1 |
NUP98 | parental protein | 66 | 0.129 | 3772.354 | Nucleoporin2 (PF04096, IPR007230): Nucleoporin autopeptidase Nup96 (PF12110, IPR021967): Nuclear protein 96 ANAPC3 (PF12895): Anaphase-promoting complex, cyclosome, subunit 3 Nucleoporin_FG (PF13634, IPR025574): Nucleoporin FG repeat region Keratin_2_head (PF16208, IPR032444): Keratin type II head |
2 |
RAP1GDS1 | parental protein | 61 | 0.092 | 4994.521 | Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat WAPL (PF07814, IPR022771): Wings apart-like protein regulation of heterochromatin Vps39_1 (PF10366, IPR019452): Vacuolar sorting protein 39 domain 1 V-ATPase_H_C (PF11698, IPR011987): V-ATPase subunit H HEAT_2 (PF13646): HEAT repeats Nitr_red_bet_C (PF14711, IPR029263): Respiratory nitrate reductase beta C-terminal SIL1 (PF16782, IPR031884): Nucleotide exchange factor SIL1 |
3 |
ABHD14A | interactor | 8 | 0.714 | 3.022 | Abhydrolase_1 (PF00561, IPR000073): alpha/beta hydrolase fold Abhydrolase_6 (PF12697, IPR000073): Alpha/beta hydrolase family |
4 |
APBB2 | interactor | 2 | 1.000 | 0 | PID (PF00640, IPR006020, SM00462): Phosphotyrosine interaction domain (PTB/PID) WW (PF00397, IPR001202, SM00456): WW domain |
5 |
APC | suppressor | 13 | 0.273 | 120.406 | APC_15aa (PF05972, IPR009240): APC 15 residue motif APC_basic (PF05956, IPR009234): APC basic domain APC_r (PF05923): APC repeat Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972) EB1_binding (PF05937, IPR009232): EB-1 Binding Domain FYDLN_acid (PF09538, IPR012644): Protein of unknown function (FYDLN_acid) SAMP (PF05924, IPR009224): SAMP Motif Suppressor_APC (PF11414, IPR026831): Adenomatous polyposis coli tumour suppressor protein AIF_C (PF14721, IPR029324): Apoptosis-inducing factor, mitochondrion-associated, C-term SAS4 (PF15460, IPR029184): Something about silencing, SAS, complex subunit 4 Arm_APC_u3 (PF16629): Armadillo-associated region on APC APC_u5 (PF16630): Unstructured region on APC between 1st and 2nd catenin-bdg motifs APC_u9 (PF16633): Unstructured region on APC between 1st two creatine-rich regions APC_u13 (PF16634): Unstructured region on APC between APC_crr and SAMP APC_u14 (PF16635): Unstructured region on APC between SAMP and APC_crr APC_u15 (PF16636): Unstructured region on APC between APC_crr regions 5 and 6 APC_N_CC (PF16689, IPR032038): Coiled-coil N-terminus of APC, dimerisation domain |
6 |
ARFGEF2 | interactor | 4 | 0.667 | 1.167 | DUF1539 (PF07560, IPR011436): Domain of Unknown Function (DUF1539) DUF1981 (PF09324, IPR015403): Domain of unknown function (DUF1981) Sec7 (PF01369, IPR000904, SM00222): Sec7 domain Sec7_N (PF12783, IPR032691): Guanine nucleotide exchange factor in Golgi transport N-terminal DCB (PF16213, IPR032629): Dimerisation and cyclophilin-binding domain of Mon2 |
7 |
ASNS | oncoprotein | 14 | 0.484 | 41.986 | Asn_synthase (PF00733, IPR001962): Asparagine synthase GATase_7 (PF13537, IPR000583): Glutamine amidotransferase domain |
8 |
B9D2 | interactor | 9 | 0.778 | 3.407 | B9-C2 (PF07162, IPR010796): Ciliary basal body-associated, B9 protein |
9 |
BAIAP2 | interactor | 7 | 0.333 | 14.176 | IMD (PF08397, IPR013606): IRSp53/MIM homology domain SH3_9 (PF14604, IPR001452): Variant SH3 domain |
10 |
C2orf48 | interactor | 1 | 0 | 0 | NA |
11 |
CAPN1 | interactor | 8 | 0.571 | 73.697 | Calpain_III (PF01067, IPR022682, SM00720): Calpain large subunit, domain III Peptidase_C2 (PF00648, IPR001300, SM00230): Calpain family cysteine protease EF-hand_6 (PF13405, IPR002048): EF-hand domain EF-hand_8 (PF13833, IPR002048): EF-hand domain pair |
12 |
CDC37 | protein found in more fusions | 15 | 0.341 | 95.392 | CDC37_C (PF08564, IPR013873, SM01069): Cdc37 C terminal domain CDC37_M (PF08565, IPR013874, SM01070): Cdc37 Hsp90 binding domain CDC37_N (PF03234, IPR013855, SM01071): Cdc37 N terminal kinase binding Rho_Binding (PF08912, IPR015008): Rho Binding TMF_DNA_bd (PF12329, IPR022092): TATA element modulatory factor 1 DNA binding |
13 |
CDC42 | oncoprotein | 8 | 0.190 | 88.456 | Ras (PF00071, IPR001806, SM00173): Ras family |
14 |
CDC73 | suppressor | 8 | 0.429 | 37.142 | CDC73_C (PF05179, IPR007852): RNA pol II accessory factor, Cdc73 family, C-terminal CDC73_N (PF16050, IPR032041): Paf1 complex subunit CDC73 N-terminal |
15 |
CDK2 | suppressor | 24 | 0.296 | 300.834 | Kdo (PF06293, IPR010440): Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase (PF00069, IPR000719): Protein kinase domain |
16 |
CHMP4B | interactor | 3 | 1.000 | 0 | Snf7 (PF03357, IPR005024): Snf7 |
17 |
CLEC11A | interactor | 1 | 0 | 0 | ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16) HBS1_N (PF08938, IPR015033): HBS1 N-terminus Lectin_C (PF00059, IPR001304, SM00034): Lectin C-type domain |
18 |
COMTD1 | interactor | 4 | 0.333 | 11.003 | FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 |
19 |
CREBBP | suppressor | 11 | 0.467 | 54.292 | Creb_binding (PF09030, IPR014744): Creb binding DUF902 (PF06001, IPR010303): Domain of Unknown Function (DUF902) Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region KIX (PF02172, IPR003101): KIX domain MAS20 (PF02064, IPR002056): MAS20 protein import receptor TPX2 (PF06886, IPR027329): Targeting protein for Xklp2 (TPX2) zf-TAZ (PF02135, IPR000197, SM00551): TAZ zinc finger ANAPC_CDC26 (PF10471, IPR018860): Anaphase-promoting complex APC subunit CDC26 HAT_KAT11 (PF08214, IPR013178): Histone acetylation protein Bromodomain (PF00439, IPR001487, SM00297): Bromodomain ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type DUF3729 (PF12526, IPR022202): Protein of unknown function (DUF3729) DUF4834 (PF16118, IPR032272): Domain of unknown function (DUF4834) |
20 |
CSNK2A1 | oncoprotein | 13 | 0.348 | 40.790 | Pkinase (PF00069, IPR000719): Protein kinase domain |
21 |
CTNNB1 | oncoprotein | 20 | 0.253 | 185.215 | Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat Atx10homo_assoc (PF09759, IPR019156): Spinocerebellar ataxia type 10 protein domain DUF3361 (PF11841, IPR024574): Domain of unknown function (DUF3361) HEAT_EZ (PF13513): HEAT-like repeat |
22 |
CUL7 | protein found in more fusions | 26 | 0.267 | 279.632 | ANAPC10 (PF03256, IPR004939): Anaphase-promoting complex, subunit 10 (APC10) Cullin (PF00888, IPR001373, SM00182): Cullin family DUF1918 (PF08940, IPR015035): Domain of unknown function (DUF1918) Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain Cul7 (PF11515, IPR021097): Mouse development and cellular proliferation protein Cullin-7 |
23 |
DCPS | interactor | 14 | 0.516 | 34.708 | DcpS (PF05652, IPR008594): Scavenger mRNA decapping enzyme (DcpS) N-terminal DcpS_C (PF11969): Scavenger mRNA decapping enzyme C-term binding |
24 |
DIRAS3 | suppressor | 4 | 0.333 | 23.244 | ArgK (PF03308, IPR005129): ArgK protein Ras (PF00071, IPR001806, SM00173): Ras family VirE (PF05272, IPR007936): Virulence-associated protein E |
25 |
DOC2A | interactor | 1 | 0 | 0 | C2 (PF00168, IPR000008, SM00239): C2 domain |
26 |
ECHS1 | protein found in more fusions | 16 | 0.448 | 90.330 | ECH_1 (PF00378, IPR001753): Enoyl-CoA hydratase/isomerase |
27 |
ECT2 | suppressor | 4 | 0.500 | 17.376 | BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain PTCB-BRCT (PF12738, IPR001357): twin BRCT domain PGBA_C (PF15437, IPR032737): Plasminogen-binding protein pgbA C-terminal |
28 |
EED | suppressor | 21 | 0.216 | 226.492 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160 ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain |
29 |
EGFR | oncoprotein | 23 | 0.186 | 503.403 | Furin-like (PF00757, IPR006211): Furin-like cysteine rich region Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase Recep_L_domain (PF01030, IPR000494): Receptor L domain GAPT (PF11770, IPR021082): GRB2-binding adapter (GAPT) GF_recep_IV (PF14843, IPR032778): Growth factor receptor domain IV |
30 |
EP300 | oncoprotein | 14 | 0.359 | 72.726 | Creb_binding (PF09030, IPR014744): Creb binding DUF902 (PF06001, IPR010303): Domain of Unknown Function (DUF902) Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region KIX (PF02172, IPR003101): KIX domain RR_TM4-6 (PF06459, IPR009460): Ryanodine Receptor TM 4-6 TPX2 (PF06886, IPR027329): Targeting protein for Xklp2 (TPX2) zf-TAZ (PF02135, IPR000197, SM00551): TAZ zinc finger HAT_KAT11 (PF08214, IPR013178): Histone acetylation protein Bromodomain (PF00439, IPR001487, SM00297): Bromodomain ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type |
31 |
FAF1 | protein found in more fusions | 9 | 0.357 | 27.430 | UBX (PF00789, IPR001012, SM00166): UBX domain ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family AAA_11 (PF13086): AAA domain UBA_4 (PF14555): UBA-like domain |
32 |
FBXO6 | interactor | 12 | 0.379 | 45.250 | FBA (PF04300, IPR007397): F-box associated region F-box-like (PF12937, IPR001810): F-box-like |
33 |
FOXI2 | interactor | 4 | 1.000 | 0 | Forkhead (PF00250, IPR001766, SM00339): Forkhead domain |
34 |
FOXL1 | oncoprotein | 4 | 0.500 | 4.408 | Forkhead (PF00250, IPR001766, SM00339): Forkhead domain |
35 |
FOXQ1 | interactor | 7 | 0.476 | 13.849 | Forkhead (PF00250, IPR001766, SM00339): Forkhead domain |
36 |
GAPDH | oncoprotein | 19 | 0.281 | 237.154 | Gp_dh_C (PF02800, IPR020829): Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N (PF00044, IPR020828, SM00846): Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain OstA (PF03968, IPR005653): OstA-like protein |
37 |
GINS3 | interactor | 12 | 0.636 | 12.303 | Sld5 (PF05916, IPR021151): GINS complex protein |
38 |
GMDS | protein found in more fusions | 5 | 0.500 | 84.369 | GDP_Man_Dehyd (PF16363, IPR016040): GDP-mannose 4,6 dehydratase |
39 |
GNAI1 | oncoprotein | 1 | 0 | 0 | G-alpha (PF00503, IPR001019, SM00275): G-protein alpha subunit |
40 |
GNAZ | interactor | 2 | 0 | 0 | G-alpha (PF00503, IPR001019, SM00275): G-protein alpha subunit |
41 |
GSS | protein found in more fusions | 15 | 0.495 | 24.029 | GSH_synth_ATP (PF03917, IPR005615): Eukaryotic glutathione synthase, ATP binding domain |
42 |
GTF2H5 | interactor | 3 | 0.333 | 40.309 | Tfb5 (PF06331, IPR009400): Transcription factor TFIIH complex subunit Tfb5 |
43 |
HDAC1 | suppressor | 15 | 0.286 | 88.973 | FSAP_sig_propep (PF03032, IPR004275): Frog skin active peptide family signal and propeptide Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain |
44 |
HDAC11 | interactor | 4 | 0.833 | 0.125 | Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain |
45 |
HDAC7 | protein found in more fusions | 9 | 0.321 | 45.443 | Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain PRIMA1 (PF16101): Proline-rich membrane anchor 1 CBP_BcsO (PF17037, IPR031484): Cellulose biosynthesis protein BcsO |
46 |
HDAC8 | interactor | 1 | 0 | 0 | DNase-RNase (PF02577, IPR003729): Bifunctional nuclease Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain |
47 |
HNRNPUL1 | protein found in more fusions | 11 | 0.467 | 17.296 | Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator Rox3 (PF08633, IPR013942): Rox3 mediator complex subunit SAP (PF02037, IPR003034, SM00513): SAP domain SPRY (PF00622, IPR003877, SM00449): SPRY domain AAA_33 (PF13671): AAA domain PRIMA1 (PF16101): Proline-rich membrane anchor 1 |
48 |
HRAS | oncoprotein | 4 | 0.167 | 29.215 | Ras (PF00071, IPR001806, SM00173): Ras family |
49 |
HSPA1L | interactor | 4 | 0.667 | 0.827 | HSP70 (PF00012, IPR013126): Hsp70 protein |
50 |
HSPA5 | oncoprotein | 23 | 0.242 | 381.578 | HSP70 (PF00012, IPR013126): Hsp70 protein |
51 |
HSPA9 | oncoprotein | 20 | 0.300 | 203.912 | HSP70 (PF00012, IPR013126): Hsp70 protein |
52 |
HSPB9 | interactor | 1 | 0 | 0 | HSP20 (PF00011, IPR002068): Hsp20/alpha crystallin family |
53 |
IFI16 | suppressor | 19 | 0.409 | 119.083 | HIN (PF02760, IPR004021): HIN-200/IF120x domain PYRIN (PF02758, IPR004020): PAAD/DAPIN/Pyrin domain Mitofilin (PF09731, IPR019133): Mitochondrial inner membrane protein |
54 |
KIFAP3 | interactor | 4 | 0.333 | 37.203 | KAP (PF05804): Kinesin-associated protein (KAP) |
55 |
KPNB1 | protein found in more fusions | 32 | 0.297 | 484.126 | Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat HEAT (PF02985, IPR000357): HEAT repeat IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain V-ATPase_H_C (PF11698, IPR011987): V-ATPase subunit H CLASP_N (PF12348, IPR024395): CLASP N terminal Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1 HEAT_EZ (PF13513): HEAT-like repeat |
56 |
KRAS | oncoprotein | 11 | 0.289 | 411.452 | Ras (PF00071, IPR001806, SM00173): Ras family |
57 |
LMNA | protein found in more fusions | 18 | 0.426 | 41.753 | Filament (PF00038, IPR001664): Intermediate filament protein LTD (PF00932, IPR001322): Lamin Tail Domain Uso1_p115_C (PF04871, IPR006955): Uso1 / p115 like vesicle tethering protein, C terminal region DUF3450 (PF11932, IPR016866): Protein of unknown function (DUF3450) DUF4407 (PF14362, IPR025519): Domain of unknown function (DUF4407) |
58 |
MAPK8 | oncoprotein | 10 | 0.250 | 167.855 | DUF530 (PF04409, IPR007503): Protein of unknown function (DUF530) Pkinase (PF00069, IPR000719): Protein kinase domain |
59 |
MBIP | interactor | 2 | 0 | 0 | DUF1192 (PF06698, IPR009579): Protein of unknown function (DUF1192) |
60 |
MOB1A | suppressor | 1 | 0 | 0 | Mob1_phocein (PF03637, IPR005301): Mob1/phocein family |
61 |
MOV10 | interactor | 20 | 0.226 | 246.387 | AAA_12 (PF13087): AAA domain AAA_30 (PF13604): AAA domain |
62 |
MSN | oncoprotein | 20 | 0.374 | 146.109 | DUF883 (PF05957, IPR010279): Bacterial protein of unknown function (DUF883) ERM (PF00769, IPR011259): Ezrin/radixin/moesin family FERM_C (PF09380, IPR018980): FERM C-terminal PH-like domain FERM_M (PF00373, IPR019748): FERM central domain FERM_N (PF09379, IPR018979): FERM N-terminal domain |
63 |
NAE1 | interactor | 9 | 0.583 | 20.078 | ThiF (PF00899, IPR000594): ThiF family |
64 |
NCBP2 | interactor | 1 | 0 | 0 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
65 |
NPM1 | suppressor | 20 | 0.404 | 78.727 | Nucleoplasmin (PF03066): Nucleoplasmin SDA1 (PF05285, IPR007949): SDA1 NPM1-C (PF16276, IPR032569): Nucleophosmin C-terminal domain |
66 |
NRAS | oncoprotein | 1 | 0 | 0 | Ras (PF00071, IPR001806, SM00173): Ras family |
67 |
NTRK1 | oncoprotein | 48 | 0.141 | 1715.636 | I-set (PF07679, IPR013098): Immunoglobulin I-set domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase LRR_8 (PF13855, IPR001611): Leucine rich repeat TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain |
68 |
NUDT21 | protein found in more fusions | 10 | 0.389 | 34.542 | NUDIX_2 (PF13869, IPR016706): Nucleotide hydrolase |
69 |
NUMA1 | oncoprotein | 17 | 0.382 | 117.728 | Colicin (PF01024, IPR000293): Colicin pore forming domain Cytadhesin_P30 (PF07271, IPR009896): Cytadhesin P30/P32 DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664) DUF848 (PF05852, IPR008566): Gammaherpesvirus protein of unknown function (DUF848) Lectin_N (PF03954, IPR005640): Hepatic lectin, N-terminal domain Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein Seryl_tRNA_N (PF02403, IPR015866): Seryl-tRNA synthetase N-terminal domain TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein Tup_N (PF08581, IPR013890): Tup N-terminal CENP-F_leu_zip (PF10473, IPR019513): Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Jnk-SapK_ap_N (PF09744, IPR019143): JNK_SAPK-associated protein-1 DUF3450 (PF11932, IPR016866): Protein of unknown function (DUF3450) DUF4200 (PF13863, IPR025252): Domain of unknown function (DUF4200) Muted (PF14942, IPR017243): Organelle biogenesis, Muted-like protein betaPIX_CC (PF16523, IPR032409): betaPIX coiled coil GIT_CC (PF16559, IPR032352): GIT coiled-coil Rho guanine nucleotide exchange factor DUF5082 (PF16888, IPR031681): Domain of unknown function (DUF5082) |
70 |
NUP107 | interactor | 30 | 0.363 | 297.238 | Nup84_Nup100 (PF04121, IPR007252): Nuclear pore protein 84 / 107 |
71 |
NUP133 | oncoprotein | 20 | 0.400 | 127.857 | Nucleoporin_C (PF03177, IPR007187): Non-repetitive/WGA-negative nucleoporin C-terminal |
72 |
NUP153 | protein found in more fusions | 27 | 0.403 | 166.345 | Nup153 (PF08604, IPR013913): Nucleoporin Nup153-like Nup_retrotrp_bd (PF10599, IPR018892): Retro-transposon transporting motif zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others Nucleoporin_FG (PF13634, IPR025574): Nucleoporin FG repeat region |
73 |
NUP160 | interactor | 19 | 0.497 | 95.231 | Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160 |
74 |
NUP35 | interactor | 13 | 0.603 | 25.947 | Nup35_RRM (PF05172, IPR007846): Nup53/35/40-type RNA recognition motif |
75 |
NUP43 | interactor | 12 | 0.788 | 7.024 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat |
76 |
NUP54 | interactor | 13 | 0.513 | 46.477 | Regulator_TrmB (PF11495, IPR021586): Archaeal transcriptional regulator TrmB KRTAP (PF11759, IPR021743): Keratin-associated matrix Nup54 (PF13874, IPR025712): Nucleoporin complex subunit 54 SUIM_assoc (PF16619): Unstructured region C-term to UIM in Ataxin3 |
77 |
NUP58 | interactor | 10 | 0.489 | 46.001 | Nucleoporin_FG2 (PF15967): Nucleoporin FG repeated region |
78 |
NUP85 | interactor | 21 | 0.376 | 206.630 | Nucleopor_Nup85 (PF07575, IPR011502): Nup85 Nucleoporin |
79 |
NUP88 | interactor | 13 | 0.615 | 49.087 | Nup88 (PF10168, IPR019321): Nuclear pore component |
80 |
NXF1 | interactor | 33 | 0.240 | 502.873 | NTF2 (PF02136, IPR002075): Nuclear transport factor 2 (NTF2) domain Tap-RNA_bind (PF09162, IPR015245): Tap, RNA-binding TAP_C (PF03943, IPR005637, SM00804): TAP C-terminal domain LRR_8 (PF13855, IPR001611): Leucine rich repeat |
81 |
OBSL1 | interactor | 29 | 0.283 | 239.045 | BiPBP_C (PF06832, IPR009647): Penicillin-Binding Protein C-terminus Family fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain Herpes_gE (PF02480, IPR003404): Alphaherpesvirus glycoprotein E I-set (PF07679, IPR013098): Immunoglobulin I-set domain V-set (PF07686, IPR013106): Immunoglobulin V-set domain Ig_3 (PF13927): Immunoglobulin domain Ig_4 (PF16680, IPR032052): T-cell surface glycoprotein CD3 delta chain Izumo-Ig (PF16706, IPR032699): Izumo-like Immunoglobulin domain |
82 |
OLA1 | interactor | 7 | 0.524 | 18.982 | Roc (PF08477, IPR013684): Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 (PF01926, IPR006073): 50S ribosome-binding GTPase YchF-GTPase_C (PF06071, IPR013029): Protein of unknown function (DUF933) |
83 |
PAF1 | oncoprotein | 6 | 0.467 | 21.550 | Paf1 (PF03985, IPR007133): Paf1 MIP-T3 (PF10243): Microtubule-binding protein MIP-T3 |
84 |
PAFAH1B2 | oncoprotein | 12 | 0.500 | 25.467 | Lipase_GDSL_2 (PF13472, IPR013830): GDSL-like Lipase/Acylhydrolase family |
85 |
PARP11 | interactor | 3 | 1.000 | 0 | PARP (PF00644, IPR012317): Poly(ADP-ribose) polymerase catalytic domain WWE (PF02825, IPR004170, SM00678): WWE domain |
86 |
PDIA4 | interactor | 16 | 0.467 | 104.191 | Calsequestrin (PF01216, IPR001393): Calsequestrin Thioredoxin (PF00085, IPR013766): Thioredoxin Thioredoxin_6 (PF13848): Thioredoxin-like domain FAM176 (PF14851): FAM176 family |
87 |
PFAS | interactor | 14 | 0.527 | 54.957 | AIRS_C (PF02769, IPR010918): AIR synthase related protein, C-terminal domain GATase_5 (PF13507): CobB/CobQ-like glutamine amidotransferase domain |
88 |
PIM2 | oncoprotein | 1 | 0 | 0 | Pkinase (PF00069, IPR000719): Protein kinase domain |
89 |
PLEKHB1 | oncoprotein | 1 | 0 | 0 | PH (PF00169, IPR001849, SM00233): PH domain Bacteriocin_IIc (PF10439, IPR019493): Bacteriocin class II with double-glycine leader peptide |
90 |
PNKD | interactor | 5 | 0.700 | 1.667 | Lactamase_B (PF00753, IPR001279, SM00849): Metallo-beta-lactamase superfamily HAGH_C (PF16123, IPR032282): Hydroxyacylglutathione hydrolase C-terminus |
91 |
PPP1R2 | interactor | 9 | 0.556 | 74.217 | IPP-2 (PF04979, IPR007062): Protein phosphatase inhibitor 2 (IPP-2) |
92 |
PPP5C | interactor | 14 | 0.374 | 97.552 | Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase PPP5 (PF08321, IPR013235): PPP5 TPR repeat region TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat TPR_17 (PF13431): Tetratricopeptide repeat |
93 |
PTMA | oncoprotein | 12 | 0.394 | 119.748 | Prothymosin (PF03247, IPR004931): Prothymosin/parathymosin family |
94 |
PTTG1 | oncoprotein | 5 | 0.667 | 1.667 | Securin (PF04856, IPR006940): Securin sister-chromatid separation inhibitor |
95 |
PUF60 | protein found in more fusions | 14 | 0.179 | 195.044 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Titin_Z (PF09042, IPR015129): Titin Z TAT_signal (PF10518, IPR019546): TAT (twin-arginine translocation) pathway signal sequence |
96 |
QRICH2 | interactor | 2 | 0 | 4.748 | Baculo_PEP_C (PF04513, IPR007601): Baculovirus polyhedron envelope protein, PEP, C terminus GLTT (PF01744, IPR008164): GLTT repeat (6 copies) Keratin_B2 (PF01500, IPR002494): Keratin, high sulfur B2 protein LPP (PF04728, IPR006817): Lipoprotein leucine-zipper MbeD_MobD (PF04899, IPR006983): MbeD/MobD like Cnn_1N (PF07989, IPR012943): Centrosomin N-terminal motif 1 DUF4795 (PF16043, IPR032013): Domain of unknown function (DUF4795) |
97 |
RAB1B | oncoprotein | 3 | 0.333 | 9.113 | Ras (PF00071, IPR001806, SM00173): Ras family |
98 |
RAB31 | oncoprotein | 1 | 0 | 0 | Ras (PF00071, IPR001806, SM00173): Ras family |
99 |
RAB34 | oncoprotein | 3 | 0.333 | 5.511 | Ras (PF00071, IPR001806, SM00173): Ras family |
100 |
RAC1 | oncoprotein | 6 | 0.400 | 26.830 | Ras (PF00071, IPR001806, SM00173): Ras family |
101 |
RAE1 | interactor | 17 | 0.441 | 50.928 | Exonuc_X-T_C (PF08411, IPR013620): Exonuclease C-terminal WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160 ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain |
102 |
RAP1A | suppressor | 8 | 0.214 | 117.219 | Ras (PF00071, IPR001806, SM00173): Ras family |
103 |
RAPGEF3 | interactor | 3 | 0.333 | 9.702 | DEP (PF00610, IPR000591, SM00049): Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) RasGEF (PF00617, IPR001895, SM00147): RasGEF domain RasGEF_N (PF00618, IPR000651, SM00229): RasGEF N-terminal motif cNMP_binding (PF00027, IPR000595, SM00100): Cyclic nucleotide-binding domain BAT (PF15915, IPR031803): GAF and HTH_10 associated domain |
104 |
RASD2 | interactor | 1 | 0 | 0 | Ras (PF00071, IPR001806, SM00173): Ras family |
105 |
RASL10A | suppressor | 2 | 1.000 | 0 | Ras (PF00071, IPR001806, SM00173): Ras family |
106 |
RHOA | suppressor | 8 | 0.286 | 53.448 | Ras (PF00071, IPR001806, SM00173): Ras family |
107 |
RNF166 | interactor | 6 | 0.467 | 79.794 | zf-Di19 (PF05605, IPR008598): Drought induced 19 protein (Di19), zinc-binding zinc-ribbons_6 (PF07191, IPR010807): zinc-ribbons Rad50_zn_hook (PF04423, IPR007517): Rad50 zinc hook motif UIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif zinc_ribbon_2 (PF13240, IPR026870): zinc-ribbon domain zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger zf-RING_4 (PF14570): RING/Ubox like zinc-binding domain |
108 |
SEC13 | interactor | 12 | 0.691 | 24.829 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 (PF16529, IPR032401): WD40 region of Ge1, enhancer of mRNA-decapping protein |
109 |
SEH1L | interactor | 15 | 0.695 | 15.701 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 (PF16529, IPR032401): WD40 region of Ge1, enhancer of mRNA-decapping protein |
110 |
SEPT12 | interactor | 2 | 1.000 | 0 | Septin (PF00735, IPR000038): Septin |
111 |
SEPT6 | oncoprotein | 3 | 0.667 | 5.617 | Septin (PF00735, IPR000038): Septin DUF2959 (PF11172, IPR021342): Protein of unknown function (DUF2959) |
112 |
SIRT7 | interactor | 28 | 0.246 | 365.436 | DUF563 (PF04577, IPR007657): Protein of unknown function (DUF563) SIR2 (PF02146, IPR003000): Sir2 family |
113 |
SNX24 | interactor | 1 | 0 | 0 | PX (PF00787, IPR001683, SM00312): PX domain |
114 |
TATDN1 | interactor | 10 | 0.467 | 52.559 | TatD_DNase (PF01026, IPR001130): TatD related DNase |
115 |
TNPO1 | interactor | 8 | 0.500 | 8.428 | Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat HEAT (PF02985, IPR000357): HEAT repeat IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain DUF3437 (PF11919, IPR021843): Domain of unknown function (DUF3437) MMS19_C (PF12460, IPR024687): RNAPII transcription regulator C-terminal Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region HEAT_EZ (PF13513): HEAT-like repeat HEAT_2 (PF13646): HEAT repeats |
116 |
TNPO2 | interactor | 7 | 0.238 | 47.681 | Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat Dopey_N (PF04118, IPR007249): Dopey, N-terminal IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain DUF2573 (PF10835, IPR020393): Protein of unknown function (DUF2573) DUF3437 (PF11919, IPR021843): Domain of unknown function (DUF3437) MMS19_C (PF12460, IPR024687): RNAPII transcription regulator C-terminal Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region HEAT_EZ (PF13513): HEAT-like repeat HEAT_2 (PF13646): HEAT repeats |
117 |
TPR | oncoprotein | 13 | 0.500 | 74.036 | Baculo_PEP_C (PF04513, IPR007601): Baculovirus polyhedron envelope protein, PEP, C terminus ZapB (PF06005, IPR009252): Cell division protein ZapB Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family IncA (PF04156, IPR007285): IncA protein Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein Seryl_tRNA_N (PF02403, IPR015866): Seryl-tRNA synthetase N-terminal domain TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein Jnk-SapK_ap_N (PF09744, IPR019143): JNK_SAPK-associated protein-1 XhlA (PF10779, IPR019715): Haemolysin XhlA ADIP (PF11559, IPR021622): Afadin- and alpha -actinin-Binding Alanine_zipper (PF11839, IPR021793): Alanine-zipper, major outer membrane lipoprotein DUF3373 (PF11853, IPR021803): Protein of unknown function (DUF3373) DUF4107 (PF13389, IPR025180): Protein of unknown function (DUF4107) JIP_LZII (PF16471, IPR032486): JNK-interacting protein leucine zipper II CREPT (PF16566, IPR032337): Cell-cycle alteration and expression-elevated protein in tumour DUF5082 (PF16888, IPR031681): Domain of unknown function (DUF5082) |
118 |
TSC22D4 | interactor | 2 | 1.000 | 0 | AflR (PF08493, IPR013700): Aflatoxin regulatory protein TSC22 (PF01166, IPR000580): TSC-22/dip/bun family |
119 |
UBE2I | interactor | 21 | 0.247 | 354.050 | UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme |
120 |
UBQLN1 | protein found in more fusions | 10 | 0.222 | 159.599 | Clathrin-link (PF09268, IPR015348): Clathrin, heavy-chain linker UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain XPC-binding (PF09280, IPR015360): XPC-binding domain ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family Fur_reg_FbpB (PF13040, IPR025004): Fur-regulated basic protein B FAM199X (PF15814, IPR029672): Protein family FAM199X |
121 |
UNC45A | interactor | 5 | 0.500 | 34.139 | Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat RIX1 (PF08167, IPR012583): rRNA processing/ribosome biogenesis TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat UNC45-central (PF11701, IPR024660): Myosin-binding striated muscle assembly central TPR_16 (PF13432): Tetratricopeptide repeat HEAT_2 (PF13646): HEAT repeats |
122 |
UNK | interactor | 12 | 0.152 | 123.176 | MbeD_MobD (PF04899, IPR006983): MbeD/MobD like NUDE_C (PF04880, IPR006964): NUDE protein, C-terminal conserved region zf-CCCH (PF00642, IPR000571): Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF3450 (PF11932, IPR016866): Protein of unknown function (DUF3450) zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger) zf-CCCH_2 (PF14608): RNA-binding, Nab2-type zinc finger Torus (PF16131, IPR032297): Torus domain |
123 |
USP14 | interactor | 9 | 0.361 | 49.246 | UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family |
124 |
USP7 | oncoprotein | 11 | 0.333 | 35.461 | MATH (PF00917, IPR002083, SM00061): MATH domain UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase USP7_ICP0_bdg (PF12436, IPR024729): ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 (PF14533, IPR029346): Ubiquitin-specific protease C-terminal |
125 |
VCL | oncoprotein | 20 | 0.444 | 93.443 | Vinculin (PF01044, IPR006077): Vinculin family |
126 |
XPO5 | suppressor | 8 | 0.500 | 17.032 | IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain Xpo1 (PF08389, IPR013598): Exportin 1-like protein |
127 |
YWHAE | oncoprotein | 20 | 0.305 | 237.528 | 14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein |
128 |
ZNF451 | protein found in more fusions | 3 | 0 | 13.033 | zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type EPL1 (PF10513, IPR019542): Enhancer of polycomb-like zf-C2H2_jaz (PF12171, IPR022755): Zinc-finger double-stranded RNA-binding zf-C2H2_2 (PF12756, IPR015880): C2H2 type zinc-finger (2 copies) zf-met (PF12874): Zinc-finger of C2H2 type zf-C2H2_4 (PF13894): C2H2-type zinc finger Cys_rich_KTR (PF14205, IPR025957): Cysteine-rich KTR FOXP-CC (PF16159, IPR032354): FOXP coiled-coil domain |