1 |
POU2F1 | parental protein | 54 | 0.106 | 1959.664 | Pou (PF00157, IPR000327, SM00352): Pou domain - N-terminal to homeobox domain Homeobox (PF00046, IPR001356, SM00389): Homeobox domain DUF3597 (PF12200, IPR022016): Domain of unknown function (DUF3597) |
2 |
APP | protein found in more fusions | 11 | 0.267 | 32.167 | APP_N (PF02177, IPR015849, SM00006): Amyloid A4 N-terminal heparin-binding Beta-APP (PF03494, IPR013803): Beta-amyloid peptide (beta-APP) BUD22 (PF09073, IPR015158): BUD22 IncA (PF04156, IPR007285): IncA protein Kunitz_BPTI (PF00014, IPR002223, SM00131): Kunitz/Bovine pancreatic trypsin inhibitor domain APP_amyloid (PF10515, IPR019543): beta-amyloid precursor protein C-terminus APP_Cu_bd (PF12924, IPR011178): Copper-binding of amyloid precursor, CuBD APP_E2 (PF12925, IPR024329): E2 domain of amyloid precursor protein |
3 |
AR | oncoprotein | 12 | 0.545 | 11.140 | Androgen_recep (PF02166, IPR001103): Androgen receptor zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor |
4 |
BRCA1 | suppressor | 17 | 0.458 | 43.358 | BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger) BRCT_assoc (PF12820, IPR025994): Serine-rich domain associated with BRCT |
5 |
BRD7 | suppressor | 2 | 1.000 | 0 | HcyBio (PF01837, IPR002708): Homocysteine biosynthesis enzyme, sulfur-incorporation GntR (PF00392, IPR000524, SM00345): Bacterial regulatory proteins, gntR family Presenilin (PF01080, IPR001108): Presenilin Bromodomain (PF00439, IPR001487, SM00297): Bromodomain DUF3512 (PF12024, IPR021900): Domain of unknown function (DUF3512) MAJIN (PF15077, IPR027816): Membrane-anchored junction protein |
6 |
CDK11B | oncoprotein | 5 | 0.667 | 1.167 | DDHD (PF02862, IPR004177, SM01127): DDHD domain DivIC (PF04977, IPR007060): Septum formation initiator Pkinase (PF00069, IPR000719): Protein kinase domain DUF4748 (PF15932, IPR031833): Domain of unknown function (DUF4748) |
7 |
CEBPE | interactor | 2 | 0 | 0 | Myc-LZ (PF02344, IPR003327): Myc leucine zipper domain bZIP_2 (PF07716, IPR004827, SM00338): Basic region leucine zipper |
8 |
CREB1 | oncoprotein | 10 | 0.333 | 18.967 | bZIP_1 (PF00170, IPR004827): bZIP transcription factor pKID (PF02173, IPR003102): pKID domain DUF4988 (PF16378, IPR032149): Domain of unknown function |
9 |
ESR1 | suppressor | 19 | 0.386 | 67.415 | Oest_recep (PF02159, IPR001292): Oestrogen receptor zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor ESR1_C (PF12743, IPR024736): Oestrogen-type nuclear receptor final C-terminal |
10 |
FOXC1 | suppressor | 5 | 0.500 | 4.167 | TAT_signal (PF10518, IPR019546): TAT (twin-arginine translocation) pathway signal sequence Forkhead (PF00250, IPR001766, SM00339): Forkhead domain PAF (PF15715, IPR031444): PCNA-associated factor PRIMA1 (PF16101): Proline-rich membrane anchor 1 |
11 |
FOXC2 | oncoprotein | 5 | 0.667 | 1.667 | Forkhead (PF00250, IPR001766, SM00339): Forkhead domain PRIMA1 (PF16101): Proline-rich membrane anchor 1 |
12 |
FOXS1 | interactor | 4 | 0.500 | 2.667 | Forkhead (PF00250, IPR001766, SM00339): Forkhead domain |
13 |
GAPDH | oncoprotein | 8 | 0.524 | 7.248 | Gp_dh_C (PF02800, IPR020829): Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N (PF00044, IPR020828, SM00846): Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain OstA (PF03968, IPR005653): OstA-like protein |
14 |
HCFC1 | protein found in more fusions | 5 | 0.667 | 0.733 | fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain Kelch_1 (PF01344, IPR006652, SM00612): Kelch motif Kelch_3 (PF13415): Galactose oxidase, central domain Kelch_5 (PF13854): Kelch motif zf-tcix (PF14952, IPR029269): Putative treble-clef, zinc-finger, Zn-binding |
15 |
HDAC1 | suppressor | 16 | 0.448 | 35.487 | FSAP_sig_propep (PF03032, IPR004275): Frog skin active peptide family signal and propeptide Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain |
16 |
HMGA1 | oncoprotein | 8 | 0.464 | 9.206 | AT_hook (PF02178, IPR017956, SM00384): AT hook motif DUF2239 (PF09998, IPR018715): Uncharacterized protein conserved in bacteria (DUF2239) |
17 |
HOXB13 | suppressor | 4 | 0.500 | 2.667 | Homeobox (PF00046, IPR001356, SM00389): Homeobox domain HoxA13_N (PF12284, IPR022067): Hox protein A13 N terminal |
18 |
HOXC4 | interactor | 4 | 0.667 | 1.667 | Homeobox (PF00046, IPR001356, SM00389): Homeobox domain |
19 |
HOXC9 | interactor | 2 | 1.000 | 0 | Hox9_act (PF04617, IPR006711): Hox9 activation region Homeobox (PF00046, IPR001356, SM00389): Homeobox domain |
20 |
HSPA8 | oncoprotein | 11 | 0.382 | 28.500 | HSP70 (PF00012, IPR013126): Hsp70 protein |
21 |
IRF9 | interactor | 4 | 0.500 | 3.000 | IRF (PF00605, IPR001346, SM00348): Interferon regulatory factor transcription factor IRF-3 (PF10401, IPR019471): Interferon-regulatory factor 3 |
22 |
LMNB1 | interactor | 2 | 1.000 | 0 | Filament (PF00038, IPR001664): Intermediate filament protein LTD (PF00932, IPR001322): Lamin Tail Domain |
23 |
MAGEA10 | interactor | 1 | 0 | 0 | MAGE (PF01454, IPR002190): MAGE family SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein MAGE_N (PF12440, IPR021072): Melanoma associated antigen family N terminal |
24 |
MNAT1 | oncoprotein | 4 | 1.000 | 0 | MAT1 (PF06391, IPR015877): CDK-activating kinase assembly factor MAT1 Mu-like_Com (PF10122, IPR019294): Mu-like prophage protein Com zf-C3HC4_5 (PF17121, IPR001841): Zinc finger, C3HC4 type (RING finger) |
25 |
NCOR2 | oncoprotein | 13 | 0.449 | 20.984 | CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal MAS20 (PF02064, IPR002056): MAS20 protein import receptor OAD_gamma (PF04277, IPR005899): Oxaloacetate decarboxylase, gamma chain PSK (PF06404, IPR009438): Phytosulfokine precursor protein (PSK) SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360) Gti1_Pac2 (PF09729, IPR018608): Gti1/Pac2 family PRCC (PF10253, IPR018800): Mitotic checkpoint regulator, MAD2B-interacting Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain Spt20 (PF12090, IPR021950): Spt20 family DUF3915 (PF13054, IPR025026): Protein of unknown function (DUF3915) DUF4518 (PF15008, IPR026698): Domain of unknown function (DUF4518) GPS2_interact (PF15784, IPR031557): G-protein pathway suppressor 2-interacting domain DUF4820 (PF16091, IPR032150): Domain of unknown function (DUF4820) |
26 |
NPAT | interactor | 3 | 1.000 | 0 | Rxt3 (PF08642, IPR013951): Histone deacetylation protein Rxt3 TERB2 (PF15101, IPR028065): Telomere-associated protein TERB2 NPAT_C (PF15712, IPR031442): NPAT C terminus |
27 |
NR3C1 | protein found in more fusions | 11 | 0.378 | 20.817 | GCR (PF02155, IPR001409): Glucocorticoid receptor zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor |
28 |
PARP1 | suppressor | 14 | 0.615 | 13.243 | BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain PADR1 (PF08063, IPR012982): PADR1 (NUC008) domain PARP (PF00644, IPR012317): Poly(ADP-ribose) polymerase catalytic domain PARP_reg (PF02877, IPR004102): Poly(ADP-ribose) polymerase, regulatory domain WGR (PF05406, IPR008893, SM00773): WGR domain zf-PARP (PF00645, IPR001510): Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region |
29 |
PBX1 | oncoprotein | 5 | 0.500 | 4.333 | PBC (PF03792, IPR005542): PBC domain Homeobox (PF00046, IPR001356, SM00389): Homeobox domain |
30 |
PGR | suppressor | 12 | 0.673 | 10.563 | Prog_receptor (PF02161, IPR000128): Progesterone receptor zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor |
31 |
PKNOX1 | suppressor | 3 | 0.667 | 1.000 | Homeobox_KN (PF05920, IPR008422): Homeobox KN domain Meis_PKNOX_N (PF16493, IPR032453): N-terminal of Homeobox Meis and PKNOX1 |
32 |
PLK3 | interactor | 1 | 0 | 0 | Pkinase (PF00069, IPR000719): Protein kinase domain POLO_box (PF00659, IPR000959): POLO box duplicated region |
33 |
POGZ | interactor | 4 | 0.500 | 1.733 | DDE_1 (PF03184, IPR004875): DDE superfamily endonuclease Rubredoxin (PF00301, IPR024935): Rubredoxin HTH_Tnp_Tc5 (PF03221, IPR006600, SM00674): Tc5 transposase DNA-binding domain zf-RRN7 (PF11781, IPR021752): Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain HTH_28 (PF13518): Helix-turn-helix domain zinc_ribbon_4 (PF13717): zinc-ribbon domain zf-C2H2_4 (PF13894): C2H2-type zinc finger zf-C2H2_6 (PF13912, IPR007087): C2H2-type zinc finger zf-RING_5 (PF14634, IPR001841): zinc-RING finger domain |
34 |
POU2AF1 | oncoprotein | 1 | 0 | 0 | PD-C2-AF1 (PF09310, IPR015389): POU domain, class 2, associating factor 1 |
35 |
PRKACA | interactor | 4 | 0.833 | 0.400 | Pkinase (PF00069, IPR000719): Protein kinase domain |
36 |
PRKDC | protein found in more fusions | 14 | 0.615 | 13.222 | FAT (PF02259, IPR003151): FAT domain FATC (PF02260, IPR003152): FATC domain NUC194 (PF08163, IPR012582): NUC194 domain PI3_PI4_kinase (PF00454, IPR000403, SM00146): Phosphatidylinositol 3- and 4-kinase |
37 |
RARA | oncoprotein | 8 | 0.762 | 1.789 | zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor |
38 |
RELA | oncoprotein | 17 | 0.483 | 37.523 | DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region RHD_DNA_bind (PF00554, IPR011539): Rel homology DNA-binding domain RHD_dimer (PF16179, IPR032397): Rel homology dimerisation domain |
39 |
RXRA | oncoprotein | 9 | 0.571 | 6.717 | zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor Nuc_recep-AF1 (PF11825, IPR021780): Nuclear/hormone receptor activator site AF-1 |
40 |
SNAPC4 | interactor | 2 | 1.000 | 0 | DUF111 (PF01969, IPR002822): Protein of unknown function DUF111 Filament_head (PF04732, IPR006821): Intermediate filament head (DNA binding) region SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain Myb_DNA-bind_6 (PF13921): Myb-like DNA-binding domain |
41 |
SP1 | protein found in more fusions | 19 | 0.405 | 61.556 | zf-Di19 (PF05605, IPR008598): Drought induced 19 protein (Di19), zinc-binding Herpes_capsid (PF06112, IPR009299): Gammaherpesvirus capsid protein zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type Miga (PF10265, IPR019392): Mitoguardin zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 |
42 |
SP4 | interactor | 2 | 1.000 | 0 | zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360) Macoilin (PF09726, IPR019130): Transmembrane protein PAT1 (PF09770, IPR019167): Topoisomerase II-associated protein PAT1 DUF3446 (PF11928, IPR021849): Domain of unknown function (DUF3446) zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_4 (PF13894): C2H2-type zinc finger SEEEED (PF14797, IPR029394): Serine-rich region of AP3B1, clathrin-adaptor complex |
43 |
SPTBN1 | suppressor | 2 | 1.000 | 0 | CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain COG2 (PF06148, IPR024602): COG (conserved oligomeric Golgi) complex component, COG2 DUF1764 (PF08576, IPR013885): Eukaryotic protein of unknown function (DUF1764) Spectrin (PF00435, IPR002017): Spectrin repeat PH_9 (PF15410): Pleckstrin homology domain |
44 |
STAT5B | oncoprotein | 5 | 0.500 | 2.400 | SH2 (PF00017, IPR000980, SM00252): SH2 domain STAT_alpha (PF01017, IPR013800): STAT protein, all-alpha domain STAT_bind (PF02864, IPR013801): STAT protein, DNA binding domain STAT_int (PF02865, IPR013799, SM00964): STAT protein, protein interaction domain |
45 |
STIP1 | interactor | 5 | 0.800 | 1.333 | TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat TPR_9 (PF13371, IPR011990): Tetratricopeptide repeat TPR_11 (PF13414, IPR011990): TPR repeat TPR_12 (PF13424): Tetratricopeptide repeat TPR_17 (PF13431): Tetratricopeptide repeat Wtap (PF17098, IPR029732): Pre-mRNA-splicing regulator WTAP |
46 |
TBP | interactor | 10 | 0.583 | 9.815 | TBP (PF00352, IPR000814): Transcription factor TFIID (or TATA-binding protein, TBP) EPL1 (PF10513, IPR019542): Enhancer of polycomb-like Med3 (PF11593, IPR020998): Mediator complex subunit 3 fungal |
47 |
TEAD2 | interactor | 3 | 0.667 | 1.000 | TEA (PF01285, IPR000818, SM00426): TEA/ATTS domain family |
48 |
THRA | suppressor | 8 | 0.619 | 4.106 | C1_2 (PF03107, IPR004146): C1 domain zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor |
49 |
TLX2 | interactor | 2 | 1.000 | 0 | Homeobox (PF00046, IPR001356, SM00389): Homeobox domain |
50 |
TNF | oncoprotein | 2 | 0 | 0 | TNF (PF00229, IPR006052, SM00207): TNF(Tumour Necrosis Factor) family |
51 |
TXNRD1 | interactor | 2 | 1.000 | 0 | Glutaredoxin (PF00462, IPR002109): Glutaredoxin Pyr_redox_2 (PF07992, IPR023753): Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim (PF02852, IPR004099): Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain |
52 |
VDR | suppressor | 6 | 0.500 | 2.917 | zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor |
53 |
XRCC5 | suppressor | 11 | 0.689 | 6.815 | Ku (PF02735, IPR006164, SM00559): Ku70/Ku80 beta-barrel domain Ku_C (PF03730, IPR005160): Ku70/Ku80 C-terminal arm Ku_N (PF03731, IPR005161): Ku70/Ku80 N-terminal alpha/beta domain Ku_PK_bind (PF08785, IPR014893): Ku C terminal domain like |
54 |
XRCC6 | oncoprotein | 12 | 0.600 | 10.848 | Ku (PF02735, IPR006164, SM00559): Ku70/Ku80 beta-barrel domain Ku_C (PF03730, IPR005160): Ku70/Ku80 C-terminal arm Ku_N (PF03731, IPR005161): Ku70/Ku80 N-terminal alpha/beta domain SAP (PF02037, IPR003034, SM00513): SAP domain |