1 |
PRDX1 | parental protein | 123 | 0.094 | 8908.610 | AhpC-TSA (PF00578, IPR000866): AhpC/TSA family 1-cysPrx_C (PF10417, IPR019479): C-terminal domain of 1-Cys peroxiredoxin |
2 |
ABL1 | oncoprotein | 13 | 0.470 | 17.668 | Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain F_actin_bind (PF08919, IPR015015, SM00808): F-actin binding SH3_1 (PF00018, IPR001452, SM00326): SH3 domain FRG2 (PF15315, IPR026245): Facioscapulohumeral muscular dystrophy candidate 2 |
3 |
ACAA2 | interactor | 6 | 0.733 | 1.619 | Thiolase_C (PF02803, IPR020617): Thiolase, C-terminal domain Thiolase_N (PF00108, IPR020616): Thiolase, N-terminal domain |
4 |
ADH5 | interactor | 2 | 0 | 0 | ADH_N (PF08240, IPR013154): Alcohol dehydrogenase GroES-like domain ADH_zinc_N (PF00107, IPR013149): Zinc-binding dehydrogenase ADH_zinc_N_2 (PF13602): Zinc-binding dehydrogenase |
5 |
AGO4 | interactor | 1 | 0 | 0 | ArgoL1 (PF08699, IPR014811, SM01163): Argonaute linker 1 domain PAZ (PF02170, IPR003100, SM00949): PAZ domain Piwi (PF02171, IPR003165, SM00950): Piwi domain ArgoN (PF16486, IPR032474): N-terminal domain of argonaute ArgoMid (PF16487, IPR032473): Mid domain of argonaute ArgoL2 (PF16488, IPR032472): Argonaute linker 2 domain |
6 |
ANAPC15 | interactor | 3 | 1.000 | 0 | Na_trans_assoc (PF06512, IPR010526): Sodium ion transport-associated ANAPC15 (PF15243, IPR026182): Anaphase-promoting complex subunit 15 |
7 |
ARHGEF2 | oncoprotein | 9 | 0.611 | 3.622 | IncA (PF04156, IPR007285): IncA protein PH (PF00169, IPR001849, SM00233): PH domain RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain) |
8 |
ASS1 | suppressor | 13 | 0.470 | 12.465 | Arginosuc_synth (PF00764, IPR001518): Arginosuccinate synthase |
9 |
BAX | suppressor | 5 | 0.667 | 0.722 | Bcl-2 (PF00452, IPR026298): Apoptosis regulator proteins, Bcl-2 family |
10 |
BTRC | oncoprotein | 13 | 0.364 | 23.596 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Beta-TrCP_D (PF12125, IPR021977, SM01028): D domain of beta-TrCP ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain F-box-like (PF12937, IPR001810): F-box-like |
11 |
CACYBP | interactor | 8 | 0.571 | 2.575 | CS (PF04969, IPR007052): CS domain SGS (PF05002, IPR007699): SGS domain Siah-Interact_N (PF09032, IPR015120): Siah interacting protein, N terminal |
12 |
CALM1 | interactor | 15 | 0.314 | 36.574 | EF-hand_7 (PF13499, IPR011992): EF-hand domain pair |
13 |
CAND1 | interactor | 26 | 0.483 | 52.892 | Adaptin_N (PF01602, IPR002553): Adaptin N terminal region DUF1981 (PF09324, IPR015403): Domain of unknown function (DUF1981) HEAT (PF02985, IPR000357): HEAT repeat TIP120 (PF08623, IPR013932): TATA-binding protein interacting (TIP20) RTP1_C1 (PF10363, IPR019451): Required for nuclear transport of RNA pol II C-terminus 1 DUF3385 (PF11865, IPR024585): Domain of unknown function (DUF3385) MMS19_C (PF12460, IPR024687): RNAPII transcription regulator C-terminal Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region HEAT_EZ (PF13513): HEAT-like repeat HEAT_2 (PF13646): HEAT repeats MMS19_N (PF14500): Dos2-interacting transcription regulator of RNA-Pol-II |
14 |
CAT | suppressor | 10 | 0.556 | 8.017 | Catalase (PF00199, IPR011614, SM01060): Catalase Catalase-rel (PF06628, IPR010582): Catalase-related immune-responsive |
15 |
CCNB1 | oncoprotein | 10 | 0.422 | 9.411 | Adeno_E1A (PF02703, IPR003853): Early E1A protein Cyclin_C (PF02984, IPR004367): Cyclin, C-terminal domain Cyclin_N (PF00134, IPR006671): Cyclin, N-terminal domain |
16 |
CDC42 | oncoprotein | 5 | 0.833 | 0.125 | Ras (PF00071, IPR001806, SM00173): Ras family |
17 |
CDK2 | suppressor | 29 | 0.415 | 64.616 | Kdo (PF06293, IPR010440): Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase (PF00069, IPR000719): Protein kinase domain |
18 |
CFL1 | interactor | 28 | 0.320 | 135.779 | Cofilin_ADF (PF00241, IPR002108, SM00102): Cofilin/tropomyosin-type actin-binding protein |
19 |
CLEC4G | interactor | 1 | 0 | 0 | ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16) Lectin_C (PF00059, IPR001304, SM00034): Lectin C-type domain |
20 |
COPS5 | protein found in more fusions | 25 | 0.591 | 27.050 | JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease |
21 |
COPS6 | interactor | 20 | 0.614 | 24.225 | DUF320 (PF03777, IPR005528): Small secreted domain (DUF320) JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg (PF13012, IPR024969): Maintenance of mitochondrial structure and function |
22 |
CRY1 | interactor | 11 | 0.333 | 13.712 | DNA_photolyase (PF00875, IPR006050): DNA photolyase FAD_binding_7 (PF03441, IPR005101): FAD binding domain of DNA photolyase |
23 |
CUL1 | suppressor | 32 | 0.387 | 118.530 | Cullin (PF00888, IPR001373, SM00182): Cullin family Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain |
24 |
CUL2 | suppressor | 21 | 0.590 | 21.519 | Cullin (PF00888, IPR001373, SM00182): Cullin family Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain |
25 |
CUL3 | protein found in more fusions | 35 | 0.355 | 156.943 | Cullin (PF00888, IPR001373, SM00182): Cullin family Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain WAC_Acf1_DNA_bd (PF10537, IPR013136): ATP-utilising chromatin assembly and remodelling N-terminal |
26 |
CUL4A | protein found in more fusions | 17 | 0.567 | 22.292 | Cullin (PF00888, IPR001373, SM00182): Cullin family Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain |
27 |
CUL4B | oncoprotein | 21 | 0.619 | 18.341 | Cullin (PF00888, IPR001373, SM00182): Cullin family EBP50_C (PF09007, IPR015098): EBP50, C-terminal Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain PG_binding_4 (PF12229, IPR022029): Putative peptidoglycan binding domain MDFI (PF15316, IPR026134): MyoD family inhibitor |
28 |
CUL5 | suppressor | 20 | 0.647 | 14.410 | Cullin (PF00888, IPR001373, SM00182): Cullin family GlutR_dimer (PF00745, IPR015896): Glutamyl-tRNAGlu reductase, dimerisation domain Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain |
29 |
CUL7 | protein found in more fusions | 19 | 0.366 | 25.324 | ANAPC10 (PF03256, IPR004939): Anaphase-promoting complex, subunit 10 (APC10) Cullin (PF00888, IPR001373, SM00182): Cullin family DUF1918 (PF08940, IPR015035): Domain of unknown function (DUF1918) Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain Cul7 (PF11515, IPR021097): Mouse development and cellular proliferation protein Cullin-7 |
30 |
DAB2 | suppressor | 2 | 1.000 | 0 | PID (PF00640, IPR006020, SM00462): Phosphotyrosine interaction domain (PTB/PID) zf-C2H2_assoc3 (PF16637): Putative zinc-finger between two C2H2 zinc-fingers on Patz |
31 |
DAZAP1 | interactor | 25 | 0.303 | 80.326 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2076 (PF09849, IPR018648): Uncharacterized protein conserved in bacteria (DUF2076) |
32 |
DCUN1D1 | interactor | 18 | 0.673 | 11.843 | Cullin_binding (PF03556, IPR005176): Cullin binding UBA_4 (PF14555): UBA-like domain |
33 |
DNPH1 | protein found in more fusions | 3 | 1.000 | 0 | Nuc_deoxyrib_tr (PF05014, IPR007710): Nucleoside 2-deoxyribosyltransferase |
34 |
EGFR | oncoprotein | 25 | 0.319 | 95.504 | Furin-like (PF00757, IPR006211): Furin-like cysteine rich region Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase Recep_L_domain (PF01030, IPR000494): Receptor L domain GAPT (PF11770, IPR021082): GRB2-binding adapter (GAPT) GF_recep_IV (PF14843, IPR032778): Growth factor receptor domain IV |
35 |
EIF4A3 | interactor | 19 | 0.392 | 36.253 | DEAD (PF00270, IPR011545): DEAD/DEAH box helicase Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain |
36 |
EPS15 | oncoprotein | 11 | 0.400 | 14.623 | Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein UIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif DUF3391 (PF11871, IPR021812): Domain of unknown function (DUF3391) EF-hand_4 (PF12763, IPR000261): Cytoskeletal-regulatory complex EF hand EF-hand_7 (PF13499, IPR011992): EF-hand domain pair |
37 |
FERMT3 | interactor | 5 | 0.600 | 1.052 | FERM_M (PF00373, IPR019748): FERM central domain FERM_N (PF09379, IPR018979): FERM N-terminal domain |
38 |
FN1 | oncoprotein | 32 | 0.268 | 169.768 | fn1 (PF00039, IPR000083, SM00058): Fibronectin type I domain fn2 (PF00040, IPR000562, SM00059): Fibronectin type II domain fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369) |
39 |
FSCN1 | oncoprotein | 12 | 0.485 | 11.725 | Fascin (PF06268, IPR022768): Fascin domain |
40 |
FUS | suppressor | 34 | 0.373 | 140.397 | Herpes_PAP (PF03325, IPR004997): Herpesvirus polymerase accessory protein RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SVS_QK (PF10578, IPR018942): Seminal vesicle protein repeat zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others Limkain-b1 (PF11608, IPR024582): Limkain b1 FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 Keratin_2_head (PF16208, IPR032444): Keratin type II head |
41 |
GAN | protein found in more fusions | 4 | 1.000 | 0 | BACK (PF07707, IPR011705, SM00875): BTB And C-terminal Kelch BTB (PF00651, IPR013069, SM00225): BTB/POZ domain Kelch_1 (PF01344, IPR006652, SM00612): Kelch motif Kelch_3 (PF13415): Galactose oxidase, central domain Kelch_5 (PF13854): Kelch motif |
42 |
GAPDH | oncoprotein | 41 | 0.315 | 243.146 | Gp_dh_C (PF02800, IPR020829): Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N (PF00044, IPR020828, SM00846): Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain OstA (PF03968, IPR005653): OstA-like protein |
43 |
HECTD1 | interactor | 4 | 0.667 | 0.500 | Cwf_Cwc_15 (PF04889, IPR006973): Cwf15/Cwc15 cell cycle control protein MIB_HERC2 (PF06701, IPR010606): Mib_herc2 NOA36 (PF06524, IPR010531): NOA36 protein Sad1_UNC (PF07738, IPR012919): Sad1 / UNC-like C-terminal HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase) Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) PBP1_TM (PF14812, IPR032730): Transmembrane domain of transglycosylase PBP1 at N-terminal |
44 |
HNRNPA1 | interactor | 38 | 0.380 | 169.390 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HnRNPA1 (PF11627, IPR021662): Nuclear factor hnRNPA1 |
45 |
IKBKAP | interactor | 10 | 0.556 | 7.889 | IKI3 (PF04762, IPR006849): IKI3 family Clathrin (PF00637, IPR000547, SM00299): Region in Clathrin and VPS MMU163 (PF17119, IPR031342): Mitochondrial protein up-regulated during meiosis |
46 |
IQCB1 | interactor | 7 | 0.286 | 10.065 | DUF1765 (PF08578, IPR013887): Protein of unknown function (DUF1765) IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif HJURP_C (PF12347, IPR022102): Holliday junction regulator protein family C-terminal repeat Condensin2nSMC (PF12422, IPR024741): Condensin II non structural maintenance of chromosomes subunit |
47 |
IRF3 | suppressor | 3 | 1.000 | 0 | IRF (PF00605, IPR001346, SM00348): Interferon regulatory factor transcription factor IRF-3 (PF10401, IPR019471): Interferon-regulatory factor 3 |
48 |
ISG15 | suppressor | 7 | 0.524 | 2.935 | ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family |
49 |
ITGA4 | interactor | 21 | 0.426 | 31.666 | FG-GAP (PF01839, IPR013517): FG-GAP repeat Integrin_alpha (PF00357, IPR018184): Integrin alpha cytoplasmic region Integrin_alpha2 (PF08441, IPR013649): Integrin alpha |
50 |
LAP3 | interactor | 6 | 0.667 | 1.327 | Peptidase_M17 (PF00883, IPR000819): Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N (PF02789, IPR008283): Cytosol aminopeptidase family, N-terminal domain PAW (PF04721, IPR006588, SM00613): PNGase C-terminal domain, mannose-binding module PAW |
51 |
LOC440434 | interactor | 1 | 0 | 0 | NA |
52 |
LUC7L | protein found in more fusions | 6 | 0.700 | 1.233 | LUC7 (PF03194, IPR004882): LUC7 N_terminus Hid1 (PF12722): High-temperature-induced dauer-formation protein |
53 |
MAGOH | interactor | 5 | 0.700 | 1.167 | Mago_nashi (PF02792, IPR004023): Mago nashi protein |
54 |
MCM2 | oncoprotein | 36 | 0.324 | 187.787 | AAA_3 (PF07726, IPR011703): ATPase family associated with various cellular activities (AAA) MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family MCM2_N (PF12619, IPR008045): Mini-chromosome maintenance protein 2 MCM_N (PF14551, IPR027925): MCM N-terminal domain MCM_OB (PF17207): MCM OB domain |
55 |
MCM5 | oncoprotein | 12 | 0.652 | 6.198 | MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family MCM_N (PF14551, IPR027925): MCM N-terminal domain MCM_OB (PF17207): MCM OB domain |
56 |
METTL1 | interactor | 6 | 0.400 | 6.367 | Methyltransf_4 (PF02390, IPR003358): Putative methyltransferase |
57 |
MPG | interactor | 7 | 0.476 | 7.933 | Pur_DNA_glyco (PF02245, IPR003180): Methylpurine-DNA glycosylase (MPG) |
58 |
MPP1 | oncoprotein | 4 | 0.833 | 0.286 | PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) SH3_2 (PF07653, IPR011511): Variant SH3 domain Guanylate_kin (PF00625, IPR008145, SM00072): Guanylate kinase P33MONOX (PF15302, IPR026759): P33 mono-oxygenase |
59 |
MSH6 | oncoprotein | 7 | 0.524 | 3.343 | MutS_I (PF01624, IPR007695): MutS domain I MutS_II (PF05188, IPR007860): MutS domain II PWWP (PF00855, IPR000313, SM00293): PWWP domain MutS_V (PF00488, IPR000432, SM00534): MutS domain V MutS_III (PF05192, IPR007696, SM00533): MutS domain III UPF0524 (PF15823, IPR029670): UPF0524 of C3orf70 |
60 |
MTRNR2L1 | interactor | 1 | 0 | 0 | Humanin (PF15040, IPR028139): Humanin family |
61 |
MYC | oncoprotein | 20 | 0.304 | 63.361 | HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain Myc-LZ (PF02344, IPR003327): Myc leucine zipper domain Myc_N (PF01056, IPR012682): Myc amino-terminal region |
62 |
MYD88 | oncoprotein | 3 | 1.000 | 0 | Death (PF00531, IPR000488, SM00005): Death domain TIR (PF01582, IPR000157, SM00255): TIR domain |
63 |
NANS | interactor | 6 | 0.733 | 0.657 | NeuB (PF03102, IPR013132): NeuB family SAF (PF08666, IPR013974, SM00858): SAF domain |
64 |
NEDD8 | interactor | 24 | 0.494 | 54.004 | ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family |
65 |
NF2 | suppressor | 6 | 0.500 | 2.519 | ERM (PF00769, IPR011259): Ezrin/radixin/moesin family FERM_C (PF09380, IPR018980): FERM C-terminal PH-like domain FERM_M (PF00373, IPR019748): FERM central domain FERM_N (PF09379, IPR018979): FERM N-terminal domain |
66 |
NTRK1 | oncoprotein | 51 | 0.204 | 600.615 | I-set (PF07679, IPR013098): Immunoglobulin I-set domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase LRR_8 (PF13855, IPR001611): Leucine rich repeat TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain |
67 |
OBSL1 | interactor | 17 | 0.450 | 15.133 | BiPBP_C (PF06832, IPR009647): Penicillin-Binding Protein C-terminus Family fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain Herpes_gE (PF02480, IPR003404): Alphaherpesvirus glycoprotein E I-set (PF07679, IPR013098): Immunoglobulin I-set domain V-set (PF07686, IPR013106): Immunoglobulin V-set domain Ig_3 (PF13927): Immunoglobulin domain Ig_4 (PF16680, IPR032052): T-cell surface glycoprotein CD3 delta chain Izumo-Ig (PF16706, IPR032699): Izumo-like Immunoglobulin domain |
68 |
OTUB1 | interactor | 12 | 0.333 | 24.824 | Peptidase_C65 (PF10275, IPR019400): Peptidase C65 Otubain |
69 |
PARK2 | suppressor | 15 | 0.363 | 29.524 | IBR (PF01485, IPR002867, SM00647): IBR domain, a half RING-finger domain ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family |
70 |
PEBP1 | suppressor | 6 | 0.667 | 3.333 | PBP (PF01161, IPR008914): Phosphatidylethanolamine-binding protein |
71 |
PIDD1 | interactor | 2 | 1.000 | 0 | Death (PF00531, IPR000488, SM00005): Death domain ZU5 (PF00791, IPR000906, SM00218): ZU5 domain Peptidase_S68 (PF10461, IPR019502): Peptidase S68 LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies) LRR_8 (PF13855, IPR001611): Leucine rich repeat |
72 |
PPP2R1A | oncoprotein | 18 | 0.340 | 45.488 | TAF6_C (PF07571, IPR011442): TAF6 C-terminal HEAT repeat domain HEAT (PF02985, IPR000357): HEAT repeat HEAT_PBS (PF03130, IPR004155, SM00567): PBS lyase HEAT-like repeat HEAT_2 (PF13646): HEAT repeats |
73 |
PPP2R1B | suppressor | 7 | 0.733 | 1.352 | HEAT (PF02985, IPR000357): HEAT repeat Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region HEAT_2 (PF13646): HEAT repeats |
74 |
PPP2R5D | interactor | 8 | 0.464 | 8.266 | B56 (PF01603, IPR002554): Protein phosphatase 2A regulatory B subunit (B56 family) |
75 |
PPT1 | interactor | 4 | 0.667 | 1.250 | Palm_thioest (PF02089, IPR002472): Palmitoyl protein thioesterase |
76 |
PRDX2 | interactor | 41 | 0.177 | 466.267 | AhpC-TSA (PF00578, IPR000866): AhpC/TSA family 1-cysPrx_C (PF10417, IPR019479): C-terminal domain of 1-Cys peroxiredoxin |
77 |
PRDX3 | interactor | 22 | 0.310 | 57.805 | AhpC-TSA (PF00578, IPR000866): AhpC/TSA family 1-cysPrx_C (PF10417, IPR019479): C-terminal domain of 1-Cys peroxiredoxin |
78 |
PRDX4 | protein found in more fusions | 10 | 0.417 | 9.844 | AhpC-TSA (PF00578, IPR000866): AhpC/TSA family 1-cysPrx_C (PF10417, IPR019479): C-terminal domain of 1-Cys peroxiredoxin |
79 |
PRDX5 | interactor | 15 | 0.333 | 45.286 | Redoxin (PF08534, IPR013740): Redoxin NAD_binding_10 (PF13460, IPR016040): NAD(P)H-binding |
80 |
PRDX6 | protein found in more fusions | 16 | 0.305 | 26.082 | AhpC-TSA (PF00578, IPR000866): AhpC/TSA family 1-cysPrx_C (PF10417, IPR019479): C-terminal domain of 1-Cys peroxiredoxin |
81 |
PRKDC | protein found in more fusions | 32 | 0.258 | 197.379 | FAT (PF02259, IPR003151): FAT domain FATC (PF02260, IPR003152): FATC domain NUC194 (PF08163, IPR012582): NUC194 domain PI3_PI4_kinase (PF00454, IPR000403, SM00146): Phosphatidylinositol 3- and 4-kinase |
82 |
PTEN | suppressor | 5 | 0.500 | 1.397 | DSPc (PF00782, IPR020422, SM00195): Dual specificity phosphatase, catalytic domain PTEN_C2 (PF10409, IPR014020): C2 domain of PTEN tumour-suppressor protein |
83 |
RAB4B | oncoprotein | 1 | 0 | 0 | Ras (PF00071, IPR001806, SM00173): Ras family |
84 |
RAD23A | oncoprotein | 8 | 0.381 | 10.833 | UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain XPC-binding (PF09280, IPR015360): XPC-binding domain ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family |
85 |
RAD52 | oncoprotein | 8 | 0.810 | 0.924 | Rad52_Rad22 (PF04098, IPR007232): Rad52/22 family double-strand break repair protein DUF2335 (PF10097, IPR019284): Predicted membrane protein (DUF2335) |
86 |
RNH1 | suppressor | 6 | 0.600 | 2.139 | LRR_1 (PF00560, IPR001611): Leucine Rich Repeat Metallothio_Euk (PF12749, IPR024306): Eukaryotic metallothionein LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies) LRR_6 (PF13516, IPR001611): Leucine Rich repeat |
87 |
RPA1 | suppressor | 23 | 0.424 | 61.923 | Rep-A_N (PF04057, IPR007199): Replication factor-A protein 1, N-terminal domain Rep_fac-A_C (PF08646, IPR013955): Replication factor-A C terminal domain tRNA_anti-codon (PF01336, IPR004365): OB-fold nucleic acid binding domain REPA_OB_2 (PF16900, IPR031657): Replication protein A OB domain |
88 |
RPA2 | oncoprotein | 21 | 0.419 | 53.137 | RPA_C (PF08784, IPR014892): Replication protein A C terminal tRNA_anti-codon (PF01336, IPR004365): OB-fold nucleic acid binding domain RMI2 (PF16100, IPR032245): RecQ-mediated genome instability protein 2 |
89 |
RPA3 | interactor | 18 | 0.500 | 23.201 | Rep_fac-A_3 (PF08661, IPR013970): Replication factor A protein 3 |
90 |
RPS6KB2 | interactor | 7 | 0.619 | 2.833 | Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain |
91 |
SESN1 | interactor | 1 | 0 | 0 | PA26 (PF04636, IPR006730): PA26 p53-induced protein (sestrin) |
92 |
SESN2 | interactor | 1 | 0 | 0 | PA26 (PF04636, IPR006730): PA26 p53-induced protein (sestrin) |
93 |
SH2D1B | interactor | 1 | 0 | 0 | SH2 (PF00017, IPR000980, SM00252): SH2 domain |
94 |
SH3BGRL2 | oncoprotein | 2 | 1.000 | 0 | SH3BGR (PF04908, IPR006993): SH3-binding, glutamic acid-rich protein |
95 |
SHC1 | oncoprotein | 7 | 0.933 | 0.400 | PID (PF00640, IPR006020, SM00462): Phosphotyrosine interaction domain (PTB/PID) SH2 (PF00017, IPR000980, SM00252): SH2 domain |
96 |
SKI | oncoprotein | 3 | 1.000 | 0 | c-SKI_SMAD_bind (PF08782, IPR014890, SM01046): c-SKI Smad4 binding domain Ski_Sno (PF02437, IPR003380): SKI/SNO/DAC family SlyX (PF04102, IPR007236): SlyX HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1 |
97 |
SMARCD1 | interactor | 3 | 0.667 | 0.400 | ATP-synt_G (PF04718, IPR006808): Mitochondrial ATP synthase g subunit DivIC (PF04977, IPR007060): Septum formation initiator SWIB (PF02201, IPR003121, SM00151): SWIB/MDM2 domain |
98 |
SNCA | interactor | 10 | 0.472 | 9.093 | Synuclein (PF01387, IPR001058): Synuclein |
99 |
SOD1 | interactor | 14 | 0.462 | 22.290 | Sod_Cu (PF00080, IPR001424): Copper/zinc superoxide dismutase (SODC) |
100 |
SPR | interactor | 9 | 0.528 | 7.266 | adh_short (PF00106, IPR002198): short chain dehydrogenase |
101 |
SUZ12 | suppressor | 9 | 0.357 | 9.495 | DUF2070 (PF09843, IPR019204): Predicted membrane protein (DUF2070) VEFS-Box (PF09733, IPR019135): VEFS-Box of polycomb protein |
102 |
TANGO2 | interactor | 5 | 0.900 | 0.250 | TANGO2 (PF05742, IPR008551): Transport and Golgi organisation 2 |
103 |
TERF1 | interactor | 14 | 0.346 | 28.700 | TRF (PF08558, IPR013867): Telomere repeat binding factor (TRF) Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain |
104 |
TIPIN | interactor | 3 | 1.000 | 0 | ERM (PF00769, IPR011259): Ezrin/radixin/moesin family Swi3 (PF07962, IPR012923): Replication Fork Protection Component Swi3 CEP19 (PF14933, IPR029412): CEP19-like protein |
105 |
TIPRL | interactor | 6 | 0.667 | 1.507 | TIP41 (PF04176, IPR007303): TIP41-like family |
106 |
TKT | protein found in more fusions | 23 | 0.372 | 63.679 | Transket_pyr (PF02779, IPR005475, SM00861): Transketolase, pyrimidine binding domain Transketolase_C (PF02780, IPR005476): Transketolase, C-terminal domain Transketolase_N (PF00456, IPR005474): Transketolase, thiamine diphosphate binding domain |
107 |
TPM3 | oncoprotein | 11 | 0.422 | 5.066 | Tropomyosin (PF00261, IPR000533): Tropomyosin Tropomyosin_1 (PF12718, IPR000533): Tropomyosin like |
108 |
TRIM4 | protein found in more fusions | 2 | 0 | 0 | SPRY (PF00622, IPR003877, SM00449): SPRY domain zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger Fasciclin (PF02469, IPR000782, SM00554): Fasciclin domain PRY (PF13765, IPR006574, SM00589): SPRY-associated domain Ubiquitin_2 (PF14560, IPR027933): Ubiquitin-like domain zf-C3HC4_4 (PF15227): zinc finger of C3HC4-type, RING |
109 |
TSNAX | interactor | 3 | 0.667 | 1.000 | Translin (PF01997, IPR002848): Translin family |
110 |
TXN | oncoprotein | 24 | 0.322 | 102.812 | Thioredoxin (PF00085, IPR013766): Thioredoxin |
111 |
U2AF2 | protein found in more fusions | 22 | 0.424 | 49.864 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Transformer (PF06495, IPR010519): Fruit fly transformer protein |
112 |
UBE2H | protein found in more fusions | 5 | 0.500 | 1.567 | UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme Uteroglobin (PF01099, IPR016126, SM00096): Uteroglobin family |
113 |
UBE2M | interactor | 16 | 0.448 | 14.408 | UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme |
114 |
UBE3A | oncoprotein | 8 | 0.429 | 7.752 | HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase) PCM1_C (PF15717, IPR031446): Pericentriolar material 1 C terminus AZUL (PF16558, IPR032353): Amino-terminal Zinc-binding domain of ubiquitin ligase E3A |
115 |
UBL4A | interactor | 5 | 0.600 | 1.376 | ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family |
116 |
UCHL5 | oncoprotein | 12 | 0.382 | 17.176 | Peptidase_C12 (PF01088, IPR001578): Ubiquitin carboxyl-terminal hydrolase, family 1 |
117 |
URM1 | interactor | 3 | 0.667 | 0.667 | Urm1 (PF09138, IPR015221): Urm1 (Ubiquitin related modifier) |
118 |
USP5 | interactor | 5 | 0.400 | 4.400 | UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase zf-UBP (PF02148, IPR001607, SM00290): Zn-finger in ubiquitin-hydrolases and other protein |
119 |
VCAM1 | interactor | 20 | 0.347 | 37.234 | C2-set (PF05790, IPR008424): Immunoglobulin C2-set domain I-set (PF07679, IPR013098): Immunoglobulin I-set domain ig (PF00047, IPR013151, SM00409): Immunoglobulin domain V-set (PF07686, IPR013106): Immunoglobulin V-set domain Ig_3 (PF13927): Immunoglobulin domain |
120 |
VHL | suppressor | 14 | 0.526 | 11.082 | Trypan_PARP (PF05887, IPR008882): Procyclic acidic repetitive protein (PARP) VHL (PF01847, IPR022772): von Hippel-Lindau disease tumour suppressor protein VHL_C (PF17211): VHL box domain |
121 |
YAP1 | suppressor | 9 | 0.361 | 18.800 | Bindin (PF02084, IPR000775): Bindin WW (PF00397, IPR001202, SM00456): WW domain GspL_C (PF12693, IPR025691): GspL periplasmic domain FAM181 (PF15238, IPR029359): FAM181 |
122 |
YWHAQ | interactor | 30 | 0.301 | 174.826 | 14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein |
123 |
ZFR | interactor | 11 | 0.527 | 8.151 | DZF (PF07528, IPR006561, SM00572): DZF domain K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein ANAPC_CDC26 (PF10471, IPR018860): Anaphase-promoting complex APC subunit CDC26 TAT_signal (PF10518, IPR019546): TAT (twin-arginine translocation) pathway signal sequence zf-met (PF12874): Zinc-finger of C2H2 type |