1 |
PTPN11 | parental protein | 106 | 0.071 | 7969.784 | SH2 (PF00017, IPR000980, SM00252): SH2 domain Y_phosphatase (PF00102, IPR000242, SM00194): Protein-tyrosine phosphatase |
2 |
BCAR1 | oncoprotein | 11 | 0.673 | 6.313 | Serine_rich (PF08824, IPR014928): Serine rich protein interaction domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain DUF3513 (PF12026, IPR021901): Domain of unknown function (DUF3513) Caskin1-CID (PF16600): Caskin1 CASK-interaction domain |
3 |
BTLA | interactor | 1 | 0 | 0 | V-set (PF07686, IPR013106): Immunoglobulin V-set domain Ig_3 (PF13927): Immunoglobulin domain |
4 |
C6orf25 | interactor | 1 | 0 | 0 | G6B (PF15096, IPR028070): G6B family |
5 |
CAV1 | suppressor | 8 | 0.500 | 6.943 | Caveolin (PF01146, IPR001612): Caveolin |
6 |
CBL | suppressor | 31 | 0.354 | 153.075 | Cbl_N (PF02262, IPR003153): CBL proto-oncogene N-terminal domain 1 Cbl_N2 (PF02761, IPR014741): CBL proto-oncogene N-terminus, EF hand-like domain Cbl_N3 (PF02762, IPR014742): CBL proto-oncogene N-terminus, SH2-like domain UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain Prok-RING_4 (PF14447): Prokaryotic RING finger family 4 zf-RING_4 (PF14570): RING/Ubox like zinc-binding domain |
7 |
CBLB | oncoprotein | 16 | 0.638 | 10.965 | Cbl_N (PF02262, IPR003153): CBL proto-oncogene N-terminal domain 1 Cbl_N2 (PF02761, IPR014741): CBL proto-oncogene N-terminus, EF hand-like domain Cbl_N3 (PF02762, IPR014742): CBL proto-oncogene N-terminus, SH2-like domain UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain Prok-RING_4 (PF14447): Prokaryotic RING finger family 4 PRIMA1 (PF16101): Proline-rich membrane anchor 1 |
8 |
CD274 | oncoprotein | 1 | 0 | 0 | C2-set_2 (PF08205, IPR013162): CD80-like C2-set immunoglobulin domain Herpes_gE (PF02480, IPR003404): Alphaherpesvirus glycoprotein E V-set (PF07686, IPR013106): Immunoglobulin V-set domain |
9 |
CD33 | interactor | 2 | 1.000 | 0 | DUF998 (PF06197, IPR009339): Protein of unknown function (DUF998) ig (PF00047, IPR013151, SM00409): Immunoglobulin domain V-set (PF07686, IPR013106): Immunoglobulin V-set domain |
10 |
CD84 | interactor | 2 | 0 | 0 | I-set (PF07679, IPR013098): Immunoglobulin I-set domain ig (PF00047, IPR013151, SM00409): Immunoglobulin domain Cadherin-like (PF12733, IPR025883): Cadherin-like beta sandwich domain Ig_3 (PF13927): Immunoglobulin domain |
11 |
CDC73 | suppressor | 8 | 0.821 | 2.500 | CDC73_C (PF05179, IPR007852): RNA pol II accessory factor, Cdc73 family, C-terminal CDC73_N (PF16050, IPR032041): Paf1 complex subunit CDC73 N-terminal |
12 |
CDH5 | suppressor | 3 | 1.000 | 0 | Cadherin_C (PF01049, IPR000233): Cadherin cytoplasmic region Cadherin (PF00028, IPR002126, SM00112): Cadherin domain |
13 |
CEACAM1 | suppressor | 2 | 0 | 0 | ig (PF00047, IPR013151, SM00409): Immunoglobulin domain V-set (PF07686, IPR013106): Immunoglobulin V-set domain CYYR1 (PF10873, IPR022640): Cysteine and tyrosine-rich protein 1 Ig_2 (PF13895, IPR007110): Immunoglobulin domain Ig_3 (PF13927): Immunoglobulin domain |
14 |
CHRAC1 | interactor | 2 | 1.000 | 0 | FSAP_sig_propep (PF03032, IPR004275): Frog skin active peptide family signal and propeptide CBFD_NFYB_HMF (PF00808, IPR003958): Histone-like transcription factor (CBF/NF-Y) and archaeal histone |
15 |
CRK | oncoprotein | 20 | 0.479 | 33.753 | SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_2 (PF07653, IPR011511): Variant SH3 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain |
16 |
CRKL | oncoprotein | 22 | 0.433 | 55.397 | SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_2 (PF07653, IPR011511): Variant SH3 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain |
17 |
CSF2RB | interactor | 5 | 0.833 | 0.125 | fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain IL4Ra_N (PF09238, IPR015319): Interleukin-4 receptor alpha chain, N-terminal IL6Ra-bind (PF09240, IPR015321): Interleukin-6 receptor alpha chain, binding Tissue_fac (PF01108, IPR003961): Tissue factor |
18 |
CSF2RBP1 | interactor | 1 | 0 | 0 | NA |
19 |
CSF3R | oncoprotein | 4 | 0.667 | 1.500 | EpoR_lig-bind (PF09067, IPR015152): Erythropoietin receptor, ligand binding fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain Lep_receptor_Ig (PF06328, IPR010457): Ig-like C2-type domain |
20 |
CTNNB1 | oncoprotein | 15 | 0.343 | 50.482 | Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat Atx10homo_assoc (PF09759, IPR019156): Spinocerebellar ataxia type 10 protein domain DUF3361 (PF11841, IPR024574): Domain of unknown function (DUF3361) HEAT_EZ (PF13513): HEAT-like repeat |
21 |
CTR9 | interactor | 8 | 0.786 | 4.000 | DUF702 (PF05142, IPR007818): Domain of unknown function (DUF702) Pap_E4 (PF02711, IPR003861): E4 protein SPT16 (PF08644, IPR013953): FACT complex subunit (SPT16/CDC68) TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat DUF2175 (PF09943, IPR018686): Uncharacterized protein conserved in archaea (DUF2175) TPR_6 (PF13174, IPR019734): Tetratricopeptide repeat TPR_8 (PF13181, IPR019734): Tetratricopeptide repeat TPR_11 (PF13414, IPR011990): TPR repeat TPR_12 (PF13424): Tetratricopeptide repeat TPR_14 (PF13428): Tetratricopeptide repeat TPR_16 (PF13432): Tetratricopeptide repeat TPR_19 (PF14559): Tetratricopeptide repeat |
22 |
CXCR4 | interactor | 5 | 0.700 | 1.300 | 7tm_1 (PF00001, IPR000276): 7 transmembrane receptor (rhodopsin family) COX2_TM (PF02790, IPR011759): Cytochrome C oxidase subunit II, transmembrane domain CXCR4_N (PF12109, IPR022726): CXCR4 Chemokine receptor N terminal |
23 |
CYP1A1 | oncoprotein | 1 | 0 | 0 | p450 (PF00067, IPR001128): Cytochrome P450 |
24 |
EFHD2 | interactor | 2 | 1.000 | 0 | SPARC_Ca_bdg (PF10591, IPR019577): Secreted protein acidic and rich in cysteine Ca binding region EF-hand_7 (PF13499, IPR011992): EF-hand domain pair |
25 |
EGFR | oncoprotein | 35 | 0.339 | 188.599 | Furin-like (PF00757, IPR006211): Furin-like cysteine rich region Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase Recep_L_domain (PF01030, IPR000494): Receptor L domain GAPT (PF11770, IPR021082): GRB2-binding adapter (GAPT) GF_recep_IV (PF14843, IPR032778): Growth factor receptor domain IV |
26 |
ELAVL1 | oncoprotein | 22 | 0.190 | 147.703 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
27 |
EPHA2 | suppressor | 9 | 0.893 | 0.672 | fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain Ephrin_rec_like (PF07699, IPR011641): Putative ephrin-receptor like Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SAM_1 (PF00536, IPR021129, SM00454): SAM domain (Sterile alpha motif) DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369) Laminin_EGF (PF00053, IPR002049, SM00180): Laminin EGF domain Ephrin_lbd (PF01404, IPR001090, SM00615): Ephrin receptor ligand binding domain EphA2_TM (PF14575, IPR027936): Ephrin type-A receptor 2 transmembrane domain |
28 |
EPOR | oncoprotein | 10 | 0.622 | 5.587 | EpoR_lig-bind (PF09067, IPR015152): Erythropoietin receptor, ligand binding fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain |
29 |
ERBB2 | oncoprotein | 23 | 0.519 | 35.652 | Furin-like (PF00757, IPR006211): Furin-like cysteine rich region Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase Recep_L_domain (PF01030, IPR000494): Receptor L domain GF_recep_IV (PF14843, IPR032778): Growth factor receptor domain IV |
30 |
ERBB3 | oncoprotein | 11 | 0.822 | 2.062 | Furin-like (PF00757, IPR006211): Furin-like cysteine rich region Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase Recep_L_domain (PF01030, IPR000494): Receptor L domain GF_recep_IV (PF14843, IPR032778): Growth factor receptor domain IV |
31 |
ERBB4 | suppressor | 9 | 0.893 | 0.702 | Furin-like (PF00757, IPR006211): Furin-like cysteine rich region Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase Recep_L_domain (PF01030, IPR000494): Receptor L domain DUF3951 (PF13131, IPR025028): Protein of unknown function (DUF3951) GF_recep_IV (PF14843, IPR032778): Growth factor receptor domain IV |
32 |
FASN | interactor | 4 | 0.667 | 0.286 | Acyl_transf_1 (PF00698, IPR014043): Acyl transferase domain ADH_zinc_N (PF00107, IPR013149): Zinc-binding dehydrogenase ketoacyl-synt (PF00109, IPR014030): Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C (PF02801, IPR014031): Beta-ketoacyl synthase, C-terminal domain KR (PF08659, IPR013968, SM00130): KR domain L27 (PF02828, IPR014775, SM00569): L27 domain Methyltransf_12 (PF08242, IPR013217): Methyltransferase domain PP-binding (PF00550, IPR009081): Phosphopantetheine attachment site Thioesterase (PF00975, IPR001031): Thioesterase domain YjeF_N (PF03853, IPR004443): YjeF-related protein N-terminus ADH_zinc_N_2 (PF13602): Zinc-binding dehydrogenase PS-DH (PF14765, IPR020807): Polyketide synthase dehydratase KAsynt_C_assoc (PF16197, IPR032821): Ketoacyl-synthetase C-terminal extension |
33 |
FCGR2A | interactor | 5 | 0.500 | 4.333 | DUF3827 (PF12877, IPR024606): Domain of unknown function (DUF3827) Ig_2 (PF13895, IPR007110): Immunoglobulin domain ECSCR (PF15820, IPR026247): Endothelial cell-specific chemotaxis regulator |
34 |
FCGR2B | oncoprotein | 2 | 1.000 | 0 | DUF3827 (PF12877, IPR024606): Domain of unknown function (DUF3827) Ig_2 (PF13895, IPR007110): Immunoglobulin domain ECSCR (PF15820, IPR026247): Endothelial cell-specific chemotaxis regulator |
35 |
FCRL3 | interactor | 1 | 0 | 0 | ig (PF00047, IPR013151, SM00409): Immunoglobulin domain V-set (PF07686, IPR013106): Immunoglobulin V-set domain Ig_2 (PF13895, IPR007110): Immunoglobulin domain Ig_3 (PF13927): Immunoglobulin domain Izumo-Ig (PF16706, IPR032699): Izumo-like Immunoglobulin domain |
36 |
FLT1 | oncoprotein | 2 | 1.000 | 0 | C2-set (PF05790, IPR008424): Immunoglobulin C2-set domain I-set (PF07679, IPR013098): Immunoglobulin I-set domain ig (PF00047, IPR013151, SM00409): Immunoglobulin domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase V-set (PF07686, IPR013106): Immunoglobulin V-set domain Ig_2 (PF13895, IPR007110): Immunoglobulin domain Ig_3 (PF13927): Immunoglobulin domain |
37 |
FRS2 | interactor | 7 | 0.810 | 1.387 | IRS (PF02174, IPR002404, SM00310): PTB domain (IRS-1 type) |
38 |
FSD1 | interactor | 2 | 1.000 | 0 | fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain SPRY (PF00622, IPR003877, SM00449): SPRY domain PLAC9 (PF15205, IPR027941): Placenta-specific protein 9 DUF4945 (PF16303, IPR032544): Domain of unknown function (DUF4945) HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1 |
39 |
FYN | oncoprotein | 20 | 0.298 | 72.014 | Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain |
40 |
GAB1 | oncoprotein | 8 | 0.893 | 0.501 | PH (PF00169, IPR001849, SM00233): PH domain |
41 |
GAB2 | oncoprotein | 11 | 0.644 | 6.765 | PH (PF00169, IPR001849, SM00233): PH domain Pheromone (PF08015, IPR012597): Fungal mating-type pheromone |
42 |
GAB3 | interactor | 3 | 0.667 | 0.167 | PH (PF00169, IPR001849, SM00233): PH domain |
43 |
GHR | oncoprotein | 11 | 0.556 | 4.866 | EpoR_lig-bind (PF09067, IPR015152): Erythropoietin receptor, ligand binding fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain GHBP (PF12772, IPR025871): Growth hormone receptor binding |
44 |
GRB2 | oncoprotein | 42 | 0.259 | 384.034 | SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain DUF5093 (PF17011, IPR031533): Domain of unknown function (DUF5093) |
45 |
GSK3B | suppressor | 6 | 0.600 | 2.556 | Pkinase (PF00069, IPR000719): Protein kinase domain |
46 |
HIST1H2BG | oncoprotein | 1 | 0 | 0 | Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4 |
47 |
IGF1R | oncoprotein | 13 | 0.731 | 4.594 | fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain Furin-like (PF00757, IPR006211): Furin-like cysteine rich region Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase Recep_L_domain (PF01030, IPR000494): Receptor L domain |
48 |
IL4R | oncoprotein | 4 | 0.500 | 1.125 | fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain IL4Ra_N (PF09238, IPR015319): Interleukin-4 receptor alpha chain, N-terminal |
49 |
IL6ST | oncoprotein | 9 | 0.722 | 2.434 | fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain IL6Ra-bind (PF09240, IPR015321): Interleukin-6 receptor alpha chain, binding Lep_receptor_Ig (PF06328, IPR010457): Ig-like C2-type domain Pur_ac_phosph_N (PF16656, IPR015914): Purple acid Phosphatase, N-terminal domain |
50 |
INPP5D | interactor | 11 | 0.473 | 21.486 | Exo_endo_phos (PF03372, IPR005135): Endonuclease/Exonuclease/phosphatase family SH2 (PF00017, IPR000980, SM00252): SH2 domain |
51 |
INSR | interactor | 14 | 0.473 | 21.872 | fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain Furin-like (PF00757, IPR006211): Furin-like cysteine rich region Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase Recep_L_domain (PF01030, IPR000494): Receptor L domain |
52 |
IQCB1 | interactor | 3 | 0.667 | 0.500 | DUF1765 (PF08578, IPR013887): Protein of unknown function (DUF1765) IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif HJURP_C (PF12347, IPR022102): Holliday junction regulator protein family C-terminal repeat Condensin2nSMC (PF12422, IPR024741): Condensin II non structural maintenance of chromosomes subunit |
53 |
IRS1 | interactor | 17 | 0.610 | 15.878 | CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal IRS (PF02174, IPR002404, SM00310): PTB domain (IRS-1 type) PH (PF00169, IPR001849, SM00233): PH domain |
54 |
IRS2 | oncoprotein | 12 | 0.667 | 6.190 | CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal IRS (PF02174, IPR002404, SM00310): PTB domain (IRS-1 type) PH (PF00169, IPR001849, SM00233): PH domain Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein PRIMA1 (PF16101): Proline-rich membrane anchor 1 |
55 |
JAK1 | oncoprotein | 21 | 0.405 | 54.927 | FERM_M (PF00373, IPR019748): FERM central domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain |
56 |
JAK2 | oncoprotein | 26 | 0.337 | 104.075 | FERM_M (PF00373, IPR019748): FERM central domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain |
57 |
KIT | oncoprotein | 12 | 0.652 | 7.690 | ig (PF00047, IPR013151, SM00409): Immunoglobulin domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase Ig_2 (PF13895, IPR007110): Immunoglobulin domain Ig_3 (PF13927): Immunoglobulin domain |
58 |
LAIR1 | interactor | 2 | 0 | 0 | Ig_2 (PF13895, IPR007110): Immunoglobulin domain DUF4448 (PF14610, IPR028000): Protein of unknown function (DUF4448) |
59 |
LEO1 | interactor | 8 | 0.821 | 2.500 | Leo1 (PF04004, IPR007149): Leo1-like protein PPP4R2 (PF09184, IPR015267): PPP4R2 EF-1_beta_acid (PF10587, IPR018940): Eukaryotic elongation factor 1 beta central acidic region |
60 |
LGALS3 | oncoprotein | 6 | 0.500 | 3.667 | Gal-bind_lectin (PF00337, IPR001079, SM00908): Galactoside-binding lectin |
61 |
LGALS9 | interactor | 4 | 0.667 | 1.333 | Gal-bind_lectin (PF00337, IPR001079, SM00908): Galactoside-binding lectin Peptidase_C62 (PF12380, IPR024348): Gill-associated viral 3C-like peptidase |
62 |
LNX1 | interactor | 4 | 0.667 | 0.667 | PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) zf-rbx1 (PF12678, IPR024766): RING-H2 zinc finger domain zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger) |
63 |
LRRK1 | interactor | 6 | 0.700 | 1.019 | Roc (PF08477, IPR013684): Ras of Complex, Roc, domain of DAPkinase Pkinase (PF00069, IPR000719): Protein kinase domain TniB (PF05621, IPR008868): Bacterial TniB protein Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies) LRR_8 (PF13855, IPR001611): Leucine rich repeat COR (PF16095, IPR032171): C-terminal of Roc, COR, domain |
64 |
LY9 | interactor | 1 | 0 | 0 | ig (PF00047, IPR013151, SM00409): Immunoglobulin domain V-set (PF07686, IPR013106): Immunoglobulin V-set domain Ig_3 (PF13927): Immunoglobulin domain |
65 |
MAP2K1 | oncoprotein | 3 | 1.000 | 0 | Pkinase (PF00069, IPR000719): Protein kinase domain DUF3216 (PF11505, IPR023108): Protein of unknown function (DUF3216) |
66 |
MAP3K5 | oncoprotein | 6 | 0.800 | 0.400 | Pkinase (PF00069, IPR000719): Protein kinase domain DUF4071 (PF13281, IPR025136): Domain of unknown function (DUF4071) |
67 |
MAPK14 | oncoprotein | 7 | 0.467 | 5.867 | Pkinase (PF00069, IPR000719): Protein kinase domain |
68 |
MPZL1 | interactor | 6 | 0.533 | 5.200 | Adeno_E3_CR2 (PF02439, IPR003470): Adenovirus E3 region protein CR2 FTR1 (PF03239, IPR004923): Iron permease FTR1 family Trp_oprn_chp (PF09534, IPR019051): Tryptophan-associated transmembrane protein (Trp_oprn_chp) V-set (PF07686, IPR013106): Immunoglobulin V-set domain |
69 |
MTPN | interactor | 3 | 0.667 | 0.500 | Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) |
70 |
NTRK1 | oncoprotein | 34 | 0.265 | 273.482 | I-set (PF07679, IPR013098): Immunoglobulin I-set domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase LRR_8 (PF13855, IPR001611): Leucine rich repeat TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain |
71 |
OVCA2 | suppressor | 1 | 0 | 0 | FSH1 (PF03959, IPR005645): Serine hydrolase (FSH1) |
72 |
OXCT1 | interactor | 6 | 0.400 | 4.500 | CoA_trans (PF01144, IPR004165, SM00882): Coenzyme A transferase |
73 |
PAF1 | oncoprotein | 7 | 0.952 | 0.333 | Paf1 (PF03985, IPR007133): Paf1 MIP-T3 (PF10243): Microtubule-binding protein MIP-T3 |
74 |
PDGFRB | oncoprotein | 11 | 0.667 | 4.818 | I-set (PF07679, IPR013098): Immunoglobulin I-set domain ig (PF00047, IPR013151, SM00409): Immunoglobulin domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase V-set (PF07686, IPR013106): Immunoglobulin V-set domain C1-set (PF07654, IPR003597, SM00407): Immunoglobulin C1-set domain Ig_3 (PF13927): Immunoglobulin domain TonB_N (PF16031): TonB N-terminal region |
75 |
PECAM1 | oncoprotein | 6 | 0.800 | 0.900 | C2-set (PF05790, IPR008424): Immunoglobulin C2-set domain V-set (PF07686, IPR013106): Immunoglobulin V-set domain V-set_CD47 (PF08204, IPR013270): CD47 immunoglobulin-like domain Ig_2 (PF13895, IPR007110): Immunoglobulin domain Ig_3 (PF13927): Immunoglobulin domain MAP17 (PF15807, IPR031627): Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 |
76 |
PIK3R1 | oncoprotein | 35 | 0.358 | 167.883 | RhoGAP (PF00620, IPR000198, SM00324): RhoGAP domain SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_2 (PF07653, IPR011511): Variant SH3 domain PI3K_P85_iSH2 (PF16454, IPR032498): Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain |
77 |
PIK3R2 | oncoprotein | 19 | 0.526 | 29.896 | RhoGAP (PF00620, IPR000198, SM00324): RhoGAP domain SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_9 (PF14604, IPR001452): Variant SH3 domain PI3K_P85_iSH2 (PF16454, IPR032498): Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain |
78 |
PILRA | interactor | 1 | 0 | 0 | SKG6 (PF08693, IPR014805): Transmembrane alpha-helix domain V-set (PF07686, IPR013106): Immunoglobulin V-set domain Ig_3 (PF13927): Immunoglobulin domain G6B (PF15096, IPR028070): G6B family |
79 |
PLCG2 | interactor | 8 | 0.679 | 2.372 | C2 (PF00168, IPR000008, SM00239): C2 domain EF-hand_like (PF09279, IPR015359): Phosphoinositide-specific phospholipase C, efhand-like PH (PF00169, IPR001849, SM00233): PH domain SH2 (PF00017, IPR000980, SM00252): SH2 domain PI-PLC-X (PF00388, IPR000909, SM00148): Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y (PF00387, IPR001711, SM00149): Phosphatidylinositol-specific phospholipase C, Y domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain PH_12 (PF16457, IPR001849): Pleckstrin homology domain |
80 |
PPIF | interactor | 1 | 0 | 0 | Pro_isomerase (PF00160, IPR002130): Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD |
81 |
PRLR | oncoprotein | 5 | 0.833 | 0.286 | EpoR_lig-bind (PF09067, IPR015152): Erythropoietin receptor, ligand binding fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain |
82 |
PTK2 | protein found in more fusions | 21 | 0.463 | 56.639 | FERM_M (PF00373, IPR019748): FERM central domain Focal_AT (PF03623, IPR005189): Focal adhesion targeting region Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase UCMA (PF17085, IPR031386): Unique cartilage matrix associated protein |
83 |
PTK2B | interactor | 12 | 0.636 | 5.784 | FERM_M (PF00373, IPR019748): FERM central domain Focal_AT (PF03623, IPR005189): Focal adhesion targeting region Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase |
84 |
RFWD2 | suppressor | 3 | 1.000 | 0 | Herpes_capsid (PF06112, IPR009299): Gammaherpesvirus capsid protein IncA (PF04156, IPR007285): IncA protein WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger) WD40_like (PF17005, IPR031544): WD40-like domain |
85 |
ROS1 | oncoprotein | 2 | 1.000 | 0 | fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369) |
86 |
RPIA | interactor | 4 | 0.667 | 0.667 | Rib_5-P_isom_A (PF06026, IPR004788): Ribose 5-phosphate isomerase A (phosphoriboisomerase A) Sugar-bind (PF04198, IPR007324): Putative sugar-binding domain |
87 |
RTF1 | interactor | 7 | 0.952 | 0.333 | K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain OAD_gamma (PF04277, IPR005899): Oxaloacetate decarboxylase, gamma chain Plus-3 (PF03126, IPR004343): Plus-3 domain V_ATPase_I (PF01496, IPR002490): V-type ATPase 116kDa subunit family YL1 (PF05764, IPR008895): YL1 nuclear protein AAA_23 (PF13476): AAA domain DUF4407 (PF14362, IPR025519): Domain of unknown function (DUF4407) IMUP (PF15761, IPR026621): Immortalisation up-regulated protein |
88 |
SELE | oncoprotein | 2 | 1.000 | 0 | EGF (PF00008, IPR000742, SM00181): EGF-like domain Sushi (PF00084, IPR000436, SM00032): Sushi repeat (SCR repeat) Lectin_C (PF00059, IPR001304, SM00034): Lectin C-type domain |
89 |
SIGLEC11 | interactor | 1 | 0 | 0 | C2-set_2 (PF08205, IPR013162): CD80-like C2-set immunoglobulin domain I-set (PF07679, IPR013098): Immunoglobulin I-set domain V-set (PF07686, IPR013106): Immunoglobulin V-set domain Ig_2 (PF13895, IPR007110): Immunoglobulin domain Ig_3 (PF13927): Immunoglobulin domain |
90 |
SIT1 | interactor | 2 | 1.000 | 0 | DUF4381 (PF14316, IPR025489): Domain of unknown function (DUF4381) SIT (PF15330): SHP2-interacting transmembrane adaptor protein, SIT |
91 |
SLAMF1 | interactor | 4 | 0.667 | 0.400 | ig (PF00047, IPR013151, SM00409): Immunoglobulin domain SLAM (PF06214, IPR010407): Signaling lymphocytic activation molecule (SLAM) protein |
92 |
SLAMF6 | oncoprotein | 1 | 0 | 0 | OAD_gamma (PF04277, IPR005899): Oxaloacetate decarboxylase, gamma chain V-set (PF07686, IPR013106): Immunoglobulin V-set domain Ig_2 (PF13895, IPR007110): Immunoglobulin domain |
93 |
SOCS1 | suppressor | 18 | 0.484 | 31.230 | SH2 (PF00017, IPR000980, SM00252): SH2 domain SOCS_box (PF07525, IPR001496): SOCS box |
94 |
SOCS3 | suppressor | 17 | 0.368 | 40.473 | SH2 (PF00017, IPR000980, SM00252): SH2 domain SOCS_box (PF07525, IPR001496): SOCS box |
95 |
SOS1 | oncoprotein | 11 | 0.655 | 7.627 | Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4 PH (PF00169, IPR001849, SM00233): PH domain RasGEF (PF00617, IPR001895, SM00147): RasGEF domain RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain RasGEF_N (PF00618, IPR000651, SM00229): RasGEF N-terminal motif |
96 |
STAMBP | interactor | 2 | 1.000 | 0 | USP8_dimer (PF08969, IPR015063): USP8 dimerisation domain JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease DUF3526 (PF12040, IPR021913): Domain of unknown function (DUF3526) |
97 |
STAT3 | suppressor | 21 | 0.400 | 63.610 | SH2 (PF00017, IPR000980, SM00252): SH2 domain STAT_alpha (PF01017, IPR013800): STAT protein, all-alpha domain STAT_bind (PF02864, IPR013801): STAT protein, DNA binding domain STAT_int (PF02865, IPR013799, SM00964): STAT protein, protein interaction domain |
98 |
STAT5A | suppressor | 13 | 0.455 | 12.020 | SH2 (PF00017, IPR000980, SM00252): SH2 domain STAT_alpha (PF01017, IPR013800): STAT protein, all-alpha domain STAT_bind (PF02864, IPR013801): STAT protein, DNA binding domain STAT_int (PF02865, IPR013799, SM00964): STAT protein, protein interaction domain |
99 |
STAT5B | oncoprotein | 12 | 0.473 | 13.343 | SH2 (PF00017, IPR000980, SM00252): SH2 domain STAT_alpha (PF01017, IPR013800): STAT protein, all-alpha domain STAT_bind (PF02864, IPR013801): STAT protein, DNA binding domain STAT_int (PF02865, IPR013799, SM00964): STAT protein, protein interaction domain |
100 |
SYNCRIP | interactor | 5 | 0.800 | 0.786 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 (PF11608, IPR024582): Limkain b1 |
101 |
TCEAL1 | interactor | 3 | 0.667 | 0.500 | BEX (PF04538, IPR021156): Brain expressed X-linked like family |
102 |
TREML1 | interactor | 1 | 0 | 0 | V-set (PF07686, IPR013106): Immunoglobulin V-set domain P12 (PF12669): Virus attachment protein p12 family DUF3999 (PF13163, IPR025060): Protein of unknown function (DUF3999) |
103 |
TRIM32 | suppressor | 2 | 0 | 0 | NHL (PF01436, IPR001258): NHL repeat zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger Zn_Tnp_IS1595 (PF12760, IPR024442): Transposase zinc-ribbon domain zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1 |
104 |
TXNIP | suppressor | 3 | 1.000 | 0 | Arrestin_C (PF02752, IPR011022, SM01017): Arrestin (or S-antigen), C-terminal domain Arrestin_N (PF00339, IPR011021): Arrestin (or S-antigen), N-terminal domain |
105 |
VCAM1 | interactor | 7 | 0.429 | 6.175 | C2-set (PF05790, IPR008424): Immunoglobulin C2-set domain I-set (PF07679, IPR013098): Immunoglobulin I-set domain ig (PF00047, IPR013151, SM00409): Immunoglobulin domain V-set (PF07686, IPR013106): Immunoglobulin V-set domain Ig_3 (PF13927): Immunoglobulin domain |
106 |
WDR61 | interactor | 6 | 1.000 | 0 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain |