1 |
RACK1 | parental protein | 195 | 0.107 | 21675.415 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain |
2 |
ADH1B | interactor | 1 | 0 | 0 | ADH_N (PF08240, IPR013154): Alcohol dehydrogenase GroES-like domain ADH_zinc_N (PF00107, IPR013149): Zinc-binding dehydrogenase ADH_zinc_N_2 (PF13602): Zinc-binding dehydrogenase |
3 |
ADRB2 | interactor | 19 | 0.255 | 59.420 | 7tm_1 (PF00001, IPR000276): 7 transmembrane receptor (rhodopsin family) |
4 |
AGTR1 | suppressor | 2 | 1.000 | 0 | 7tm_1 (PF00001, IPR000276): 7 transmembrane receptor (rhodopsin family) |
5 |
AGTRAP | interactor | 3 | 1.000 | 0 | AGTRAP (PF06396, IPR009436, SM00805): Angiotensin II, type I receptor-associated protein (AGTRAP) |
6 |
AK2 | interactor | 5 | 1.000 | 0 | ADK (PF00406, IPR000850): Adenylate kinase AAA_33 (PF13671): AAA domain |
7 |
ALK | oncoprotein | 4 | 0.667 | 2.000 | MAM (PF00629, IPR000998, SM00137): MAM domain, meprin/A5/mu Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase Ldl_recept_a (PF00057, IPR002172, SM00192): Low-density lipoprotein receptor domain class A Gly_rich (PF12810): Glycine rich protein FXa_inhibition (PF14670): Coagulation Factor Xa inhibitory site |
8 |
ANXA2 | interactor | 19 | 0.532 | 16.507 | Annexin (PF00191, IPR018502, SM00335): Annexin |
9 |
AR | oncoprotein | 15 | 0.242 | 41.106 | Androgen_recep (PF02166, IPR001103): Androgen receptor zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor |
10 |
ARF4 | interactor | 12 | 0.455 | 8.475 | Arf (PF00025, IPR006689, SM00177): ADP-ribosylation factor family |
11 |
AURKB | interactor | 14 | 0.385 | 21.520 | Pkinase (PF00069, IPR000719): Protein kinase domain |
12 |
BCL2L11 | suppressor | 8 | 0.429 | 11.333 | Bclx_interact (PF08945, IPR015040): Bcl-x interacting, BH3 domain Bim_N (PF06773, IPR014771): Bim protein N-terminus |
13 |
BMI1 | oncoprotein | 17 | 0.317 | 48.620 | zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger) RAWUL (PF16207, IPR032443): RAWUL domain RING finger- and WD40-associated ubiquitin-like |
14 |
BRCA1 | suppressor | 29 | 0.251 | 147.049 | BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger) BRCT_assoc (PF12820, IPR025994): Serine-rich domain associated with BRCT |
15 |
CAB39 | interactor | 3 | 1.000 | 0 | Mo25 (PF08569, IPR013878): Mo25-like |
16 |
CAND1 | interactor | 63 | 0.474 | 340.649 | Adaptin_N (PF01602, IPR002553): Adaptin N terminal region DUF1981 (PF09324, IPR015403): Domain of unknown function (DUF1981) HEAT (PF02985, IPR000357): HEAT repeat TIP120 (PF08623, IPR013932): TATA-binding protein interacting (TIP20) RTP1_C1 (PF10363, IPR019451): Required for nuclear transport of RNA pol II C-terminus 1 DUF3385 (PF11865, IPR024585): Domain of unknown function (DUF3385) MMS19_C (PF12460, IPR024687): RNAPII transcription regulator C-terminal Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region HEAT_EZ (PF13513): HEAT-like repeat HEAT_2 (PF13646): HEAT repeats MMS19_N (PF14500): Dos2-interacting transcription regulator of RNA-Pol-II |
17 |
CBX8 | interactor | 16 | 0.495 | 21.584 | Atrophin-1 (PF03154, IPR002951): Atrophin-1 family Chromo (PF00385, IPR023780, SM00298): Chromo (CHRromatin Organisation MOdifier) domain RBR (PF17208): RNA binding Region CBX7_C (PF17218): CBX family C-terminal motif |
18 |
CCDC58 | interactor | 7 | 0.600 | 0.900 | Cid2 (PF09774, IPR019171): Caffeine-induced death protein 2 |
19 |
CCNA1 | interactor | 7 | 0.619 | 3.025 | Cyclin_C (PF02984, IPR004367): Cyclin, C-terminal domain Cyclin_N (PF00134, IPR006671): Cyclin, N-terminal domain Cyclin_N2 (PF16500, IPR032447): N-terminal region of cyclin_N |
20 |
CD81 | interactor | 30 | 0.525 | 48.654 | Tetraspannin (PF00335, IPR018499): Tetraspanin family |
21 |
CDK2 | suppressor | 49 | 0.426 | 220.952 | Kdo (PF06293, IPR010440): Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase (PF00069, IPR000719): Protein kinase domain |
22 |
CDKN1A | suppressor | 16 | 0.500 | 21.776 | CDI (PF02234, IPR003175): Cyclin-dependent kinase inhibitor |
23 |
CFTR | suppressor | 9 | 0.286 | 14.387 | ABC_membrane (PF00664, IPR001140): ABC transporter transmembrane region ABC_tran (PF00005, IPR003439): ABC transporter Roc (PF08477, IPR013684): Ras of Complex, Roc, domain of DAPkinase SMC_N (PF02463, IPR003395): RecF/RecN/SMC N terminal domain Rotamase_2 (PF13145, IPR000297): PPIC-type PPIASE domain CFTR_R (PF14396, IPR025837): Cystic fibrosis TM conductance regulator (CFTR), regulator domain |
24 |
CHERP | interactor | 9 | 0.611 | 2.814 | CTD_bind (PF04818, IPR006903): RNA polymerase II-binding domain. G-patch (PF01585, IPR000467, SM00443): G-patch domain HpaP (PF09483, IPR013390): Type III secretion protein (HpaP) SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit TP2 (PF01254, IPR000678): Nuclear transition protein 2 Apt1 (PF10351, IPR019443): Golgi-body localisation protein domain Surp (PF01805, IPR000061, SM00648): Surp module |
25 |
CISH | interactor | 7 | 0.667 | 5.467 | SH2 (PF00017, IPR000980, SM00252): SH2 domain ER-remodelling (PF14755, IPR032786): Intracellular membrane remodeller SOCS_box (PF07525, IPR001496): SOCS box |
26 |
COPS5 | protein found in more fusions | 69 | 0.361 | 665.248 | JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease |
27 |
CSF2RB | interactor | 4 | 0.667 | 1.000 | fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain IL4Ra_N (PF09238, IPR015319): Interleukin-4 receptor alpha chain, N-terminal IL6Ra-bind (PF09240, IPR015321): Interleukin-6 receptor alpha chain, binding Tissue_fac (PF01108, IPR003961): Tissue factor |
28 |
CUL1 | suppressor | 60 | 0.449 | 331.767 | Cullin (PF00888, IPR001373, SM00182): Cullin family Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain |
29 |
CUL2 | suppressor | 56 | 0.381 | 409.310 | Cullin (PF00888, IPR001373, SM00182): Cullin family Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain |
30 |
CUL3 | protein found in more fusions | 71 | 0.375 | 566.301 | Cullin (PF00888, IPR001373, SM00182): Cullin family Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain WAC_Acf1_DNA_bd (PF10537, IPR013136): ATP-utilising chromatin assembly and remodelling N-terminal |
31 |
CUL7 | protein found in more fusions | 52 | 0.389 | 203.934 | ANAPC10 (PF03256, IPR004939): Anaphase-promoting complex, subunit 10 (APC10) Cullin (PF00888, IPR001373, SM00182): Cullin family DUF1918 (PF08940, IPR015035): Domain of unknown function (DUF1918) Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain Cul7 (PF11515, IPR021097): Mouse development and cellular proliferation protein Cullin-7 |
32 |
DAZAP1 | interactor | 22 | 0.390 | 47.427 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2076 (PF09849, IPR018648): Uncharacterized protein conserved in bacteria (DUF2076) |
33 |
DDX19B | interactor | 2 | 1.000 | 0 | DEAD (PF00270, IPR011545): DEAD/DEAH box helicase Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain |
34 |
DGCR14 | interactor | 1 | 0 | 0 | Es2 (PF09751, IPR019148): Nuclear protein Es2 |
35 |
DYNC1LI2 | interactor | 8 | 0.571 | 5.574 | DLIC (PF05783, IPR022780): Dynein light intermediate chain (DLIC) |
36 |
DYNLL1 | interactor | 18 | 0.404 | 33.619 | Dynein_light (PF01221, IPR001372): Dynein light chain type 1 |
37 |
ECT2 | suppressor | 6 | 0.533 | 2.495 | BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain PTCB-BRCT (PF12738, IPR001357): twin BRCT domain PGBA_C (PF15437, IPR032737): Plasminogen-binding protein pgbA C-terminal |
38 |
EEF1A1 | suppressor | 50 | 0.495 | 153.558 | GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2 GTP_EFTU_D3 (PF03143, IPR004160): Elongation factor Tu C-terminal domain |
39 |
EIF3E | oncoprotein | 24 | 0.580 | 36.804 | eIF3_N (PF09440, IPR019010): eIF3 subunit 6 N terminal domain PCI (PF01399, IPR000717, SM00088): PCI domain HD_assoc (PF13286, IPR026875): Phosphohydrolase-associated domain SPESP1 (PF15754, IPR026743): Sperm equatorial segment protein 1 |
40 |
EIF3K | interactor | 5 | 0.600 | 2.138 | CSN8_PSD8_EIF3K (PF10075): CSN8/PSMD8/EIF3K family |
41 |
EIF6 | interactor | 20 | 0.600 | 15.538 | eIF-6 (PF01912, IPR002769, SM00654): eIF-6 family |
42 |
ELAVL1 | oncoprotein | 52 | 0.195 | 654.778 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
43 |
EPOR | oncoprotein | 9 | 0.500 | 12.733 | EpoR_lig-bind (PF09067, IPR015152): Erythropoietin receptor, ligand binding fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain |
44 |
ESR1 | suppressor | 58 | 0.383 | 412.566 | Oest_recep (PF02159, IPR001292): Oestrogen receptor zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor ESR1_C (PF12743, IPR024736): Oestrogen-type nuclear receptor final C-terminal |
45 |
EZH2 | suppressor | 18 | 0.294 | 59.490 | CDC45 (PF02724, IPR003874): CDC45-like protein TCR (PF03638, IPR005172, SM01114): Tesmin/TSO1-like CXC domain, cysteine-rich domain SET (PF00856, IPR001214, SM00317): SET domain EZH2_WD-Binding (PF11616, IPR021654): WD repeat binding protein EZH2 Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal |
46 |
FBXO6 | interactor | 29 | 0.392 | 73.069 | FBA (PF04300, IPR007397): F-box associated region F-box-like (PF12937, IPR001810): F-box-like |
47 |
FBXW2 | interactor | 3 | 1.000 | 0 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain F-box-like (PF12937, IPR001810): F-box-like |
48 |
FBXW7 | suppressor | 12 | 0.255 | 25.220 | Mem_trans (PF03547, IPR004776): Membrane transport protein WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160 F-box-like (PF12937, IPR001810): F-box-like |
49 |
FEM1B | interactor | 6 | 0.733 | 2.133 | Ank (PF00023, IPR002110, SM00248): Ankyrin repeat Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_5 (PF13857): Ankyrin repeats (many copies) |
50 |
FN1 | oncoprotein | 56 | 0.440 | 268.400 | fn1 (PF00039, IPR000083, SM00058): Fibronectin type I domain fn2 (PF00040, IPR000562, SM00059): Fibronectin type II domain fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369) |
51 |
FUBP1 | oncoprotein | 20 | 0.463 | 29.565 | DUF1897 (PF09005, IPR015096): Domain of unknown function (DUF1897) KH_1 (PF00013, IPR004088, SM00322): KH domain CYSTM (PF12734, IPR028144): Cysteine-rich TM module stress tolerance |
52 |
FYN | oncoprotein | 13 | 0.273 | 39.689 | Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain |
53 |
GAN | protein found in more fusions | 22 | 0.671 | 19.386 | BACK (PF07707, IPR011705, SM00875): BTB And C-terminal Kelch BTB (PF00651, IPR013069, SM00225): BTB/POZ domain Kelch_1 (PF01344, IPR006652, SM00612): Kelch motif Kelch_3 (PF13415): Galactose oxidase, central domain Kelch_5 (PF13854): Kelch motif |
54 |
GLI1 | suppressor | 6 | 0.467 | 3.833 | zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain FOXP-CC (PF16159, IPR032354): FOXP coiled-coil domain |
55 |
GNB1 | interactor | 11 | 0.309 | 23.015 | Myc-LZ (PF02344, IPR003327): Myc leucine zipper domain WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat |
56 |
GNG2 | interactor | 5 | 0.700 | 1.833 | G-gamma (PF00631, IPR015898, SM00224): GGL domain SidE (PF12252, IPR021014): Dot/Icm substrate protein |
57 |
GOLM1 | interactor | 1 | 0 | 0 | DUF148 (PF02520, IPR003677): Domain of unknown function DUF148 Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family GreA_GreB_N (PF03449, IPR022691): Transcription elongation factor, N-terminal |
58 |
GRAP2 | interactor | 2 | 1.000 | 0 | NADH_dhqG_C (PF09326, IPR015405): NADH-ubiquinone oxidoreductase subunit G, C-terminal SH2 (PF00017, IPR000980, SM00252): SH2 domain DUF2076 (PF09849, IPR018648): Uncharacterized protein conserved in bacteria (DUF2076) SH3_1 (PF00018, IPR001452, SM00326): SH3 domain |
59 |
GRIN2B | interactor | 3 | 0.667 | 1.000 | ANF_receptor (PF01094, IPR001828): Receptor family ligand binding region Lig_chan (PF00060, IPR001320): Ligand-gated ion channel Lig_chan-Glu_bd (PF10613, IPR019594, SM00918): Ligated ion channel L-glutamate- and glycine-binding site NMDAR2_C (PF10565, IPR018884): N-methyl D-aspartate receptor 2B3 C-terminus |
60 |
HABP4 | interactor | 3 | 0.667 | 0.667 | HABP4_PAI-RBP1 (PF04774, IPR006861): Hyaluronan / mRNA binding family FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 IHABP4_N (PF16174, IPR032381): Intracellular hyaluronan-binding protein 4 N-terminal |
61 |
HELZ | interactor | 6 | 0.600 | 1.724 | PAM2 (PF07145, IPR009818): Ataxin-2 C-terminal region TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat zf-CCCH (PF00642, IPR000571): Zinc finger C-x8-C-x5-C-x3-H type (and similar) AAA_11 (PF13086): AAA domain AAA_12 (PF13087): AAA domain TetR_C_8 (PF14278): Transcriptional regulator C-terminal region |
62 |
HIF1A | suppressor | 15 | 0.343 | 41.991 | Dicty_REP (PF05086, IPR007778): Dictyostelium (Slime Mold) REP protein HIF-1a_CTAD (PF08778, IPR014887): HIF-1 alpha C terminal transactivation domain HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain PAS (PF00989, IPR013767, SM00091): PAS fold PAS_3 (PF08447, IPR013655): PAS fold HIF-1 (PF11413, IPR021537): Hypoxia-inducible factor-1 |
63 |
HIST1H3A | interactor | 13 | 0.318 | 27.749 | Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4 |
64 |
HIST1H4A | interactor | 17 | 0.426 | 16.449 | CENP-T_C (PF15511): Centromere kinetochore component CENP-T histone fold |
65 |
HNRNPA1 | interactor | 47 | 0.421 | 189.852 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HnRNPA1 (PF11627, IPR021662): Nuclear factor hnRNPA1 |
66 |
HNRNPH2 | interactor | 21 | 0.474 | 23.981 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RNPHF (PF08080, IPR012996): RNPHF zinc finger |
67 |
HSD17B4 | interactor | 5 | 0.600 | 0.716 | adh_short (PF00106, IPR002198): short chain dehydrogenase MaoC_dehydratas (PF01575, IPR002539): MaoC like domain SCP2 (PF02036, IPR003033): SCP-2 sterol transfer family MaoC_dehydrat_N (PF13452): N-terminal half of MaoC dehydratase |
68 |
HSP90B1 | suppressor | 18 | 0.399 | 32.247 | CobT (PF06213, IPR006538): Cobalamin biosynthesis protein CobT HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HSP90 (PF00183, IPR001404): Hsp90 protein Sigma70_ner (PF04546, IPR007631): Sigma-70, non-essential region |
69 |
HSPA9 | oncoprotein | 30 | 0.306 | 91.494 | HSP70 (PF00012, IPR013126): Hsp70 protein |
70 |
HUWE1 | oncoprotein | 36 | 0.496 | 89.830 | BUD22 (PF09073, IPR015158): BUD22 DUF908 (PF06012, IPR010309): Domain of Unknown Function (DUF908) DUF913 (PF06025, IPR010314): Domain of Unknown Function (DUF913) FdhE (PF04216, IPR006452): Protein involved in formate dehydrogenase formation HABP4_PAI-RBP1 (PF04774, IPR006861): Hyaluronan / mRNA binding family Ku_C (PF03730, IPR005160): Ku70/Ku80 C-terminal arm Merozoite_SPAM (PF07133, IPR010784): Merozoite surface protein (SPAM) Mucin (PF01456, IPR000458): Mucin-like glycoprotein Nop14 (PF04147, IPR007276): Nop14-like family PBP_sp32 (PF07222, IPR009865): Proacrosin binding protein sp32 RNA_pol_Rpc4 (PF05132, IPR007811): RNA polymerase III RPC4 TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain WWE (PF02825, IPR004170, SM00678): WWE domain HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase) Tim54 (PF11711, IPR021056): Inner membrane protein import complex subunit Tim54 U1snRNP70_N (PF12220, IPR022023): U1 small nuclear ribonucleoprotein of 70kDa MW N terminal DUF4414 (PF14377, IPR025527): Domain of unknown function (DUF4414) |
71 |
IFNAR1 | oncoprotein | 3 | 0.667 | 0.500 | Interfer-bind (PF09294, IPR015373): Interferon-alpha/beta receptor, fibronectin type III Tissue_fac (PF01108, IPR003961): Tissue factor |
72 |
IFNAR2 | interactor | 6 | 0.500 | 4.333 | Interfer-bind (PF09294, IPR015373): Interferon-alpha/beta receptor, fibronectin type III Tissue_fac (PF01108, IPR003961): Tissue factor |
73 |
IGF1R | oncoprotein | 6 | 0.467 | 3.419 | fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain Furin-like (PF00757, IPR006211): Furin-like cysteine rich region Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase Recep_L_domain (PF01030, IPR000494): Receptor L domain |
74 |
IK | interactor | 9 | 0.536 | 2.155 | Lsm_interact (PF05391, IPR008669): Lsm interaction motif RED_C (PF07807, IPR012492): RED-like protein C-terminal region RED_N (PF07808, IPR012916): RED-like protein N-terminal region PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term |
75 |
IL2RB | oncoprotein | 5 | 0.500 | 3.500 | IL6Ra-bind (PF09240, IPR015321): Interleukin-6 receptor alpha chain, binding Pur_ac_phosph_N (PF16656, IPR015914): Purple acid Phosphatase, N-terminal domain |
76 |
IL4R | oncoprotein | 2 | 1.000 | 0 | fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain IL4Ra_N (PF09238, IPR015319): Interleukin-4 receptor alpha chain, N-terminal |
77 |
IL7R | interactor | 11 | 0.564 | 7.754 | fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain |
78 |
ISG15 | suppressor | 8 | 0.464 | 4.092 | ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family |
79 |
ITGB1 | suppressor | 9 | 0.361 | 6.186 | EGF_2 (PF07974, IPR013111): EGF-like domain Integrin_b_cyt (PF08725, IPR014836): Integrin beta cytoplasmic domain Integrin_B_tail (PF07965, IPR012896): Integrin beta tail domain Integrin_beta (PF00362, IPR002369, SM00187): Integrin, beta chain PSI_integrin (PF17205): Integrin plexin domain |
80 |
ITGB2 | interactor | 5 | 0.400 | 4.400 | EGF_2 (PF07974, IPR013111): EGF-like domain Integrin_b_cyt (PF08725, IPR014836): Integrin beta cytoplasmic domain Integrin_B_tail (PF07965, IPR012896): Integrin beta tail domain Integrin_beta (PF00362, IPR002369, SM00187): Integrin, beta chain PSI_integrin (PF17205): Integrin plexin domain |
81 |
JAK1 | oncoprotein | 14 | 0.295 | 44.004 | FERM_M (PF00373, IPR019748): FERM central domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain |
82 |
JUN | oncoprotein | 14 | 0.359 | 29.822 | bZIP_1 (PF00170, IPR004827): bZIP transcription factor Jun (PF03957, IPR005643): Jun-like transcription factor |
83 |
KCNA5 | interactor | 6 | 0.500 | 5.000 | Ion_trans (PF00520, IPR005821): Ion transport protein BTB_2 (PF02214, IPR003131): BTB/POZ domain |
84 |
KCNAB1 | interactor | 3 | 0.667 | 1.000 | Aldo_ket_red (PF00248, IPR023210): Aldo/keto reductase family |
85 |
LARP4 | interactor | 8 | 0.821 | 0.432 | La (PF05383, IPR006630, SM00715): La domain SPATIAL (PF15256): SPATIAL |
86 |
LARP4B | interactor | 8 | 0.821 | 0.435 | La (PF05383, IPR006630, SM00715): La domain |
87 |
LSM12 | interactor | 9 | 0.611 | 2.893 | AD (PF09793, IPR019181, SM00995): Anticodon-binding domain |
88 |
MAP2K6 | interactor | 3 | 1.000 | 0 | Pkinase (PF00069, IPR000719): Protein kinase domain |
89 |
MAP3K7 | oncoprotein | 11 | 0.356 | 19.387 | Mnd1 (PF03962, IPR005647): Mnd1 family Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase |
90 |
MAPK6 | oncoprotein | 7 | 0.467 | 2.255 | Pkinase (PF00069, IPR000719): Protein kinase domain |
91 |
MCM2 | oncoprotein | 58 | 0.451 | 274.686 | AAA_3 (PF07726, IPR011703): ATPase family associated with various cellular activities (AAA) MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family MCM2_N (PF12619, IPR008045): Mini-chromosome maintenance protein 2 MCM_N (PF14551, IPR027925): MCM N-terminal domain MCM_OB (PF17207): MCM OB domain |
92 |
MDC1 | suppressor | 12 | 0.470 | 12.359 | FHA (PF00498, IPR000253, SM00240): FHA domain DUF3274 (PF11678, IPR021692): Protein of unknown function (DUF3274) Yop-YscD_cpl (PF16697, IPR032030): Inner membrane component of T3SS, cytoplasmic domain RTT107_BRCT_5 (PF16770, IPR001357): Regulator of Ty1 transposition protein 107 BRCT domain |
93 |
MID1 | oncoprotein | 10 | 0.556 | 4.830 | Baculo_PEP_C (PF04513, IPR007601): Baculovirus polyhedron envelope protein, PEP, C terminus fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain SPRY (PF00622, IPR003877, SM00449): SPRY domain DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369) zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger PRY (PF13765, IPR006574, SM00589): SPRY-associated domain zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger zf-C3HC4_4 (PF15227): zinc finger of C3HC4-type, RING |
94 |
MKI67 | interactor | 13 | 0.551 | 7.792 | FHA (PF00498, IPR000253, SM00240): FHA domain K167R (PF08065, IPR012568): K167R (NUC007) repeat PP1_bind (PF15276, IPR029334): Protein phosphatase 1 binding AROS (PF15684, IPR023262): Active regulator of SIRT1, or 40S ribosomal protein S19-binding 1 |
95 |
MKRN2 | interactor | 2 | 1.000 | 0 | RecR (PF02132, IPR023628): RecR protein zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger) zf-CCCH (PF00642, IPR000571): Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-rbx1 (PF12678, IPR024766): RING-H2 zinc finger domain MKRN1_C (PF15815, IPR031644): E3 ubiquitin-protein ligase makorin-1, C-terminal zf-RING_11 (PF17123, IPR001841): RING-like zinc finger |
96 |
NPM1 | suppressor | 75 | 0.423 | 555.984 | Nucleoplasmin (PF03066): Nucleoplasmin SDA1 (PF05285, IPR007949): SDA1 NPM1-C (PF16276, IPR032569): Nucleophosmin C-terminal domain |
97 |
NR3C1 | protein found in more fusions | 10 | 0.333 | 12.558 | GCR (PF02155, IPR001409): Glucocorticoid receptor zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor |
98 |
NSMAF | interactor | 1 | 0 | 0 | Beach (PF02138, IPR000409, SM01026): Beige/BEACH domain GRAM (PF02893, IPR004182, SM00568): GRAM domain NABP (PF07990, IPR012940): Nucleic acid binding protein NABP WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain PH_BEACH (PF14844, IPR023362): PH domain associated with Beige/BEACH |
99 |
NTRK1 | oncoprotein | 71 | 0.298 | 784.010 | I-set (PF07679, IPR013098): Immunoglobulin I-set domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase LRR_8 (PF13855, IPR001611): Leucine rich repeat TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain |
100 |
OBSL1 | interactor | 42 | 0.367 | 116.673 | BiPBP_C (PF06832, IPR009647): Penicillin-Binding Protein C-terminus Family fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain Herpes_gE (PF02480, IPR003404): Alphaherpesvirus glycoprotein E I-set (PF07679, IPR013098): Immunoglobulin I-set domain V-set (PF07686, IPR013106): Immunoglobulin V-set domain Ig_3 (PF13927): Immunoglobulin domain Ig_4 (PF16680, IPR032052): T-cell surface glycoprotein CD3 delta chain Izumo-Ig (PF16706, IPR032699): Izumo-like Immunoglobulin domain |
101 |
OTUB1 | interactor | 14 | 0.341 | 29.185 | Peptidase_C65 (PF10275, IPR019400): Peptidase C65 Otubain |
102 |
PABPC1 | oncoprotein | 51 | 0.509 | 133.097 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP (PF00658, IPR002004, SM00517): Poly-adenylate binding protein, unique domain YflT (PF11181, IPR025889): Heat induced stress protein YflT |
103 |
PAXIP1 | interactor | 12 | 0.409 | 17.736 | BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain IPT (PF01745, IPR002648, SM00429): Isopentenyl transferase SURF6 (PF04935, IPR007019): Surfeit locus protein 6 DUF2052 (PF09747, IPR018613): Coiled-coil domain containing protein (DUF2052) CYSTM (PF12734, IPR028144): Cysteine-rich TM module stress tolerance PTCB-BRCT (PF12738, IPR001357): twin BRCT domain BRCT_2 (PF16589, IPR001357): BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT (PF16759, IPR031916): DNA ligase 3 BRCT domain RTT107_BRCT_5 (PF16770, IPR001357): Regulator of Ty1 transposition protein 107 BRCT domain |
104 |
PCBP1 | oncoprotein | 31 | 0.391 | 85.019 | Bac_chlorC (PF02043, IPR001470): Bacteriochlorophyll C binding protein KH_2 (PF07650, IPR004044): KH domain KH_1 (PF00013, IPR004088, SM00322): KH domain |
105 |
PCBP2 | protein found in more fusions | 33 | 0.409 | 93.666 | Bac_chlorC (PF02043, IPR001470): Bacteriochlorophyll C binding protein KH_2 (PF07650, IPR004044): KH domain KH_1 (PF00013, IPR004088, SM00322): KH domain |
106 |
PDE4D | oncoprotein | 5 | 0.667 | 1.400 | Na_trans_assoc (PF06512, IPR010526): Sodium ion transport-associated PDEase_I (PF00233, IPR002073): 3'5'-cyclic nucleotide phosphodiesterase |
107 |
PIR | interactor | 4 | 0.667 | 0.348 | Pirin (PF02678, IPR003829): Pirin Pirin_C (PF05726, IPR008778): Pirin C-terminal cupin domain |
108 |
PLCG1 | oncoprotein | 11 | 0.382 | 22.325 | C2 (PF00168, IPR000008, SM00239): C2 domain PH (PF00169, IPR001849, SM00233): PH domain SH2 (PF00017, IPR000980, SM00252): SH2 domain PI-PLC-X (PF00388, IPR000909, SM00148): Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y (PF00387, IPR001711, SM00149): Phosphatidylinositol-specific phospholipase C, Y domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain PH_12 (PF16457, IPR001849): Pleckstrin homology domain |
109 |
PPID | interactor | 9 | 0.444 | 8.225 | Pro_isomerase (PF00160, IPR002130): Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat ANAPC3 (PF12895): Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 (PF13176, IPR019734): Tetratricopeptide repeat |
110 |
PPP2R1A | oncoprotein | 23 | 0.478 | 49.891 | TAF6_C (PF07571, IPR011442): TAF6 C-terminal HEAT repeat domain HEAT (PF02985, IPR000357): HEAT repeat HEAT_PBS (PF03130, IPR004155, SM00567): PBS lyase HEAT-like repeat HEAT_2 (PF13646): HEAT repeats |
111 |
PRKAB2 | interactor | 3 | 1.000 | 0 | AMPKBI (PF04739, IPR006828, SM01010): 5'-AMP-activated protein kinase beta subunit, interaction domain AMPK1_CBM (PF16561, IPR032640): Glycogen recognition site of AMP-activated protein kinase |
112 |
PRKCA | interactor | 12 | 0.291 | 32.343 | C2 (PF00168, IPR000008, SM00239): C2 domain Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain) |
113 |
PRKCB | suppressor | 8 | 0.286 | 13.000 | C2 (PF00168, IPR000008, SM00239): C2 domain Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain) |
114 |
PRKCE | suppressor | 6 | 0.400 | 4.000 | C2 (PF00168, IPR000008, SM00239): C2 domain Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain) |
115 |
PRPF31 | interactor | 11 | 0.600 | 2.153 | Nop (PF01798, IPR002687): snoRNA binding domain, fibrillarin Cytokin_check_N (PF10407, IPR018844): Cdc14 phosphatase binding protein N-terminus Prp31_C (PF09785, IPR019175): Prp31 C terminal domain |
116 |
PTN | oncoprotein | 5 | 0.500 | 3.000 | PTN_MK_C (PF01091, IPR020090): PTN/MK heparin-binding protein family, C-terminal domain PTN_MK_N (PF05196, IPR020089): PTN/MK heparin-binding protein family, N-terminal domain |
117 |
PTOV1 | interactor | 4 | 0.833 | 0.100 | Med25 (PF11232, IPR021394): Mediator complex subunit 25 PTOV activation and synapsin 2 |
118 |
PTPRM | interactor | 1 | 0 | 0 | fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain ig (PF00047, IPR013151, SM00409): Immunoglobulin domain MAM (PF00629, IPR000998, SM00137): MAM domain, meprin/A5/mu Y_phosphatase (PF00102, IPR000242, SM00194): Protein-tyrosine phosphatase ECSCR (PF15820, IPR026247): Endothelial cell-specific chemotaxis regulator |
119 |
RASA1 | oncoprotein | 6 | 0.600 | 3.452 | C2 (PF00168, IPR000008, SM00239): C2 domain PH (PF00169, IPR001849, SM00233): PH domain RasGAP (PF00616, IPR001936, SM00323): GTPase-activator protein for Ras-like GTPase SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain |
120 |
RASA3 | oncoprotein | 1 | 0 | 0 | BTK (PF00779, IPR001562, SM00107): BTK motif C2 (PF00168, IPR000008, SM00239): C2 domain PH (PF00169, IPR001849, SM00233): PH domain RasGAP (PF00616, IPR001936, SM00323): GTPase-activator protein for Ras-like GTPase |
121 |
RB1 | suppressor | 15 | 0.314 | 39.762 | RB_A (PF01858, IPR002720): Retinoblastoma-associated protein A domain RB_B (PF01857, IPR002719): Retinoblastoma-associated protein B domain Rb_C (PF08934, IPR015030): Rb C-terminal domain DUF3452 (PF11934, IPR024599): Domain of unknown function (DUF3452) DUF4592 (PF15262, IPR028030): Domain of unknown function (DUF4592) |
122 |
RHOA | suppressor | 7 | 0.333 | 9.139 | Ras (PF00071, IPR001806, SM00173): Ras family |
123 |
RIOK3 | interactor | 3 | 0.667 | 0.500 | RIO1 (PF01163, IPR018934): RIO1 family |
124 |
RNF185 | interactor | 5 | 0.500 | 2.333 | zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger) |
125 |
RNF2 | interactor | 31 | 0.423 | 85.316 | zf-C4_Topoisom (PF01396, IPR013498): Topoisomerase DNA binding C4 zinc finger zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger) RAWUL (PF16207, IPR032443): RAWUL domain RING finger- and WD40-associated ubiquitin-like |
126 |
RPL10 | suppressor | 57 | 0.578 | 239.392 | Ribosomal_L16 (PF00252, IPR016180): Ribosomal protein L16p/L10e |
127 |
RPL12 | protein found in more fusions | 51 | 0.693 | 71.290 | Ribosomal_L11 (PF00298, IPR020783): Ribosomal protein L11, RNA binding domain Ribosomal_L11_N (PF03946, IPR020784): Ribosomal protein L11, N-terminal domain |
128 |
RPL13 | interactor | 52 | 0.749 | 27.482 | Ribosomal_L13e (PF01294, IPR001380): Ribosomal protein L13e |
129 |
RPL15 | interactor | 51 | 0.739 | 37.315 | Ribosomal_L15e (PF00827, IPR000439): Ribosomal L15 |
130 |
RPL19 | interactor | 45 | 0.802 | 15.801 | DUF1682 (PF07946, IPR012879): Protein of unknown function (DUF1682) Ribosomal_L19e (PF01280, IPR000196): Ribosomal protein L19e |
131 |
RPL21 | interactor | 49 | 0.743 | 52.931 | Ribosomal_L21e (PF01157, IPR001147): Ribosomal protein L21e |
132 |
RPL27A | interactor | 48 | 0.742 | 42.446 | Ribosomal_L27A (PF00828, IPR021131): Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A |
133 |
RPL37A | interactor | 40 | 0.853 | 11.702 | Ribosomal_L37ae (PF01780, IPR002674): Ribosomal L37ae protein family |
134 |
RPL4 | interactor | 54 | 0.695 | 52.667 | Ribosomal_L4 (PF00573, IPR002136): Ribosomal protein L4/L1 family Ribos_L4_asso_C (PF14374, IPR025755): 60S ribosomal protein L4 C-terminal domain |
135 |
RPL5 | suppressor | 55 | 0.702 | 64.303 | Ribosomal_L18_c (PF14204, IPR025607): Ribosomal L18 C-terminal region Ribosomal_L5e (PF17144): Ribosomal large subunit proteins 60S L5, and 50S L18 |
136 |
RPL7 | interactor | 52 | 0.732 | 39.910 | Ribosomal_L30 (PF00327, IPR016082): Ribosomal protein L30p/L7e Ribosomal_L30_N (PF08079, IPR012988): Ribosomal L30 N-terminal domain |
137 |
RPL7A | protein found in more fusions | 50 | 0.733 | 30.560 | Ribosomal_L7Ae (PF01248, IPR004038): Ribosomal protein L7Ae/L30e/S12e/Gadd45 family |
138 |
RPLP0 | interactor | 57 | 0.664 | 75.485 | Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein Ribosomal_L10 (PF00466, IPR001790): Ribosomal protein L10 |
139 |
RPS12 | interactor | 43 | 0.806 | 20.553 | Ribosomal_L7Ae (PF01248, IPR004038): Ribosomal protein L7Ae/L30e/S12e/Gadd45 family |
140 |
RPS13 | interactor | 51 | 0.721 | 41.783 | Ribosomal_S13_N (PF08069, IPR012606): Ribosomal S13/S15 N-terminal domain Ribosomal_S15 (PF00312, IPR000589): Ribosomal protein S15 |
141 |
RPS16 | interactor | 52 | 0.716 | 55.426 | Ribosomal_S9 (PF00380, IPR000754): Ribosomal protein S9/S16 |
142 |
RPS18 | interactor | 48 | 0.768 | 36.352 | Ribosomal_S13 (PF00416, IPR001892): Ribosomal protein S13/S18 |
143 |
RPS2 | interactor | 57 | 0.646 | 84.255 | Ribosomal_S5 (PF00333, IPR013810): Ribosomal protein S5, N-terminal domain Ribosomal_S5_C (PF03719, IPR005324): Ribosomal protein S5, C-terminal domain |
144 |
RPS20 | interactor | 51 | 0.687 | 96.237 | Ribosomal_S10 (PF00338, IPR027486): Ribosomal protein S10p/S20e |
145 |
RPS21 | interactor | 42 | 0.797 | 18.613 | Ribosomal_S21e (PF01249, IPR001931): Ribosomal protein S21e |
146 |
RPS25 | interactor | 50 | 0.718 | 61.058 | Ribosomal_S25 (PF03297, IPR004977): S25 ribosomal protein |
147 |
RPS27 | interactor | 41 | 0.804 | 23.586 | Ribosomal_S27e (PF01667, IPR000592): Ribosomal protein S27 DUF3795 (PF12675, IPR024227): Protein of unknown function (DUF3795) |
148 |
RPS27L | interactor | 30 | 0.823 | 13.891 | E7 (PF00527, IPR000148): E7 protein, Early protein Ribosomal_S27e (PF01667, IPR000592): Ribosomal protein S27 zf-C2HC5 (PF06221, IPR009349): Putative zinc finger motif, C2HC5-type DUF3382 (PF11862, IPR021807): Domain of unknown function (DUF3382) |
149 |
RPS3 | interactor | 63 | 0.548 | 241.196 | KH_2 (PF07650, IPR004044): KH domain Ribosomal_S3_C (PF00189, IPR001351): Ribosomal protein S3, C-terminal domain |
150 |
RPS3A | interactor | 59 | 0.667 | 62.595 | Ribosomal_S3Ae (PF01015, IPR001593): Ribosomal S3Ae family |
151 |
RPS5 | interactor | 50 | 0.682 | 74.102 | Ribosomal_S7 (PF00177, IPR023798): Ribosomal protein S7p/S5e |
152 |
RPS6 | interactor | 57 | 0.659 | 94.722 | Ribosomal_S6e (PF01092, IPR001377): Ribosomal protein S6e DUF4574 (PF15141, IPR027896): Domain of unknown function (DUF4574) |
153 |
RPS8 | interactor | 59 | 0.635 | 102.648 | Ribosomal_S8e (PF01201, IPR022309): Ribosomal protein S8e |
154 |
RPS9 | interactor | 54 | 0.693 | 48.860 | Ribosomal_S4 (PF00163, IPR001912): Ribosomal protein S4/S9 N-terminal domain S4 (PF01479, IPR002942, SM00363): S4 domain |
155 |
RPSA | interactor | 60 | 0.579 | 170.763 | Ribosomal_S2 (PF00318, IPR001865): Ribosomal protein S2 40S_SA_C (PF16122, IPR032281): 40S ribosomal protein SA C-terminus |
156 |
SAP25 | interactor | 2 | 1.000 | 0 | SAP25 (PF15476, IPR029163): Histone deacetylase complex subunit SAP25 |
157 |
SAT1 | protein found in more fusions | 5 | 0.500 | 2.667 | Acetyltransf_1 (PF00583, IPR000182): Acetyltransferase (GNAT) family |
158 |
SFN | suppressor | 31 | 0.653 | 59.674 | 14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein |
159 |
SGTB | interactor | 2 | 1.000 | 0 | TOM20_plant (PF06552, IPR010547): Plant specific mitochondrial import receptor subunit TOM20 TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat XPC-binding (PF09280, IPR015360): XPC-binding domain TPR_11 (PF13414, IPR011990): TPR repeat SGTA_dimer (PF16546, IPR032374): Homodimerisation domain of SGTA |
160 |
SIRT7 | interactor | 41 | 0.380 | 178.481 | DUF563 (PF04577, IPR007657): Protein of unknown function (DUF563) SIR2 (PF02146, IPR003000): Sir2 family |
161 |
SKI | oncoprotein | 12 | 0.564 | 6.907 | c-SKI_SMAD_bind (PF08782, IPR014890, SM01046): c-SKI Smad4 binding domain Ski_Sno (PF02437, IPR003380): SKI/SNO/DAC family SlyX (PF04102, IPR007236): SlyX HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1 |
162 |
SLC27A6 | interactor | 2 | 1.000 | 0 | AMP-binding (PF00501, IPR000873): AMP-binding enzyme AMP-binding_C (PF13193, IPR025110): AMP-binding enzyme C-terminal domain |
163 |
SLC9A3R1 | suppressor | 8 | 0.429 | 6.076 | EBP50_C (PF09007, IPR015098): EBP50, C-terminal PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) |
164 |
SRC | oncoprotein | 19 | 0.222 | 88.698 | Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain |
165 |
SREK1 | protein found in more fusions | 8 | 0.857 | 0.200 | Ureide_permease (PF07168, IPR009834): Ureide permease RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RP-C_C (PF11800, IPR021760): Replication protein C C-terminal region PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term DUF3915 (PF13054, IPR025026): Protein of unknown function (DUF3915) BRD4_CDT (PF17105, IPR031354): C-terminal domain of bromodomain protein 4 |
166 |
STAT1 | suppressor | 15 | 0.297 | 44.770 | SH2 (PF00017, IPR000980, SM00252): SH2 domain STAT_alpha (PF01017, IPR013800): STAT protein, all-alpha domain STAT_bind (PF02864, IPR013801): STAT protein, DNA binding domain STAT_int (PF02865, IPR013799, SM00964): STAT protein, protein interaction domain STAT1_TAZ2bind (PF12162, IPR022752): STAT1 TAZ2 binding domain |
167 |
STAU1 | protein found in more fusions | 43 | 0.532 | 109.337 | dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif Staufen_C (PF16482, IPR032478): Staufen C-terminal domain |
168 |
SUZ12 | suppressor | 12 | 0.527 | 10.215 | DUF2070 (PF09843, IPR019204): Predicted membrane protein (DUF2070) VEFS-Box (PF09733, IPR019135): VEFS-Box of polycomb protein |
169 |
SYN2 | interactor | 2 | 0 | 0 | LpxD (PF04613, IPR020573): UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD SPX (PF03105, IPR004331): SPX domain Synapsin_C (PF02750, IPR020898): Synapsin, ATP binding domain Synapsin_N (PF10581, IPR019736): Synapsin N-terminal DUF2076 (PF09849, IPR018648): Uncharacterized protein conserved in bacteria (DUF2076) Synapsin (PF02078, IPR020897): Synapsin, N-terminal domain |
170 |
SYNCRIP | interactor | 35 | 0.387 | 100.872 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 (PF11608, IPR024582): Limkain b1 |
171 |
TARDBP | interactor | 53 | 0.502 | 180.914 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
172 |
TBXA2R | interactor | 6 | 0.500 | 4.500 | 7tm_1 (PF00001, IPR000276): 7 transmembrane receptor (rhodopsin family) |
173 |
TCEB1 | oncoprotein | 15 | 0.381 | 40.991 | Skp1_POZ (PF03931, IPR016073): Skp1 family, tetramerisation domain |
174 |
TCEB2 | interactor | 13 | 0.487 | 20.050 | ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family |
175 |
TIAL1 | interactor | 16 | 0.475 | 17.217 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
176 |
TNFRSF11A | oncoprotein | 4 | 1.000 | 0 | Abi (PF02517, IPR003675): CAAX protease self-immunity DAG1 (PF05454, IPR008465): Dystroglycan (Dystrophin-associated glycoprotein 1) KIX (PF02172, IPR003101): KIX domain TNFR_c6 (PF00020, IPR001368, SM00208): TNFR/NGFR cysteine-rich region |
177 |
TNRC6C | interactor | 4 | 1.000 | 0 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain Ago_hook (PF10427, IPR019486): Argonaute hook DUF3439 (PF11921, IPR024592): Domain of unknown function (DUF3439) M_domain (PF12938, IPR026805): M domain of GW182 DUF4718 (PF15842, IPR031695): Domain of unknown function (DUF4718) TNRC6-PABC_bdg (PF16608, IPR032226): TNRC6-PABC binding domain |
178 |
TP53BP1 | suppressor | 10 | 0.422 | 13.084 | 53-BP1_Tudor (PF09038, IPR015125): Tumour suppressor p53-binding protein-1 Tudor BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain FXMRP1_C_core (PF12235, IPR022034): Fragile X-related 1 protein core C terminal DUF4772 (PF15997, IPR031940): Domain of unknown function (DUF4772) BRCT_2 (PF16589, IPR001357): BRCT domain, a BRCA1 C-terminus domain |
179 |
TP63 | suppressor | 11 | 0.444 | 7.086 | Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region P53 (PF00870, IPR011615): P53 DNA-binding domain P53_tetramer (PF07710, IPR010991): P53 tetramerisation motif SAM_2 (PF07647, IPR011510): SAM domain (Sterile alpha motif) |
180 |
TP73 | suppressor | 9 | 0.536 | 4.405 | P53 (PF00870, IPR011615): P53 DNA-binding domain P53_tetramer (PF07710, IPR010991): P53 tetramerisation motif SAM_2 (PF07647, IPR011510): SAM domain (Sterile alpha motif) |
181 |
TRAF2 | interactor | 12 | 0.345 | 25.316 | MATH (PF00917, IPR002083, SM00061): MATH domain Sina (PF03145, IPR018121): Seven in absentia protein family SlyX (PF04102, IPR007236): SlyX zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger) zf-TRAF (PF02176, IPR001293): TRAF-type zinc finger TRAF_BIRC3_bd (PF16673, IPR032070): TNF receptor-associated factor BIRC3 binding domain zf-C3HC4_5 (PF17121, IPR001841): Zinc finger, C3HC4 type (RING finger) |
182 |
TRAF6 | protein found in more fusions | 12 | 0.382 | 25.618 | SlyX (PF04102, IPR007236): SlyX zf-TRAF (PF02176, IPR001293): TRAF-type zinc finger zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger) |
183 |
TRIM45 | interactor | 3 | 1.000 | 0 | ATP-synt_ab_C (PF00306, IPR000793): ATP synthase alpha/beta chain, C terminal domain Filamin (PF00630, IPR017868): Filamin/ABP280 repeat zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger Prok-RING_4 (PF14447): Prokaryotic RING finger family 4 HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1 |
184 |
TSC22D4 | interactor | 6 | 0.333 | 6.125 | AflR (PF08493, IPR013700): Aflatoxin regulatory protein TSC22 (PF01166, IPR000580): TSC-22/dip/bun family |
185 |
TYK2 | interactor | 7 | 0.400 | 6.500 | Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase |
186 |
U2AF2 | protein found in more fusions | 37 | 0.375 | 154.858 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Transformer (PF06495, IPR010519): Fruit fly transformer protein |
187 |
UBE2T | interactor | 3 | 1.000 | 0 | UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme |
188 |
UBL4A | interactor | 44 | 0.543 | 170.182 | ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family |
189 |
UNK | interactor | 13 | 0.359 | 15.468 | MbeD_MobD (PF04899, IPR006983): MbeD/MobD like NUDE_C (PF04880, IPR006964): NUDE protein, C-terminal conserved region zf-CCCH (PF00642, IPR000571): Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF3450 (PF11932, IPR016866): Protein of unknown function (DUF3450) zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger) zf-CCCH_2 (PF14608): RNA-binding, Nab2-type zinc finger Torus (PF16131, IPR032297): Torus domain |
190 |
VCAM1 | interactor | 48 | 0.494 | 121.175 | C2-set (PF05790, IPR008424): Immunoglobulin C2-set domain I-set (PF07679, IPR013098): Immunoglobulin I-set domain ig (PF00047, IPR013151, SM00409): Immunoglobulin domain V-set (PF07686, IPR013106): Immunoglobulin V-set domain Ig_3 (PF13927): Immunoglobulin domain |
191 |
VHL | suppressor | 33 | 0.440 | 128.217 | Trypan_PARP (PF05887, IPR008882): Procyclic acidic repetitive protein (PARP) VHL (PF01847, IPR022772): von Hippel-Lindau disease tumour suppressor protein VHL_C (PF17211): VHL box domain |
192 |
WDR76 | interactor | 7 | 0.571 | 3.230 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat SPATIAL (PF15256): SPATIAL |
193 |
WDR83 | interactor | 3 | 0.667 | 0.143 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain |
194 |
WIPI1 | interactor | 3 | 0.667 | 0.250 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat BCAS3 (PF12490, IPR022175): Breast carcinoma amplified sequence 3 ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain |
195 |
ZCCHC3 | interactor | 9 | 0.500 | 6.619 | zf-CCHC (PF00098, IPR001878): Zinc knuckle zf-CCHC_2 (PF13696, IPR025829): Zinc knuckle |