | Mito_carr (PF00153, IPR018108): Mitochondrial carrier protein |
20 |
TRAPPC2L | interactor | 2 | 0 | 0 | Sedlin_N (PF04628, IPR006722): Sedlin, N-terminal conserved region |
21 |
WWC2 | interactor | 2 | 0 | 0 | DASH_Dad2 (PF08654, IPR013963): DASH complex subunit Dad2 DUF1840 (PF08895, IPR014991): Domain of unknown function (DUF1840) DUF342 (PF03961, IPR005646): Protein of unknown function (DUF342) Phage_Nu1 (PF07471, IPR010906): Phage DNA packaging protein Nu1 WW (PF00397, IPR001202, SM00456): WW domain |