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Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)291
The number (and %) of the onco-proteins94 (32.30 %)
The number (and %) of the tumor suppressors30 (10.31 %)
Total number of binary PPIs (saturation %)2255 (5.34 %)
The number (and %) of affected PPIs301 (13.35 %)
The number of possible different fusions67
PPI diameter3
PPI radius2
The average degree of PPI14.818
Assortativity coefficient-0.2639
The network average Clustering coefficient0.350
The number (and %) of a zero Clustering coefficients29 (9.97 %)
The number (and %) of a zero Betweenness Centrality30 (10.31 %)

ACTIVE INTERACTORS


List of the fusions

PPI for parental proteins: CFTR,RAN All fusions
Proteins found in more fusions HSP90AA1/GNAI2 (see 1 fusions); NTRK1/TFG (see 1 fusions); U2AF2 (see 2 fusions); COMMD1 (see 1 fusions); COPB1 (see 2 fusions); PSMB3 (see 1 fusions); SLC9A3R1 (see 2 fusions); REPS1 (see 1 fusions); RANGAP1 (see 2 fusions); VPS4A (see 1 fusions); NUP153 (see 2 fusions); LGALS3 (see 2 fusions); PAX6 (see 2 fusions); PRKDC (see 3 fusions); CCDC88A (see 3 fusions); GOPC (see 2 fusions); APC (see 1 fusions); HDAC5 (see 1 fusions); IKBKB (see 2 fusions); NEDD4 (see 1 fusions); SNX9 (see 2 fusions); SUZ12 (see 2 fusions); HSPB1/OBSL1 (see 1 fusions); VCP (see 4 fusions); HSP90AA1 (see 2 fusions); HSP90AB1 (see 1 fusions); A2M (see 2 fusions); SNAP23 (see 1 fusions); PAK4 (see 1 fusions); CLCN3 (see 3 fusions); EZR (see 2 fusions); KMT2A (see 16 fusions); RANBP9 (see 2 fusions); CLINT1 (see 2 fusions); STUB1 (see 1 fusions); HSPB1 (see 4 fusions); PRKCE (see 3 fusions); HSPA8/HSPD1 (see 1 fusions); STAU1 (see 2 fusions); RAN/CFTR (see 1 fusions); CBL (see 1 fusions); CUL7 (see 2 fusions); PPME1 (see 1 fusions); SMARCB1 (see 12 fusions); BCAP31 (see 3 fusions); PSAP (see 6 fusions); CDH1 (see 3 fusions); ACTG1 (see 4 fusions); RACK1/FN1 (see 1 fusions); MYO6 (see 3 fusions); BCR/ABL1 (see 183 fusions); ILK (see 1 fusions); CRY2 (see 3 fusions); PKD1 (see 1 fusions); NR3C1 (see 8 fusions); KPNB1 (see 2 fusions); RYR2 (see 1 fusions); SQSTM1 (see 5 fusions); PDCD6 (see 1 fusions); BAG2 (see 1 fusions); ERBIN (see 4 fusions); RACK1 (see 3 fusions); USP10 (see 1 fusions); CFL1/EED (see 1 fusions); EPS8 (see 1 fusions); NTRK1/TPR (see 1 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 CFTRparental protein1900.03034909.007ABC_membrane (PF00664, IPR001140): ABC transporter transmembrane region
ABC_tran (PF00005, IPR003439): ABC transporter
Roc (PF08477, IPR013684): Ras of Complex, Roc, domain of DAPkinase
SMC_N (PF02463, IPR003395): RecF/RecN/SMC N terminal domain
Rotamase_2 (PF13145, IPR000297): PPIC-type PPIASE domain
CFTR_R (PF14396, IPR025837): Cystic fibrosis TM conductance regulator (CFTR), regulator domain
2 RANparental protein1120.08912362.388Ras (PF00071, IPR001806, SM00173): Ras family
3 A2Mprotein found in more fusions50.5002.974A2M (PF00207, IPR001599): Alpha-2-macroglobulin family
A2M_comp (PF07678, IPR011626): A-macroglobulin complement component
A2M_N (PF01835, IPR002890): MG2 domain
A2M_N_2 (PF07703, IPR011625): Alpha-2-macroglobulin family N-terminal region
A2M_recep (PF07677, IPR009048): A-macroglobulin receptor
MP (PF01107, IPR028919): Viral movement protein (MP)
SVA (PF05326, IPR007990): Seminal vesicle autoantigen (SVA)
Thiol-ester_cl (PF10569, IPR019565): Alpha-macro-globulin thiol-ester bond-forming region
4 ABCC4interactor70.38111.727ABC_membrane (PF00664, IPR001140): ABC transporter transmembrane region
ABC_tran (PF00005, IPR003439): ABC transporter
SMC_N (PF02463, IPR003395): RecF/RecN/SMC N terminal domain
5 ABL1oncoprotein210.284223.666Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
SH2 (PF00017, IPR000980, SM00252): SH2 domain
F_actin_bind (PF08919, IPR015015, SM00808): F-actin binding
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
FRG2 (PF15315, IPR026245): Facioscapulohumeral muscular dystrophy candidate 2
6 ACTG1protein found in more fusions170.250114.032Actin (PF00022, IPR004000, SM00268): Actin
7 ADCY8interactor100DUF1053 (PF06327, IPR009398): Domain of Unknown Function (DUF1053)
Serglycin (PF04360, IPR007455): Serglycin
Guanylate_cyc (PF00211, IPR001054, SM00044): Adenylate and Guanylate cyclase catalytic domain
AC_N (PF16214, IPR032628): Adenylyl cyclase N-terminal extracellular and transmembrane region
8 ADRB2interactor270.083465.0817tm_1 (PF00001, IPR000276): 7 transmembrane receptor (rhodopsin family)
9 AGLinteractor40.5003.945GDE_C (PF06202, IPR010401): Amylo-alpha-1,6-glucosidase
hGDE_N (PF14699, IPR029436): N-terminal domain from the human glycogen debranching enzyme
hDGE_amylase (PF14701, IPR032792): Glucanotransferase of human glycogen debranching enzyme
hGDE_central (PF14702, IPR032788): Central domain of human glycogen debranching enzyme
10 AHSA1interactor160.33395.883Aha1_N (PF09229, IPR015310, SM01000): Activator of Hsp90 ATPase, N-terminal
AHSA1 (PF08327, IPR013538): Activator of Hsp90 ATPase homolog 1-like protein
11 AIFM1oncoprotein150.22974.442Pyr_redox_2 (PF07992, IPR023753): Pyridine nucleotide-disulphide oxidoreductase
AIF_C (PF14721, IPR029324): Apoptosis-inducing factor, mitochondrion-associated, C-term
AIF-MLS (PF14962, IPR032773): Mitochondria Localisation Sequence
12 AKAP6interactor21.0000IPK (PF03770, IPR005522): Inositol polyphosphate kinase
Spectrin (PF00435, IPR002017): Spectrin repeat
13 AMFRoncoprotein260.273242.080CUE (PF02845, IPR003892, SM00546): CUE domain
UbiA (PF01040, IPR000537): UbiA prenyltransferase family
zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain
14 APCsuppressor130.242110.665APC_15aa (PF05972, IPR009240): APC 15 residue motif
APC_basic (PF05956, IPR009234): APC basic domain
APC_r (PF05923): APC repeat
Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972)
EB1_binding (PF05937, IPR009232): EB-1 Binding Domain
FYDLN_acid (PF09538, IPR012644): Protein of unknown function (FYDLN_acid)
SAMP (PF05924, IPR009224): SAMP Motif
Suppressor_APC (PF11414, IPR026831): Adenomatous polyposis coli tumour suppressor protein
AIF_C (PF14721, IPR029324): Apoptosis-inducing factor, mitochondrion-associated, C-term
SAS4 (PF15460, IPR029184): Something about silencing, SAS, complex subunit 4
Arm_APC_u3 (PF16629): Armadillo-associated region on APC
APC_u5 (PF16630): Unstructured region on APC between 1st and 2nd catenin-bdg motifs
APC_u9 (PF16633): Unstructured region on APC between 1st two creatine-rich regions
APC_u13 (PF16634): Unstructured region on APC between APC_crr and SAMP
APC_u14 (PF16635): Unstructured region on APC between SAMP and APC_crr
APC_u15 (PF16636): Unstructured region on APC between APC_crr regions 5 and 6
APC_N_CC (PF16689, IPR032038): Coiled-coil N-terminus of APC, dimerisation domain
15 ARoncoprotein220.190221.827Androgen_recep (PF02166, IPR001103): Androgen receptor
zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains)
Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
16 ASB16interactor60.13333.790Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
Ank_4 (PF13637): Ankyrin repeats (many copies)
SOCS_box (PF07525, IPR001496): SOCS box
17 ASB2interactor80.28637.732Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
Ank_4 (PF13637): Ankyrin repeats (many copies)
Ank_5 (PF13857): Ankyrin repeats (many copies)
SOCS_box (PF07525, IPR001496): SOCS box
18 ATAD3Ainteractor150.21969.391AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA)
DUF3523 (PF12037, IPR021911): Domain of unknown function (DUF3523)
19 ATP2A1interactor100Cation_ATPase_C (PF00689, IPR006068): Cation transporting ATPase, C-terminus
Cation_ATPase_N (PF00690, IPR004014, SM00831): Cation transporter/ATPase, N-terminus
E1-E2_ATPase (PF00122, IPR008250): E1-E2 ATPase
Hydrolase_3 (PF08282, IPR023214): haloacid dehalogenase-like hydrolase
HAD (PF12710): haloacid dehalogenase-like hydrolase
Cation_ATPase (PF13246): Cation transport ATPase (P-type)
20 ATP2A2interactor120.27348.969Cation_ATPase_C (PF00689, IPR006068): Cation transporting ATPase, C-terminus
Cation_ATPase_N (PF00690, IPR004014, SM00831): Cation transporter/ATPase, N-terminus
E1-E2_ATPase (PF00122, IPR008250): E1-E2 ATPase
Hydrolase_3 (PF08282, IPR023214): haloacid dehalogenase-like hydrolase
HAD (PF12710): haloacid dehalogenase-like hydrolase
Cation_ATPase (PF13246): Cation transport ATPase (P-type)
21 ATXN2Linteractor80.21442.368LsmAD (PF06741, IPR009604): LsmAD domain
PAM2 (PF07145, IPR009818): Ataxin-2 C-terminal region
SM-ATX (PF14438, IPR025852): Ataxin 2 SM domain
22 B3GNT9interactor100Fringe (PF02434, IPR003378): Fringe-like
Galactosyl_T (PF01762, IPR002659): Galactosyltransferase
23 BAG1oncoprotein160.325115.377BAG (PF02179, IPR003103, SM00264): BAG domain
Presenilin (PF01080, IPR001108): Presenilin
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
DUF5082 (PF16888, IPR031681): Domain of unknown function (DUF5082)
24 BAG2protein found in more fusions190.288168.226IncA (PF04156, IPR007285): IncA protein
Mnd1 (PF03962, IPR005647): Mnd1 family
ParD_antitoxin (PF03693, IPR022789): Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH
25 BCAP31protein found in more fusions110.267103.555Bap31 (PF05529, IPR008417): B-cell receptor-associated protein 31-like
DUF948 (PF06103, IPR009293): Bacterial protein of unknown function (DUF948)
26 BCAR1oncoprotein40.5004.248Serine_rich (PF08824, IPR014928): Serine rich protein interaction domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
DUF3513 (PF12026, IPR021901): Domain of unknown function (DUF3513)
Caskin1-CID (PF16600): Caskin1 CASK-interaction domain
27 BCRsuppressor120.62128.541Bcr-Abl_Oligo (PF09036, IPR015123): Bcr-Abl oncoprotein oligomerisation domain
C2 (PF00168, IPR000008, SM00239): C2 domain
PH (PF00169, IPR001849, SM00233): PH domain
RhoGAP (PF00620, IPR000198, SM00324): RhoGAP domain
RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain
IQ_SEC7_PH (PF16453, IPR001849): PH domain
28 BIRC5interactor90.5009.942BIR (PF00653, IPR001370, SM00238): Inhibitor of Apoptosis domain
29 CALUinteractor100.28930.670EF-hand_6 (PF13405, IPR002048): EF-hand domain
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
EF-hand_8 (PF13833, IPR002048): EF-hand domain pair
30 CAND1interactor470.213869.970Adaptin_N (PF01602, IPR002553): Adaptin N terminal region
DUF1981 (PF09324, IPR015403): Domain of unknown function (DUF1981)
HEAT (PF02985, IPR000357): HEAT repeat
TIP120 (PF08623, IPR013932): TATA-binding protein interacting (TIP20)
RTP1_C1 (PF10363, IPR019451): Required for nuclear transport of RNA pol II C-terminus 1
DUF3385 (PF11865, IPR024585): Domain of unknown function (DUF3385)
MMS19_C (PF12460, IPR024687): RNAPII transcription regulator C-terminal
Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1
Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region
HEAT_EZ (PF13513): HEAT-like repeat
HEAT_2 (PF13646): HEAT repeats
MMS19_N (PF14500): Dos2-interacting transcription regulator of RNA-Pol-II
31 CANXinteractor240.330127.459Calreticulin (PF00262, IPR001580): Calreticulin family
DUF1510 (PF07423, IPR009988): Protein of unknown function (DUF1510)
TRAP_alpha (PF03896, IPR005595): Translocon-associated protein (TRAP), alpha subunit
32 CBLsuppressor170.308217.743Cbl_N (PF02262, IPR003153): CBL proto-oncogene N-terminal domain 1
Cbl_N2 (PF02761, IPR014741): CBL proto-oncogene N-terminus, EF hand-like domain
Cbl_N3 (PF02762, IPR014742): CBL proto-oncogene N-terminus, SH2-like domain
UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
Prok-RING_4 (PF14447): Prokaryotic RING finger family 4
zf-RING_4 (PF14570): RING/Ubox like zinc-binding domain
33 CCDC51interactor202.112XhlA (PF10779, IPR019715): Haemolysin XhlA
CENP-Q (PF13094, IPR025212): CENP-Q, a CENPA-CAD centromere complex subunit
Helo_like_N (PF17111, IPR031348): Fungal N-terminal domain of STAND proteins
34 CCDC88Aprotein found in more fusions80.28625.973bZIP_1 (PF00170, IPR004827): bZIP transcription factor
ZapB (PF06005, IPR009252): Cell division protein ZapB
DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972)
HOOK (PF05622, IPR008636): HOOK protein
Mod_r (PF07200, IPR009851): Modifier of rudimentary (Mod(r)) protein
BLOC1_2 (PF10046, IPR019269): Biogenesis of lysosome-related organelles complex-1 subunit 2
KxDL (PF10241, IPR019371): Uncharacterized conserved protein
GAS (PF13851, IPR025593): Growth-arrest specific micro-tubule binding
DUF4472 (PF14739, IPR029329): Domain of unknown function (DUF4472)
TolA_bind_tri (PF16331, IPR032519): TolA binding protein trimerisation
APC_N_CC (PF16689, IPR032038): Coiled-coil N-terminus of APC, dimerisation domain
35 CCT3interactor280.249223.348Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
36 CCT4interactor260.283174.779Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
37 CD59interactor203.634UPAR_LY6 (PF00021, IPR001526): u-PAR/Ly-6 domain
FAM163 (PF15069, IPR029379): FAM163 family
38 CDH1suppressor120.23641.991Cadherin_C (PF01049, IPR000233): Cadherin cytoplasmic region
Cadherin_pro (PF08758, IPR014868, SM01055): Cadherin prodomain like
Cadherin (PF00028, IPR002126, SM00112): Cadherin domain
39 CDK2suppressor430.167573.970Kdo (PF06293, IPR010440): Lipopolysaccharide kinase (Kdo/WaaP) family
Pkinase (PF00069, IPR000719): Protein kinase domain
40 CEP126interactor30.3335.809Nop25 (PF09805, IPR019186): Nucleolar protein 12 (25kDa)
K1377 (PF15352, IPR028257): Susceptibility to monomelic amyotrophy
41 CEP170interactor80.250103.886FHA (PF00498, IPR000253, SM00240): FHA domain
DUF4254 (PF14063, IPR025350): Protein of unknown function (DUF4254)
CEP170_C (PF15308, IPR029300): CEP170 C-terminus
42 CEP170P1interactor5011.339NA
43 CFL1protein found in more fusions170.228108.006Cofilin_ADF (PF00241, IPR002108, SM00102): Cofilin/tropomyosin-type actin-binding protein
44 CLCA1interactor100CLCA (PF08434, IPR013642): Calcium-activated chloride channel
45 CLCN3protein found in more fusions70.4009.505CBS (PF00571, IPR000644, SM00116): CBS domain
Voltage_CLC (PF00654, IPR001807): Voltage gated chloride channel
46 CLINT1protein found in more fusions80.42915.582ENTH (PF01417, IPR001026, SM00273): ENTH domain
47 CLTAinteractor130.269147.469Clathrin_lg_ch (PF01086, IPR000996): Clathrin light chain
48 CLTCL1oncoprotein80.21416.911Clathrin-link (PF09268, IPR015348): Clathrin, heavy-chain linker
Clathrin_propel (PF01394, IPR022365): Clathrin propeller repeat
Coatomer_WDAD (PF04053, IPR006692): Coatomer WD associated region
Clathrin (PF00637, IPR000547, SM00299): Region in Clathrin and VPS
Clathrin_H_link (PF13838): Clathrin-H-link
49 COMMD1protein found in more fusions60.5006.397COMMD1_N (PF17221): COMMD1 N-terminal domain
COMM_domain (PF07258): COMM domain
50 COPB1protein found in more fusions150.30886.440Adaptin_N (PF01602, IPR002553): Adaptin N terminal region
Coatamer_beta_C (PF07718, IPR011710): Coatomer beta C-terminal region
Coatomer_b_Cpla (PF14806, IPR029446): Coatomer beta subunit appendage platform
51 CRY2protein found in more fusions230.255143.874DNA_photolyase (PF00875, IPR006050): DNA photolyase
FAD_binding_7 (PF03441, IPR005101): FAD binding domain of DNA photolyase
52 CSE1Loncoprotein270.268322.967CAS_CSE1 (PF03378, IPR005043): CAS/CSE protein, C-terminus
Cse1 (PF08506, IPR013713): Cse1
IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain
Xpo1 (PF08389, IPR013598): Exportin 1-like protein
53 CSTBoncoprotein50.30037.957Cystatin (PF00031, IPR000010, SM00043): Cystatin domain
54 CUL7protein found in more fusions560.138914.236ANAPC10 (PF03256, IPR004939): Anaphase-promoting complex, subunit 10 (APC10)
Cullin (PF00888, IPR001373, SM00182): Cullin family
DUF1918 (PF08940, IPR015035): Domain of unknown function (DUF1918)
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
Cul7 (PF11515, IPR021097): Mouse development and cellular proliferation protein Cullin-7
55 DAB2suppressor60.33310.104PID (PF00640, IPR006020, SM00462): Phosphotyrosine interaction domain (PTB/PID)
zf-C2H2_assoc3 (PF16637): Putative zinc-finger between two C2H2 zinc-fingers on Patz
56 DCLK1interactor30.6670.643DCX (PF03607, IPR003533, SM00537): Doublecortin
Pkinase (PF00069, IPR000719): Protein kinase domain
MSA-2c (PF12238, IPR021060): Merozoite surface antigen 2c
57 DERL1interactor110.40024.518DER1 (PF04511, IPR007599): Der1-like family
58 DIS3interactor50.7007.338RNB (PF00773, SM00955): RNB domain
rve (PF00665, IPR001584): Integrase core domain
PIN_4 (PF13638, IPR002716): PIN domain
Rrp44_CSD1 (PF17216): Rrp44-like cold shock domain
Rrp44_S1 (PF17215): S1 domain
59 DNAJA1interactor220.307161.941DnaJ (PF00226, IPR001623, SM00271): DnaJ domain
DnaJ_C (PF01556, IPR002939): DnaJ C terminal domain
60 DNAJA2interactor170.41946.783DnaJ (PF00226, IPR001623, SM00271): DnaJ domain
DnaJ_C (PF01556, IPR002939): DnaJ C terminal domain
61 DNAJB1suppressor140.41885.620DnaJ (PF00226, IPR001623, SM00271): DnaJ domain
DnaJ_C (PF01556, IPR002939): DnaJ C terminal domain
62 DNAJC5interactor31.0000DnaJ (PF00226, IPR001623, SM00271): DnaJ domain
Baculo_F (PF12259, IPR022048): Baculovirus F protein
63 DTLinteractor21.0000WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
64 EEA1interactor60.4009.741ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16)
C1_4 (PF07975, IPR004595, SM01047): TFIIH C1-like domain
CALCOCO1 (PF07888, IPR012852): Calcium binding and coiled-coil domain (CALCOCO1) like
Filament (PF00038, IPR001664): Intermediate filament protein
FYVE (PF01363, IPR000306, SM00064): FYVE zinc finger
IncA (PF04156, IPR007285): IncA protein
Atg14 (PF10186, IPR018791): Vacuolar sorting 38 and autophagy-related subunit 14
Tropomyosin_1 (PF12718, IPR000533): Tropomyosin like
HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1
65 EEDsuppressor360.217382.141WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
66 EIF3Ioncoprotein100.28930.207ISN1 (PF06437, IPR009453): IMP-specific 5'-nucleotidase
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
Ge1_WD40 (PF16529, IPR032401): WD40 region of Ge1, enhancer of mRNA-decapping protein
67 EIF4A3interactor270.357109.699DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
68 EIF6interactor190.310171.193eIF-6 (PF01912, IPR002769, SM00654): eIF-6 family
69 ELAVL1oncoprotein570.1152083.401RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
70 EMC2interactor30.3335.230TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat
TPR_8 (PF13181, IPR019734): Tetratricopeptide repeat
TPR_9 (PF13371, IPR011990): Tetratricopeptide repeat
TPR_11 (PF13414, IPR011990): TPR repeat
TPR_19 (PF14559): Tetratricopeptide repeat
Alkyl_sulf_dimr (PF14863, IPR029228): Alkyl sulfatase dimerisation
71 EMDinteractor180.206158.133LEM (PF03020, IPR003887, SM00540): LEM domain
SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein
72 EPCAMoncoprotein31.0000Asp_protease (PF09668, IPR019103): Aspartyl protease
DAG1 (PF05454, IPR008465): Dystroglycan (Dystrophin-associated glycoprotein 1)
Thyroglobulin_1 (PF00086, IPR000716, SM00211): Thyroglobulin type-1 repeat
73 EPS8oncoprotein31.0000DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region
Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator
PTB (PF08416, IPR013625): Phosphotyrosine-binding domain
SAM_PNT (PF02198, IPR003118, SM00251): Sterile alpha motif (SAM)/Pointed domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
74 ERBINoncoprotein80.52414.265LRR_1 (PF00560, IPR001611): Leucine Rich Repeat
Neur_chan_memb (PF02932, IPR006029): Neurotransmitter-gated ion-channel transmembrane region
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies)
LRR_8 (PF13855, IPR001611): Leucine rich repeat
75 ERLIN1interactor60.33311.297Ribosomal_L33 (PF00471, IPR001705): Ribosomal protein L33
Band_7 (PF01145, IPR001107, SM00244): SPFH domain / Band 7 family
DUF4346 (PF14251, IPR025595): Domain of unknown function (DUF4346)
76 ERLIN2interactor190.281120.275Band_7 (PF01145, IPR001107, SM00244): SPFH domain / Band 7 family
DUF4346 (PF14251, IPR025595): Domain of unknown function (DUF4346)
77 ESR1suppressor500.138993.468Oest_recep (PF02159, IPR001292): Oestrogen receptor
zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains)
Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
ESR1_C (PF12743, IPR024736): Oestrogen-type nuclear receptor final C-terminal
78 ESYT1interactor90.19431.511C2 (PF00168, IPR000008, SM00239): C2 domain
SMP_LBD (PF17047, IPR031468): Synaptotagmin-like mitochondrial-lipid-binding domain
79 EXOSC2interactor60.6004.895EXOSC1 (PF10447, IPR019495): Exosome component EXOSC1/CSL4
ECR1_N (PF14382, IPR025721): Exosome complex exonuclease RRP4 N-terminal region
KH_6 (PF15985, IPR004088): KH domain
80 EZRprotein found in more fusions180.235117.759DUF106 (PF01956, IPR002809): Integral membrane protein DUF106
ERM (PF00769, IPR011259): Ezrin/radixin/moesin family
FERM_C (PF09380, IPR018980): FERM C-terminal PH-like domain
FERM_M (PF00373, IPR019748): FERM central domain
FERM_N (PF09379, IPR018979): FERM N-terminal domain
81 FAM120Ainteractor60.33311.190TPR_15 (PF13429): Tetratricopeptide repeat
82 FARSAinteractor50.10029.491tRNA-synt_2d (PF01409, IPR002319): tRNA synthetases class II core domain (F)
MarR_2 (PF12802): MarR family
83 FLOT2interactor90.25032.094YjbH (PF06082, IPR010344): Exopolysaccharide biosynthesis protein YbjH
Band_7 (PF01145, IPR001107, SM00244): SPFH domain / Band 7 family
Flot (PF15975, IPR031905): Flotillin
84 FN1oncoprotein570.1291226.080fn1 (PF00039, IPR000083, SM00058): Fibronectin type I domain
fn2 (PF00040, IPR000562, SM00059): Fibronectin type II domain
fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369)
85 FUSsuppressor310.314317.919Herpes_PAP (PF03325, IPR004997): Herpesvirus polymerase accessory protein
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
SVS_QK (PF10578, IPR018942): Seminal vesicle protein repeat
zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others
Limkain-b1 (PF11608, IPR024582): Limkain b1
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
Keratin_2_head (PF16208, IPR032444): Keratin type II head
86 GNA11oncoprotein30.3332.901G-alpha (PF00503, IPR001019, SM00275): G-protein alpha subunit
87 GNAI2oncoprotein90.27849.510G-alpha (PF00503, IPR001019, SM00275): G-protein alpha subunit
88 GOPConcoprotein70.20042.302DUF903 (PF06004, IPR010305): Bacterial protein of unknown function (DUF903)
HALZ (PF02183, IPR003106, SM00340): Homeobox associated leucine zipper
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
bZIP_2 (PF07716, IPR004827, SM00338): Basic region leucine zipper
DUF3209 (PF11483, IPR021577): Protein of unknown function (DUF3209)
89 GRNoncoprotein70.23818.121Granulin (PF00396, IPR000118, SM00277): Granulin
Lustrin_cystein (PF14625, IPR028150): Lustrin, cysteine-rich repeated domain
90 H2AFYinteractor110.45511.733DUF1764 (PF08576, IPR013885): Eukaryotic protein of unknown function (DUF1764)
Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
Macro (PF01661, IPR002589, SM00506): Macro domain
Histone_H2A_C (PF16211, IPR032454): C-terminus of histone H2A
91 HACD3interactor90.38920.022PTPLA (PF04387, IPR007482): Protein tyrosine phosphatase-like protein, PTPLA
92 HAX1interactor120.242115.954Mlf1IP (PF10248, IPR019376): Myelodysplasia-myeloid leukemia factor 1-interacting protein
93 HDAC5protein found in more fusions410.185359.455Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
NOA36 (PF06524, IPR010531): NOA36 protein
Activator_LAG-3 (PF11498, IPR021587): Transcriptional activator LAG-3
HDAC4_Gln (PF12203, IPR024643): Glutamine rich N terminal domain of histone deacetylase 4
94 HDAC6oncoprotein300.256338.929Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
PSGP (PF07276, IPR009900): Apopolysialoglycoprotein (PSGP)
zf-UBP (PF02148, IPR001607, SM00290): Zn-finger in ubiquitin-hydrolases and other protein
95 HDGFinteractor160.29266.687PWWP (PF00855, IPR000313, SM00293): PWWP domain
96 HERC5interactor60.6002.558Peptidase_S51 (PF03575, IPR005320): Peptidase family S51
RCC1 (PF00415, IPR000408): Regulator of chromosome condensation (RCC1) repeat
HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
RCC1_2 (PF13540): Regulator of chromosome condensation (RCC1) repeat
97 HIST1H3Einteractor90.30641.400Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
98 HSP90AA1oncoprotein600.2011328.947HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
HSP90 (PF00183, IPR001404): Hsp90 protein
99 HSP90AB1oncoprotein490.259652.525HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
HSP90 (PF00183, IPR001404): Hsp90 protein
100 HSPA1Ainteractor370.270471.043HSP70 (PF00012, IPR013126): Hsp70 protein
101 HSPA1Linteractor160.34258.424HSP70 (PF00012, IPR013126): Hsp70 protein
102 HSPA2interactor80.7501.692HSP70 (PF00012, IPR013126): Hsp70 protein
103 HSPA4interactor390.247622.254Herpes_ICP4_N (PF03584, IPR005206): Herpesvirus ICP4-like protein N-terminal region
HSP70 (PF00012, IPR013126): Hsp70 protein
TP53IP5 (PF15331, IPR029290): Cellular tumour antigen p53-inducible 5
104 HSPA6interactor110.6557.463HSP70 (PF00012, IPR013126): Hsp70 protein
105 HSPA8oncoprotein500.261867.479HSP70 (PF00012, IPR013126): Hsp70 protein
106 HSPB1oncoprotein290.299419.595HSP20 (PF00011, IPR002068): Hsp20/alpha crystallin family
107 HSPB2interactor70.26743.624Crystallin (PF00525, IPR003090): Alpha crystallin A chain, N terminal
HSP20 (PF00011, IPR002068): Hsp20/alpha crystallin family
108 HSPD1suppressor360.263449.271Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
109 HSPH1oncoprotein180.346128.445HSP70 (PF00012, IPR013126): Hsp70 protein
SICA_alpha (PF12887, IPR024290): SICA extracellular alpha domain
110 IKBKBprotein found in more fusions80.38119.144FliT (PF05400, IPR008622): Flagellar protein FliT
Glyco_hydro_65m (PF03632, IPR005195): Glycosyl hydrolase family 65 central catalytic domain
Pkinase (PF00069, IPR000719): Protein kinase domain
SlyX (PF04102, IPR007236): SlyX
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
IKKbetaNEMObind (PF12179, IPR022007): I-kappa-kinase-beta NEMO binding domain
111 IL1RAPL1interactor100TIR (PF01582, IPR000157, SM00255): TIR domain
Ig_2 (PF13895, IPR007110): Immunoglobulin domain
Ig_3 (PF13927): Immunoglobulin domain
112 ILKsuppressor320.105363.449Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
Ank_4 (PF13637): Ankyrin repeats (many copies)
Ank_5 (PF13857): Ankyrin repeats (many copies)
113 IPO11interactor90.52838.026DUF1539 (PF07560, IPR011436): Domain of Unknown Function (DUF1539)
HEAT (PF02985, IPR000357): HEAT repeat
IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain
Xpo1 (PF08389, IPR013598): Exportin 1-like protein
HEAT_2 (PF13646): HEAT repeats
114 IPO13interactor70.47632.646IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain
Xpo1 (PF08389, IPR013598): Exportin 1-like protein
115 IPO5interactor250.353290.269HEAT (PF02985, IPR000357): HEAT repeat
IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain
RTP1_C1 (PF10363, IPR019451): Required for nuclear transport of RNA pol II C-terminus 1
DUF3385 (PF11865, IPR024585): Domain of unknown function (DUF3385)
Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region
HEAT_EZ (PF13513): HEAT-like repeat
AAA_30 (PF13604): AAA domain
HEAT_2 (PF13646): HEAT repeats
PBP1_TM (PF14812, IPR032730): Transmembrane domain of transglycosylase PBP1 at N-terminal
116 IPO7interactor190.39897.560Cse1 (PF08506, IPR013713): Cse1
IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain
RIX1 (PF08167, IPR012583): rRNA processing/ribosome biogenesis
Xpo1 (PF08389, IPR013598): Exportin 1-like protein
DUF2457 (PF10446, IPR018853): Protein of unknown function (DUF2457)
DUF3730 (PF12530, IPR022542): Protein of unknown function (DUF3730)
117 IPO9interactor140.46247.863IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain
RIX1 (PF08167, IPR012583): rRNA processing/ribosome biogenesis
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
Xpo1 (PF08389, IPR013598): Exportin 1-like protein
UNC45-central (PF11701, IPR024660): Myosin-binding striated muscle assembly central
HEAT_EZ (PF13513): HEAT-like repeat
118 ISG15suppressor240.214144.258ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
119 ITGA4interactor420.209414.168FG-GAP (PF01839, IPR013517): FG-GAP repeat
Integrin_alpha (PF00357, IPR018184): Integrin alpha cytoplasmic region
Integrin_alpha2 (PF08441, IPR013649): Integrin alpha
120 JKAMPinteractor40.6675.498DUF766 (PF05571, IPR008485): Protein of unknown function (DUF766)
121 KCNJ1interactor30.6670.420IRK (PF01007, IPR016449): Inward rectifier potassium channel
122 KIF1Cinteractor30.6670.747FHA (PF00498, IPR000253, SM00240): FHA domain
IncA (PF04156, IPR007285): IncA protein
Kinesin (PF00225, IPR001752, SM00129): Kinesin motor domain
Kinesin_assoc (PF16183, IPR032405): Kinesin-associated
123 KIF3Ainteractor40.5008.611Bacillus_HBL (PF05791, IPR008414): Bacillus haemolytic enterotoxin (HBL)
DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664)
Vfa1 (PF08432, IPR013640): AAA-ATPase Vps4-associated protein 1
DUF755 (PF05501, IPR008474): Domain of unknown function (DUF755)
Fez1 (PF06818): Fez1
Kinesin (PF00225, IPR001752, SM00129): Kinesin motor domain
DUF4200 (PF13863, IPR025252): Domain of unknown function (DUF4200)
124 KIF5Binteractor140.242144.934ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16)
Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein
Sec2p (PF06428, IPR009449): GDP/GTP exchange factor Sec2p
Kinesin (PF00225, IPR001752, SM00129): Kinesin motor domain
DUF3584 (PF12128, IPR021979): Protein of unknown function (DUF3584)
HAUS-augmin3 (PF14932, IPR032733): HAUS augmin-like complex subunit 3
DUF4226 (PF10774, IPR019710): Domain of unknown function (DUF4226)
PRKG1_interact (PF15898, IPR031775): cGMP-dependent protein kinase interacting domain
125 KIF5Cinteractor40.5008.611DivIC (PF04977, IPR007060): Septum formation initiator
DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664)
Cnn_1N (PF07989, IPR012943): Centrosomin N-terminal motif 1
Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein
Uso1_p115_C (PF04871, IPR006955): Uso1 / p115 like vesicle tethering protein, C terminal region
Kinesin (PF00225, IPR001752, SM00129): Kinesin motor domain
Hrs_helical (PF12210, IPR024641): Hepatocyte growth factor-regulated tyrosine kinase substrate
DUF4226 (PF10774, IPR019710): Domain of unknown function (DUF4226)
PRKG1_interact (PF15898, IPR031775): cGMP-dependent protein kinase interacting domain
126 KMT2Aoncoprotein110.33369.410AT_hook (PF02178, IPR017956, SM00384): AT hook motif
DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777)
FYRC (PF05965, IPR003889, SM00542): F/Y rich C-terminus
FYRN (PF05964, IPR003888, SM00541): F/Y-rich N-terminus
Peptidase_S49_N (PF08496, IPR013703): Peptidase family S49 N-terminal
PHD (PF00628, IPR019787, SM00249): PHD-finger
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
RNA_pol_Rpc4 (PF05132, IPR007811): RNA polymerase III RPC4
SET (PF00856, IPR001214, SM00317): SET domain
zf-CXXC (PF02008, IPR002857): CXXC zinc finger domain
SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein
Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
zf-HC5HC2H (PF13771): PHD-like zinc-binding domain
DUF4834 (PF16118, IPR032272): Domain of unknown function (DUF4834)
127 KPNA1interactor130.46248.941Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
IBB (PF01749, IPR002652): Importin beta binding domain
Arm_3 (PF16186, IPR032413): Atypical Arm repeat
128 KPNA2interactor210.40568.435Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
IBB (PF01749, IPR002652): Importin beta binding domain
Arm_3 (PF16186, IPR032413): Atypical Arm repeat
129 KPNA5oncoprotein40.8330.200Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
IBB (PF01749, IPR002652): Importin beta binding domain
Arm_3 (PF16186, IPR032413): Atypical Arm repeat
130 KPNA6interactor80.6798.094Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
IBB (PF01749, IPR002652): Importin beta binding domain
Arm_3 (PF16186, IPR032413): Atypical Arm repeat
131 KPNB1protein found in more fusions490.2041461.218Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
HEAT (PF02985, IPR000357): HEAT repeat
IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain
V-ATPase_H_C (PF11698, IPR011987): V-ATPase subunit H
CLASP_N (PF12348, IPR024395): CLASP N terminal
Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1
HEAT_EZ (PF13513): HEAT-like repeat
132 LGALS3oncoprotein110.28951.966Gal-bind_lectin (PF00337, IPR001079, SM00908): Galactoside-binding lectin
133 LGALS4interactor100Gal-bind_lectin (PF00337, IPR001079, SM00908): Galactoside-binding lectin
134 LIN7Cinteractor40.6672.942His_Phos_2 (PF00328, IPR000560): Histidine phosphatase superfamily (branch 2)
L27 (PF02828, IPR014775, SM00569): L27 domain
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
135 LMO7oncoprotein40.3336.572CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
DUF1764 (PF08576, IPR013885): Eukaryotic protein of unknown function (DUF1764)
LIM (PF00412, IPR001781, SM00132): LIM domain
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
DUF2072 (PF09845, IPR018645): Zn-ribbon containing protein
AAA_23 (PF13476): AAA domain
DUF4757 (PF15949, IPR031865): Domain of unknown function (DUF4757)
136 LRRFIP2interactor40.1678.996TACC (PF05010, IPR007707): Transforming acidic coiled-coil-containing protein (TACC)
LRRFIP (PF09738, IPR019139): LRRFIP family
137 MAD2L2interactor40.3333.647HORMA (PF02301, IPR003511): HORMA domain
138 MAGOHinteractor120.51516.030Mago_nashi (PF02792, IPR004023): Mago nashi protein
139 MARCH2interactor40.16712.678Vpu (PF00558, IPR008187): Vpu protein
RINGv (PF12906, IPR011016, SM00744): RING-variant domain
140 MARCKSL1oncoprotein60.200108.816MARCKS (PF02063, IPR002101): MARCKS family
141 MED12oncoprotein50.40027.468Med12 (PF09497, IPR019035): Transcription mediator complex subunit Med12
Peptidase_S15 (PF02129, IPR000383): X-Pro dipeptidyl-peptidase (S15 family)
DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360)
Med19 (PF10278, IPR019403): Mediator of RNA pol II transcription subunit 19
DUF2877 (PF11392, IPR021530): Protein of unknown function (DUF2877)
Med12-PQL (PF12144, IPR021989): Eukaryotic Mediator 12 catenin-binding domain
Med12-LCEWAV (PF12145, IPR021990): Eukaryotic Mediator 12 subunit domain
CYSTM (PF12734, IPR028144): Cysteine-rich TM module stress tolerance
142 MS4A5interactor100CD20 (PF04103, IPR007237): CD20-like family
E1-E2_ATPase (PF00122, IPR008250): E1-E2 ATPase
143 MSL1interactor50.40012.265Herpes_UL6 (PF01763, IPR002660): Herpesvirus UL6 like
KLRAQ (PF10205, IPR019343): Predicted coiled-coil domain-containing protein
PEHE (PF15275, IPR029332): PEHE domain
MSL1_dimer (PF16801, IPR031840): Dimerisation domain of Male-specific-Lethal 1
144 MUC13oncoprotein100SEA (PF01390, IPR000082, SM00200): SEA domain
EGF_MSP1_1 (PF12946, IPR024730): MSP1 EGF domain 1
DUF4064 (PF13273, IPR025273): Protein of unknown function (DUF4064)
145 MYO6protein found in more fusions100.13946.700BUD22 (PF09073, IPR015158): BUD22
IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif
Myosin_N (PF02736, IPR004009): Myosin N-terminal SH3-like domain
Rad9 (PF04139, IPR007268): Rad9
Sec62 (PF03839, IPR004728): Translocation protein Sec62
XhlA (PF10779, IPR019715): Haemolysin XhlA
Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain)
DUF4887 (PF16228, IPR032615): Domain of unknown function (DUF4887)
Myosin-VI_CBD (PF16521, IPR032412): Myosin VI cargo binding domain
146 NEDD4suppressor80.143136.706Rota_NS26 (PF01525, IPR002512): Rotavirus NS26
WW (PF00397, IPR001202, SM00456): WW domain
HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
147 NEK9interactor40.8330.448Pkinase (PF00069, IPR000719): Protein kinase domain
RCC1 (PF00415, IPR000408): Regulator of chromosome condensation (RCC1) repeat
RCC1_2 (PF13540): Regulator of chromosome condensation (RCC1) repeat
148 NHSinteractor21.0000Radial_spoke_3 (PF06098, IPR009290): Radial spoke protein 3
NHS (PF15273, IPR024845): NHS-like
149 NPEPPSinteractor100.33344.649Peptidase_M1 (PF01433, IPR014782): Peptidase family M1
ERAP1_C (PF11838, IPR024571): ERAP1-like C-terminal domain
150 NR3C1protein found in more fusions170.23371.889GCR (PF02155, IPR001409): Glucocorticoid receptor
zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains)
Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
151 NRIP3interactor201.879Asp_protease (PF09668, IPR019103): Aspartyl protease
152 NTRK1oncoprotein1370.0669853.170I-set (PF07679, IPR013098): Immunoglobulin I-set domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
LRR_8 (PF13855, IPR001611): Leucine rich repeat
TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain
153 NUP107interactor210.47664.314Nup84_Nup100 (PF04121, IPR007252): Nuclear pore protein 84 / 107
154 NUP153protein found in more fusions230.390103.143Nup153 (PF08604, IPR013913): Nucleoporin Nup153-like
Nup_retrotrp_bd (PF10599, IPR018892): Retro-transposon transporting motif
zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others
Nucleoporin_FG (PF13634, IPR025574): Nucleoporin FG repeat region
155 NUPR1suppressor50.4003.983Phospho_p8 (PF10195, IPR018792): DNA-binding nuclear phosphoprotein p8
156 NUTF2interactor70.60010.848NTF2 (PF02136, IPR002075): Nuclear transport factor 2 (NTF2) domain
157 NXF1interactor730.0922816.143NTF2 (PF02136, IPR002075): Nuclear transport factor 2 (NTF2) domain
Tap-RNA_bind (PF09162, IPR015245): Tap, RNA-binding
TAP_C (PF03943, IPR005637, SM00804): TAP C-terminal domain
LRR_8 (PF13855, IPR001611): Leucine rich repeat
158 OBSL1protein found in more fusions490.160746.052BiPBP_C (PF06832, IPR009647): Penicillin-Binding Protein C-terminus Family
fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
Herpes_gE (PF02480, IPR003404): Alphaherpesvirus glycoprotein E
I-set (PF07679, IPR013098): Immunoglobulin I-set domain
V-set (PF07686, IPR013106): Immunoglobulin V-set domain
Ig_3 (PF13927): Immunoglobulin domain
Ig_4 (PF16680, IPR032052): T-cell surface glycoprotein CD3 delta chain
Izumo-Ig (PF16706, IPR032699): Izumo-like Immunoglobulin domain
159 P4HA1interactor201.879P4Ha_N (PF08336, IPR013547): Prolyl 4-Hydroxylase alpha-subunit, N-terminal region
TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat
2OG-FeII_Oxy_3 (PF13640, IPR005123): 2OG-Fe(II) oxygenase superfamily
160 PAK4protein found in more fusions51.0000PBD (PF00786, IPR000095, SM00285): P21-Rho-binding domain
Pkinase (PF00069, IPR000719): Protein kinase domain
161 PAN2interactor350.081697.127RNase_T (PF00929, IPR013520): Exonuclease
UCH_1 (PF13423, IPR001394): Ubiquitin carboxyl-terminal hydrolase
WD40_like (PF17005, IPR031544): WD40-like domain
162 PAX6suppressor50.3339.251PAX (PF00292, IPR001523, SM00351): 'Paired box' domain
Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
163 PCDHB8interactor100Cadherin_2 (PF08266, IPR013164): Cadherin-like
Cadherin (PF00028, IPR002126, SM00112): Cadherin domain
Cadherin_3 (PF16184): Cadherin-like
Cadherin_C_2 (PF16492, IPR032455): Cadherin cytoplasmic C-terminal
164 PCMT1interactor120.19765.053PCMT (PF01135, IPR000682): Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)
165 PDCD6oncoprotein110.37837.530EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
166 PDZD3interactor100PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
167 PDZK1interactor60.53310.982PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
DUF4265 (PF14085, IPR025361): Domain of unknown function (DUF4265)
168 PFDN4interactor30.6670.400Prefoldin_2 (PF01920, IPR002777): Prefoldin subunit
169 PKD1suppressor301.749Stress-antifung (PF01657, IPR002902): Salt stress response/antifungal
LRRCT (PF01463, IPR000483, SM00082): Leucine rich repeat C-terminal domain
LRRNT (PF01462, IPR000372, SM00013): Leucine rich repeat N-terminal domain
PKD (PF00801, IPR000601, SM00089): PKD domain
PKD_channel (PF08016, IPR013122): Polycystin cation channel
PLAT (PF01477, IPR001024, SM00308): PLAT/LH2 domain
REJ (PF02010, IPR002859): REJ domain
WSC (PF01822, IPR002889, SM00321): WSC domain
Lectin_C (PF00059, IPR001304, SM00034): Lectin C-type domain
LRR_8 (PF13855, IPR001611): Leucine rich repeat
fn3_3 (PF14686, IPR029413): Polysaccharide lyase family 4, domain II
170 PLEKHA6interactor30.6670.569FliJ (PF02050, IPR012823): Flagellar FliJ protein
PH (PF00169, IPR001849, SM00233): PH domain
Tropomyosin_1 (PF12718, IPR000533): Tropomyosin like
Cep57_CLD_2 (PF14197, IPR025925): Centrosome localisation domain of PPC89
CC2-LZ (PF16516, IPR032419): Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator
171 PPIBinteractor120.33363.654Pro_isomerase (PF00160, IPR002130): Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD
172 PPME1protein found in more fusions110.37827.827Abhydrolase_6 (PF12697, IPR000073): Alpha/beta hydrolase family
173 PPP2CAsuppressor230.344206.629Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase
STPPase_N (PF16891, IPR031675): Serine-threonine protein phosphatase N-terminal domain
174 PPP2R1Aoncoprotein260.317195.502TAF6_C (PF07571, IPR011442): TAF6 C-terminal HEAT repeat domain
HEAT (PF02985, IPR000357): HEAT repeat
HEAT_PBS (PF03130, IPR004155, SM00567): PBS lyase HEAT-like repeat
HEAT_2 (PF13646): HEAT repeats
175 PPP2R1Bsuppressor90.50013.352HEAT (PF02985, IPR000357): HEAT repeat
Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1
Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region
HEAT_2 (PF13646): HEAT repeats
176 PPP2R2Ainteractor120.48548.091WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Y_phosphatase2 (PF03162, IPR004861): Tyrosine phosphatase family
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
177 PPP2R2Binteractor90.41712.972WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
178 PRKAA1suppressor120.48532.472Pkinase (PF00069, IPR000719): Protein kinase domain
AdenylateSensor (PF16579, IPR032270): Adenylate sensor of SNF1-like protein kinase
179 PRKACAinteractor100.28988.729Pkinase (PF00069, IPR000719): Protein kinase domain
180 PRKCEsuppressor80.38147.324C2 (PF00168, IPR000008, SM00239): C2 domain
Pkinase (PF00069, IPR000719): Protein kinase domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain)
181 PRKDCprotein found in more fusions390.212608.574FAT (PF02259, IPR003151): FAT domain
FATC (PF02260, IPR003152): FATC domain
NUC194 (PF08163, IPR012582): NUC194 domain
PI3_PI4_kinase (PF00454, IPR000403, SM00146): Phosphatidylinositol 3- and 4-kinase
182 PSAPoncoprotein60.30023.092SapA (PF02199, IPR003119, SM00162): Saposin A-type domain
SapB_1 (PF05184, IPR007856): Saposin-like type B, region 1
SapB_2 (PF03489, IPR008138): Saposin-like type B, region 2
zf-DBF (PF07535, IPR006572, SM00586): DBF zinc finger
183 PSMA3interactor310.333350.713Proteasome (PF00227, IPR001353): Proteasome subunit
Proteasome_A_N (PF10584, IPR000426, SM00948): Proteasome subunit A N-terminal signature
184 PSMA4interactor220.346209.315Proteasome (PF00227, IPR001353): Proteasome subunit
U79_P34 (PF03064, IPR004138): HSV U79 / HCMV P34
Proteasome_A_N (PF10584, IPR000426, SM00948): Proteasome subunit A N-terminal signature
185 PSMB1interactor150.60076.723Proteasome (PF00227, IPR001353): Proteasome subunit
186 PSMB3protein found in more fusions150.65963.621Proteasome (PF00227, IPR001353): Proteasome subunit
187 PSMB4interactor140.62631.219Integrin_b_cyt (PF08725, IPR014836): Integrin beta cytoplasmic domain
Proteasome (PF00227, IPR001353): Proteasome subunit
188 PSMB5interactor190.421120.418Proteasome (PF00227, IPR001353): Proteasome subunit
189 PSMC4interactor190.427100.547AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA)
NTPase_1 (PF03266, IPR004948): NTPase
CENP-F_leu_zip (PF10473, IPR019513): Leucine-rich repeats of kinetochore protein Cenp-F/LEK1
AAA_16 (PF13191): AAA ATPase domain
190 PSMD11interactor210.329165.438DUF247 (PF03140, IPR004158): Plant protein of unknown function
PCI (PF01399, IPR000717, SM00088): PCI domain
AAA_16 (PF13191): AAA ATPase domain
TPR_12 (PF13424): Tetratricopeptide repeat
191 PSMD2oncoprotein290.234315.533PC_rep (PF01851, IPR002015): Proteasome/cyclosome repeat
THAP (PF05485, IPR006612, SM00980): THAP domain
HEAT_2 (PF13646): HEAT repeats
192 PSME2interactor130.63676.296PA28_alpha (PF02251, IPR003185): Proteasome activator pa28 alpha subunit
PA28_beta (PF02252, IPR003186): Proteasome activator pa28 beta subunit
193 PTGES3interactor160.37172.668CS (PF04969, IPR007052): CS domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
194 PTMAoncoprotein110.30956.465Prothymosin (PF03247, IPR004931): Prothymosin/parathymosin family
195 RAB11Aoncoprotein110.291122.375Ras (PF00071, IPR001806, SM00173): Ras family
196 RAB5Aoncoprotein50.4007.972Ras (PF00071, IPR001806, SM00173): Ras family
197 RACK1suppressor280.205373.848WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
198 RAD21oncoprotein170.243125.357Rad21_Rec8 (PF04824, IPR006909): Conserved region of Rad21 / Rec8 like protein
Rad21_Rec8_N (PF04825, IPR006910): N terminus of Rad21 / Rec8 like protein
FAM176 (PF14851): FAM176 family
WRNPLPNID (PF15017): Putative WW-binding domain and destruction box
199 RANBP1interactor110.509161.790PKI (PF02827, IPR004171): cAMP-dependent protein kinase inhibitor
Ran_BP1 (PF00638, IPR000156, SM00160): RanBP1 domain
200 RANBP10interactor205.875LisH (PF08513, IPR013720, SM00667): LisH
SPRY (PF00622, IPR003877, SM00449): SPRY domain
CLTH (PF10607, IPR024964): CTLH/CRA C-terminal to LisH motif domain
201 RANBP2oncoprotein280.285269.949Pro_isomerase (PF00160, IPR002130): Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD
TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
Ran_BP1 (PF00638, IPR000156, SM00160): RanBP1 domain
zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others
DUF2693 (PF10902, IPR024401): Protein of unknown function (DUF2693)
IR1-M (PF12185, IPR022011): Nup358/RanBP2 E3 ligase domain
Dmrt1 (PF12374, IPR022114): Double-sex mab3 related transcription factor 1
TPR_9 (PF13371, IPR011990): Tetratricopeptide repeat
TPR_11 (PF13414, IPR011990): TPR repeat
TPR_12 (PF13424): Tetratricopeptide repeat
TPR_19 (PF14559): Tetratricopeptide repeat
202 RANBP3oncoprotein80.60712.633Ran_BP1 (PF00638, IPR000156, SM00160): RanBP1 domain
G_path_suppress (PF15991, IPR026094): G-protein pathway suppressor
203 RANBP6interactor70.4769.604HEAT (PF02985, IPR000357): HEAT repeat
IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain
IFRD (PF05004, IPR007701): Interferon-related developmental regulator (IFRD)
RTP1_C1 (PF10363, IPR019451): Required for nuclear transport of RNA pol II C-terminus 1
DUF3385 (PF11865, IPR024585): Domain of unknown function (DUF3385)
Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region
HEAT_2 (PF13646): HEAT repeats
204 RANBP9suppressor120.21862.499Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator
LisH (PF08513, IPR013720, SM00667): LisH
SPRY (PF00622, IPR003877, SM00449): SPRY domain
CLTH (PF10607, IPR024964): CTLH/CRA C-terminal to LisH motif domain
205 RANGAP1protein found in more fusions210.442114.868RanGAP1_C (PF07834, IPR009109): RanGAP1 C-terminal domain
SDA1 (PF05285, IPR007949): SDA1
LRR_6 (PF13516, IPR001611): Leucine Rich repeat
LRR_8 (PF13855, IPR001611): Leucine rich repeat
206 RANGRFinteractor100Mog1 (PF04603, IPR007681): Ran-interacting Mog1 protein
207 RAPGEF3interactor31.0000DEP (PF00610, IPR000591, SM00049): Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP)
RasGEF (PF00617, IPR001895, SM00147): RasGEF domain
RasGEF_N (PF00618, IPR000651, SM00229): RasGEF N-terminal motif
cNMP_binding (PF00027, IPR000595, SM00100): Cyclic nucleotide-binding domain
BAT (PF15915, IPR031803): GAF and HTH_10 associated domain
208 RBM39oncoprotein190.37457.518RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
MIP-T3 (PF10243): Microtubule-binding protein MIP-T3
RBM39linker (PF15519, IPR029123): linker between RRM2 and RRM3 domains in RBM39 protein
209 RCC1interactor250.360167.562RCC1 (PF00415, IPR000408): Regulator of chromosome condensation (RCC1) repeat
RCC1_2 (PF13540): Regulator of chromosome condensation (RCC1) repeat
210 RCN1interactor120.27361.793EF-hand_1 (PF00036, IPR002048, SM00054): EF hand
EF-hand_4 (PF12763, IPR000261): Cytoskeletal-regulatory complex EF hand
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
211 RCN2interactor50.5008.414EF-hand_1 (PF00036, IPR002048, SM00054): EF hand
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
212 REPS1protein found in more fusions40.3337.361Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator
MCLC (PF05934, IPR009231): Mid-1-related chloride channel (MCLC)
DUF3123 (PF11321, IPR021470): Protein of unknown function (DUF3123)
EF-hand_4 (PF12763, IPR000261): Cytoskeletal-regulatory complex EF hand
213 RGPD5interactor40.6670.536GRIP (PF01465, IPR000237, SM00755): GRIP domain
TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
Ran_BP1 (PF00638, IPR000156, SM00160): RanBP1 domain
TPR_9 (PF13371, IPR011990): Tetratricopeptide repeat
TPR_11 (PF13414, IPR011990): TPR repeat
TPR_12 (PF13424): Tetratricopeptide repeat
FlxA (PF14282, IPR025577): FlxA-like protein
TPR_19 (PF14559): Tetratricopeptide repeat
Rab_bind (PF16704, IPR032023): Rab binding domain
214 RHOT1interactor60.4009.697EF_assoc_1 (PF08355, IPR013566): EF hand associated
EF_assoc_2 (PF08356, IPR013567): EF hand associated
Ras (PF00071, IPR001806, SM00173): Ras family
EF-hand_6 (PF13405, IPR002048): EF-hand domain
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
215 RNF185interactor90.39324.184zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
216 RNF2interactor480.111983.010zf-C4_Topoisom (PF01396, IPR013498): Topoisomerase DNA binding C4 zinc finger
zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
RAWUL (PF16207, IPR032443): RAWUL domain RING finger- and WD40-associated ubiquitin-like
217 RNF5interactor90.57111.621zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
218 RPL7interactor230.41160.448Ribosomal_L30 (PF00327, IPR016082): Ribosomal protein L30p/L7e
Ribosomal_L30_N (PF08079, IPR012988): Ribosomal L30 N-terminal domain
219 RYKoncoprotein60.33310.080Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
WIF (PF02019, IPR003306, SM00469): WIF domain
220 RYR2protein found in more fusions60.4008.295Ins145_P3_rec (PF08709, IPR014821): Inositol 1,4,5-trisphosphate/ryanodine receptor
Ion_trans (PF00520, IPR005821): Ion transport protein
MIR (PF02815, IPR016093, SM00472): MIR domain
RIH_assoc (PF08454, IPR013662): RyR and IP3R Homology associated
RR_TM4-6 (PF06459, IPR009460): Ryanodine Receptor TM 4-6
RYDR_ITPR (PF01365, IPR000699): RIH domain
RyR (PF02026, IPR003032): RyR domain
SPRY (PF00622, IPR003877, SM00449): SPRY domain
SRP72 (PF08492, IPR013699): SRP72 RNA-binding domain
EF-hand_8 (PF13833, IPR002048): EF-hand domain pair
YjfB_motility (PF14070, IPR025906): Putative motility protein
221 RYR3interactor21.0000Ins145_P3_rec (PF08709, IPR014821): Inositol 1,4,5-trisphosphate/ryanodine receptor
Ion_trans (PF00520, IPR005821): Ion transport protein
MIR (PF02815, IPR016093, SM00472): MIR domain
RIH_assoc (PF08454, IPR013662): RyR and IP3R Homology associated
RR_TM4-6 (PF06459, IPR009460): Ryanodine Receptor TM 4-6
RYDR_ITPR (PF01365, IPR000699): RIH domain
RyR (PF02026, IPR003032): RyR domain
SPRY (PF00622, IPR003877, SM00449): SPRY domain
EF-hand_1 (PF00036, IPR002048, SM00054): EF hand
EF-hand_8 (PF13833, IPR002048): EF-hand domain pair
222 S100A7oncoprotein50.40022.307S_100 (PF01023, IPR013787): S-100/ICaBP type calcium binding domain
EF-hand_1 (PF00036, IPR002048, SM00054): EF hand
223 S100A9oncoprotein150.297183.344S_100 (PF01023, IPR013787): S-100/ICaBP type calcium binding domain
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
224 SARAFinteractor30.3332.594SARAF (PF06682, IPR009567): SOCE-associated regulatory factor of calcium homoeostasis
225 SEC61A1interactor100.26740.238DUF1430 (PF07242, IPR006541): Protein of unknown function (DUF1430)
SecY (PF00344, IPR002208): SecY translocase
Plug_translocon (PF10559, IPR019561): Plug domain of Sec61p
226 SEC61A2interactor21.0000SecY (PF00344, IPR002208): SecY translocase
Plug_translocon (PF10559, IPR019561): Plug domain of Sec61p
227 SEPT11interactor90.22297.907Septin (PF00735, IPR000038): Septin
DUF3080 (PF11279, IPR021431): Protein of unknown function (DUF3080)
228 SEPT6oncoprotein40.8331.177Septin (PF00735, IPR000038): Septin
DUF2959 (PF11172, IPR021342): Protein of unknown function (DUF2959)
229 SEPT9oncoprotein120.30373.229Septin (PF00735, IPR000038): Septin
DUF3306 (PF11748, IPR021735): Protein of unknown function (DUF3306)
230 SF3B6interactor170.42641.730RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
231 SFXN3interactor60.26714.329Mtc (PF03820, IPR004686): Tricarboxylate carrier
232 SH3BGRL2oncoprotein203.634SH3BGR (PF04908, IPR006993): SH3-binding, glutamic acid-rich protein
233 SIGMAR1interactor202.112ERG2_Sigma1R (PF04622, IPR006716): ERG2 and Sigma1 receptor like protein
234 SIN3Aoncoprotein160.292163.499Sin3_corepress (PF08295, IPR013194, SM00761): Sin3 family co-repressor
PAH (PF02671, IPR003822, SM00309): Paired amphipathic helix repeat
Sin3a_C (PF16879, IPR031693): C-terminal domain of Sin3a protein
235 SKIV2Linteractor21.0000DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
DSHCT (PF08148, IPR012961, SM01142): DSHCT (NUC185) domain
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
DUF3516 (PF12029, IPR021904): Domain of unknown function (DUF3516)
rRNA_proc-arch (PF13234, IPR025696): rRNA-processing arch domain
236 SLC4A7interactor40.5003.683Band_3_cyto (PF07565, IPR013769): Band 3 cytoplasmic domain
HCO3_cotransp (PF00955, IPR011531): HCO3- transporter family
OAD_gamma (PF04277, IPR005899): Oxaloacetate decarboxylase, gamma chain
DUF2628 (PF10947, IPR024399): Protein of unknown function (DUF2628)
FAM176 (PF14851): FAM176 family
DUF4519 (PF15012, IPR027960): Domain of unknown function (DUF4519)
237 SLC9A3R1suppressor160.238178.629EBP50_C (PF09007, IPR015098): EBP50, C-terminal
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
238 SLC9A3R2interactor100.222106.793EBP50_C (PF09007, IPR015098): EBP50, C-terminal
GRASP55_65 (PF04495, IPR024958): GRASP55/65 PDZ-like domain
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
239 SLX1Binteractor70.81021.500GIY-YIG (PF01541, IPR000305, SM00465): GIY-YIG catalytic domain
FANCL_C (PF11793, IPR026850): FANCL C-terminal domain
240 SMARCA2suppressor120.33376.096DUF1168 (PF06658, IPR009548): Protein of unknown function (DUF1168)
DUF1840 (PF08895, IPR014991): Domain of unknown function (DUF1840)
HSA (PF07529, IPR014012, SM00573): HSA
QLQ (PF08880, IPR014978, SM00951): QLQ
SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain
YL1 (PF05764, IPR008895): YL1 nuclear protein
BRK (PF07533, IPR006576, SM00592): BRK domain
DUF2052 (PF09747, IPR018613): Coiled-coil domain containing protein (DUF2052)
EPL1 (PF10513, IPR019542): Enhancer of polycomb-like
Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
SnAC (PF14619, IPR029295): Snf2-ATP coupling, chromatin remodelling complex
WRNPLPNID (PF15017): Putative WW-binding domain and destruction box
241 SMARCB1suppressor120.29151.889SNF5 (PF04855, IPR006939): SNF5 / SMARCB1 / INI1
242 SNAP23protein found in more fusions70.26726.848DivIC (PF04977, IPR007060): Septum formation initiator
DUF16 (PF01519, IPR002862): Protein of unknown function DUF16
SNAP-25 (PF00835, IPR000928): SNAP-25 family
DUF5089 (PF17002, IPR031547): Domain of unknown function (DUF5089)
243 SNUPNinteractor30.6670.091mRNA_cap_enzyme (PF01331, IPR001339): mRNA capping enzyme, catalytic domain
Snurportin1 (PF11538, IPR024721): Snurportin1
244 SNX4interactor100PX (PF00787, IPR001683, SM00312): PX domain
Vps5 (PF09325, IPR015404): Vps5 C terminal like
245 SNX9protein found in more fusions403.423PX (PF00787, IPR001683, SM00312): PX domain
BAR_3_WASP_bdg (PF10456, IPR019497): WASP-binding domain of Sorting nexin protein
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
246 SONinteractor170.52243.653Asp-B-Hydro_N (PF05279, IPR007943): Aspartyl beta-hydroxylase N-terminal region
G-patch (PF01585, IPR000467, SM00443): G-patch domain
tRNA_synt_1c_R2 (PF04557, IPR007638): Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2
Eapp_C (PF10238, IPR019370): E2F-associated phosphoprotein
DND1_DSRM (PF14709): double strand RNA binding domain from DEAD END PROTEIN 1
GREB1 (PF15782, IPR028422): Gene regulated by oestrogen in breast cancer
RSRP (PF17069): Arginine/Serine-Rich protein 1
247 SORL1oncoprotein100fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
Tissue_fac (PF01108, IPR003961): Tissue factor
Ldl_recept_a (PF00057, IPR002172, SM00192): Low-density lipoprotein receptor domain class A
Ldl_recept_b (PF00058, IPR000033, SM00135): Low-density lipoprotein receptor repeat class B
hEGF (PF12661, IPR013032): Human growth factor-like EGF
Sortilin_C (PF15901, IPR031777): Sortilin, neurotensin receptor 3, C-terminal
Sortilin-Vps10 (PF15902, IPR031778): Sortilin, neurotensin receptor 3
Pur_ac_phosph_N (PF16656, IPR015914): Purple acid Phosphatase, N-terminal domain
fn3_2 (PF16893, IPR031669): Fibronectin type III domain
248 SPTLC1interactor30.3336.671Aminotran_1_2 (PF00155, IPR004839): Aminotransferase class I and II
249 SQRDLinteractor100Pyr_redox_2 (PF07992, IPR023753): Pyridine nucleotide-disulphide oxidoreductase
250 SQSTM1oncoprotein160.31480.341PB1 (PF00564, IPR000270, SM00666): PB1 domain
ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type
UBA_5 (PF16577, IPR015940): UBA domain
251 STAU1protein found in more fusions320.245261.851dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif
Staufen_C (PF16482, IPR032478): Staufen C-terminal domain
252 STUB1suppressor290.362190.320U-box (PF04564, IPR003613, SM00504): U-box domain
ANAPC3 (PF12895): Anaphase-promoting complex, cyclosome, subunit 3
TPR_11 (PF13414, IPR011990): TPR repeat
TPR_20 (PF14561): Tetratricopeptide repeat
253 STX1Ainteractor50.5002.820Syntaxin (PF00804, IPR006011, SM00503): Syntaxin
SNARE (PF05739, IPR000727, SM00397): SNARE domain
4HB_MCP_1 (PF12729, IPR024478): Four helix bundle sensory module for signal transduction
254 SUZ12suppressor360.232287.883DUF2070 (PF09843, IPR019204): Predicted membrane protein (DUF2070)
VEFS-Box (PF09733, IPR019135): VEFS-Box of polycomb protein
255 SVILinteractor130.154171.567Gelsolin (PF00626, IPR007123): Gelsolin repeat
VHP (PF02209, IPR003128, SM00153): Villin headpiece domain
DUF4695 (PF15766, IPR031521): Domain of unknown function (DUF4695)
256 TAF6interactor60.80018.618CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
TAF6_C (PF07571, IPR011442): TAF6 C-terminal HEAT repeat domain
Spo0A_C (PF08769, IPR014879): Sporulation initiation factor Spo0A C terminal
TAF (PF02969, IPR004823, SM00803): TATA box binding protein associated factor (TAF)
257 TCEB1oncoprotein110.182158.276Skp1_POZ (PF03931, IPR016073): Skp1 family, tetramerisation domain
258 TCEB2interactor70.381103.095ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
259 TFAP2Asuppressor60.26717.808TF_AP-2 (PF03299, IPR013854): Transcription factor AP-2
CYYR1 (PF10873, IPR022640): Cysteine and tyrosine-rich protein 1
Peptidase_Prp (PF04327): Cysteine protease Prp
260 TFAP4oncoprotein30.6673.062DivIC (PF04977, IPR007060): Septum formation initiator
HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
DUF2407 (PF10302, IPR019413): DUF2407 ubiquitin-like domain
261 TFGoncoprotein110.222143.345ARS2 (PF04959, IPR007042): Arsenite-resistance protein 2
MucBP (PF06458, IPR009459): MucBP domain
PB1 (PF00564, IPR000270, SM00666): PB1 domain
TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
262 THEM6interactor305.9714HBT_2 (PF13279): Thioesterase-like superfamily
263 TIAM1oncoprotein21.0000PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
PH (PF00169, IPR001849, SM00233): PH domain
RBD (PF02196, IPR003116, SM00455): Raf-like Ras-binding domain
RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain
AAA_22 (PF13401, IPR003593): AAA domain
264 TJP3interactor21.0000PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
SH3_2 (PF07653, IPR011511): Variant SH3 domain
Guanylate_kin (PF00625, IPR008145, SM00072): Guanylate kinase
265 TMEM43interactor30.6670.569TMEM43 (PF07787, IPR012430): Transmembrane protein 43
UPF0697 (PF15117, IPR029368): Uncharacterised protein family UPF0697
266 TNPO1interactor150.33375.912Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
HEAT (PF02985, IPR000357): HEAT repeat
IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain
DUF3437 (PF11919, IPR021843): Domain of unknown function (DUF3437)
MMS19_C (PF12460, IPR024687): RNAPII transcription regulator C-terminal
Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1
Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region
HEAT_EZ (PF13513): HEAT-like repeat
HEAT_2 (PF13646): HEAT repeats
267 TNPO2interactor50.8000.717Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
Dopey_N (PF04118, IPR007249): Dopey, N-terminal
IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain
DUF2573 (PF10835, IPR020393): Protein of unknown function (DUF2573)
DUF3437 (PF11919, IPR021843): Domain of unknown function (DUF3437)
MMS19_C (PF12460, IPR024687): RNAPII transcription regulator C-terminal
Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1
Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region
HEAT_EZ (PF13513): HEAT-like repeat
HEAT_2 (PF13646): HEAT repeats
268 TNPO3interactor110.40038.075HEAT (PF02985, IPR000357): HEAT repeat
IFRD (PF05004, IPR007701): Interferon-related developmental regulator (IFRD)
Xpo1 (PF08389, IPR013598): Exportin 1-like protein
269 TPRoncoprotein170.41258.214Baculo_PEP_C (PF04513, IPR007601): Baculovirus polyhedron envelope protein, PEP, C terminus
ZapB (PF06005, IPR009252): Cell division protein ZapB
Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family
IncA (PF04156, IPR007285): IncA protein
Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein
Seryl_tRNA_N (PF02403, IPR015866): Seryl-tRNA synthetase N-terminal domain
TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein
Jnk-SapK_ap_N (PF09744, IPR019143): JNK_SAPK-associated protein-1
XhlA (PF10779, IPR019715): Haemolysin XhlA
ADIP (PF11559, IPR021622): Afadin- and alpha -actinin-Binding
Alanine_zipper (PF11839, IPR021793): Alanine-zipper, major outer membrane lipoprotein
DUF3373 (PF11853, IPR021803): Protein of unknown function (DUF3373)
DUF4107 (PF13389, IPR025180): Protein of unknown function (DUF4107)
JIP_LZII (PF16471, IPR032486): JNK-interacting protein leucine zipper II
CREPT (PF16566, IPR032337): Cell-cycle alteration and expression-elevated protein in tumour
DUF5082 (PF16888, IPR031681): Domain of unknown function (DUF5082)
270 TRA2Binteractor140.47332.644RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
Transformer (PF06495, IPR010519): Fruit fly transformer protein
271 TRIP12interactor60.20050.704Alpha_GJ (PF03229, IPR004913): Alphavirus glycoprotein J
Ndc1_Nup (PF09531, IPR019049): Nucleoporin protein Ndc1-Nup
WWE (PF02825, IPR004170, SM00678): WWE domain
SOG2 (PF10428, IPR019487): RAM signalling pathway protein
HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
UNC45-central (PF11701, IPR024660): Myosin-binding striated muscle assembly central
HEAT_2 (PF13646): HEAT repeats
272 TYK2interactor100.13922.785Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
273 U2AF1oncoprotein160.43394.248DUF1509 (PF07420, IPR010883): Protein of unknown function (DUF1509)
KMP11 (PF03037, IPR004132): Kinetoplastid membrane protein 11
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
zf-CCCH (PF00642, IPR000571): Zinc finger C-x8-C-x5-C-x3-H type (and similar)
274 U2AF2protein found in more fusions440.249527.503RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
Transformer (PF06495, IPR010519): Fruit fly transformer protein
275 UBE2Iinteractor310.221708.924UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
276 UBE3Aoncoprotein120.30952.478HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
PCM1_C (PF15717, IPR031446): Pericentriolar material 1 C terminus
AZUL (PF16558, IPR032353): Amino-terminal Zinc-binding domain of ubiquitin ligase E3A
277 USP10protein found in more fusions60.60010.950PAM2 (PF07145, IPR009818): Ataxin-2 C-terminal region
UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase
YukD (PF08817, IPR024962): WXG100 protein secretion system (Wss), protein YukD
278 USP19interactor110.30966.892CS (PF04969, IPR007052): CS domain
UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase
USP19_linker (PF16602): Linker region of USP19 deubiquitinase
279 USP9Xinteractor120.33365.807DUF1722 (PF08349, IPR013560): Protein of unknown function (DUF1722)
UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase
Utp13 (PF08625, IPR013934): Utp13 specific WD40 associated domain
280 VCAM1interactor440.167461.815C2-set (PF05790, IPR008424): Immunoglobulin C2-set domain
I-set (PF07679, IPR013098): Immunoglobulin I-set domain
ig (PF00047, IPR013151, SM00409): Immunoglobulin domain
V-set (PF07686, IPR013106): Immunoglobulin V-set domain
Ig_3 (PF13927): Immunoglobulin domain
281 VCPprotein found in more fusions540.239899.431AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA)
CDC48_2 (PF02933, IPR004201, SM01072): Cell division protein 48 (CDC48), domain 2
CDC48_N (PF02359, IPR003338, SM01073): Cell division protein 48 (CDC48), N-terminal domain
TniB (PF05621, IPR008868): Bacterial TniB protein
Vps4_C (PF09336, IPR015415): Vps4 C terminal oligomerisation domain
DUF3944 (PF13099, IPR025217): Domain of unknown function (DUF3944)
282 VIPR1interactor1007tm_2 (PF00002, IPR000832): 7 transmembrane receptor (Secretin family)
HRM (PF02793, IPR001879, SM00008): Hormone receptor domain
283 VPS4Aprotein found in more fusions200AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA)
MIT (PF04212, IPR007330, SM00745): MIT (microtubule interacting and transport) domain
TIP49 (PF06068, IPR010339): TIP49 C-terminus
Vps4_C (PF09336, IPR015415): Vps4 C terminal oligomerisation domain
YCII (PF03795, IPR005545): YCII-related domain
284 XPNPEP3interactor302.660AMP_N (PF05195, IPR007865, SM01011): Aminopeptidase P, N-terminal domain
Peptidase_M24 (PF00557, IPR001714): Metallopeptidase family M24
285 XPO1interactor650.1362571.014CRM1_C (PF08767, IPR014877, SM01102): CRM1 C terminal
Hydrolase_3 (PF08282, IPR023214): haloacid dehalogenase-like hydrolase
IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain
Xpo1 (PF08389, IPR013598): Exportin 1-like protein
Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region
286 XPO4interactor50.7004.143CRM1_C (PF08767, IPR014877, SM01102): CRM1 C terminal
287 XPO5suppressor100.31127.982IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain
Xpo1 (PF08389, IPR013598): Exportin 1-like protein
288 XPO6interactor100IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain
Xpo1 (PF08389, IPR013598): Exportin 1-like protein
289 XPO7interactor90.55621.990IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain
Rep_fac_C (PF08542, IPR013748): Replication factor C C-terminal domain
290 XPOTinteractor80.35711.772DUF310 (PF03750, IPR010149): Protein of unknown function (DUF310)
IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain
Xpo1 (PF08389, IPR013598): Exportin 1-like protein
291 XRCC1interactor110.30940.481BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain
SPX (PF03105, IPR004331): SPX domain
XRCC1_N (PF01834, IPR002706): XRCC1 N terminal domain
BRCT_2 (PF16589, IPR001357): BRCT domain, a BRCA1 C-terminus domain

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