1 |
PSMC2 | parental protein | 149 | 0.185 | 7643.768 | AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA) |
2 |
ABCE1 | interactor | 18 | 0.522 | 17.242 | ABC_tran (PF00005, IPR003439): ABC transporter Fer4 (PF00037, IPR001450): 4Fe-4S binding domain RLI (PF04068, IPR007209): Possible Fer4-like domain in RNase L inhibitor, RLI SMC_N (PF02463, IPR003395): RecF/RecN/SMC N terminal domain Fer4_7 (PF12838, IPR001450): 4Fe-4S dicluster domain AAA_29 (PF13555): P-loop containing region of AAA domain |
3 |
ACADM | oncoprotein | 12 | 0.500 | 18.942 | Acyl-CoA_dh_1 (PF00441, IPR009075): Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M (PF02770, IPR006091): Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N (PF02771, IPR013786): Acyl-CoA dehydrogenase, N-terminal domain |
4 |
ADRM1 | interactor | 49 | 0.755 | 34.685 | Proteasom_Rpn13 (PF04683, IPR006773): Proteasome complex subunit Rpn13 ubiquitin receptor GET2 (PF08690, IPR028143): GET complex subunit GET2 RPN13_C (PF16550, IPR032368): UCH-binding domain |
5 |
AMBRA1 | interactor | 32 | 0.696 | 28.293 | Acyl_CoA_thio (PF02551, IPR025652): Acyl-CoA thioesterase eIF2A (PF08662, IPR013979): Eukaryotic translation initiation factor eIF2A WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Spt20 (PF12090, IPR021950): Spt20 family ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain |
6 |
AMFR | oncoprotein | 24 | 0.743 | 17.179 | CUE (PF02845, IPR003892, SM00546): CUE domain UbiA (PF01040, IPR000537): UbiA prenyltransferase family zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain |
7 |
ATG4C | interactor | 6 | 0.733 | 1.107 | Peptidase_C54 (PF03416, IPR005078): Peptidase family C54 |
8 |
ATXN7 | interactor | 9 | 0.667 | 5.140 | DUF1180 (PF06679, IPR009565): Protein of unknown function (DUF1180) SCA7 (PF08313, IPR013243): SCA7, zinc-binding domain Macoilin (PF09726, IPR019130): Transmembrane protein DUF3505 (PF12013, IPR022698): Protein of unknown function (DUF3505) IHABP4_N (PF16174, IPR032381): Intracellular hyaluronan-binding protein 4 N-terminal |
9 |
BAG3 | oncoprotein | 29 | 0.619 | 33.815 | BAG (PF02179, IPR003103, SM00264): BAG domain WW (PF00397, IPR001202, SM00456): WW domain |
10 |
CAD | oncoprotein | 28 | 0.415 | 62.605 | Amidohydro_1 (PF01979, IPR006680): Amidohydrolase family CPSase_L_D2 (PF02786, IPR005479): Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 (PF02787, IPR005480, SM01096): Carbamoyl-phosphate synthetase large chain, oligomerisation domain CPSase_sm_chain (PF00988, IPR002474, SM01097): Carbamoyl-phosphate synthase small chain, CPSase domain GATase (PF00117, IPR017926): Glutamine amidotransferase class-I MGS (PF02142, IPR011607, SM00851): MGS-like domain OTCace (PF00185, IPR006131): Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N (PF02729, IPR006132): Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain ATPgrasp_Ter (PF15632, IPR011226): ATP-grasp in the biosynthetic pathway with Ter operon |
11 |
CANX | interactor | 17 | 0.419 | 28.816 | Calreticulin (PF00262, IPR001580): Calreticulin family DUF1510 (PF07423, IPR009988): Protein of unknown function (DUF1510) TRAP_alpha (PF03896, IPR005595): Translocon-associated protein (TRAP), alpha subunit |
12 |
CCDC74B | interactor | 20 | 1.000 | 0 | CCDC92 (PF14916): Coiled-coil domain of unknown function CCDC74_C (PF14917, IPR029422): Coiled coil protein 74, C terminal |
13 |
CCT2 | interactor | 33 | 0.430 | 71.628 | Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family |
14 |
CCT3 | interactor | 33 | 0.453 | 70.528 | Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family |
15 |
CCT4 | interactor | 28 | 0.437 | 48.565 | Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family |
16 |
CCT6A | interactor | 25 | 0.537 | 30.887 | Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family |
17 |
CCT6B | interactor | 11 | 0.655 | 5.640 | Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family |
18 |
CCT8 | interactor | 26 | 0.505 | 34.145 | Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family |
19 |
CDC5L | interactor | 35 | 0.453 | 84.211 | OmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like) Pox_A_type_inc (PF04508, IPR007596): Viral A-type inclusion protein repeat Cir_N (PF10197, IPR019339, SM01083): N-terminal domain of CBF1 interacting co-repressor CIR Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain Myb_Cef (PF11831, IPR021786): pre-mRNA splicing factor component Myb_DNA-bind_6 (PF13921): Myb-like DNA-binding domain |
20 |
CIITA | oncoprotein | 7 | 0.429 | 4.467 | NACHT (PF05729): NACHT domain LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies) LRR_6 (PF13516, IPR001611): Leucine Rich repeat |
21 |
CLIP1 | oncoprotein | 2 | 1.000 | 0 | ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16) CAP_GLY (PF01302, IPR000938, SM01052): CAP-Gly domain CP12 (PF02672, IPR003823, SM01093): CP12 domain DASH_Hsk3 (PF08227, IPR013183): DASH complex subunit Hsk3 like DUF848 (PF05852, IPR008566): Gammaherpesvirus protein of unknown function (DUF848) FlaC_arch (PF05377, IPR008039): Flagella accessory protein C (FlaC) FliJ (PF02050, IPR012823): Flagellar FliJ protein Lectin_N (PF03954, IPR005640): Hepatic lectin, N-terminal domain SlyX (PF04102, IPR007236): SlyX ApoO (PF09769, IPR019166): Apolipoprotein O Ax_dynein_light (PF10211, IPR019347): Axonemal dynein light chain ADIP (PF11559, IPR021622): Afadin- and alpha -actinin-Binding TMF_DNA_bd (PF12329, IPR022092): TATA element modulatory factor 1 DNA binding DUF4200 (PF13863, IPR025252): Domain of unknown function (DUF4200) Leu_zip (PF15294): Leucine zipper CLIP1_ZNF (PF16641, IPR032108): CLIP1 zinc knuckle PKcGMP_CC (PF16808, IPR031831): Coiled-coil N-terminus of cGMP-dependent protein kinase |
22 |
COX7A2 | interactor | 1 | 0 | 0 | COX7a (PF02238, IPR003177): Cytochrome c oxidase subunit VII |
23 |
CRY2 | protein found in more fusions | 19 | 0.464 | 17.004 | DNA_photolyase (PF00875, IPR006050): DNA photolyase FAD_binding_7 (PF03441, IPR005101): FAD binding domain of DNA photolyase |
24 |
CUL3 | protein found in more fusions | 47 | 0.274 | 300.850 | Cullin (PF00888, IPR001373, SM00182): Cullin family Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain WAC_Acf1_DNA_bd (PF10537, IPR013136): ATP-utilising chromatin assembly and remodelling N-terminal |
25 |
DCTN2 | interactor | 20 | 0.556 | 21.136 | Dynamitin (PF04912): Dynamitin |
26 |
DNAJA1 | interactor | 27 | 0.481 | 47.985 | DnaJ (PF00226, IPR001623, SM00271): DnaJ domain DnaJ_C (PF01556, IPR002939): DnaJ C terminal domain |
27 |
DNAJA4 | interactor | 14 | 0.571 | 8.983 | DnaJ (PF00226, IPR001623, SM00271): DnaJ domain DnaJ_C (PF01556, IPR002939): DnaJ C terminal domain |
28 |
FBXO6 | interactor | 28 | 0.389 | 59.269 | FBA (PF04300, IPR007397): F-box associated region F-box-like (PF12937, IPR001810): F-box-like |
29 |
FKBP8 | protein found in more fusions | 33 | 0.891 | 11.886 | FKBP_C (PF00254, IPR001179): FKBP-type peptidyl-prolyl cis-trans isomerase TPR_9 (PF13371, IPR011990): Tetratricopeptide repeat TPR_16 (PF13432): Tetratricopeptide repeat Fis1_TPR_C (PF14853, IPR028061): Fis1 C-terminal tetratricopeptide repeat |
30 |
FTSJ3 | interactor | 8 | 0.536 | 3.463 | DUF1764 (PF08576, IPR013885): Eukaryotic protein of unknown function (DUF1764) FtsJ (PF01728, IPR002877): FtsJ-like methyltransferase M16C_assoc (PF08367, IPR013578): Peptidase M16C associated Orthopox_F8 (PF05886, IPR008726): Orthopoxvirus F8 protein Spb1_C (PF07780, IPR012920): Spb1 C-terminal domain DUF3381 (PF11861, IPR024576): Domain of unknown function (DUF3381) RRP14 (PF15459, IPR029188): 60S ribosome biogenesis protein Rrp14 |
31 |
GFPT1 | interactor | 15 | 0.438 | 21.102 | SIS (PF01380, IPR001347): SIS domain GATase_6 (PF13522): Glutamine amidotransferase domain |
32 |
GRB2 | oncoprotein | 19 | 0.412 | 22.393 | SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain DUF5093 (PF17011, IPR031533): Domain of unknown function (DUF5093) |
33 |
GRK5 | protein found in more fusions | 9 | 0.536 | 3.353 | Pkinase (PF00069, IPR000719): Protein kinase domain RGS (PF00615, IPR000342, SM00315): Regulator of G protein signaling domain |
34 |
GTF2B | interactor | 7 | 0.429 | 5.187 | Cyclin_C (PF02984, IPR004367): Cyclin, C-terminal domain TFIIB (PF00382, IPR013150): Transcription factor TFIIB repeat TF_Zn_Ribbon (PF08271, IPR013137): TFIIB zinc-binding |
35 |
GTF2F1 | interactor | 9 | 0.417 | 10.632 | TFIIF_alpha (PF05793, IPR008851): Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) |
36 |
GTF2H1 | oncoprotein | 5 | 0.700 | 1.733 | BSD (PF03909, IPR005607, SM00751): BSD domain PH_TFIIH (PF08567, IPR013876): TFIIH p62 subunit, N-terminal domain |
37 |
HERC3 | interactor | 12 | 0.530 | 8.844 | RCC1 (PF00415, IPR000408): Regulator of chromosome condensation (RCC1) repeat HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase) RCC1_2 (PF13540): Regulator of chromosome condensation (RCC1) repeat |
38 |
HSPA4 | interactor | 25 | 0.283 | 91.793 | Herpes_ICP4_N (PF03584, IPR005206): Herpesvirus ICP4-like protein N-terminal region HSP70 (PF00012, IPR013126): Hsp70 protein TP53IP5 (PF15331, IPR029290): Cellular tumour antigen p53-inducible 5 |
39 |
HUWE1 | oncoprotein | 57 | 0.470 | 260.336 | BUD22 (PF09073, IPR015158): BUD22 DUF908 (PF06012, IPR010309): Domain of Unknown Function (DUF908) DUF913 (PF06025, IPR010314): Domain of Unknown Function (DUF913) FdhE (PF04216, IPR006452): Protein involved in formate dehydrogenase formation HABP4_PAI-RBP1 (PF04774, IPR006861): Hyaluronan / mRNA binding family Ku_C (PF03730, IPR005160): Ku70/Ku80 C-terminal arm Merozoite_SPAM (PF07133, IPR010784): Merozoite surface protein (SPAM) Mucin (PF01456, IPR000458): Mucin-like glycoprotein Nop14 (PF04147, IPR007276): Nop14-like family PBP_sp32 (PF07222, IPR009865): Proacrosin binding protein sp32 RNA_pol_Rpc4 (PF05132, IPR007811): RNA polymerase III RPC4 TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain WWE (PF02825, IPR004170, SM00678): WWE domain HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase) Tim54 (PF11711, IPR021056): Inner membrane protein import complex subunit Tim54 U1snRNP70_N (PF12220, IPR022023): U1 small nuclear ribonucleoprotein of 70kDa MW N terminal DUF4414 (PF14377, IPR025527): Domain of unknown function (DUF4414) |
40 |
INSIG2 | interactor | 18 | 0.712 | 8.430 | INSIG (PF07281, IPR025929): Insulin-induced protein (INSIG) |
41 |
IPO4 | interactor | 8 | 0.500 | 2.131 | HEAT (PF02985, IPR000357): HEAT repeat IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain RIX1 (PF08167, IPR012583): rRNA processing/ribosome biogenesis UME (PF08064, IPR012993, SM00802): UME (NUC010) domain HEAT_PBS (PF03130, IPR004155, SM00567): PBS lyase HEAT-like repeat Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region HEAT_EZ (PF13513): HEAT-like repeat HEAT_2 (PF13646): HEAT repeats WRNPLPNID (PF15017): Putative WW-binding domain and destruction box |
42 |
KIAA0368 | interactor | 26 | 0.600 | 42.174 | HEAT (PF02985, IPR000357): HEAT repeat IFRD (PF05004, IPR007701): Interferon-related developmental regulator (IFRD) CLASP_N (PF12348, IPR024395): CLASP N terminal MMS19_C (PF12460, IPR024687): RNAPII transcription regulator C-terminal Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region Sec7_N (PF12783, IPR032691): Guanine nucleotide exchange factor in Golgi transport N-terminal Ecm29 (PF13001, IPR024372): Proteasome stabiliser HEAT_EZ (PF13513): HEAT-like repeat HEAT_2 (PF13646): HEAT repeats |
43 |
KPNA6 | interactor | 4 | 0.833 | 0.182 | Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat IBB (PF01749, IPR002652): Importin beta binding domain Arm_3 (PF16186, IPR032413): Atypical Arm repeat |
44 |
LDHA | interactor | 16 | 0.410 | 24.977 | Ldh_1_C (PF02866, IPR022383): lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N (PF00056, IPR001236): lactate/malate dehydrogenase, NAD binding domain |
45 |
LDHB | interactor | 16 | 0.476 | 28.107 | Ldh_1_C (PF02866, IPR022383): lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N (PF00056, IPR001236): lactate/malate dehydrogenase, NAD binding domain |
46 |
MAP3K5 | oncoprotein | 8 | 0.714 | 0.949 | Pkinase (PF00069, IPR000719): Protein kinase domain DUF4071 (PF13281, IPR025136): Domain of unknown function (DUF4071) |
47 |
MAPT | protein found in more fusions | 7 | 0.867 | 0.268 | Tubulin-binding (PF00418, IPR001084): Tau and MAP protein, tubulin-binding repeat |
48 |
MCFD2 | interactor | 10 | 0.867 | 0.932 | EF-hand_7 (PF13499, IPR011992): EF-hand domain pair |
49 |
MID1 | oncoprotein | 17 | 0.792 | 5.728 | Baculo_PEP_C (PF04513, IPR007601): Baculovirus polyhedron envelope protein, PEP, C terminus fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain SPRY (PF00622, IPR003877, SM00449): SPRY domain DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369) zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger PRY (PF13765, IPR006574, SM00589): SPRY-associated domain zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger zf-C3HC4_4 (PF15227): zinc finger of C3HC4-type, RING |
50 |
MID2 | interactor | 10 | 0.722 | 1.970 | fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain SPRY (PF00622, IPR003877, SM00449): SPRY domain zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger PRY (PF13765, IPR006574, SM00589): SPRY-associated domain zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger CEBP_ZZ (PF16366, IPR032296): Cytoplasmic polyadenylation element-binding protein ZZ domain APC_u15 (PF16636): Unstructured region on APC between APC_crr regions 5 and 6 |
51 |
MRPS16 | interactor | 5 | 1.000 | 0 | Ribosomal_S16 (PF00886, IPR000307): Ribosomal protein S16 FtsK_4TM (PF13491, IPR025199): 4TM region of DNA translocase FtsK/SpoIIIE |
52 |
MTCH1 | interactor | 11 | 0.873 | 1.488 | YdjM (PF04307, IPR007404): LexA-binding, inner membrane-associated putative hydrolase Mito_carr (PF00153, IPR018108): Mitochondrial carrier protein |
53 |
MTMR1 | interactor | 1 | 0 | 0 | GRAM (PF02893, IPR004182, SM00568): GRAM domain Myotub-related (PF06602, IPR010569): Myotubularin-like phosphatase domain 3-PAP (PF12578, IPR022587): Myotubularin-associated protein Myb_CC_LHEQLE (PF14379, IPR025756): MYB-CC type transfactor, LHEQLE motif |
54 |
MYC | oncoprotein | 39 | 0.411 | 154.515 | HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain Myc-LZ (PF02344, IPR003327): Myc leucine zipper domain Myc_N (PF01056, IPR012682): Myc amino-terminal region |
55 |
NDC80 | protein found in more fusions | 8 | 0.667 | 2.198 | DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664) Ly49 (PF08391, IPR013600): Ly49-like protein, N-terminal region Ndc80_HEC (PF03801, IPR005550): HEC/Ndc80p family SlyX (PF04102, IPR007236): SlyX ADIP (PF11559, IPR021622): Afadin- and alpha -actinin-Binding TMF_TATA_bd (PF12325, IPR022091): TATA element modulatory factor 1 TATA binding Muted (PF14942, IPR017243): Organelle biogenesis, Muted-like protein |
56 |
NDRG1 | suppressor | 10 | 0.378 | 9.140 | Ndr (PF03096, IPR004142): Ndr family |
57 |
NEURL4 | interactor | 3 | 0.667 | 0.250 | Neuralized (PF07177, IPR006573, SM00588): Neuralized |
58 |
NFS1 | interactor | 3 | 1.000 | 0 | Aminotran_5 (PF00266, IPR000192): Aminotransferase class-V |
59 |
NOS2 | interactor | 36 | 0.652 | 38.556 | FAD_binding_1 (PF00667, IPR003097): FAD binding domain Flavodoxin_1 (PF00258, IPR008254): Flavodoxin NAD_binding_1 (PF00175, IPR001433): Oxidoreductase NAD-binding domain NO_synthase (PF02898, IPR004030): Nitric oxide synthase, oxygenase domain |
60 |
NTRK1 | oncoprotein | 78 | 0.278 | 948.575 | I-set (PF07679, IPR013098): Immunoglobulin I-set domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase LRR_8 (PF13855, IPR001611): Leucine rich repeat TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain |
61 |
NXF1 | interactor | 29 | 0.312 | 117.151 | NTF2 (PF02136, IPR002075): Nuclear transport factor 2 (NTF2) domain Tap-RNA_bind (PF09162, IPR015245): Tap, RNA-binding TAP_C (PF03943, IPR005637, SM00804): TAP C-terminal domain LRR_8 (PF13855, IPR001611): Leucine rich repeat |
62 |
PAAF1 | interactor | 23 | 0.964 | 0.629 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain |
63 |
PARK2 | suppressor | 54 | 0.586 | 154.447 | IBR (PF01485, IPR002867, SM00647): IBR domain, a half RING-finger domain ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family |
64 |
PCDH10 | suppressor | 2 | 1.000 | 0 | Cadherin_2 (PF08266, IPR013164): Cadherin-like K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain Cadherin (PF00028, IPR002126, SM00112): Cadherin domain Cadherin_3 (PF16184): Cadherin-like Cadherin_C_2 (PF16492, IPR032455): Cadherin cytoplasmic C-terminal |
65 |
PCK1 | interactor | 20 | 0.553 | 21.822 | PEPCK (PF00821, IPR008209): Phosphoenolpyruvate carboxykinase |
66 |
PMS2 | oncoprotein | 9 | 0.611 | 5.093 | DNA_mis_repair (PF01119, IPR013507): DNA mismatch repair protein, C-terminal domain MORN_2 (PF07661, IPR011652): MORN repeat variant MutL_C (PF08676, IPR014790, SM00853): MutL C terminal dimerisation domain HATPase_c_3 (PF13589): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase |
67 |
POLR2M | interactor | 3 | 0.667 | 0.667 | GCOM2 (PF15328, IPR026213): Putative GRINL1B complex locus protein 2 |
68 |
POMP | interactor | 23 | 0.784 | 15.191 | UMP1 (PF05348, IPR008012): Proteasome maturation factor UMP1 |
69 |
PSMA1 | interactor | 60 | 0.624 | 136.997 | Proteasome (PF00227, IPR001353): Proteasome subunit Proteasome_A_N (PF10584, IPR000426, SM00948): Proteasome subunit A N-terminal signature |
70 |
PSMA2 | interactor | 65 | 0.596 | 129.237 | Proteasome (PF00227, IPR001353): Proteasome subunit Proteasome_A_N (PF10584, IPR000426, SM00948): Proteasome subunit A N-terminal signature |
71 |
PSMA3 | interactor | 63 | 0.595 | 199.768 | Proteasome (PF00227, IPR001353): Proteasome subunit Proteasome_A_N (PF10584, IPR000426, SM00948): Proteasome subunit A N-terminal signature |
72 |
PSMA4 | interactor | 53 | 0.706 | 62.348 | Proteasome (PF00227, IPR001353): Proteasome subunit U79_P34 (PF03064, IPR004138): HSV U79 / HCMV P34 Proteasome_A_N (PF10584, IPR000426, SM00948): Proteasome subunit A N-terminal signature |
73 |
PSMA5 | oncoprotein | 61 | 0.592 | 149.135 | Proteasome (PF00227, IPR001353): Proteasome subunit Proteasome_A_N (PF10584, IPR000426, SM00948): Proteasome subunit A N-terminal signature |
74 |
PSMA6 | interactor | 63 | 0.592 | 155.914 | Proteasome (PF00227, IPR001353): Proteasome subunit Proteasome_A_N (PF10584, IPR000426, SM00948): Proteasome subunit A N-terminal signature |
75 |
PSMA7 | protein found in more fusions | 57 | 0.682 | 77.803 | Proteasome (PF00227, IPR001353): Proteasome subunit Peptidase_C65 (PF10275, IPR019400): Peptidase C65 Otubain Proteasome_A_N (PF10584, IPR000426, SM00948): Proteasome subunit A N-terminal signature |
76 |
PSMA8 | interactor | 31 | 0.974 | 0.936 | Proteasome (PF00227, IPR001353): Proteasome subunit Proteasome_A_N (PF10584, IPR000426, SM00948): Proteasome subunit A N-terminal signature Myb_DNA-bind_5 (PF13873, IPR028002): Myb/SANT-like DNA-binding domain |
77 |
PSMB1 | interactor | 51 | 0.749 | 37.127 | Proteasome (PF00227, IPR001353): Proteasome subunit |
78 |
PSMB2 | interactor | 49 | 0.747 | 60.323 | Proteasome (PF00227, IPR001353): Proteasome subunit |
79 |
PSMB3 | protein found in more fusions | 50 | 0.765 | 33.021 | Proteasome (PF00227, IPR001353): Proteasome subunit |
80 |
PSMB4 | interactor | 50 | 0.740 | 43.212 | Integrin_b_cyt (PF08725, IPR014836): Integrin beta cytoplasmic domain Proteasome (PF00227, IPR001353): Proteasome subunit |
81 |
PSMB5 | interactor | 53 | 0.679 | 84.032 | Proteasome (PF00227, IPR001353): Proteasome subunit |
82 |
PSMB6 | interactor | 46 | 0.796 | 33.451 | DUF1502 (PF07397, IPR010871): Repeat of unknown function (DUF1502) Proteasome (PF00227, IPR001353): Proteasome subunit |
83 |
PSMB7 | protein found in more fusions | 49 | 0.808 | 21.842 | Proteasome (PF00227, IPR001353): Proteasome subunit Pr_beta_C (PF12465, IPR024689): Proteasome beta subunits C terminal |
84 |
PSMB8 | interactor | 41 | 0.882 | 11.666 | Proteasome (PF00227, IPR001353): Proteasome subunit |
85 |
PSMB9 | interactor | 40 | 0.907 | 5.843 | Proteasome (PF00227, IPR001353): Proteasome subunit |
86 |
PSMC1 | interactor | 75 | 0.452 | 462.906 | AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA) AAA_3 (PF07726, IPR011703): ATPase family associated with various cellular activities (AAA) DivIC (PF04977, IPR007060): Septum formation initiator DUF815 (PF05673, IPR008533): Protein of unknown function (DUF815) Prot_ATP_ID_OB (PF16450, IPR032501): Proteasomal ATPase OB/ID domain |
87 |
PSMC3 | interactor | 75 | 0.454 | 434.896 | AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA) DUF3713 (PF12506, IPR022186): Protein of unknown function (DUF3713) JIP_LZII (PF16471, IPR032486): JNK-interacting protein leucine zipper II |
88 |
PSMC4 | interactor | 74 | 0.467 | 378.286 | AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA) NTPase_1 (PF03266, IPR004948): NTPase CENP-F_leu_zip (PF10473, IPR019513): Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 AAA_16 (PF13191): AAA ATPase domain |
89 |
PSMC5 | protein found in more fusions | 79 | 0.443 | 448.044 | AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA) Laminin_II (PF06009, IPR010307): Laminin Domain II RILP (PF11461, IPR021563): Rab interacting lysosomal protein AAA_16 (PF13191): AAA ATPase domain |
90 |
PSMC6 | interactor | 69 | 0.514 | 247.385 | AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA) AAA_2 (PF07724, IPR013093): AAA domain (Cdc48 subfamily) TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein Prot_ATP_ID_OB (PF16450, IPR032501): Proteasomal ATPase OB/ID domain |
91 |
PSMD1 | interactor | 66 | 0.560 | 168.323 | PA26 (PF04636, IPR006730): PA26 p53-induced protein (sestrin) PC_rep (PF01851, IPR002015): Proteasome/cyclosome repeat HEAT_2 (PF13646): HEAT repeats |
92 |
PSMD10 | interactor | 29 | 0.766 | 22.536 | Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_4 (PF13637): Ankyrin repeats (many copies) |
93 |
PSMD11 | interactor | 62 | 0.567 | 176.864 | DUF247 (PF03140, IPR004158): Plant protein of unknown function PCI (PF01399, IPR000717, SM00088): PCI domain AAA_16 (PF13191): AAA ATPase domain TPR_12 (PF13424): Tetratricopeptide repeat |
94 |
PSMD12 | interactor | 65 | 0.569 | 153.242 | Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain PCI (PF01399, IPR000717, SM00088): PCI domain |
95 |
PSMD13 | interactor | 59 | 0.621 | 105.895 | Mitovir_RNA_pol (PF05919, IPR008686): Mitovirus RNA-dependent RNA polymerase PCI (PF01399, IPR000717, SM00088): PCI domain |
96 |
PSMD14 | interactor | 65 | 0.576 | 184.775 | JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg (PF13012, IPR024969): Maintenance of mitochondrial structure and function |
97 |
PSMD2 | oncoprotein | 78 | 0.434 | 456.507 | PC_rep (PF01851, IPR002015): Proteasome/cyclosome repeat THAP (PF05485, IPR006612, SM00980): THAP domain HEAT_2 (PF13646): HEAT repeats |
98 |
PSMD3 | interactor | 70 | 0.492 | 276.623 | Rpn3_C (PF08375, IPR013586): Proteasome regulatory subunit C-terminal TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat PCI (PF01399, IPR000717, SM00088): PCI domain Fis1_TPR_C (PF14853, IPR028061): Fis1 C-terminal tetratricopeptide repeat TSKS (PF15358, IPR028214): Testis-specific serine kinase substrate |
99 |
PSMD4 | interactor | 65 | 0.536 | 235.793 | UIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif VWA_2 (PF13519, IPR002035): von Willebrand factor type A domain |
100 |
PSMD5 | interactor | 40 | 0.865 | 18.715 | Proteasom_PSMB (PF10508, IPR019538): Proteasome non-ATPase 26S subunit |
101 |
PSMD6 | interactor | 55 | 0.703 | 55.574 | RPN7 (PF10602, IPR019585): 26S proteasome subunit RPN7 PCI (PF01399, IPR000717, SM00088): PCI domain |
102 |
PSMD7 | interactor | 59 | 0.622 | 134.562 | JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg (PF13012, IPR024969): Maintenance of mitochondrial structure and function Auts2 (PF15336): Autism susceptibility gene 2 protein Coilin_N (PF15862, IPR031722): Coilin N-terminus |
103 |
PSMD8 | interactor | 55 | 0.697 | 59.312 | CSN8_PSD8_EIF3K (PF10075): CSN8/PSMD8/EIF3K family |
104 |
PSMD9 | interactor | 21 | 0.943 | 1.024 | Remorin_C (PF03763, IPR005516): Remorin, C-terminal region DUF2046 (PF09755, IPR019152): Uncharacterized conserved protein H4 (DUF2046) PDZ_2 (PF13180, IPR001478): PDZ domain |
105 |
PSME1 | interactor | 30 | 0.840 | 9.223 | PA28_alpha (PF02251, IPR003185): Proteasome activator pa28 alpha subunit PA28_beta (PF02252, IPR003186): Proteasome activator pa28 beta subunit RNase_H2-Ydr279 (PF09468, IPR019024): Ydr279p protein family (RNase H2 complex component) |
106 |
PSME2 | interactor | 29 | 0.892 | 3.190 | PA28_alpha (PF02251, IPR003185): Proteasome activator pa28 alpha subunit PA28_beta (PF02252, IPR003186): Proteasome activator pa28 beta subunit |
107 |
PSME3 | protein found in more fusions | 30 | 0.783 | 20.395 | PA28_alpha (PF02251, IPR003185): Proteasome activator pa28 alpha subunit PA28_beta (PF02252, IPR003186): Proteasome activator pa28 beta subunit |
108 |
RAB5C | oncoprotein | 6 | 0.600 | 2.111 | Ras (PF00071, IPR001806, SM00173): Ras family |
109 |
RAD21 | oncoprotein | 17 | 0.493 | 19.458 | Rad21_Rec8 (PF04824, IPR006909): Conserved region of Rad21 / Rec8 like protein Rad21_Rec8_N (PF04825, IPR006910): N terminus of Rad21 / Rec8 like protein FAM176 (PF14851): FAM176 family WRNPLPNID (PF15017): Putative WW-binding domain and destruction box |
110 |
RAD23A | oncoprotein | 47 | 0.711 | 107.095 | UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain XPC-binding (PF09280, IPR015360): XPC-binding domain ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family |
111 |
RAD23B | suppressor | 27 | 0.687 | 27.338 | K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain XPC-binding (PF09280, IPR015360): XPC-binding domain ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family DUF3123 (PF11321, IPR021470): Protein of unknown function (DUF3123) |
112 |
RELA | oncoprotein | 15 | 0.407 | 27.262 | DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region RHD_DNA_bind (PF00554, IPR011539): Rel homology DNA-binding domain RHD_dimer (PF16179, IPR032397): Rel homology dimerisation domain |
113 |
RNF185 | interactor | 15 | 0.692 | 4.682 | zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger) |
114 |
RNF2 | interactor | 26 | 0.277 | 76.092 | zf-C4_Topoisom (PF01396, IPR013498): Topoisomerase DNA binding C4 zinc finger zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger) RAWUL (PF16207, IPR032443): RAWUL domain RING finger- and WD40-associated ubiquitin-like |
115 |
RPN1 | oncoprotein | 22 | 0.390 | 56.340 | Ribophorin_I (PF04597, IPR007676): Ribophorin I CtIP_N (PF10482, IPR019518): Tumour-suppressor protein CtIP N-terminal domain |
116 |
RPS21 | interactor | 14 | 0.769 | 4.236 | Ribosomal_S21e (PF01249, IPR001931): Ribosomal protein S21e |
117 |
RPS6KB2 | interactor | 16 | 0.425 | 13.679 | Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain |
118 |
SEC23A | interactor | 12 | 0.409 | 13.105 | Gelsolin (PF00626, IPR007123): Gelsolin repeat Sec23_BS (PF08033, IPR012990): Sec23/Sec24 beta-sandwich domain Sec23_helical (PF04815, IPR006900): Sec23/Sec24 helical domain Sec23_trunk (PF04811, IPR006896): Sec23/Sec24 trunk domain zf-Sec23_Sec24 (PF04810, IPR006895): Sec23/Sec24 zinc finger APP_E2 (PF12925, IPR024329): E2 domain of amyloid precursor protein |
119 |
SHFM1 | interactor | 42 | 0.656 | 58.781 | CLLAC (PF15675, IPR031379): CLLAC-motif containing domain |
120 |
SHMT2 | interactor | 10 | 0.489 | 8.563 | SHMT (PF00464, IPR001085): Serine hydroxymethyltransferase |
121 |
SIRT7 | interactor | 26 | 0.320 | 67.192 | DUF563 (PF04577, IPR007657): Protein of unknown function (DUF563) SIR2 (PF02146, IPR003000): Sir2 family |
122 |
SKIL | suppressor | 3 | 1.000 | 0 | c-SKI_SMAD_bind (PF08782, IPR014890, SM01046): c-SKI Smad4 binding domain DUF489 (PF04356, IPR007451): Protein of unknown function (DUF489) DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972) Neur_chan_memb (PF02932, IPR006029): Neurotransmitter-gated ion-channel transmembrane region Ski_Sno (PF02437, IPR003380): SKI/SNO/DAC family DUF2115 (PF09888, IPR019215): Uncharacterized protein conserved in archaea (DUF2115) |
123 |
SMC1A | oncoprotein | 13 | 0.545 | 11.920 | SMC_N (PF02463, IPR003395): RecF/RecN/SMC N terminal domain |
124 |
SMC3 | oncoprotein | 11 | 0.600 | 9.156 | SMC_N (PF02463, IPR003395): RecF/RecN/SMC N terminal domain |
125 |
SNRNP200 | protein found in more fusions | 16 | 0.467 | 10.377 | DEAD (PF00270, IPR011545): DEAD/DEAH box helicase DUF603 (PF04645, IPR006739): Protein of unknown function, DUF603 Sec63 (PF02889, IPR004179, SM00973): Sec63 Brl domain Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain |
126 |
SNW1 | protein found in more fusions | 36 | 0.417 | 115.002 | SKIP_SNW (PF02731, IPR004015): SKIP/SNW domain PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term SIR4_SID (PF16991, IPR031556): Sir4 SID domain |
127 |
SPRTN | interactor | 9 | 0.500 | 4.689 | GreA_GreB (PF01272, IPR001437): Transcription elongation factor, GreA/GreB, C-term SprT-like (PF10263, IPR006640, SM00731): SprT-like family PRP21_like_P (PF12230, IPR022030): Pre-mRNA splicing factor PRP21 like protein |
128 |
SQSTM1 | oncoprotein | 22 | 0.400 | 39.749 | PB1 (PF00564, IPR000270, SM00666): PB1 domain ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type UBA_5 (PF16577, IPR015940): UBA domain |
129 |
SUCLA2 | interactor | 5 | 0.700 | 2.333 | ATP-grasp_2 (PF08442, IPR013650): ATP-grasp domain Ligase_CoA (PF00549, IPR005811): CoA-ligase nsp7 (PF08716, IPR014828): nsp7 replicase |
130 |
TBP | interactor | 9 | 0.464 | 7.886 | TBP (PF00352, IPR000814): Transcription factor TFIID (or TATA-binding protein, TBP) EPL1 (PF10513, IPR019542): Enhancer of polycomb-like Med3 (PF11593, IPR020998): Mediator complex subunit 3 fungal |
131 |
TPM4 | oncoprotein | 8 | 0.857 | 0.539 | Tropomyosin (PF00261, IPR000533): Tropomyosin Tropomyosin_1 (PF12718, IPR000533): Tropomyosin like |
132 |
TRAF6 | protein found in more fusions | 19 | 0.523 | 23.667 | SlyX (PF04102, IPR007236): SlyX zf-TRAF (PF02176, IPR001293): TRAF-type zinc finger zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger) |
133 |
TRIM5 | interactor | 8 | 0.667 | 1.292 | Baculo_IE-1 (PF05290, IPR007954): Baculovirus immediate-early protein (IE-0) Baculo_PEP_C (PF04513, IPR007601): Baculovirus polyhedron envelope protein, PEP, C terminus SPRY (PF00622, IPR003877, SM00449): SPRY domain zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger TMF_TATA_bd (PF12325, IPR022091): TATA element modulatory factor 1 TATA binding zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger |
134 |
TUBB | interactor | 24 | 0.370 | 70.495 | Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain |
135 |
TXNL1 | interactor | 26 | 0.772 | 11.818 | PITH (PF06201, IPR010400): PITH domain Thioredoxin (PF00085, IPR013766): Thioredoxin |
136 |
UBC | protein found in more fusions | 71 | 0.358 | 589.176 | ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family |
137 |
UBE2C | oncoprotein | 10 | 0.722 | 2.446 | UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme |
138 |
UBQLN1 | protein found in more fusions | 24 | 0.534 | 39.776 | Clathrin-link (PF09268, IPR015348): Clathrin, heavy-chain linker UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain XPC-binding (PF09280, IPR015360): XPC-binding domain ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family Fur_reg_FbpB (PF13040, IPR025004): Fur-regulated basic protein B FAM199X (PF15814, IPR029672): Protein family FAM199X |
139 |
UBQLN2 | protein found in more fusions | 18 | 0.485 | 32.712 | Clathrin-link (PF09268, IPR015348): Clathrin, heavy-chain linker Collagen (PF01391, IPR008160): Collagen triple helix repeat (20 copies) TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain XPC-binding (PF09280, IPR015360): XPC-binding domain ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family SUZ (PF12752, IPR024771): SUZ domain Fur_reg_FbpB (PF13040, IPR025004): Fur-regulated basic protein B |
140 |
UBR2 | interactor | 4 | 0.500 | 1.750 | ClpS (PF02617, IPR003769): ATP-dependent Clp protease adaptor protein ClpS zinc-ribbons_6 (PF07191, IPR010807): zinc-ribbons zf-UBR (PF02207, IPR003126): Putative zinc finger in N-recognin (UBR box) zf-ANAPC11 (PF12861, IPR024991): Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 (PF14634, IPR001841): zinc-RING finger domain |
141 |
UBR5 | protein found in more fusions | 13 | 0.394 | 11.472 | CENP-B_dimeris (PF09026, IPR015115): Centromere protein B dimerisation domain SDA1 (PF05285, IPR007949): SDA1 HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase) PABP (PF00658, IPR002004, SM00517): Poly-adenylate binding protein, unique domain E3_UbLigase_EDD (PF11547, IPR024725): E3 ubiquitin ligase EDD PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term DUF3915 (PF13054, IPR025026): Protein of unknown function (DUF3915) RCDG1 (PF15725, IPR031457): Renal cancer differentiation gene 1 protein |
142 |
UCHL5 | oncoprotein | 51 | 0.739 | 35.832 | Peptidase_C12 (PF01088, IPR001578): Ubiquitin carboxyl-terminal hydrolase, family 1 |
143 |
UFC1 | interactor | 2 | 1.000 | 0 | UFC1 (PF08694, IPR014806): Ubiquitin-fold modifier-conjugating enzyme 1 |
144 |
USP14 | interactor | 31 | 0.789 | 26.054 | UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family |
145 |
VBP1 | interactor | 2 | 1.000 | 0 | Prefoldin (PF02996, IPR004127): Prefoldin subunit |
146 |
VPS26A | protein found in more fusions | 5 | 0.833 | 0.200 | Vps26 (PF03643, IPR005377): Vacuolar protein sorting-associated protein 26 |
147 |
XPO1 | interactor | 28 | 0.220 | 147.787 | CRM1_C (PF08767, IPR014877, SM01102): CRM1 C terminal Hydrolase_3 (PF08282, IPR023214): haloacid dehalogenase-like hydrolase IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain Xpo1 (PF08389, IPR013598): Exportin 1-like protein Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region |
148 |
YBX1 | oncoprotein | 20 | 0.374 | 33.188 | CSD (PF00313, IPR002059): 'Cold-shock' DNA-binding domain PBP1_TM (PF14812, IPR032730): Transmembrane domain of transglycosylase PBP1 at N-terminal FXR_C1 (PF16096, IPR032172): Fragile X-related 1 protein C-terminal region 2 |
149 |
ZCCHC8 | interactor | 11 | 0.582 | 4.838 | Herpes_BLRF2 (PF05812, IPR008642): Herpesvirus BLRF2 protein PSP (PF04046, IPR006568, SM00581): PSP zf-CCHC (PF00098, IPR001878): Zinc knuckle DUF4140 (PF13600, IPR025554): N-terminal domain of unknown function (DUF4140) |