Find Fusion Network

Fusion ID:
Protein names:

Level of PPIs:
or Upload text file:
Update repository
Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

Powered by Cytoscape Web for: parental proteins PTGES2 (from a repository: Sun Nov 13 09:09:33 2016)

Cytoscape Web will replace the contents your graph
PPI Properties:

Click on nodes
or edges

Layout Tree
Force Directed
Export graph
PDF file
SVG file
SIF file
XML file
GraphML file

Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)13
The number (and %) of the onco-proteins2 (15.38 %)
The number (and %) of the tumor suppressors2 (15.38 %)
Total number of binary PPIs (saturation %)19 (24.36 %)
The number (and %) of affected PPIs13 (68.42 %)
The number of possible different fusions4
PPI diameter2
PPI radius1
The average degree of PPI2.000
Assortativity coefficient-0.5270
The network average Clustering coefficient0.155
The number (and %) of a zero Clustering coefficients10 (76.92 %)
The number (and %) of a zero Betweenness Centrality12 (92.31 %)


List of the fusions

PPI for parental proteins: PTGES2 All fusions
: BG342124;
Proteins found in more fusions MYC (see 1 fusions); PTGES2 (see 1 fusions); HTT (see 1 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Domains (Pfam, InterPro, SMART): description
1 PTGES2parental protein130.015130.000GST_C_2 (PF13410): Glutathione S-transferase, C-terminal domain
GST_N_3 (PF13417, IPR004045): Glutathione S-transferase, N-terminal domain
2 C15orf48interactor21.0000B12D (PF06522, IPR010530): NADH-ubiquinone reductase complex 1 MLRQ subunit
3 C1orf189interactor100DUF4558 (PF15104, IPR029375): Domain of unknown function (DUF4558)
4 COQ9interactor31.0000COQ9 (PF08511, IPR013718): COQ9
5 DLK1suppressor100EGF (PF00008, IPR000742, SM00181): EGF-like domain
EGF_2 (PF07974, IPR013111): EGF-like domain
cEGF (PF12662, IPR026823): Complement Clr-like EGF-like
6 EID3interactor200Nse4_C (PF08743, IPR014854): Nse4 C-terminal
Nse4-Nse3_bdg (PF15412, IPR029225): Binding domain of Nse4/EID3 to Nse3-MAGE
7 EXOSC10interactor100DNA_pol_A_exo1 (PF01612, IPR002562, SM00474): 3'-5' exonuclease
HRDC (PF00570, IPR002121, SM00341): HRDC domain
PMC2NT (PF08066, IPR012588): PMC2NT (NUC016) domain
Sec62 (PF03839, IPR004728): Translocation protein Sec62
8 H2AFXsuppressor100Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
Histone_H2A_C (PF16211, IPR032454): C-terminus of histone H2A
9 HTTprotein found in more fusions200HEAT (PF02985, IPR000357): HEAT repeat
SPX (PF03105, IPR004331): SPX domain
TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
DUF3652 (PF12372, IPR024613): Huntingtin protein region
Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region
HEAT_EZ (PF13513): HEAT-like repeat
HEAT_2 (PF13646): HEAT repeats
10 MYConcoprotein200HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
Myc-LZ (PF02344, IPR003327): Myc leucine zipper domain
Myc_N (PF01056, IPR012682): Myc amino-terminal region
11 NDUFA4interactor200B12D (PF06522, IPR010530): NADH-ubiquinone reductase complex 1 MLRQ subunit
12 SHISA2interactor100Shisa (PF13908, IPR026910): Wnt and FGF inhibitory regulator
13 UQCR11interactor100UCR_6-4kD (PF08997, IPR015089): Ubiquinol-cytochrome C reductase complex, 6.4kD protein

B a c k    t o    T o p ⇑