Find Fusion Network

Visualization interactions

Powered by Cytoscape Web for: parental proteins PRKDC (from a repository: Sat Dec 3 06:11:46 2016)

Examples AFF1 MLL ACTN4 + MLLAFF1 + MLLALK + MSNALK + TFGALK + TPM3ALK + TPM4ASXL2 + KAT6AATF1 + FUSBCR + ABL1BCR + FGFR1CCND1 + TACSTD2CD74 + ROS1CDK6 + MLLCOL1A1 + PDGFBCREB3L2 + PPARGCREB3L2 + FUSCREBBP + KAT6ADAZAP1 + MEF2DELL + MLLEPS15 + MLLERG + EWSR1ERG + FUSERG + TMPRSS2ETV5 + TMPRSS2ETV6 + ABL1ETV6 + NTRK3ETV6 + PAX5EWSR1 + FLI1EWSR1 + WT1FOXO1 + PAX3FOXP1 + PAX5FRYL + MLLGAS7 + MLLGMPS + MLLGOLGA5 + RETHOOK3 + RETHOXC13 + NUP98HOXD13 + NUP98MECOM + RUNX1MKL1 + RBM15MLL + MLLT1MLL + MLLT4MLL + MLLT10MLL + PICALMMLLT10 + PICALMNCOA1 + PAX3NIN + PDGFRBNPM1 + RARANRG1 + ODZ4NTRK1 + TFGNUMA1 + RARANUP98 + PHF23PAX5 + ZNF521PBX1 + TCF3RET + TRIM27ROS1 + SLC34A2PML + RARAPRKAR1A + RARAPRKAR1A + RETRUNX1 + RUNX1T1RUNX1 + SH3D19	Cytoscape Web will replace the contents your graph	PPI Properties: Click on nodes or edges
Layout Tree Circle Radial Force Directed Preset
Export graph PNG file PDF file SVG file SIF file XML file GraphML file

Statistics and Network structure information

Statistic of PPI Value(s) The number of interactors (fusion and proteins) 234 The number (and %) of the onco-proteins 81 (34.62 %) The number (and %) of the tumor suppressors 36 (15.38 %) Total number of binary PPIs (saturation %) 2618 (9.60 %) The number (and %) of affected PPIs 234 (8.94 %) The number of possible different fusions 53 PPI diameter 2 PPI radius 1 The average degree of PPI 21.359 Assortativity coefficient -0.2179 The network average Clustering coefficient 0.452 The number (and %) of a zero Clustering coefficients 5 (2.14 %) The number (and %) of a zero Betweenness Centrality 18 (7.69 %)

ACTIVE INTERACTORS

List of the fusions
PPI for parental proteins: PRKDC	All fusions : W28344;
Proteins found in more fusions	GRK5 (see 4 fusions); CTPS2 (see 1 fusions); U2AF2 (see 2 fusions); DCAF1 (see 1 fusions); HSF1 (see 3 fusions); PINK1 (see 3 fusions); PRKDC (see 3 fusions); PRDX1 (see 1 fusions); HDAC5 (see 1 fusions); IKBKB (see 2 fusions); EP300 (see 1 fusions); PCNA (see 1 fusions); DDX5 (see 1 fusions); RPA1 (see 1 fusions); SNW1 (see 1 fusions); POU2F1 (see 1 fusions); HSP90AA1 (see 2 fusions); HSP90AB1 (see 1 fusions); RBBP8 (see 1 fusions); USF1 (see 3 fusions); YY1 (see 2 fusions); PRPF8 (see 3 fusions); BAG3 (see 4 fusions); KAT8 (see 1 fusions); CSNK2A1 (see 1 fusions); SHC1 (see 1 fusions); STAU1 (see 2 fusions); GSK3B (see 1 fusions); CUL7 (see 2 fusions); CSNK2A1/ELAVL1 (see 1 fusions); CUL3 (see 1 fusions); MAPK9 (see 3 fusions); MYC (see 1 fusions); SKI (see 1 fusions); COPS5 (see 1 fusions); PARP1 (see 1 fusions); LRRK2 (see 1 fusions); THRA (see 3 fusions); TP53 (see 3 fusions); AP2M1 (see 3 fusions); ILK (see 1 fusions); LMNA (see 3 fusions); CRY2 (see 3 fusions); LYN (see 2 fusions); NR3C1 (see 8 fusions); NCOA6 (see 1 fusions); SP1 (see 1 fusions); EGFR (see 2 fusions); MCM2 (see 1 fusions); KAT5 (see 3 fusions); HNRNPC (see 1 fusions); NTRK1/TPR (see 1 fusions);

List of active interactors

#	Name	Type	Number of PPI (degree)	Clustering Coefficient	Betweenness Centrality	Domains (Pfam, InterPro, SMART): description
1	PRKDC	parental protein	234	0.084	28337.733	FAT (PF02259, IPR003151): FAT domain FATC (PF02260, IPR003152): FATC domain NUC194 (PF08163, IPR012582): NUC194 domain PI3_PI4_kinase (PF00454, IPR000403, SM00146): Phosphatidylinositol 3- and 4-kinase
2	ABL1	oncoprotein	21	0.400	38.135	Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain F_actin_bind (PF08919, IPR015015, SM00808): F-actin binding SH3_1 (PF00018, IPR001452, SM00326): SH3 domain FRG2 (PF15315, IPR026245): Facioscapulohumeral muscular dystrophy candidate 2
3	ADRB2	interactor	4	0.667	0.154	7tm_1 (PF00001, IPR000276): 7 transmembrane receptor (rhodopsin family)
4	AICDA	interactor	6	0.600	0.560	APOBEC_N (PF08210, IPR013158): APOBEC-like N-terminal domain
5	AIRE	interactor	14	0.359	8.649	PHD (PF00628, IPR019787, SM00249): PHD-finger SAND (PF01342, IPR000770, SM00258): SAND domain HSR (PF03172, IPR004865): HSR domain; Sp100 domain zf-PHD-like (PF15446): PHD/FYVE-zinc-finger like domain
6	AKT1	oncoprotein	30	0.271	149.912	PH (PF00169, IPR001849, SM00233): PH domain Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
7	AKT2	oncoprotein	10	0.400	13.323	PH (PF00169, IPR001849, SM00233): PH domain Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
8	ALOX15	suppressor	1	0	0	Lipoxygenase (PF00305, IPR013819): Lipoxygenase PLAT (PF01477, IPR001024, SM00308): PLAT/LH2 domain
9	ANAPC2	interactor	8	0.536	4.042	ANAPC2 (PF08672, IPR014786, SM01013): Anaphase promoting complex (APC) subunit 2 Cullin (PF00888, IPR001373, SM00182): Cullin family
10	AP1B1	interactor	15	0.476	12.922	Adaptin_N (PF01602, IPR002553): Adaptin N terminal region Alpha_adaptinC2 (PF02883, IPR008152, SM00809): Adaptin C-terminal domain B2-adapt-app_C (PF09066, IPR015151, SM01020): Beta2-adaptin appendage, C-terminal sub-domain
11	AP2M1	protein found in more fusions	17	0.325	34.802	Adap_comp_sub (PF00928, IPR008968): Adaptor complexes medium subunit family Clat_adaptor_s (PF01217, IPR022775): Clathrin adaptor complex small chain
12	AR	oncoprotein	27	0.345	66.842	Androgen_recep (PF02166, IPR001103): Androgen receptor zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
13	ARHGEF6	oncoprotein	2	0	0	CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain Cnn_1N (PF07989, IPR012943): Centrosomin N-terminal motif 1 PH (PF00169, IPR001849, SM00233): PH domain RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain SH3_9 (PF14604, IPR001452): Variant SH3 domain betaPIX_CC (PF16523, IPR032409): betaPIX coiled coil RhoGEF67_u2 (PF16614): Unstructured region two on RhoGEF 6 and 7 RhoGEF67_u1 (PF16615): Unstructured region one on RhoGEF 6 and 7
14	ASB5	interactor	2	1.000	0	Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_5 (PF13857): Ankyrin repeats (many copies) SOCS_box (PF07525, IPR001496): SOCS box
15	ATG101	interactor	3	0.667	0.286	ATG101 (PF07855, IPR012445): Autophagy-related protein 101
16	ATG4C	interactor	1	0	0	Peptidase_C54 (PF03416, IPR005078): Peptidase family C54
17	ATM	suppressor	41	0.241	330.881	FAT (PF02259, IPR003151): FAT domain FATC (PF02260, IPR003152): FATC domain HEAT (PF02985, IPR000357): HEAT repeat PI3_PI4_kinase (PF00454, IPR000403, SM00146): Phosphatidylinositol 3- and 4-kinase TAN (PF11640, IPR021668): Telomere-length maintenance and DNA damage repair ANAPC5 (PF12862, IPR026000): Anaphase-promoting complex subunit 5
18	ATRIP	interactor	8	0.821	0.619	Tropomyosin_1 (PF12718, IPR000533): Tropomyosin like
19	ATRX	oncoprotein	14	0.495	15.567	DDHD (PF02862, IPR004177, SM01127): DDHD domain DTHCT (PF08070, IPR012542): DTHCT (NUC029) region Pap_E4 (PF02711, IPR003861): E4 protein PHD (PF00628, IPR019787, SM00249): PHD-finger Secretin_N_2 (PF07655, IPR011514): Secretin N-terminal domain SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain Zip (PF02535, IPR003689): ZIP Zinc transporter DUF2052 (PF09747, IPR018613): Coiled-coil domain containing protein (DUF2052) Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain DUF2992 (PF11208, IPR016787): Protein of unknown function (DUF2992) DUF3408 (PF11888, IPR021823): Protein of unknown function (DUF3408) PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term SEEEED (PF14797, IPR029394): Serine-rich region of AP3B1, clathrin-adaptor complex FAM176 (PF14851): FAM176 family DUF4746 (PF15928, IPR031827): Domain of unknown function (DUF4746)
20	AUP1	interactor	7	0.381	4.474	CUE (PF02845, IPR003892, SM00546): CUE domain
21	BAG3	oncoprotein	19	0.222	78.783	BAG (PF02179, IPR003103, SM00264): BAG domain WW (PF00397, IPR001202, SM00456): WW domain
22	BECN1	suppressor	7	0.533	2.938	APG6 (PF04111, IPR007243): Autophagy protein Apg6 Ima1_N (PF09779, IPR018617): Ima1 N-terminal domain BH3 (PF15285, IPR029318): Beclin-1 BH3 domain, Bcl-2-interacting
23	BIRC5	interactor	10	0.556	4.514	BIR (PF00653, IPR001370, SM00238): Inhibitor of Apoptosis domain
24	BMI1	oncoprotein	29	0.333	66.753	zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger) RAWUL (PF16207, IPR032443): RAWUL domain RING finger- and WD40-associated ubiquitin-like
25	BRCA1	suppressor	58	0.249	528.114	BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger) BRCT_assoc (PF12820, IPR025994): Serine-rich domain associated with BRCT
26	C14orf166	interactor	23	0.494	36.727	RLL (PF10036, IPR019265): Putative carnitine deficiency-associated protein
27	C1D	interactor	3	0.667	0.250	Sas10_Utp3 (PF04000, IPR007146): Sas10/Utp3/C1D family
28	CAMKK2	oncoprotein	3	0.667	0.143	Pkinase (PF00069, IPR000719): Protein kinase domain
29	CASP3	interactor	14	0.308	32.155	Peptidase_C14 (PF00656, IPR011600): Caspase domain
30	CCDC8	interactor	39	0.317	107.851	Borrelia_P83 (PF05262, IPR007926): Borrelia P83/100 protein SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal PNMA (PF14893, IPR026523): PNMA
31	CCNB1	oncoprotein	14	0.451	15.852	Adeno_E1A (PF02703, IPR003853): Early E1A protein Cyclin_C (PF02984, IPR004367): Cyclin, C-terminal domain Cyclin_N (PF00134, IPR006671): Cyclin, N-terminal domain
32	CDC5L	interactor	65	0.282	503.388	OmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like) Pox_A_type_inc (PF04508, IPR007596): Viral A-type inclusion protein repeat Cir_N (PF10197, IPR019339, SM01083): N-terminal domain of CBF1 interacting co-repressor CIR Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain Myb_Cef (PF11831, IPR021786): pre-mRNA splicing factor component Myb_DNA-bind_6 (PF13921): Myb-like DNA-binding domain
33	CDK2	suppressor	50	0.304	286.803	Kdo (PF06293, IPR010440): Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase (PF00069, IPR000719): Protein kinase domain
34	CENPA	interactor	16	0.419	15.888	Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
35	CFTR	suppressor	9	0.357	6.513	ABC_membrane (PF00664, IPR001140): ABC transporter transmembrane region ABC_tran (PF00005, IPR003439): ABC transporter Roc (PF08477, IPR013684): Ras of Complex, Roc, domain of DAPkinase SMC_N (PF02463, IPR003395): RecF/RecN/SMC N terminal domain Rotamase_2 (PF13145, IPR000297): PPIC-type PPIASE domain CFTR_R (PF14396, IPR025837): Cystic fibrosis TM conductance regulator (CFTR), regulator domain
36	CHAF1A	interactor	16	0.438	21.459	CAF-1_p150 (PF11600): Chromatin assembly factor 1 complex p150 subunit, N-terminal CAF1A (PF12253, IPR022043): Chromatin assembly factor 1 subunit A CAF1-p150_C2 (PF15539, IPR029105): CAF1 complex subunit p150, region binding to CAF1-p60 at C-term CAF1-p150_N (PF15557, IPR029091): CAF1 complex subunit p150, region binding to PCNA
37	CHD1L	interactor	13	0.615	8.164	ATP-synt_E (PF05680, IPR008386): ATP synthase E chain SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
38	CHEK1	suppressor	14	0.615	4.577	Pkinase (PF00069, IPR000719): Protein kinase domain
39	CHEK2	suppressor	8	0.810	0.672	FHA (PF00498, IPR000253, SM00240): FHA domain Pkinase (PF00069, IPR000719): Protein kinase domain
40	CHUK	suppressor	19	0.523	19.486	Pkinase (PF00069, IPR000719): Protein kinase domain IKKbetaNEMObind (PF12179, IPR022007): I-kappa-kinase-beta NEMO binding domain
41	CIB1	interactor	1	0	0	EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
42	CLK1	interactor	8	0.476	6.237	PDGF_N (PF04692, IPR006782): Platelet-derived growth factor, N terminal region Pkinase (PF00069, IPR000719): Protein kinase domain
43	CLN3	interactor	6	0.333	3.552	CLN3 (PF02487, IPR003492): CLN3 protein
44	COPS5	protein found in more fusions	49	0.298	277.374	JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease
45	CRY1	interactor	11	0.311	6.326	DNA_photolyase (PF00875, IPR006050): DNA photolyase FAD_binding_7 (PF03441, IPR005101): FAD binding domain of DNA photolyase
46	CRY2	protein found in more fusions	14	0.359	13.740	DNA_photolyase (PF00875, IPR006050): DNA photolyase FAD_binding_7 (PF03441, IPR005101): FAD binding domain of DNA photolyase
47	CSNK2A1	oncoprotein	39	0.304	192.838	Pkinase (PF00069, IPR000719): Protein kinase domain
48	CTDP1	interactor	4	0.500	1.582	Biotin_lipoyl (PF00364, IPR000089): Biotin-requiring enzyme FCP1_C (PF09309, IPR015388): FCP1, C-terminal NIF (PF03031, IPR004274): NLI interacting factor-like phosphatase SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal Apt1 (PF10351, IPR019443): Golgi-body localisation protein domain TFIIE-A_C (PF11521, IPR021600): C-terminal general transcription factor TFIIE alpha CAF1A (PF12253, IPR022043): Chromatin assembly factor 1 subunit A PTCB-BRCT (PF12738, IPR001357): twin BRCT domain HlyD_D23 (PF16576, IPR032317): Barrel-sandwich domain of CusB or HlyD membrane-fusion
49	CTPS2	protein found in more fusions	8	0.524	7.352	CTP_synth_N (PF06418, IPR017456): CTP synthase N-terminus GATase (PF00117, IPR017926): Glutamine amidotransferase class-I
50	CUL3	protein found in more fusions	58	0.262	410.216	Cullin (PF00888, IPR001373, SM00182): Cullin family Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain WAC_Acf1_DNA_bd (PF10537, IPR013136): ATP-utilising chromatin assembly and remodelling N-terminal
51	CUL5	suppressor	33	0.347	114.837	Cullin (PF00888, IPR001373, SM00182): Cullin family GlutR_dimer (PF00745, IPR015896): Glutamyl-tRNAGlu reductase, dimerisation domain Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
52	CUL7	protein found in more fusions	48	0.354	154.222	ANAPC10 (PF03256, IPR004939): Anaphase-promoting complex, subunit 10 (APC10) Cullin (PF00888, IPR001373, SM00182): Cullin family DUF1918 (PF08940, IPR015035): Domain of unknown function (DUF1918) Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain Cul7 (PF11515, IPR021097): Mouse development and cellular proliferation protein Cullin-7
53	CWC27	interactor	5	0.500	2.900	Pro_isomerase (PF00160, IPR002130): Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF4407 (PF14362, IPR025519): Domain of unknown function (DUF4407)
54	DCAF1	protein found in more fusions	16	0.286	33.794	DUF913 (PF06025, IPR010314): Domain of Unknown Function (DUF913) LisH (PF08513, IPR013720, SM00667): LisH ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain PTPRCAP (PF15713, IPR016553): Protein tyrosine phosphatase receptor type C-associated
55	DCLRE1B	interactor	5	0.800	0.750	DRMBL (PF07522, IPR011084): DNA repair metallo-beta-lactamase Lactamase_B_2 (PF12706, IPR001279): Beta-lactamase superfamily domain
56	DCLRE1C	interactor	10	0.489	15.837	DRMBL (PF07522, IPR011084): DNA repair metallo-beta-lactamase DUF3290 (PF11694, IPR021707): Protein of unknown function (DUF3290) Lactamase_B_2 (PF12706, IPR001279): Beta-lactamase superfamily domain
57	DDA1	interactor	5	0.600	0.742	DDA1 (PF10172, IPR018276): Det1 complexing ubiquitin ligase
58	DDX5	oncoprotein	48	0.247	248.900	DEAD (PF00270, IPR011545): DEAD/DEAH box helicase P68HR (PF08061, IPR012587): P68HR (NUC004) repeat ResIII (PF04851, IPR006935): Type III restriction enzyme, res subunit Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
59	DHX38	interactor	8	0.607	3.906	DEAD (PF00270, IPR011545): DEAD/DEAH box helicase OB_NTP_bind (PF07717, IPR011709): Oligonucleotide/oligosaccharide-binding (OB)-fold DUF1764 (PF08576, IPR013885): Eukaryotic protein of unknown function (DUF1764) HA2 (PF04408, IPR007502, SM00847): Helicase associated domain (HA2) Nucleo_P87 (PF07267, IPR009893): Nucleopolyhedrovirus capsid protein P87 Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain DUF2956 (PF11169, IPR021339): Protein of unknown function (DUF2956)
60	DHX9	oncoprotein	57	0.362	269.954	DEAD (PF00270, IPR011545): DEAD/DEAH box helicase dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif OB_NTP_bind (PF07717, IPR011709): Oligonucleotide/oligosaccharide-binding (OB)-fold T2SSE (PF00437, IPR001482): Type II/IV secretion system protein HA2 (PF04408, IPR007502, SM00847): Helicase associated domain (HA2) Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
61	DNAJC7	interactor	17	0.419	27.903	DnaJ (PF00226, IPR001623, SM00271): DnaJ domain TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat Rapsyn_N (PF10579, IPR019568): Rapsyn N-terminal myristoylation and linker region ANAPC3 (PF12895): Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 (PF13414, IPR011990): TPR repeat TPR_17 (PF13431): Tetratricopeptide repeat
62	E4F1	interactor	4	0.833	0.500	FYVE (PF01363, IPR000306, SM00064): FYVE zinc finger zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_4 (PF13894): C2H2-type zinc finger zf-H2C2_5 (PF13909): C2H2-type zinc-finger domain zf-C2H2_11 (PF16622, IPR007087): zinc-finger C2H2-type
63	EED	suppressor	45	0.245	219.723	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160 ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
64	EFTUD2	interactor	39	0.312	133.227	EFG_C (PF00679, IPR000640, SM00838): Elongation factor G C-terminus EFG_IV (PF03764, IPR005517, SM00889): Elongation factor G, domain IV GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2 EFG_II (PF14492, IPR009022): Elongation Factor G, domain II EFTUD2 (PF16004, IPR031950): 116 kDa U5 small nuclear ribonucleoprotein component N-terminus
65	EGFR	oncoprotein	43	0.238	320.511	Furin-like (PF00757, IPR006211): Furin-like cysteine rich region Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase Recep_L_domain (PF01030, IPR000494): Receptor L domain GAPT (PF11770, IPR021082): GRB2-binding adapter (GAPT) GF_recep_IV (PF14843, IPR032778): Growth factor receptor domain IV
66	EHD1	interactor	8	0.524	5.068	Gp-FAR-1 (PF05823, IPR008632): Nematode fatty acid retinoid binding protein (Gp-FAR-1) Gtr1_RagA (PF04670, IPR006762): Gtr1/RagA G protein conserved region Dynamin_N (PF00350, IPR001401, SM00053): Dynamin family EF-hand_4 (PF12763, IPR000261): Cytoskeletal-regulatory complex EF hand EHD_N (PF16880, IPR031692): N-terminal EH-domain containing protein
67	EIF2S2	interactor	11	0.527	3.418	DUF1754 (PF08555, IPR013865): Eukaryotic family of unknown function (DUF1754) ETRAMP (PF09716, IPR006389): Malarial early transcribed membrane protein (ETRAMP) eIF-5_eIF-2B (PF01873, IPR002735, SM00653): Domain found in IF2B/IF5 Cytochrom_c3_2 (PF14537): Cytochrome c3
68	EIF4EBP1	oncoprotein	7	0.429	5.112	eIF_4EBP (PF05456, IPR008606): Eukaryotic translation initiation factor 4E binding protein (EIF4EBP)
69	ELAVL1	oncoprotein	55	0.202	553.305	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
70	EMD	interactor	31	0.248	156.310	LEM (PF03020, IPR003887, SM00540): LEM domain SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein
71	EP300	oncoprotein	50	0.257	361.290	Creb_binding (PF09030, IPR014744): Creb binding DUF902 (PF06001, IPR010303): Domain of Unknown Function (DUF902) Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region KIX (PF02172, IPR003101): KIX domain RR_TM4-6 (PF06459, IPR009460): Ryanodine Receptor TM 4-6 TPX2 (PF06886, IPR027329): Targeting protein for Xklp2 (TPX2) zf-TAZ (PF02135, IPR000197, SM00551): TAZ zinc finger HAT_KAT11 (PF08214, IPR013178): Histone acetylation protein Bromodomain (PF00439, IPR001487, SM00297): Bromodomain ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type
72	ERG	oncoprotein	17	0.478	15.110	Ets (PF00178, IPR000418, SM00413): Ets-domain SAM_2 (PF07647, IPR011510): SAM domain (Sterile alpha motif) SAM_PNT (PF02198, IPR003118, SM00251): Sterile alpha motif (SAM)/Pointed domain
73	ESR1	suppressor	54	0.293	339.606	Oest_recep (PF02159, IPR001292): Oestrogen receptor zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor ESR1_C (PF12743, IPR024736): Oestrogen-type nuclear receptor final C-terminal
74	FAF2	interactor	15	0.330	31.244	DUF1682 (PF07946, IPR012879): Protein of unknown function (DUF1682) UBX (PF00789, IPR001012, SM00166): UBX domain Thioredoxin_7 (PF13899): Thioredoxin-like UBA_4 (PF14555): UBA-like domain
75	FBXO6	interactor	30	0.290	102.844	FBA (PF04300, IPR007397): F-box associated region F-box-like (PF12937, IPR001810): F-box-like
76	FLII	oncoprotein	15	0.533	11.341	Gelsolin (PF00626, IPR007123): Gelsolin repeat SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal U1snRNP70_N (PF12220, IPR022023): U1 small nuclear ribonucleoprotein of 70kDa MW N terminal LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies) LRR_8 (PF13855, IPR001611): Leucine rich repeat
77	FN1	oncoprotein	41	0.306	123.211	fn1 (PF00039, IPR000083, SM00058): Fibronectin type I domain fn2 (PF00040, IPR000562, SM00059): Fibronectin type II domain fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369)
78	FOXRED2	interactor	3	1.000	0	Pyr_redox_3 (PF13738): Pyridine nucleotide-disulphide oxidoreductase
79	FZR1	suppressor	9	0.389	10.251	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
80	GBAS	interactor	4	0.833	0.143	NIPSNAP (PF07978, IPR012577): NIPSNAP
81	GRK5	protein found in more fusions	13	0.318	18.377	Pkinase (PF00069, IPR000719): Protein kinase domain RGS (PF00615, IPR000342, SM00315): Regulator of G protein signaling domain
82	GSK3A	interactor	5	0.800	0.265	Pkinase (PF00069, IPR000719): Protein kinase domain
83	GSK3B	suppressor	18	0.360	46.026	Pkinase (PF00069, IPR000719): Protein kinase domain
84	GTF2I	interactor	25	0.290	92.373	GTF2I (PF02946, IPR004212): GTF2I-like repeat
85	GZMB	interactor	5	0.600	1.280	Trypsin (PF00089, IPR001254, SM00020): Trypsin
86	H2AFX	suppressor	37	0.323	152.614	Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4 Histone_H2A_C (PF16211, IPR032454): C-terminus of histone H2A
87	H3F3A	oncoprotein	14	0.505	13.869	Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
88	HDAC11	interactor	7	0.381	6.261	Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
89	HDAC3	suppressor	26	0.347	68.729	Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
90	HDAC5	protein found in more fusions	34	0.350	76.098	Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain NOA36 (PF06524, IPR010531): NOA36 protein Activator_LAG-3 (PF11498, IPR021587): Transcriptional activator LAG-3 HDAC4_Gln (PF12203, IPR024643): Glutamine rich N terminal domain of histone deacetylase 4
91	HDGF	interactor	24	0.344	49.631	PWWP (PF00855, IPR000313, SM00293): PWWP domain
92	HDLBP	oncoprotein	17	0.456	18.915	BMC (PF00936, IPR000249, SM00877): BMC domain KH_1 (PF00013, IPR004088, SM00322): KH domain KH_4 (PF13083): KH domain KH_5 (PF13184, IPR025249): NusA-like KH domain SLS (PF14611, IPR032741): Mitochondrial inner-membrane-bound regulator DUF4530 (PF15039, IPR029202): Domain of unknown function (DUF4530)
93	HIST1H1A	interactor	12	0.364	13.689	Mucin (PF01456, IPR000458): Mucin-like glycoprotein Linker_histone (PF00538, IPR005818, SM00526): linker histone H1 and H5 family CPSF100_C (PF13299, IPR025069): Cleavage and polyadenylation factor 2 C-terminal
94	HIST1H1C	oncoprotein	18	0.373	26.489	Amelin (PF05111, IPR007798, SM00817): Ameloblastin precursor (Amelin) Linker_histone (PF00538, IPR005818, SM00526): linker histone H1 and H5 family DUF4349 (PF14257, IPR025645): Domain of unknown function (DUF4349)
95	HIST1H3A	interactor	28	0.208	156.174	Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
96	HIST1H3E	interactor	19	0.363	26.768	Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
97	HNRNPA1	interactor	63	0.344	447.025	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HnRNPA1 (PF11627, IPR021662): Nuclear factor hnRNPA1
98	HNRNPC	protein found in more fusions	39	0.434	69.795	APG6 (PF04111, IPR007243): Autophagy protein Apg6 RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SURF2 (PF05477, IPR008833): Surfeit locus protein 2 (SURF2)
99	HOXB7	interactor	4	1.000	0	Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
100	HSF1	protein found in more fusions	12	0.382	14.305	DUF247 (PF03140, IPR004158): Plant protein of unknown function Vert_HS_TF (PF06546, IPR010542): Vertebrate heat shock transcription factor HSF_DNA-bind (PF00447, IPR000232, SM00415): HSF-type DNA-binding
101	HSP90AA1	oncoprotein	66	0.202	809.052	HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HSP90 (PF00183, IPR001404): Hsp90 protein
102	HSP90AB1	oncoprotein	52	0.216	430.712	HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HSP90 (PF00183, IPR001404): Hsp90 protein
103	HSPA5	oncoprotein	52	0.307	327.488	HSP70 (PF00012, IPR013126): Hsp70 protein
104	HSPA8	oncoprotein	54	0.245	387.716	HSP70 (PF00012, IPR013126): Hsp70 protein
105	IKBKAP	interactor	15	0.374	21.272	IKI3 (PF04762, IPR006849): IKI3 family Clathrin (PF00637, IPR000547, SM00299): Region in Clathrin and VPS MMU163 (PF17119, IPR031342): Mitochondrial protein up-regulated during meiosis
106	IKBKB	protein found in more fusions	13	0.545	6.597	FliT (PF05400, IPR008622): Flagellar protein FliT Glyco_hydro_65m (PF03632, IPR005195): Glycosyl hydrolase family 65 central catalytic domain Pkinase (PF00069, IPR000719): Protein kinase domain SlyX (PF04102, IPR007236): SlyX ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family IKKbetaNEMObind (PF12179, IPR022007): I-kappa-kinase-beta NEMO binding domain
107	ILF2	interactor	43	0.434	96.545	DZF (PF07528, IPR006561, SM00572): DZF domain
108	ILF3	oncoprotein	46	0.325	208.651	dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif DZF (PF07528, IPR006561, SM00572): DZF domain
109	ILK	suppressor	19	0.392	30.171	Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_4 (PF13637): Ankyrin repeats (many copies) Ank_5 (PF13857): Ankyrin repeats (many copies)
110	IQCB1	interactor	8	0.393	2.181	DUF1765 (PF08578, IPR013887): Protein of unknown function (DUF1765) IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif HJURP_C (PF12347, IPR022102): Holliday junction regulator protein family C-terminal repeat Condensin2nSMC (PF12422, IPR024741): Condensin II non structural maintenance of chromosomes subunit
111	ITGA4	interactor	31	0.359	70.038	FG-GAP (PF01839, IPR013517): FG-GAP repeat Integrin_alpha (PF00357, IPR018184): Integrin alpha cytoplasmic region Integrin_alpha2 (PF08441, IPR013649): Integrin alpha
112	JUN	oncoprotein	27	0.378	65.146	bZIP_1 (PF00170, IPR004827): bZIP transcription factor Jun (PF03957, IPR005643): Jun-like transcription factor
113	KAT2A	interactor	12	0.600	4.123	Acetyltransf_1 (PF00583, IPR000182): Acetyltransferase (GNAT) family PCAF_N (PF06466, IPR009464): PCAF (P300/CBP-associated factor) N-terminal domain Bromodomain (PF00439, IPR001487, SM00297): Bromodomain NICE-1 (PF15845, IPR031698): Cysteine-rich C-terminal 1 family
114	KAT5	suppressor	27	0.375	57.901	MOZ_SAS (PF01853, IPR002717): MOZ/SAS family Tudor-knot (PF11717, IPR025995): RNA binding activity-knot of a chromodomain
115	KAT8	protein found in more fusions	9	0.500	6.949	MOZ_SAS (PF01853, IPR002717): MOZ/SAS family Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain) Tudor-knot (PF11717, IPR025995): RNA binding activity-knot of a chromodomain
116	LGR4	interactor	10	0.389	6.150	7tm_1 (PF00001, IPR000276): 7 transmembrane receptor (rhodopsin family) LRR_1 (PF00560, IPR001611): Leucine Rich Repeat LRRNT (PF01462, IPR000372, SM00013): Leucine rich repeat N-terminal domain LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies) LRR_8 (PF13855, IPR001611): Leucine rich repeat
117	LIG4	interactor	7	0.714	1.580	APG17 (PF04108, IPR007240): Autophagy protein Apg17 BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain DNA_ligase_A_C (PF04679, IPR012309): ATP dependent DNA ligase C terminal region DNA_ligase_A_M (PF01068, IPR012310): ATP dependent DNA ligase domain DNA_ligase_A_N (PF04675, IPR012308): DNA ligase N terminus DNA_ligase_IV (PF11411, IPR021536): DNA ligase IV RTT107_BRCT_5 (PF16770, IPR001357): Regulator of Ty1 transposition protein 107 BRCT domain
118	LMNA	protein found in more fusions	40	0.341	154.977	Filament (PF00038, IPR001664): Intermediate filament protein LTD (PF00932, IPR001322): Lamin Tail Domain Uso1_p115_C (PF04871, IPR006955): Uso1 / p115 like vesicle tethering protein, C terminal region DUF3450 (PF11932, IPR016866): Protein of unknown function (DUF3450) DUF4407 (PF14362, IPR025519): Domain of unknown function (DUF4407)
119	LRRFIP1	oncoprotein	10	0.667	5.544	CENP-H (PF05837, IPR008426): Centromere protein H (CENP-H) Rxt3 (PF08642, IPR013951): Histone deacetylation protein Rxt3 LRRFIP (PF09738, IPR019139): LRRFIP family RP-C_C (PF11800, IPR021760): Replication protein C C-terminal region Coilin_N (PF15862, IPR031722): Coilin N-terminus
120	LRRK2	oncoprotein	13	0.318	24.989	Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat ATP-synt_ab (PF00006, IPR000194): ATP synthase alpha/beta family, nucleotide-binding domain DUF1043 (PF06295, IPR009386): Protein of unknown function (DUF1043) T2SSE (PF00437, IPR001482): Type II/IV secretion system protein Roc (PF08477, IPR013684): Ras of Complex, Roc, domain of DAPkinase Pkinase (PF00069, IPR000719): Protein kinase domain Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies) PQQ_2 (PF13360, IPR002372): PQQ-like domain LRR_8 (PF13855, IPR001611): Leucine rich repeat COR (PF16095, IPR032171): C-terminal of Roc, COR, domain
121	LYN	oncoprotein	11	0.600	2.996	Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
122	MAPK8	oncoprotein	16	0.400	27.389	DUF530 (PF04409, IPR007503): Protein of unknown function (DUF530) Pkinase (PF00069, IPR000719): Protein kinase domain
123	MAPK9	suppressor	9	0.500	7.860	Pkinase (PF00069, IPR000719): Protein kinase domain Kinase-like (PF14531, IPR027916): Kinase-like
124	MBP	interactor	3	0.667	0.400	Myelin_MBP (PF01669, IPR000548): Myelin basic protein
125	MCM2	oncoprotein	56	0.294	383.409	AAA_3 (PF07726, IPR011703): ATPase family associated with various cellular activities (AAA) MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family MCM2_N (PF12619, IPR008045): Mini-chromosome maintenance protein 2 MCM_N (PF14551, IPR027925): MCM N-terminal domain MCM_OB (PF17207): MCM OB domain
126	MDC1	suppressor	36	0.313	172.710	FHA (PF00498, IPR000253, SM00240): FHA domain DUF3274 (PF11678, IPR021692): Protein of unknown function (DUF3274) Yop-YscD_cpl (PF16697, IPR032030): Inner membrane component of T3SS, cytoplasmic domain RTT107_BRCT_5 (PF16770, IPR001357): Regulator of Ty1 transposition protein 107 BRCT domain
127	METTL1	interactor	6	0.533	4.100	Methyltransf_4 (PF02390, IPR003358): Putative methyltransferase
128	MEX3C	interactor	6	0.533	0.857	KH_1 (PF00013, IPR004088, SM00322): KH domain zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
129	MGMT	interactor	13	0.577	5.355	DNA_binding_1 (PF01035, IPR014048): 6-O-methylguanine DNA methyltransferase, DNA binding domain Methyltransf_1N (PF02870, IPR008332): 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain
130	MKNK1	interactor	3	1.000	0	Pkinase (PF00069, IPR000719): Protein kinase domain
131	MLH1	suppressor	14	0.505	15.722	DNA_mis_repair (PF01119, IPR013507): DNA mismatch repair protein, C-terminal domain HATPase_c_3 (PF13589): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Mlh1_C (PF16413, IPR032189): DNA mismatch repair protein Mlh1 C-terminus
132	MRE11A	oncoprotein	41	0.315	216.929	APG6 (PF04111, IPR007243): Autophagy protein Apg6 Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase Mre11_DNA_bind (PF04152, IPR007281): Mre11 DNA-binding presumed domain
133	MSH6	oncoprotein	31	0.325	122.124	MutS_I (PF01624, IPR007695): MutS domain I MutS_II (PF05188, IPR007860): MutS domain II PWWP (PF00855, IPR000313, SM00293): PWWP domain MutS_V (PF00488, IPR000432, SM00534): MutS domain V MutS_III (PF05192, IPR007696, SM00533): MutS domain III UPF0524 (PF15823, IPR029670): UPF0524 of C3orf70
134	MSL3	interactor	3	1.000	0	GET2 (PF08690, IPR028143): GET complex subunit GET2 MRG (PF05712, IPR026541): MRG Tudor-knot (PF11717, IPR025995): RNA binding activity-knot of a chromodomain
135	MYC	oncoprotein	47	0.276	296.763	HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain Myc-LZ (PF02344, IPR003327): Myc leucine zipper domain Myc_N (PF01056, IPR012682): Myc amino-terminal region
136	NBN	suppressor	29	0.352	97.394	FHA (PF00498, IPR000253, SM00240): FHA domain Nbs1_C (PF08599, IPR013908): DNA damage repair protein Nbs1 NIBRIN_BRCT_II (PF16508, IPR032429): Second BRCT domain on Nijmegen syndrome breakage protein RTT107_BRCT_5 (PF16770, IPR001357): Regulator of Ty1 transposition protein 107 BRCT domain
137	NCF1	interactor	6	0.500	4.500	p47_phox_C (PF08944, IPR015039): NADPH oxidase subunit p47Phox, C terminal domain PX (PF00787, IPR001683, SM00312): PX domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain NECFESHC (PF16621, IPR032136): SH3 terminal domain of 2nd SH3 on Neutrophil cytosol factor 1
138	NCF2	interactor	3	1.000	0	PB1 (PF00564, IPR000270, SM00666): PB1 domain TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat SH3_1 (PF00018, IPR001452, SM00326): SH3 domain TPR_16 (PF13432): Tetratricopeptide repeat
139	NCF4	interactor	4	0.667	2.000	PX (PF00787, IPR001683, SM00312): PX domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
140	NCOA6	oncoprotein	16	0.495	18.916	DUF719 (PF05334, IPR007998): Protein of unknown function (DUF719) Fes1 (PF08609, IPR013918): Nucleotide exchange factor Fes1 Presenilin (PF01080, IPR001108): Presenilin DUF3729 (PF12526, IPR022202): Protein of unknown function (DUF3729) Nucleic_acid_bd (PF13820, IPR032715): Putative nucleic acid-binding region NST1 (PF13945, IPR025279): Salt tolerance down-regulator
141	NOS2	interactor	13	0.424	8.012	FAD_binding_1 (PF00667, IPR003097): FAD binding domain Flavodoxin_1 (PF00258, IPR008254): Flavodoxin NAD_binding_1 (PF00175, IPR001433): Oxidoreductase NAD-binding domain NO_synthase (PF02898, IPR004030): Nitric oxide synthase, oxygenase domain
142	NOTCH1	suppressor	18	0.279	35.238	Ank (PF00023, IPR002110, SM00248): Ankyrin repeat EGF (PF00008, IPR000742, SM00181): EGF-like domain EGF_2 (PF07974, IPR013111): EGF-like domain EGF_alliinase (PF04863, IPR006947): Alliinase EGF-like domain EGF_CA (PF07645, IPR001881, SM00179): Calcium-binding EGF domain NOD (PF06816, IPR010660): NOTCH protein NODP (PF07684, IPR011656): NOTCH protein TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit Notch (PF00066, IPR000800, SM00004): LNR domain DUF3454 (PF11936, IPR024600): Domain of unknown function (DUF3454) hEGF (PF12661, IPR013032): Human growth factor-like EGF cEGF (PF12662, IPR026823): Complement Clr-like EGF-like Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
143	NR1H4	interactor	7	0.810	0.939	LRV_FeS (PF05484, IPR008665): LRV protein FeS4 cluster zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
144	NR3C1	protein found in more fusions	15	0.451	12.892	GCR (PF02155, IPR001409): Glucocorticoid receptor zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
145	NTRK1	oncoprotein	87	0.184	1423.850	I-set (PF07679, IPR013098): Immunoglobulin I-set domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase LRR_8 (PF13855, IPR001611): Leucine rich repeat TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain
146	NUCB1	interactor	6	0.600	2.630	DUF1104 (PF06518, IPR009488): Protein of unknown function (DUF1104) Spc24 (PF08286, IPR013252): Spc24 subunit of Ndc80 DUF2967 (PF11179, IPR021349): Protein of unknown function (DUF2967) DUF3552 (PF12072, IPR022711): Domain of unknown function (DUF3552) EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
147	NUP107	interactor	14	0.538	9.910	Nup84_Nup100 (PF04121, IPR007252): Nuclear pore protein 84 / 107
148	NUP35	interactor	8	0.679	1.821	Nup35_RRM (PF05172, IPR007846): Nup53/35/40-type RNA recognition motif
149	NUP85	interactor	12	0.439	14.955	Nucleopor_Nup85 (PF07575, IPR011502): Nup85 Nucleoporin
150	OBSL1	interactor	48	0.314	196.393	BiPBP_C (PF06832, IPR009647): Penicillin-Binding Protein C-terminus Family fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain Herpes_gE (PF02480, IPR003404): Alphaherpesvirus glycoprotein E I-set (PF07679, IPR013098): Immunoglobulin I-set domain V-set (PF07686, IPR013106): Immunoglobulin V-set domain Ig_3 (PF13927): Immunoglobulin domain Ig_4 (PF16680, IPR032052): T-cell surface glycoprotein CD3 delta chain Izumo-Ig (PF16706, IPR032699): Izumo-like Immunoglobulin domain
151	PAN2	interactor	24	0.315	50.502	RNase_T (PF00929, IPR013520): Exonuclease UCH_1 (PF13423, IPR001394): Ubiquitin carboxyl-terminal hydrolase WD40_like (PF17005, IPR031544): WD40-like domain
152	PARP1	suppressor	60	0.214	552.284	BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain PADR1 (PF08063, IPR012982): PADR1 (NUC008) domain PARP (PF00644, IPR012317): Poly(ADP-ribose) polymerase catalytic domain PARP_reg (PF02877, IPR004102): Poly(ADP-ribose) polymerase, regulatory domain WGR (PF05406, IPR008893, SM00773): WGR domain zf-PARP (PF00645, IPR001510): Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region
153	PCNA	oncoprotein	45	0.254	285.757	PCNA_C (PF02747, IPR022649): Proliferating cell nuclear antigen, C-terminal domain PCNA_N (PF00705, IPR022648): Proliferating cell nuclear antigen, N-terminal domain
154	PDX1	suppressor	3	1.000	0	CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal Homeobox (PF00046, IPR001356, SM00389): Homeobox domain TMEM171 (PF15471, IPR029173): Transmembrane protein family 171
155	PGR	suppressor	14	0.679	5.442	Prog_receptor (PF02161, IPR000128): Progesterone receptor zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
156	PHGDH	interactor	23	0.356	40.353	2-Hacid_dh_C (PF02826, IPR006140): D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
157	PHKG2	interactor	3	1.000	0	APH (PF01636, IPR002575): Phosphotransferase enzyme family Pkinase (PF00069, IPR000719): Protein kinase domain
158	PIDD1	interactor	5	0.400	2.344	Death (PF00531, IPR000488, SM00005): Death domain ZU5 (PF00791, IPR000906, SM00218): ZU5 domain Peptidase_S68 (PF10461, IPR019502): Peptidase S68 LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies) LRR_8 (PF13855, IPR001611): Leucine rich repeat
159	PINK1	protein found in more fusions	5	1.000	0	Pkinase (PF00069, IPR000719): Protein kinase domain
160	PMS2	oncoprotein	9	0.528	3.813	DNA_mis_repair (PF01119, IPR013507): DNA mismatch repair protein, C-terminal domain MORN_2 (PF07661, IPR011652): MORN repeat variant MutL_C (PF08676, IPR014790, SM00853): MutL C terminal dimerisation domain HATPase_c_3 (PF13589): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
161	PNKP	interactor	13	0.513	12.852	PNK3P (PF08645, IPR013954): Polynucleotide kinase 3 phosphatase AAA_33 (PF13671): AAA domain
162	POT1	interactor	9	0.643	3.896	POT1 (PF02765, IPR011564, SM00976): Telomeric single stranded DNA binding POT1/CDC13 tRNA_anti-codon (PF01336, IPR004365): OB-fold nucleic acid binding domain POT1PC (PF16686, IPR032042): ssDNA-binding domain of telomere protection protein
163	POU2F1	protein found in more fusions	14	0.615	6.845	Pou (PF00157, IPR000327, SM00352): Pou domain - N-terminal to homeobox domain Homeobox (PF00046, IPR001356, SM00389): Homeobox domain DUF3597 (PF12200, IPR022016): Domain of unknown function (DUF3597)
164	POU5F1	oncoprotein	18	0.279	45.414	Pou (PF00157, IPR000327, SM00352): Pou domain - N-terminal to homeobox domain Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
165	PPP2CA	suppressor	28	0.235	110.962	Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase STPPase_N (PF16891, IPR031675): Serine-threonine protein phosphatase N-terminal domain
166	PPP6C	interactor	14	0.330	32.005	Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase
167	PPP6R1	interactor	11	0.473	15.954	CENP-B_dimeris (PF09026, IPR015115): Centromere protein B dimerisation domain SAPS (PF04499, IPR007587): SIT4 phosphatase-associated protein WRNPLPNID (PF15017): Putative WW-binding domain and destruction box
168	PPP6R2	interactor	7	0.619	4.600	SAMP (PF05924, IPR009224): SAMP Motif SAPS (PF04499, IPR007587): SIT4 phosphatase-associated protein
169	PPP6R3	interactor	15	0.343	36.322	SAPS (PF04499, IPR007587): SIT4 phosphatase-associated protein
170	PRDX1	oncoprotein	32	0.258	127.441	AhpC-TSA (PF00578, IPR000866): AhpC/TSA family 1-cysPrx_C (PF10417, IPR019479): C-terminal domain of 1-Cys peroxiredoxin
171	PRKAB2	interactor	3	1.000	0	AMPKBI (PF04739, IPR006828, SM01010): 5'-AMP-activated protein kinase beta subunit, interaction domain AMPK1_CBM (PF16561, IPR032640): Glycogen recognition site of AMP-activated protein kinase
172	PRPF8	oncoprotein	36	0.336	98.443	PRO8NT (PF08082, IPR012591): PRO8NT (NUC069), PrP8 N-terminal domain PROCN (PF08083, IPR012592): PROCN (NUC071) domain PROCT (PF08084, IPR012984): PROCT (NUC072) domain RRM_4 (PF10598, IPR019582): RNA recognition motif of the spliceosomal PrP8 U5_2-snRNA_bdg (PF10597, IPR019581): U5-snRNA binding site 2 of PrP8 U6-snRNA_bdg (PF10596, IPR019580): U6-snRNA interacting domain of PrP8 JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease PRP8_domainIV (PF12134, IPR021983): PRP8 domain IV core
173	PTER	interactor	3	1.000	0	PTE (PF02126, IPR001559): Phosphotriesterase family
174	RAD17	interactor	4	0.667	0.686	Mvb12 (PF09452, IPR019014): ESCRT-I subunit Mvb12 Rad17 (PF03215): Rad17 cell cycle checkpoint protein
175	RAD21	oncoprotein	23	0.372	36.209	Rad21_Rec8 (PF04824, IPR006909): Conserved region of Rad21 / Rec8 like protein Rad21_Rec8_N (PF04825, IPR006910): N terminus of Rad21 / Rec8 like protein FAM176 (PF14851): FAM176 family WRNPLPNID (PF15017): Putative WW-binding domain and destruction box
176	RANBP2	oncoprotein	29	0.349	97.214	Pro_isomerase (PF00160, IPR002130): Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat Ran_BP1 (PF00638, IPR000156, SM00160): RanBP1 domain zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others DUF2693 (PF10902, IPR024401): Protein of unknown function (DUF2693) IR1-M (PF12185, IPR022011): Nup358/RanBP2 E3 ligase domain Dmrt1 (PF12374, IPR022114): Double-sex mab3 related transcription factor 1 TPR_9 (PF13371, IPR011990): Tetratricopeptide repeat TPR_11 (PF13414, IPR011990): TPR repeat TPR_12 (PF13424): Tetratricopeptide repeat TPR_19 (PF14559): Tetratricopeptide repeat
177	RASSF1	suppressor	5	0.667	1.000	RA (PF00788, IPR000159, SM00314): Ras association (RalGDS/AF-6) domain C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain) Nore1-SARAH (PF16517, IPR011524): Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain
178	RBBP8	suppressor	8	0.619	2.970	ZapB (PF06005, IPR009252): Cell division protein ZapB Exonuc_VII_L (PF02601, IPR020579): Exonuclease VII, large subunit SAE2 (PF08573, IPR013882): DNA repair protein endonuclease SAE2/CtIP C-terminus CtIP_N (PF10482, IPR019518): Tumour-suppressor protein CtIP N-terminal domain DUF4446 (PF14584, IPR027981): Protein of unknown function (DUF4446)
179	RBM25	interactor	16	0.300	17.898	Vfa1 (PF08432, IPR013640): AAA-ATPase Vps4-associated protein 1 PWI (PF01480, IPR002483, SM00311): PWI domain RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SMN (PF06003, IPR010304): Survival motor neuron protein (SMN) SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal MIP-T3 (PF10243): Microtubule-binding protein MIP-T3 DUF3441 (PF11923, IPR021846): Domain of unknown function (DUF3441) U1snRNP70_N (PF12220, IPR022023): U1 small nuclear ribonucleoprotein of 70kDa MW N terminal DUF4778 (PF16008, IPR031958): Domain of unknown function (DUF4778)
180	RECQL5	oncoprotein	9	0.556	3.927	DEAD (PF00270, IPR011545): DEAD/DEAH box helicase RecQ5 (PF06959, IPR010716): RecQ helicase protein-like 5 (RecQ5) SRI (PF08236, IPR013257): SRI (Set2 Rpb1 interacting) domain TFIIS_M (PF07500, IPR003618): Transcription factor S-II (TFIIS), central domain Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain RecQ_Zn_bind (PF16124, IPR032284): RecQ zinc-binding TAtT (PF16811, IPR031823): TRAP transporter T-component
181	RELA	oncoprotein	34	0.318	143.428	DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region RHD_DNA_bind (PF00554, IPR011539): Rel homology DNA-binding domain RHD_dimer (PF16179, IPR032397): Rel homology dimerisation domain
182	RFC2	interactor	21	0.367	48.976	AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA) Rep_fac_C (PF08542, IPR013748): Replication factor C C-terminal domain AAA_16 (PF13191): AAA ATPase domain AAA_assoc_2 (PF16193, IPR032423): AAA C-terminal domain
183	RNF144A	suppressor	2	0	0	IBR (PF01485, IPR002867, SM00647): IBR domain, a half RING-finger domain zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain
184	RPA1	suppressor	59	0.301	413.530	Rep-A_N (PF04057, IPR007199): Replication factor-A protein 1, N-terminal domain Rep_fac-A_C (PF08646, IPR013955): Replication factor-A C terminal domain tRNA_anti-codon (PF01336, IPR004365): OB-fold nucleic acid binding domain REPA_OB_2 (PF16900, IPR031657): Replication protein A OB domain
185	RPA2	oncoprotein	44	0.331	161.395	RPA_C (PF08784, IPR014892): Replication protein A C terminal tRNA_anti-codon (PF01336, IPR004365): OB-fold nucleic acid binding domain RMI2 (PF16100, IPR032245): RecQ-mediated genome instability protein 2
186	RPA3	interactor	40	0.335	111.287	Rep_fac-A_3 (PF08661, IPR013970): Replication factor A protein 3
187	RPS11	interactor	17	0.397	12.675	Ribosomal_S17 (PF00366, IPR000266): Ribosomal protein S17 Ribosomal_S17_N (PF16205, IPR032440): Ribosomal_S17 N-terminal
188	RTCB	interactor	24	0.460	41.736	RtcB (PF01139, IPR001233): tRNA-splicing ligase RtcB
189	RUVBL1	oncoprotein	41	0.227	248.744	TIP49 (PF06068, IPR010339): TIP49 C-terminus
190	RYK	oncoprotein	6	0.667	3.143	Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase WIF (PF02019, IPR003306, SM00469): WIF domain
191	SAP25	interactor	2	1.000	0	SAP25 (PF15476, IPR029163): Histone deacetylase complex subunit SAP25
192	SCARNA22	interactor	16	0.475	8.302	NA
193	SF3B6	interactor	18	0.536	20.032	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
194	SHC1	oncoprotein	18	0.500	16.605	PID (PF00640, IPR006020, SM00462): Phosphotyrosine interaction domain (PTB/PID) SH2 (PF00017, IPR000980, SM00252): SH2 domain
195	SIRT6	suppressor	13	0.295	10.734	SIR2 (PF02146, IPR003000): Sir2 family TPP_enzyme_M (PF00205, IPR012000): Thiamine pyrophosphate enzyme, central domain
196	SIRT7	interactor	34	0.275	134.701	DUF563 (PF04577, IPR007657): Protein of unknown function (DUF563) SIR2 (PF02146, IPR003000): Sir2 family
197	SKI	oncoprotein	16	0.448	14.782	c-SKI_SMAD_bind (PF08782, IPR014890, SM01046): c-SKI Smad4 binding domain Ski_Sno (PF02437, IPR003380): SKI/SNO/DAC family SlyX (PF04102, IPR007236): SlyX HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1
198	SMARCA5	interactor	30	0.352	62.117	HAND (PF09110, IPR015194): HAND SLIDE (PF09111, IPR015195): SLIDE SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain DUF4200 (PF13863, IPR025252): Domain of unknown function (DUF4200) DBINO (PF13892, IPR020838): DNA-binding domain RCDG1 (PF15725, IPR031457): Renal cancer differentiation gene 1 protein
199	SMARCAD1	interactor	19	0.485	19.145	CUE (PF02845, IPR003892, SM00546): CUE domain Pox_D5 (PF03288, IPR004968): Poxvirus D5 protein-like SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
200	SNRPA	interactor	13	0.530	2.539	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
201	SNW1	protein found in more fusions	55	0.275	404.241	SKIP_SNW (PF02731, IPR004015): SKIP/SNW domain PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term SIR4_SID (PF16991, IPR031556): Sir4 SID domain
202	SP1	protein found in more fusions	22	0.505	35.352	zf-Di19 (PF05605, IPR008598): Drought induced 19 protein (Di19), zinc-binding Herpes_capsid (PF06112, IPR009299): Gammaherpesvirus capsid protein zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type Miga (PF10265, IPR019392): Mitoguardin zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
203	SRF	interactor	10	0.528	4.170	SRF-TF (PF00319, IPR002100, SM00432): SRF-type transcription factor (DNA-binding and dimerisation domain)
204	SRP14	interactor	12	0.394	10.455	SRP14 (PF02290, IPR003210): Signal recognition particle 14kD protein
205	SRP54	interactor	8	0.571	3.838	5_3_exonuc (PF01367, IPR020045, SM00475): 5'-3' exonuclease, C-terminal SAM fold ResIII (PF04851, IPR006935): Type III restriction enzyme, res subunit SRP54 (PF00448, IPR000897, SM00962): SRP54-type protein, GTPase domain SRP54_N (PF02881, IPR013822, SM00963): SRP54-type protein, helical bundle domain SRP_SPB (PF02978, IPR004125): Signal peptide binding domain YlbD_coat (PF14071, IPR025953): Putative coat protein
206	SRSF10	interactor	12	0.515	8.445	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
207	STAU1	protein found in more fusions	31	0.409	76.759	dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif Staufen_C (PF16482, IPR032478): Staufen C-terminal domain
208	SUMO2	interactor	19	0.373	25.469	Rad60-SLD (PF11976, IPR022617): Ubiquitin-2 like Rad60 SUMO-like
209	TELO2	interactor	9	0.472	11.116	Telomere_reg-2 (PF10193, IPR019337): Telomere length regulation protein HEAT_2 (PF13646): HEAT repeats
210	TERF1	interactor	20	0.339	51.445	TRF (PF08558, IPR013867): Telomere repeat binding factor (TRF) Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
211	THOC6	interactor	10	0.578	5.790	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 (PF16529, IPR032401): WD40 region of Ge1, enhancer of mRNA-decapping protein
212	THRA	suppressor	13	0.485	13.344	C1_2 (PF03107, IPR004146): C1 domain zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
213	THRB	suppressor	10	0.556	6.335	zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
214	THYN1	interactor	2	1.000	0	EVE (PF01878, IPR002740): EVE domain
215	TINF2	interactor	12	0.436	15.994	TINF2_N (PF14973, IPR029400): TERF1-interacting nuclear factor 2 N-terminus
216	TP53	suppressor	71	0.222	852.877	DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region P53 (PF00870, IPR011615): P53 DNA-binding domain P53_tetramer (PF07710, IPR010991): P53 tetramerisation motif
217	TPR	oncoprotein	24	0.373	58.643	Baculo_PEP_C (PF04513, IPR007601): Baculovirus polyhedron envelope protein, PEP, C terminus ZapB (PF06005, IPR009252): Cell division protein ZapB Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family IncA (PF04156, IPR007285): IncA protein Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein Seryl_tRNA_N (PF02403, IPR015866): Seryl-tRNA synthetase N-terminal domain TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein Jnk-SapK_ap_N (PF09744, IPR019143): JNK_SAPK-associated protein-1 XhlA (PF10779, IPR019715): Haemolysin XhlA ADIP (PF11559, IPR021622): Afadin- and alpha -actinin-Binding Alanine_zipper (PF11839, IPR021793): Alanine-zipper, major outer membrane lipoprotein DUF3373 (PF11853, IPR021803): Protein of unknown function (DUF3373) DUF4107 (PF13389, IPR025180): Protein of unknown function (DUF4107) JIP_LZII (PF16471, IPR032486): JNK-interacting protein leucine zipper II CREPT (PF16566, IPR032337): Cell-cycle alteration and expression-elevated protein in tumour DUF5082 (PF16888, IPR031681): Domain of unknown function (DUF5082)
218	TRA2B	interactor	16	0.525	18.648	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Transformer (PF06495, IPR010519): Fruit fly transformer protein
219	TTI1	interactor	9	0.528	6.719	Dopey_N (PF04118, IPR007249): Dopey, N-terminal HEAT (PF02985, IPR000357): HEAT repeat VHS (PF00790, IPR002014, SM00288): VHS domain CLASP_N (PF12348, IPR024395): CLASP N terminal
220	TTI2	interactor	7	0.619	2.132	Tti2 (PF10521, IPR018870): Tti2 family
221	U2AF2	protein found in more fusions	43	0.413	128.675	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Transformer (PF06495, IPR010519): Fruit fly transformer protein
222	UBAC2	interactor	4	0.667	1.333	Rhomboid (PF01694, IPR022764): Rhomboid family UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
223	UBE2I	interactor	38	0.272	203.640	UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
224	UBXN6	interactor	6	0.533	3.800	PUB (PF09409, IPR018997): PUB domain UBX (PF00789, IPR001012, SM00166): UBX domain
225	USF1	oncoprotein	10	0.472	5.270	HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain Rootletin (PF15035): Ciliary rootlet component, centrosome cohesion
226	VCAM1	interactor	25	0.373	28.869	C2-set (PF05790, IPR008424): Immunoglobulin C2-set domain I-set (PF07679, IPR013098): Immunoglobulin I-set domain ig (PF00047, IPR013151, SM00409): Immunoglobulin domain V-set (PF07686, IPR013106): Immunoglobulin V-set domain Ig_3 (PF13927): Immunoglobulin domain
227	WRN	oncoprotein	22	0.519	31.937	DNA_pol_A_exo1 (PF01612, IPR002562, SM00474): 3'-5' exonuclease DEAD (PF00270, IPR011545): DEAD/DEAH box helicase HRDC (PF00570, IPR002121, SM00341): HRDC domain Laminin_II (PF06009, IPR010307): Laminin Domain II RQC (PF09382, IPR018982, SM00956): RQC domain Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain HTH_40 (PF14493, IPR029491): Helix-turn-helix domain RecQ_Zn_bind (PF16124, IPR032284): RecQ zinc-binding
228	XPA	oncoprotein	5	0.700	0.372	XPA_C (PF05181, IPR022656): XPA protein C-terminus XPA_N (PF01286, IPR022652): XPA protein N-terminal MscS_TM (PF12794, IPR025692): Mechanosensitive ion channel inner membrane domain 1 zinc_ribbon_2 (PF13240, IPR026870): zinc-ribbon domain
229	XRCC4	interactor	12	0.400	17.376	XRCC4 (PF06632, IPR010585): DNA double-strand break repair and V(D)J recombination protein XRCC4
230	XRCC5	suppressor	76	0.189	991.591	Ku (PF02735, IPR006164, SM00559): Ku70/Ku80 beta-barrel domain Ku_C (PF03730, IPR005160): Ku70/Ku80 C-terminal arm Ku_N (PF03731, IPR005161): Ku70/Ku80 N-terminal alpha/beta domain Ku_PK_bind (PF08785, IPR014893): Ku C terminal domain like
231	XRCC6	oncoprotein	80	0.204	1095.534	Ku (PF02735, IPR006164, SM00559): Ku70/Ku80 beta-barrel domain Ku_C (PF03730, IPR005160): Ku70/Ku80 C-terminal arm Ku_N (PF03731, IPR005161): Ku70/Ku80 N-terminal alpha/beta domain SAP (PF02037, IPR003034, SM00513): SAP domain
232	YBX1	oncoprotein	31	0.312	88.234	CSD (PF00313, IPR002059): 'Cold-shock' DNA-binding domain PBP1_TM (PF14812, IPR032730): Transmembrane domain of transglycosylase PBP1 at N-terminal FXR_C1 (PF16096, IPR032172): Fragile X-related 1 protein C-terminal region 2
233	YWHAQ	interactor	38	0.279	176.330	14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
234	YY1	protein found in more fusions	20	0.439	22.630	zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_4 (PF13894): C2H2-type zinc finger Keratin_2_tail (PF16210, IPR032449): Keratin type II cytoskeletal 1 tail

B a c k    t o    T o p ⇑