1 |
RBMX | parental protein | 142 | 0.140 | 9176.290 | RBM1CTR (PF08081, IPR012604): RBM1CTR (NUC064) family RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
2 |
AHSA1 | interactor | 11 | 0.709 | 2.923 | Aha1_N (PF09229, IPR015310, SM01000): Activator of Hsp90 ATPase, N-terminal AHSA1 (PF08327, IPR013538): Activator of Hsp90 ATPase homolog 1-like protein |
3 |
APOBEC3C | interactor | 7 | 0.333 | 6.569 | APOBEC_N (PF08210, IPR013158): APOBEC-like N-terminal domain |
4 |
C10orf2 | interactor | 2 | 1.000 | 0 | T2SSE (PF00437, IPR001482): Type II/IV secretion system protein SMC_N (PF02463, IPR003395): RecF/RecN/SMC N terminal domain AAA_25 (PF13481): AAA domain |
5 |
CAND1 | interactor | 62 | 0.350 | 395.601 | Adaptin_N (PF01602, IPR002553): Adaptin N terminal region DUF1981 (PF09324, IPR015403): Domain of unknown function (DUF1981) HEAT (PF02985, IPR000357): HEAT repeat TIP120 (PF08623, IPR013932): TATA-binding protein interacting (TIP20) RTP1_C1 (PF10363, IPR019451): Required for nuclear transport of RNA pol II C-terminus 1 DUF3385 (PF11865, IPR024585): Domain of unknown function (DUF3385) MMS19_C (PF12460, IPR024687): RNAPII transcription regulator C-terminal Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region HEAT_EZ (PF13513): HEAT-like repeat HEAT_2 (PF13646): HEAT repeats MMS19_N (PF14500): Dos2-interacting transcription regulator of RNA-Pol-II |
6 |
CCDC33 | interactor | 5 | 0.600 | 1.619 | C2 (PF00168, IPR000008, SM00239): C2 domain DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972) Pox_A_type_inc (PF04508, IPR007596): Viral A-type inclusion protein repeat SlyX (PF04102, IPR007236): SlyX |
7 |
CCDC8 | interactor | 24 | 0.553 | 30.267 | Borrelia_P83 (PF05262, IPR007926): Borrelia P83/100 protein SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal PNMA (PF14893, IPR026523): PNMA |
8 |
CDC5L | interactor | 47 | 0.502 | 111.562 | OmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like) Pox_A_type_inc (PF04508, IPR007596): Viral A-type inclusion protein repeat Cir_N (PF10197, IPR019339, SM01083): N-terminal domain of CBF1 interacting co-repressor CIR Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain Myb_Cef (PF11831, IPR021786): pre-mRNA splicing factor component Myb_DNA-bind_6 (PF13921): Myb-like DNA-binding domain |
9 |
CIRBP | oncoprotein | 21 | 0.386 | 51.239 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
10 |
CLK1 | interactor | 15 | 0.538 | 9.240 | PDGF_N (PF04692, IPR006782): Platelet-derived growth factor, N terminal region Pkinase (PF00069, IPR000719): Protein kinase domain |
11 |
CLK3 | interactor | 9 | 0.536 | 7.786 | Pkinase (PF00069, IPR000719): Protein kinase domain SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein |
12 |
CNBP | oncoprotein | 10 | 0.489 | 8.196 | zf-CCHC (PF00098, IPR001878): Zinc knuckle zf-ribbon_3 (PF13248): zinc-ribbon domain |
13 |
CSNK2A1 | oncoprotein | 22 | 0.424 | 26.856 | Pkinase (PF00069, IPR000719): Protein kinase domain |
14 |
CTNNB1 | oncoprotein | 16 | 0.600 | 13.935 | Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat Atx10homo_assoc (PF09759, IPR019156): Spinocerebellar ataxia type 10 protein domain DUF3361 (PF11841, IPR024574): Domain of unknown function (DUF3361) HEAT_EZ (PF13513): HEAT-like repeat |
15 |
CUL3 | protein found in more fusions | 65 | 0.314 | 500.608 | Cullin (PF00888, IPR001373, SM00182): Cullin family Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain WAC_Acf1_DNA_bd (PF10537, IPR013136): ATP-utilising chromatin assembly and remodelling N-terminal |
16 |
CUL7 | protein found in more fusions | 46 | 0.433 | 120.868 | ANAPC10 (PF03256, IPR004939): Anaphase-promoting complex, subunit 10 (APC10) Cullin (PF00888, IPR001373, SM00182): Cullin family DUF1918 (PF08940, IPR015035): Domain of unknown function (DUF1918) Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain Cul7 (PF11515, IPR021097): Mouse development and cellular proliferation protein Cullin-7 |
17 |
DDX5 | oncoprotein | 49 | 0.481 | 123.664 | DEAD (PF00270, IPR011545): DEAD/DEAH box helicase P68HR (PF08061, IPR012587): P68HR (NUC004) repeat ResIII (PF04851, IPR006935): Type III restriction enzyme, res subunit Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain |
18 |
DHX15 | interactor | 43 | 0.492 | 93.047 | DEAD (PF00270, IPR011545): DEAD/DEAH box helicase OB_NTP_bind (PF07717, IPR011709): Oligonucleotide/oligosaccharide-binding (OB)-fold DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777) HA2 (PF04408, IPR007502, SM00847): Helicase associated domain (HA2) Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain AAA_29 (PF13555): P-loop containing region of AAA domain |
19 |
DHX36 | interactor | 11 | 0.509 | 4.744 | DEAD (PF00270, IPR011545): DEAD/DEAH box helicase OB_NTP_bind (PF07717, IPR011709): Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 (PF04408, IPR007502, SM00847): Helicase associated domain (HA2) Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain |
20 |
EED | suppressor | 41 | 0.412 | 138.536 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160 ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain |
21 |
EEF1A1 | suppressor | 34 | 0.428 | 73.501 | GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2 GTP_EFTU_D3 (PF03143, IPR004160): Elongation factor Tu C-terminal domain |
22 |
EIF4A3 | interactor | 48 | 0.500 | 124.541 | DEAD (PF00270, IPR011545): DEAD/DEAH box helicase Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain |
23 |
ELAVL2 | interactor | 4 | 1.000 | 0 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
24 |
ESR1 | suppressor | 33 | 0.458 | 72.478 | Oest_recep (PF02159, IPR001292): Oestrogen receptor zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor ESR1_C (PF12743, IPR024736): Oestrogen-type nuclear receptor final C-terminal |
25 |
FAM103A1 | interactor | 4 | 0.667 | 0.800 | RAM (PF15320, IPR028271): mRNA cap methylation, RNMT-activating mini protein |
26 |
FAM120A | interactor | 14 | 0.648 | 4.289 | TPR_15 (PF13429): Tetratricopeptide repeat |
27 |
FASTKD2 | interactor | 3 | 1.000 | 0 | FAST_1 (PF06743, IPR010622): FAST kinase-like protein, subdomain 1 FAST_2 (PF08368, IPR013579): FAST kinase-like protein, subdomain 2 RAP (PF08373, IPR013584, SM00952): RAP domain |
28 |
FBXO6 | interactor | 21 | 0.529 | 22.936 | FBA (PF04300, IPR007397): F-box associated region F-box-like (PF12937, IPR001810): F-box-like |
29 |
FBXW11 | interactor | 26 | 0.307 | 83.568 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Beta-TrCP_D (PF12125, IPR021977, SM01028): D domain of beta-TrCP ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain F-box-like (PF12937, IPR001810): F-box-like |
30 |
FBXW7 | suppressor | 7 | 0.533 | 1.384 | Mem_trans (PF03547, IPR004776): Membrane transport protein WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160 F-box-like (PF12937, IPR001810): F-box-like |
31 |
FN1 | oncoprotein | 40 | 0.387 | 149.418 | fn1 (PF00039, IPR000083, SM00058): Fibronectin type I domain fn2 (PF00040, IPR000562, SM00059): Fibronectin type II domain fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369) |
32 |
FOXL2 | suppressor | 2 | 1.000 | 0 | K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain Forkhead (PF00250, IPR001766, SM00339): Forkhead domain PRIMA1 (PF16101): Proline-rich membrane anchor 1 |
33 |
FOXM1 | oncoprotein | 1 | 0 | 0 | EspF (PF04806, IPR006891): EspF protein repeat Forkhead (PF00250, IPR001766, SM00339): Forkhead domain |
34 |
FOXS1 | interactor | 2 | 1.000 | 0 | Forkhead (PF00250, IPR001766, SM00339): Forkhead domain |
35 |
FUS | suppressor | 38 | 0.450 | 90.743 | Herpes_PAP (PF03325, IPR004997): Herpesvirus polymerase accessory protein RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SVS_QK (PF10578, IPR018942): Seminal vesicle protein repeat zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others Limkain-b1 (PF11608, IPR024582): Limkain b1 FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 Keratin_2_head (PF16208, IPR032444): Keratin type II head |
36 |
FXR2 | interactor | 11 | 0.444 | 13.765 | Agenet (PF05641, IPR008395, SM00743): Agenet domain REV (PF00424, IPR000625): REV protein (anti-repression trans-activator protein) KH_1 (PF00013, IPR004088, SM00322): KH domain FXMRP1_C_core (PF12235, IPR022034): Fragile X-related 1 protein core C terminal FXR_C1 (PF16096, IPR032172): Fragile X-related 1 protein C-terminal region 2 |
37 |
GID8 | interactor | 2 | 0 | 0 | LisH (PF08513, IPR013720, SM00667): LisH CLTH (PF10607, IPR024964): CTLH/CRA C-terminal to LisH motif domain |
38 |
GSTP1 | suppressor | 12 | 0.636 | 2.003 | GST_N (PF02798, IPR004045): Glutathione S-transferase, N-terminal domain GST_C_3 (PF14497, IPR004046): Glutathione S-transferase, C-terminal domain |
39 |
HDAC5 | protein found in more fusions | 23 | 0.593 | 12.618 | Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain NOA36 (PF06524, IPR010531): NOA36 protein Activator_LAG-3 (PF11498, IPR021587): Transcriptional activator LAG-3 HDAC4_Gln (PF12203, IPR024643): Glutamine rich N terminal domain of histone deacetylase 4 |
40 |
HDGF | interactor | 8 | 0.821 | 0.472 | PWWP (PF00855, IPR000313, SM00293): PWWP domain |
41 |
HNRNPA0 | interactor | 38 | 0.556 | 53.943 | SAP130_C (PF16014, IPR031963): Histone deacetylase complex subunit SAP130 C-terminus |
42 |
HNRNPA1 | interactor | 80 | 0.282 | 1006.446 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HnRNPA1 (PF11627, IPR021662): Nuclear factor hnRNPA1 |
43 |
HNRNPC | protein found in more fusions | 49 | 0.376 | 193.405 | APG6 (PF04111, IPR007243): Autophagy protein Apg6 RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SURF2 (PF05477, IPR008833): Surfeit locus protein 2 (SURF2) |
44 |
HNRNPD | oncoprotein | 44 | 0.396 | 156.084 | CBFNT (PF08143, IPR012956): CBFNT (NUC161) domain NID (PF07292, IPR009909): Nmi/IFP 35 domain (NID) RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Keratin_2_head (PF16208, IPR032444): Keratin type II head |
45 |
HNRNPF | interactor | 41 | 0.532 | 78.269 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Spot_14 (PF07084, IPR009786): Thyroid hormone-inducible hepatic protein Spot 14 zf-RNPHF (PF08080, IPR012996): RNPHF zinc finger |
46 |
HNRNPH1 | oncoprotein | 43 | 0.517 | 80.533 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RNPHF (PF08080, IPR012996): RNPHF zinc finger |
47 |
HNRNPH2 | interactor | 32 | 0.557 | 39.661 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RNPHF (PF08080, IPR012996): RNPHF zinc finger |
48 |
HNRNPK | oncoprotein | 64 | 0.364 | 486.123 | ROKNT (PF08067, IPR012987): ROKNT (NUC014) domain KH_1 (PF00013, IPR004088, SM00322): KH domain |
49 |
HNRNPM | interactor | 46 | 0.495 | 109.176 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HnRNP_M (PF11532, IPR024666): Heterogeneous nuclear ribonucleoprotein M Collagen_mid (PF15984, IPR031929): Bacterial collagen, middle region |
50 |
HNRNPR | interactor | 53 | 0.454 | 186.147 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 (PF11608, IPR024582): Limkain b1 |
51 |
HNRNPUL1 | interactor | 31 | 0.393 | 72.960 | Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator Rox3 (PF08633, IPR013942): Rox3 mediator complex subunit SAP (PF02037, IPR003034, SM00513): SAP domain SPRY (PF00622, IPR003877, SM00449): SPRY domain AAA_33 (PF13671): AAA domain PRIMA1 (PF16101): Proline-rich membrane anchor 1 |
52 |
HPD | interactor | 1 | 0 | 0 | Glyoxalase (PF00903, IPR004360): Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 (PF13468, IPR025870): Glyoxalase-like domain |
53 |
IFIT3 | interactor | 6 | 0.600 | 0.461 | TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat TPR_10 (PF13374, IPR011990): Tetratricopeptide repeat TPR_12 (PF13424): Tetratricopeptide repeat TPR_17 (PF13431): Tetratricopeptide repeat TPR_19 (PF14559): Tetratricopeptide repeat |
54 |
IL7R | interactor | 19 | 0.339 | 23.748 | fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain |
55 |
ITGA4 | interactor | 32 | 0.516 | 50.000 | FG-GAP (PF01839, IPR013517): FG-GAP repeat Integrin_alpha (PF00357, IPR018184): Integrin alpha cytoplasmic region Integrin_alpha2 (PF08441, IPR013649): Integrin alpha |
56 |
ITSN2 | protein found in more fusions | 5 | 0.667 | 0.800 | C2 (PF00168, IPR000008, SM00239): C2 domain RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain SH3_2 (PF07653, IPR011511): Variant SH3 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain EF-hand_4 (PF12763, IPR000261): Cytoskeletal-regulatory complex EF hand DUF4407 (PF14362, IPR025519): Domain of unknown function (DUF4407) SH3_9 (PF14604, IPR001452): Variant SH3 domain MRP-S26 (PF14943, IPR026140): Mitochondrial ribosome subunit S26 VIR_N (PF15912, IPR031801): Virilizer, N-terminal PH_13 (PF16652, IPR001849): Pleckstrin homology domain |
57 |
IVNS1ABP | protein found in more fusions | 14 | 0.641 | 5.861 | BACK (PF07707, IPR011705, SM00875): BTB And C-terminal Kelch BTB (PF00651, IPR013069, SM00225): BTB/POZ domain Kelch_1 (PF01344, IPR006652, SM00612): Kelch motif |
58 |
JAK2 | oncoprotein | 5 | 0.500 | 2.667 | FERM_M (PF00373, IPR019748): FERM central domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain |
59 |
KHDRBS1 | protein found in more fusions | 32 | 0.477 | 71.088 | KH_1 (PF00013, IPR004088, SM00322): KH domain Qua1 (PF16274, IPR032571): Qua1 domain Sam68-YY (PF16568, IPR032335): Tyrosine-rich domain of Sam68 |
60 |
KHDRBS2 | interactor | 21 | 0.426 | 43.207 | KH_1 (PF00013, IPR004088, SM00322): KH domain Qua1 (PF16274, IPR032571): Qua1 domain Sam68-YY (PF16568, IPR032335): Tyrosine-rich domain of Sam68 |
61 |
KHDRBS3 | interactor | 16 | 0.381 | 35.675 | KH_1 (PF00013, IPR004088, SM00322): KH domain Qua1 (PF16274, IPR032571): Qua1 domain Sam68-YY (PF16568, IPR032335): Tyrosine-rich domain of Sam68 |
62 |
LNX1 | interactor | 7 | 0.400 | 6.183 | PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) zf-rbx1 (PF12678, IPR024766): RING-H2 zinc finger domain zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger) |
63 |
LUZP4 | interactor | 12 | 0.455 | 6.929 | Pox_Ag35 (PF03286, IPR004966): Pox virus Ag35 surface protein ANAPC_CDC26 (PF10471, IPR018860): Anaphase-promoting complex APC subunit CDC26 DUF2570 (PF10828, IPR022538): Protein of unknown function (DUF2570) |
64 |
MAGOH | interactor | 27 | 0.504 | 32.881 | Mago_nashi (PF02792, IPR004023): Mago nashi protein |
65 |
MAGOHB | interactor | 4 | 0.500 | 0.545 | Mago_nashi (PF02792, IPR004023): Mago nashi protein |
66 |
MALSU1 | interactor | 2 | 1.000 | 0 | RsfS (PF02410, IPR025656): Ribosomal silencing factor during starvation |
67 |
MATR3 | interactor | 45 | 0.451 | 129.217 | DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777) RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-U1 (PF06220, IPR013085, SM00451): U1 zinc finger Tim54 (PF11711, IPR021056): Inner membrane protein import complex subunit Tim54 zf-C2H2_jaz (PF12171, IPR022755): Zinc-finger double-stranded RNA-binding RRM_5 (PF13893): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FAM60A (PF15396, IPR026065): Protein Family FAM60A |
68 |
MCAT | interactor | 2 | 1.000 | 0 | Acyl_transf_1 (PF00698, IPR014043): Acyl transferase domain |
69 |
MCM2 | oncoprotein | 44 | 0.403 | 185.302 | AAA_3 (PF07726, IPR011703): ATPase family associated with various cellular activities (AAA) MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family MCM2_N (PF12619, IPR008045): Mini-chromosome maintenance protein 2 MCM_N (PF14551, IPR027925): MCM N-terminal domain MCM_OB (PF17207): MCM OB domain |
70 |
MCM5 | oncoprotein | 23 | 0.589 | 13.662 | MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family MCM_N (PF14551, IPR027925): MCM N-terminal domain MCM_OB (PF17207): MCM OB domain |
71 |
MEPCE | interactor | 16 | 0.800 | 2.383 | Bin3 (PF06859, IPR010675): Bicoid-interacting protein 3 (Bin3) Methyltransf_23 (PF13489): Methyltransferase domain FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 DLEU7 (PF15760, IPR031510): Leukemia-associated protein 7 |
72 |
MTERF3 | interactor | 5 | 0.700 | 1.278 | mTERF (PF02536, IPR003690, SM00733): mTERF Pex14_N (PF04695, IPR006785): Peroxisomal membrane anchor protein (Pex14p) conserved region |
73 |
NABP1 | interactor | 4 | 0.500 | 1.833 | tRNA_anti-codon (PF01336, IPR004365): OB-fold nucleic acid binding domain |
74 |
NCOA5 | suppressor | 14 | 0.397 | 21.808 | Macoilin (PF09726, IPR019130): Transmembrane protein |
75 |
NFE2L2 | oncoprotein | 4 | 0.667 | 1.105 | bZIP_Maf (PF03131, IPR004826): bZIP Maf transcription factor |
76 |
NGRN | interactor | 2 | 1.000 | 0 | Neugrin (PF06413, IPR010487): Neugrin |
77 |
NIF3L1 | interactor | 3 | 1.000 | 0 | NIF3 (PF01784, IPR002678): NIF3 (NGG1p interacting factor 3) |
78 |
NTRK1 | oncoprotein | 57 | 0.360 | 299.113 | I-set (PF07679, IPR013098): Immunoglobulin I-set domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase LRR_8 (PF13855, IPR001611): Leucine rich repeat TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain |
79 |
NUCKS1 | interactor | 1 | 0 | 0 | FYDLN_acid (PF09538, IPR012644): Protein of unknown function (FYDLN_acid) XRCC4 (PF06632, IPR010585): DNA double-strand break repair and V(D)J recombination protein XRCC4 PBP1_TM (PF14812, IPR032730): Transmembrane domain of transglycosylase PBP1 at N-terminal CCSAP (PF15748, IPR029774): Centriole, cilia and spindle-associated |
80 |
NXF1 | interactor | 35 | 0.383 | 111.712 | NTF2 (PF02136, IPR002075): Nuclear transport factor 2 (NTF2) domain Tap-RNA_bind (PF09162, IPR015245): Tap, RNA-binding TAP_C (PF03943, IPR005637, SM00804): TAP C-terminal domain LRR_8 (PF13855, IPR001611): Leucine rich repeat |
81 |
OBSL1 | interactor | 46 | 0.439 | 102.603 | BiPBP_C (PF06832, IPR009647): Penicillin-Binding Protein C-terminus Family fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain Herpes_gE (PF02480, IPR003404): Alphaherpesvirus glycoprotein E I-set (PF07679, IPR013098): Immunoglobulin I-set domain V-set (PF07686, IPR013106): Immunoglobulin V-set domain Ig_3 (PF13927): Immunoglobulin domain Ig_4 (PF16680, IPR032052): T-cell surface glycoprotein CD3 delta chain Izumo-Ig (PF16706, IPR032699): Izumo-like Immunoglobulin domain |
82 |
P3H2 | interactor | 1 | 0 | 0 | TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat TPR_16 (PF13432): Tetratricopeptide repeat YfiO (PF13525): Outer membrane lipoprotein 2OG-FeII_Oxy_3 (PF13640, IPR005123): 2OG-Fe(II) oxygenase superfamily Fis1_TPR_C (PF14853, IPR028061): Fis1 C-terminal tetratricopeptide repeat |
83 |
PAIP1 | interactor | 5 | 1.000 | 0 | MIF4G (PF02854, IPR003890, SM00543): MIF4G domain PAM2 (PF07145, IPR009818): Ataxin-2 C-terminal region |
84 |
PAN2 | interactor | 14 | 0.462 | 14.203 | RNase_T (PF00929, IPR013520): Exonuclease UCH_1 (PF13423, IPR001394): Ubiquitin carboxyl-terminal hydrolase WD40_like (PF17005, IPR031544): WD40-like domain |
85 |
PPP1CB | interactor | 17 | 0.338 | 34.064 | Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase STPPase_N (PF16891, IPR031675): Serine-threonine protein phosphatase N-terminal domain |
86 |
PPP1CC | oncoprotein | 11 | 0.291 | 21.716 | Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase STPPase_N (PF16891, IPR031675): Serine-threonine protein phosphatase N-terminal domain |
87 |
PPP2R1A | oncoprotein | 20 | 0.458 | 29.881 | TAF6_C (PF07571, IPR011442): TAF6 C-terminal HEAT repeat domain HEAT (PF02985, IPR000357): HEAT repeat HEAT_PBS (PF03130, IPR004155, SM00567): PBS lyase HEAT-like repeat HEAT_2 (PF13646): HEAT repeats |
88 |
PRR3 | interactor | 7 | 0.619 | 3.486 | zf-CCCH (PF00642, IPR000571): Zinc finger C-x8-C-x5-C-x3-H type (and similar) |
89 |
PSMF1 | interactor | 4 | 0.667 | 0.500 | PI31_Prot_C (PF08577, IPR013886): PI31 proteasome regulator PI31_Prot_N (PF11566, IPR021625): PI31 proteasome regulator N-terminal |
90 |
PTCD1 | interactor | 5 | 0.700 | 0.511 | PPR_2 (PF13041, IPR002885): PPR repeat family PPR_3 (PF13812, IPR002885): Pentatricopeptide repeat domain PPR_long (PF17177): Pentacotripeptide-repeat region of PROPR |
91 |
QKI | protein found in more fusions | 13 | 0.439 | 20.051 | KH_1 (PF00013, IPR004088, SM00322): KH domain STAR_dimer (PF16544, IPR032377): Homodimerisation region of STAR domain protein Quaking_NLS (PF16551, IPR032367): Putative nuclear localisation signal of quaking |
92 |
RAC1 | oncoprotein | 7 | 0.733 | 0.408 | Ras (PF00071, IPR001806, SM00173): Ras family |
93 |
RALY | interactor | 28 | 0.566 | 79.936 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SelK_SelG (PF10961, IPR024491): Selenoprotein SelK_SelG |
94 |
RB1CC1 | suppressor | 5 | 0.600 | 1.143 | Arc_PepC_II (PF06847, IPR009655): Archaeal Peptidase A24 C-terminus Type II DHC (PF09626, IPR018588): Dihaem cytochrome c DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972) FlaC_arch (PF05377, IPR008039): Flagella accessory protein C (FlaC) ATG11 (PF10377, IPR019460): Autophagy-related protein 11 DUF4407 (PF14362, IPR025519): Domain of unknown function (DUF4407) Jag_N (PF14804, IPR032782): Jag N-terminus NPBW (PF15180, IPR013297): Neuropeptides B and W HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1 BST2 (PF16716, IPR024886): Bone marrow stromal antigen 2 Goodbye (PF17109, IPR031350): fungal STAND N-terminal Goodbye domain |
95 |
RBM14 | suppressor | 28 | 0.479 | 38.091 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HnRNPA1 (PF11627, IPR021662): Nuclear factor hnRNPA1 |
96 |
RBM3 | interactor | 15 | 0.524 | 16.296 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
97 |
RBM45 | interactor | 8 | 0.810 | 2.667 | RNA_bind (PF08675, IPR014789): RNA binding domain RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
98 |
RBM7 | interactor | 14 | 0.538 | 14.377 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
99 |
RBM8A | interactor | 17 | 0.517 | 17.902 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
100 |
RBMY1A1 | interactor | 9 | 0.393 | 10.048 | RBM1CTR (PF08081, IPR012604): RBM1CTR (NUC064) family RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sulfakinin (PF08257, IPR013259): Sulfakinin family BMP2K_C (PF15282, IPR028182): BMP-2-inducible protein kinase C-terminus |
101 |
RBMY1F | interactor | 10 | 0.333 | 13.548 | RBM1CTR (PF08081, IPR012604): RBM1CTR (NUC064) family RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sulfakinin (PF08257, IPR013259): Sulfakinin family |
102 |
RNF2 | interactor | 33 | 0.403 | 71.819 | zf-C4_Topoisom (PF01396, IPR013498): Topoisomerase DNA binding C4 zinc finger zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger) RAWUL (PF16207, IPR032443): RAWUL domain RING finger- and WD40-associated ubiquitin-like |
103 |
ROBO3 | interactor | 2 | 1.000 | 0 | Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain Herpes_gE (PF02480, IPR003404): Alphaherpesvirus glycoprotein E I-set (PF07679, IPR013098): Immunoglobulin I-set domain V-set (PF07686, IPR013106): Immunoglobulin V-set domain Ig_3 (PF13927): Immunoglobulin domain Pur_ac_phosph_N (PF16656, IPR015914): Purple acid Phosphatase, N-terminal domain |
104 |
RPL31 | interactor | 18 | 0.503 | 17.510 | Ribosomal_L31e (PF01198, IPR000054): Ribosomal protein L31e |
105 |
RPS28 | interactor | 12 | 0.652 | 2.580 | Ribosomal_S28e (PF01200, IPR000289): Ribosomal protein S28e |
106 |
RPSA | interactor | 29 | 0.433 | 54.793 | Ribosomal_S2 (PF00318, IPR001865): Ribosomal protein S2 40S_SA_C (PF16122, IPR032281): 40S ribosomal protein SA C-terminus |
107 |
RRM2 | interactor | 2 | 1.000 | 0 | Ribonuc_red_sm (PF00268, IPR000358): Ribonucleotide reductase, small chain |
108 |
SAFB | suppressor | 26 | 0.385 | 73.122 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SAP (PF02037, IPR003034, SM00513): SAP domain Ferlin_C (PF16165, IPR032362): Ferlin C-terminus |
109 |
SAFB2 | suppressor | 16 | 0.500 | 23.669 | LicD (PF04991, IPR007074): LicD family Pinin_SDK_memA (PF04696, IPR006786): pinin/SDK/memA/ protein conserved region RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SAP (PF02037, IPR003034, SM00513): SAP domain DUF4228 (PF14009, IPR025322): Domain of unknown function (DUF4228) Ferlin_C (PF16165, IPR032362): Ferlin C-terminus |
110 |
SCARNA22 | interactor | 17 | 0.676 | 4.070 | NA |
111 |
SF3A1 | interactor | 37 | 0.538 | 52.809 | TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit Surp (PF01805, IPR000061, SM00648): Surp module ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family PRP21_like_P (PF12230, IPR022030): Pre-mRNA splicing factor PRP21 like protein |
112 |
SF3A2 | interactor | 29 | 0.525 | 51.593 | Cytadhesin_P30 (PF07271, IPR009896): Cytadhesin P30/P32 PRP4 (PF08799, IPR014906): pre-mRNA processing factor 4 (PRP4) like Totivirus_coat (PF05518, IPR008871): Totivirus coat protein zf-met (PF12874): Zinc-finger of C2H2 type ARL6IP6 (PF15062, IPR029383): Haemopoietic lineage transmembrane helix SF3A2 (PF16835, IPR031781): Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) |
113 |
SF3B1 | oncoprotein | 45 | 0.436 | 112.495 | Dopey_N (PF04118, IPR007249): Dopey, N-terminal HEAT (PF02985, IPR000357): HEAT repeat SF3b1 (PF08920, IPR015016): Splicing factor 3B subunit 1 UNC45-central (PF11701, IPR024660): Myosin-binding striated muscle assembly central Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region HEAT_EZ (PF13513): HEAT-like repeat HEAT_2 (PF13646): HEAT repeats |
114 |
SF3B2 | interactor | 32 | 0.460 | 54.858 | DUF382 (PF04037, IPR007180): Domain of unknown function (DUF382) PAPA-1 (PF04795, IPR006880): PAPA-1-like conserved region PSP (PF04046, IPR006568, SM00581): PSP SAP (PF02037, IPR003034, SM00513): SAP domain Usp (PF00582, IPR006016): Universal stress protein family Med19 (PF10278, IPR019403): Mediator of RNA pol II transcription subunit 19 Vma12 (PF11712, IPR021013): Endoplasmic reticulum-based factor for assembly of V-ATPase FAM176 (PF14851): FAM176 family WRNPLPNID (PF15017): Putative WW-binding domain and destruction box |
115 |
SF3B3 | interactor | 37 | 0.521 | 69.274 | CPSF_A (PF03178, IPR004871): CPSF A subunit region MMS1_N (PF10433): Mono-functional DNA-alkylating methyl methanesulfonate N-term |
116 |
SF3B4 | interactor | 22 | 0.571 | 22.256 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
117 |
SF3B6 | interactor | 21 | 0.514 | 20.052 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
118 |
SIRT7 | interactor | 28 | 0.307 | 77.586 | DUF563 (PF04577, IPR007657): Protein of unknown function (DUF563) SIR2 (PF02146, IPR003000): Sir2 family |
119 |
SNRPA | interactor | 26 | 0.483 | 40.787 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
120 |
SNW1 | protein found in more fusions | 41 | 0.565 | 83.168 | SKIP_SNW (PF02731, IPR004015): SKIP/SNW domain PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term SIR4_SID (PF16991, IPR031556): Sir4 SID domain |
121 |
SOCS3 | suppressor | 2 | 1.000 | 0 | SH2 (PF00017, IPR000980, SM00252): SH2 domain SOCS_box (PF07525, IPR001496): SOCS box |
122 |
SORBS3 | interactor | 5 | 0.667 | 0.273 | Sorb (PF02208, IPR003127, SM00459): Sorbin homologous domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain SH3_9 (PF14604, IPR001452): Variant SH3 domain |
123 |
SPICE1 | interactor | 4 | 0.500 | 1.889 | SPICE (PF15678, IPR031387): Centriole duplication and mitotic chromosome congression ANXA2R (PF15721, IPR031449): Annexin-2 receptor JIP_LZII (PF16471, IPR032486): JNK-interacting protein leucine zipper II |
124 |
SREK1 | protein found in more fusions | 15 | 0.527 | 8.341 | Ureide_permease (PF07168, IPR009834): Ureide permease RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RP-C_C (PF11800, IPR021760): Replication protein C C-terminal region PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term DUF3915 (PF13054, IPR025026): Protein of unknown function (DUF3915) BRD4_CDT (PF17105, IPR031354): C-terminal domain of bromodomain protein 4 |
125 |
SRPK2 | oncoprotein | 34 | 0.432 | 122.973 | DUF1387 (PF07139, IPR009816): Protein of unknown function (DUF1387) Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator Pkinase (PF00069, IPR000719): Protein kinase domain S-antigen (PF05756, IPR008825): S-antigen protein DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360) |
126 |
SRPK3 | interactor | 11 | 0.564 | 3.963 | Herpes_capsid (PF06112, IPR009299): Gammaherpesvirus capsid protein Pkinase (PF00069, IPR000719): Protein kinase domain |
127 |
SRRM1 | interactor | 31 | 0.499 | 50.586 | DUF1754 (PF08555, IPR013865): Eukaryotic family of unknown function (DUF1754) ETRAMP (PF09716, IPR006389): Malarial early transcribed membrane protein (ETRAMP) Hepatitis_core (PF00906, IPR002006): Hepatitis core antigen MAP65_ASE1 (PF03999, IPR007145): Microtubule associated protein (MAP65/ASE1 family) PWI (PF01480, IPR002483, SM00311): PWI domain Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein |
128 |
SRRM2 | interactor | 40 | 0.492 | 107.604 | cwf21 (PF08312, IPR013170, SM01115): cwf21 domain DUF1754 (PF08555, IPR013865): Eukaryotic family of unknown function (DUF1754) Pap_E4 (PF02711, IPR003861): E4 protein RR_TM4-6 (PF06459, IPR009460): Ryanodine Receptor TM 4-6 CTD (PF12815, IPR024945, SM01104): Spt5 C-terminal nonapeptide repeat binding Spt4 DUF4614 (PF15391, IPR027884): Domain of unknown function (DUF4614) |
129 |
STAT5A | suppressor | 6 | 0.400 | 4.433 | SH2 (PF00017, IPR000980, SM00252): SH2 domain STAT_alpha (PF01017, IPR013800): STAT protein, all-alpha domain STAT_bind (PF02864, IPR013801): STAT protein, DNA binding domain STAT_int (PF02865, IPR013799, SM00964): STAT protein, protein interaction domain |
130 |
STAU1 | protein found in more fusions | 36 | 0.518 | 69.406 | dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif Staufen_C (PF16482, IPR032478): Staufen C-terminal domain |
131 |
TARDBP | interactor | 42 | 0.474 | 117.147 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
132 |
TRA2B | interactor | 20 | 0.463 | 35.959 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Transformer (PF06495, IPR010519): Fruit fly transformer protein |
133 |
TRUB2 | interactor | 5 | 0.833 | 0.500 | TruB_N (PF01509, IPR002501): TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 (PF16198, IPR032819): tRNA pseudouridylate synthase B C-terminal domain |
134 |
U2AF2 | protein found in more fusions | 48 | 0.499 | 114.099 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Transformer (PF06495, IPR010519): Fruit fly transformer protein |
135 |
USP45 | interactor | 5 | 0.400 | 1.497 | HNH (PF01844, IPR002711): HNH endonuclease UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase zf-UBP (PF02148, IPR001607, SM00290): Zn-finger in ubiquitin-hydrolases and other protein LELP1 (PF15042, IPR026076): Late cornified envelope-like proline-rich protein 1 |
136 |
VCAM1 | interactor | 28 | 0.484 | 41.513 | C2-set (PF05790, IPR008424): Immunoglobulin C2-set domain I-set (PF07679, IPR013098): Immunoglobulin I-set domain ig (PF00047, IPR013151, SM00409): Immunoglobulin domain V-set (PF07686, IPR013106): Immunoglobulin V-set domain Ig_3 (PF13927): Immunoglobulin domain |
137 |
WWOX | suppressor | 19 | 0.556 | 12.395 | adh_short (PF00106, IPR002198): short chain dehydrogenase WW (PF00397, IPR001202, SM00456): WW domain |
138 |
XRN1 | interactor | 6 | 0.733 | 0.449 | XRN_N (PF03159, IPR004859): XRN 5'-3' exonuclease N-terminus |
139 |
YARS2 | interactor | 5 | 0.800 | 1.167 | S4 (PF01479, IPR002942, SM00363): S4 domain tRNA-synt_1b (PF00579, IPR002305): tRNA synthetases class I (W and Y) |
140 |
YTHDC1 | interactor | 12 | 0.576 | 11.266 | DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777) Merozoite_SPAM (PF07133, IPR010784): Merozoite surface protein (SPAM) Prothymosin (PF03247, IPR004931): Prothymosin/parathymosin family YTH (PF04146, IPR007275): YT521-B-like domain PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term TFB6 (PF17110, IPR031349): Subunit 11 of the general transcription factor TFIIH |
141 |
ZC3H18 | interactor | 19 | 0.433 | 26.398 | FSAP_sig_propep (PF03032, IPR004275): Frog skin active peptide family signal and propeptide Vfa1 (PF08432, IPR013640): AAA-ATPase Vps4-associated protein 1 DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777) Peptidase_S49_N (PF08496, IPR013703): Peptidase family S49 N-terminal Miga (PF10265, IPR019392): Mitoguardin DUF3729 (PF12526, IPR022202): Protein of unknown function (DUF3729) PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term PBP1_TM (PF14812, IPR032730): Transmembrane domain of transglycosylase PBP1 at N-terminal LRR19-TM (PF15176): Leucine-rich repeat family 19 TM domain |
142 |
ZNF490 | interactor | 1 | 0 | 0 | KRAB (PF01352, IPR001909, SM00349): KRAB box TF_Zn_Ribbon (PF08271, IPR013137): TFIIB zinc-binding zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_4 (PF13894): C2H2-type zinc finger zf-C2H2_6 (PF13912, IPR007087): C2H2-type zinc finger |