1 |
PRKDC | parental protein | 234 | 0.084 | 28337.733 | FAT (PF02259, IPR003151): FAT domain FATC (PF02260, IPR003152): FATC domain NUC194 (PF08163, IPR012582): NUC194 domain PI3_PI4_kinase (PF00454, IPR000403, SM00146): Phosphatidylinositol 3- and 4-kinase |
2 |
ABL1 | oncoprotein | 21 | 0.400 | 38.135 | Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain F_actin_bind (PF08919, IPR015015, SM00808): F-actin binding SH3_1 (PF00018, IPR001452, SM00326): SH3 domain FRG2 (PF15315, IPR026245): Facioscapulohumeral muscular dystrophy candidate 2 |
3 |
ADRB2 | interactor | 4 | 0.667 | 0.154 | 7tm_1 (PF00001, IPR000276): 7 transmembrane receptor (rhodopsin family) |
4 |
AICDA | interactor | 6 | 0.600 | 0.560 | APOBEC_N (PF08210, IPR013158): APOBEC-like N-terminal domain |
5 |
AIRE | interactor | 14 | 0.359 | 8.649 | PHD (PF00628, IPR019787, SM00249): PHD-finger SAND (PF01342, IPR000770, SM00258): SAND domain HSR (PF03172, IPR004865): HSR domain; Sp100 domain zf-PHD-like (PF15446): PHD/FYVE-zinc-finger like domain |
6 |
AKT1 | oncoprotein | 30 | 0.271 | 149.912 | PH (PF00169, IPR001849, SM00233): PH domain Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain |
7 |
AKT2 | oncoprotein | 10 | 0.400 | 13.323 | PH (PF00169, IPR001849, SM00233): PH domain Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain |
8 |
ALOX15 | suppressor | 1 | 0 | 0 | Lipoxygenase (PF00305, IPR013819): Lipoxygenase PLAT (PF01477, IPR001024, SM00308): PLAT/LH2 domain |
9 |
ANAPC2 | interactor | 8 | 0.536 | 4.042 | ANAPC2 (PF08672, IPR014786, SM01013): Anaphase promoting complex (APC) subunit 2 Cullin (PF00888, IPR001373, SM00182): Cullin family |
10 |
AP1B1 | interactor | 15 | 0.476 | 12.922 | Adaptin_N (PF01602, IPR002553): Adaptin N terminal region Alpha_adaptinC2 (PF02883, IPR008152, SM00809): Adaptin C-terminal domain B2-adapt-app_C (PF09066, IPR015151, SM01020): Beta2-adaptin appendage, C-terminal sub-domain |
11 |
AP2M1 | protein found in more fusions | 17 | 0.325 | 34.802 | Adap_comp_sub (PF00928, IPR008968): Adaptor complexes medium subunit family Clat_adaptor_s (PF01217, IPR022775): Clathrin adaptor complex small chain |
12 |
AR | oncoprotein | 27 | 0.345 | 66.842 | Androgen_recep (PF02166, IPR001103): Androgen receptor zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor |
13 |
ARHGEF6 | oncoprotein | 2 | 0 | 0 | CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain Cnn_1N (PF07989, IPR012943): Centrosomin N-terminal motif 1 PH (PF00169, IPR001849, SM00233): PH domain RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain SH3_9 (PF14604, IPR001452): Variant SH3 domain betaPIX_CC (PF16523, IPR032409): betaPIX coiled coil RhoGEF67_u2 (PF16614): Unstructured region two on RhoGEF 6 and 7 RhoGEF67_u1 (PF16615): Unstructured region one on RhoGEF 6 and 7 |
14 |
ASB5 | interactor | 2 | 1.000 | 0 | Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_5 (PF13857): Ankyrin repeats (many copies) SOCS_box (PF07525, IPR001496): SOCS box |
15 |
ATG101 | interactor | 3 | 0.667 | 0.286 | ATG101 (PF07855, IPR012445): Autophagy-related protein 101 |
16 |
ATG4C | interactor | 1 | 0 | 0 | Peptidase_C54 (PF03416, IPR005078): Peptidase family C54 |
17 |
ATM | suppressor | 41 | 0.241 | 330.881 | FAT (PF02259, IPR003151): FAT domain FATC (PF02260, IPR003152): FATC domain HEAT (PF02985, IPR000357): HEAT repeat PI3_PI4_kinase (PF00454, IPR000403, SM00146): Phosphatidylinositol 3- and 4-kinase TAN (PF11640, IPR021668): Telomere-length maintenance and DNA damage repair ANAPC5 (PF12862, IPR026000): Anaphase-promoting complex subunit 5 |
18 |
ATRIP | interactor | 8 | 0.821 | 0.619 | Tropomyosin_1 (PF12718, IPR000533): Tropomyosin like |
19 |
ATRX | oncoprotein | 14 | 0.495 | 15.567 | DDHD (PF02862, IPR004177, SM01127): DDHD domain DTHCT (PF08070, IPR012542): DTHCT (NUC029) region Pap_E4 (PF02711, IPR003861): E4 protein PHD (PF00628, IPR019787, SM00249): PHD-finger Secretin_N_2 (PF07655, IPR011514): Secretin N-terminal domain SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain Zip (PF02535, IPR003689): ZIP Zinc transporter DUF2052 (PF09747, IPR018613): Coiled-coil domain containing protein (DUF2052) Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain DUF2992 (PF11208, IPR016787): Protein of unknown function (DUF2992) DUF3408 (PF11888, IPR021823): Protein of unknown function (DUF3408) PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term SEEEED (PF14797, IPR029394): Serine-rich region of AP3B1, clathrin-adaptor complex FAM176 (PF14851): FAM176 family DUF4746 (PF15928, IPR031827): Domain of unknown function (DUF4746) |
20 |
AUP1 | interactor | 7 | 0.381 | 4.474 | CUE (PF02845, IPR003892, SM00546): CUE domain |
21 |
BAG3 | oncoprotein | 19 | 0.222 | 78.783 | BAG (PF02179, IPR003103, SM00264): BAG domain WW (PF00397, IPR001202, SM00456): WW domain |
22 |
BECN1 | suppressor | 7 | 0.533 | 2.938 | APG6 (PF04111, IPR007243): Autophagy protein Apg6 Ima1_N (PF09779, IPR018617): Ima1 N-terminal domain BH3 (PF15285, IPR029318): Beclin-1 BH3 domain, Bcl-2-interacting |
23 |
BIRC5 | interactor | 10 | 0.556 | 4.514 | BIR (PF00653, IPR001370, SM00238): Inhibitor of Apoptosis domain |
24 |
BMI1 | oncoprotein | 29 | 0.333 | 66.753 | zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger) RAWUL (PF16207, IPR032443): RAWUL domain RING finger- and WD40-associated ubiquitin-like |
25 |
BRCA1 | suppressor | 58 | 0.249 | 528.114 | BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger) BRCT_assoc (PF12820, IPR025994): Serine-rich domain associated with BRCT |
26 |
C14orf166 | interactor | 23 | 0.494 | 36.727 | RLL (PF10036, IPR019265): Putative carnitine deficiency-associated protein |
27 |
C1D | interactor | 3 | 0.667 | 0.250 | Sas10_Utp3 (PF04000, IPR007146): Sas10/Utp3/C1D family |
28 |
CAMKK2 | oncoprotein | 3 | 0.667 | 0.143 | Pkinase (PF00069, IPR000719): Protein kinase domain |
29 |
CASP3 | interactor | 14 | 0.308 | 32.155 | Peptidase_C14 (PF00656, IPR011600): Caspase domain |
30 |
CCDC8 | interactor | 39 | 0.317 | 107.851 | Borrelia_P83 (PF05262, IPR007926): Borrelia P83/100 protein SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal PNMA (PF14893, IPR026523): PNMA |
31 |
CCNB1 | oncoprotein | 14 | 0.451 | 15.852 | Adeno_E1A (PF02703, IPR003853): Early E1A protein Cyclin_C (PF02984, IPR004367): Cyclin, C-terminal domain Cyclin_N (PF00134, IPR006671): Cyclin, N-terminal domain |
32 |
CDC5L | interactor | 65 | 0.282 | 503.388 | OmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like) Pox_A_type_inc (PF04508, IPR007596): Viral A-type inclusion protein repeat Cir_N (PF10197, IPR019339, SM01083): N-terminal domain of CBF1 interacting co-repressor CIR Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain Myb_Cef (PF11831, IPR021786): pre-mRNA splicing factor component Myb_DNA-bind_6 (PF13921): Myb-like DNA-binding domain |
33 |
CDK2 | suppressor | 50 | 0.304 | 286.803 | Kdo (PF06293, IPR010440): Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase (PF00069, IPR000719): Protein kinase domain |
34 |
CENPA | interactor | 16 | 0.419 | 15.888 | Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4 |
35 |
CFTR | suppressor | 9 | 0.357 | 6.513 | ABC_membrane (PF00664, IPR001140): ABC transporter transmembrane region ABC_tran (PF00005, IPR003439): ABC transporter Roc (PF08477, IPR013684): Ras of Complex, Roc, domain of DAPkinase SMC_N (PF02463, IPR003395): RecF/RecN/SMC N terminal domain Rotamase_2 (PF13145, IPR000297): PPIC-type PPIASE domain CFTR_R (PF14396, IPR025837): Cystic fibrosis TM conductance regulator (CFTR), regulator domain |
36 |
CHAF1A | interactor | 16 | 0.438 | 21.459 | CAF-1_p150 (PF11600): Chromatin assembly factor 1 complex p150 subunit, N-terminal CAF1A (PF12253, IPR022043): Chromatin assembly factor 1 subunit A CAF1-p150_C2 (PF15539, IPR029105): CAF1 complex subunit p150, region binding to CAF1-p60 at C-term CAF1-p150_N (PF15557, IPR029091): CAF1 complex subunit p150, region binding to PCNA |
37 |
CHD1L | interactor | 13 | 0.615 | 8.164 | ATP-synt_E (PF05680, IPR008386): ATP synthase E chain SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain |
38 |
CHEK1 | suppressor | 14 | 0.615 | 4.577 | Pkinase (PF00069, IPR000719): Protein kinase domain |
39 |
CHEK2 | suppressor | 8 | 0.810 | 0.672 | FHA (PF00498, IPR000253, SM00240): FHA domain Pkinase (PF00069, IPR000719): Protein kinase domain |
40 |
CHUK | suppressor | 19 | 0.523 | 19.486 | Pkinase (PF00069, IPR000719): Protein kinase domain IKKbetaNEMObind (PF12179, IPR022007): I-kappa-kinase-beta NEMO binding domain |
41 |
CIB1 | interactor | 1 | 0 | 0 | EF-hand_7 (PF13499, IPR011992): EF-hand domain pair |
42 |
CLK1 | interactor | 8 | 0.476 | 6.237 | PDGF_N (PF04692, IPR006782): Platelet-derived growth factor, N terminal region Pkinase (PF00069, IPR000719): Protein kinase domain |
43 |
CLN3 | interactor | 6 | 0.333 | 3.552 | CLN3 (PF02487, IPR003492): CLN3 protein |
44 |
COPS5 | protein found in more fusions | 49 | 0.298 | 277.374 | JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease |
45 |
CRY1 | interactor | 11 | 0.311 | 6.326 | DNA_photolyase (PF00875, IPR006050): DNA photolyase FAD_binding_7 (PF03441, IPR005101): FAD binding domain of DNA photolyase |
46 |
CRY2 | protein found in more fusions | 14 | 0.359 | 13.740 | DNA_photolyase (PF00875, IPR006050): DNA photolyase FAD_binding_7 (PF03441, IPR005101): FAD binding domain of DNA photolyase |
47 |
CSNK2A1 | oncoprotein | 39 | 0.304 | 192.838 | Pkinase (PF00069, IPR000719): Protein kinase domain |
48 |
CTDP1 | interactor | 4 | 0.500 | 1.582 | Biotin_lipoyl (PF00364, IPR000089): Biotin-requiring enzyme FCP1_C (PF09309, IPR015388): FCP1, C-terminal NIF (PF03031, IPR004274): NLI interacting factor-like phosphatase SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal Apt1 (PF10351, IPR019443): Golgi-body localisation protein domain TFIIE-A_C (PF11521, IPR021600): C-terminal general transcription factor TFIIE alpha CAF1A (PF12253, IPR022043): Chromatin assembly factor 1 subunit A PTCB-BRCT (PF12738, IPR001357): twin BRCT domain HlyD_D23 (PF16576, IPR032317): Barrel-sandwich domain of CusB or HlyD membrane-fusion |
49 |
CTPS2 | protein found in more fusions | 8 | 0.524 | 7.352 | CTP_synth_N (PF06418, IPR017456): CTP synthase N-terminus GATase (PF00117, IPR017926): Glutamine amidotransferase class-I |
50 |
CUL3 | protein found in more fusions | 58 | 0.262 | 410.216 | Cullin (PF00888, IPR001373, SM00182): Cullin family Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain WAC_Acf1_DNA_bd (PF10537, IPR013136): ATP-utilising chromatin assembly and remodelling N-terminal |
51 |
CUL5 | suppressor | 33 | 0.347 | 114.837 | Cullin (PF00888, IPR001373, SM00182): Cullin family GlutR_dimer (PF00745, IPR015896): Glutamyl-tRNAGlu reductase, dimerisation domain Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain |
52 |
CUL7 | protein found in more fusions | 48 | 0.354 | 154.222 | ANAPC10 (PF03256, IPR004939): Anaphase-promoting complex, subunit 10 (APC10) Cullin (PF00888, IPR001373, SM00182): Cullin family DUF1918 (PF08940, IPR015035): Domain of unknown function (DUF1918) Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain Cul7 (PF11515, IPR021097): Mouse development and cellular proliferation protein Cullin-7 |
53 |
CWC27 | interactor | 5 | 0.500 | 2.900 | Pro_isomerase (PF00160, IPR002130): Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF4407 (PF14362, IPR025519): Domain of unknown function (DUF4407) |
54 |
DCAF1 | protein found in more fusions | 16 | 0.286 | 33.794 | DUF913 (PF06025, IPR010314): Domain of Unknown Function (DUF913) LisH (PF08513, IPR013720, SM00667): LisH ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain PTPRCAP (PF15713, IPR016553): Protein tyrosine phosphatase receptor type C-associated |
55 |
DCLRE1B | interactor | 5 | 0.800 | 0.750 | DRMBL (PF07522, IPR011084): DNA repair metallo-beta-lactamase Lactamase_B_2 (PF12706, IPR001279): Beta-lactamase superfamily domain |
56 |
DCLRE1C | interactor | 10 | 0.489 | 15.837 | DRMBL (PF07522, IPR011084): DNA repair metallo-beta-lactamase DUF3290 (PF11694, IPR021707): Protein of unknown function (DUF3290) Lactamase_B_2 (PF12706, IPR001279): Beta-lactamase superfamily domain |
57 |
DDA1 | interactor | 5 | 0.600 | 0.742 | DDA1 (PF10172, IPR018276): Det1 complexing ubiquitin ligase |
58 |
DDX5 | oncoprotein | 48 | 0.247 | 248.900 | DEAD (PF00270, IPR011545): DEAD/DEAH box helicase P68HR (PF08061, IPR012587): P68HR (NUC004) repeat ResIII (PF04851, IPR006935): Type III restriction enzyme, res subunit Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain |
59 |
DHX38 | interactor | 8 | 0.607 | 3.906 | DEAD (PF00270, IPR011545): DEAD/DEAH box helicase OB_NTP_bind (PF07717, IPR011709): Oligonucleotide/oligosaccharide-binding (OB)-fold DUF1764 (PF08576, IPR013885): Eukaryotic protein of unknown function (DUF1764) HA2 (PF04408, IPR007502, SM00847): Helicase associated domain (HA2) Nucleo_P87 (PF07267, IPR009893): Nucleopolyhedrovirus capsid protein P87 Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain DUF2956 (PF11169, IPR021339): Protein of unknown function (DUF2956) |
60 |
DHX9 | oncoprotein | 57 | 0.362 | 269.954 | DEAD (PF00270, IPR011545): DEAD/DEAH box helicase dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif OB_NTP_bind (PF07717, IPR011709): Oligonucleotide/oligosaccharide-binding (OB)-fold T2SSE (PF00437, IPR001482): Type II/IV secretion system protein HA2 (PF04408, IPR007502, SM00847): Helicase associated domain (HA2) Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain |
61 |
DNAJC7 | interactor | 17 | 0.419 | 27.903 | DnaJ (PF00226, IPR001623, SM00271): DnaJ domain TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat Rapsyn_N (PF10579, IPR019568): Rapsyn N-terminal myristoylation and linker region ANAPC3 (PF12895): Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 (PF13414, IPR011990): TPR repeat TPR_17 (PF13431): Tetratricopeptide repeat |
62 |
E4F1 | interactor | 4 | 0.833 | 0.500 | FYVE (PF01363, IPR000306, SM00064): FYVE zinc finger zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_4 (PF13894): C2H2-type zinc finger zf-H2C2_5 (PF13909): C2H2-type zinc-finger domain zf-C2H2_11 (PF16622, IPR007087): zinc-finger C2H2-type |
63 |
EED | suppressor | 45 | 0.245 | 219.723 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160 ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain |
64 |
EFTUD2 | interactor | 39 | 0.312 | 133.227 | EFG_C (PF00679, IPR000640, SM00838): Elongation factor G C-terminus EFG_IV (PF03764, IPR005517, SM00889): Elongation factor G, domain IV GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2 EFG_II (PF14492, IPR009022): Elongation Factor G, domain II EFTUD2 (PF16004, IPR031950): 116 kDa U5 small nuclear ribonucleoprotein component N-terminus |
65 |
EGFR | oncoprotein | 43 | 0.238 | 320.511 | Furin-like (PF00757, IPR006211): Furin-like cysteine rich region Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase Recep_L_domain (PF01030, IPR000494): Receptor L domain GAPT (PF11770, IPR021082): GRB2-binding adapter (GAPT) GF_recep_IV (PF14843, IPR032778): Growth factor receptor domain IV |
66 |
EHD1 | interactor | 8 | 0.524 | 5.068 | Gp-FAR-1 (PF05823, IPR008632): Nematode fatty acid retinoid binding protein (Gp-FAR-1) Gtr1_RagA (PF04670, IPR006762): Gtr1/RagA G protein conserved region Dynamin_N (PF00350, IPR001401, SM00053): Dynamin family EF-hand_4 (PF12763, IPR000261): Cytoskeletal-regulatory complex EF hand EHD_N (PF16880, IPR031692): N-terminal EH-domain containing protein |
67 |
EIF2S2 | interactor | 11 | 0.527 | 3.418 | DUF1754 (PF08555, IPR013865): Eukaryotic family of unknown function (DUF1754) ETRAMP (PF09716, IPR006389): Malarial early transcribed membrane protein (ETRAMP) eIF-5_eIF-2B (PF01873, IPR002735, SM00653): Domain found in IF2B/IF5 Cytochrom_c3_2 (PF14537): Cytochrome c3 |
68 |
EIF4EBP1 | oncoprotein | 7 | 0.429 | 5.112 | eIF_4EBP (PF05456, IPR008606): Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) |
69 |
ELAVL1 | oncoprotein | 55 | 0.202 | 553.305 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
70 |
EMD | interactor | 31 | 0.248 | 156.310 | LEM (PF03020, IPR003887, SM00540): LEM domain SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein |
71 |
EP300 | oncoprotein | 50 | 0.257 | 361.290 | Creb_binding (PF09030, IPR014744): Creb binding DUF902 (PF06001, IPR010303): Domain of Unknown Function (DUF902) Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region KIX (PF02172, IPR003101): KIX domain RR_TM4-6 (PF06459, IPR009460): Ryanodine Receptor TM 4-6 TPX2 (PF06886, IPR027329): Targeting protein for Xklp2 (TPX2) zf-TAZ (PF02135, IPR000197, SM00551): TAZ zinc finger HAT_KAT11 (PF08214, IPR013178): Histone acetylation protein Bromodomain (PF00439, IPR001487, SM00297): Bromodomain ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type |
72 |
ERG | oncoprotein | 17 | 0.478 | 15.110 | Ets (PF00178, IPR000418, SM00413): Ets-domain SAM_2 (PF07647, IPR011510): SAM domain (Sterile alpha motif) SAM_PNT (PF02198, IPR003118, SM00251): Sterile alpha motif (SAM)/Pointed domain |
73 |
ESR1 | suppressor | 54 | 0.293 | 339.606 | Oest_recep (PF02159, IPR001292): Oestrogen receptor zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor ESR1_C (PF12743, IPR024736): Oestrogen-type nuclear receptor final C-terminal |
74 |
FAF2 | interactor | 15 | 0.330 | 31.244 | DUF1682 (PF07946, IPR012879): Protein of unknown function (DUF1682) UBX (PF00789, IPR001012, SM00166): UBX domain Thioredoxin_7 (PF13899): Thioredoxin-like UBA_4 (PF14555): UBA-like domain |
75 |
FBXO6 | interactor | 30 | 0.290 | 102.844 | FBA (PF04300, IPR007397): F-box associated region F-box-like (PF12937, IPR001810): F-box-like |
76 |
FLII | oncoprotein | 15 | 0.533 | 11.341 | Gelsolin (PF00626, IPR007123): Gelsolin repeat SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal U1snRNP70_N (PF12220, IPR022023): U1 small nuclear ribonucleoprotein of 70kDa MW N terminal LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies) LRR_8 (PF13855, IPR001611): Leucine rich repeat |
77 |
FN1 | oncoprotein | 41 | 0.306 | 123.211 | fn1 (PF00039, IPR000083, SM00058): Fibronectin type I domain fn2 (PF00040, IPR000562, SM00059): Fibronectin type II domain fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369) |
78 |
FOXRED2 | interactor | 3 | 1.000 | 0 | Pyr_redox_3 (PF13738): Pyridine nucleotide-disulphide oxidoreductase |
79 |
FZR1 | suppressor | 9 | 0.389 | 10.251 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain |
80 |
GBAS | interactor | 4 | 0.833 | 0.143 | NIPSNAP (PF07978, IPR012577): NIPSNAP |
81 |
GRK5 | protein found in more fusions | 13 | 0.318 | 18.377 | Pkinase (PF00069, IPR000719): Protein kinase domain RGS (PF00615, IPR000342, SM00315): Regulator of G protein signaling domain |
82 |
GSK3A | interactor | 5 | 0.800 | 0.265 | Pkinase (PF00069, IPR000719): Protein kinase domain |
83 |
GSK3B | suppressor | 18 | 0.360 | 46.026 | Pkinase (PF00069, IPR000719): Protein kinase domain |
84 |
GTF2I | interactor | 25 | 0.290 | 92.373 | GTF2I (PF02946, IPR004212): GTF2I-like repeat |
85 |
GZMB | interactor | 5 | 0.600 | 1.280 | Trypsin (PF00089, IPR001254, SM00020): Trypsin |
86 |
H2AFX | suppressor | 37 | 0.323 | 152.614 | Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4 Histone_H2A_C (PF16211, IPR032454): C-terminus of histone H2A |
87 |
H3F3A | oncoprotein | 14 | 0.505 | 13.869 | Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4 |
88 |
HDAC11 | interactor | 7 | 0.381 | 6.261 | Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain |
89 |
HDAC3 | suppressor | 26 | 0.347 | 68.729 | Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain |
90 |
HDAC5 | protein found in more fusions | 34 | 0.350 | 76.098 | Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain NOA36 (PF06524, IPR010531): NOA36 protein Activator_LAG-3 (PF11498, IPR021587): Transcriptional activator LAG-3 HDAC4_Gln (PF12203, IPR024643): Glutamine rich N terminal domain of histone deacetylase 4 |
91 |
HDGF | interactor | 24 | 0.344 | 49.631 | PWWP (PF00855, IPR000313, SM00293): PWWP domain |
92 |
HDLBP | oncoprotein | 17 | 0.456 | 18.915 | BMC (PF00936, IPR000249, SM00877): BMC domain KH_1 (PF00013, IPR004088, SM00322): KH domain KH_4 (PF13083): KH domain KH_5 (PF13184, IPR025249): NusA-like KH domain SLS (PF14611, IPR032741): Mitochondrial inner-membrane-bound regulator DUF4530 (PF15039, IPR029202): Domain of unknown function (DUF4530) |
93 |
HIST1H1A | interactor | 12 | 0.364 | 13.689 | Mucin (PF01456, IPR000458): Mucin-like glycoprotein Linker_histone (PF00538, IPR005818, SM00526): linker histone H1 and H5 family CPSF100_C (PF13299, IPR025069): Cleavage and polyadenylation factor 2 C-terminal |
94 |
HIST1H1C | oncoprotein | 18 | 0.373 | 26.489 | Amelin (PF05111, IPR007798, SM00817): Ameloblastin precursor (Amelin) Linker_histone (PF00538, IPR005818, SM00526): linker histone H1 and H5 family DUF4349 (PF14257, IPR025645): Domain of unknown function (DUF4349) |
95 |
HIST1H3A | interactor | 28 | 0.208 | 156.174 | Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4 |
96 |
HIST1H3E | interactor | 19 | 0.363 | 26.768 | Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4 |
97 |
HNRNPA1 | interactor | 63 | 0.344 | 447.025 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HnRNPA1 (PF11627, IPR021662): Nuclear factor hnRNPA1 |
98 |
HNRNPC | protein found in more fusions | 39 | 0.434 | 69.795 | APG6 (PF04111, IPR007243): Autophagy protein Apg6 RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SURF2 (PF05477, IPR008833): Surfeit locus protein 2 (SURF2) |
99 |
HOXB7 | interactor | 4 | 1.000 | 0 | Homeobox (PF00046, IPR001356, SM00389): Homeobox domain |
100 |
HSF1 | protein found in more fusions | 12 | 0.382 | 14.305 | DUF247 (PF03140, IPR004158): Plant protein of unknown function Vert_HS_TF (PF06546, IPR010542): Vertebrate heat shock transcription factor HSF_DNA-bind (PF00447, IPR000232, SM00415): HSF-type DNA-binding |
101 |
HSP90AA1 | oncoprotein | 66 | 0.202 | 809.052 | HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HSP90 (PF00183, IPR001404): Hsp90 protein |
102 |
HSP90AB1 | oncoprotein | 52 | 0.216 | 430.712 | HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HSP90 (PF00183, IPR001404): Hsp90 protein |
103 |
HSPA5 | oncoprotein | 52 | 0.307 | 327.488 | HSP70 (PF00012, IPR013126): Hsp70 protein |
104 |
HSPA8 | oncoprotein | 54 | 0.245 | 387.716 | HSP70 (PF00012, IPR013126): Hsp70 protein |
105 |
IKBKAP | interactor | 15 | 0.374 | 21.272 | IKI3 (PF04762, IPR006849): IKI3 family Clathrin (PF00637, IPR000547, SM00299): Region in Clathrin and VPS MMU163 (PF17119, IPR031342): Mitochondrial protein up-regulated during meiosis |
106 |
IKBKB | protein found in more fusions | 13 | 0.545 | 6.597 | FliT (PF05400, IPR008622): Flagellar protein FliT Glyco_hydro_65m (PF03632, IPR005195): Glycosyl hydrolase family 65 central catalytic domain Pkinase (PF00069, IPR000719): Protein kinase domain SlyX (PF04102, IPR007236): SlyX ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family IKKbetaNEMObind (PF12179, IPR022007): I-kappa-kinase-beta NEMO binding domain |
107 |
ILF2 | interactor | 43 | 0.434 | 96.545 | DZF (PF07528, IPR006561, SM00572): DZF domain |
108 |
ILF3 | oncoprotein | 46 | 0.325 | 208.651 | dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif DZF (PF07528, IPR006561, SM00572): DZF domain |
109 |
ILK | suppressor | 19 | 0.392 | 30.171 | Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_4 (PF13637): Ankyrin repeats (many copies) Ank_5 (PF13857): Ankyrin repeats (many copies) |
110 |
IQCB1 | interactor | 8 | 0.393 | 2.181 | DUF1765 (PF08578, IPR013887): Protein of unknown function (DUF1765) IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif HJURP_C (PF12347, IPR022102): Holliday junction regulator protein family C-terminal repeat Condensin2nSMC (PF12422, IPR024741): Condensin II non structural maintenance of chromosomes subunit |
111 |
ITGA4 | interactor | 31 | 0.359 | 70.038 | FG-GAP (PF01839, IPR013517): FG-GAP repeat Integrin_alpha (PF00357, IPR018184): Integrin alpha cytoplasmic region Integrin_alpha2 (PF08441, IPR013649): Integrin alpha |
112 |
JUN | oncoprotein | 27 | 0.378 | 65.146 | bZIP_1 (PF00170, IPR004827): bZIP transcription factor Jun (PF03957, IPR005643): Jun-like transcription factor |
113 |
KAT2A | interactor | 12 | 0.600 | 4.123 | Acetyltransf_1 (PF00583, IPR000182): Acetyltransferase (GNAT) family PCAF_N (PF06466, IPR009464): PCAF (P300/CBP-associated factor) N-terminal domain Bromodomain (PF00439, IPR001487, SM00297): Bromodomain NICE-1 (PF15845, IPR031698): Cysteine-rich C-terminal 1 family |
114 |
KAT5 | suppressor | 27 | 0.375 | 57.901 | MOZ_SAS (PF01853, IPR002717): MOZ/SAS family Tudor-knot (PF11717, IPR025995): RNA binding activity-knot of a chromodomain |
115 |
KAT8 | protein found in more fusions | 9 | 0.500 | 6.949 | MOZ_SAS (PF01853, IPR002717): MOZ/SAS family Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain) Tudor-knot (PF11717, IPR025995): RNA binding activity-knot of a chromodomain |
116 |
LGR4 | interactor | 10 | 0.389 | 6.150 | 7tm_1 (PF00001, IPR000276): 7 transmembrane receptor (rhodopsin family) LRR_1 (PF00560, IPR001611): Leucine Rich Repeat LRRNT (PF01462, IPR000372, SM00013): Leucine rich repeat N-terminal domain LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies) LRR_8 (PF13855, IPR001611): Leucine rich repeat |
117 |
LIG4 | interactor | 7 | 0.714 | 1.580 | APG17 (PF04108, IPR007240): Autophagy protein Apg17 BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain DNA_ligase_A_C (PF04679, IPR012309): ATP dependent DNA ligase C terminal region DNA_ligase_A_M (PF01068, IPR012310): ATP dependent DNA ligase domain DNA_ligase_A_N (PF04675, IPR012308): DNA ligase N terminus DNA_ligase_IV (PF11411, IPR021536): DNA ligase IV RTT107_BRCT_5 (PF16770, IPR001357): Regulator of Ty1 transposition protein 107 BRCT domain |
118 |
LMNA | protein found in more fusions | 40 | 0.341 | 154.977 | Filament (PF00038, IPR001664): Intermediate filament protein LTD (PF00932, IPR001322): Lamin Tail Domain Uso1_p115_C (PF04871, IPR006955): Uso1 / p115 like vesicle tethering protein, C terminal region DUF3450 (PF11932, IPR016866): Protein of unknown function (DUF3450) DUF4407 (PF14362, IPR025519): Domain of unknown function (DUF4407) |
119 |
LRRFIP1 | oncoprotein | 10 | 0.667 | 5.544 | CENP-H (PF05837, IPR008426): Centromere protein H (CENP-H) Rxt3 (PF08642, IPR013951): Histone deacetylation protein Rxt3 LRRFIP (PF09738, IPR019139): LRRFIP family RP-C_C (PF11800, IPR021760): Replication protein C C-terminal region Coilin_N (PF15862, IPR031722): Coilin N-terminus |
120 |
LRRK2 | oncoprotein | 13 | 0.318 | 24.989 | Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat ATP-synt_ab (PF00006, IPR000194): ATP synthase alpha/beta family, nucleotide-binding domain DUF1043 (PF06295, IPR009386): Protein of unknown function (DUF1043) T2SSE (PF00437, IPR001482): Type II/IV secretion system protein Roc (PF08477, IPR013684): Ras of Complex, Roc, domain of DAPkinase Pkinase (PF00069, IPR000719): Protein kinase domain Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies) PQQ_2 (PF13360, IPR002372): PQQ-like domain LRR_8 (PF13855, IPR001611): Leucine rich repeat COR (PF16095, IPR032171): C-terminal of Roc, COR, domain |
121 |
LYN | oncoprotein | 11 | 0.600 | 2.996 | Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain |
122 |
MAPK8 | oncoprotein | 16 | 0.400 | 27.389 | DUF530 (PF04409, IPR007503): Protein of unknown function (DUF530) Pkinase (PF00069, IPR000719): Protein kinase domain |
123 |
MAPK9 | suppressor | 9 | 0.500 | 7.860 | Pkinase (PF00069, IPR000719): Protein kinase domain Kinase-like (PF14531, IPR027916): Kinase-like |
124 |
MBP | interactor | 3 | 0.667 | 0.400 | Myelin_MBP (PF01669, IPR000548): Myelin basic protein |
125 |
MCM2 | oncoprotein | 56 | 0.294 | 383.409 | AAA_3 (PF07726, IPR011703): ATPase family associated with various cellular activities (AAA) MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family MCM2_N (PF12619, IPR008045): Mini-chromosome maintenance protein 2 MCM_N (PF14551, IPR027925): MCM N-terminal domain MCM_OB (PF17207): MCM OB domain |
126 |
MDC1 | suppressor | 36 | 0.313 | 172.710 | FHA (PF00498, IPR000253, SM00240): FHA domain DUF3274 (PF11678, IPR021692): Protein of unknown function (DUF3274) Yop-YscD_cpl (PF16697, IPR032030): Inner membrane component of T3SS, cytoplasmic domain RTT107_BRCT_5 (PF16770, IPR001357): Regulator of Ty1 transposition protein 107 BRCT domain |
127 |
METTL1 | interactor | 6 | 0.533 | 4.100 | Methyltransf_4 (PF02390, IPR003358): Putative methyltransferase |
128 |
MEX3C | interactor | 6 | 0.533 | 0.857 | KH_1 (PF00013, IPR004088, SM00322): KH domain zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger) |
129 |
MGMT | interactor | 13 | 0.577 | 5.355 | DNA_binding_1 (PF01035, IPR014048): 6-O-methylguanine DNA methyltransferase, DNA binding domain Methyltransf_1N (PF02870, IPR008332): 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain |
130 |
MKNK1 | interactor | 3 | 1.000 | 0 | Pkinase (PF00069, IPR000719): Protein kinase domain |
131 |
MLH1 | suppressor | 14 | 0.505 | 15.722 | DNA_mis_repair (PF01119, IPR013507): DNA mismatch repair protein, C-terminal domain HATPase_c_3 (PF13589): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Mlh1_C (PF16413, IPR032189): DNA mismatch repair protein Mlh1 C-terminus |
132 |
MRE11A | oncoprotein | 41 | 0.315 | 216.929 | APG6 (PF04111, IPR007243): Autophagy protein Apg6 Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase Mre11_DNA_bind (PF04152, IPR007281): Mre11 DNA-binding presumed domain |
133 |
MSH6 | oncoprotein | 31 | 0.325 | 122.124 | MutS_I (PF01624, IPR007695): MutS domain I MutS_II (PF05188, IPR007860): MutS domain II PWWP (PF00855, IPR000313, SM00293): PWWP domain MutS_V (PF00488, IPR000432, SM00534): MutS domain V MutS_III (PF05192, IPR007696, SM00533): MutS domain III UPF0524 (PF15823, IPR029670): UPF0524 of C3orf70 |
134 |
MSL3 | interactor | 3 | 1.000 | 0 | GET2 (PF08690, IPR028143): GET complex subunit GET2 MRG (PF05712, IPR026541): MRG Tudor-knot (PF11717, IPR025995): RNA binding activity-knot of a chromodomain |
135 |
MYC | oncoprotein | 47 | 0.276 | 296.763 | HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain Myc-LZ (PF02344, IPR003327): Myc leucine zipper domain Myc_N (PF01056, IPR012682): Myc amino-terminal region |
136 |
NBN | suppressor | 29 | 0.352 | 97.394 | FHA (PF00498, IPR000253, SM00240): FHA domain Nbs1_C (PF08599, IPR013908): DNA damage repair protein Nbs1 NIBRIN_BRCT_II (PF16508, IPR032429): Second BRCT domain on Nijmegen syndrome breakage protein RTT107_BRCT_5 (PF16770, IPR001357): Regulator of Ty1 transposition protein 107 BRCT domain |
137 |
NCF1 | interactor | 6 | 0.500 | 4.500 | p47_phox_C (PF08944, IPR015039): NADPH oxidase subunit p47Phox, C terminal domain PX (PF00787, IPR001683, SM00312): PX domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain NECFESHC (PF16621, IPR032136): SH3 terminal domain of 2nd SH3 on Neutrophil cytosol factor 1 |
138 |
NCF2 | interactor | 3 | 1.000 | 0 | PB1 (PF00564, IPR000270, SM00666): PB1 domain TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat SH3_1 (PF00018, IPR001452, SM00326): SH3 domain TPR_16 (PF13432): Tetratricopeptide repeat |
139 |
NCF4 | interactor | 4 | 0.667 | 2.000 | PX (PF00787, IPR001683, SM00312): PX domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain |
140 |
NCOA6 | oncoprotein | 16 | 0.495 | 18.916 | DUF719 (PF05334, IPR007998): Protein of unknown function (DUF719) Fes1 (PF08609, IPR013918): Nucleotide exchange factor Fes1 Presenilin (PF01080, IPR001108): Presenilin DUF3729 (PF12526, IPR022202): Protein of unknown function (DUF3729) Nucleic_acid_bd (PF13820, IPR032715): Putative nucleic acid-binding region NST1 (PF13945, IPR025279): Salt tolerance down-regulator |
141 |
NOS2 | interactor | 13 | 0.424 | 8.012 | FAD_binding_1 (PF00667, IPR003097): FAD binding domain Flavodoxin_1 (PF00258, IPR008254): Flavodoxin NAD_binding_1 (PF00175, IPR001433): Oxidoreductase NAD-binding domain NO_synthase (PF02898, IPR004030): Nitric oxide synthase, oxygenase domain |
142 |
NOTCH1 | suppressor | 18 | 0.279 | 35.238 | Ank (PF00023, IPR002110, SM00248): Ankyrin repeat EGF (PF00008, IPR000742, SM00181): EGF-like domain EGF_2 (PF07974, IPR013111): EGF-like domain EGF_alliinase (PF04863, IPR006947): Alliinase EGF-like domain EGF_CA (PF07645, IPR001881, SM00179): Calcium-binding EGF domain NOD (PF06816, IPR010660): NOTCH protein NODP (PF07684, IPR011656): NOTCH protein TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit Notch (PF00066, IPR000800, SM00004): LNR domain DUF3454 (PF11936, IPR024600): Domain of unknown function (DUF3454) hEGF (PF12661, IPR013032): Human growth factor-like EGF cEGF (PF12662, IPR026823): Complement Clr-like EGF-like Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) |
143 |
NR1H4 | interactor | 7 | 0.810 | 0.939 | LRV_FeS (PF05484, IPR008665): LRV protein FeS4 cluster zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor |
144 |
NR3C1 | protein found in more fusions | 15 | 0.451 | 12.892 | GCR (PF02155, IPR001409): Glucocorticoid receptor zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor |
145 |
NTRK1 | oncoprotein | 87 | 0.184 | 1423.850 | I-set (PF07679, IPR013098): Immunoglobulin I-set domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase LRR_8 (PF13855, IPR001611): Leucine rich repeat TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain |
146 |
NUCB1 | interactor | 6 | 0.600 | 2.630 | DUF1104 (PF06518, IPR009488): Protein of unknown function (DUF1104) Spc24 (PF08286, IPR013252): Spc24 subunit of Ndc80 DUF2967 (PF11179, IPR021349): Protein of unknown function (DUF2967) DUF3552 (PF12072, IPR022711): Domain of unknown function (DUF3552) EF-hand_7 (PF13499, IPR011992): EF-hand domain pair |
147 |
NUP107 | interactor | 14 | 0.538 | 9.910 | Nup84_Nup100 (PF04121, IPR007252): Nuclear pore protein 84 / 107 |
148 |
NUP35 | interactor | 8 | 0.679 | 1.821 | Nup35_RRM (PF05172, IPR007846): Nup53/35/40-type RNA recognition motif |
149 |
NUP85 | interactor | 12 | 0.439 | 14.955 | Nucleopor_Nup85 (PF07575, IPR011502): Nup85 Nucleoporin |
150 |
OBSL1 | interactor | 48 | 0.314 | 196.393 | BiPBP_C (PF06832, IPR009647): Penicillin-Binding Protein C-terminus Family fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain Herpes_gE (PF02480, IPR003404): Alphaherpesvirus glycoprotein E I-set (PF07679, IPR013098): Immunoglobulin I-set domain V-set (PF07686, IPR013106): Immunoglobulin V-set domain Ig_3 (PF13927): Immunoglobulin domain Ig_4 (PF16680, IPR032052): T-cell surface glycoprotein CD3 delta chain Izumo-Ig (PF16706, IPR032699): Izumo-like Immunoglobulin domain |
151 |
PAN2 | interactor | 24 | 0.315 | 50.502 | RNase_T (PF00929, IPR013520): Exonuclease UCH_1 (PF13423, IPR001394): Ubiquitin carboxyl-terminal hydrolase WD40_like (PF17005, IPR031544): WD40-like domain |
152 |
PARP1 | suppressor | 60 | 0.214 | 552.284 | BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain PADR1 (PF08063, IPR012982): PADR1 (NUC008) domain PARP (PF00644, IPR012317): Poly(ADP-ribose) polymerase catalytic domain PARP_reg (PF02877, IPR004102): Poly(ADP-ribose) polymerase, regulatory domain WGR (PF05406, IPR008893, SM00773): WGR domain zf-PARP (PF00645, IPR001510): Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region |
153 |
PCNA | oncoprotein | 45 | 0.254 | 285.757 | PCNA_C (PF02747, IPR022649): Proliferating cell nuclear antigen, C-terminal domain PCNA_N (PF00705, IPR022648): Proliferating cell nuclear antigen, N-terminal domain |
154 |
PDX1 | suppressor | 3 | 1.000 | 0 | CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal Homeobox (PF00046, IPR001356, SM00389): Homeobox domain TMEM171 (PF15471, IPR029173): Transmembrane protein family 171 |
155 |
PGR | suppressor | 14 | 0.679 | 5.442 | Prog_receptor (PF02161, IPR000128): Progesterone receptor zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor |
156 |
PHGDH | interactor | 23 | 0.356 | 40.353 | 2-Hacid_dh_C (PF02826, IPR006140): D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain |
157 |
PHKG2 | interactor | 3 | 1.000 | 0 | APH (PF01636, IPR002575): Phosphotransferase enzyme family Pkinase (PF00069, IPR000719): Protein kinase domain |
158 |
PIDD1 | interactor | 5 | 0.400 | 2.344 | Death (PF00531, IPR000488, SM00005): Death domain ZU5 (PF00791, IPR000906, SM00218): ZU5 domain Peptidase_S68 (PF10461, IPR019502): Peptidase S68 LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies) LRR_8 (PF13855, IPR001611): Leucine rich repeat |
159 |
PINK1 | protein found in more fusions | 5 | 1.000 | 0 | Pkinase (PF00069, IPR000719): Protein kinase domain |
160 |
PMS2 | oncoprotein | 9 | 0.528 | 3.813 | DNA_mis_repair (PF01119, IPR013507): DNA mismatch repair protein, C-terminal domain MORN_2 (PF07661, IPR011652): MORN repeat variant MutL_C (PF08676, IPR014790, SM00853): MutL C terminal dimerisation domain HATPase_c_3 (PF13589): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase |
161 |
PNKP | interactor | 13 | 0.513 | 12.852 | PNK3P (PF08645, IPR013954): Polynucleotide kinase 3 phosphatase AAA_33 (PF13671): AAA domain |
162 |
POT1 | interactor | 9 | 0.643 | 3.896 | POT1 (PF02765, IPR011564, SM00976): Telomeric single stranded DNA binding POT1/CDC13 tRNA_anti-codon (PF01336, IPR004365): OB-fold nucleic acid binding domain POT1PC (PF16686, IPR032042): ssDNA-binding domain of telomere protection protein |
163 |
POU2F1 | protein found in more fusions | 14 | 0.615 | 6.845 | Pou (PF00157, IPR000327, SM00352): Pou domain - N-terminal to homeobox domain Homeobox (PF00046, IPR001356, SM00389): Homeobox domain DUF3597 (PF12200, IPR022016): Domain of unknown function (DUF3597) |
164 |
POU5F1 | oncoprotein | 18 | 0.279 | 45.414 | Pou (PF00157, IPR000327, SM00352): Pou domain - N-terminal to homeobox domain Homeobox (PF00046, IPR001356, SM00389): Homeobox domain |
165 |
PPP2CA | suppressor | 28 | 0.235 | 110.962 | Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase STPPase_N (PF16891, IPR031675): Serine-threonine protein phosphatase N-terminal domain |
166 |
PPP6C | interactor | 14 | 0.330 | 32.005 | Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase |
167 |
PPP6R1 | interactor | 11 | 0.473 | 15.954 | CENP-B_dimeris (PF09026, IPR015115): Centromere protein B dimerisation domain SAPS (PF04499, IPR007587): SIT4 phosphatase-associated protein WRNPLPNID (PF15017): Putative WW-binding domain and destruction box |
168 |
PPP6R2 | interactor | 7 | 0.619 | 4.600 | SAMP (PF05924, IPR009224): SAMP Motif SAPS (PF04499, IPR007587): SIT4 phosphatase-associated protein |
169 |
PPP6R3 | interactor | 15 | 0.343 | 36.322 | SAPS (PF04499, IPR007587): SIT4 phosphatase-associated protein |
170 |
PRDX1 | oncoprotein | 32 | 0.258 | 127.441 | AhpC-TSA (PF00578, IPR000866): AhpC/TSA family 1-cysPrx_C (PF10417, IPR019479): C-terminal domain of 1-Cys peroxiredoxin |
171 |
PRKAB2 | interactor | 3 | 1.000 | 0 | AMPKBI (PF04739, IPR006828, SM01010): 5'-AMP-activated protein kinase beta subunit, interaction domain AMPK1_CBM (PF16561, IPR032640): Glycogen recognition site of AMP-activated protein kinase |
172 |
PRPF8 | oncoprotein | 36 | 0.336 | 98.443 | PRO8NT (PF08082, IPR012591): PRO8NT (NUC069), PrP8 N-terminal domain PROCN (PF08083, IPR012592): PROCN (NUC071) domain PROCT (PF08084, IPR012984): PROCT (NUC072) domain RRM_4 (PF10598, IPR019582): RNA recognition motif of the spliceosomal PrP8 U5_2-snRNA_bdg (PF10597, IPR019581): U5-snRNA binding site 2 of PrP8 U6-snRNA_bdg (PF10596, IPR019580): U6-snRNA interacting domain of PrP8 JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease PRP8_domainIV (PF12134, IPR021983): PRP8 domain IV core |
173 |
PTER | interactor | 3 | 1.000 | 0 | PTE (PF02126, IPR001559): Phosphotriesterase family |
174 |
RAD17 | interactor | 4 | 0.667 | 0.686 | Mvb12 (PF09452, IPR019014): ESCRT-I subunit Mvb12 Rad17 (PF03215): Rad17 cell cycle checkpoint protein |
175 |
RAD21 | oncoprotein | 23 | 0.372 | 36.209 | Rad21_Rec8 (PF04824, IPR006909): Conserved region of Rad21 / Rec8 like protein Rad21_Rec8_N (PF04825, IPR006910): N terminus of Rad21 / Rec8 like protein FAM176 (PF14851): FAM176 family WRNPLPNID (PF15017): Putative WW-binding domain and destruction box |
176 |
RANBP2 | oncoprotein | 29 | 0.349 | 97.214 | Pro_isomerase (PF00160, IPR002130): Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat Ran_BP1 (PF00638, IPR000156, SM00160): RanBP1 domain zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others DUF2693 (PF10902, IPR024401): Protein of unknown function (DUF2693) IR1-M (PF12185, IPR022011): Nup358/RanBP2 E3 ligase domain Dmrt1 (PF12374, IPR022114): Double-sex mab3 related transcription factor 1 TPR_9 (PF13371, IPR011990): Tetratricopeptide repeat TPR_11 (PF13414, IPR011990): TPR repeat TPR_12 (PF13424): Tetratricopeptide repeat TPR_19 (PF14559): Tetratricopeptide repeat |
177 |
RASSF1 | suppressor | 5 | 0.667 | 1.000 | RA (PF00788, IPR000159, SM00314): Ras association (RalGDS/AF-6) domain C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain) Nore1-SARAH (PF16517, IPR011524): Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain |
178 |
RBBP8 | suppressor | 8 | 0.619 | 2.970 | ZapB (PF06005, IPR009252): Cell division protein ZapB Exonuc_VII_L (PF02601, IPR020579): Exonuclease VII, large subunit SAE2 (PF08573, IPR013882): DNA repair protein endonuclease SAE2/CtIP C-terminus CtIP_N (PF10482, IPR019518): Tumour-suppressor protein CtIP N-terminal domain DUF4446 (PF14584, IPR027981): Protein of unknown function (DUF4446) |
179 |
RBM25 | interactor | 16 | 0.300 | 17.898 | Vfa1 (PF08432, IPR013640): AAA-ATPase Vps4-associated protein 1 PWI (PF01480, IPR002483, SM00311): PWI domain RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SMN (PF06003, IPR010304): Survival motor neuron protein (SMN) SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal MIP-T3 (PF10243): Microtubule-binding protein MIP-T3 DUF3441 (PF11923, IPR021846): Domain of unknown function (DUF3441) U1snRNP70_N (PF12220, IPR022023): U1 small nuclear ribonucleoprotein of 70kDa MW N terminal DUF4778 (PF16008, IPR031958): Domain of unknown function (DUF4778) |
180 |
RECQL5 | oncoprotein | 9 | 0.556 | 3.927 | DEAD (PF00270, IPR011545): DEAD/DEAH box helicase RecQ5 (PF06959, IPR010716): RecQ helicase protein-like 5 (RecQ5) SRI (PF08236, IPR013257): SRI (Set2 Rpb1 interacting) domain TFIIS_M (PF07500, IPR003618): Transcription factor S-II (TFIIS), central domain Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain RecQ_Zn_bind (PF16124, IPR032284): RecQ zinc-binding TAtT (PF16811, IPR031823): TRAP transporter T-component |
181 |
RELA | oncoprotein | 34 | 0.318 | 143.428 | DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region RHD_DNA_bind (PF00554, IPR011539): Rel homology DNA-binding domain RHD_dimer (PF16179, IPR032397): Rel homology dimerisation domain |
182 |
RFC2 | interactor | 21 | 0.367 | 48.976 | AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA) Rep_fac_C (PF08542, IPR013748): Replication factor C C-terminal domain AAA_16 (PF13191): AAA ATPase domain AAA_assoc_2 (PF16193, IPR032423): AAA C-terminal domain |
183 |
RNF144A | suppressor | 2 | 0 | 0 | IBR (PF01485, IPR002867, SM00647): IBR domain, a half RING-finger domain zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain |
184 |
RPA1 | suppressor | 59 | 0.301 | 413.530 | Rep-A_N (PF04057, IPR007199): Replication factor-A protein 1, N-terminal domain Rep_fac-A_C (PF08646, IPR013955): Replication factor-A C terminal domain tRNA_anti-codon (PF01336, IPR004365): OB-fold nucleic acid binding domain REPA_OB_2 (PF16900, IPR031657): Replication protein A OB domain |
185 |
RPA2 | oncoprotein | 44 | 0.331 | 161.395 | RPA_C (PF08784, IPR014892): Replication protein A C terminal tRNA_anti-codon (PF01336, IPR004365): OB-fold nucleic acid binding domain RMI2 (PF16100, IPR032245): RecQ-mediated genome instability protein 2 |
186 |
RPA3 | interactor | 40 | 0.335 | 111.287 | Rep_fac-A_3 (PF08661, IPR013970): Replication factor A protein 3 |
187 |
RPS11 | interactor | 17 | 0.397 | 12.675 | Ribosomal_S17 (PF00366, IPR000266): Ribosomal protein S17 Ribosomal_S17_N (PF16205, IPR032440): Ribosomal_S17 N-terminal |
188 |
RTCB | interactor | 24 | 0.460 | 41.736 | RtcB (PF01139, IPR001233): tRNA-splicing ligase RtcB |
189 |
RUVBL1 | oncoprotein | 41 | 0.227 | 248.744 | TIP49 (PF06068, IPR010339): TIP49 C-terminus |
190 |
RYK | oncoprotein | 6 | 0.667 | 3.143 | Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase WIF (PF02019, IPR003306, SM00469): WIF domain |
191 |
SAP25 | interactor | 2 | 1.000 | 0 | SAP25 (PF15476, IPR029163): Histone deacetylase complex subunit SAP25 |
192 |
SCARNA22 | interactor | 16 | 0.475 | 8.302 | NA |
193 |
SF3B6 | interactor | 18 | 0.536 | 20.032 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
194 |
SHC1 | oncoprotein | 18 | 0.500 | 16.605 | PID (PF00640, IPR006020, SM00462): Phosphotyrosine interaction domain (PTB/PID) SH2 (PF00017, IPR000980, SM00252): SH2 domain |
195 |
SIRT6 | suppressor | 13 | 0.295 | 10.734 | SIR2 (PF02146, IPR003000): Sir2 family TPP_enzyme_M (PF00205, IPR012000): Thiamine pyrophosphate enzyme, central domain |
196 |
SIRT7 | interactor | 34 | 0.275 | 134.701 | DUF563 (PF04577, IPR007657): Protein of unknown function (DUF563) SIR2 (PF02146, IPR003000): Sir2 family |
197 |
SKI | oncoprotein | 16 | 0.448 | 14.782 | c-SKI_SMAD_bind (PF08782, IPR014890, SM01046): c-SKI Smad4 binding domain Ski_Sno (PF02437, IPR003380): SKI/SNO/DAC family SlyX (PF04102, IPR007236): SlyX HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1 |
198 |
SMARCA5 | interactor | 30 | 0.352 | 62.117 | HAND (PF09110, IPR015194): HAND SLIDE (PF09111, IPR015195): SLIDE SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain DUF4200 (PF13863, IPR025252): Domain of unknown function (DUF4200) DBINO (PF13892, IPR020838): DNA-binding domain RCDG1 (PF15725, IPR031457): Renal cancer differentiation gene 1 protein |
199 |
SMARCAD1 | interactor | 19 | 0.485 | 19.145 | CUE (PF02845, IPR003892, SM00546): CUE domain Pox_D5 (PF03288, IPR004968): Poxvirus D5 protein-like SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain |
200 |
SNRPA | interactor | 13 | 0.530 | 2.539 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
201 |
SNW1 | protein found in more fusions | 55 | 0.275 | 404.241 | SKIP_SNW (PF02731, IPR004015): SKIP/SNW domain PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term SIR4_SID (PF16991, IPR031556): Sir4 SID domain |
202 |
SP1 | protein found in more fusions | 22 | 0.505 | 35.352 | zf-Di19 (PF05605, IPR008598): Drought induced 19 protein (Di19), zinc-binding Herpes_capsid (PF06112, IPR009299): Gammaherpesvirus capsid protein zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type Miga (PF10265, IPR019392): Mitoguardin zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 |
203 |
SRF | interactor | 10 | 0.528 | 4.170 | SRF-TF (PF00319, IPR002100, SM00432): SRF-type transcription factor (DNA-binding and dimerisation domain) |
204 |
SRP14 | interactor | 12 | 0.394 | 10.455 | SRP14 (PF02290, IPR003210): Signal recognition particle 14kD protein |
205 |
SRP54 | interactor | 8 | 0.571 | 3.838 | 5_3_exonuc (PF01367, IPR020045, SM00475): 5'-3' exonuclease, C-terminal SAM fold ResIII (PF04851, IPR006935): Type III restriction enzyme, res subunit SRP54 (PF00448, IPR000897, SM00962): SRP54-type protein, GTPase domain SRP54_N (PF02881, IPR013822, SM00963): SRP54-type protein, helical bundle domain SRP_SPB (PF02978, IPR004125): Signal peptide binding domain YlbD_coat (PF14071, IPR025953): Putative coat protein |
206 |
SRSF10 | interactor | 12 | 0.515 | 8.445 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term |
207 |
STAU1 | protein found in more fusions | 31 | 0.409 | 76.759 | dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif Staufen_C (PF16482, IPR032478): Staufen C-terminal domain |
208 |
SUMO2 | interactor | 19 | 0.373 | 25.469 | Rad60-SLD (PF11976, IPR022617): Ubiquitin-2 like Rad60 SUMO-like |
209 |
TELO2 | interactor | 9 | 0.472 | 11.116 | Telomere_reg-2 (PF10193, IPR019337): Telomere length regulation protein HEAT_2 (PF13646): HEAT repeats |
210 |
TERF1 | interactor | 20 | 0.339 | 51.445 | TRF (PF08558, IPR013867): Telomere repeat binding factor (TRF) Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain |
211 |
THOC6 | interactor | 10 | 0.578 | 5.790 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 (PF16529, IPR032401): WD40 region of Ge1, enhancer of mRNA-decapping protein |
212 |
THRA | suppressor | 13 | 0.485 | 13.344 | C1_2 (PF03107, IPR004146): C1 domain zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor |
213 |
THRB | suppressor | 10 | 0.556 | 6.335 | zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor |
214 |
THYN1 | interactor | 2 | 1.000 | 0 | EVE (PF01878, IPR002740): EVE domain |
215 |
TINF2 | interactor | 12 | 0.436 | 15.994 | TINF2_N (PF14973, IPR029400): TERF1-interacting nuclear factor 2 N-terminus |
216 |
TP53 | suppressor | 71 | 0.222 | 852.877 | DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region P53 (PF00870, IPR011615): P53 DNA-binding domain P53_tetramer (PF07710, IPR010991): P53 tetramerisation motif |
217 |
TPR | oncoprotein | 24 | 0.373 | 58.643 | Baculo_PEP_C (PF04513, IPR007601): Baculovirus polyhedron envelope protein, PEP, C terminus ZapB (PF06005, IPR009252): Cell division protein ZapB Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family IncA (PF04156, IPR007285): IncA protein Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein Seryl_tRNA_N (PF02403, IPR015866): Seryl-tRNA synthetase N-terminal domain TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein Jnk-SapK_ap_N (PF09744, IPR019143): JNK_SAPK-associated protein-1 XhlA (PF10779, IPR019715): Haemolysin XhlA ADIP (PF11559, IPR021622): Afadin- and alpha -actinin-Binding Alanine_zipper (PF11839, IPR021793): Alanine-zipper, major outer membrane lipoprotein DUF3373 (PF11853, IPR021803): Protein of unknown function (DUF3373) DUF4107 (PF13389, IPR025180): Protein of unknown function (DUF4107) JIP_LZII (PF16471, IPR032486): JNK-interacting protein leucine zipper II CREPT (PF16566, IPR032337): Cell-cycle alteration and expression-elevated protein in tumour DUF5082 (PF16888, IPR031681): Domain of unknown function (DUF5082) |
218 |
TRA2B | interactor | 16 | 0.525 | 18.648 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Transformer (PF06495, IPR010519): Fruit fly transformer protein |
219 |
TTI1 | interactor | 9 | 0.528 | 6.719 | Dopey_N (PF04118, IPR007249): Dopey, N-terminal HEAT (PF02985, IPR000357): HEAT repeat VHS (PF00790, IPR002014, SM00288): VHS domain CLASP_N (PF12348, IPR024395): CLASP N terminal |
220 |
TTI2 | interactor | 7 | 0.619 | 2.132 | Tti2 (PF10521, IPR018870): Tti2 family |
221 |
U2AF2 | protein found in more fusions | 43 | 0.413 | 128.675 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Transformer (PF06495, IPR010519): Fruit fly transformer protein |
222 |
UBAC2 | interactor | 4 | 0.667 | 1.333 | Rhomboid (PF01694, IPR022764): Rhomboid family UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain |
223 |
UBE2I | interactor | 38 | 0.272 | 203.640 | UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme |
224 |
UBXN6 | interactor | 6 | 0.533 | 3.800 | PUB (PF09409, IPR018997): PUB domain UBX (PF00789, IPR001012, SM00166): UBX domain |
225 |
USF1 | oncoprotein | 10 | 0.472 | 5.270 | HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain Rootletin (PF15035): Ciliary rootlet component, centrosome cohesion |
226 |
VCAM1 | interactor | 25 | 0.373 | 28.869 | C2-set (PF05790, IPR008424): Immunoglobulin C2-set domain I-set (PF07679, IPR013098): Immunoglobulin I-set domain ig (PF00047, IPR013151, SM00409): Immunoglobulin domain V-set (PF07686, IPR013106): Immunoglobulin V-set domain Ig_3 (PF13927): Immunoglobulin domain |
227 |
WRN | oncoprotein | 22 | 0.519 | 31.937 | DNA_pol_A_exo1 (PF01612, IPR002562, SM00474): 3'-5' exonuclease DEAD (PF00270, IPR011545): DEAD/DEAH box helicase HRDC (PF00570, IPR002121, SM00341): HRDC domain Laminin_II (PF06009, IPR010307): Laminin Domain II RQC (PF09382, IPR018982, SM00956): RQC domain Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain HTH_40 (PF14493, IPR029491): Helix-turn-helix domain RecQ_Zn_bind (PF16124, IPR032284): RecQ zinc-binding |
228 |
XPA | oncoprotein | 5 | 0.700 | 0.372 | XPA_C (PF05181, IPR022656): XPA protein C-terminus XPA_N (PF01286, IPR022652): XPA protein N-terminal MscS_TM (PF12794, IPR025692): Mechanosensitive ion channel inner membrane domain 1 zinc_ribbon_2 (PF13240, IPR026870): zinc-ribbon domain |
229 |
XRCC4 | interactor | 12 | 0.400 | 17.376 | XRCC4 (PF06632, IPR010585): DNA double-strand break repair and V(D)J recombination protein XRCC4 |
230 |
XRCC5 | suppressor | 76 | 0.189 | 991.591 | Ku (PF02735, IPR006164, SM00559): Ku70/Ku80 beta-barrel domain Ku_C (PF03730, IPR005160): Ku70/Ku80 C-terminal arm Ku_N (PF03731, IPR005161): Ku70/Ku80 N-terminal alpha/beta domain Ku_PK_bind (PF08785, IPR014893): Ku C terminal domain like |
231 |
XRCC6 | oncoprotein | 80 | 0.204 | 1095.534 | Ku (PF02735, IPR006164, SM00559): Ku70/Ku80 beta-barrel domain Ku_C (PF03730, IPR005160): Ku70/Ku80 C-terminal arm Ku_N (PF03731, IPR005161): Ku70/Ku80 N-terminal alpha/beta domain SAP (PF02037, IPR003034, SM00513): SAP domain |
232 |
YBX1 | oncoprotein | 31 | 0.312 | 88.234 | CSD (PF00313, IPR002059): 'Cold-shock' DNA-binding domain PBP1_TM (PF14812, IPR032730): Transmembrane domain of transglycosylase PBP1 at N-terminal FXR_C1 (PF16096, IPR032172): Fragile X-related 1 protein C-terminal region 2 |
233 |
YWHAQ | interactor | 38 | 0.279 | 176.330 | 14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein |
234 |
YY1 | protein found in more fusions | 20 | 0.439 | 22.630 | zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_4 (PF13894): C2H2-type zinc finger Keratin_2_tail (PF16210, IPR032449): Keratin type II cytoskeletal 1 tail |