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Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

Powered by Cytoscape Web for: parental proteins PSPH (from a repository: Fri Nov 11 23:12:22 2016)
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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)10
The number (and %) of the onco-proteins2 (20.00 %)
The number (and %) of the tumor suppressors0 (0.00 %)
Total number of binary PPIs (saturation %)14 (31.11 %)
The number (and %) of affected PPIs10 (71.43 %)
The number of possible different fusions4
PPI diameter2
PPI radius1
The average degree of PPI1.800
Assortativity coefficient0
The network average Clustering coefficient0.000
The number (and %) of a zero Clustering coefficients10 (100.00 %)
The number (and %) of a zero Betweenness Centrality9 (90.00 %)

ACTIVE INTERACTORS


List of the fusions

Proteins found in more fusions PSPH (see 2 fusions); ATXN1 (see 3 fusions); SHC1 (see 1 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 PSPHparental protein10072.000Hydrolase (PF00702, IPR023214): haloacid dehalogenase-like hydrolase
2 ASF1Binteractor100ASF1_hist_chap (PF04729, IPR006818): ASF1 like histone chaperone
3 ATXN1protein found in more fusions200AXH (PF08517, IPR013723, SM00536): Ataxin-1 and HBP1 module (AXH)
Spt20 (PF12090, IPR021950): Spt20 family
ATXN-1_C (PF12547, IPR020997): Capicua transcriptional repressor modulator
Cnd1_N (PF12922, IPR024324): non-SMC mitotic condensation complex subunit 1, N-term
4 FLAD1interactor200MoCF_biosynth (PF00994, IPR001453, SM00852): Probable molybdopterin binding domain
PAPS_reduct (PF01507, IPR002500): Phosphoadenosine phosphosulfate reductase family
5 OGTinteractor100TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
TPR_11 (PF13414, IPR011990): TPR repeat
TPR_12 (PF13424): Tetratricopeptide repeat
Glyco_transf_41 (PF13844, IPR029489): Glycosyl transferase family 41
TPR_19 (PF14559): Tetratricopeptide repeat
6 PHGDHinteractor1002-Hacid_dh_C (PF02826, IPR006140): D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
7 PRPSAP1interactor200Pribosyltran_N (PF13793, IPR029099): N-terminal domain of ribose phosphate pyrophosphokinase
Pribosyl_synth (PF14572, IPR005946): Phosphoribosyl synthetase-associated domain
8 SHC1oncoprotein200PID (PF00640, IPR006020, SM00462): Phosphotyrosine interaction domain (PTB/PID)
SH2 (PF00017, IPR000980, SM00252): SH2 domain
9 STYXL1interactor100DSPc (PF00782, IPR020422, SM00195): Dual specificity phosphatase, catalytic domain
Rhodanese (PF00581, IPR001763, SM00450): Rhodanese-like domain
10 TIMM8Binteractor100zf-Tim10_DDP (PF02953, IPR004217): Tim10/DDP family zinc finger

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