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Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)111
The number (and %) of the onco-proteins16 (14.41 %)
The number (and %) of the tumor suppressors5 (4.50 %)
Total number of binary PPIs (saturation %)833 (13.64 %)
The number (and %) of affected PPIs126 (15.13 %)
The number of possible different fusions11
PPI diameter3
PPI radius2
The average degree of PPI14.450
Assortativity coefficient-0.1953
The network average Clustering coefficient0.537
The number (and %) of a zero Clustering coefficients16 (14.41 %)
The number (and %) of a zero Betweenness Centrality21 (18.92 %)

ACTIVE INTERACTORS


List of the fusions

PPI for parental proteins: PIH1D1,POLR2F All fusions
Proteins found in more fusions POLR2F/PIH1D1 (see 1 fusions); URI1 (see 2 fusions); APP (see 4 fusions); HSP90AA1 (see 2 fusions); OFD1 (see 1 fusions); RBPMS (see 2 fusions); POLR2E (see 2 fusions); KMT2A (see 16 fusions); POLR2A (see 2 fusions); SDC2 (see 2 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 PIH1D1parental protein570.1763128.313PIH1 (PF08190, IPR012981): pre-RNA processing PIH1/Nop17
2 POLR2Fparental protein700.1763674.269RNA_pol_Rpb6 (PF01192, IPR006110): RNA polymerase Rpb6
3 AKAP2interactor21.0000DUF4407 (PF14362, IPR025519): Domain of unknown function (DUF4407)
AKAP2_C (PF15304, IPR029304): A-kinase anchor protein 2 C-terminus
4 APPprotein found in more fusions150.242124.456APP_N (PF02177, IPR015849, SM00006): Amyloid A4 N-terminal heparin-binding
Beta-APP (PF03494, IPR013803): Beta-amyloid peptide (beta-APP)
BUD22 (PF09073, IPR015158): BUD22
IncA (PF04156, IPR007285): IncA protein
Kunitz_BPTI (PF00014, IPR002223, SM00131): Kunitz/Bovine pancreatic trypsin inhibitor domain
APP_amyloid (PF10515, IPR019543): beta-amyloid precursor protein C-terminus
APP_Cu_bd (PF12924, IPR011178): Copper-binding of amyloid precursor, CuBD
APP_E2 (PF12925, IPR024329): E2 domain of amyloid precursor protein
5 BAG5interactor100BAG (PF02179, IPR003103, SM00264): BAG domain
PDGF_N (PF04692, IPR006782): Platelet-derived growth factor, N terminal region
RRF (PF01765, IPR023584): Ribosome recycling factor
6 BDP1interactor21.0000SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal
Eapp_C (PF10238, IPR019370): E2F-associated phosphoprotein
DUF2917 (PF11142, IPR021317): Protein of unknown function (DUF2917)
UPF0542 (PF15086, IPR027877): Uncharacterised protein family UPF0542
Myb_DNA-bind_7 (PF15963): Myb DNA-binding like
7 CA4interactor100Carb_anhydrase (PF00194, IPR001148, SM01057): Eukaryotic-type carbonic anhydrase
8 CD3EAPinteractor80.7147.463Pol_alpha_B_N (PF08418, IPR013627): DNA polymerase alpha subunit B N-terminal
RNA_polI_A34 (PF08208, IPR013240): DNA-directed RNA polymerase I subunit RPA34.5
9 CRCPinteractor130.79513.324RNA_pol_Rpb4 (PF03874, IPR005574): RNA polymerase Rpb4
Muted (PF14942, IPR017243): Organelle biogenesis, Muted-like protein
10 CTDP1interactor150.57127.776Biotin_lipoyl (PF00364, IPR000089): Biotin-requiring enzyme
FCP1_C (PF09309, IPR015388): FCP1, C-terminal
NIF (PF03031, IPR004274): NLI interacting factor-like phosphatase
SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal
Apt1 (PF10351, IPR019443): Golgi-body localisation protein domain
TFIIE-A_C (PF11521, IPR021600): C-terminal general transcription factor TFIIE alpha
CAF1A (PF12253, IPR022043): Chromatin assembly factor 1 subunit A
PTCB-BRCT (PF12738, IPR001357): twin BRCT domain
HlyD_D23 (PF16576, IPR032317): Barrel-sandwich domain of CusB or HlyD membrane-fusion
11 DCAF4interactor100WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
DUF4221 (PF13970, IPR025316): Domain of unknown function (DUF4221)
12 DCAF6interactor31.0000Herpes_pp85 (PF04637, IPR006731): Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25)
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
DUF3408 (PF11888, IPR021823): Protein of unknown function (DUF3408)
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
ATAD4 (PF15321, IPR028237): ATPase family AAA domain containing 4
MRI (PF15325, IPR028278): Modulator of retrovirus infection
WD40_like (PF17005, IPR031544): WD40-like domain
13 DNTTIP1interactor301.389DUF4385 (PF14328, IPR025494): Domain of unknown function (DUF4385)
14 DOCK7interactor40.6674.816DHR-2 (PF06920, IPR010703): Dock homology region 2
DUF3398 (PF11878, IPR021816): Domain of unknown function (DUF3398)
DOCK-C2 (PF14429, IPR027007): C2 domain in Dock180 and Zizimin proteins
DOCK_N (PF16172, IPR032376): DOCK N-terminus
15 DYNC2LI1interactor100DLIC (PF05783, IPR022780): Dynein light intermediate chain (DLIC)
16 ECDinteractor40.6671.095Bradykinin (PF06753, IPR009608): Bradykinin
SGT1 (PF07093, IPR010770): SGT1 protein
17 ESR1suppressor270.462146.520Oest_recep (PF02159, IPR001292): Oestrogen receptor
zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains)
Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
ESR1_C (PF12743, IPR024736): Oestrogen-type nuclear receptor final C-terminal
18 FBLinteractor70.52442.954Fibrillarin (PF01269, IPR000692): Fibrillarin
19 GCOM1interactor100BRE1 (PF08647, IPR013956): BRE1 E3 ubiquitin ligase
DUF148 (PF02520, IPR003677): Domain of unknown function DUF148
Neur_chan_memb (PF02932, IPR006029): Neurotransmitter-gated ion-channel transmembrane region
OmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like)
GPHR_N (PF12537, IPR022535): The Golgi pH Regulator (GPHR) Family N-terminal
GAS (PF13851, IPR025593): Growth-arrest specific micro-tubule binding
GCOM2 (PF15328, IPR026213): Putative GRINL1B complex locus protein 2
Lebercilin (PF15619, IPR028933): Ciliary protein causing Leber congenital amaurosis disease
20 GPN1interactor170.61824.291ATP_bind_1 (PF03029, IPR004130): Conserved hypothetical ATP binding protein
NB-ARC (PF00931, IPR002182): NB-ARC domain
21 GPN3interactor260.455127.994ATP_bind_1 (PF03029, IPR004130): Conserved hypothetical ATP binding protein
22 GTF2Binteractor140.59341.729Cyclin_C (PF02984, IPR004367): Cyclin, C-terminal domain
TFIIB (PF00382, IPR013150): Transcription factor TFIIB repeat
TF_Zn_Ribbon (PF08271, IPR013137): TFIIB zinc-binding
23 GTF2F1interactor110.8185.440TFIIF_alpha (PF05793, IPR008851): Transcription initiation factor IIF, alpha subunit (TFIIF-alpha)
24 GTF2F2interactor150.71415.710TFIIF_beta (PF02270, IPR003196): Transcription initiation factor IIF, beta subunit
25 GTF3C1interactor40.33315.717B-block_TFIIIC (PF04182, IPR007309): B-block binding subunit of TFIIIC
26 HSP90AA1oncoprotein170.267115.738HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
HSP90 (PF00183, IPR001404): Hsp90 protein
27 IFT122interactor100CENP-B_dimeris (PF09026, IPR015115): Centromere protein B dimerisation domain
Coatomer_WDAD (PF04053, IPR006692): Coatomer WD associated region
Mad3_BUB1_I (PF08311, IPR013212, SM00777): Mad3/BUB1 homology region 1
TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Clathrin (PF00637, IPR000547, SM00299): Region in Clathrin and VPS
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
TPR_7 (PF13176, IPR019734): Tetratricopeptide repeat
zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
zinc_ribbon_9 (PF14369): zinc-ribbon
PHTB1_N (PF14727, IPR028073): PTHB1 N-terminus
28 IL15RAinteractor100NA
29 KDM3Asuppressor100C1_2 (PF03107, IPR004146): C1 domain
JmjC (PF02373, IPR003347, SM00558): JmjC domain, hydroxylase
30 KEAP1oncoprotein60.20024.735BACK (PF07707, IPR011705, SM00875): BTB And C-terminal Kelch
BTB (PF00651, IPR013069, SM00225): BTB/POZ domain
Kelch_1 (PF01344, IPR006652, SM00612): Kelch motif
31 KMT2Aoncoprotein31.0000AT_hook (PF02178, IPR017956, SM00384): AT hook motif
DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777)
FYRC (PF05965, IPR003889, SM00542): F/Y rich C-terminus
FYRN (PF05964, IPR003888, SM00541): F/Y-rich N-terminus
Peptidase_S49_N (PF08496, IPR013703): Peptidase family S49 N-terminal
PHD (PF00628, IPR019787, SM00249): PHD-finger
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
RNA_pol_Rpc4 (PF05132, IPR007811): RNA polymerase III RPC4
SET (PF00856, IPR001214, SM00317): SET domain
zf-CXXC (PF02008, IPR002857): CXXC zinc finger domain
SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein
Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
zf-HC5HC2H (PF13771): PHD-like zinc-binding domain
DUF4834 (PF16118, IPR032272): Domain of unknown function (DUF4834)
32 LRCH3interactor30.6671.118CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
LRR_1 (PF00560, IPR001611): Leucine Rich Repeat
LRR_8 (PF13855, IPR001611): Leucine rich repeat
33 MAP3K4suppressor200CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
Pkinase (PF00069, IPR000719): Protein kinase domain
PLU-1 (PF08429, IPR013637): PLU-1-like protein
Radial_spoke_3 (PF06098, IPR009290): Radial spoke protein 3
DUF3682 (PF12446, IPR022152): Protein of unknown function (DUF3682)
DUF3958 (PF13125, IPR025014): Protein of unknown function (DUF3958)
34 MAPK6oncoprotein200Pkinase (PF00069, IPR000719): Protein kinase domain
35 MAST3interactor100DUF1908 (PF08926, IPR015022): Domain of unknown function (DUF1908)
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
Pkinase (PF00069, IPR000719): Protein kinase domain
ACTL7A_N (PF16840, IPR031769): Actin-like protein 7A N-terminus
36 MED1interactor150.7808.627Vfa1 (PF08432, IPR013640): AAA-ATPase Vps4-associated protein 1
Med1 (PF10744, IPR019680): Mediator of RNA polymerase II transcription subunit 1
DUF4614 (PF15391, IPR027884): Domain of unknown function (DUF4614)
PNISR (PF15996, IPR031937): Arginine/serine-rich protein PNISR
37 MED10interactor210.73319.722Med10 (PF09748, IPR019145): Transcription factor subunit Med10 of Mediator complex
38 MED15interactor100.8890.982Med15 (PF09606, IPR019087): ARC105 or Med15 subunit of Mediator complex non-fungal
39 MED19interactor230.65435.208Med19 (PF10278, IPR019403): Mediator of RNA pol II transcription subunit 19
40 MED25interactor110.8002.179Med25 (PF11232, IPR021394): Mediator complex subunit 25 PTOV activation and synapsin 2
Med25_SD1 (PF11235, IPR021397): Mediator complex subunit 25 synapsin 1
Med25_NR-box (PF11244, IPR021406): Mediator complex subunit 25 C-terminal NR box-containing
Med25_VWA (PF11265, IPR021419): Mediator complex subunit 25 von Willebrand factor type A
41 MED26interactor220.69324.670Med26 (PF08711, IPR017923): TFIIS helical bundle-like domain
Med26_C (PF15693, IPR031416): Mediator complex subunit 26 C-terminal
Med26_M (PF15694, IPR031417): Mediator complex subunit 26 middle domain
42 MED29interactor210.71619.782Med29 (PF11568, IPR021018): Mediator complex subunit 29
43 MED30interactor110.8673.183Med30 (PF11315, IPR021019): Mediator complex subunit 30
44 MED9interactor180.71221.216Med9 (PF07544, IPR011425): RNA polymerase II transcription mediator complex subunit 9
45 MKS1interactor40.8330.499B9-C2 (PF07162, IPR010796): Ciliary basal body-associated, B9 protein
46 NEK8interactor40.8330.405Pkinase (PF00069, IPR000719): Protein kinase domain
RCC1 (PF00415, IPR000408): Regulator of chromosome condensation (RCC1) repeat
RCC1_2 (PF13540): Regulator of chromosome condensation (RCC1) repeat
47 NPHP1interactor100.50015.725SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
FAM176 (PF14851): FAM176 family
Speriolin_N (PF15058, IPR029385): Speriolin N terminus
DUF4746 (PF15928, IPR031827): Domain of unknown function (DUF4746)
48 NPHP4interactor40.8330.429Corona_nucleoca (PF00937, IPR001218): Coronavirus nucleocapsid protein
49 NXF1interactor170.292126.610NTF2 (PF02136, IPR002075): Nuclear transport factor 2 (NTF2) domain
Tap-RNA_bind (PF09162, IPR015245): Tap, RNA-binding
TAP_C (PF03943, IPR005637, SM00804): TAP C-terminal domain
LRR_8 (PF13855, IPR001611): Leucine rich repeat
50 OFD1protein found in more fusions120.47363.428APG6 (PF04111, IPR007243): Autophagy protein Apg6
Exonuc_VII_L (PF02601, IPR020579): Exonuclease VII, large subunit
GrpE (PF01025, IPR000740): GrpE
NPV_P10 (PF05531, IPR008702): Nucleopolyhedrovirus P10 protein
XhlA (PF10779, IPR019715): Haemolysin XhlA
DUF3372 (PF11852, IPR024561): Domain of unknown function (DUF3372)
LisH_2 (PF16045, IPR006594): LisH
51 PARD6Ainteractor60.46711.003PB1 (PF00564, IPR000270, SM00666): PB1 domain
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
52 PDRG1interactor150.50532.958Prefoldin_2 (PF01920, IPR002777): Prefoldin subunit
TMF_DNA_bd (PF12329, IPR022092): TATA element modulatory factor 1 DNA binding
53 PLEKHM2interactor205.814PH (PF00169, IPR001849, SM00233): PH domain
RUN (PF02759, IPR004012, SM00593): RUN domain
54 POLR1Ainteractor260.357252.659RNA_pol_Rpb1_1 (PF04997, IPR007080): RNA polymerase Rpb1, domain 1
RNA_pol_Rpb1_2 (PF00623, IPR000722): RNA polymerase Rpb1, domain 2
RNA_pol_Rpb1_3 (PF04983, IPR007066): RNA polymerase Rpb1, domain 3
RNA_pol_Rpb1_4 (PF05000, IPR007083): RNA polymerase Rpb1, domain 4
RNA_pol_Rpb1_5 (PF04998, IPR007081): RNA polymerase Rpb1, domain 5
55 POLR1Binteractor130.7317.859RNA_pol_Rpa2_4 (PF06883, IPR009674): RNA polymerase I, Rpa2 specific domain
RNA_pol_Rpb2_1 (PF04563, IPR007644): RNA polymerase beta subunit
RNA_pol_Rpb2_3 (PF04565, IPR007645): RNA polymerase Rpb2, domain 3
RNA_pol_Rpb2_6 (PF00562, IPR007120): RNA polymerase Rpb2, domain 6
RNA_pol_Rpb2_7 (PF04560, IPR007641): RNA polymerase Rpb2, domain 7
56 POLR1Cinteractor260.437169.688RNA_pol_A_bac (PF01000, IPR011262): RNA polymerase Rpb3/RpoA insert domain
57 POLR1Dinteractor170.69114.564RNA_pol_L_2 (PF13656): RNA polymerase Rpb3/Rpb11 dimerisation domain
58 POLR1Einteractor51.0000RNA_pol_I_A49 (PF06870, IPR009668): A49-like RNA polymerase I associated factor
59 POLR2Aprotein found in more fusions460.374507.364RNA_pol_Rpb1_1 (PF04997, IPR007080): RNA polymerase Rpb1, domain 1
RNA_pol_Rpb1_2 (PF00623, IPR000722): RNA polymerase Rpb1, domain 2
RNA_pol_Rpb1_3 (PF04983, IPR007066): RNA polymerase Rpb1, domain 3
RNA_pol_Rpb1_4 (PF05000, IPR007083): RNA polymerase Rpb1, domain 4
RNA_pol_Rpb1_5 (PF04998, IPR007081): RNA polymerase Rpb1, domain 5
RNA_pol_Rpb1_R (PF05001, IPR000684): RNA polymerase Rpb1 C-terminal repeat
60 POLR2Binteractor360.462145.818RNA_pol_Rpb2_1 (PF04563, IPR007644): RNA polymerase beta subunit
RNA_pol_Rpb2_3 (PF04565, IPR007645): RNA polymerase Rpb2, domain 3
RNA_pol_Rpb2_4 (PF04566, IPR007646): RNA polymerase Rpb2, domain 4
RNA_pol_Rpb2_5 (PF04567, IPR007647): RNA polymerase Rpb2, domain 5
RNA_pol_Rpb2_6 (PF00562, IPR007120): RNA polymerase Rpb2, domain 6
RNA_pol_Rpb2_7 (PF04560, IPR007641): RNA polymerase Rpb2, domain 7
61 POLR2Cinteractor370.473192.694RNA_pol_A_bac (PF01000, IPR011262): RNA polymerase Rpb3/RpoA insert domain
62 POLR2Dinteractor260.60365.960RNA_pol_Rpb4 (PF03874, IPR005574): RNA polymerase Rpb4
Tfb4 (PF03850, IPR004600): Transcription factor Tfb4
63 POLR2Eprotein found in more fusions540.307925.758RNA_pol_Rpb5_C (PF01191, IPR000783): RNA polymerase Rpb5, C-terminal domain
RNA_pol_Rpb5_N (PF03871, IPR005571): RNA polymerase Rpb5, N-terminal domain
64 POLR2Ginteractor380.473240.032SHS2_Rpb7-N (PF03876, IPR005576): SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397
S1 (PF00575, IPR003029, SM00316): S1 RNA binding domain
65 POLR2Hinteractor370.446153.981RNA_pol_Rpb8 (PF03870, IPR005570, SM00658): RNA polymerase Rpb8
66 POLR2Iinteractor260.61872.992RNA_POL_M_15KD (PF02150, IPR001529): RNA polymerases M/15 Kd subunit
TFIIS_C (PF01096, IPR001222): Transcription factor S-II (TFIIS)
CpXC (PF14353, IPR025682): CpXC protein
67 POLR2Jinteractor300.515118.126RNA_pol_L_2 (PF13656): RNA polymerase Rpb3/Rpb11 dimerisation domain
68 POLR2Kinteractor220.61932.864DNA_RNApol_7kD (PF03604, IPR006591, SM00659): DNA directed RNA polymerase, 7 kDa subunit
69 POLR2Linteractor270.51088.864RNA_pol_N (PF01194, IPR000268): RNA polymerases N / 8 kDa subunit
70 POLR2Minteractor180.71923.542GCOM2 (PF15328, IPR026213): Putative GRINL1B complex locus protein 2
71 POLR3Ainteractor260.517110.862RNA_pol_Rpb1_1 (PF04997, IPR007080): RNA polymerase Rpb1, domain 1
RNA_pol_Rpb1_2 (PF00623, IPR000722): RNA polymerase Rpb1, domain 2
RNA_pol_Rpb1_3 (PF04983, IPR007066): RNA polymerase Rpb1, domain 3
RNA_pol_Rpb1_4 (PF05000, IPR007083): RNA polymerase Rpb1, domain 4
RNA_pol_Rpb1_5 (PF04998, IPR007081): RNA polymerase Rpb1, domain 5
72 POLR3Binteractor240.54094.605RNA_pol_Rpb2_1 (PF04563, IPR007644): RNA polymerase beta subunit
RNA_pol_Rpb2_3 (PF04565, IPR007645): RNA polymerase Rpb2, domain 3
RNA_pol_Rpb2_4 (PF04566, IPR007646): RNA polymerase Rpb2, domain 4
RNA_pol_Rpb2_5 (PF04567, IPR007647): RNA polymerase Rpb2, domain 5
RNA_pol_Rpb2_6 (PF00562, IPR007120): RNA polymerase Rpb2, domain 6
RNA_pol_Rpb2_7 (PF04560, IPR007641): RNA polymerase Rpb2, domain 7
73 POLR3Cinteractor180.62143.565HTH_9 (PF08221, IPR013197): RNA polymerase III subunit RPC82 helix-turn-helix domain
NIT (PF08376, IPR013587): Nitrate and nitrite sensing
RNA_pol_Rpc82 (PF05645, IPR008806): RNA polymerase III subunit RPC82
HD_4 (PF13328, IPR003607): HD domain
74 POLR3Dinteractor180.68648.238Atrophin-1 (PF03154, IPR002951): Atrophin-1 family
RNA_pol_Rpc4 (PF05132, IPR007811): RNA polymerase III RPC4
75 POLR3Einteractor290.365344.410Sin_N (PF04801, IPR006886): Sin-like protein conserved region
DUF2382 (PF09557, IPR019060): Domain of unknown function (DUF2382)
76 POLR3Finteractor140.8025.740RNA_pol_Rpc34 (PF05158, IPR007832): RNA polymerase Rpc34 subunit
77 POLR3Ginteractor100.8441.671RNA_pol_3_Rpc31 (PF11705, IPR024661): DNA-directed RNA polymerase III subunit Rpc31
78 POLR3GLinteractor21.0000CENP-B_dimeris (PF09026, IPR015115): Centromere protein B dimerisation domain
RNA_pol_3_Rpc31 (PF11705, IPR024661): DNA-directed RNA polymerase III subunit Rpc31
79 POLR3Hinteractor140.8573.239RNA_pol_Rbc25 (PF08292, IPR013238): RNA polymerase III subunit Rpc25
SHS2_Rpb7-N (PF03876, IPR005576): SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397
80 POLR3Kinteractor120.86413.764RNA_POL_M_15KD (PF02150, IPR001529): RNA polymerases M/15 Kd subunit
TFIIS_C (PF01096, IPR001222): Transcription factor S-II (TFIIS)
zf-ribbon_3 (PF13248): zinc-ribbon domain
zf-SAP30 (PF13866, IPR025717): SAP30 zinc-finger
81 PPP1CAsuppressor220.46898.389Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase
STPPase_N (PF16891, IPR031675): Serine-threonine protein phosphatase N-terminal domain
82 PPP1CBinteractor100.46750.360Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase
STPPase_N (PF16891, IPR031675): Serine-threonine protein phosphatase N-terminal domain
83 PPP1CConcoprotein140.53828.014Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase
STPPase_N (PF16891, IPR031675): Serine-threonine protein phosphatase N-terminal domain
84 PPP1R3Ainteractor90.7786.217CBM_21 (PF03370, IPR005036): Carbohydrate/starch-binding module (family 21)
85 PSMB9interactor160.9243.079Proteasome (PF00227, IPR001353): Proteasome subunit
86 RBPMSprotein found in more fusions200RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
87 RECQL5oncoprotein100.9781.227DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
RecQ5 (PF06959, IPR010716): RecQ helicase protein-like 5 (RecQ5)
SRI (PF08236, IPR013257): SRI (Set2 Rpb1 interacting) domain
TFIIS_M (PF07500, IPR003618): Transcription factor S-II (TFIIS), central domain
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
RecQ_Zn_bind (PF16124, IPR032284): RecQ zinc-binding
TAtT (PF16811, IPR031823): TRAP transporter T-component
88 RPAP2interactor260.486127.047NAD_Gly3P_dh_N (PF01210, IPR011128): NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus
RPAP2_Rtr1 (PF04181, IPR007308): Rtr1/RPAP2 family
SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein
89 RPAP3interactor310.346285.506TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
RPAP3_C (PF13877, IPR025986): Potential Monad-binding region of RPAP3
Fis1_TPR_C (PF14853, IPR028061): Fis1 C-terminal tetratricopeptide repeat
90 RPRD1Binteractor170.71314.219CTD_bind (PF04818, IPR006903): RNA polymerase II-binding domain.
Efg1 (PF10153, IPR019310): rRNA-processing protein Efg1
CTK3 (PF12243, IPR024638): CTD kinase subunit gamma CTK3
CREPT (PF16566, IPR032337): Cell-cycle alteration and expression-elevated protein in tumour
91 RUVBL1oncoprotein210.400113.768TIP49 (PF06068, IPR010339): TIP49 C-terminus
92 RUVBL2oncoprotein250.406148.946TIP49 (PF06068, IPR010339): TIP49 C-terminus
93 SDC2protein found in more fusions200Glycophorin_A (PF01102, IPR001195): Glycophorin A
Syndecan (PF01034, IPR027789): Syndecan domain
DUF3275 (PF11679, IPR021693): Protein of unknown function (DUF3275)
94 SEC16Ainteractor40.8331.236APC_r (PF05923): APC repeat
Sec16_C (PF12931, IPR024298): Sec23-binding domain of Sec16
Sec16 (PF12932, IPR024340): Vesicle coat trafficking protein Sec16 mid-region
95 SETXinteractor41.0000ResIII (PF04851, IPR006935): Type III restriction enzyme, res subunit
AAA_11 (PF13086): AAA domain
AAA_12 (PF13087): AAA domain
96 SRConcoprotein160.82912.353Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
SH2 (PF00017, IPR000980, SM00252): SH2 domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
97 SUPT4H1interactor70.52412.824Spt4 (PF06093, IPR022800): Spt4/RpoE2 zinc finger
98 SUPT5Hinteractor190.49172.640KOW (PF00467, IPR005824, SM00739): KOW motif
Ribonuc_P_40 (PF08584, IPR013893): Ribonuclease P 40kDa (Rpp40) subunit
Spt5-NGN (PF03439, IPR005100): Early transcription elongation factor of RNA pol II, NGN section
Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal
DUF3912 (PF13051, IPR025023): Protein of unknown function (DUF3912)
99 SUPT6Hinteractor110.40022.815Afi1 (PF07792, IPR012860): Docking domain of Afi1 for Arf3 in vesicle trafficking
S1 (PF00575, IPR003029, SM00316): S1 RNA binding domain
Tex_N (PF09371, IPR018974): Tex-like protein N-terminal domain
zf-Sec23_Sec24 (PF04810, IPR006895): Sec23/Sec24 zinc finger
Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal
SPT6_acidic (PF14632, IPR028083): Acidic N-terminal SPT6
SH2_2 (PF14633, IPR000980): SH2 domain
HHH_7 (PF14635, IPR032706): Helix-hairpin-helix motif
YqgF (PF14639, IPR028231): Holliday-junction resolvase-like of SPT6
HTH_44 (PF14641, IPR028088): Helix-turn-helix DNA-binding domain of SPT6
PBP1_TM (PF14812, IPR032730): Transmembrane domain of transglycosylase PBP1 at N-terminal
DLD (PF14878, IPR027999): Death-like domain of SPT6
100 TCEB3suppressor140.9232.887Elongin_A (PF06881, IPR010684): RNA polymerase II transcription factor SIII (Elongin) subunit A
Med26 (PF08711, IPR017923): TFIIS helical bundle-like domain
101 TELO2interactor70.9051.553Telomere_reg-2 (PF10193, IPR019337): Telomere length regulation protein
HEAT_2 (PF13646): HEAT repeats
102 TRIOBPinteractor30.33320.466FadA (PF09403, IPR018543): Adhesion protein FadA
OmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like)
PH (PF00169, IPR001849, SM00233): PH domain
bZIP_2 (PF07716, IPR004827, SM00338): Basic region leucine zipper
TMF_DNA_bd (PF12329, IPR022092): TATA element modulatory factor 1 DNA binding
DUF4407 (PF14362, IPR025519): Domain of unknown function (DUF4407)
103 TSC22D4interactor306.461AflR (PF08493, IPR013700): Aflatoxin regulatory protein
TSC22 (PF01166, IPR000580): TSC-22/dip/bun family
104 TTI1interactor80.8574.761Dopey_N (PF04118, IPR007249): Dopey, N-terminal
HEAT (PF02985, IPR000357): HEAT repeat
VHS (PF00790, IPR002014, SM00288): VHS domain
CLASP_N (PF12348, IPR024395): CLASP N terminal
105 TTI2interactor70.8101.517Tti2 (PF10521, IPR018870): Tti2 family
106 TYK2interactor60.8000.404Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
107 URI1protein found in more fusions220.49063.738CENP-B_dimeris (PF09026, IPR015115): Centromere protein B dimerisation domain
Cwf_Cwc_15 (PF04889, IPR006973): Cwf15/Cwc15 cell cycle control protein
Prefoldin (PF02996, IPR004127): Prefoldin subunit
DUF3835 (PF12927, IPR024325): Domain of unknown function (DUF3835)
SCAPER_N (PF16501, IPR032446): S phase cyclin A-associated protein in the endoplasmic reticulum
108 UXTinteractor140.53832.172Prefoldin (PF02996, IPR004127): Prefoldin subunit
109 WDR92interactor130.39740.722WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
Itfg2 (PF15907, IPR031793): Integrin-alpha FG-GAP repeat-containing protein 2
110 XPO1interactor320.280458.538CRM1_C (PF08767, IPR014877, SM01102): CRM1 C terminal
Hydrolase_3 (PF08282, IPR023214): haloacid dehalogenase-like hydrolase
IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain
Xpo1 (PF08389, IPR013598): Exportin 1-like protein
Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region
111 ZNRD1interactor41.0000RecR (PF02132, IPR023628): RecR protein
RNA_POL_M_15KD (PF02150, IPR001529): RNA polymerases M/15 Kd subunit
TFIIS_C (PF01096, IPR001222): Transcription factor S-II (TFIIS)

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