1 |
PUF60 | parental protein | 123 | 0.124 | 7147.185 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Titin_Z (PF09042, IPR015129): Titin Z TAT_signal (PF10518, IPR019546): TAT (twin-arginine translocation) pathway signal sequence |
2 |
ABCC1 | oncoprotein | 5 | 1.000 | 0 | ABC_membrane (PF00664, IPR001140): ABC transporter transmembrane region ABC_tran (PF00005, IPR003439): ABC transporter SMC_N (PF02463, IPR003395): RecF/RecN/SMC N terminal domain ABC_ATPase (PF09818, IPR019195): Predicted ATPase of the ABC class DUF2304 (PF10066, IPR019277): Uncharacterized conserved protein (DUF2304) DUF4131 (PF13567, IPR025405): Domain of unknown function (DUF4131) |
3 |
AIMP2 | suppressor | 8 | 0.524 | 4.309 | GST_C_2 (PF13410): Glutathione S-transferase, C-terminal domain GST_C_3 (PF14497, IPR004046): Glutathione S-transferase, C-terminal domain AIMP2_LysRS_bd (PF16780, IPR031889): AIMP2 lysyl-tRNA synthetase binding domain |
4 |
ARGLU1 | interactor | 9 | 0.464 | 2.347 | eIF3_subunit (PF08597, IPR013906): Translation initiation factor eIF3 subunit Kri1 (PF05178, IPR018034): KRI1-like family ARGLU (PF15346): Arginine and glutamate-rich 1 |
5 |
ARL8A | interactor | 1 | 0 | 0 | Arf (PF00025, IPR006689, SM00177): ADP-ribosylation factor family |
6 |
AXIN1 | suppressor | 3 | 1.000 | 0 | Axin_b-cat_bind (PF08833, IPR014936): Axin beta-catenin binding domain RGS (PF00615, IPR000342, SM00315): Regulator of G protein signaling domain DIX (PF00778, IPR001158, SM00021): DIX domain AXIN1_TNKS_BD (PF16646, IPR032101): Axin-1 tankyrase binding domain |
7 |
BARD1 | suppressor | 18 | 0.324 | 38.181 | BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_5 (PF13857): Ankyrin repeats (many copies) zf-RING_6 (PF14835): zf-RING of BARD1-type protein BRCT_2 (PF16589, IPR001357): BRCT domain, a BRCA1 C-terminus domain |
8 |
BORCS5 | interactor | 1 | 0 | 0 | LOH1CR12 (PF10158, IPR018780): Tumour suppressor protein |
9 |
CACNA1A | interactor | 1 | 0 | 0 | Ca_chan_IQ (PF08763, IPR014873, SM01062): Voltage gated calcium channel IQ domain GRP (PF07172, IPR010800): Glycine rich protein family Ion_trans (PF00520, IPR005821): Ion transport protein Roughex (PF06020, IPR009259): Drosophila roughex protein SelP_N (PF04592, IPR007671): Selenoprotein P, N terminal region GPHH (PF16905, IPR031649): Voltage-dependent L-type calcium channel, IQ-associated |
10 |
CAND1 | interactor | 50 | 0.344 | 245.573 | Adaptin_N (PF01602, IPR002553): Adaptin N terminal region DUF1981 (PF09324, IPR015403): Domain of unknown function (DUF1981) HEAT (PF02985, IPR000357): HEAT repeat TIP120 (PF08623, IPR013932): TATA-binding protein interacting (TIP20) RTP1_C1 (PF10363, IPR019451): Required for nuclear transport of RNA pol II C-terminus 1 DUF3385 (PF11865, IPR024585): Domain of unknown function (DUF3385) MMS19_C (PF12460, IPR024687): RNAPII transcription regulator C-terminal Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region HEAT_EZ (PF13513): HEAT-like repeat HEAT_2 (PF13646): HEAT repeats MMS19_N (PF14500): Dos2-interacting transcription regulator of RNA-Pol-II |
11 |
CCNC | suppressor | 4 | 0.667 | 1.667 | Cyclin_C (PF02984, IPR004367): Cyclin, C-terminal domain Cyclin_N (PF00134, IPR006671): Cyclin, N-terminal domain Cyclin_C_2 (PF16899, IPR031658): Cyclin C-terminal domain |
12 |
CD2BP2 | interactor | 9 | 0.556 | 5.693 | GYF (PF02213, IPR003169, SM00444): GYF domain EF-1_beta_acid (PF10587, IPR018940): Eukaryotic elongation factor 1 beta central acidic region Hist_rich_Ca-bd (PF10529, IPR019552): Histidine-rich Calcium-binding repeat region |
13 |
CDK2 | suppressor | 37 | 0.284 | 212.330 | Kdo (PF06293, IPR010440): Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase (PF00069, IPR000719): Protein kinase domain |
14 |
CDKN1A | suppressor | 9 | 0.306 | 11.039 | CDI (PF02234, IPR003175): Cyclin-dependent kinase inhibitor |
15 |
CHD3 | oncoprotein | 11 | 0.356 | 12.362 | CHDCT2 (PF08074, IPR012957): CHDCT2 (NUC038) domain CHDNT (PF08073, IPR012958): CHDNT (NUC034) domain Chromo (PF00385, IPR023780, SM00298): Chromo (CHRromatin Organisation MOdifier) domain DUF1086 (PF06461, IPR009462, SM01146): Domain of Unknown Function (DUF1086) DUF1087 (PF06465, IPR009463, SM01147): Domain of Unknown Function (DUF1087) DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777) Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator FYDLN_acid (PF09538, IPR012644): Protein of unknown function (FYDLN_acid) PHD (PF00628, IPR019787, SM00249): PHD-finger Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein SMN (PF06003, IPR010304): Survival motor neuron protein (SMN) SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain DUF2956 (PF11169, IPR021339): Protein of unknown function (DUF2956) FAM176 (PF14851): FAM176 family |
16 |
COPS5 | protein found in more fusions | 45 | 0.340 | 181.680 | JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease |
17 |
CPSF6 | interactor | 18 | 0.542 | 18.550 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term PRIMA1 (PF16101): Proline-rich membrane anchor 1 |
18 |
CUL3 | protein found in more fusions | 54 | 0.286 | 363.263 | Cullin (PF00888, IPR001373, SM00182): Cullin family Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain WAC_Acf1_DNA_bd (PF10537, IPR013136): ATP-utilising chromatin assembly and remodelling N-terminal |
19 |
CUL7 | protein found in more fusions | 47 | 0.272 | 238.331 | ANAPC10 (PF03256, IPR004939): Anaphase-promoting complex, subunit 10 (APC10) Cullin (PF00888, IPR001373, SM00182): Cullin family DUF1918 (PF08940, IPR015035): Domain of unknown function (DUF1918) Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain Cul7 (PF11515, IPR021097): Mouse development and cellular proliferation protein Cullin-7 |
20 |
DDB1 | protein found in more fusions | 18 | 0.397 | 35.789 | CPSF_A (PF03178, IPR004871): CPSF A subunit region MMS1_N (PF10433): Mono-functional DNA-alkylating methyl methanesulfonate N-term |
21 |
DDX3X | suppressor | 20 | 0.516 | 16.587 | DEAD (PF00270, IPR011545): DEAD/DEAH box helicase DUF755 (PF05501, IPR008474): Domain of unknown function (DUF755) Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain |
22 |
EED | suppressor | 29 | 0.317 | 61.034 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160 ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain |
23 |
EEF1A1 | suppressor | 31 | 0.411 | 116.798 | GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2 GTP_EFTU_D3 (PF03143, IPR004160): Elongation factor Tu C-terminal domain |
24 |
EIF4H | interactor | 9 | 0.667 | 1.446 | eIF-4B (PF06273, IPR010433): Plant specific eukaryotic initiation factor 4B RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
25 |
ELAC2 | oncoprotein | 4 | 1.000 | 0 | Synthase_beta (PF11421, IPR020971): ATP synthase F1 beta subunit Lactamase_B_2 (PF12706, IPR001279): Beta-lactamase superfamily domain Lactamase_B_4 (PF13691, IPR027794): tRNase Z endonuclease |
26 |
ERG | oncoprotein | 14 | 0.527 | 5.884 | Ets (PF00178, IPR000418, SM00413): Ets-domain SAM_2 (PF07647, IPR011510): SAM domain (Sterile alpha motif) SAM_PNT (PF02198, IPR003118, SM00251): Sterile alpha motif (SAM)/Pointed domain |
27 |
EWSR1 | oncoprotein | 37 | 0.329 | 173.519 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SVS_QK (PF10578, IPR018942): Seminal vesicle protein repeat zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 Keratin_2_head (PF16208, IPR032444): Keratin type II head |
28 |
FAF1 | protein found in more fusions | 11 | 0.533 | 11.950 | UBX (PF00789, IPR001012, SM00166): UBX domain ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family AAA_11 (PF13086): AAA domain UBA_4 (PF14555): UBA-like domain |
29 |
FAM129B | interactor | 9 | 0.611 | 6.671 | PH (PF00169, IPR001849, SM00233): PH domain |
30 |
FBXW7 | suppressor | 9 | 0.393 | 9.974 | Mem_trans (PF03547, IPR004776): Membrane transport protein WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160 F-box-like (PF12937, IPR001810): F-box-like |
31 |
FHL2 | oncoprotein | 6 | 0.500 | 3.167 | LIM (PF00412, IPR001781, SM00132): LIM domain zf-ribbon_3 (PF13248): zinc-ribbon domain |
32 |
FN1 | oncoprotein | 42 | 0.240 | 218.221 | fn1 (PF00039, IPR000083, SM00058): Fibronectin type I domain fn2 (PF00040, IPR000562, SM00059): Fibronectin type II domain fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369) |
33 |
FOXK2 | interactor | 4 | 0.667 | 0.582 | FHA (PF00498, IPR000253, SM00240): FHA domain Forkhead (PF00250, IPR001766, SM00339): Forkhead domain |
34 |
FOXL1 | oncoprotein | 4 | 0.500 | 1.900 | Forkhead (PF00250, IPR001766, SM00339): Forkhead domain |
35 |
FOXL2 | suppressor | 4 | 0.500 | 1.286 | K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain Forkhead (PF00250, IPR001766, SM00339): Forkhead domain PRIMA1 (PF16101): Proline-rich membrane anchor 1 |
36 |
FOXQ1 | interactor | 4 | 0.667 | 0.508 | Forkhead (PF00250, IPR001766, SM00339): Forkhead domain |
37 |
G3BP1 | protein found in more fusions | 14 | 0.628 | 9.816 | NTF2 (PF02136, IPR002075): Nuclear transport factor 2 (NTF2) domain RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3306 (PF11748, IPR021735): Protein of unknown function (DUF3306) PTPRCAP (PF15713, IPR016553): Protein tyrosine phosphatase receptor type C-associated |
38 |
GPN1 | interactor | 3 | 1.000 | 0 | ATP_bind_1 (PF03029, IPR004130): Conserved hypothetical ATP binding protein NB-ARC (PF00931, IPR002182): NB-ARC domain |
39 |
H3F3A | oncoprotein | 8 | 0.429 | 8.344 | Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4 |
40 |
HDAC6 | oncoprotein | 9 | 0.429 | 8.795 | Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain PSGP (PF07276, IPR009900): Apopolysialoglycoprotein (PSGP) zf-UBP (PF02148, IPR001607, SM00290): Zn-finger in ubiquitin-hydrolases and other protein |
41 |
HIRIP3 | interactor | 5 | 1.000 | 0 | CHZ (PF09649, IPR019098, SM01082): Histone chaperone domain CHZ |
42 |
HIST1H1C | oncoprotein | 8 | 0.714 | 0.942 | Amelin (PF05111, IPR007798, SM00817): Ameloblastin precursor (Amelin) Linker_histone (PF00538, IPR005818, SM00526): linker histone H1 and H5 family DUF4349 (PF14257, IPR025645): Domain of unknown function (DUF4349) |
43 |
HNRNPA1 | interactor | 48 | 0.387 | 222.942 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HnRNPA1 (PF11627, IPR021662): Nuclear factor hnRNPA1 |
44 |
HNRNPA3 | oncoprotein | 23 | 0.636 | 13.750 | IATP (PF04568, IPR007648): Mitochondrial ATPase inhibitor, IATP RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 |
45 |
HNRNPC | protein found in more fusions | 30 | 0.424 | 74.693 | APG6 (PF04111, IPR007243): Autophagy protein Apg6 RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SURF2 (PF05477, IPR008833): Surfeit locus protein 2 (SURF2) |
46 |
HNRNPF | interactor | 26 | 0.505 | 42.100 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Spot_14 (PF07084, IPR009786): Thyroid hormone-inducible hepatic protein Spot 14 zf-RNPHF (PF08080, IPR012996): RNPHF zinc finger |
47 |
HNRNPH3 | protein found in more fusions | 19 | 0.654 | 7.498 | Herpes_PAP (PF03325, IPR004997): Herpesvirus polymerase accessory protein RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
48 |
HNRNPL | protein found in more fusions | 22 | 0.595 | 33.385 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Dscam_C (PF12355, IPR021012): Down syndrome cell adhesion molecule C terminal RRM_5 (PF13893): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
49 |
HNRNPM | interactor | 33 | 0.451 | 91.044 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HnRNP_M (PF11532, IPR024666): Heterogeneous nuclear ribonucleoprotein M Collagen_mid (PF15984, IPR031929): Bacterial collagen, middle region |
50 |
HSPD1 | suppressor | 21 | 0.476 | 22.300 | Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family |
51 |
ID3 | oncoprotein | 4 | 0.667 | 0.500 | HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain |
52 |
IGF2BP1 | oncoprotein | 15 | 0.505 | 19.764 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) KH_1 (PF00013, IPR004088, SM00322): KH domain KH_4 (PF13083): KH domain MOEP19 (PF16005, IPR031952): KH-like RNA-binding domain |
53 |
IGF2BP2 | interactor | 8 | 0.714 | 1.113 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) KH_1 (PF00013, IPR004088, SM00322): KH domain KH_4 (PF13083): KH domain |
54 |
IGF2BP3 | interactor | 17 | 0.610 | 12.548 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) KH_1 (PF00013, IPR004088, SM00322): KH domain KH_4 (PF13083): KH domain |
55 |
ILF2 | interactor | 33 | 0.462 | 88.480 | DZF (PF07528, IPR006561, SM00572): DZF domain |
56 |
ILK | suppressor | 15 | 0.495 | 13.793 | Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_4 (PF13637): Ankyrin repeats (many copies) Ank_5 (PF13857): Ankyrin repeats (many copies) |
57 |
KHSRP | interactor | 17 | 0.478 | 16.474 | DUF1897 (PF09005, IPR015096): Domain of unknown function (DUF1897) KH_1 (PF00013, IPR004088, SM00322): KH domain |
58 |
KIAA0907 | interactor | 4 | 0.667 | 0.258 | NA |
59 |
KIAA1683 | interactor | 2 | 1.000 | 0 | IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif |
60 |
KLC4 | interactor | 4 | 0.667 | 0.554 | Flagellin_N (PF00669, IPR001029): Bacterial flagellin N-terminal helical region Uso1_p115_C (PF04871, IPR006955): Uso1 / p115 like vesicle tethering protein, C terminal region TPR_10 (PF13374, IPR011990): Tetratricopeptide repeat TPR_12 (PF13424): Tetratricopeptide repeat LUD_dom (PF02589): LUD domain |
61 |
LAMTOR3 | interactor | 6 | 0.467 | 5.900 | MAPKK1_Int (PF08923, IPR015019): Mitogen-activated protein kinase kinase 1 interacting |
62 |
MATR3 | interactor | 29 | 0.516 | 61.227 | DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777) RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-U1 (PF06220, IPR013085, SM00451): U1 zinc finger Tim54 (PF11711, IPR021056): Inner membrane protein import complex subunit Tim54 zf-C2H2_jaz (PF12171, IPR022755): Zinc-finger double-stranded RNA-binding RRM_5 (PF13893): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FAM60A (PF15396, IPR026065): Protein Family FAM60A |
63 |
MCM2 | oncoprotein | 40 | 0.296 | 236.625 | AAA_3 (PF07726, IPR011703): ATPase family associated with various cellular activities (AAA) MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family MCM2_N (PF12619, IPR008045): Mini-chromosome maintenance protein 2 MCM_N (PF14551, IPR027925): MCM N-terminal domain MCM_OB (PF17207): MCM OB domain |
64 |
MED28 | interactor | 6 | 0.600 | 2.833 | cwf21 (PF08312, IPR013170, SM01115): cwf21 domain Med28 (PF11594, IPR021640): Mediator complex subunit 28 |
65 |
MOV10 | interactor | 34 | 0.203 | 297.191 | AAA_12 (PF13087): AAA domain AAA_30 (PF13604): AAA domain |
66 |
MPV17 | interactor | 4 | 0.667 | 1.200 | Mpv17_PMP22 (PF04117, IPR007248): Mpv17 / PMP22 family |
67 |
MRM3 | interactor | 3 | 0.667 | 0.500 | SpoU_methylase (PF00588, IPR001537): SpoU rRNA Methylase family SpoU_sub_bind (PF08032, IPR013123, SM00967): RNA 2'-O ribose methyltransferase substrate binding |
68 |
MYO18A | interactor | 3 | 0.667 | 0.133 | Vfa1 (PF08432, IPR013640): AAA-ATPase Vps4-associated protein 1 IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif Myosin_tail_1 (PF01576, IPR002928): Myosin tail PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein CENP-F_leu_zip (PF10473, IPR019513): Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain) BST2 (PF16716, IPR024886): Bone marrow stromal antigen 2 |
69 |
NTRK1 | oncoprotein | 73 | 0.198 | 1101.785 | I-set (PF07679, IPR013098): Immunoglobulin I-set domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase LRR_8 (PF13855, IPR001611): Leucine rich repeat TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain |
70 |
NUDC | interactor | 12 | 0.485 | 16.834 | CS (PF04969, IPR007052): CS domain D5_N (PF08706, IPR014818, SM00885): D5 N terminal like Vfa1 (PF08432, IPR013640): AAA-ATPase Vps4-associated protein 1 Nudc_N (PF14050, IPR025934): N-terminal conserved domain of Nudc. NuDC (PF16273, IPR032572): Nuclear distribution C domain |
71 |
OBSL1 | interactor | 38 | 0.377 | 85.557 | BiPBP_C (PF06832, IPR009647): Penicillin-Binding Protein C-terminus Family fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain Herpes_gE (PF02480, IPR003404): Alphaherpesvirus glycoprotein E I-set (PF07679, IPR013098): Immunoglobulin I-set domain V-set (PF07686, IPR013106): Immunoglobulin V-set domain Ig_3 (PF13927): Immunoglobulin domain Ig_4 (PF16680, IPR032052): T-cell surface glycoprotein CD3 delta chain Izumo-Ig (PF16706, IPR032699): Izumo-like Immunoglobulin domain |
72 |
OLA1 | interactor | 9 | 0.444 | 7.315 | Roc (PF08477, IPR013684): Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 (PF01926, IPR006073): 50S ribosome-binding GTPase YchF-GTPase_C (PF06071, IPR013029): Protein of unknown function (DUF933) |
73 |
P4HB | interactor | 15 | 0.615 | 8.357 | Glycos_trans_3N (PF02885, IPR017459): Glycosyl transferase family, helical bundle domain Thioredoxin (PF00085, IPR013766): Thioredoxin Thioredoxin_6 (PF13848): Thioredoxin-like domain |
74 |
PABPC1 | oncoprotein | 23 | 0.550 | 24.532 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP (PF00658, IPR002004, SM00517): Poly-adenylate binding protein, unique domain YflT (PF11181, IPR025889): Heat induced stress protein YflT |
75 |
PABPC4 | interactor | 18 | 0.627 | 9.619 | ApbA_C (PF08546, IPR013752): Ketopantoate reductase PanE/ApbA C terminal RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP (PF00658, IPR002004, SM00517): Poly-adenylate binding protein, unique domain HHV-5_US34A (PF17087, IPR031384): Herpesvirus US34A protein family |
76 |
PAPOLA | interactor | 10 | 0.600 | 6.737 | PAP_central (PF04928, IPR007012): Poly(A) polymerase central domain PAP_RNA-bind (PF04926, IPR007010): Poly(A) polymerase predicted RNA binding domain Macoilin (PF09726, IPR019130): Transmembrane protein |
77 |
PCBP1 | oncoprotein | 18 | 0.497 | 15.927 | Bac_chlorC (PF02043, IPR001470): Bacteriochlorophyll C binding protein KH_2 (PF07650, IPR004044): KH domain KH_1 (PF00013, IPR004088, SM00322): KH domain |
78 |
PPM1G | interactor | 11 | 0.436 | 20.123 | Cwf_Cwc_15 (PF04889, IPR006973): Cwf15/Cwc15 cell cycle control protein DUF1510 (PF07423, IPR009988): Protein of unknown function (DUF1510) PP2C (PF00481, IPR001932): Protein phosphatase 2C DUF4820 (PF16091, IPR032150): Domain of unknown function (DUF4820) |
79 |
PPP1R16A | interactor | 2 | 0 | 0 | Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_4 (PF13637): Ankyrin repeats (many copies) Ank_5 (PF13857): Ankyrin repeats (many copies) |
80 |
PRPF40A | protein found in more fusions | 30 | 0.463 | 70.615 | FF (PF01846, IPR002713, SM00441): FF domain MCR_alpha (PF02249, IPR009047): Methyl-coenzyme M reductase alpha subunit, C-terminal domain Transformer (PF06495, IPR010519): Fruit fly transformer protein WW (PF00397, IPR001202, SM00456): WW domain YqzE (PF14038, IPR025622): YqzE-like protein SPT6_acidic (PF14632, IPR028083): Acidic N-terminal SPT6 SRRM_C (PF15230, IPR029360): Serine/arginine repetitive matrix protein C-terminus SOBP (PF15279, IPR026092): Sine oculis-binding protein IHABP4_N (PF16174, IPR032381): Intracellular hyaluronan-binding protein 4 N-terminal |
81 |
PSMA3 | interactor | 14 | 0.397 | 15.690 | Proteasome (PF00227, IPR001353): Proteasome subunit Proteasome_A_N (PF10584, IPR000426, SM00948): Proteasome subunit A N-terminal signature |
82 |
PTBP2 | interactor | 5 | 0.667 | 0.287 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 (PF13893): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
83 |
QRICH1 | interactor | 5 | 0.667 | 1.167 | CARD (PF00619, IPR001315, SM00114): Caspase recruitment domain Pex14_N (PF04695, IPR006785): Peroxisomal membrane anchor protein (Pex14p) conserved region PAT1 (PF09770, IPR019167): Topoisomerase II-associated protein PAT1 DUF3504 (PF12012, IPR021893): Domain of unknown function (DUF3504) RBM39linker (PF15519, IPR029123): linker between RRM2 and RRM3 domains in RBM39 protein |
84 |
RAB2A | oncoprotein | 6 | 0.400 | 4.825 | Ras (PF00071, IPR001806, SM00173): Ras family |
85 |
RAD23B | suppressor | 10 | 0.400 | 13.382 | K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain XPC-binding (PF09280, IPR015360): XPC-binding domain ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family DUF3123 (PF11321, IPR021470): Protein of unknown function (DUF3123) |
86 |
RAP1GDS1 | oncoprotein | 5 | 0.700 | 1.033 | Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat WAPL (PF07814, IPR022771): Wings apart-like protein regulation of heterochromatin Vps39_1 (PF10366, IPR019452): Vacuolar sorting protein 39 domain 1 V-ATPase_H_C (PF11698, IPR011987): V-ATPase subunit H HEAT_2 (PF13646): HEAT repeats Nitr_red_bet_C (PF14711, IPR029263): Respiratory nitrate reductase beta C-terminal SIL1 (PF16782, IPR031884): Nucleotide exchange factor SIL1 |
87 |
RBM25 | interactor | 16 | 0.500 | 15.092 | Vfa1 (PF08432, IPR013640): AAA-ATPase Vps4-associated protein 1 PWI (PF01480, IPR002483, SM00311): PWI domain RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SMN (PF06003, IPR010304): Survival motor neuron protein (SMN) SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal MIP-T3 (PF10243): Microtubule-binding protein MIP-T3 DUF3441 (PF11923, IPR021846): Domain of unknown function (DUF3441) U1snRNP70_N (PF12220, IPR022023): U1 small nuclear ribonucleoprotein of 70kDa MW N terminal DUF4778 (PF16008, IPR031958): Domain of unknown function (DUF4778) |
88 |
RNPS1 | interactor | 24 | 0.507 | 40.739 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2457 (PF10446, IPR018853): Protein of unknown function (DUF2457) Macoilin (PF09726, IPR019130): Transmembrane protein |
89 |
RPL6 | protein found in more fusions | 21 | 0.667 | 9.504 | Ribosomal_L6e (PF01159, IPR000915): Ribosomal protein L6e Ribosomal_L6e_N (PF03868, IPR005568): Ribosomal protein L6, N-terminal domain |
90 |
SAP30BP | interactor | 9 | 0.528 | 7.265 | Dicty_REP (PF05086, IPR007778): Dictyostelium (Slime Mold) REP protein HCNGP (PF07818, IPR012479): HCNGP-like protein Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal |
91 |
SARS2 | interactor | 6 | 0.867 | 0.536 | tRNA-synt_2b (PF00587, IPR002314): tRNA synthetase class II core domain (G, H, P, S and T) DUF2312 (PF10073, IPR018753): Uncharacterized protein conserved in bacteria (DUF2312) DUF4445 (PF14574, IPR027980): Domain of unknown function (DUF4445) |
92 |
SDCBP | interactor | 7 | 0.381 | 5.833 | PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) |
93 |
SF3A2 | interactor | 24 | 0.442 | 43.878 | Cytadhesin_P30 (PF07271, IPR009896): Cytadhesin P30/P32 PRP4 (PF08799, IPR014906): pre-mRNA processing factor 4 (PRP4) like Totivirus_coat (PF05518, IPR008871): Totivirus coat protein zf-met (PF12874): Zinc-finger of C2H2 type ARL6IP6 (PF15062, IPR029383): Haemopoietic lineage transmembrane helix SF3A2 (PF16835, IPR031781): Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) |
94 |
SF3A3 | interactor | 21 | 0.405 | 43.327 | DUF3449 (PF11931, IPR024598): Domain of unknown function (DUF3449) SF3a60_bindingd (PF12108, IPR021966): Splicing factor SF3a60 binding domain Telomere_Sde2_2 (PF13297): Telomere stability C-terminal PBP1_TM (PF14812, IPR032730): Transmembrane domain of transglycosylase PBP1 at N-terminal SF3A3 (PF16837, IPR031774): Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 |
95 |
SF3B1 | oncoprotein | 27 | 0.427 | 90.933 | Dopey_N (PF04118, IPR007249): Dopey, N-terminal HEAT (PF02985, IPR000357): HEAT repeat SF3b1 (PF08920, IPR015016): Splicing factor 3B subunit 1 UNC45-central (PF11701, IPR024660): Myosin-binding striated muscle assembly central Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region HEAT_EZ (PF13513): HEAT-like repeat HEAT_2 (PF13646): HEAT repeats |
96 |
SF3B6 | interactor | 13 | 0.603 | 5.879 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
97 |
SIAH1 | suppressor | 8 | 0.286 | 10.174 | Sina (PF03145, IPR018121): Seven in absentia protein family |
98 |
SIRT7 | interactor | 28 | 0.347 | 67.087 | DUF563 (PF04577, IPR007657): Protein of unknown function (DUF563) SIR2 (PF02146, IPR003000): Sir2 family |
99 |
SNRPF | interactor | 15 | 0.343 | 27.214 | LSM (PF01423, IPR001163): LSM domain |
100 |
SNW1 | protein found in more fusions | 35 | 0.396 | 113.729 | SKIP_SNW (PF02731, IPR004015): SKIP/SNW domain PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term SIR4_SID (PF16991, IPR031556): Sir4 SID domain |
101 |
SON | interactor | 14 | 0.659 | 5.978 | Asp-B-Hydro_N (PF05279, IPR007943): Aspartyl beta-hydroxylase N-terminal region G-patch (PF01585, IPR000467, SM00443): G-patch domain tRNA_synt_1c_R2 (PF04557, IPR007638): Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 Eapp_C (PF10238, IPR019370): E2F-associated phosphoprotein DND1_DSRM (PF14709): double strand RNA binding domain from DEAD END PROTEIN 1 GREB1 (PF15782, IPR028422): Gene regulated by oestrogen in breast cancer RSRP (PF17069): Arginine/Serine-Rich protein 1 |
102 |
SREK1 | protein found in more fusions | 15 | 0.429 | 10.206 | Ureide_permease (PF07168, IPR009834): Ureide permease RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RP-C_C (PF11800, IPR021760): Replication protein C C-terminal region PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term DUF3915 (PF13054, IPR025026): Protein of unknown function (DUF3915) BRD4_CDT (PF17105, IPR031354): C-terminal domain of bromodomain protein 4 |
103 |
SRRM1 | interactor | 21 | 0.562 | 19.456 | DUF1754 (PF08555, IPR013865): Eukaryotic family of unknown function (DUF1754) ETRAMP (PF09716, IPR006389): Malarial early transcribed membrane protein (ETRAMP) Hepatitis_core (PF00906, IPR002006): Hepatitis core antigen MAP65_ASE1 (PF03999, IPR007145): Microtubule associated protein (MAP65/ASE1 family) PWI (PF01480, IPR002483, SM00311): PWI domain Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein |
104 |
SRRM2 | interactor | 40 | 0.449 | 116.166 | cwf21 (PF08312, IPR013170, SM01115): cwf21 domain DUF1754 (PF08555, IPR013865): Eukaryotic family of unknown function (DUF1754) Pap_E4 (PF02711, IPR003861): E4 protein RR_TM4-6 (PF06459, IPR009460): Ryanodine Receptor TM 4-6 CTD (PF12815, IPR024945, SM01104): Spt5 C-terminal nonapeptide repeat binding Spt4 DUF4614 (PF15391, IPR027884): Domain of unknown function (DUF4614) |
105 |
SRSF11 | interactor | 18 | 0.503 | 25.403 | Rtf2 (PF04641, IPR027799): Rtf2 RING-finger RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TP2 (PF01254, IPR000678): Nuclear transition protein 2 Transformer (PF06495, IPR010519): Fruit fly transformer protein FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 |
106 |
SSB | interactor | 14 | 0.527 | 12.064 | HMA (PF00403, IPR006121): Heavy-metal-associated domain La (PF05383, IPR006630, SM00715): La domain Prothymosin (PF03247, IPR004931): Prothymosin/parathymosin family Ribosomal_L6e (PF01159, IPR000915): Ribosomal protein L6e RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 (PF08777, IPR014886): RNA binding motif |
107 |
STOM | protein found in more fusions | 6 | 0.500 | 3.400 | Band_7 (PF01145, IPR001107, SM00244): SPFH domain / Band 7 family |
108 |
SYNCRIP | interactor | 26 | 0.597 | 23.206 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 (PF11608, IPR024582): Limkain b1 |
109 |
TADA2A | interactor | 15 | 0.362 | 27.383 | SWIRM (PF04433, IPR007526): SWIRM domain Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain |
110 |
TARS | interactor | 13 | 0.462 | 16.111 | HGTP_anticodon (PF03129, IPR004154): Anticodon binding domain TGS (PF02824, IPR004095): TGS domain tRNA-synt_2b (PF00587, IPR002314): tRNA synthetase class II core domain (G, H, P, S and T) tRNA_SAD (PF07973, IPR012947, SM00863): Threonyl and Alanyl tRNA synthetase second additional domain |
111 |
THRAP3 | oncoprotein | 17 | 0.390 | 39.300 | API5 (PF05918, IPR008383): Apoptosis inhibitory protein 5 (API5) FXMRP1_C_core (PF12235, IPR022034): Fragile X-related 1 protein core C terminal DUF4228 (PF14009, IPR025322): Domain of unknown function (DUF4228) THRAP3_BCLAF1 (PF15440, IPR029199): THRAP3/BCLAF1 family |
112 |
TROVE2 | interactor | 8 | 0.714 | 4.019 | TROVE (PF05731, IPR008858): TROVE domain DUF2201 (PF09967, IPR018698): VWA-like domain (DUF2201) |
113 |
TTN | interactor | 10 | 0.578 | 6.895 | DUF11 (PF01345, IPR001434): Domain of unknown function DUF11 fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region I-set (PF07679, IPR013098): Immunoglobulin I-set domain Pkinase (PF00069, IPR000719): Protein kinase domain PPAK (PF02818, IPR004168): PPAK motif Titin_Z (PF09042, IPR015129): Titin Z V-set (PF07686, IPR013106): Immunoglobulin V-set domain Y_Y_Y (PF07495, IPR011123): Y_Y_Y domain DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369) Ig_3 (PF13927): Immunoglobulin domain |
114 |
U2AF2 | protein found in more fusions | 47 | 0.414 | 183.292 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Transformer (PF06495, IPR010519): Fruit fly transformer protein |
115 |
UBE2I | interactor | 12 | 0.436 | 16.339 | UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme |
116 |
UGP2 | protein found in more fusions | 15 | 0.440 | 29.776 | UDPGP (PF01704, IPR002618): UTP--glucose-1-phosphate uridylyltransferase |
117 |
UPF2 | interactor | 4 | 0.667 | 0.100 | DDHD (PF02862, IPR004177, SM01127): DDHD domain DUF1510 (PF07423, IPR009988): Protein of unknown function (DUF1510) MIF4G (PF02854, IPR003890, SM00543): MIF4G domain Upf2 (PF04050, IPR007193): Up-frameshift suppressor 2 MIP-T3 (PF10243): Microtubule-binding protein MIP-T3 SUFU_C (PF12470, IPR024314): Suppressor of Fused Gli/Ci N terminal binding domain |
118 |
VIM | suppressor | 15 | 0.451 | 18.554 | Filament (PF00038, IPR001664): Intermediate filament protein Filament_head (PF04732, IPR006821): Intermediate filament head (DNA binding) region |
119 |
VPS29 | interactor | 5 | 0.700 | 2.167 | Metallophos_2 (PF12850, IPR024654): Calcineurin-like phosphoesterase superfamily domain |
120 |
XPNPEP1 | interactor | 4 | 0.833 | 0.500 | Creatinase_N (PF01321, IPR000587): Creatinase/Prolidase N-terminal domain Peptidase_M24 (PF00557, IPR001714): Metallopeptidase family M24 Peptidase_M24_C (PF16188, IPR032416): C-terminal region of peptidase_M24 Creatinase_N_2 (PF16189): Creatinase/Prolidase N-terminal domain |
121 |
YWHAG | protein found in more fusions | 19 | 0.464 | 24.801 | 14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein |
122 |
ZG16 | interactor | 1 | 0 | 0 | Jacalin (PF01419, IPR001229, SM00915): Jacalin-like lectin domain Beta-prism_lec (PF16458, IPR032496): Beta-prism lectin |
123 |
ZYX | suppressor | 11 | 0.436 | 13.381 | DUF1180 (PF06679, IPR009565): Protein of unknown function (DUF1180) LIM (PF00412, IPR001781, SM00132): LIM domain DUF2757 (PF10955, IPR020115): Protein of unknown function (DUF2757) |