Statistic of PPI	Value(s)
The number of interactors (fusion and proteins)	195
The number (and %) of the onco-proteins	47 (24.10 %)
The number (and %) of the tumor suppressors	34 (17.44 %)
Total number of binary PPIs (saturation %)	2269 (12.00 %)
The number (and %) of affected PPIs	195 (8.59 %)
The number of possible different fusions	33
PPI diameter	2
PPI radius	1
The average degree of PPI	22.492
Assortativity coefficient	-0.1431
The network average Clustering coefficient	0.540
The number (and %) of a zero Clustering coefficients	7 (3.59 %)
The number (and %) of a zero Betweenness Centrality	25 (12.82 %)

ACTIVE INTERACTORS

List of the fusions
PPI for parental proteins: RACK1	All fusions : CF619142; AA328791; BE003913;
Proteins found in more fusions	U2AF2 (see 2 fusions); NPM1 (see 1 fusions); CUL1 (see 3 fusions); SLC9A3R1 (see 2 fusions); FYN (see 1 fusions); VHL (see 1 fusions); GAN (see 1 fusions); STAT1 (see 1 fusions); SUZ12 (see 2 fusions); TRAF6 (see 1 fusions); HUWE1 (see 2 fusions); EEF1A1/RPL12 (see 1 fusions); EZH2 (see 1 fusions); PRKCE (see 3 fusions); STAU1 (see 2 fusions); EEF1A1 (see 1 fusions); NTRK1/RPL7A (see 1 fusions); CUL7 (see 2 fusions); CUL3 (see 1 fusions); PDE4D (see 2 fusions); SKI (see 1 fusions); COPS5 (see 1 fusions); RACK1/FN1 (see 1 fusions); SAT1 (see 5 fusions); SREK1 (see 4 fusions); NR3C1 (see 8 fusions); PABPC1 (see 2 fusions); PCBP2 (see 3 fusions); MCM2 (see 1 fusions); RACK1 (see 3 fusions); JAK1 (see 1 fusions); MAP3K7 (see 7 fusions);

List of the fusions

PPI for parental proteins: RACK1

All fusions

: CF619142; AA328791; BE003913;

Proteins found in more fusions

U2AF2 (see 2 fusions); NPM1 (see 1 fusions); CUL1 (see 3 fusions); SLC9A3R1 (see 2 fusions); FYN (see 1 fusions); VHL (see 1 fusions); GAN (see 1 fusions); STAT1 (see 1 fusions); SUZ12 (see 2 fusions); TRAF6 (see 1 fusions); HUWE1 (see 2 fusions); EEF1A1/RPL12 (see 1 fusions); EZH2 (see 1 fusions); PRKCE (see 3 fusions); STAU1 (see 2 fusions); EEF1A1 (see 1 fusions); NTRK1/RPL7A (see 1 fusions); CUL7 (see 2 fusions); CUL3 (see 1 fusions); PDE4D (see 2 fusions); SKI (see 1 fusions); COPS5 (see 1 fusions); RACK1/FN1 (see 1 fusions); SAT1 (see 5 fusions); SREK1 (see 4 fusions); NR3C1 (see 8 fusions); PABPC1 (see 2 fusions); PCBP2 (see 3 fusions); MCM2 (see 1 fusions); RACK1 (see 3 fusions); JAK1 (see 1 fusions); MAP3K7 (see 7 fusions);

List of active interactors

#	Name	Type	Number of PPI (degree)	Clustering Coefficient	Betweenness Centrality	Domains (Pfam, InterPro, SMART): description
1	RACK1	parental protein	195	0.107	21675.415	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
2	ADH1B	interactor	1	0	0	ADH_N (PF08240, IPR013154): Alcohol dehydrogenase GroES-like domain ADH_zinc_N (PF00107, IPR013149): Zinc-binding dehydrogenase ADH_zinc_N_2 (PF13602): Zinc-binding dehydrogenase
3	ADRB2	interactor	19	0.255	59.420	7tm_1 (PF00001, IPR000276): 7 transmembrane receptor (rhodopsin family)
4	AGTR1	suppressor	2	1.000	0	7tm_1 (PF00001, IPR000276): 7 transmembrane receptor (rhodopsin family)
5	AGTRAP	interactor	3	1.000	0	AGTRAP (PF06396, IPR009436, SM00805): Angiotensin II, type I receptor-associated protein (AGTRAP)
6	AK2	interactor	5	1.000	0	ADK (PF00406, IPR000850): Adenylate kinase AAA_33 (PF13671): AAA domain
7	ALK	oncoprotein	4	0.667	2.000	MAM (PF00629, IPR000998, SM00137): MAM domain, meprin/A5/mu Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase Ldl_recept_a (PF00057, IPR002172, SM00192): Low-density lipoprotein receptor domain class A Gly_rich (PF12810): Glycine rich protein FXa_inhibition (PF14670): Coagulation Factor Xa inhibitory site
8	ANXA2	interactor	19	0.532	16.507	Annexin (PF00191, IPR018502, SM00335): Annexin
9	AR	oncoprotein	15	0.242	41.106	Androgen_recep (PF02166, IPR001103): Androgen receptor zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
10	ARF4	interactor	12	0.455	8.475	Arf (PF00025, IPR006689, SM00177): ADP-ribosylation factor family
11	AURKB	interactor	14	0.385	21.520	Pkinase (PF00069, IPR000719): Protein kinase domain
12	BCL2L11	suppressor	8	0.429	11.333	Bclx_interact (PF08945, IPR015040): Bcl-x interacting, BH3 domain Bim_N (PF06773, IPR014771): Bim protein N-terminus
13	BMI1	oncoprotein	17	0.317	48.620	zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger) RAWUL (PF16207, IPR032443): RAWUL domain RING finger- and WD40-associated ubiquitin-like
14	BRCA1	suppressor	29	0.251	147.049	BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger) BRCT_assoc (PF12820, IPR025994): Serine-rich domain associated with BRCT
15	CAB39	interactor	3	1.000	0	Mo25 (PF08569, IPR013878): Mo25-like
16	CAND1	interactor	63	0.474	340.649	Adaptin_N (PF01602, IPR002553): Adaptin N terminal region DUF1981 (PF09324, IPR015403): Domain of unknown function (DUF1981) HEAT (PF02985, IPR000357): HEAT repeat TIP120 (PF08623, IPR013932): TATA-binding protein interacting (TIP20) RTP1_C1 (PF10363, IPR019451): Required for nuclear transport of RNA pol II C-terminus 1 DUF3385 (PF11865, IPR024585): Domain of unknown function (DUF3385) MMS19_C (PF12460, IPR024687): RNAPII transcription regulator C-terminal Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region HEAT_EZ (PF13513): HEAT-like repeat HEAT_2 (PF13646): HEAT repeats MMS19_N (PF14500): Dos2-interacting transcription regulator of RNA-Pol-II
17	CBX8	interactor	16	0.495	21.584	Atrophin-1 (PF03154, IPR002951): Atrophin-1 family Chromo (PF00385, IPR023780, SM00298): Chromo (CHRromatin Organisation MOdifier) domain RBR (PF17208): RNA binding Region CBX7_C (PF17218): CBX family C-terminal motif
18	CCDC58	interactor	7	0.600	0.900	Cid2 (PF09774, IPR019171): Caffeine-induced death protein 2
19	CCNA1	interactor	7	0.619	3.025	Cyclin_C (PF02984, IPR004367): Cyclin, C-terminal domain Cyclin_N (PF00134, IPR006671): Cyclin, N-terminal domain Cyclin_N2 (PF16500, IPR032447): N-terminal region of cyclin_N
20	CD81	interactor	30	0.525	48.654	Tetraspannin (PF00335, IPR018499): Tetraspanin family
21	CDK2	suppressor	49	0.426	220.952	Kdo (PF06293, IPR010440): Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase (PF00069, IPR000719): Protein kinase domain
22	CDKN1A	suppressor	16	0.500	21.776	CDI (PF02234, IPR003175): Cyclin-dependent kinase inhibitor
23	CFTR	suppressor	9	0.286	14.387	ABC_membrane (PF00664, IPR001140): ABC transporter transmembrane region ABC_tran (PF00005, IPR003439): ABC transporter Roc (PF08477, IPR013684): Ras of Complex, Roc, domain of DAPkinase SMC_N (PF02463, IPR003395): RecF/RecN/SMC N terminal domain Rotamase_2 (PF13145, IPR000297): PPIC-type PPIASE domain CFTR_R (PF14396, IPR025837): Cystic fibrosis TM conductance regulator (CFTR), regulator domain
24	CHERP	interactor	9	0.611	2.814	CTD_bind (PF04818, IPR006903): RNA polymerase II-binding domain. G-patch (PF01585, IPR000467, SM00443): G-patch domain HpaP (PF09483, IPR013390): Type III secretion protein (HpaP) SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit TP2 (PF01254, IPR000678): Nuclear transition protein 2 Apt1 (PF10351, IPR019443): Golgi-body localisation protein domain Surp (PF01805, IPR000061, SM00648): Surp module
25	CISH	interactor	7	0.667	5.467	SH2 (PF00017, IPR000980, SM00252): SH2 domain ER-remodelling (PF14755, IPR032786): Intracellular membrane remodeller SOCS_box (PF07525, IPR001496): SOCS box
26	COPS5	protein found in more fusions	69	0.361	665.248	JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease
27	CSF2RB	interactor	4	0.667	1.000	fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain IL4Ra_N (PF09238, IPR015319): Interleukin-4 receptor alpha chain, N-terminal IL6Ra-bind (PF09240, IPR015321): Interleukin-6 receptor alpha chain, binding Tissue_fac (PF01108, IPR003961): Tissue factor
28	CUL1	suppressor	60	0.449	331.767	Cullin (PF00888, IPR001373, SM00182): Cullin family Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
29	CUL2	suppressor	56	0.381	409.310	Cullin (PF00888, IPR001373, SM00182): Cullin family Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
30	CUL3	protein found in more fusions	71	0.375	566.301	Cullin (PF00888, IPR001373, SM00182): Cullin family Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain WAC_Acf1_DNA_bd (PF10537, IPR013136): ATP-utilising chromatin assembly and remodelling N-terminal
31	CUL7	protein found in more fusions	52	0.389	203.934	ANAPC10 (PF03256, IPR004939): Anaphase-promoting complex, subunit 10 (APC10) Cullin (PF00888, IPR001373, SM00182): Cullin family DUF1918 (PF08940, IPR015035): Domain of unknown function (DUF1918) Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain Cul7 (PF11515, IPR021097): Mouse development and cellular proliferation protein Cullin-7
32	DAZAP1	interactor	22	0.390	47.427	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2076 (PF09849, IPR018648): Uncharacterized protein conserved in bacteria (DUF2076)
33	DDX19B	interactor	2	1.000	0	DEAD (PF00270, IPR011545): DEAD/DEAH box helicase Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
34	DGCR14	interactor	1	0	0	Es2 (PF09751, IPR019148): Nuclear protein Es2
35	DYNC1LI2	interactor	8	0.571	5.574	DLIC (PF05783, IPR022780): Dynein light intermediate chain (DLIC)
36	DYNLL1	interactor	18	0.404	33.619	Dynein_light (PF01221, IPR001372): Dynein light chain type 1
37	ECT2	suppressor	6	0.533	2.495	BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain PTCB-BRCT (PF12738, IPR001357): twin BRCT domain PGBA_C (PF15437, IPR032737): Plasminogen-binding protein pgbA C-terminal
38	EEF1A1	suppressor	50	0.495	153.558	GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2 GTP_EFTU_D3 (PF03143, IPR004160): Elongation factor Tu C-terminal domain
39	EIF3E	oncoprotein	24	0.580	36.804	eIF3_N (PF09440, IPR019010): eIF3 subunit 6 N terminal domain PCI (PF01399, IPR000717, SM00088): PCI domain HD_assoc (PF13286, IPR026875): Phosphohydrolase-associated domain SPESP1 (PF15754, IPR026743): Sperm equatorial segment protein 1
40	EIF3K	interactor	5	0.600	2.138	CSN8_PSD8_EIF3K (PF10075): CSN8/PSMD8/EIF3K family
41	EIF6	interactor	20	0.600	15.538	eIF-6 (PF01912, IPR002769, SM00654): eIF-6 family
42	ELAVL1	oncoprotein	52	0.195	654.778	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
43	EPOR	oncoprotein	9	0.500	12.733	EpoR_lig-bind (PF09067, IPR015152): Erythropoietin receptor, ligand binding fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
44	ESR1	suppressor	58	0.383	412.566	Oest_recep (PF02159, IPR001292): Oestrogen receptor zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor ESR1_C (PF12743, IPR024736): Oestrogen-type nuclear receptor final C-terminal
45	EZH2	suppressor	18	0.294	59.490	CDC45 (PF02724, IPR003874): CDC45-like protein TCR (PF03638, IPR005172, SM01114): Tesmin/TSO1-like CXC domain, cysteine-rich domain SET (PF00856, IPR001214, SM00317): SET domain EZH2_WD-Binding (PF11616, IPR021654): WD repeat binding protein EZH2 Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal
46	FBXO6	interactor	29	0.392	73.069	FBA (PF04300, IPR007397): F-box associated region F-box-like (PF12937, IPR001810): F-box-like
47	FBXW2	interactor	3	1.000	0	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain F-box-like (PF12937, IPR001810): F-box-like
48	FBXW7	suppressor	12	0.255	25.220	Mem_trans (PF03547, IPR004776): Membrane transport protein WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160 F-box-like (PF12937, IPR001810): F-box-like
49	FEM1B	interactor	6	0.733	2.133	Ank (PF00023, IPR002110, SM00248): Ankyrin repeat Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_5 (PF13857): Ankyrin repeats (many copies)
50	FN1	oncoprotein	56	0.440	268.400	fn1 (PF00039, IPR000083, SM00058): Fibronectin type I domain fn2 (PF00040, IPR000562, SM00059): Fibronectin type II domain fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369)
51	FUBP1	oncoprotein	20	0.463	29.565	DUF1897 (PF09005, IPR015096): Domain of unknown function (DUF1897) KH_1 (PF00013, IPR004088, SM00322): KH domain CYSTM (PF12734, IPR028144): Cysteine-rich TM module stress tolerance
52	FYN	oncoprotein	13	0.273	39.689	Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
53	GAN	protein found in more fusions	22	0.671	19.386	BACK (PF07707, IPR011705, SM00875): BTB And C-terminal Kelch BTB (PF00651, IPR013069, SM00225): BTB/POZ domain Kelch_1 (PF01344, IPR006652, SM00612): Kelch motif Kelch_3 (PF13415): Galactose oxidase, central domain Kelch_5 (PF13854): Kelch motif
54	GLI1	suppressor	6	0.467	3.833	zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain FOXP-CC (PF16159, IPR032354): FOXP coiled-coil domain
55	GNB1	interactor	11	0.309	23.015	Myc-LZ (PF02344, IPR003327): Myc leucine zipper domain WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
56	GNG2	interactor	5	0.700	1.833	G-gamma (PF00631, IPR015898, SM00224): GGL domain SidE (PF12252, IPR021014): Dot/Icm substrate protein
57	GOLM1	interactor	1	0	0	DUF148 (PF02520, IPR003677): Domain of unknown function DUF148 Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family GreA_GreB_N (PF03449, IPR022691): Transcription elongation factor, N-terminal
58	GRAP2	interactor	2	1.000	0	NADH_dhqG_C (PF09326, IPR015405): NADH-ubiquinone oxidoreductase subunit G, C-terminal SH2 (PF00017, IPR000980, SM00252): SH2 domain DUF2076 (PF09849, IPR018648): Uncharacterized protein conserved in bacteria (DUF2076) SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
59	GRIN2B	interactor	3	0.667	1.000	ANF_receptor (PF01094, IPR001828): Receptor family ligand binding region Lig_chan (PF00060, IPR001320): Ligand-gated ion channel Lig_chan-Glu_bd (PF10613, IPR019594, SM00918): Ligated ion channel L-glutamate- and glycine-binding site NMDAR2_C (PF10565, IPR018884): N-methyl D-aspartate receptor 2B3 C-terminus
60	HABP4	interactor	3	0.667	0.667	HABP4_PAI-RBP1 (PF04774, IPR006861): Hyaluronan / mRNA binding family FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 IHABP4_N (PF16174, IPR032381): Intracellular hyaluronan-binding protein 4 N-terminal
61	HELZ	interactor	6	0.600	1.724	PAM2 (PF07145, IPR009818): Ataxin-2 C-terminal region TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat zf-CCCH (PF00642, IPR000571): Zinc finger C-x8-C-x5-C-x3-H type (and similar) AAA_11 (PF13086): AAA domain AAA_12 (PF13087): AAA domain TetR_C_8 (PF14278): Transcriptional regulator C-terminal region
62	HIF1A	suppressor	15	0.343	41.991	Dicty_REP (PF05086, IPR007778): Dictyostelium (Slime Mold) REP protein HIF-1a_CTAD (PF08778, IPR014887): HIF-1 alpha C terminal transactivation domain HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain PAS (PF00989, IPR013767, SM00091): PAS fold PAS_3 (PF08447, IPR013655): PAS fold HIF-1 (PF11413, IPR021537): Hypoxia-inducible factor-1
63	HIST1H3A	interactor	13	0.318	27.749	Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
64	HIST1H4A	interactor	17	0.426	16.449	CENP-T_C (PF15511): Centromere kinetochore component CENP-T histone fold
65	HNRNPA1	interactor	47	0.421	189.852	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HnRNPA1 (PF11627, IPR021662): Nuclear factor hnRNPA1
66	HNRNPH2	interactor	21	0.474	23.981	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RNPHF (PF08080, IPR012996): RNPHF zinc finger
67	HSD17B4	interactor	5	0.600	0.716	adh_short (PF00106, IPR002198): short chain dehydrogenase MaoC_dehydratas (PF01575, IPR002539): MaoC like domain SCP2 (PF02036, IPR003033): SCP-2 sterol transfer family MaoC_dehydrat_N (PF13452): N-terminal half of MaoC dehydratase
68	HSP90B1	suppressor	18	0.399	32.247	CobT (PF06213, IPR006538): Cobalamin biosynthesis protein CobT HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HSP90 (PF00183, IPR001404): Hsp90 protein Sigma70_ner (PF04546, IPR007631): Sigma-70, non-essential region
69	HSPA9	oncoprotein	30	0.306	91.494	HSP70 (PF00012, IPR013126): Hsp70 protein
70	HUWE1	oncoprotein	36	0.496	89.830	BUD22 (PF09073, IPR015158): BUD22 DUF908 (PF06012, IPR010309): Domain of Unknown Function (DUF908) DUF913 (PF06025, IPR010314): Domain of Unknown Function (DUF913) FdhE (PF04216, IPR006452): Protein involved in formate dehydrogenase formation HABP4_PAI-RBP1 (PF04774, IPR006861): Hyaluronan / mRNA binding family Ku_C (PF03730, IPR005160): Ku70/Ku80 C-terminal arm Merozoite_SPAM (PF07133, IPR010784): Merozoite surface protein (SPAM) Mucin (PF01456, IPR000458): Mucin-like glycoprotein Nop14 (PF04147, IPR007276): Nop14-like family PBP_sp32 (PF07222, IPR009865): Proacrosin binding protein sp32 RNA_pol_Rpc4 (PF05132, IPR007811): RNA polymerase III RPC4 TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain WWE (PF02825, IPR004170, SM00678): WWE domain HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase) Tim54 (PF11711, IPR021056): Inner membrane protein import complex subunit Tim54 U1snRNP70_N (PF12220, IPR022023): U1 small nuclear ribonucleoprotein of 70kDa MW N terminal DUF4414 (PF14377, IPR025527): Domain of unknown function (DUF4414)
71	IFNAR1	oncoprotein	3	0.667	0.500	Interfer-bind (PF09294, IPR015373): Interferon-alpha/beta receptor, fibronectin type III Tissue_fac (PF01108, IPR003961): Tissue factor
72	IFNAR2	interactor	6	0.500	4.333	Interfer-bind (PF09294, IPR015373): Interferon-alpha/beta receptor, fibronectin type III Tissue_fac (PF01108, IPR003961): Tissue factor
73	IGF1R	oncoprotein	6	0.467	3.419	fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain Furin-like (PF00757, IPR006211): Furin-like cysteine rich region Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase Recep_L_domain (PF01030, IPR000494): Receptor L domain
74	IK	interactor	9	0.536	2.155	Lsm_interact (PF05391, IPR008669): Lsm interaction motif RED_C (PF07807, IPR012492): RED-like protein C-terminal region RED_N (PF07808, IPR012916): RED-like protein N-terminal region PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
75	IL2RB	oncoprotein	5	0.500	3.500	IL6Ra-bind (PF09240, IPR015321): Interleukin-6 receptor alpha chain, binding Pur_ac_phosph_N (PF16656, IPR015914): Purple acid Phosphatase, N-terminal domain
76	IL4R	oncoprotein	2	1.000	0	fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain IL4Ra_N (PF09238, IPR015319): Interleukin-4 receptor alpha chain, N-terminal
77	IL7R	interactor	11	0.564	7.754	fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
78	ISG15	suppressor	8	0.464	4.092	ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
79	ITGB1	suppressor	9	0.361	6.186	EGF_2 (PF07974, IPR013111): EGF-like domain Integrin_b_cyt (PF08725, IPR014836): Integrin beta cytoplasmic domain Integrin_B_tail (PF07965, IPR012896): Integrin beta tail domain Integrin_beta (PF00362, IPR002369, SM00187): Integrin, beta chain PSI_integrin (PF17205): Integrin plexin domain
80	ITGB2	interactor	5	0.400	4.400	EGF_2 (PF07974, IPR013111): EGF-like domain Integrin_b_cyt (PF08725, IPR014836): Integrin beta cytoplasmic domain Integrin_B_tail (PF07965, IPR012896): Integrin beta tail domain Integrin_beta (PF00362, IPR002369, SM00187): Integrin, beta chain PSI_integrin (PF17205): Integrin plexin domain
81	JAK1	oncoprotein	14	0.295	44.004	FERM_M (PF00373, IPR019748): FERM central domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain
82	JUN	oncoprotein	14	0.359	29.822	bZIP_1 (PF00170, IPR004827): bZIP transcription factor Jun (PF03957, IPR005643): Jun-like transcription factor
83	KCNA5	interactor	6	0.500	5.000	Ion_trans (PF00520, IPR005821): Ion transport protein BTB_2 (PF02214, IPR003131): BTB/POZ domain
84	KCNAB1	interactor	3	0.667	1.000	Aldo_ket_red (PF00248, IPR023210): Aldo/keto reductase family
85	LARP4	interactor	8	0.821	0.432	La (PF05383, IPR006630, SM00715): La domain SPATIAL (PF15256): SPATIAL
86	LARP4B	interactor	8	0.821	0.435	La (PF05383, IPR006630, SM00715): La domain
87	LSM12	interactor	9	0.611	2.893	AD (PF09793, IPR019181, SM00995): Anticodon-binding domain
88	MAP2K6	interactor	3	1.000	0	Pkinase (PF00069, IPR000719): Protein kinase domain
89	MAP3K7	oncoprotein	11	0.356	19.387	Mnd1 (PF03962, IPR005647): Mnd1 family Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
90	MAPK6	oncoprotein	7	0.467	2.255	Pkinase (PF00069, IPR000719): Protein kinase domain
91	MCM2	oncoprotein	58	0.451	274.686	AAA_3 (PF07726, IPR011703): ATPase family associated with various cellular activities (AAA) MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family MCM2_N (PF12619, IPR008045): Mini-chromosome maintenance protein 2 MCM_N (PF14551, IPR027925): MCM N-terminal domain MCM_OB (PF17207): MCM OB domain
92	MDC1	suppressor	12	0.470	12.359	FHA (PF00498, IPR000253, SM00240): FHA domain DUF3274 (PF11678, IPR021692): Protein of unknown function (DUF3274) Yop-YscD_cpl (PF16697, IPR032030): Inner membrane component of T3SS, cytoplasmic domain RTT107_BRCT_5 (PF16770, IPR001357): Regulator of Ty1 transposition protein 107 BRCT domain
93	MID1	oncoprotein	10	0.556	4.830	Baculo_PEP_C (PF04513, IPR007601): Baculovirus polyhedron envelope protein, PEP, C terminus fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain SPRY (PF00622, IPR003877, SM00449): SPRY domain DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369) zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger PRY (PF13765, IPR006574, SM00589): SPRY-associated domain zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger zf-C3HC4_4 (PF15227): zinc finger of C3HC4-type, RING
94	MKI67	interactor	13	0.551	7.792	FHA (PF00498, IPR000253, SM00240): FHA domain K167R (PF08065, IPR012568): K167R (NUC007) repeat PP1_bind (PF15276, IPR029334): Protein phosphatase 1 binding AROS (PF15684, IPR023262): Active regulator of SIRT1, or 40S ribosomal protein S19-binding 1
95	MKRN2	interactor	2	1.000	0	RecR (PF02132, IPR023628): RecR protein zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger) zf-CCCH (PF00642, IPR000571): Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-rbx1 (PF12678, IPR024766): RING-H2 zinc finger domain MKRN1_C (PF15815, IPR031644): E3 ubiquitin-protein ligase makorin-1, C-terminal zf-RING_11 (PF17123, IPR001841): RING-like zinc finger
96	NPM1	suppressor	75	0.423	555.984	Nucleoplasmin (PF03066): Nucleoplasmin SDA1 (PF05285, IPR007949): SDA1 NPM1-C (PF16276, IPR032569): Nucleophosmin C-terminal domain
97	NR3C1	protein found in more fusions	10	0.333	12.558	GCR (PF02155, IPR001409): Glucocorticoid receptor zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
98	NSMAF	interactor	1	0	0	Beach (PF02138, IPR000409, SM01026): Beige/BEACH domain GRAM (PF02893, IPR004182, SM00568): GRAM domain NABP (PF07990, IPR012940): Nucleic acid binding protein NABP WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain PH_BEACH (PF14844, IPR023362): PH domain associated with Beige/BEACH
99	NTRK1	oncoprotein	71	0.298	784.010	I-set (PF07679, IPR013098): Immunoglobulin I-set domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase LRR_8 (PF13855, IPR001611): Leucine rich repeat TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain
100	OBSL1	interactor	42	0.367	116.673	BiPBP_C (PF06832, IPR009647): Penicillin-Binding Protein C-terminus Family fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain Herpes_gE (PF02480, IPR003404): Alphaherpesvirus glycoprotein E I-set (PF07679, IPR013098): Immunoglobulin I-set domain V-set (PF07686, IPR013106): Immunoglobulin V-set domain Ig_3 (PF13927): Immunoglobulin domain Ig_4 (PF16680, IPR032052): T-cell surface glycoprotein CD3 delta chain Izumo-Ig (PF16706, IPR032699): Izumo-like Immunoglobulin domain
101	OTUB1	interactor	14	0.341	29.185	Peptidase_C65 (PF10275, IPR019400): Peptidase C65 Otubain
102	PABPC1	oncoprotein	51	0.509	133.097	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP (PF00658, IPR002004, SM00517): Poly-adenylate binding protein, unique domain YflT (PF11181, IPR025889): Heat induced stress protein YflT
103	PAXIP1	interactor	12	0.409	17.736	BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain IPT (PF01745, IPR002648, SM00429): Isopentenyl transferase SURF6 (PF04935, IPR007019): Surfeit locus protein 6 DUF2052 (PF09747, IPR018613): Coiled-coil domain containing protein (DUF2052) CYSTM (PF12734, IPR028144): Cysteine-rich TM module stress tolerance PTCB-BRCT (PF12738, IPR001357): twin BRCT domain BRCT_2 (PF16589, IPR001357): BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT (PF16759, IPR031916): DNA ligase 3 BRCT domain RTT107_BRCT_5 (PF16770, IPR001357): Regulator of Ty1 transposition protein 107 BRCT domain
104	PCBP1	oncoprotein	31	0.391	85.019	Bac_chlorC (PF02043, IPR001470): Bacteriochlorophyll C binding protein KH_2 (PF07650, IPR004044): KH domain KH_1 (PF00013, IPR004088, SM00322): KH domain
105	PCBP2	protein found in more fusions	33	0.409	93.666	Bac_chlorC (PF02043, IPR001470): Bacteriochlorophyll C binding protein KH_2 (PF07650, IPR004044): KH domain KH_1 (PF00013, IPR004088, SM00322): KH domain
106	PDE4D	oncoprotein	5	0.667	1.400	Na_trans_assoc (PF06512, IPR010526): Sodium ion transport-associated PDEase_I (PF00233, IPR002073): 3'5'-cyclic nucleotide phosphodiesterase
107	PIR	interactor	4	0.667	0.348	Pirin (PF02678, IPR003829): Pirin Pirin_C (PF05726, IPR008778): Pirin C-terminal cupin domain
108	PLCG1	oncoprotein	11	0.382	22.325	C2 (PF00168, IPR000008, SM00239): C2 domain PH (PF00169, IPR001849, SM00233): PH domain SH2 (PF00017, IPR000980, SM00252): SH2 domain PI-PLC-X (PF00388, IPR000909, SM00148): Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y (PF00387, IPR001711, SM00149): Phosphatidylinositol-specific phospholipase C, Y domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain PH_12 (PF16457, IPR001849): Pleckstrin homology domain
109	PPID	interactor	9	0.444	8.225	Pro_isomerase (PF00160, IPR002130): Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat ANAPC3 (PF12895): Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 (PF13176, IPR019734): Tetratricopeptide repeat
110	PPP2R1A	oncoprotein	23	0.478	49.891	TAF6_C (PF07571, IPR011442): TAF6 C-terminal HEAT repeat domain HEAT (PF02985, IPR000357): HEAT repeat HEAT_PBS (PF03130, IPR004155, SM00567): PBS lyase HEAT-like repeat HEAT_2 (PF13646): HEAT repeats
111	PRKAB2	interactor	3	1.000	0	AMPKBI (PF04739, IPR006828, SM01010): 5'-AMP-activated protein kinase beta subunit, interaction domain AMPK1_CBM (PF16561, IPR032640): Glycogen recognition site of AMP-activated protein kinase
112	PRKCA	interactor	12	0.291	32.343	C2 (PF00168, IPR000008, SM00239): C2 domain Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain)
113	PRKCB	suppressor	8	0.286	13.000	C2 (PF00168, IPR000008, SM00239): C2 domain Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain)
114	PRKCE	suppressor	6	0.400	4.000	C2 (PF00168, IPR000008, SM00239): C2 domain Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain)
115	PRPF31	interactor	11	0.600	2.153	Nop (PF01798, IPR002687): snoRNA binding domain, fibrillarin Cytokin_check_N (PF10407, IPR018844): Cdc14 phosphatase binding protein N-terminus Prp31_C (PF09785, IPR019175): Prp31 C terminal domain
116	PTN	oncoprotein	5	0.500	3.000	PTN_MK_C (PF01091, IPR020090): PTN/MK heparin-binding protein family, C-terminal domain PTN_MK_N (PF05196, IPR020089): PTN/MK heparin-binding protein family, N-terminal domain
117	PTOV1	interactor	4	0.833	0.100	Med25 (PF11232, IPR021394): Mediator complex subunit 25 PTOV activation and synapsin 2
118	PTPRM	interactor	1	0	0	fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain ig (PF00047, IPR013151, SM00409): Immunoglobulin domain MAM (PF00629, IPR000998, SM00137): MAM domain, meprin/A5/mu Y_phosphatase (PF00102, IPR000242, SM00194): Protein-tyrosine phosphatase ECSCR (PF15820, IPR026247): Endothelial cell-specific chemotaxis regulator
119	RASA1	oncoprotein	6	0.600	3.452	C2 (PF00168, IPR000008, SM00239): C2 domain PH (PF00169, IPR001849, SM00233): PH domain RasGAP (PF00616, IPR001936, SM00323): GTPase-activator protein for Ras-like GTPase SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
120	RASA3	oncoprotein	1	0	0	BTK (PF00779, IPR001562, SM00107): BTK motif C2 (PF00168, IPR000008, SM00239): C2 domain PH (PF00169, IPR001849, SM00233): PH domain RasGAP (PF00616, IPR001936, SM00323): GTPase-activator protein for Ras-like GTPase
121	RB1	suppressor	15	0.314	39.762	RB_A (PF01858, IPR002720): Retinoblastoma-associated protein A domain RB_B (PF01857, IPR002719): Retinoblastoma-associated protein B domain Rb_C (PF08934, IPR015030): Rb C-terminal domain DUF3452 (PF11934, IPR024599): Domain of unknown function (DUF3452) DUF4592 (PF15262, IPR028030): Domain of unknown function (DUF4592)
122	RHOA	suppressor	7	0.333	9.139	Ras (PF00071, IPR001806, SM00173): Ras family
123	RIOK3	interactor	3	0.667	0.500	RIO1 (PF01163, IPR018934): RIO1 family
124	RNF185	interactor	5	0.500	2.333	zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
125	RNF2	interactor	31	0.423	85.316	zf-C4_Topoisom (PF01396, IPR013498): Topoisomerase DNA binding C4 zinc finger zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger) RAWUL (PF16207, IPR032443): RAWUL domain RING finger- and WD40-associated ubiquitin-like
126	RPL10	suppressor	57	0.578	239.392	Ribosomal_L16 (PF00252, IPR016180): Ribosomal protein L16p/L10e
127	RPL12	protein found in more fusions	51	0.693	71.290	Ribosomal_L11 (PF00298, IPR020783): Ribosomal protein L11, RNA binding domain Ribosomal_L11_N (PF03946, IPR020784): Ribosomal protein L11, N-terminal domain
128	RPL13	interactor	52	0.749	27.482	Ribosomal_L13e (PF01294, IPR001380): Ribosomal protein L13e
129	RPL15	interactor	51	0.739	37.315	Ribosomal_L15e (PF00827, IPR000439): Ribosomal L15
130	RPL19	interactor	45	0.802	15.801	DUF1682 (PF07946, IPR012879): Protein of unknown function (DUF1682) Ribosomal_L19e (PF01280, IPR000196): Ribosomal protein L19e
131	RPL21	interactor	49	0.743	52.931	Ribosomal_L21e (PF01157, IPR001147): Ribosomal protein L21e
132	RPL27A	interactor	48	0.742	42.446	Ribosomal_L27A (PF00828, IPR021131): Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A
133	RPL37A	interactor	40	0.853	11.702	Ribosomal_L37ae (PF01780, IPR002674): Ribosomal L37ae protein family
134	RPL4	interactor	54	0.695	52.667	Ribosomal_L4 (PF00573, IPR002136): Ribosomal protein L4/L1 family Ribos_L4_asso_C (PF14374, IPR025755): 60S ribosomal protein L4 C-terminal domain
135	RPL5	suppressor	55	0.702	64.303	Ribosomal_L18_c (PF14204, IPR025607): Ribosomal L18 C-terminal region Ribosomal_L5e (PF17144): Ribosomal large subunit proteins 60S L5, and 50S L18
136	RPL7	interactor	52	0.732	39.910	Ribosomal_L30 (PF00327, IPR016082): Ribosomal protein L30p/L7e Ribosomal_L30_N (PF08079, IPR012988): Ribosomal L30 N-terminal domain
137	RPL7A	protein found in more fusions	50	0.733	30.560	Ribosomal_L7Ae (PF01248, IPR004038): Ribosomal protein L7Ae/L30e/S12e/Gadd45 family
138	RPLP0	interactor	57	0.664	75.485	Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein Ribosomal_L10 (PF00466, IPR001790): Ribosomal protein L10
139	RPS12	interactor	43	0.806	20.553	Ribosomal_L7Ae (PF01248, IPR004038): Ribosomal protein L7Ae/L30e/S12e/Gadd45 family
140	RPS13	interactor	51	0.721	41.783	Ribosomal_S13_N (PF08069, IPR012606): Ribosomal S13/S15 N-terminal domain Ribosomal_S15 (PF00312, IPR000589): Ribosomal protein S15
141	RPS16	interactor	52	0.716	55.426	Ribosomal_S9 (PF00380, IPR000754): Ribosomal protein S9/S16
142	RPS18	interactor	48	0.768	36.352	Ribosomal_S13 (PF00416, IPR001892): Ribosomal protein S13/S18
143	RPS2	interactor	57	0.646	84.255	Ribosomal_S5 (PF00333, IPR013810): Ribosomal protein S5, N-terminal domain Ribosomal_S5_C (PF03719, IPR005324): Ribosomal protein S5, C-terminal domain
144	RPS20	interactor	51	0.687	96.237	Ribosomal_S10 (PF00338, IPR027486): Ribosomal protein S10p/S20e
145	RPS21	interactor	42	0.797	18.613	Ribosomal_S21e (PF01249, IPR001931): Ribosomal protein S21e
146	RPS25	interactor	50	0.718	61.058	Ribosomal_S25 (PF03297, IPR004977): S25 ribosomal protein
147	RPS27	interactor	41	0.804	23.586	Ribosomal_S27e (PF01667, IPR000592): Ribosomal protein S27 DUF3795 (PF12675, IPR024227): Protein of unknown function (DUF3795)
148	RPS27L	interactor	30	0.823	13.891	E7 (PF00527, IPR000148): E7 protein, Early protein Ribosomal_S27e (PF01667, IPR000592): Ribosomal protein S27 zf-C2HC5 (PF06221, IPR009349): Putative zinc finger motif, C2HC5-type DUF3382 (PF11862, IPR021807): Domain of unknown function (DUF3382)
149	RPS3	interactor	63	0.548	241.196	KH_2 (PF07650, IPR004044): KH domain Ribosomal_S3_C (PF00189, IPR001351): Ribosomal protein S3, C-terminal domain
150	RPS3A	interactor	59	0.667	62.595	Ribosomal_S3Ae (PF01015, IPR001593): Ribosomal S3Ae family
151	RPS5	interactor	50	0.682	74.102	Ribosomal_S7 (PF00177, IPR023798): Ribosomal protein S7p/S5e
152	RPS6	interactor	57	0.659	94.722	Ribosomal_S6e (PF01092, IPR001377): Ribosomal protein S6e DUF4574 (PF15141, IPR027896): Domain of unknown function (DUF4574)
153	RPS8	interactor	59	0.635	102.648	Ribosomal_S8e (PF01201, IPR022309): Ribosomal protein S8e
154	RPS9	interactor	54	0.693	48.860	Ribosomal_S4 (PF00163, IPR001912): Ribosomal protein S4/S9 N-terminal domain S4 (PF01479, IPR002942, SM00363): S4 domain
155	RPSA	interactor	60	0.579	170.763	Ribosomal_S2 (PF00318, IPR001865): Ribosomal protein S2 40S_SA_C (PF16122, IPR032281): 40S ribosomal protein SA C-terminus
156	SAP25	interactor	2	1.000	0	SAP25 (PF15476, IPR029163): Histone deacetylase complex subunit SAP25
157	SAT1	protein found in more fusions	5	0.500	2.667	Acetyltransf_1 (PF00583, IPR000182): Acetyltransferase (GNAT) family
158	SFN	suppressor	31	0.653	59.674	14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
159	SGTB	interactor	2	1.000	0	TOM20_plant (PF06552, IPR010547): Plant specific mitochondrial import receptor subunit TOM20 TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat XPC-binding (PF09280, IPR015360): XPC-binding domain TPR_11 (PF13414, IPR011990): TPR repeat SGTA_dimer (PF16546, IPR032374): Homodimerisation domain of SGTA
160	SIRT7	interactor	41	0.380	178.481	DUF563 (PF04577, IPR007657): Protein of unknown function (DUF563) SIR2 (PF02146, IPR003000): Sir2 family
161	SKI	oncoprotein	12	0.564	6.907	c-SKI_SMAD_bind (PF08782, IPR014890, SM01046): c-SKI Smad4 binding domain Ski_Sno (PF02437, IPR003380): SKI/SNO/DAC family SlyX (PF04102, IPR007236): SlyX HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1
162	SLC27A6	interactor	2	1.000	0	AMP-binding (PF00501, IPR000873): AMP-binding enzyme AMP-binding_C (PF13193, IPR025110): AMP-binding enzyme C-terminal domain
163	SLC9A3R1	suppressor	8	0.429	6.076	EBP50_C (PF09007, IPR015098): EBP50, C-terminal PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
164	SRC	oncoprotein	19	0.222	88.698	Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
165	SREK1	protein found in more fusions	8	0.857	0.200	Ureide_permease (PF07168, IPR009834): Ureide permease RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RP-C_C (PF11800, IPR021760): Replication protein C C-terminal region PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term DUF3915 (PF13054, IPR025026): Protein of unknown function (DUF3915) BRD4_CDT (PF17105, IPR031354): C-terminal domain of bromodomain protein 4
166	STAT1	suppressor	15	0.297	44.770	SH2 (PF00017, IPR000980, SM00252): SH2 domain STAT_alpha (PF01017, IPR013800): STAT protein, all-alpha domain STAT_bind (PF02864, IPR013801): STAT protein, DNA binding domain STAT_int (PF02865, IPR013799, SM00964): STAT protein, protein interaction domain STAT1_TAZ2bind (PF12162, IPR022752): STAT1 TAZ2 binding domain
167	STAU1	protein found in more fusions	43	0.532	109.337	dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif Staufen_C (PF16482, IPR032478): Staufen C-terminal domain
168	SUZ12	suppressor	12	0.527	10.215	DUF2070 (PF09843, IPR019204): Predicted membrane protein (DUF2070) VEFS-Box (PF09733, IPR019135): VEFS-Box of polycomb protein
169	SYN2	interactor	2	0	0	LpxD (PF04613, IPR020573): UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD SPX (PF03105, IPR004331): SPX domain Synapsin_C (PF02750, IPR020898): Synapsin, ATP binding domain Synapsin_N (PF10581, IPR019736): Synapsin N-terminal DUF2076 (PF09849, IPR018648): Uncharacterized protein conserved in bacteria (DUF2076) Synapsin (PF02078, IPR020897): Synapsin, N-terminal domain
170	SYNCRIP	interactor	35	0.387	100.872	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 (PF11608, IPR024582): Limkain b1
171	TARDBP	interactor	53	0.502	180.914	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
172	TBXA2R	interactor	6	0.500	4.500	7tm_1 (PF00001, IPR000276): 7 transmembrane receptor (rhodopsin family)
173	TCEB1	oncoprotein	15	0.381	40.991	Skp1_POZ (PF03931, IPR016073): Skp1 family, tetramerisation domain
174	TCEB2	interactor	13	0.487	20.050	ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
175	TIAL1	interactor	16	0.475	17.217	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
176	TNFRSF11A	oncoprotein	4	1.000	0	Abi (PF02517, IPR003675): CAAX protease self-immunity DAG1 (PF05454, IPR008465): Dystroglycan (Dystrophin-associated glycoprotein 1) KIX (PF02172, IPR003101): KIX domain TNFR_c6 (PF00020, IPR001368, SM00208): TNFR/NGFR cysteine-rich region
177	TNRC6C	interactor	4	1.000	0	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain Ago_hook (PF10427, IPR019486): Argonaute hook DUF3439 (PF11921, IPR024592): Domain of unknown function (DUF3439) M_domain (PF12938, IPR026805): M domain of GW182 DUF4718 (PF15842, IPR031695): Domain of unknown function (DUF4718) TNRC6-PABC_bdg (PF16608, IPR032226): TNRC6-PABC binding domain
178	TP53BP1	suppressor	10	0.422	13.084	53-BP1_Tudor (PF09038, IPR015125): Tumour suppressor p53-binding protein-1 Tudor BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain FXMRP1_C_core (PF12235, IPR022034): Fragile X-related 1 protein core C terminal DUF4772 (PF15997, IPR031940): Domain of unknown function (DUF4772) BRCT_2 (PF16589, IPR001357): BRCT domain, a BRCA1 C-terminus domain
179	TP63	suppressor	11	0.444	7.086	Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region P53 (PF00870, IPR011615): P53 DNA-binding domain P53_tetramer (PF07710, IPR010991): P53 tetramerisation motif SAM_2 (PF07647, IPR011510): SAM domain (Sterile alpha motif)
180	TP73	suppressor	9	0.536	4.405	P53 (PF00870, IPR011615): P53 DNA-binding domain P53_tetramer (PF07710, IPR010991): P53 tetramerisation motif SAM_2 (PF07647, IPR011510): SAM domain (Sterile alpha motif)
181	TRAF2	interactor	12	0.345	25.316	MATH (PF00917, IPR002083, SM00061): MATH domain Sina (PF03145, IPR018121): Seven in absentia protein family SlyX (PF04102, IPR007236): SlyX zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger) zf-TRAF (PF02176, IPR001293): TRAF-type zinc finger TRAF_BIRC3_bd (PF16673, IPR032070): TNF receptor-associated factor BIRC3 binding domain zf-C3HC4_5 (PF17121, IPR001841): Zinc finger, C3HC4 type (RING finger)
182	TRAF6	protein found in more fusions	12	0.382	25.618	SlyX (PF04102, IPR007236): SlyX zf-TRAF (PF02176, IPR001293): TRAF-type zinc finger zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
183	TRIM45	interactor	3	1.000	0	ATP-synt_ab_C (PF00306, IPR000793): ATP synthase alpha/beta chain, C terminal domain Filamin (PF00630, IPR017868): Filamin/ABP280 repeat zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger Prok-RING_4 (PF14447): Prokaryotic RING finger family 4 HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1
184	TSC22D4	interactor	6	0.333	6.125	AflR (PF08493, IPR013700): Aflatoxin regulatory protein TSC22 (PF01166, IPR000580): TSC-22/dip/bun family
185	TYK2	interactor	7	0.400	6.500	Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
186	U2AF2	protein found in more fusions	37	0.375	154.858	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Transformer (PF06495, IPR010519): Fruit fly transformer protein
187	UBE2T	interactor	3	1.000	0	UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
188	UBL4A	interactor	44	0.543	170.182	ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
189	UNK	interactor	13	0.359	15.468	MbeD_MobD (PF04899, IPR006983): MbeD/MobD like NUDE_C (PF04880, IPR006964): NUDE protein, C-terminal conserved region zf-CCCH (PF00642, IPR000571): Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF3450 (PF11932, IPR016866): Protein of unknown function (DUF3450) zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger) zf-CCCH_2 (PF14608): RNA-binding, Nab2-type zinc finger Torus (PF16131, IPR032297): Torus domain
190	VCAM1	interactor	48	0.494	121.175	C2-set (PF05790, IPR008424): Immunoglobulin C2-set domain I-set (PF07679, IPR013098): Immunoglobulin I-set domain ig (PF00047, IPR013151, SM00409): Immunoglobulin domain V-set (PF07686, IPR013106): Immunoglobulin V-set domain Ig_3 (PF13927): Immunoglobulin domain
191	VHL	suppressor	33	0.440	128.217	Trypan_PARP (PF05887, IPR008882): Procyclic acidic repetitive protein (PARP) VHL (PF01847, IPR022772): von Hippel-Lindau disease tumour suppressor protein VHL_C (PF17211): VHL box domain
192	WDR76	interactor	7	0.571	3.230	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat SPATIAL (PF15256): SPATIAL
193	WDR83	interactor	3	0.667	0.143	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
194	WIPI1	interactor	3	0.667	0.250	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat BCAS3 (PF12490, IPR022175): Breast carcinoma amplified sequence 3 ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
195	ZCCHC3	interactor	9	0.500	6.619	zf-CCHC (PF00098, IPR001878): Zinc knuckle zf-CCHC_2 (PF13696, IPR025829): Zinc knuckle

B a c k t o T o p ⇑

Fusion ID: Protein names:	RACK1
Level of PPIs:	or Upload text file:	Update repository

Examples	Cytoscape Web will replace the contents your graph	PPI Properties: Click on nodes or edges
Layout Tree Circle Radial Force Directed Preset
Export graph PDF file SVG file SIF file XML file GraphML file

Find Fusion Network

Visualization interactions

Statistics and Network structure information

List of the fusions

List of active interactors